Other and unspecified nail disorders

L12_NAILNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L60.8, L60.9
  • Hospital discharge: ICD-9 7038E|7038G|7038X|7039
  • Hospital discharge: ICD-8 70301|7030[8-9]
  • Cause of death: ICD-10 L60.8, L60.9
  • Cause of death: ICD-9 7038E|7038G|7038X|7039
  • Cause of death: ICD-8 70301|7030[8-9]

2 out of 7 registries used, show all original rules.

834

4. Check minimum number of events

None

834

5. Include endpoints

None

834

6. Filter based on genotype QC (FinnGen only)

806

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4733 2702 2009
Only index persons 4307 2489 1818
Unadjusted period prevalence (%)
Whole population 0.07 0.08 0.06
Only index persons 0.08 0.09 0.07
Median age at first event (years)
Whole population 51.51 52.58 50.15
Only index persons 52.27 53.11 51.12

-FinnGen-

Key figures

All Female Male
Number of individuals 806 531 275
Unadjusted period prevalence (%) 0.17 0.19 0.13
Median age at first event (years) 58.75 57.76 60.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
834
Matched controls
8340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L60.9
ICD-10 Finland
Nail disorder, unspecified
349.2
307.7
550
46
L60.8
ICD-10 Finland
Other nail disorders
143.6
307.7
303
33
RJ411, ,
NOMESCO Finland
55.5
100.0
57
11
L60.0
ICD-10 Finland
Ingrowing nail
7.4
67.3
104
157
S22
ICPC
Nail symptom/complaint
5.4
59.9
131
278
B35.1
ICD-10 Finland
Tinea unguium
5.4
58.6
128
271
RJ410, ,
NOMESCO Finland
109.6
56.6
61
6
RJ421, ,
NOMESCO Finland
126.8
55.6
59
5
RJ190, ,
NOMESCO Finland
289.1
53.8
54
*
XQ848
NOMESCO Finland
Dermatological photography
8.7
51.0
67
83
TQW80
NOMESCO Finland
Local dermatologic skincare
8.7
46.7
61
75
RJ422, ,
NOMESCO Finland
472.5
45.7
45
*
QDH00
NOMESCO Finland
Avulsion of toe nail
64.9
42.7
49
8
L60.1
ICD-10 Finland
Onycholysis
14.1
41.9
39
29
L03.0
ICD-10 Finland
Cellulitis of finger and toe
4.1
41.7
128
353
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.8
36.7
126
375
L84
ICD-10 Finland
Corns and callosities
5.7
34.3
66
123
E0000UV, ,
ATC
2.4
33.7
417
2448
D01AE16
ATC
amorolfine; topical
3.2
33.2
155
559
D01BA02
ATC
terbinafine; oral
2.6
33.2
276
1350
XQ845
NOMESCO Finland
Dermatoscopy
9.7
32.9
39
42
127
Kela drug reimbursment
Transplant complication
11.0
30.6
33
31
Z3229
NOMESCO Finland
Other healthcare associate professional
3.6
29.0
107
332
L04AA06
ATC
mycophenolic acid; systemic
8.5
27.5
36
44
RJ511, ,
NOMESCO Finland
144.7
26.8
28
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.8
26.2
42
65
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.7
25.8
87
254
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.4
25.4
210
1008
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.5
24.9
203
967
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.9
23.9
33
43
QDH01
NOMESCO Finland
Excision of nail bed in toe
89.4
23.8
26
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.2
23.8
50
101
D07AC01
ATC
betamethasone; topical
2.0
20.7
327
2011
D07AD01
ATC
clobetasol; topical
2.4
20.5
171
817
L04AD01
ATC
ciclosporin; systemic
7.4
20.5
30
42
A46
ICD-10 Finland
Erysipelas
2.5
20.2
141
620
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.8
20.1
32
49
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.0
20.1
59
156
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
6.5
18.9
31
49
A10AB05
ATC
insulin aspart; parenteral
3.0
18.9
87
308
L60.3
ICD-10 Finland
Nail dystrophy
28.6
18.8
25
9
SPAT1260
SPAT
Consultation of another employee
2.2
18.0
171
859
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.8
17.9
41
89
RJ420, ,
NOMESCO Finland
23.4
17.8
25
11
J01DB01
ATC
cefalexin; oral
2.4
17.7
715
5966
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
17.2
126
565
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
