Chronic suppurative otitis media

H8_CHRON_SUPOTITIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H66.1, H66.2, H66.3
  • Hospital discharge: ICD-9 3821
  • Hospital discharge: ICD-8 3811
  • Cause of death: ICD-10 H66.1, H66.2, H66.3
  • Cause of death: ICD-9 3821

2 out of 7 registries used, show all original rules.

2854

4. Check minimum number of events

None

2854

5. Include endpoints

None

2854

6. Filter based on genotype QC (FinnGen only)

2854

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36319 15843 20247
Only index persons 29488 13262 16226
Unadjusted period prevalence (%)
Whole population 0.51 0.45 0.57
Only index persons 0.56 0.49 0.62
Median age at first event (years)
Whole population 11.18 15.82 7.08
Only index persons 10.85 15.70 6.89

-FinnGen-

Key figures

All Female Male
Number of individuals 2854 1437 1417
Unadjusted period prevalence (%) 0.56 0.49 0.62
Median age at first event (years) 28.93 25.48 32.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2575
Matched controls
25742
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
664.5
323.0
443
8
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
1801.7
323.0
564
*
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
323.0
1252
*
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
323.0
470
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
243.4
323.0
427
21
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
277.5
323.0
338
14
H65.3
ICD-10 Finland
Chronic mucoid otitis media
369.3
323.0
376
12
H71
ICD-10 Finland
Cholesteatoma of middle ear
1889.9
323.0
321
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
12.0
278.4
543
559
UDC00
NOMESCO Finland
Ear microscopy
8.7
218.9
511
710
H65.2
ICD-10 Finland
Chronic serous otitis media
498.0
188.8
186
*
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
24.4
181.3
262
119
H66.9
ICD-10 Finland
Otitis media, unspecified
8.8
178.9
412
548
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
164.3
156
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.5
157.6
646
1772
4122
FHL
Tympanostomy (tympanic tube)
95.2
153.2
169
19
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
143.0
136
*
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
80.8
141.2
159
21
4141
FHL
Myringoplasty (also for reasons other than inflammation)
1367.1
134.6
130
*
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
28.7
125.2
172
64
DC1AD
NOMESCO Finland
Temporalbone CT
43.9
123.0
153
37
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
117.6
112
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.9
117.5
976
4504
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
4.9
115.3
418
982
DCD00
NOMESCO Finland
Myringoplasty
1147.1
113.5
110
*
EMB30
NOMESCO Finland
Adenotomy
11.4
113.4
221
211
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
106.0
101
*
DFF00
NOMESCO Finland
Pure tone audiometry
4.6
105.4
403
995
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
81.0
103.1
116
15
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
101.7
97
*
S02CA02
ATC
flumetasone and antiinfectives; otic
5.8
100.0
305
583
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
+∞
95.4
91
*
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
10.4
87.1
177
182
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
86.4
1437
9176
H60.3
ICD-10 Finland
Other infective otitis externa
11.0
85.2
168
163
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
82.7
79
*
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
81.7
78
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.0
80.9
557
2186
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
80.6
77
*
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
49.8
79.3
96
20
H74.1
ICD-10 Finland
Adhesive middle ear disease
781.1
77.7
76
*
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
76.4
73
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
4.6
75.4
285
684
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
72.2
69
*
H65.0
ICD-10 Finland
Acute serous otitis media
14.1
71.2
124
92
H60.8
ICD-10 Finland
Other otitis externa
8.4
71.1
162
203
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
361.9
71.0
71
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
70.1
67
*
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
13.5
69.4
123
95
TDA90
NOMESCO Finland
Removal wax from ear
16.7
67.1
109
68
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
232.6
66.5
68
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
15.1
61.0
103
71
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
6.4
60.9
167
275
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
60.6
58
*
Z97.4
ICD-10 Finland
Presence of external hearing-aid
4.8
58.8
210
472
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
61.5
56.7
66
11
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
56.4
54
*
4451
FHL
Guitar cutting
7.0
55.6
143
215
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
55.4
53
*
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
22.0
55.1
81
38
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.8
53.2
243
688
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
116.5
53.0
57
5
DCD10
NOMESCO Finland
Tympanoplasty
528.3
52.7
52
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
51.2
49
*
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
+∞
48.1
46
*
R5120
NOMESCO Finland
Preparation of an aid
6.2
47.0
131
220
J35.2
ICD-10 Finland
Hypertrophy of adenoids
6.3
46.0
126
207
4151
FHL
Reoperation for chronic otitis media
+∞
46.0
44
*
J01DA08
ATC
[U] cefaclor; oral
2.6
45.5
385
1655
H04
ICPC
