Chronic suppurative otitis media

H8_CHRON_SUPOTITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H66.1, H66.2, H66.3
  • Hospital discharge: ICD-9 3821
  • Hospital discharge: ICD-8 3811
  • Cause of death: ICD-10 H66.1, H66.2, H66.3
  • Cause of death: ICD-9 3821

2 out of 7 registries used, show all original rules.

2876

4. Check minimum number of events

None

2876

5. Include endpoints

None

2876

6. Filter based on genotype QC (FinnGen only)

2767

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36319 15843 20247
Only index persons 29488 13262 16226
Unadjusted period prevalence (%)
Whole population 0.51 0.45 0.57
Only index persons 0.56 0.49 0.62
Median age at first event (years)
Whole population 11.18 15.82 7.08
Only index persons 10.85 15.70 6.89

-FinnGen-

Key figures

All Female Male
Number of individuals 2767 1396 1371
Unadjusted period prevalence (%) 0.56 0.50 0.63
Median age at first event (years) 29.20 25.96 32.51

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2876
Matched controls
28750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
DC1AD
NOMESCO Finland
Temporalbone CT
62.4
317.1
176
30
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
51.8
312.8
180
37
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
307.7
515
*
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
307.7
1385
*
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
844.2
307.7
653
10
H66.9
ICD-10 Finland
Otitis media, unspecified
8.7
307.7
517
707
4122
FHL
Tympanostomy (tympanic tube)
131.3
307.7
196
16
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
342.2
307.7
411
14
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
1198.4
307.7
497
5
H65.3
ICD-10 Finland
Chronic mucoid otitis media
273.9
307.7
441
19
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
29.7
307.7
318
120
H71
ICD-10 Finland
Cholesteatoma of middle ear
4121.4
307.7
372
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
10.5
307.7
669
803
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
42.3
307.7
212
54
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
254.6
307.7
487
23
H65.2
ICD-10 Finland
Chronic serous otitis media
155.6
307.7
216
15
UDC00
NOMESCO Finland
Ear microscopy
8.5
307.7
604
874
EMB30
NOMESCO Finland
Adenotomy
13.4
261.4
255
208
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.4
239.9
753
2147
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
41.4
228.0
138
35
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
4.8
185.1
469
1116
H60.3
ICD-10 Finland
Other infective otitis externa
10.7
184.0
206
206
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
183.3
174
*
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
10.3
176.9
203
210
H65.0
ICD-10 Finland
Acute serous otitis media
16.0
174.4
151
99
S02CA02
ATC
flumetasone and antiinfectives; otic
5.9
174.4
340
642
DFF00
NOMESCO Finland
Pure tone audiometry
4.4
172.2
500
1321
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
33.6
171.9
110
34
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
15.9
165.7
144
95
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
157.8
150
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.8
148.2
1108
5223
4141
FHL
Myringoplasty (also for reasons other than inflammation)
502.5
145.8
144
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
16.4
138.3
118
75
DCD00
NOMESCO Finland
Myringoplasty
1385.5
136.6
132
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
4.3
132.0
377
975
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
131.2
125
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
122.8
117
*
H60.8
ICD-10 Finland
Other otitis externa
6.8
119.6
194
303
TDA90
NOMESCO Finland
Removal wax from ear
12.1
119.1
121
104
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
117.5
112
*
4451
FHL
Guitar cutting
8.1
115.3
159
207
Z97.4
ICD-10 Finland
Presence of external hearing-aid
4.9
111.8
261
573
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
23.9
107.4
77
33
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.8
106.4
642
2641
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
105.9
101
*
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
5.6
105.8
211
403
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
1034.1
102.8
100
*
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
15.1
102.6
91
62
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
43.0
98.4
59
14
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
96.0
1669
10933
H74.1
ICD-10 Finland
Adhesive middle ear disease
927.2
92.3
90
*
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
92.2
88
*
J35.2
ICD-10 Finland
Hypertrophy of adenoids
7.0
91.5
143
214
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.9
90.6
293
822
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
87.9
84
*
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
85.8
82
*
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
282.3
81.0
82
*
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
78.5
75
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
77.4
74
*
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
387.3
76.1
76
*
1450
FHL
Otomicroscopy
24.5
74.6
53
22
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
38.1
72.7
45
12
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
181.9
68.3
71
*
H04
ICPC
Ear discharge
4.6
68.2
169
387
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
3.8
67.0
219
616
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
66.9
64
*
J01DA08
ATC
[U] cefaclor
2.6
66.2
434
1828
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
65.9
63
*
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
64.8
62
*
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
5.2
64.8
136
271
R5120
NOMESCO Finland
Preparation of an aid
4.7
63.8
153
341
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
61.7
59
*
J35.8
ICD-10 Finland
Other chronic diseases of tonsils and adenoids
13.1
61.5
59
46
J01DA06
ATC
[U] cefuroxime
2.4
58.2
462
2121
H61.2
ICD-10 Finland
Impacted cerumen
3.1
57.7
256
873
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
8.8
56.5
71
82
J01DA01
ATC
[U] cefalexin
1.8
53.5
1735
12988
DCD10
NOMESCO Finland
Tympanoplasty
186.8
53.1
55
*
DFF15
NOMESCO Finland
Speech audiometry
3.5
52.9
190
568
4151
FHL
Reoperation for chronic otitis media
516.9
51.6
51
*
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
51.2
49
*
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.4
49.8
127
297
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
496.1
49.5
49
*
S02AA03
ATC
boric acid; otic
8.7
49.5
63
74
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
475.3
47.4
47
*
R01AD08
ATC
fluticasone; nasal
1.9
47.3
808
4918
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
12.2
47.1
47
39
J01MA02
ATC
ciprofloxacin; systemic
1.8
45.0
1076
7236
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.8
44.6
142
391
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
44.4
299
1265
H01
ICPC
Ear pain/earache
2.3
43.7
389
1862
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
43.6
383
1823
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
7.7
42.9
60
79
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
42.8
41
*
H92.0
ICD-10 Finland
Otalgia
2.9
42.8
212
767
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
9.9
42.8
49
50
RK520, ,
NOMESCO Finland
13.5
42.5
40
30
H60
ICD-10 Finland
Otitis externa
3.0
40.4
188
656
DEB30
NOMESCO Finland
Radical mastoidectomy
207.8
39.9
41
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.6
39.5
238
953
DAX08
NOMESCO Finland
Fitting of hearing aid
2.9
38.4
185
658
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.7
38.2
215
831
J01CA04
ATC
amoxicillin; systemic
1.9
37.6
2337
20044
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
37.6
36
*
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
187.3
35.8
37
*
J01DC02
ATC
cefuroxime; systemic
2.9
34.5
171
618
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.5
33.8
118
346
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.2
33.2
132
420
H02AB06
ATC
prednisolone; systemic
1.6
33.0
1249
9271
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
32.3
31
*
H02AB04
ATC
methylprednisolone; systemic
2.0
31.8
387
2075
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
6.8
31.4
49
73
H73.1
ICD-10 Finland
Chronic myringitis
+∞
31.3
30
*
J01FA09
ATC
clarithromycin; systemic
1.7
29.8
804
5458
H92.1
ICD-10 Finland
Otorrhoea
35.0
29.6
38
11
RK320, ,