22.4
16.9
24
11
S18
ICPC
Laceration/cut
1.8
16.2
396
2752
SPAT1153
SPAT
Removal of sutures
1.9
16.2
279
1737
ZXC50
NOMESCO Finland
Cryotherapy
4.5
16.0
39
89
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
15.9
56
168
TK800
NOMESCO Finland
Hemodialysis
6.0
15.8
28
48
A10AB01
ATC
insulin (human); parenteral
3.8
15.5
48
132
Z94.0
ICD-10 Finland
Kidney transplant status
15.1
15.4
25
17
L04AX03
ATC
methotrexate; systemic
2.5
15.3
103
443
A11CC03
ATC
alfacalcidol; systemic
5.5
15.0
29
54
J01FF01
ATC
clindamycin; systemic
1.9
15.0
240
1451
NHQ40
NOMESCO Finland
Amputation of toe
6.9
14.9
23
34
J02AC02
ATC
itraconazole; systemic
2.1
14.8
167
893
L17
ICPC
Foot/toe symptom/complaint
1.9
14.8
262
1637
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.9
14.6
73
270
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.0
14.4
66
232
SPAT1263
SPAT
Sampling
1.8
14.4
364
2530
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.0
14.3
200
1153
J01MA02
ATC
ciprofloxacin; systemic
1.8
14.1
320
2151
RJ414, ,
NOMESCO Finland
30.6
13.9
18
6
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
13.9
105
476
RJ210, ,
NOMESCO Finland
54.3
13.8
16
*
A10AE05
ATC
insulin detemir; parenteral
3.0
13.8
64
227
L57.0
ICD-10 Finland
Actinic keratosis
2.4
13.6
95
416
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
13.5
168
928
V03AE01
ATC
polystyrene sulfonate; oral
13.1
13.5
23
18
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
13.3
143
749
UJF32
NOMESCO Finland
Coloscopy
1.9
13.2
221
1348
A10AC01
ATC
insulin (human); parenteral
2.6
13.2
79
321
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
13.1
285
1884
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
13.0
223
1370
RD211, ,
NOMESCO Finland
3.2
13.0
51
164
N03AX16
ATC
[U] pregabalin
1.9
12.9
205
1228
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.5
12.9
45
134
J02AC01
ATC
fluconazole; systemic
1.7
12.9
346
2425
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.6
12.8
78
320
C03CA01
ATC
furosemide; systemic
1.9
12.7
219
1346
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
12.7
129
660
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.2
12.6
119
591
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
12.6
311
2126
A10AA02, ,
ATC
3.7
12.6
40
112
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
24.7
12.5
17
7
S94
ICPC
Ingrowing nail
4.9
12.4
27
56
L04AD02
ATC
tacrolimus; systemic
11.9
12.4
22
19
S97
ICPC
Chronic ulcer skin
2.9
12.3
60
219
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.0
12.2
26
53
N30.0
ICD-10 Finland
Acute cystitis
2.0
12.1
145
789
Z00.0
ICD-10 Finland
General medical examination
1.9
11.9
178
1043
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
11.9
198
1201
SPAT1310
SPAT
Counselling related to known health issue
1.7
11.9
273
1823
H02AB06
ATC
prednisolone; systemic
1.7
11.8
388
2850
SPAT1301
SPAT
No procedures
1.7
11.8
264
1749
N18.8
ICD-10 Finland
Other chronic renal failure
5.2
11.8
24
47
TQW99
NOMESCO Finland
Other minor procedure on skin
3.0
11.8
53
185
A02BC02
ATC
pantoprazole; systemic
1.7
11.7
555
4485
S29
ICPC
Skin symptom/complaint other
1.9
11.6
165
950
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
11.6
83
366
Z49.1
ICD-10 Finland
Extracorporeal dialysis
10.2
11.5
22
22
SPAT1262
SPAT
Handing over of treatment supplies
2.0
11.4
147
820
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
11.4
100
483
A10AE04
ATC
insulin glargine; parenteral
2.3
11.3
90
416
WZC30
NOMESCO Finland
Teaching
2.0
11.3
138
755
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
12.9
11.2
19
15
Z3231
NOMESCO Finland
Registered nurse
1.8
11.1
227
1463
RS221, ,
NOMESCO Finland
5.8
11.0
20
35
H04AA01
ATC
glucagon; nasal, parenteral
4.1
11.0
30
75
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
10.9
160
931