Ear discharge
5.5
45.5
139
262
J01DA06
ATC
[U] cefuroxime; systemic
2.4
44.1
421
1932
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
49.1
44.0
53
11
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
43.9
42
*
R01AD08
ATC
fluticasone; nasal
2.0
42.1
699
4088
1450
FHL
Otomicroscopy
31.8
40.2
53
17
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
39.7
38
*
J01DA01
ATC
[U] cefalexin; systemic
1.7
39.1
1528
11764
J01MA02
ATC
ciprofloxacin; systemic
1.8
38.1
928
6164
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
+∞
37.6
36
*
H61.2
ICD-10 Finland
Impacted cerumen
3.4
37.5
195
610
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.5
37.3
322
1393
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
5.1
36.6
119
241
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
3.8
36.6
165
460
J01CA04
ATC
amoxicillin; systemic
1.8
36.6
2041
17351
DEB30
NOMESCO Finland
Radical mastoidectomy
187.6
35.8
37
*
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
79.3
34.9
39
5
DFF15
NOMESCO Finland
Speech audiometry
3.7
32.6
150
426
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
32.4
31
*
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
32.4
31
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.8
31.0
207
768
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.6
30.6
110
249
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
13.5
30.5
53
40
H02AB06
ATC
prednisolone; systemic
1.6
28.8
1074
7881
J35.8
ICD-10 Finland
Other chronic diseases of tonsils and adenoids
11.7
28.6
53
46
S02AA03
ATC
boric acid; otic
9.1
28.4
60
67
H01
ICPC
Ear pain/earache
2.2
28.1
310
1503
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.9
27.4
118
317
H92.1
ICD-10 Finland
Otorrhoea
62.7
27.0
31
5
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.8
26.4
176
652
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
13.9
26.3
45
33
J01DB01
ATC
cefalexin; oral
1.6
26.1
1953
16895
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
263.1
25.7
26
*
J01FA10
ATC
azithromycin; systemic
1.6
25.6
1365
10834
38400
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) acuta
+∞
25.0
24
*
H02AB04
ATC
methylprednisolone; systemic
2.0
24.7
338
1791
ZXA10
NOMESCO Finland
Bilateral
1.8
24.1
439
2586
R03AC02
ATC
salbutamol; inhalant
1.5
23.5
1210
9445
H60
ICD-10 Finland
Otitis externa
3.1
23.0
133
450
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
+∞
22.9
22
*
R5140
NOMESCO Finland
Monitoring the use of the aid
2.2
22.6
240
1139
H92.0
ICD-10 Finland
Otalgia
2.8
22.6
149
547
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.5
22.5
107
313
H73.1
ICD-10 Finland
Chronic myringitis
+∞
21.9
21
*
H66
ICD-10 Finland
Suppurative and unspecified otitis media
3.9
21.9
91
238
J01FA09
ATC
clarithromycin; systemic
1.6
21.6
696
4831
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
7.4
21.4
51
70
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
21.4
464
2879
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
21.0
398
2368
RK520
NOMESCO Finland
NA
13.5
21.0
36
27
4146
FHL
Radical cutting (bridge broken)
+∞
20.9
20
*
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
20.9
20
*
ZXA00
NOMESCO Finland
Right side
1.6
20.8
608
4106
4111
FHL
Ear canal extension
110.9
20.6
22
*
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
12.6
20.3
36
29
DEB00
NOMESCO Finland
Cortical mastoidectomy
+∞
19.8
19
*
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
19.8
19
*
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
+∞
19.8
19
*
J01FF01
ATC
clindamycin; systemic
1.6
19.7
580
3916
H29
ICPC
Ear symptom/complaint other
2.1
19.6
235
1175
4143
FHL
Atticotomy or atticoanthromy through the ear canal
201.4
19.6
20
*
H72
ICD-10 Finland
Perforation of tympanic membrane
46.3
19.2
23
5
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
19.0
605
4159
J01DC02
ATC
cefuroxime; systemic
2.5
18.8
148
604
J01AA02
ATC
doxycycline; systemic
1.5
18.6
1696
14612
DAX08
NOMESCO Finland
Fitting of hearing aid
2.8
18.6
119
432
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.8
18.5
118
427
J32.4
ICD-10 Finland
Chronic pansinusitis
5.7
18.4
53
95
H02AB07
ATC
prednisone; oral
1.8
18.3
317
1824
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.6
18.3
82
230
H60.4
ICD-10 Finland
Cholesteatoma of external ear
20.2
17.7
26
13
R03BA05
ATC
fluticasone; inhalant
1.7
17.7
424
2696
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
17.6
466
3050
RK320
NOMESCO Finland
NA
7.2
17.5
42
59
R01AD09
ATC
mometasone; nasal
1.5
16.9
961
7485
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
16.9
178
843
R06AE07
ATC
cetirizine; oral
1.5
16.8
964
7519
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
16.7
530
3625
ZXA05
NOMESCO Finland
Left side
1.6
16.7
537
3688
R03CC02
ATC
salbutamol; systemic
2.0
16.7
210
1073
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
+∞
16.7
16
*
RK110
NOMESCO Finland
NA
7.5
16.4
38
51
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.7
16.1
70
192
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
15.9
387
2464
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
33.6
15.7
20
6
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
+∞
15.6
15
*
S02CA03
ATC
hydrocortisone and antiinfectives; otic
23.5
15.1
21
9
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
14.9
168
818
H70.0
ICD-10 Finland
Acute mastoiditis
150.8
14.5
15
*
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
150.8
14.5
15
*
RK120
NOMESCO Finland
NA
12.6
14.4
25
20
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
5.7
14.2
40
71
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.4
13.9
115
486