NOMESCO Finland
6.7
28.9
46
70
J01FA10
ATC
azithromycin; systemic
1.6
28.9
1550
12336
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
28.7
291
1457
ZXA10
NOMESCO Finland
Bilateral
1.8
28.6
500
3008
J01DA09
ATC
[U] cefadroxil
1.7
28.2
697
4617
J32.4
ICD-10 Finland
Chronic pansinusitis
4.9
27.6
61
127
J01FF01
ATC
clindamycin; systemic
1.6
26.4
688
4609
J01DB01
ATC
cefalexin; oral
1.6
26.2
2239
19581
38400
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) acuta
+∞
26.1
25
*
50499
ICD-8 Finland
Deflected nasal septum
4.4
25.7
64
147
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
136.2
25.6
27
*
RK110, ,
NOMESCO Finland
6.4
25.6
42
66
R03AC02
ATC
salbutamol; inhalant
1.5
25.2
1441
11489
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
4.4
25.1
63
146
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.6
25.0
147
580
H72
ICD-10 Finland
Perforation of tympanic membrane
58.5
25.0
29
5
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
24.2
526
3350
4111
FHL
Ear canal extension
+∞
24.0
23
*
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
24.0
23
*
R03CC02
ATC
salbutamol; systemic
2.1
23.9
236
1167
H02AB07
ATC
prednisone; oral
1.9
23.9
361
2070
R03BA05
ATC
fluticasone; inhalant
1.7
23.8
489
3068
4741B
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PHARYNGICAE]
5.4
23.5
46
86
4742A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Adenoid vegetations
4.2
22.8
60
144
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
22.8
206
984
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
8.6
22.8
29
34
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.5
22.5
79
233
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
22.4
97
325
J01AA02
ATC
doxycycline; systemic
1.5
22.3
1927
16518
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.0
22.2
98
332
J01DC04
ATC
cefaclor; oral
4.5
22.2
54
122
R01AD09
ATC
mometasone; nasal
1.5
22.0
1131
8744
4143
FHL
Atticotomy or atticoanthromy through the ear canal
+∞
21.9
21
*
4146
FHL
Radical cutting (bridge broken)
+∞
21.9
21
*
H60.4
ICD-10 Finland
Cholesteatoma of external ear
20.2
21.7
32
16
ZXA00
NOMESCO Finland
Right side
1.6
21.6
658
4545
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
221.5
21.6
22
*
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
60.5
20.9
24
*
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
211.4
20.6
21
*
4221
FHL
Polyp removal from the nasal cavity, sinus puncture or irrigation, or biopsy under general anesthesia or operating room
6.4
20.5
34
54
H60.1
ICD-10 Finland
Cellulitis of external ear
4.8
20.3
46
98
J35.1
ICD-10 Finland
Hypertrophy of tonsils
3.4
20.0
71
211
R06AE07
ATC
cetirizine; oral
1.5
19.9
1124
8801
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
19.8
478
3114
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
19.8
19
*
H29
ICPC
Ear symptom/complaint other
1.8
19.5
299
1717
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
19.4
662
4679
49300
ICD-8 Finland
Asthma, bronchiale
3.3
19.3
74
231
H71
ICPC
Acute otitis media/myringitis
4.1
19.0
52
129
ZXD20
NOMESCO Finland
Day surgery
1.8
18.7
324
1929
DEB00
NOMESCO Finland
Cortical mastoidectomy
100.7
18.6
20
*
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.8
18.5
328
1967
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.3
18.4
136
597
ZXA05
NOMESCO Finland
Left side
1.5
17.6
600
4227
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
17.5
197
1021
RK420, ,
NOMESCO Finland
24.2
17.3
24
10
S02CA03
ATC
hydrocortisone and antiinfectives; otic
31.6
17.0
22
7
R03BA02
ATC
budesonide; inhalant
1.6
16.9
443
2939
H61.8
ICD-10 Finland
Other specified disorders of external ear
4.9
16.8
37
77
H70.0
ICD-10 Finland
Acute mastoiditis
+∞
16.7
16
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
16.4
350
2203
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
16.2
643
4664
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
47.8
16.0
19
*
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
3.8
15.9
48
128
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
15.8
917
7138
4741A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PALATINAE]
6.6
15.7
25
38
H73.0
ICD-10 Finland
Acute myringitis
7.2
15.7
23
32
R03BB04
ATC
tiotropium bromide; inhalant
1.8
15.6
251
1460
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.5
15.4
615
4462
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
15.4
462
3156
R03AC12
ATC
salmeterol; inhalant
2.2
15.3
123
561
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
3.5
15.3
51
146
Z97.8
ICD-10 Finland
Presence of other specified devices
7.0
15.3
23
33
J01MA12
ATC
levofloxacin; systemic
1.6
15.2
440
2982
4222
FHL
Endonasal etmoidectomy
5.6
15.1
28
50
EMB10
NOMESCO Finland
Tonsillectomy
2.0
14.9
154
774
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
+∞
14.6
14
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.4
14.5
98
414
4224
FHL
Endonasal anthrostomy
4.5
14.5
35
79
J33.8
ICD-10 Finland
Other polyp of sinus
3.0
14.4
61
203
48609
ICD-8 Finland
Pneumonia, unspecified
3.7
14.3
44
119
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
14.3
570
4129
RK120, ,
NOMESCO Finland
10.5
14.2
27
26
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
13.4
14.2
24
18
J47
ICD-10 Finland
Bronchiectasis
3.2
14.1
56
179
J20
ICD-10 Finland
Acute bronchitis
1.7
13.9
242
1442
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
13.8
624
4625
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
13.5
13
*
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
+∞
13.5
13
*
DED00
NOMESCO Finland
Obliteration of cavity after partial excision of mastoid
+∞
13.5
13
*
R03DC03
ATC
montelukast; oral
1.6
13.5
390
2637
H70
ICPC
Otitis externa
2.9
13.3
60
207
S02AA30
ATC
antiinfectives, combinations; otic
2.2
12.9
106
488
UDC10
NOMESCO Finland
Tympanoscopy
50.2
12.8
15
*
R4135
NOMESCO Finland
Rehabilitation for hearing problems
3.1
12.7
53
175
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
70.2
12.6
14
*
4129
FHL
Other measure in this category
70.2
12.6
14
*
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
4.5
12.6
30
67
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
12.5
111
527
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
12.5
227
1366
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
3.3
12.4
47
146
4452
FHL
Tonsil surgery
2.5
12.3
78
321
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
4.5
12.1
29
65
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.0
11.9
134
695
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
11.9
811
6424
H91.8
ICD-10 Finland
Other specified hearing loss
4.1
11.8
32
79
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
11.7
524
3866
R01AD05
ATC
budesonide; nasal
1.8
11.6
175
999
S01AA01
ATC
chloramphenicol; ophthalmic
2.0
11.6
118
591
R03AC03
ATC
terbutaline; inhalant
1.6
11.5
319
2133
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
11.5
133
697
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
11.5
1075
8922
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
3.6
11.4
37
104
J01FA15
ATC
telithromycin; oral
1.7
11.4
207
1247
RK290, ,
NOMESCO Finland
11.8
11.3
20
17
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
3.1
11.3
46
150
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
11.1
668
5176
T16
ICD-10 Finland
Foreign body in ear
3.7
11.1
34
92
D07AC01
ATC
betamethasone; topical
1.3
11.0
826
6628
DCA30
NOMESCO Finland
Exploration of middle ear
43.5
10.9
13
*
Z2221
NOMESCO Finland
Medical doctor
1.4
10.9
648
5012
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.4
10.7
72
305
J45
ICD-10 Finland
Asthma
1.6
10.6
234
1483
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
10.5
460
3372
H69.0
ICD-10 Finland
Patulous Eustachian tube
10.1
10.5
20
20
E000001, ,
ATC
1.4
10.4
488
3622
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
3.5
10.4
35
101
DCB00
NOMESCO Finland
Excision of lesion of middle ear
110.4
10.4
11
*
3890A
ICD-9 Finland
Deafness, Conductive deafness
110.4
10.4
11
*
4148
FHL
Radical cutting and cavity filling
+∞
10.4
10
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
10.3
458
3367
J01FA01
ATC
erythromycin; systemic
1.5
10.3
314
2146
R51.80
ICD-10 Finland
Headache
1.5
10.2
372
2634
D06AX01
ATC
fusidic acid; topical
1.6
10.2
231
1474
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
5.3
10.1
20
38
R03DA04
ATC
theophylline; systemic, rectal
1.9
9.9
130
713
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
9.8
1230
10548
Q35.1
ICD-10 Finland