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.9
10.8
32
85
L60
ICD-10 Finland
Nail disorders
10.8
10.8
20
19
RJ425, ,
NOMESCO Finland
60.8
10.6
12
*
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.3
10.6
88
414
L28
ICPC
Limited function/disability (L)
1.9
10.6
140
785
Z49.2
ICD-10 Finland
Other dialysis
14.4
10.5
17
12
SPAT1255
SPAT
Intravenous administration of medicine
2.6
10.5
61
244
RJ521, ,
NOMESCO Finland
111.4
10.4
11
*
L40.8
ICD-10 Finland
Other psoriasis
12.2
10.4
18
15
RJ412, ,
NOMESCO Finland
33.0
10.3
13
*
V03AE02
ATC
sevelamer; oral
33.0
10.3
13
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.0
10.3
47
165
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.1
10.2
98
490
E000001, ,
ATC
1.8
10.1
166
1000
D07AB02
ATC
hydrocortisone butyrate; topical
1.7
10.0
250
1693
L04AX01
ATC
azathioprine; systemic
3.2
10.0
40
130
D05AX52
ATC
calcipotriol, combinations; topical
2.8
10.0
51
191
B35.3
ICD-10 Finland
Tinea pedis
3.1
10.0
42
141
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
9.8
359
2671
CKC12
NOMESCO Finland
Photocoagulation of retina
3.0
9.8
44
153
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.2
9.8
86
414
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
4.8
9.8
22
47
S76
ICPC
Skin infection other
2.7
9.8
51
193
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.5
9.7
62
260
E87.5
ICD-10 Finland
Hyperkalaemia
4.9
9.6
21
44
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.8
9.6
48
178
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
9.5
54
214
RJ520, ,
NOMESCO Finland
+∞
9.4
9
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
9.4
236
1598
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
22.0
9.4
13
6
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
9.4
195
1255
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
9.4
152
910
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.9
9.3
141
825
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
8.8
9.3
19
22
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.0
9.3
112
608
R50.9
ICD-10 Finland
Fever, unspecified
1.9
9.3
128
727
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
9.3
251
1730
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
13.9
9.2
15
11
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.0
9.2
40
137
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
9.1
52
206
SPAT1229
SPAT
Assessment of need for aid
2.4
9.1
64
280
J01EA01
ATC
trimethoprim; systemic
1.7
9.1
215
1430
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
9.1
111
605
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.9
9.1
20
42
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
9.1
323
2377
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.6
9.1
53
213
K65.0
ICD-10 Finland
Acute peritonitis
10.2
9.0
17
17
S09
ICPC
Infected finger/toe
3.2
9.0
36
117
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
9.0
157
959
H13
ICPC
Plugged feeling ear
1.8
9.0
151
912
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
9.0
339
2529
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
8.9
97
507
H25.8
ICD-10 Finland
Other senile cataract
2.2
8.9
78
375
D05BB02
ATC
acitretin; oral
4.0
8.9
25
64
A10AB04
ATC
insulin lispro; parenteral
3.1
8.9
36
118
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.7
8.9
28
78
R4180
NOMESCO Finland
Podiatric therapy
5.0
8.9
19
39
H3603, E103,
ICD-10 Finland
9.6
8.8
17
18
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.3
8.8
64
285
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.5
8.8
57
241
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.6
8.7
50
199
QCH00
NOMESCO Finland
Avulsion of finger nail
50.5
8.7
10
*
D02AE01
ATC
carbamide; topical
2.4
8.6
60
262
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
8.6
101
543
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