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
13.8
306
1893
RK420
NOMESCO Finland
NA
17.6
13.8
21
12
R03BA02
ATC
budesonide; inhalant
1.6
13.7
373
2446
R03BB04
ATC
tiotropium bromide; inhalant
1.9
13.7
218
1215
R03AC12
ATC
salmeterol; inhalant
2.5
13.7
111
463
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
4.9
13.7
44
91
4742A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Adenoid vegetations
4.1
13.6
52
128
4741B
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PHARYNGICAE]
5.1
13.6
42
83
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
+∞
13.5
13
*
DED00
NOMESCO Finland
Obliteration of cavity after partial excision of mastoid
+∞
13.5
13
*
4129
FHL
Other measure in this category
140.7
13.5
14
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.9
13.3
80
281
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
4.0
13.2
52
132
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.7
13.1
291
1805
J01MA12
ATC
levofloxacin; systemic
1.6
12.9
385
2578
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
12.7
583
4301
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
4.1
12.4
48
120
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
12.4
489
3494
50499
ICD-8 Finland
Deflected nasal septum
3.7
12.3
52
141
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
12.2
564
4164
4221
FHL
Polyp removal from the nasal cavity, sinus puncture or irrigation, or biopsy under general anesthesia or operating room
6.4
12.1
31
49
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.9
12.1
193
1076
J47
ICD-10 Finland
Bronchiectasis
4.0
11.9
47
120
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.5
11.9
556
4108
J33.8
ICD-10 Finland
Other polyp of sinus
3.6
11.9
53
151
J35.1
ICD-10 Finland
Hypertrophy of tonsils
3.4
11.8
56
167
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
4.1
11.5
44
110
J20
ICD-10 Finland
Acute bronchitis
1.8
11.4
199
1145
R03DC03
ATC
montelukast; oral
1.6
11.3
328
2182
H71
ICPC
Acute otitis media/myringitis
3.9
11.2
45
117
4222
FHL
Endonasal etmoidectomy
7.3
11.2
26
36
D07AC01
ATC
betamethasone; topical
1.4
11.0
679
5276
R51.80
ICD-10 Finland
Headache
1.6
11.0
310
2048
J01DC04
ATC
cefaclor; oral
3.7
10.9
46
125
UDC10
NOMESCO Finland
Tympanoscopy
43.5
10.9
13
*
H69.0
ICD-10 Finland
Patulous Eustachian tube
15.5
10.8
17
11
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
7.6
10.6
24
32
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
10.6
429
3072
H83.1
ICD-10 Finland
Labyrinthine fistula
110.4
10.4
11
*
4148
FHL
Radical cutting and cavity filling
+∞
10.4
10
*
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
10.4
10
*
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
32.6
10.3
13
*
S02AA30
ATC
antiinfectives, combinations; otic
2.3
10.3
95
427
H73.0
ICD-10 Finland
Acute myringitis
10.6
10.3
19
18
ZZG00
NOMESCO Finland
Graft of cartilage
23.4
10.2
14
6
49300
ICD-8 Finland
Asthma, bronchiale
2.9
10.2
60
210
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.5
10.2
80
332
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.7
10.2
213
1297
H70
ICPC
Otitis externa
3.3
10.1
50
155
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
3.5
10.0
45
130
RK290
NOMESCO Finland
NA
10.1
10.0
19
19
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
10.0
870
7123
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
5.3
10.0
29
55
R03AC03
ATC
terbutaline; inhalant
1.6
9.9
281
1858
R4135
NOMESCO Finland
Rehabilitation for hearing problems
3.6
9.9
43
121
N02BE01
ATC
paracetamol; systemic, rectal
1.3
9.6
1889
17331
4711A
ICD-9 Finland
Nasal polyps, Polypoid sinus degeneration
10.1
9.5
18
18
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
9.5
961
8029
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
+∞
9.4
9
*
5251
FHL
Hypotension
+∞
9.4
9
*
DCB00
NOMESCO Finland
Excision of lesion of middle ear
+∞
9.4
9
*
EMB10
NOMESCO Finland
Tonsillectomy
1.9
9.4
131
700
4741A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PALATINAE]
6.9
9.3
22
32
M01AE02
ATC
naproxen; oral, rectal
1.3
9.3
1213
10488
4452
FHL
Tonsil surgery
2.5
9.3
70
284
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.7
9.3
60
224
J01FA01
ATC
erythromycin; systemic
1.5
9.1
282
1901
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
9.0
553
4272
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
8.8
92
437
R01AD11
ATC
triamcinolone; nasal
1.7
8.8
168
995
L17
ICPC
Foot/toe symptom/complaint
1.4
8.8
511
3908
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.7
819
6750
J01FA15
ATC
telithromycin; oral
1.7
8.7
181
1104
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
50.1
8.7
10
*
4224
FHL
Endonasal anthrostomy
4.2
8.7
31
74
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
8.6
352
2519
R74
ICPC
Upper respiratory infection acute
1.3
8.5
605
4784
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
4.1
8.5
31
76
R03BB01
ATC
ipratropium bromide; inhalant
2.2
8.4
85
400
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
7.4
8.4
19
26
R06AX13
ATC
loratadine; oral
1.5
8.4
297
2060
3890A
ICD-9 Finland
Deafness, Conductive deafness
90.3
8.4
9
*
R01AD05
ATC
budesonide; nasal
1.8
8.4
144
828
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
4.9
8.4
26
54
1451
FHL
Otomicroscopy and paper place
+∞
8.3
8
*
A02BC02
ATC
pantoprazole; systemic
1.3
8.3
1282
11270
J45
ICD-10 Finland
Asthma
1.6
8.2
191
1201
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.9
8.1
123
679
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
8.1
722
5893
E000001
ATC
NA
1.4
8.1
435
3279
J01FA06
ATC
roxithromycin; oral
1.3
8.1
776
6400
Q35.1
ICD-10 Finland