Cleft hard palate
26.1
9.8
13
5
H60.0
ICD-10 Finland
Abscess of external ear
4.7
9.8
22
47
R06AX13
ATC
loratadine; oral
1.5
9.8
332
2319
H81.3
ICD-10 Finland
Other peripheral vertigo
2.5
9.7
61
251
M01AE02
ATC
naproxen; oral, rectal
1.3
9.7
1386
12085
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
55.2
9.6
11
*
L17
ICPC
Foot/toe symptom/complaint
1.3
9.6
673
5328
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.8
9.6
131
727
DPA30
NOMESCO Finland
Sphenotomy
4.8
9.5
21
44
E0000UV, ,
ATC
1.3
9.5
1011
8478
5251
FHL
Hypotension
+∞
9.4
9
*
DEB35
NOMESCO Finland
Radical mastoidectomy with tympanoplasty
+∞
9.4
9
*
4711A
ICD-9 Finland
Nasal polyps, Polypoid sinus degeneration
5.2
9.4
19
37
R74
ICPC
Upper respiratory infection acute
1.3
9.3
783
6356
L04AA01
ATC
[U] ciclosporin
3.4
9.3
32
94
R01AD11
ATC
triamcinolone; nasal
1.7
9.3
188
1166
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
9.2
424
3132
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
3.2
9.2
35
110
H02
ICPC
Hearing complaint
1.5
9.1
293
2022
50300
ICD-8 Finland
Chronic sinusitis, Maxillaris cum empyemate
5.0
9.1
19
38
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
9.0
98
504
H83.1
ICD-10 Finland
Labyrinthine fistula
36.8
9.0
11
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
8.9
640
5080
ZXE00
NOMESCO Finland
One hour or less
1.3
8.8
910
7588
N02AX02
ATC
tramadol; systemic, rectal
1.3
8.8
953
7994
R02
ICPC
Shortness of breath/dyspnoea
1.5
8.8
288
1997
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
50.1
8.7
10
*
DCA00
NOMESCO Finland
Biopsy of tympanic membrane or middle ear
50.1
8.7
10
*
M79.6
ICD-10 Finland
Pain in limb
1.3
8.7
948
7958
J02AC01
ATC
fluconazole; systemic
1.3
8.6
803
6600
R03BB01
ATC
ipratropium bromide; inhalant
2.0
8.5
94
486
H74.0
ICD-10 Finland
Tympanosclerosis
90.3
8.4
9
*
Q90.9
ICD-10 Finland
Down syndrome, unspecified
90.3
8.4
9
*
ZZG00
NOMESCO Finland
Graft of cartilage
12.8
8.4
14
11
1451
FHL
Otomicroscopy and paper place
+∞
8.3
8
*
H74.4
ICD-10 Finland
Polyp of middle ear
+∞
8.3
8
*
R4110
NOMESCO Finland
Physiotherapy
1.3
8.3
612
4869
R42
ICD-10 Finland
Dizziness and giddiness
1.4
8.3
496
3826
46401
ICD-8 Finland
Acute laryngitis and tracheitis, Laryngitis acuta (subglottica)
4.1
8.2
22
54
J01FA06
ATC
roxithromycin; oral
1.3
8.2
873
7288
R06AX27
ATC
desloratadine; oral
1.3
8.2
658
5292
R01AD12
ATC
fluticasone furoate; nasal
1.3
8.2
709
5762
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
8.2
661
5323
ZXC10
NOMESCO Finland
Use of laser
2.4
8.1
52
216
XG410
NOMESCO Finland
Flow-volume spirometry
1.9
8.1
95
502
Z3226
NOMESCO Finland
Physiotherapist
1.4
8.1
418
3147
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
8.1
309
2208
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
8.1
443
3370
X58
ICD-10 Finland
Exposure to other specified factors
1.4
8.0
330
2390
Z2446
NOMESCO Finland
Social worker
1.6
8.0
170
1069
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
7.9
975
8282
R03AC13
ATC
formoterol; inhalant
1.8
7.9
108
600
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.5
7.9
232
1571
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
7.9
486
3763
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.8
7.8
120
691
H68.0
ICD-10 Finland
Eustachian salpingitis
10.8
7.8
14
13
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
7.8
1790
16318
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.7
1452
12933
H62.2*B44.8
ICD-10 Finland
Otitis externa in aspergillosis
45.1
7.7
9
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
7.7
318
2303
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
7.6
137
825
RK530, ,
NOMESCO Finland
18.4
7.6
11
6
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
18.4
7.6
11
6
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.5
7.6
218
1471
49099
ICD-8 Finland
Bronchitis, unspecified
3.3
7.5
27
82
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.5
1004
8600
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.8
7.5
100
552
XF400
NOMESCO Finland
ECG with 12 standard connections
1.4
7.4
365
2725
Q89.34
ICD-10 Finland
Cartagena syndrome (immotile cilia)
80.3
7.4
8
*
R06AE09
ATC
levocetirizine; oral
1.4
7.4
323
2363
J45.8
ICD-10 Finland
Mixed asthma
2.1
7.4
67
324
DHA10
NOMESCO Finland
Biopsy of cavity of nose
3.7
7.3
22
59
J46
ICD-10 Finland
Status asthmaticus
2.2
7.3
61
285
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
7.3
779
6491
N02BE01
ATC
paracetamol; systemic, rectal
1.3
7.3
2239
21024
DHB20
NOMESCO Finland
Polypectomy of internal nose
2.7
7.3
38
143
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
7.3
297
2145
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
7.3
7
*
4119
FHL
Other measure in this category
+∞
7.3
7
*
H70.9
ICD-10 Finland
Mastoiditis, unspecified
+∞
7.3
7
*
D07AC13
ATC
mometasone; topical
1.3
7.2
627
5095
H27
ICPC
Fear of ear disease
2.7
7.1
37
139
J37.0
ICD-10 Finland
Chronic laryngitis
2.0
7.1
70
350
J01.1
ICD-10 Finland
Acute frontal sinusitis
2.6
7.0
40
158
49302
ICD-8 Finland
Asthma, Rhinitis allergica cum asthmate bronchiali
3.9
7.0
20
52
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
2.8
7.0
34
124
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
1.9
6.9
83
443
J01EB05
ATC
sulfafurazole; systemic
7.5
6.9
15
20
A01AB09
ATC
miconazole; local oral
1.5
6.9
185
1231
N07CA01
ATC
betahistine; oral
1.6
6.9
149
943
UDM02
NOMESCO Finland
Sinoscopy
2.3
6.8
48
209
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
3.4
6.8
24
72
Z02.7
ICD-10 Finland
Issue of medical certificate
1.6
6.8
157
1008
B01AB05
ATC
enoxaparin; parenteral
1.3
6.8
659
5422
WX002
NOMESCO Finland
Sedation and analgesia
1.3
6.8
410
3162
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.8
1486
13383
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
6.1
6.8
17
28
38408
ICD-8 Finland
Other inflammatory diseases of ear, Alii definiti
40.1
6.8
8
*
R01BA01
ATC
phenylpropanolamine; oral
1.8
6.8
100
571
A46
ICD-10 Finland
Erysipelas
1.4
6.7
302
2219
Z98.8
ICD-10 Finland
Other specified postsurgical states
2.7
6.7
33
121
D01AC02
ATC
miconazole; topical
1.6
6.7
163
1061
S02CA01
ATC
prednisolone and antiinfectives; otic
22.6
6.7
9
*
SPAT1044
SPAT
Tympanometry
2.2
6.7
52
237
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.4
6.6
247
1758
S06.0
ICD-10 Finland
Concussion
1.4
6.6
258
1852
D07AB08
ATC
desonide; topical
1.4
6.5
240
1701
7806A
ICD-9 Finland
General symptoms, Pyrexia of unknown origin
3.4
6.5
23
69
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
6.5
838
7126
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
2.9
6.5
29
101
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
6.5
789
6666
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.3
6.4
740
6207
A02BC02
ATC
pantoprazole; systemic
1.2
6.4
1552
14079
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
7.4
6.4
14
19
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.7
6.3
101
590
J06.80
ICD-10 Finland
Continuously repeating infections of a child
9.3
6.3
12
13
W19
ICD-10 Finland
Unspecified fall
1.5
6.3
221
1555
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
2.1
6.3
53
250
H60.2
ICD-10 Finland
Malignant otitis externa
18.0
6.3
9
5
DCB10
NOMESCO Finland
Freeing of adhesions of middle ear
+∞
6.2
6
*
38410, ,
ICD-8 Finland
+∞
6.2
6
*
3829X
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified otitis media
+∞
6.2
6
*
3858X
ICD-9 Finland
Other disorders of middle ear and mastoid
+∞
6.2
6
*
38200
ICD-8 Finland
Acute / Acute otitis media with mastoiditis
+∞
6.2
6
*
0419X
ICD-9 Finland
Bacterial infection in conditions classified elsewhere and of unspecified site, Bacterial infection, unspecified
+∞
6.2
6
*
N05BB01
ATC
hydroxyzine; systemic
1.6
6.2
139
886
C03CA01
ATC
furosemide; systemic
1.3
6.2
656
5443
H74
ICPC
Chronic otitis media
26.7
6.2
8
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
6.2
697
5827
G40.9
ICD-10 Finland
Epilepsy, unspecified
1.9
6.2
78
424
F83
ICD-10 Finland
Mixed specific developmental disorders
3.1
6.2
25
82
RK220, ,
NOMESCO Finland
4.0
6.2
17
43
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
6.1
348
2657
J35.0
ICD-10 Finland
Chronic tonsillitis
1.7
6.1
115
703
E9509
ICD-8 Finland
Suicide and self-inflicted poisoning by solid or liquid substances, Other and unspecified solid and liquid substances
4.1
6.1
16
39
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.4
6.1
244
1760
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
3.2
6.0
23
73