8.6
229
1568
XCK10
NOMESCO Finland
Photography of fundus of eye
2.1
8.6
82
409
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
9.1
8.6
17
19
137
Kela drug reimbursment
Uraemia requiring dialysis
10.2
8.5
16
16
N18.0
ICD-10 Finland
End-stage renal disease
10.2
8.5
16
16
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
8.5
290
2106
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
20.3
8.5
12
6
S21
ICPC
Skin texture symptom/complaint
1.9
8.5
118
672
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.8
8.4
135
803
RD210, ,
NOMESCO Finland
4.4
8.4
21
49
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.7
8.4
44
167
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.7
8.4
45
173
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
3.8
8.4
25
67
L40.5
ICD-10 Finland
Arthropathic psoriasis
4.7
8.4
19
41
L60.5
ICD-10 Finland
Yellow nail syndrome
+∞
8.3
8
*
70309
ICD-8 Finland
Diseases of nail, Unspecified
+∞
8.3
8
*
D01AE15
ATC
terbinafine; topical
2.3
8.3
61
273
A10AA01, ,
ATC
3.3
8.3
31
97
L04AA01
ATC
[U] ciclosporin
7.2
8.3
19
27
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.6
8.2
49
199
Z71.8
ICD-10 Finland
Other specified counselling
1.6
8.2
253
1793
Z00.8
ICD-10 Finland
Other general examinations
2.2
8.1
72
349
B05DA
ATC
Isotonic solutions
11.8
8.1
14
12
QDH05
NOMESCO Finland
Correction of deformity of toe nail
33.7
8.1
10
*
XCH00
NOMESCO Finland
Eye pressure measurement
2.7
8.1
42
159
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
9.0
8.1
16
18
SPAT1312
SPAT
General health counselling
1.6
8.0
254
1808
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
22.3
8.0
11
5
D07AB08
ATC
desonide; topical
2.0
8.0
92
491
J01FA10
ATC
azithromycin; systemic
1.5
8.0
474
3870
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
8.0
194
1296
H02AB04
ATC
methylprednisolone; systemic
1.8
8.0
116
670
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
7.9
209
1425
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
7.8
342
2612
A12AA04
ATC
calcium carbonate; oral
6.0
7.7
20
34
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.1
7.7
31
102
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.2
7.7
63
296
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
7.6
97
536
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
8.1
7.6
16
20
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.4
7.6
54
238
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
7.6
83
435
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.9
7.6
22
58
N02BE01
ATC
paracetamol; systemic, rectal
1.8
7.6
728
6600
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.1
7.5
31
103
A06AD11
ATC
lactulose; oral
1.9
7.5
106
606
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.8
7.5
36
131
M25.5
ICD-10 Finland
Pain in joint
1.5
7.5
261
1896
D09AB01
ATC
zinc bandage without supplements; topical
4.5
7.5
18
41
U04
ICPC
Incontinence urine
2.5
7.5
45
184
K59.09
ICD-10 Finland
Constipation, unspecified
2.3
7.4
57
260
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
13.5
7.4
12
9
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
2.3
7.4
53
235
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.6
7.4
43
173
Z49.0
ICD-10 Finland
Preparatory care for dialysis
8.5
7.3
15
18
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
7.3
59
275
70308
ICD-8 Finland
Diseases of nail, Alii definiti
+∞
7.3
7
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
3.0
7.3
31
105
XCD20
NOMESCO Finland
Photoangiography of eye
4.5
7.2
17
38
A02BC01
ATC
omeprazole; systemic
1.6
7.2
210
1464
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
7.1
54
245
L30.3
ICD-10 Finland
Infective dermatitis
2.8
7.1
35
129
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.1
7.1
29
96
M79.6
ICD-10 Finland
Pain in limb
1.5