Cleft hard palate
22.1
8.0
11
5
H91.8
ICD-10 Finland
Other specified hearing loss
4.4
7.9
27
62
R4110
NOMESCO Finland
Physiotherapy
1.4
7.9
509
3956
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.9
7.9
105
554
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
7.8
263
1807
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.8
855
7175
H60.1
ICD-10 Finland
Cellulitis of external ear
3.5
7.8
34
98
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
45.1
7.7
9
*
DCA30
NOMESCO Finland
Exploration of middle ear
45.1
7.7
9
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.8
7.7
121
677
T16
ICD-10 Finland
Foreign body in ear
4.1
7.7
28
69
R01AD12
ATC
fluticasone furoate; nasal
1.3
7.6
561
4449
H60.0
ICD-10 Finland
Abscess of external ear
6.2
7.5
19
31
XG410
NOMESCO Finland
Flow-volume spirometry
2.0
7.5
87
434
DHB20
NOMESCO Finland
Polypectomy of internal nose
3.3
7.4
35
107
H74.0
ICD-10 Finland
Tympanosclerosis
80.3
7.4
8
*
WX110
NOMESCO Finland
Local anesthesy
1.3
7.4
1506
13597
H02
ICPC
Hearing complaint
1.5
7.4
219
1460
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
7.4
140
830
H68.0
ICD-10 Finland
Eustachian salpingitis
13.4
7.4
12
9
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
13.4
7.4
12
9
XF400
NOMESCO Finland
ECG with 12 standard connections
1.4
7.3
332
2427
DEB35
NOMESCO Finland
Radical mastoidectomy with tympanoplasty
+∞
7.3
7
*
Q89.34
ICD-10 Finland
Cartagena syndrome (immotile cilia)
+∞
7.3
7
*
H74.4
ICD-10 Finland
Polyp of middle ear
+∞
7.3
7
*
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
1.9
7.2
106
581
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.9
7.2
109
600
S02CA01
ATC
prednisolone and antiinfectives; otic
30.1
7.1
9
*
J06.80
ICD-10 Finland
Continuously repeating infections of a child
20.1
7.1
10
5
D01AC02
ATC
miconazole; topical
1.7
7.1
149
910
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
7.1
345
2553
E0000UV
ATC
NA
1.3
7.0
810
6816
N05BB01
ATC
hydroxyzine; systemic
1.7
6.9
127
747
H61.8
ICD-10 Finland
Other specified disorders of external ear
3.6
6.9
29
82
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
6.8
372
2805
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.6
6.8
184
1204
Z97.8
ICD-10 Finland
Presence of other specified devices
5.7
6.7
18
32
RK530
NOMESCO Finland
NA
16.7
6.7
10
6
4661A
ICD-9 Finland
Acute bronchitis and bronchiolitis, Acute bronchiolitis
16.7
6.7
10
6
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
2.1
6.7
72
349
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
6.7
251
1765
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.9
6.7
87
456
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
6.6
349
2616
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
6.6
537
4309
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.1
6.6
71
344
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
6.5
88
468
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.5
1200
10648
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
3.6
6.5
27
76
H27
ICPC
Fear of ear disease
3.3
6.5
30
92
B01AB05
ATC
enoxaparin; parenteral
1.3
6.4
547
4419
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.4
1315
11799
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
8.2
6.3
13
16
ZXC10
NOMESCO Finland
Use of laser
2.5
6.3
45
181
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
6.3
2007
18907
R03DA04
ATC
theophylline; systemic, rectal
1.8
6.3
107
618
3858X
ICD-9 Finland
Other disorders of middle ear and mastoid
+∞
6.2
6
*
38200
ICD-8 Finland
Acute / Acute otitis media with mastoiditis
+∞
6.2
6
*
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
6.2
6
*
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
3.0
6.2
32
106
D07AC13
ATC
mometasone; topical
1.3
6.2
532
4299
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
6.2
257
1847
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
6.2
650
5394
R03AC13
ATC
formoterol; inhalant
1.8
6.1
93
517
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
6.1
166
1087
H81.3
ICD-10 Finland
Other peripheral vertigo
2.3
6.1
51
224
S06.0
ICD-10 Finland
Concussion
1.5
6.1
208
1437
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.5
6.0
205
1415
38798
ICD-8 Finland
Other disease of ear and mastoid process, Alii definiti
10.0
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
606
2571
2.72
93.67
2.7
1.7
—
—
—
0
0
457
2464
2.02
37.36
1.8
1.4
—
—
—
0
0
491
3069
1.72
24.28
2.2
2.0
—
—
—
0
0
982
7574
1.45
18.56
6.3
6.1
—
—
—
0
0
1227
10193
1.36
13.80
6.9
6.1
0.7
0.7
%
0.12
1137
9531
1259
10522
1.35
13.52
6.7
6.0
2.9
2.8
%
0.63
1171
9807
1278
10737
1.34
13.12
6.5
5.9
56.3
56.8
%
0.84
1190
10064
1262
10583
1.34
13.12
7.0
6.3
8.6
8.6
%
0.05
1175
9928
1296
10926
1.34
12.93
6.8
6.1
28.7
28.3
%
0.47
1200
10209
1352
11549
1.32
11.98
6.7
6.2
0.2
0.2
e9/l
1.56
1158
10132
1300
11165
1.30
10.59
6.5
5.9
0.0
0.0
e9/l
1.73
1107
9647
1329
11485
1.29
10.18
6.4
5.9
2.1
2.0
e9/l
0.90
1150
10117
1291
11136
1.29
9.95
6.5
5.9
0.6
0.6
e9/l
2.65
1099
9617
152
894
1.74
9.16
2.3
1.4
6.0
17.8
u/ml
—
9
25
1024
8657
1.28
8.95
2.0
2.0
94.7
95.5
pmol/l
0.21
547
4561
1772
16086
1.27
8.34
4.3
4.0
12.4
11.7
mm/h
1.34
1624
14864
211
1384
1.57
8.32
1.5
1.3
477.1
252.9
u/ml
0.79
200
1272
292
2064
1.46
8.07
3.9
4.2
—
—
—
0
0
1804
16496
1.25
7.58
7.6
7.3
79.0
79.6
u/l
0.18
1685
15519
48
200
2.42
7.50
1.8
1.3
2.9
2.9
g/l
0.10
37
140
48
200
2.42
7.50
1.8
1.3
6.1
6.9
g/l
1.18
37
139
48
200
2.42
7.50
1.8
1.3
0.3
0.4
g/l
0.69
37
140
48
202
2.40
7.35
1.9
1.3
—
—
—
0
0
516
4106
1.31
6.89
4.3
3.8
298.2
433.1
ng/l
0.53
398
3126
48
209
2.32
6.84
2.5
2.4
1.5
1.2
e9/l
0.84
30
116
1422
12755