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
619
2581
2.78
99.38
2.7
1.7
—
—
—
0
0
465
2470
2.05
39.74
1.8
1.4
—
—
—
0
0
497
3087
1.74
25.18
2.2
2.0
—
—
—
0
0
1237
10277
1.36
13.87
7.0
6.1
0.66
0.66
%
0.14
1145
9611
1273
10626
1.35
13.82
6.9
6.0
2.91
2.84
%
0.52
1185
9943
1277
10688
1.35
13.52
7.1
6.3
8.57
8.58
%
0.03
1188
10027
1311
11029
1.35
13.36
6.9
6.1
28.61
28.31
%
0.41
1224
10378
1291
10839
1.35
13.32
6.7
5.9
56.27
56.79
%
0.80
1205
10184
368
2498
1.54
12.48
4.0
4.3
31.89
32.39
%
0.38
253
1711
1360
11644
1.32
11.69
6.8
6.1
0.20
0.19
e9/l
1.55
1164
10221
1249
10569
1.32
11.67
7.1
6.4
—
—
—
0
0
1342
11591
1.30
10.33
6.6
5.9
2.11
1.96
e9/l
0.96
1167
10264
1307
11253
1.30
10.29
6.6
5.9
0.04
0.04
e9/l
1.68
1114
9738
1303
11238
1.29
10.03
6.6
5.9
0.61
0.58
e9/l
2.80
1114
9728
155
897
1.77
9.86
2.3
1.4
5.97
17.76
u/ml
—
9
25
1032
8718
1.29
9.07
2.0
2.0
94.59
95.53
pmol/l
0.25
548
4590
297
2079
1.48
8.62
3.9
4.2
—
—
—
0
0
1789
16217
1.27
8.62
4.3
4.0
12.41
11.71
mm/h
1.24
1636
14984
213
1390
1.57
8.57
1.5
1.3
473.04
250.40
u/ml
0.79
202
1278
49
200
2.47
7.98
1.8
1.3
2.92
2.85
g/l
0.10
38
140
49
200
2.47
7.98
1.8
1.3
0.34
0.39
g/l
0.77
38
140
49
200
2.47
7.98
1.8
1.3
6.14
6.94
g/l
1.19
38
139
49
201
2.46
7.90
1.8
1.3
—
—
—
0
0
1818
16621
1.25
7.62
7.7
7.3
79.04
79.59
u/l
0.18
1701
15661
49
209
2.37
7.28
2.5
2.4
1.40
1.26
e9/l
0.44
44
183
519
4132
1.31
6.88
4.3
3.7
297.52
439.75
ng/l
0.57
399
3151
1435
12866
1.23
6.85
5.4
4.8
6.73
6.67
mmol/l
0.45
1328
11975
1112
9725
1.23
6.68
6.9
6.2
1.21
1.21
mmol/l
0.67
987
8863
1124
9848
1.23
6.62
15.9
15.2
1.25
1.27
inr
0.23
295
2923
153
988
1.58
6.50
5.1
5.0
24.59
24.63
mmol/l
0.05
142
932
211
1464
1.48
6.42
1.5
1.4
—
—
—
0
0
1439
12970
1.22
6.32
9.3
8.9
4.13
4.11
e9/l
0.08
1228
11311
568
4639
1.28
6.14
1.5
1.5
2.45
2.35
g/l
0.55
319
2824
712
5989
1.25
5.99
4.4
4.2
—
—
—
0
0
233
1674
1.43
5.92
2.8
2.7
10.21
10.56
g/l
0.51
217
1517
1205
10723
1.21
5.87
7.6
6.7
1.21
1.21
mmol/l
0.59
1039
9114
23
75
3.08
5.76
2.2
2.5
384.29
304.72
e6/l
0.22
14
36
695
5856
1.25
5.73
3.6
3.2
1651.95
1546.03
ng/l
0.26
585
4992
1245
11133
1.21
5.72
6.1
6.0
11.18
12.06
umol/l
1.64
1165
10529
64
338
1.91
5.59
1.9
1.7
0.71
0.79
g/l
0.25
48
263
2370
22614
1.27
5.55
16.1
13.7
23.25
24.10
mg/l
0.58
1912
17693
1671
15387
1.20
5.54
4.8
4.2
—
—
—
0
0
1057
9329
1.21
5.51
5.0
4.9
35.67
35.67
g/l
0.00
972
8658
657
5541
1.24
5.32
4.1
4.1
89.30
88.52
%
0.32
640
5404
211
1520
1.42
5.30
4.9
4.4
5.18
5.14
kpa
0.31
201
1444
36
156
2.32
5.25
2.6
2.5
0.22
0.21
e9/l
0.11
31
131
187
1322
1.44
5.21
1.6
1.9
1.33
1.41
g/l
0.21
170
1214
208
1502
1.41
5.16
5.0
4.4
7.41
7.40
ph
0.19
17
176
363
2865
1.31
5.08
1.3
1.3
588.27
525.60
titre
0.20
75
579
634
5364
1.23
4.95
2.9
2.7
2350.81
5723.20
umol/l
1.87
542
4705
36
161
2.25
4.91
2.6
2.5
606.90
561.44
e6/l
0.18
31
132
1593
14697
1.19
4.86
3.1
3.1
49.15
46.50
u/l
0.49
1486
13743
959
8468
1.20
4.82
2.0
2.1
—
—
—
0
0
161
1126
1.45
4.77
5.2
4.7
—
—
—
0
0
138
1982
0.68
4.66
4.9
3.8
—
—
—
0
0
36
165
2.20
4.65
3.6
3.0
26.77
27.41
mu/l
0.03
36
153
100
638
1.59
4.57
3.3
3.3
—
—
—
0
0
217
1614
1.37
4.55
4.3
4.1
101.70
87.34
ng/l
0.61
190
1404
773
6722
1.20
4.54
2.6
2.5
57.10
70.44
u/l
0.55
715
6207
653
7563
0.82
4.53
2.7
2.7
—
—
—
0
0
195
1430
1.39
4.46
3.0
2.8
5.08
5.19
e9/l
0.04
146
1170
628
5362
1.22
4.44
2.3
2.3
—
—
—
0
0
797
6991
1.19
4.21
2.4
2.4
—
—
—
0
0
38
187
2.05
4.13
2.7
2.4
40.09
36.87
%
0.56
38
187
365
2961
1.27
4.12
7.0
6.0
1.08
1.07
mmol/l
0.50
338
2743
1001
8972
1.18
4.09
2.4
2.3
75.60
75.88
nmol/l
0.11
883
8068
80
499
1.62
4.05
1.8
1.6
20465.21
12248.16
e6/l
0.38
56
364
38
192
1.99
3.87
1.5
1.3
193675.64
100256.50
e6/l
0.30
22
133
25
107
2.35
3.82
1.7
1.5
1.38
1.19
nmol/l
0.33
18
85
2042
19423
1.18
3.75
5.8
5.4
39.73
39.48
mmol/mol
0.59
1878
17972
154
1122
1.39
3.71
9.2
9.5
24.38
24.32
mmol/l
0.07
147
1087
720
6322
1.18
3.70
2.1
2.1
217.94
243.12
u/l
0.28
663
5942
177
1327
1.36
3.58
3.7
3.3
4.46
4.54
pmol/l
0.48
147
1182
579
5023
1.19
3.39
1.6
1.5
18.97
20.22
nmol/l
1.26
490
4294
665
5848
1.18
3.32
2.4
2.2
2.80
2.91
mg/l
0.61
551
4964
100
689
1.47
3.30
6.3
7.0
1.57
1.32
mmol/l
0.74
90
596
19
77
2.48
3.29
1.9
2.2
—
—
—
0
0
28
135
2.08
3.27
3.6
3.8
—
—
—
0
0
20
85
2.36
3.15
1.1
1.0
9.33
19.10
u/ml
—
10
53
415
3523
1.21
3.08
1.3
1.2
24.93
32.72
iu/ml
1.23
120
1082
380
3204
1.21
3.02
2.7
2.4
2.34
2.34
g/l
0.04
349
2959
294
2415
1.24
3.01
7.8
7.6
5.16
5.09
kpa
0.57
278
2293
294
2416
1.24
3.00
7.8
7.6
11.64
12.36
kpa
1.37
278
2297
150
1132
1.34
2.96
9.8
10.7
—
—
—
0
0
293
2413
1.24
2.93
7.8
7.6
0.93
1.10
mmol/l
0.27
229
1881
39
221
1.77
2.89
3.3
3.4
—
—
—
0
0
1565
14737
1.14
2.88
4.7
4.4
571.21
1652.64
e6/l
1.05
19
206
416
3558
1.20
2.85
2.8
3.0
2.98
2.40
e6/l
0.56
223
1966
224
1797
1.27
2.83
4.1
3.1
190.98
214.15
ng/l
0.45
200
1631
89
620
1.45
2.82
1.4
1.6
0.23
0.23
g/l
0.17
84
587
59
378
1.57
2.78
1.7
1.5
—
—
—
0
0
795
7177
1.15
2.76
3.3