7.1
334
2578
D05AX02
ATC
calcipotriol; topical
2.9
7.1
33
118
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
7.1
98
557
B05DB
ATC
Hypertonic solutions
10.1
7.0
13
13
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.3
7.0
18
43
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.4
7.0
25
76
C07AB07
ATC
bisoprolol; oral
1.5
7.0
352
2752
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
4.4
7.0
17
39
SPAT1081
SPAT
Cardiorespiratory global assessment
2.4
7.0
45
190
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
6.9
81
435
H3601, E103,
ICD-10 Finland
7.6
6.9
15
20
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.9
6.9
32
114
SPAT1325
SPAT
Vaccination
1.5
6.9
254
1861
J01DA09
ATC
[U] cefadroxil
1.6
6.9
210
1476
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.4
6.9
24
72
C02AC05
ATC
moxonidine; oral
2.6
6.9
38
149
E000006, ,
ATC
2.1
6.9
61
296
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.2
6.8
58
276
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.2
6.8
18
44
R05
ICD-10 Finland
Cough
1.6
6.8
165
1097
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.8
239
1732
L71.9
ICD-10 Finland
Rosacea, unspecified
4.3
6.8
17
40
B35.6
ICD-10 Finland
Tinea inguinalis [Tinea cruris]
4.3
6.8
17
40
T89
ICPC
Diabetes insulin dependent
2.6
6.8
39
156
RS340, ,
NOMESCO Finland
40.4
6.8
8
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
16.8
6.8
10
6
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
3.4
6.7
23
68
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
3.4
6.7
23
68
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
7.3
6.7
15
21
A10AE06
ATC
insulin degludec; parenteral
2.7
6.7
35
133
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.1
6.7
65
326
R06AE07
ATC
cetirizine; oral
1.5
6.7
349
2740
A02BC03
ATC
lansoprazole; oral
1.5
6.7
220
1571
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
22.7
6.7
9
*
B07.9
ICD-10 Finland
Verruca simplex
2.8
6.7
33
122
SPAT1211
SPAT
Application of soft bandage
2.0
6.7
72
376
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
6.7
81
441
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
6.6
219
1565
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
12.4
6.6
11
9
TK820
NOMESCO Finland
Peritoneal dialysis
12.4
6.6
11
9
SBB10
NOMESCO Finland
Dental impressions
2.1
6.6
62
308
M13.9
ICD-10 Finland
Arthritis, unspecified
2.1
6.6
64
322
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
6.5
79
429
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
6.5
121
750
SPAT1216
SPAT
Assessment of functional ability
1.7
6.5
114
695
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
3.7
6.5
20
55
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
5.8
6.5
17
30
SPAT1252
SPAT
Overall medication plan or its review
2.1
6.4
58
284
C05AA08
ATC
fluocortolone; rectal, topical
1.8
6.4
108
652
J01AA02
ATC
doxycycline; systemic
1.5
6.4
610
5364
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.6
6.4
144
940
M05BA04
ATC
alendronic acid; oral
2.0
6.4
64
326
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.6
6.4
37
149
L72.1
ICD-10 Finland
Trichilemmal cyst
2.4
6.3
42
180
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
6.3
187
1302
E10
ICD-10 Finland
Type 1 diabetes mellitus
3.5
6.3
21
61
M05BX04
ATC
denosumab; parenteral
2.3
6.3
47
212
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.3
6.3
23
71
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
6.3
91
524
D07AC13
ATC
mometasone; topical
1.5
6.3
221
1598
K07
ICPC
Swollen ankles/oedema
2.5
6.3
38
156
J01DA01
ATC
[U] cefalexin
1.4
6.2
485
4087
C03DA01
ATC
spironolactone; oral
1.8
6.2
87
496
U01
ICPC
Dysuria/painful urination
2.0
6.2
65
336
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.0
6.2
65
337
D07XC01
ATC
betamethasone; topical
1.8
6.1
91
528
L01BA01
ATC