1.23
6.77
5.2
4.8
6.7
6.7
mmol/l
0.44
1315
11857
152
980
1.58
6.50
4.8
5.0
24.6
24.6
mmol/l
0.01
141
924
1102
9662
1.23
6.43
6.7
6.2
1.2
1.2
mmol/l
0.47
973
8745
40
166
2.43
6.36
2.3
2.3
10.3
13.3
%
0.87
21
88
1427
12867
1.22
6.25
9.2
8.9
4.1
4.1
e9/l
0.12
1218
11216
708
5937
1.26
6.17
4.3
4.3
—
—
—
0
0
561
4618
1.27
5.67
1.5
1.5
2.5
2.3
g/l
0.63
317
2804
230
1663
1.42
5.66
2.8
2.7
10.2
10.6
g/l
0.44
215
1507
206
1460
1.44
5.65
1.4
1.4
—
—
—
0
0
1194
10650
1.21
5.64
7.4
6.8
1.2
1.2
mmol/l
0.49
1024
8987
1234
11048
1.21
5.59
6.0
6.0
11.2
12.0
umol/l
1.58
1154
10438
654
5505
1.24
5.42
3.9
4.1
89.4
88.6
%
0.34
637
5368
686
5815
1.24
5.32
3.6
3.2
1656.2
1545.2
ng/l
0.27
578
4963
1047
9260
1.21
5.32
4.9
4.9
35.7
35.7
g/l
0.01
962
8584
2349
22438
1.26
5.32
16.0
13.7
23.3
24.1
mg/l
0.54
1898
17544
63
338
1.88
5.28
1.9
1.7
0.7
0.8
g/l
0.23
47
263
1654
15273
1.20
5.19
4.8
4.3
—
—
—
0
0
209
1512
1.41
5.14
4.7
4.3
5.2
5.1
kpa
0.49
195
1403
36
158
2.29
5.12
2.6
2.5
0.2
0.2
e9/l
0.11
31
131
953
8389
1.20
5.02
2.0
2.1
—
—
—
0
0
206
1494
1.41
5.00
4.8
4.4
7.4
7.4
ph
0.18
16
176
359
2836
1.30
5.00
1.3
1.3
578.9
523.2
titre
0.17
74
570
22
77
2.87
4.92
2.2
2.5
384.3
304.7
e6/l
0.22
14
36
184
1315
1.43
4.86
1.6
1.9
1.3
1.4
g/l
0.18
168
1206
963
8509
1.20
4.83
9.3
9.2
1.2
1.3
inr
0.27
241
2486
1580
14582
1.19
4.82
3.0
3.1
49.1
46.3
u/l
0.52
1474
13634
36
163
2.22
4.78
2.6
2.5
606.9
561.4
e6/l
0.18
31
132
160
1118
1.46
4.77
4.9
4.7
—
—
—
0
0
627
5323
1.23
4.74
2.9
2.7
2389.5
5813.8
umol/l
1.86
532
4627
137
1968
0.68
4.63
4.8
3.8
—
—
—
0
0
100
636
1.59
4.63
3.5
3.3
—
—
—
0
0
194
1416
1.40
4.56
3.0
2.8
4.1
4.1
e9/l
0.05
141
1117
648
7496
0.82
4.42
2.7
2.7
—
—
—
0
0
623
5322
1.22
4.40
2.3
2.3
—
—
—
0
0
363
2933
1.27
4.24
6.4
6.1
1.1
1.1
mmol/l
0.46
336
2716
791
6933
1.19
4.24
2.4
2.4
—
—
—
0
0
213
1604
1.35
4.16
4.2
4.1
102.0
87.3
ng/l
0.62
187
1393
763
6678
1.19
4.14
2.6
2.5
57.1
57.0
u/l
0.01
706
6159
35
167
2.11
4.13
3.6
3.0
27.5
26.6
mu/l
0.05
35
155
38
188
2.03
4.08
1.5
1.3
193675.6
102677.8
e6/l
0.29
22
132
25
104
2.42
4.05
1.7
1.5
1.4
1.2
nmol/l
0.32
18
82
79
493
1.62
4.00
1.8
1.6
20465.2
12499.9
e6/l
0.36
56
357
37
187
1.99
3.78
2.7
2.4
46.8
44.6
%
—
5
23
176
1308
1.37
3.76
3.7
3.3
4.5
4.5
pmol/l
0.47
146
1165
2025
19267
1.18
3.71
5.8
5.4
39.7
39.5
mmol/mol
0.61
1866
17826
715
6282
1.18
3.66
2.1
2.2
218.6
241.9
u/l
0.25
658
5906
152
1110
1.39
3.62
9.2
9.6
24.4
24.3
mmol/l
0.07
140
1039
99
678
1.48
3.36
6.3
7.2
1.6
1.3
mmol/l
0.77
89
585
28
134
2.10
3.33
3.6
3.9
—
—
—
0
0
573
4988
1.19
3.24
1.6
1.5
19.0
20.2
nmol/l
1.30
488
4264
411
3489
1.21
3.06
1.3
1.2
24.5
31.9
iu/ml
1.12
115
1046
657
5815
1.17
3.02
2.4
2.2
2.8
2.9
mg/l
0.63
545
4933
377
3178
1.21
3.02
2.6
2.4
2.3
2.3
g/l
0.04
347
2935
292
2397
1.24
3.01
7.8
7.6
5.2
5.1
kpa
0.61
276
2275
292
2398
1.24
3.00
7.8
7.6
11.6
12.4
kpa
1.45
276
2278
18
75
2.41
2.96
2.0
2.2
—
—
—
0
0
291
2394
1.24
2.95
7.8
7.6
0.9
1.1
mmol/l
0.30
225
1835
39
220
1.78
2.93
3.5
3.5
—
—
—
0
0
223
1782
1.27
2.90
4.1
3.1
191.7
214.5
ng/l
0.43
199
1619
413
3534
1.20
2.83
2.8
3.0
3.0
2.4
e6/l
0.57
222
1951
148
1125
1.33
2.80
9.8
10.7
—
—
—
0
0
1550
14615
1.13
2.77
4.7
4.4
600.4
1666.1
e6/l
0.99
18
204
88
617
1.44
2.71
1.4
1.6
0.2
0.2
g/l
0.17
83
583
740
6657
1.15
2.71
3.6
3.3
7.5
7.8
mmol/l
0.72
606
5643
29
154
1.89
2.65
1.2
2.3
7.7
6.8
mmol/l
0.37
22
107
686
6147
1.15
2.65
4.1
4.1
11.8
9.2
mg/mmol
0.61
435
3955
232
1885
1.25
2.65
1.2
1.2
—
—
—
0
0
787
7125
1.14
2.62
3.3
3.3
2.3
2.4
mmol/l
0.21
680
6224
58
376
1.55
2.62
1.6
1.5
—
—
—
0
0
319
2686
1.21
2.60
26.6
25.4
1.3
1.4
inr
0.40
54
388
399
3446
1.18
2.47
2.6
2.4
12.8
13.1
umol/l
0.48
373
3184
89
638
1.41
2.46
1.4
1.6
1.2
1.2
g/l
0.20
84
604
347
2963
1.19
2.45
2.8
2.5
22.3
22.9
%
0.30
285
2528
431
3750
1.18
2.44
2.7
2.8
1.0
1.3
e6/l
0.72
239
2158
29
159
1.83
2.43
2.8
2.6
748.8
767.2
e6/l
0.05
13
66
239
1969
1.23
2.43
9.2
7.7
10.3
9.4
mmol/l
1.16
230
1882
657
5905
1.15
2.42
4.1
3.8
—
—
—
0
0
625
5603
1.15
2.38
7.0
6.7
—
—
—
0
0
590
5272
1.15
2.36
1.4
1.3
2.3
1.7
u/ml
0.45
124
1344
43
267
1.62
2.35
3.1
2.6
—
—
—
0
0
173
1384
1.27
2.29
5.1
5.3
—
—
—
0
0
19
92
2.07
2.27
1.1
1.0
13.8
10.6
u/ml
—
5
16
68
473
1.45
2.24
7.5
8.6
12.2
11.3
mmol/l
1.12
61
418
254
2126
1.21
2.23
8.5
8.1
95.4
95.6
%
0.31
239
2040
68
474
1.45
2.22
7.5
8.6
105.9
105.3
mmol/l
0.52
61
419
380
3304
1.17
2.18
1.3
1.2
12.7
11.3
u/ml
0.13
121
1270
333
2868
1.18
2.15
1.3
1.2
—
—
—
0
0
526
4697
1.15
2.12
2.4
1.8
1.1
1.3
mg/l
0.66
389
3515
136
1717
0.78
2.11
4.1
3.6
1.2
1.2
mmol/l
0.49
116
1468
12
49
2.45
2.10
1.2
1.1
—
—
—
0
0
42
268
1.58
2.09
2.6
2.7
—
—
—
0
0
382
3339
1.17
2.06
2.1
2.4
30.0
30.0
s
0.05
368
3230
233
1952
1.21
2.04
9.0
8.6
121.4
121.6
g/l
0.05
222
1872
38
238
1.60
2.04
1.6
1.5
60.4
61.7
%
0.07
25
151
396
3474
1.16
2.04
3.9
3.6
0.8
0.8
mmol/l
0.62
363
3239
248
2095
1.20
2.00
1.5
1.4
—
—
—
0
0
1756
16850
1.11
1.97
4.0
3.9
14.7
14.7
pmol/l
0.19
1560
15247
31
187
1.66
1.94
1.7
1.5
1.4
1.3
promille
0.08
25
145
527
5840
0.88
1.92
4.2
3.9
0.0
0.0
estimate
1.08
140
2029
641
5837
1.13
1.91
3.5
3.3
557.6
324.2
mg/l
0.51
423
3788
2079
20150
1.12
1.88
4.8
4.6
2.5
2.0
mu/l
0.39
1889
18477
8
28
2.86
1.86
1.1
1.2
—
—
—
0
0
100
769
1.31
1.85
1.3
1.2
0.2
1.0
u/ml
—
6
63
49
335
1.47
1.82
3.6
3.7
0.8
1.5
%
1.80
39
261
39
254
1.54
1.81
1.3
1.3
—
—
—
0
0
34
215
1.59
1.79
2.9
3.5
56.1
56.0
%
0.01
21
141
678
6217
1.12
1.79
4.0
3.9
7.4
7.4
ph
0.13
91
1187
46
312
1.48
1.78
1.3
1.4
18.5
20.5
u/l
0.19
36
264
38
248
1.54
1.76
3.2
3.8
—
—
—
0
0
22
124
1.78
1.75
1.5
1.4
15.8
24.7
umol/l
0.98
22
117
24
139
1.73
1.75
2.1
3.2
—
—
—
0
0
44
297
1.49
1.75
1.5
1.6
—
—
—
0
0
263