3.3
2.35
2.35
mmol/l
0.23
690
6316
20
92
2.18
2.66
1.1
1.0
13.75
10.57
u/ml
—
5
16
341
2883
1.21
2.65
1.3
1.2
—
—
—
0
0
36
206
1.76
2.61
2.4
2.3
2.89
1.66
g/24h
0.29
15
105
744
6715
1.15
2.57
3.6
3.3
7.51
7.77
mmol/l
0.82
615
5720
90
641
1.42
2.56
1.4
1.6
1.19
1.17
g/l
0.18
85
608
232
1892
1.25
2.56
1.2
1.2
—
—
—
0
0
403
3474
1.19
2.54
2.7
2.4
12.75
13.17
umol/l
0.55
377
3233
435
3775
1.18
2.53
2.7
2.8
1.04
1.34
e6/l
0.76
241
2174
666
5973
1.15
2.52
4.1
3.8
—
—
—
0
0
29
157
1.86
2.52
1.2
2.3
7.65
6.83
mmol/l
0.38
22
109
631
5644
1.15
2.48
7.0
6.8
—
—
—
0
0
689
6203
1.15
2.46
4.0
3.9
11.78
9.06
mg/mmol
0.64
436
3993
350
2992
1.19
2.43
2.9
2.5
22.23
22.88
%
0.34
288
2552
241
1990
1.23
2.39
9.7
7.7
10.38
9.48
mmol/l
1.17
232
1903
595
5315
1.15
2.38
1.4
1.3
2.27
1.68
u/ml
0.41
125
1363
532
4732
1.15
2.25
2.5
1.8
1.14
1.31
mg/l
0.65
393
3541
384
3333
1.18
2.24
1.3
1.2
12.56
11.25
u/ml
0.13
122
1280
256
2143
1.21
2.24
8.5
8.1
95.38
95.62
%
0.25
241
2055
40
248
1.62
2.21
3.1
3.8
—
—
—
0
0
173
1391
1.26
2.20
5.1
5.2
—
—
—
0
0
68
475
1.44
2.20
7.5
8.6
12.21
11.23
mmol/l
1.16
61
420
12
48
2.51
2.18
1.2
1.1
—
—
—
0
0
68
476
1.44
2.17
7.5
8.5
105.92
105.33
mmol/l
0.55
61
421
103
776
1.34
2.14
1.3
1.2
0.18
0.97
u/ml
—
6
62
235
1966
1.21
2.08
9.0
8.5
121.54
121.70
g/l
0.04
226
1903
138
1734
0.79
2.07
4.6
3.6
1.22
1.23
mmol/l
0.64
118
1483
42
269
1.57
2.06
2.6
2.7
—
—
—
0
0
385
3367
1.17
2.05
2.3
2.4
30.03
29.98
s
0.06
371
3256
399
3502
1.16
2.03
4.3
3.5
0.81
0.82
mmol/l
0.95
367
3282
1771
16986
1.11
2.00
4.0
3.9
14.71
14.74
pmol/l
0.25
1572
15365
31
185
1.68
2.00
1.7
1.5
1.37
1.26
promille
0.13
25
142
38
240
1.59
1.98
1.6
1.6
63.48
61.59
%
0.11
25
155
45
297
1.52
1.95
1.5
1.6
—
—
—
0
0
40
257
1.56
1.95
1.3
1.3
—
—
—
0
0
777
7145
1.12
1.94
3.5
3.2
31.72
33.08
u/l
0.44
737
6778
2102
20371
1.12
1.90
4.8
4.6
2.45
1.97
mu/l
0.39
1905
18686
235
1986
1.20
1.89
10.1
8.2
—
—
—
0
0
43
284
1.52
1.87
6.9
6.9
10.66
11.73
mg/l
0.57
38
261
533
5891
0.88
1.86
4.2
3.9
0.00
0.00
estimate
1.08
143
2045
682
6253
1.12
1.79
4.2
3.9
7.40
7.40
ph
0.12
92
1200
46
312
1.48
1.78
1.3
1.4
18.50
20.43
u/l
0.18
36
264
644
5889
1.12
1.77
3.5
3.3
550.17
319.01
mg/l
0.51
429
3854
265
2283
1.18
1.73
1.8
1.7
—
—
—
0
0
22
126
1.75
1.67
1.5
1.4
15.85
24.47
umol/l
0.95
22
119
75
563
1.34
1.66
1.2
1.4
—
—
—
0
0
125
1005
1.25
1.66
1.8
1.8
1.50
1.48
g/l
0.08
109
876
2086
20268
1.11
1.63
3.9
3.7
1.32
1.28
mmol/l
1.68
1899
18576
1099
10370
1.10
1.62
2.7
2.6
—
—
—
0
0
46
320
1.44
1.59
3.0
2.5
—
—
—
0
0
239
2060
1.17
1.57
2.1
2.4
0.22
0.21
g/l
0.43
225
1921
24
144
1.67
1.57
2.1
3.2
—
—
—
0
0
855
7984
1.10
1.57
3.9
3.6
127.14
54.76
ng/l
0.44
531
5372
5
15
3.34
1.52
9.4
4.8
—
—
—
0
0
51
367
1.40
1.49
1.1
1.1
50.60
1373.77
iu/ml
—
10
99
551
5044
1.11
1.49
3.6
3.6
—
—
—
0
0
2312
22617
1.11
1.48
18.3
15.8
139.61
139.58
mmol/l
0.21
2243
21984
2209
21568
1.10
1.44
4.7
4.5
2.68
2.73
mmol/l
1.58
2022
19906
557
6052
0.90
1.44
3.3
3.2
—
—
—
0
0
73
942
0.77
1.43
1.5
1.6
261.25
305.69
mu/l
1.68
68
856
2131
20774
1.10
1.43
4.4
4.2
5.93
5.88
mmol/l
0.78
1934
18894
26
164
1.59
1.43
2.9
2.3
—
—
—
0
0
80
622
1.29
1.42
1.4
1.4
274.19
290.02
ug/g
0.29
45
346
48
345
1.40
1.42
1.1
1.1
4.76
8.00
u/ml
0.73
20
150
248
2164
1.16
1.42
1.5
1.4
—
—
—
0
0
2316
22672
1.11
1.42
18.5
15.9
3.97
3.96
mmol/l
0.09
2236
21996
25
157
1.60
1.40
1.1
1.1
0.27
1.99
u/ml
—
10
53
12
60
2.00
1.38
2.2
1.6
—
—
—
0
0
442
4021
1.12
1.34
1.8
1.7
1132.03
1159.32
nmol/l
0.25
321
3012
27
175
1.55
1.34
3.0
3.3
21.33
33.35
mg/l
0.43
18
135
67
516
1.31
1.30
1.6
1.9
4.37
5.08
iu/l
0.28
22
185
70
543
1.30
1.29
1.3
1.2
8.69
15.90
u/ml
—
7
96
2151
21014
1.09
1.28
4.3
4.1
1.39
1.44
mmol/l
6.26
1965
19399
69
535
1.30
1.28
1.2
1.2
7.96
3.94
u/ml
—
7
55
19
114
1.67
1.28
2.2
2.4
7.43
7.42
ph
—
8
35
605
6507
0.91
1.27
1.5
1.5
—
—
—
0
0
51
380
1.35
1.25
1.1
1.1
5.81
4.69
u/ml
0.12
25
192
281
2500
1.14
1.25
3.0
2.8
7.73
8.40
umol/l
0.27
239
2156
20
124
1.62
1.20
1.1
1.1
1.07
1.05
ratio
—
5
48
25
164
1.53
1.20
1.2
1.2
9.78
4.16
u/ml
—
8
56
24
156
1.54
1.20
1.1
1.1
—
—
—
0
0
6
26
2.31
1.18
2.0
5.8
—
—
—
0
0
835
7881
1.08
1.18
4.0
3.7
58.89
101.24
e6/l
1.58
594
5588
44
324
1.36
1.17
1.5
1.3
—
—
—
0
0
27
390
0.69
1.13
1.1
1.1
—
—
—
0
0
7
30
2.34
1.12
1.0
1.0
—
—
—
0
0
8
40
2.00
1.12
1.5
1.3
—
—
—
0
0
38
515
0.73
1.10
1.5
1.4
—
—
—
0
0
33
456
0.72
1.09
4.2
3.1
1.60
1.60
mmol/l
0.01
33
441
8
41
1.95
1.08
1.9
1.7
—
—
—
0
0
152
1309
1.17
1.08
7.3
7.3
24.25
24.51
mmol/l
0.32
143
1235
38
512
0.74
1.07
1.5
1.4
—
—
—
0
0
7
33
2.12
1.05
3.4
1.7
92.96
25.04
pmol/l
—
7
28
45
341
1.32
1.03
1.7
1.4
—
—
—
0
0
17
106
1.61
1.02
2.8
2.8
—
—
—
0
0
714
6736
1.08
1.01
3.4
3.3
39.95
79.13
e6/l
1.84
550
5213
715
6747
1.08
1.01
3.3
3.1
—
—
—
0
0
29
205
1.42
1.00
3.1
2.7
—
—
—
0
0
9
48
1.88
1.00
1.6
1.9
—
—
—
0
0
245
2197
1.13
1.00
5.9
4.2
1.75
1.83
mmol/l
0.13
203
1805
7
35
2.00
1.00
1.0
1.1
—
—
—
0
0
40
527
0.76
0.99
1.6
1.5
—
—
—
0
0
24
164
1.47
0.99
1.3
1.3
1.95
4.33
u/ml
0.79
14
96
111
940
1.19
0.99
1.3
1.3
—
—
—
0
0
44
335
1.32
0.98
1.2
1.5
—
—
—
0
0
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
2161
21198
1.08
0.97
4.3
4.1
4.50
4.60
mmol/l
4.48
1987
19672
81
667
1.22
0.97
8.4
5.8
1.52
1.43
mg/l
0.43
76
615
297
2702
1.11
0.95
1.2
1.3
—
—
—
0
0
7
37
1.89
0.94
1.7
1.5
—
—
—
0
0
6
118
0.51
0.94
2.5
1.8
—
—
—
0
0
28
384
0.73
0.91
1.1
1.1
—
—
—
0
0
41
529
0.77
0.89
4.0
4.5
—
—
—
0
0
515
4826
1.08
0.88
3.8
4.0
1.02
1.02
kg/l
0.58
97
725
67
548
1.23
0.87
1.1
1.1
0.94
3.07
u/ml
1.98
35
305
61
494
1.24
0.87
2.3
2.1
127.85
130.19
g/l
0.29
41
366
32
425
0.75
0.86
4.3
3.2
7.16
7.63
mmol/l
0.41
32
412
251
2757
0.90
0.85
1.6
1.7
—
—
—
0
0
197
1765
1.12
0.85
1.4
1.4
—
—
—
0
0
115
993
1.16
0.84
1.2
1.1
—
1.82
—
0
12
2404
23717
1.08
0.83
11.1
9.8
26.53
26.34
u/l
0.16
2312
22852
34
257
1.33
0.83
1.3
1.3
—
43.30
—
0
11
355
3822
0.92
0.80
3.0
3.0
0.96
0.76
ug/l
0.95
247
2502
58
474
1.23
0.78
1.1
1.1
1.14
2.37
u/ml
1.03
25
264
638
6054
1.07
0.78
3.3
3.1
—
—
—
0
0
80
676
1.19
0.77
1.3
1.1
—
—
—
0
0
13
198
0.65
0.76
1.0
1.2
—
—
—
0
0
89
1036
0.85
0.75
1.4
1.5
18.33
22.00
iu/l
0.58
72
856
251
2300
1.10
0.74
1.3
1.3
—
—
—
0
0
41
325
1.26
0.73
1.1
1.1
—
—
—
0
0
5
25
2.00
0.72
1.4
2.0
62.40
43.36
umol/l
—
5
25
231
2111
1.10
0.72
2.2
2.2
372.42
370.13
nmol/l
0.06
211
1932
10
60
1.67
0.72
1.6
1.9
—
—
—
0
0
11
68
1.62
0.71
1.8
1.8
—
—
—
0
0
7
40
1.75
0.71
1.0
1.2
—
—
—
0
0
315
2924
1.09
0.70
1.6
1.6
—
—
—
0
0
181
1636
1.11
0.70
4.2
3.9
0.50
0.73
%
1.46
68
523
45
363
1.24
0.70
3.8
5.2
401.01
367.18
umol/l
1.01
38
321
497
4696
1.07
0.70
2.7
2.6
5.61
6.00
e6/l
0.21
447
4228
20
143
1.40
0.70
1.2
1.1
—
—
—
0
0
93
806
1.16
0.69
1.1
1.1
—
—
—
0
0
7
43
1.63
0.66
7.0
4.7
66.93
33.72
g/mol
—
7
35
240
2209
1.09
0.66
6.0
4.2
5.91
5.82
kpa
0.55
235
2145
227
2087
1.09
0.64
2.3
2.4
28.42
38.75
u/l
3.12
194
1784
5
29
1.72
0.64
3.8
8.4
—
—
—
0
0
27
347
0.78
0.62
1.6
1.5
0.24
0.37
nmol/l
1.83
21
287
99
1121
0.88
0.61
1.8
1.6
—
—
—
0
0
92
806
1.15
0.61
1.6
1.7
—
—
—
0
0
158
1433
1.11
0.60
3.2
2.9
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
2.80
—
0
13
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
2556
25340
1.07
0.59
23.2
20.0
40.25
40.56
%
0.51
2404
23727
39
476
0.82
0.59
3.4
2.3
16.75
16.24
%
0.40
24
232
14
97
1.44
0.58
3.7
3.0
—
—
—
0
0
2559
25373
1.07
0.58
23.0
19.9
7.04
6.80
e9/l
2.80
2484
24601
1934
19632
0.95
0.58
19.5
16.3
15.05
14.86
%
0.31
1899
19248
413
3907
1.07
0.58
2.8
3.0
2.45
2.45
mmol/l
0.16
363
3421
40
327
1.23
0.58
1.1
1.1
0.03
0.43
u/ml
2.88
11
108
15
106
1.42
0.57
1.3
3.1
172.63
141.42
umol/l
—
8
60
195
1793
1.09
0.57
4.5
4.0
0.89
0.93
%
0.09
79
599
197
1813
1.09
0.57
2.2
2.4
6.93
6.93
ug/l
0.00
168
1601
2558
25367
1.07
0.57
22.9
19.8
30.14
30.18
pg
0.46
2521
24969
51
429
1.19
0.56
1.3
1.2
93.10
39.55
u/ml
—
7
36
275
2568
1.08
0.56
2.8
2.7
1.75
1.75
%
0.01
229
2267
60
513
1.17
0.56
1.6
1.5
—
—
—
0
0
60
513
1.17
0.56
1.1
1.2
—
—
—
0
0
2558
25370
1.07
0.55
23.0
19.9
4.51
4.52
e12/l
0.23
2485
24607
1045
10151
1.05
0.55
3.2
2.8
117.17
116.07
ug/l
0.05
959
9391
27
212
1.28
0.55
1.1
1.1
—
—
—
0
0
312
2931
1.07
0.55
2.3
2.5
174.13
128.91
ug/g
0.96
246
2320
18
133
1.36
0.55
1.0
1.0
—
—
—
0
0
143
1299
1.11
0.54
1.3
1.3
21.36
52.50
au/ml
—
5
72
2555
25343
1.07
0.54
23.0
19.9
252.91
250.69
e9/l
0.98
2494
24642
11
159
0.69
0.54
1.0
1.1
—
—
—
0
0
2557
25365
1.07
0.53
22.9
19.8
90.46
90.47
fl
0.02
2522
24970
17
125
1.36
0.53
1.1
1.3
1.51
1.52
g/l
0.06
17
125
2373
23489
1.06
0.53
14.7
12.8
—
—
—
0
0
9
62
1.45
0.53
1.4
2.5
—
—
—
0
0
15
108
1.39
0.53
4.2
3.0
788.80
1258.51
u/ml
0.79
15
108
9
63
1.43
0.52
1.3
1.4
4.01
3.43
mmol/l
—
9
57
2558
25380
1.07
0.52
23.1
20.0
135.20
135.51
g/l
0.50
2522
24986
38
314
1.21
0.51
1.2
1.2
3.00
5.03
u/ml
0.55
15
138
124
1367
0.90
0.51
1.3
1.4
—
—
—
0
0
31
251
1.24
0.51
1.6
2.2
—
—
—
0
0
200
1854
1.08
0.50
2.8
2.7
73.09
69.58
e9/l
0.50
145
1395
55
472
1.17
0.50
5.9
3.7
—
—
—
0
0
97
1082
0.89
0.50
3.9
3.5
—
—
—
0
0
912
8851
1.04
0.50
3.3
3.3
5.70
5.94
ph
1.28
70
658
14
190
0.74
0.49
1.4
1.2
—
—
—
0
0
156
1433
1.09
0.49
2.5
2.4
24.04
24.93
au/ml
0.05
14
119
19
145
1.31
0.48
1.7
1.5
105.32
81.79
umol/l
1.08
19
145
7
46
1.52
0.48
1.0
1.2
2.14
6.83
u/ml
—
7
37
11
76
1.45
0.48
1.2
1.3
—
—
—
0
0
641
6179
1.05
0.48
3.5
3.2
0.29
0.45
e6/l
2.16
490
4744
204
2188
0.93
0.47
1.3
1.3
—
—
—
0
0
36
299
1.21
0.47
1.4
1.6
—
—
—
0
0
10
68
1.47
0.47
2.3
2.9
—
—
—
0
0
37
440
0.84
0.46
1.5
1.3
—
—
—
0
0
24
191
1.26
0.46
4.6
4.6
13.29
11.14
%
1.38
24
191
43
365
1.18
0.46
4.6
3.2
—
—
—
0
0
11
77
1.43
0.45
3.8
4.5
—
—
—
0
0
41
347
1.18
0.45
1.2
1.2
90.44
45.21
u/l
0.36
35
299
94
846
1.11
0.45
6.5
5.9
0.93
0.89
%
0.56
87
784
190
1770
1.08
0.44
1.9
2.2
12.09
12.64
nmol/l
0.39
162
1597
88
791
1.12
0.43
1.3
1.3
200.79
225.45
miu/ml
0.29
29
369
183
1704
1.08
0.43
4.7
4.1
0.07
0.10
%
0.39
67
511
113
1030
1.10
0.43
4.4
3.0
1.51