2271
1.17
1.69
1.9
1.8
—
—
—
0
0
42
284
1.49
1.67
6.4
6.9
10.8
11.7
mg/l
0.44
37
261
230
1968
1.18
1.65
9.9
8.2
—
—
—
0
0
1090
10290
1.10
1.60
4.1
4.1
—
—
—
0
0
75
568
1.33
1.58
1.2
1.4
—
—
—
0
0
237
2044
1.17
1.56
2.0
2.4
0.2
0.2
g/l
0.47
223
1906
150
1241
1.22
1.55
5.7
4.8
23.5
23.9
mmol/l
1.02
135
1140
2067
20103
1.10
1.55
3.8
3.7
1.3
1.3
mmol/l
1.62
1884
18423
5
15
3.34
1.52
9.4
4.9
—
—
—
0
0
847
7931
1.10
1.47
3.9
3.6
129.4
55.1
ng/l
0.44
521
5306
26
164
1.59
1.43
2.9
2.3
—
—
—
0
0
80
622
1.29
1.43
1.4
1.4
274.2
291.3
ug/g
0.32
45
347
2113
20604
1.10
1.41
4.5
4.2
5.9
5.9
mmol/l
0.83
1920
18738
73
939
0.77
1.40
1.5
1.6
261.2
306.8
mu/l
1.74
68
853
10
46
2.18
1.40
1.0
1.1
—
—
—
0
0
19
111
1.72
1.39
2.2
2.4
7.4
7.4
ph
—
8
35
50
364
1.38
1.38
1.1
1.1
50.6
1387.9
iu/ml
—
10
98
67
511
1.32
1.38
1.6
1.9
4.4
5.1
iu/l
0.29
22
184
600
6481
0.91
1.38
1.5
1.5
—
—
—
0
0
12
60
2.00
1.38
2.2
1.6
—
—
—
0
0
2190
21400
1.10
1.38
4.7
4.5
2.7
2.7
mmol/l
1.63
2006
19713
554
6007
0.90
1.37
3.3
3.2
—
—
—
0
0
27
174
1.56
1.37
3.0
3.4
21.3
33.6
mg/l
0.44
18
134
122
1004
1.22
1.36
1.8
1.8
1.5
1.5
g/l
0.03
106
874
2290
22441
1.10
1.31
18.2
15.8
139.6
139.6
mmol/l
0.23
2222
21808
47
343
1.38
1.30
1.1
1.1
4.8
8.3
u/ml
0.81
20
150
2294
22495
1.10
1.26
18.4
15.9
4.0
4.0
mmol/l
0.13
2215
21820
25
162
1.55
1.25
1.2
1.2
9.8
4.2
u/ml
—
8
56
18
107
1.69
1.25
1.3
1.4
6.0
5.9
mmol/l
0.08
18
102
44
320
1.38
1.25
1.5
1.3
—
—
—
0
0
542
5007
1.10
1.24
3.6
3.6
—
—
—
0
0
2132
20846
1.09
1.22
4.3
4.1
1.4
1.4
mmol/l
5.89
1949
19216
436
3989
1.11
1.21
1.8
1.8
1134.4
1160.4
nmol/l
0.23
318
2987
279
2488
1.13
1.21
2.4
2.8
7.7
8.4
umol/l
0.26
237
2146
702
6573
1.09
1.21
3.3
3.1
—
—
—
0
0
20
124
1.62
1.20
1.1
1.1
1.1
1.1
ratio
—
5
48
152
1302
1.18
1.15
7.3
7.3
24.3
24.5
mmol/l
0.28
141
1206
29
199
1.46
1.14
3.1
2.7
—
—
—
0
0
7
30
2.34
1.12
1.0
1.0
—
—
—
0
0
50
379
1.32
1.12
1.1
1.1
7.2
5.8
u/ml
0.13
20
154
8
40
2.00
1.12
1.5
1.3
—
—
—
0
0
67
529
1.27
1.12
1.3
1.2
8.0
2.9
u/ml
—
7
53
38
515
0.73
1.10
1.5
1.4
—
—
—
0
0
17
104
1.64
1.09
2.8
2.8
—
—
—
0
0
8
41
1.95
1.08
1.9
1.7
—
—
—
0
0
27
386
0.70
1.08
1.1
1.1
—
—
—
0
0
38
512
0.74
1.07
1.5
1.4
—
—
—
0
0
826
7831
1.08
1.04
3.9
3.7
59.2
99.4
e6/l
1.45
590
5557
33
452
0.73
1.04
4.2
3.1
1.6
1.6
mmol/l
0.02
33
437
709
6686
1.08
1.03
3.4
3.3
40.1
78.3
e6/l
1.75
547
5180
7
34
2.06
1.03
3.4
1.8
93.0
24.4
pmol/l
—
7
29
44
333
1.33
1.02
1.2
1.5
—
—
—
0
0
40
299
1.34
1.00
1.1
1.2
—
—
—
0
0
9
48
1.88
1.00
1.6
2.0
—
—
—
0
0
1843
18870
0.93
1.00
19.7
16.6
13.8
13.6
%
3.65
1806
18442
7
35
2.00
1.00
1.0
1.1
—
—
—
0
0
296
2686
1.11
0.99
1.2
1.3
—
—
—
0
0
24
164
1.47
0.99
1.3
1.3
1.3
1.3
u/ml
0.00
13
69
40
527
0.76
0.99
1.6
1.5
—
—
—
0
0
23
156
1.48
0.98
1.1
1.1
—
—
—
0
0
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
242
2179
1.12
0.94
5.5
4.3
1.7
1.8
mmol/l
0.12
188
1733
7
37
1.89
0.94
1.7
1.5
—
—
—
0
0
249
2754
0.89
0.93
1.6
1.7
—
—
—
0
0
6
27
2.22
0.93
2.0
7.4
—
—
—
0
0
44
339
1.30
0.92
1.7
1.4
—
—
—
0
0
2142
21030
1.07
0.92
4.3
4.1
4.5
4.6
mmol/l
4.57
1968
19487
511
4781
1.08
0.91
3.8
4.0
1.0
1.0
kg/l
0.58
97
719
80
668
1.20
0.86
1.3
1.1
—
—
—
0
0
109
936
1.17
0.85
1.3
1.3
—
—
—
0
0
28
379
0.74
0.85
1.1
1.1
—
—
—
0
0
41
524
0.78
0.84
4.0
4.5
—
—
—
0
0
32
422
0.76
0.83
4.3
3.2
7.2
7.6
mmol/l
0.42
32
409
6
115
0.52
0.82
2.5
1.8
—
—
—
0
0
351
3787
0.92
0.82
3.0
3.0
1.0
0.8
ug/l
0.97
246
2483
79
664
1.20
0.80
7.7
6.0
1.5
1.4
mg/l
0.34
74
612
114
989
1.16
0.80
1.2
1.1
—
1.8
—
0
12
60
491
1.23
0.80
2.3
2.1
128.4
130.2
g/l
0.21
40
362
66
546
1.21
0.79
1.2
1.1
1.1
2.5
u/ml
0.88
30
254
2384
23538
1.08
0.78
11.0
9.8
26.5
26.3
u/l
0.12
2293
22681
0
27
0.00
0.77
0.0
1.3
—
819.7
—
0
7
194
1749
1.12
0.77
1.4
1.4
—
—
—
0
0
11
67
1.64
0.75
1.8
1.8
—
—
—
0
0
632
6013
1.07
0.72
3.3
3.1
—
—
—
0
0
5
25
2.00
0.72
1.4
2.0
62.4
43.4
umol/l
—
5
25
13
195
0.67
0.72
1.0
1.1
—
—
—
0
0
10
60
1.67
0.72
1.6
1.9
—
—
—
0
0
57
471
1.21
0.71
1.1
1.1
2.2
3.9
u/ml
0.61
12
127
7
40
1.75
0.71
1.0
1.2
—
—
—
0
0
249
2287
1.10
0.71
1.3
1.3
—
—
—
0
0
45
363
1.24
0.70
3.8
5.2
401.0
368.6
umol/l
0.95
38
321
89
1028
0.86
0.70
1.4
1.5
18.3
22.0
iu/l
0.57
72
849
38
473
0.80
0.66
3.3
2.3
16.9
16.3
%
0.48
23
232
492
4660
1.07
0.66
2.7
2.6
5.7
5.9
e6/l
0.14
431
4113
92
801
1.15
0.65
1.1
1.1
—
—
—
0
0
13
189
0.69
0.63
1.4
1.2
—
—
—
0
0
15
104
1.44
0.62
1.3
2.9
172.6
144.9
umol/l
—
8
57
311
2905
1.08
0.62
1.6
1.6
—
—
—
0
0
225
2074
1.09
0.61
2.2
2.5
28.4
38.8
u/l
3.13
192
1777
237
2190
1.09
0.61
5.7
4.3
5.9
5.8
kpa
0.60
232
2126
5
30
1.67
0.61
3.8
8.8
—
—
—
0
0
122
1362
0.89
0.60
1.3
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
2.8
—
0
13
32
254
1.26
0.59
1.3
1.2
—
43.3
—
0
11
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
14
97
1.45
0.59
3.7
3.1
—
—
—
0
0
227
2099
1.09
0.58
2.1
2.2
373.1
369.4
nmol/l
0.10
207
1922
99
1117
0.88
0.58
1.8
1.6
—
—
—
0
0
27
343
0.79
0.58
1.6
1.5
0.2
0.4
nmol/l
1.86
21
284
92
810
1.14
0.58
1.6
1.6
—
—
—
0
0
178
1629
1.10
0.58
4.0
3.9
0.5
0.6
%
0.43
40
354
18
132
1.37
0.57
1.0
1.0
—
—
—
0
0
156
1423
1.10
0.55
3.2
2.9
—
—
—
0
0
19
142
1.34
0.54
1.2
1.1
—
—
—
0
0
472
4949
0.94
0.54
5.2
4.3
—
—
—
0
0
27
213
1.27
0.54
1.1
1.1
—
—
—
0
0
59
506
1.17
0.53
1.1
1.2
—
—
—
0
0
80
703
1.14
0.53
5.8
4.7
9.0
8.7
kpa
0.71
75
660
39
322
1.21
0.53
1.1
1.2
—
—
—
0
0
15
108
1.39
0.53
3.6
3.0
—
—
—
0
0
94
836
1.13
0.52
6.5
6.0
0.9
0.9
%
0.51
87
774
10
66
1.52
0.52
2.3
2.8
—
—
—
0
0
407
3866
1.06
0.52
2.8
3.0
2.5
2.4
mmol/l
0.21
357
3386
9
63
1.43
0.52
1.4
2.5
—
—
—
0
0
9
63
1.43
0.52
1.3
1.4
4.0
3.4
mmol/l
—
9
57
310
2921
1.07
0.51
2.3
2.6
175.1
128.0
ug/g
0.99
241
2305
11
157
0.70
0.51
1.0
1.1
—
—
—
0
0