1.22
%
1.67
113
1022
48
414
1.16
0.43
1.1
1.1
—
—
—
0
0
20
157
1.28
0.43
1.6
1.6
—
—
—
0
0
96
868
1.11
0.43
1.2
1.2
—
—
—
0
0
9
131
0.69
0.43
1.3
1.2
—
—
—
0
0
61
537
1.14
0.42
1.3
1.3
203.81
234.79
u/ml
0.59
37
309
48
415
1.16
0.42
1.1
1.1
—
—
—
0
0
163
1752
0.93
0.42
3.4
3.4
—
—
—
0
0
49
425
1.16
0.41
1.2
1.6
—
—
—
0
0
21
167
1.26
0.41
1.0
1.2
0.90
2.85
u/ml
—
8
74
51
444
1.15
0.41
3.3
3.3
4.14
4.13
e9/l
0.02
51
444
70
784
0.89
0.41
1.4
1.6
10.27
8.20
u/l
0.51
57
621
95
861
1.11
0.41
2.9
2.6
21.21
21.66
s
0.54
85
766
0
15
0.00
0.41
0.0
1.5
—
1.44
—
0
9
52
454
1.15
0.41
1.6
2.2
0.96
0.77
nmol/l
1.10
45
382
30
250
1.20
0.40
1.4
1.3
—
—
—
0
0
56
493
1.14
0.39
2.7
2.3
52.77
92.79
ug/min
0.94
29
306
9
66
1.36
0.38
1.0
1.2
—
—
—
0
0
52
458
1.14
0.37
4.0
3.6
59.02
57.57
%
0.43
52
458
39
336
1.16
0.37
1.2
1.1
4.28
2.29
u/ml
—
10
156
22
268
0.82
0.37
3.0
2.5
3.95
4.06
mmol/l
1.03
22
263
22
268
0.82
0.37
3.0
2.5
106.36
105.21
mmol/l
0.65
22
263
9
69
1.30
0.37
1.4
1.7
40.33
110.41
nmol/24h
—
9
69
55
487
1.13
0.36
1.4
1.8
—
—
—
0
0
9
70
1.29
0.36
1.0
1.1
—
—
—
0
0
49
431
1.14
0.36
2.2
3.3
0.81
0.82
nmol/l
0.06
34
333
12
90
1.33
0.35
1.2
1.4
—
—
—
0
0
19
153
1.24
0.35
1.6
1.4
13.00
13.85
u/l
0.26
19
144
6
43
1.40
0.35
3.5
7.7
—
—
—
0
0
93
852
1.09
0.35
6.5
5.9
1.90
1.63
%
1.18
86
789
6
44
1.36
0.34
1.2
1.7
—
—
—
0
0
6
44
1.36
0.34
1.5
1.5
—
—
—
0
0
147
1378
1.07
0.32
1.2
1.2
—
—
—
0
0
195
1846
1.06
0.32
1.5
1.4
—
—
—
0
0
117
1088
1.08
0.32
2.7
2.4
—
—
—
0
0
103
953
1.08
0.32
2.2
2.0
—
—
—
0
0
11
83
1.33
0.32
1.1
1.2
0.92
8.96
u/ml
—
6
63
1462
14817
0.97
0.31
3.8
3.7
—
—
—
0
0
53
474
1.12
0.31
1.6
1.5
107.99
106.11
u/ml
—
10
83
179
1692
1.06
0.31
1.9
2.6
66.90
66.48
g/l
0.29
163
1541
19
156
1.22
0.31
1.1
1.2
—
—
—
0
0
40
352
1.14
0.30
1.2
1.2
—
—
—
0
0
70
638
1.10
0.30
1.2
1.1
17.45
4.62
u/ml
—
6
79
91
841
1.08
0.30
2.2
1.9
1.41
1.75
ug/l
0.17
77
737
22
260
0.84
0.29
3.0
2.5
—
—
—
0
0
26
222
1.17
0.29
1.4
1.5
—
—
—
0
0
63
573
1.10
0.29
4.8
3.4
—
—
—
0
0
170
1610
1.06
0.29
4.7
4.1
0.08
0.50
%
0.84
49
421
7
57
1.23
0.29
3.1
2.5
1.44
1.87
mmol/l
—
7
44
79
727
1.09
0.29
2.2
3.4
1427.41
5432.07
u/ml
0.50
70
620
17
205
0.83
0.28
1.5
1.4
6.94
8.33
mmol/l
1.28
17
200
107
1000
1.07
0.27
4.4
3.0
0.64
0.64
%
0.01
107
993
13
104
1.25
0.26
24.5
4.9
61.13
72.94
mg/l
—
8
78
13
104
1.25
0.26
1.2
1.2
—
—
—
0
0
38
338
1.13
0.26
2.4
2.4
13.34
8.91
umol/l
0.18
25
257
75
693
1.08
0.26
1.1
1.2
—
—
—
0
0
96
897
1.07
0.25
4.8
3.3
—
—
—
0
0
9
73
1.23
0.25
1.0
1.0
6.28
8.41
mu/l
—
9
62
9
74
1.22
0.25
1.2
1.1
—
—
—
0
0
124
1171
1.06
0.24
1.2
1.1
113.88
145.93
titre
—
8
28
88
823
1.07
0.23
3.0
2.6
—
—
—
0
0
50
456
1.10
0.23
1.2
1.3
—
—
—
0
0
32
359
0.89
0.23
1.4
1.6
—
—
—
0
0
62
572
1.09
0.23
2.5
2.2
10.69
11.30
mg/l
0.15
55
531
5
41
1.22
0.22
2.0
1.3
—
—
—
0
0
5
41
1.22
0.22
1.2
1.0
—
—
—
0
0
53
487
1.09
0.22
1.1
1.1
0.47
1.71
u/ml
1.62
21
232
523
5345
0.97
0.21
1.7
1.6
1.36
1.36
mmol/l
0.05
440
4522
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
0.80
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.06
—
0
10
0
11
0.00
0.21
0.0
1.1
—
5.08
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
0.02
—
0
6
0
13
0.00
0.21
0.0
1.2
—
15.87
—
0
8
52
479
1.09
0.20
2.9
2.9
34.33
33.79
umol/l
0.07
45
435
46
501
0.92
0.20
1.1
1.1
—
—
—
0
0
62
576
1.08
0.20
3.4
2.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
40.75
—
0
8
29
259
1.12
0.20
3.1
2.9
18.40
20.41
nmol/l
0.61
29
246
55
509
1.08
0.20
1.1
1.1
3.75
6.54
u/ml
0.84
28
287
17
146
1.16
0.19
1.1
1.2
—
—
—
0
0
10
122
0.82
0.19
1.2
1.2
—
—
—
0
0
11
90
1.22
0.19
1.3
1.1
—
—
—
0
0
23
203
1.13
0.19
1.2
1.0
—
—
—
0
0
1972
19590
1.02
0.18
20.6
17.4
332.51
332.98
g/l
1.34
1961
19406
29
261
1.11
0.18
1.1
1.3
—
—
—
0
0
460
4504
1.02
0.18
3.1
2.9
553.76
547.66
mosm/kgh2o
0.23
390
3879
12
100
1.20
0.18
1.1
1.1
1502.17
1555.63
miu/ml
0.05
12
100
134
1284
1.05
0.18
1.2
1.2
—
—
—
0
0
57
610
0.93
0.18
5.3
4.1
7.41
7.42
ph
0.39
50
543
44
406
1.08
0.17
3.2
3.5
2360.76
981.61
u/ml
0.31
38
380
12
101
1.19
0.16
2.5
2.5
1791.67
1993.33
ml
0.34
12
90
678
6678
1.02
0.16
4.7
4.9
2.89
3.75
ug/l
0.44
585
5962
11
92
1.20
0.16
2.5
1.7
—
—
—
0
0
23
206
1.12
0.16
1.2
2.1
—
—
—
0
0
44
472
0.93
0.15
1.5
1.8
205.38
203.81
pmol/l
0.02
39
450
48
513
0.93
0.15
5.5
4.4
2.14
2.51
mmol/l
0.42
36
336
114
1094
1.04
0.15
2.6
2.3
2192.33
5384.99
u/l
1.63
49
398
27
296
0.91
0.15
4.6
1.9
—
—
—
0
0
53
498
1.07
0.14
3.0
3.4
30.20
27.23
mg/l
0.17
29
319
16
141
1.14
0.13
1.1
1.0
—
—
—
0
0
14
122
1.15
0.13
1.2
1.6
—
—
—
0
0
24
218
1.10
0.13
1.1
1.1
—
—
—
0
0
1077
10863
0.99
0.13
5.0
4.9
0.00
0.00
estimate
0.50
152
2124
11
94
1.17
0.13
1.0
1.0
—
—
—
0
0
37
395
0.94
0.12
1.1
1.2
—
—
—
0
0
1081
10893
0.99
0.12
3.7
3.6
0.00
0.00
estimate
1.23
159
2231
10
116
0.86
0.12
6.6
6.8
—
—
—
0
0
189
1843
1.03
0.12
5.6
3.7
5.09
4.70
kpa
1.42
184
1789
57
599
0.95
0.11
1.4
1.6
564.94
490.71
mg/l
0.33
52
561
446
4522
0.98
0.11
1.7
1.7
14731289.79
25578117.46
pmol/l
0.29
353
3765
81
842
0.96
0.11
5.1
4.3
—
—
—
0
0
152
1560
0.97
0.11
1.3
1.2
168.41
138.80
iu/ml
0.42
63
590
507
5007
1.01
0.10
1.8
2.0
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
45
1.11
0.09
1.6
1.8
2.40
4.80
nmol/l
—
5
45
12
106
1.13
0.09
1.2
1.3
—
—
—
0
0
86
833
1.03
0.08
1.0
1.1
—
—
—
0
0
275
2707
1.02
0.08
1.6
1.5
—
—
—
0
0
12
107
1.12
0.08
1.1
1.1
422.58
207.73
iu/ml
0.60
12
107
60
623
0.96
0.08
1.6
3.4
1.26
1.71
ratio
—
7
49
5
60
0.83
0.08
1.0
2.2
—
—
—
0
0
28
263
1.06
0.08
1.3
1.2
—
—
—
0
0
5
63
0.79
0.08
1.0
2.1
—
—
—
0
0
13
117
1.11
0.08
1.2
1.3
—
—
—
0
0
13
117
1.11
0.08
1.2
1.3
—
71.43
—
0
14
45
470
0.96
0.08
1.7
3.6
—
—
—
0
0
6
71
0.84
0.07
1.0
1.2
—
—
—
0
0
78
757
1.03
0.07
2.4
2.3
1408.09
506.88
ug/l
0.41
72
708
16
147
1.09
0.07
1.2
1.0
—
—
—
0
0
7
81
0.86
0.07
1.0
1.1
—
—
—
0
0
7
83
0.84
0.07
1.0
1.0
—
—
—
0
0
7
84
0.83
0.07
1.0
1.2
—
0.10
—
0
8
20
214
0.93
0.07
1.4
1.2
—
—
—
0
0
9
88
1.02
0.07
1.3
1.2
—
—
—
0
0
8
93
0.86
0.06
1.0
1.1
—
—
—
0
0
12
132
0.91
0.06
1.5
1.7
—
—
—
0
0
43
413
1.04
0.06
3.9
2.7
—
—
—
0
0
30
285
1.05
0.06
1.2
1.3
0.59
0.63
nmol/l
0.30
30
272
9
100
0.90
0.06
2.3
2.0
—
—
—
0
0
9
104
0.86
0.06
5.3
5.5
—
—
—
0
0
9
104
0.86
0.06
2.7
2.8
—
—
—
0
0
51
493
1.03
0.06
5.4
3.7
—
—
—
0
0
17
158
1.08
0.06
1.1
1.3
32.65
35.92
mmol/l
0.27
17
143
141
1387
1.02
0.05
1.6
2.4
—
—
—
0
0
11
100
1.10
0.05
1.3
1.3
—
—
—
0
0
1094
10972
0.99
0.04
3.8
3.6
0.00
0.01
estimate
1.32
143
2066
204
2018
1.01
0.04
3.7
4.2
15.99
17.31
ug/l
0.06
153
1649
83
814
1.02
0.04
3.2
3.3
0.26
0.29
g/l
0.24
34
354
18
170
1.06
0.04
1.1
1.3
166.74
181.37
pmol/l
0.22
18
170
38
368
1.03
0.04
1.5
1.2
—
—
—
0
0
19
180
1.06
0.04
1.5
1.4
36.31
29.81
%
0.31
13
111
12
111
1.08
0.04
4.3
1.3
181.08
350.05
u/l
0.78
12
100
130
1316
0.99
0.03
2.3
2.3
—
—
—
0
0
10
108
0.93
0.03
1.0
1.3
145.90
138.52
nmol/l
—
10
108
34
330
1.03
0.03
2.2
1.8
4.56
4.83
mmol/24h
0.21
34
286
37
360
1.03
0.02
1.6
1.6
—
—
—
0
0
19
198
0.96
0.02
1.5
1.6
7.63
7.52
mmol/l
0.09
19
191
133
1341
0.99
0.02
3.5
2.4
—
—
—
0
0
25
258
0.97
0.02
1.6
1.5
289.00
281.73
mosm/kgh2o
0.71
16
187
27
262
1.03
0.02
1.6
1.4
1263.42
1678.96
e6/l
0.58
19
189
27
262
1.03
0.02
1.7
1.7
—
—
—
0
0
29
282
1.03
0.02
2.6
2.5
—
—
—
0
0
999
10003
1.00
0.01
9.9
9.3
0.00
0.00
e9/l
0.00
790
8133
66
668
0.99
0.01
14.1
10.1
—
—
—
0
0
397
3980
1.00
0.01
1.6
1.6
—
—
—
0
0
133
1338
0.99
0.01
3.5
2.2
—
—
—
0
0
105
1043
1.01
0.00
3.8
2.5
—
—
—
0
0
21
204
1.03
0.00
1.8
1.4
—
—
—
0
0
125
1244
1.00
0.00
3.6
2.4
—
—
—
0
0
16
157
1.02
0.00
17.8
13.6
705.75
788.85
nmol/l
0.30
16
151
40
401
1.00
0.00
1.4
1.4
62.68
65.11
mmol/l
0.12
31
325
75
745
1.01
0.00
1.5
2.4
9.93
10.31
g/l
0.45
68
667
16
159
1.01
0.00
1.3
1.4
—
—
—
0
0
11
106
1.04
0.00
1.2
1.2
—
—
—
0
0
62
623
0.99
0.00
1.4
2.3
37.96
37.61
g/l
0.16
54
547
23
234
0.98
0.00
1.7
1.4
20107.82
87479.82
e6/l
1.34
11
134
22
219
1.00
0.00
1.5
1.4
—
—
—
0
0
64
642
1.00
0.00
1.7
3.4
34.92
80.96
mg/l
1.34
50
527
25
252
0.99
0.00
1.2
1.3
—
—
nmol/l
—
0
0
53
534
0.99
0.00
1.5
1.7
50.02
14.87
e6/l
0.37
40
417
53
534
0.99
0.00
1.5
1.8
1343.44
915.76
e6/l
0.23
41
434
24
244
0.98
0.00
1.6
1.9
—
—
—
0
0
64
640
1.00
0.00
1.7
3.4
40.86
59.98
mg/l
1.06
50
524
10
96
1.04
0.00
5.0
12.1
—
—
—
0
0
22
225
0.98
0.00
1.2
1.1
—
—
—
0
0
133
1328
1.00
0.00
3.5
2.4
—
—
—
0
0
6
60
1.00
0.00
1.0
1.0
3.17
3.32
kpa
—
6
49
6
60
1.00
0.00
1.0
1.0
6.80
6.91
kpa
—
6
49
6
60
1.00
0.00
1.0
1.0
—
—
—
0
0
6
60
1.00
0.00
1.0
1.0
—
0.48
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
53
0.94
-0.00
2.2
2.3
17.04
16.27
umol/l
—
5
53
9
95
0.95
-0.00
1.4
1.3
151.22
166.44
mmol/24h
—
9
95
5
59
0.85
-0.00
1.2
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
100.40
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
1044.00
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.14
—
0
5
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1745.20
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
1.50
—
0
5
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_CHRON_SUPOTITIS and mortality.

Females

Parameter HR [95% CI] p-value
H8_CHRON_SUPOTITIS 1.218 [1.07, 1.39] 0.003
Birth year 0.994 [0.99, 1.0] 0.171

During the follow-up period (1.1.1998 — 31.12.2019), 566 out of 6742 females with H8_CHRON_SUPOTITIS died.

Males

Parameter HR [95% CI] p-value
H8_CHRON_SUPOTITIS 1.217 [1.06, 1.4] 0.006
Birth year 0.985 [0.98, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 673 out of 8885 males with H8_CHRON_SUPOTITIS died.

Mortality risk

Mortality risk for people of age

years, who have H8_CHRON_SUPOTITIS.

N-year risk Females Males
1 0.116% 0.167%
5 0.661% 1.295%
10 1.752% 3.212%
15 3.385% 6.503%
20 6.301% 10.844%

Relationships between endpoints

Index endpoint: H8_CHRON_SUPOTITIS – Chronic suppurative otitis media

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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