195
1807
1.08
0.50
2.2
2.4
7.0
6.9
ug/l
0.01
166
1598
2127
21017
1.05
0.50
17.8
14.6
40.1
39.9
%
0.31
1561
15463
39
325
1.20
0.49
1.1
1.1
0.0
0.5
u/ml
—
8
89
637
6137
1.05
0.49
3.4
3.2
0.3
0.4
e6/l
2.09
484
4684
2536
25175
1.07
0.49
22.7
19.8
30.1
30.2
pg
0.47
2500
24779
41
344
1.19
0.49
1.2
1.2
90.4
45.7
u/l
0.35
35
295
2537
25187
1.06
0.48
22.9
19.9
7.0
6.8
e9/l
2.87
2464
24423
7
46
1.52
0.48
1.0
1.2
2.1
6.8
u/ml
—
7
37
11
76
1.45
0.48
1.2
1.3
—
—
—
0
0
56
484
1.16
0.48
2.7
2.4
52.8
92.9
ug/min
0.92
29
298
2536
25178
1.06
0.48
22.8
19.9
4.5
4.5
e12/l
0.23
2465
24422
1035
10085
1.04
0.48
3.1
2.8
117.0
116.0
ug/l
0.05
951
9324
32
263
1.22
0.47
1.5
1.6
—
—
—
0
0
32
263
1.22
0.47
1.5
1.6
—
—
—
0
0
32
263
1.22
0.47
1.5
1.6
—
—
—
0
0
32
263
1.22
0.47
1.5
1.6
—
—
—
0
0
2533
25151
1.06
0.46
22.9
19.9
252.9
250.6
e9/l
1.02
2474
24457
21
164
1.28
0.46
1.0
1.2
0.9
3.0
u/ml
—
8
70
192
1786
1.08
0.46
4.3
4.0
0.8
0.9
%
0.23
61
491
2354
23329
1.05
0.46
14.6
12.8
—
—
—
0
0
2535
25173
1.06
0.46
22.8
19.8
90.5
90.5
fl
0.01
2501
24780
48
412
1.17
0.45
1.1
1.1
—
—
—
0
0
154
1421
1.09
0.45
2.5
2.4
33.1
22.9
au/ml
—
8
89
96
865
1.11
0.45
1.2
1.2
—
—
—
0
0
97
1073
0.90
0.45
3.9
3.6
—
—
—
0
0
48
413
1.16
0.44
1.1
1.1
—
—
—
0
0
64
563
1.14
0.44
4.5
3.1
24.7
24.8
mmol/l
0.12
57
486
2536
25189
1.06
0.44
23.0
20.0
135.2
135.5
g/l
0.52
2501
24797
189
1762
1.08
0.44
1.9
2.2
12.1
12.7
nmol/l
0.43
160
1566
20
157
1.28
0.43
1.2
1.3
—
—
—
0
0
37
312
1.19
0.43
1.1
1.2
3.1
4.7
u/ml
0.38
14
138
58
508
1.14
0.43
1.5
1.5
—
—
—
0
0
14
185
0.76
0.43
1.3
1.6
—
—
—
0
0
9
131
0.69
0.43
1.3
1.2
—
—
—
0
0
37
436
0.85
0.43
1.5
1.3
—
—
—
0
0
203
2166
0.93
0.42
1.3
1.3
—
—
—
0
0
54
471
1.15
0.42
6.0
3.8
—
—
—
0
0
42
359
1.17
0.42
4.2
3.2
—
—
—
0
0
87
784
1.11
0.42
1.3
1.3
200.8
227.5
miu/ml
0.31
29
364
270
2555
1.06
0.41
2.8
2.7
1.7
1.7
%
0.01
225
2253
93
842
1.11
0.41
6.5
5.9
1.9
1.6
%
1.16
86
779
0
15
0.00
0.41
0.0
1.5
—
1.4
—
0
9
30
250
1.20
0.40
1.6
2.3
—
—
—
0
0
70
782
0.89
0.40
1.4
1.6
10.3
8.3
u/l
0.49
57
621
39
334
1.17
0.39
1.2
1.1
4.3
2.3
u/ml
—
10
156
49
428
1.15
0.39
2.2
3.3
0.8
0.8
nmol/l
0.06
34
331
12
89
1.35
0.37
1.2
1.4
—
—
—
0
0
50
439
1.14
0.37
3.3
3.3
4.2
4.1
e9/l
0.04
50
439
163
1741
0.93
0.37
3.4
3.5
—
—
—
0
0
48
421
1.14
0.36
1.2
1.6
—
—
—
0
0
103
946
1.09
0.36
2.2
1.9
—
—
—
0
0
22
267
0.82
0.36
3.0
2.5
106.4
105.2
mmol/l
0.67
22
262
22
267
0.82
0.36
3.0
2.5
4.0
4.1
mmol/l
1.02
22
262
23
189
1.22
0.36
4.7
4.9
13.3
11.1
%
1.30
23
189
35
300
1.17
0.36
1.5
1.6
—
—
—
0
0
196
1848
1.06
0.35
2.8
2.7
72.9
69.6
e9/l
0.44
142
1387
94
861
1.09
0.35
2.3
2.6
21.1
21.7
s
0.67
84
765
14
108
1.30
0.35
4.4
3.0
812.5
1258.5
u/ml
0.70
14
108
6
43
1.40
0.35
8.0
5.2
66.6
53.3
g/mol
—
6
35
6
44
1.36
0.34
1.2
1.7
—
—
—
0
0
6
44
1.36
0.34
3.5
8.0
—
—
—
0
0
863
8435
1.03
0.34
3.4
3.4
—
5.9
—
0
6
180
1697
1.06
0.33
4.5
4.1
0.1
0.1
%
0.28
56
450
51
453
1.13
0.33
1.6
2.2
1.0
0.8
nmol/l
1.22
44
382
51
453
1.13
0.33
4.1
3.6
58.9
57.6
%
0.38
51
453
200
1893
1.06
0.33
9.0
7.2
1.3
1.4
mmol/l
0.58
194
1821
75
683
1.10
0.32
1.1
1.2
—
—
—
0
0
40
351
1.14
0.31
1.2
1.2
—
—
—
0
0
194
1838
1.06
0.31
1.5
1.4
—
—
—
0
0
146
1372
1.07
0.31
1.2
1.2
—
—
—
0
0
110
1023
1.08
0.31
4.4
3.1
1.5
1.2
%
1.62
110
1015
29
249
1.17
0.30
1.4
1.3
—
—
—
0
0
63
572
1.10
0.30
4.8
3.4
—
—
—
0
0
90
832
1.08
0.29
2.2
1.9
1.4
1.7
ug/l
0.13
76
729
26
222
1.17
0.29
1.4
1.5
—
—
—
0
0
1451
14695
0.97
0.29
3.8
3.7
—
—
—
0
0
115
1076
1.07
0.28
2.6
2.4
—
—
—
0
0
22
259
0.85
0.28
3.0
2.5
—
—
—
0
0
96
894
1.08
0.27
4.8
3.3
—
—
—
0
0
42
469
0.89
0.27
1.6
1.8
205.8
204.2
pmol/l
0.02
37
447
88
817
1.08
0.27
3.0
2.6
—
—
—
0
0
45
500
0.90
0.27
1.1
1.1
—
—
—
0
0
78
721
1.08
0.26
2.2
3.4
1448.2
5475.5
u/ml
0.50
69
615
50
454
1.10
0.25
1.2
1.3
—
—
—
0
0
58
531
1.09
0.25
1.2
1.3
212.0
234.9
u/ml
0.39
35
307
53
483
1.10
0.25
1.4
1.8
—
—
—
0
0
78
839
0.93
0.24
5.3
4.4
—
—
—
0
0
9
77
1.17
0.24
3.7
4.5
—
—
—
0
0
6
82
0.73
0.24
1.0
1.1
—
—
—
0
0
176
1681
1.05
0.24
1.9
2.6
66.8
66.5
g/l
0.23
161
1529
6
84
0.71
0.24
1.0
1.0
—
—
—
0
0
167
1597
1.05
0.22
4.4
4.2
0.1
0.5
%
0.80
42
377
450
4389
1.03
0.22
3.0
2.8
558.5
553.7
mosm/kgh2o
0.17
381
3750
5
41
1.22
0.22
1.2
1.0
—
—
—
0
0
5
41
1.22
0.22
2.0
1.3
—
—
—
0
0
56
606
0.92
0.21
5.1
4.1
7.4
7.4
ph
0.41
46
502
0
10
0.00
0.21
0.0
1.0
—
0.1
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
5.1
—
0
6
0
12
0.00
0.21
0.0
1.2
—
0.0
—
0
6
51
469
1.09
0.21
1.5
1.5
101.7
105.7
u/ml
—
9
82
5
43
1.16
0.21
1.6
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
15.9
—
0
8
17
145
1.17
0.20
1.1
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
40.8
—
0
8
32
355
0.90
0.20
1.4
1.6
—
—
—
0
0
11
90
1.22
0.19
1.3
1.1
—
—
—
0
0
47
509
0.92
0.19
5.4
4.4
2.2
2.5
mmol/l
0.41
35
331
37
337
1.10
0.19
1.8
2.4
3.5
9.5
umol/l
2.69
24
257
18
156
1.15
0.18
1.1
1.2
—
—
—
0
0
7
59
1.19
0.18
3.1
2.4
1.4
1.9
mmol/l
—
7
46
1066
10777
0.98
0.17
5.0
4.9
0.0
0.0
estimate
0.50
149
2106
104
992
1.05
0.17
4.5
3.1
0.7
0.6
%
0.18
99
951
7
63
1.11
0.17
2.3
2.5
—
—
—
0
0
52
485
1.07
0.16
1.1
1.1
0.5
1.7
u/ml
1.62
21
233
43
464
0.93
0.16
1.8
3.6
—
—
—
0
0
8
68
1.18
0.16
1.0
1.3
—
—
—
0
0
58
618
0.94
0.16
1.7
3.4
1.3
1.7
ratio
—
6
49
8
69
1.16
0.16
1.0
1.0
—
—
—
0
0
27
244
1.11
0.16
1.4
1.5
332.6
341.8
pmol/l
0.04
20
185
8
72
1.11
0.16
1.0
1.0
6.4
8.4
mu/l
—
8
61
23
206
1.12
0.16
1.3
2.1
—
—
—
0
0
54
506
1.07
0.15
1.1
1.1
3.9
6.5
u/ml
0.74
27
287
8
73
1.10
0.15
1.3
1.2
—
—
—
0
0
121
1162
1.04
0.15
1.2
1.1
113.9
145.9
titre
—
8
28
51
477
1.07
0.15
2.1
3.0
33.7
34.0
umol/l
0.04
43
404
10
119
0.84
0.15
1.2
1.2
—
—
—
0
0
114
1094
1.04
0.15
2.6
2.3
2192.3
5374.8
u/l
1.63
49
399
14
121
1.16
0.15
1.2
1.7
—
—
—
0
0
671
6618
1.02
0.14
4.7
4.9
2.9
3.7
ug/l
0.42
580
5911
19
169
1.12
0.14
1.1
1.3
17.5
64.7
pmol/l
—
6
52
16
141
1.14
0.13
1.1
1.0
—
—
—
0
0
12
103
1.17
0.13
1.2
1.2
—
—
—
0
0
43
402
1.07
0.13
3.3
3.6
2360.8
991.9
u/ml
0.30
38
376
1068
10775
0.99
0.13
3.7
3.6
0.0
0.0
estimate
0.80
140
2075
132
1276
1.04
0.13
1.2
1.2
—
—
—
0
0
11
94
1.17
0.13
1.0
1.0
—
—
—
0
0
1954
19451
1.01
0.12
20.5
17.4
332.5
333.0
g/l
1.45
1943
19269
60
570
1.05
0.12
2.5
2.2
10.7
11.3
mg/l
0.15
53
526
12
104
1.15
0.12
1.1
1.1
422.6
209.9
iu/ml
0.59
12
104
10
116
0.86
0.12
6.6
6.8
—
—
—
0
0
522
5289
0.98
0.11
1.7
1.6
1.4
1.4
mmol/l
0.06
439
4475
24
220
1.09
0.11
1.1
1.1
—
—
—
0
0
37
394
0.94
0.11
1.1
1.2
—
—
—
0
0
28
260
1.08
0.10
3.1
2.8
18.4
20.4
nmol/l
0.56
28
247
52
495
1.05
0.10
3.0
3.4
30.2
27.2
mg/l
0.17
29
318
22
202
1.09
0.10
1.2
1.0
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
44
1.14
0.10
1.6
1.9
2.4
4.5
nmol/l
—
5
44
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
151
1547
0.97
0.10
1.3
1.2
170.4
138.6
iu/ml
0.45
62
585
12
106
1.13
0.09
1.6
1.6
—
—
—
0
0
16
145
1.10
0.09
1.2
1.1
—
—
—
0
0
83
803
1.03
0.09
3.1
3.5
0.3
0.3
g/l
0.24
33
351
5
62
0.81
0.08
1.6
1.4
—
—
—
0
0
17
156
1.09
0.08
1.1
1.3
32.6
36.2
mmol/l
0.30
17
141
186
1827
1.02
0.07
5.1
3.8
5.1
4.7
kpa
1.37
181
1773
6
72
0.83
0.07
1.0
1.2
—
—
—
0
0
7
84
0.83
0.07
1.0
1.2
—
0.1
—
0
8
13
118
1.10
0.07
1.2
1.3
—
—
—
0
0
9
88
1.02
0.07
1.3
1.2
—
—
—
0
0
8
93
0.86
0.06
1.0
1.1
—
—
—
0
0
503
4987
1.01
0.06
1.8
1.9
—
—
—
0
0
14
128
1.09
0.06
3.6
2.8
39.5
42.4
%
—
8
40
12
132
0.91
0.06
1.5
1.7
—
—
—
0
0
38
364
1.04
0.06
1.5
1.2
—
—
—
0
0
9
104
0.86
0.06
2.7
2.8
—
—
—
0
0
9
104
0.86
0.06
5.3
5.5
—
—
—
0
0
78
760
1.03
0.06
2.4
2.3
1408.1
484.0
ug/l
0.43
72
711
1084
10887
0.99
0.06
3.7
3.6
0.0
0.0
estimate
1.32
141
2048
20
213
0.94
0.06
1.4
1.2
—
—
—
0
0
23
243
0.95
0.05
1.7
2.0
—
—
—
0
0
62
637
0.97
0.05
1.7
3.4
35.3
80.8
mg/l
1.30
48
523
11
100
1.10
0.05
1.1
1.1
1403.7
1555.6
miu/ml
0.15
11
100
24
252
0.95
0.05
1.2
1.3
—
—
nmol/l
—
0
0
393
3958
0.99
0.04
1.6
1.6
—
—
—
0
0
27
282
0.96
0.04
2.7
2.5
—
—
—
0
0
62
635
0.98
0.04
1.7
3.4
41.7
59.7
mg/l
0.95
48
520
202
1998
1.01
0.04
3.7
4.2
16.0
17.5
ug/l
0.06
153
1632
10
91
1.10
0.04
2.4
1.7
—
—
—
0
0
445
4477
0.99
0.04
1.7
1.7
14731289.1
25852777.1
pmol/l
0.30
353
3725
11
101
1.09
0.04
2.2
2.5
1845.5
1993.3
ml
0.22
11
90
27
259
1.04
0.04
1.1
1.3
—
—
—
0
0
65
664
0.98
0.04
14.2
10.1
—
—
—
0
0
84
825
1.02
0.04
1.0
1.1
—
—
—
0
0
52
533
0.98
0.04
1.5
1.8
1343.4
859.4
e6/l
0.26
41
431
52
533
0.98
0.04
1.5
1.8
50.0
14.9
e6/l
0.37
40
414
27
260
1.04
0.03
1.7
1.7
—
—
—
0
0
139
1375
1.01
0.03
1.6
2.4
—
—
—
0
0
50
489
1.02
0.03
5.4
3.7
—
—
—
0
0
10
108
0.93
0.03
1.0
1.3
145.9
138.5
nmol/l
—
10
108
130
1312
0.99
0.02
2.3
2.3
—
—
—
0
0
267
2683
0.99
0.02
1.6
1.5
—
—
—
0
0
125
1239
1.01
0.02
3.6
2.4
—
—
—
0
0
27
262
1.03
0.02
1.6
1.4
1263.4
1683.2
e6/l
0.58
19
190
105
1040
1.01
0.01
3.8
2.5
—
—
—
0
0
42
412
1.02
0.01
3.9
2.7
—
—
—
0
0
15
157
0.96
0.01
1.1
1.4
—
—
—
0
0
50
508
0.98
0.01
3.1
2.2
—
—
—
0
0
35
357
0.98
0.01
1.6
1.7
—
—
—
0
0
11
104
1.06
0.01
28.8
4.9
54.5
72.9
mg/l
—
6
78
133
1337
0.99
0.00
3.5
2.4
—
—
—
0
0
21
204
1.03
0.00
1.8
1.4
—
—
—
0
0
11
105
1.05
0.00
2.5
1.5
—
—
—
0
0
23
234
0.98
0.00
1.7
1.4
20107.8
87162.2
e6/l
1.34
11
135
10
95
1.05
0.00
5.0
13.1
—
—
—
0
0
22
219
1.00
0.00
1.5
1.4
—
—
—
0
0
133
1334
1.00
0.00
3.5
2.2
—
—
—
0
0
28
284
0.99
0.00
1.2
1.3
0.6
0.6
nmol/l
0.48
28
271
10
99
1.01
0.00
1.3
1.6
—
—
—
0
0
11
106
1.04
0.00
1.2
1.2
—
—
—
0
0
18
181
0.99
0.00
1.6
1.4
37.8
29.8
%
0.37
12
111
993
9925
1.00
0.00
9.6
9.3
0.0
0.0
e9/l
0.00
786
8067
16
155
1.03
0.00
17.8
13.4
705.8
786.5
nmol/l
0.28
16
149
26
263
0.99
0.00
1.3
1.2
—
—
—
0
0
62
622
1.00
0.00
1.4
2.3
38.1
37.5
g/l
0.26
53
538
133
1325
1.00
0.00
3.5
2.4
—
—
—
0
0
21
212
0.99
0.00
2.2
2.3
—
—
—
0
0
11
113
0.97
0.00
4.5
1.3
178.2
348.2
u/l
0.75
11
101
22
220
1.00
0.00
1.2
1.1
—
—
—
0
0
39
392
0.99
0.00
1.4
1.4
61.6
65.3
mmol/l
0.19
30
319
25
253
0.99
0.00
1.6
1.5
289.0
282.1
mosm/kgh2o
0.67
16
184
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1.1
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
1.5
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
8.7
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.0
1.0
—
0.5
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
58
0.86
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.0
1.0
3.4
3.3
kpa
—
5
47
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
98
0.92
0.00
2.3
2.0
—
—
—
0
0
5
52
0.96
0.00
2.2
2.3
17.0
16.4
umol/l
—
5
52
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
1044.0
—
0
8

Mortality – FinRegistry

Association

Association between endpoint H8_CHRON_SUPOTITIS and mortality.

Females

Parameter HR [95% CI] p-value
H8_CHRON_SUPOTITIS 1.218 [1.07, 1.39] 0.003
Birth year 0.994 [0.99, 1.0] 0.171

During the follow-up period (1.1.1998 — 31.12.2019), 566 out of 6742 females with H8_CHRON_SUPOTITIS died.

Males

Parameter HR [95% CI] p-value
H8_CHRON_SUPOTITIS 1.217 [1.06, 1.4] 0.006
Birth year 0.985 [0.98, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 673 out of 8885 males with H8_CHRON_SUPOTITIS died.

Mortality risk

Mortality risk for people of age

years, who have H8_CHRON_SUPOTITIS.

N-year risk Females Males
1 0.116% 0.167%
5 0.661% 1.295%
10 1.752% 3.212%
15 3.385% 6.503%
20 6.301% 10.844%

Relationships between endpoints

Index endpoint: H8_CHRON_SUPOTITIS – Chronic suppurative otitis media

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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