methotrexate; systemic
2.7
6.1
32
122
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.3
6.1
47
215
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
6.1
110
676
H26.4
ICD-10 Finland
After-cataract
2.0
6.1
68
360
PHM99
NOMESCO Finland
Endovenous obliteration of other vein
3.2
6.1
23
73
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
6.0
170
1169
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.8
6.0
102
615
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
10.1
6.0
11
11
B37.2
ICD-10 Finland
Candidiasis of skin and nail
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
279
808
4.69
89.93
1.9
1.4
—
—
—
0
0
171
748
2.62
25.15
2.4
1.5
—
—
—
0
0
493
3398
2.10
23.69
8.6
5.6
0.57
0.57
e9/l
0.12
429
2951
503
3501
2.10
23.44
8.6
5.6
1.83
1.95
e9/l
1.70
447
3118
505
3525
2.10
23.29
8.8
5.9
0.18
0.19
e9/l
0.11
443
3121
492
3406
2.08
23.15
8.7
5.6
0.04
0.04
e9/l
1.00
431
2960
468
3203
2.05
22.45
9.5
6.2
—
—
—
0
0
418
2786
2.00
21.16
6.5
4.5
35.77
35.86
g/l
0.13
395
2611
541
3955
2.05
20.98
12.0
8.8
3.98
4.04
e9/l
0.26
486
3469
664
5264
2.28
20.52
10.5
7.1
76.91
77.67
u/l
0.22
634
4936
341
2152
1.99
19.83
3.6
2.4
53.57
61.90
u/l
1.93
317
1982
416
2819
1.95
19.56
2.8
2.2
76.00
76.02
nmol/l
0.01
385
2531
490
3524
1.95
19.13
7.1
6.0
9.84
11.01
umol/l
2.83
467
3342
271
1621
2.00
18.02
1.4
1.2
1.07
1.92
u/ml
1.12
96
432
401
2753
1.88
17.48
2.3
2.1
—
—
—
0
0
459
3318
1.85
16.71
8.9
5.9
28.13
28.51
%
0.32
432
3118
435
3094
1.85
16.67
8.9
5.8
0.69
0.68
%
0.14
407
2884
448
3226
1.84
16.40
9.1
6.1
8.59
8.42
%
0.60
422
3023
453
3274
1.84
16.37
8.7
5.6
56.85
56.74
%
0.07
425
3073
177
938
2.13
16.17
1.5
1.3
523.43
505.53
titre
0.04
35
199
445
3208
1.83
16.13
8.9
5.8
2.76
2.82
%
0.22
417
2999
72
258
2.96
15.24
1.1
1.2
—
—
—
0
0
444
3253
1.78
14.74
11.4
6.3
1.22
1.22
mmol/l
0.22
388
2765
113
523
2.34
14.27
16.8
6.3
10.49
9.05
mmol/l
1.36
108
498
568
4499
1.82
14.22
6.0
4.2
403.00
2189.54
e6/l
—
8
69
623
5083
1.89
14.11
5.7
4.0
11.80
11.72
mm/h
0.05
590
4695
117
560
2.27
13.64
5.0
4.4
0.94
1.15
%
0.37
39
200
206
1222
1.91
13.47
1.4
1.3
31.40
31.60
iu/ml
0.01
52
410
107
499
2.31
13.25
5.2
4.6
0.03
0.14
%
0.75
30
140
109
513
2.29
13.21
5.1
4.3
0.81
0.73
%
0.11
34
172
355
2493
1.74
13.21
3.7
3.4
824.90
54.63
ng/l
0.48
243
1652
200
1185
1.90
13.08
1.4
1.3
16.71
12.86
u/ml
0.27
87
452
252
1613
1.81
12.85
2.9
2.1
2.90
2.95
mg/l
0.17
231
1377
108
513
2.27
12.80
5.5
3.2
—
—
—
0
0
402
2959
1.69
12.32
14.3
12.6
1.21
1.21
inr
0.01
136
903
22
38
5.92
12.31
3.3
1.5
9.42
9.63
mmol/l
0.09
22
38
109
528
2.22
12.31
5.1
4.5
0.29
0.11
%
0.69
31
166
156
868
1.98
12.21
2.4
2.2
139.69
119.83
ug/g
0.17
128
682
580
4729
1.74
11.98
6.0
4.1
—
—
—
0
0
446
3391
1.68
11.96
5.0
3.4
0.00
0.00
estimate
0.50
114
683
256
1680
1.76
11.83
4.7
4.1
—
—
—
0
0
161
919
1.93
11.66
2.8
1.9
—
—
—
0
0
774
6961
2.56
11.66
20.3
12.7
21.23
22.34
mg/l
0.43
657
5446
273
1838
1.72
11.45
5.6
3.7
0.00
0.01
estimate
0.88
104
634
146
820
1.95
11.06
10.4
4.8
1.13
1.04
mmol/l
1.95
138
765
224
1446
1.75
10.82
1.4
1.4
2.10
2.36
g/l
1.80
155
899
296
2062
1.68
10.81
4.0
2.9
—
—
—
0
0
639
5427
1.76
10.62
5.1
4.0
14.75
14.69
pmol/l
0.23
593
4948
251
1683
1.70
10.53
4.4
2.5
336.86
5642.85
umol/l
5.85
221
1486
318
2275
1.64
10.37
4.1
3.3
2.34
2.36
mmol/l
1.05
289
2028
210
1348
1.75
10.28
3.6
2.5
5.27
6.40
e6/l
0.40
191
1210
438
3397
1.61
10.22
6.3
4.6
0.00
0.00
estimate
-0.00
106
641
393
2971
1.61
10.19
9.8
5.6
1.22
1.21
mmol/l
0.10
355
2714
163
974
1.84
10.15
4.2
2.2
12.36
13.36
umol/l
1.18
150
912
441
3432
1.60
10.10
5.0
3.4
0.00
0.01
estimate
0.80
97
624
487
3908
1.59
9.59
7.4
4.6
6.96
6.65
mmol/l
2.04
454
3636
76
353
2.27
9.47
1.2
1.1
—
147.00
titre
—
0
8
148
894
1.80
8.81
4.3
2.2
2.31
2.35
g/l
0.37
134
836
140
839
1.80
8.55
4.1
2.2
21.70
23.34
%
0.77
119
733
78
385
2.13
8.37
1.4
1.2
—
—
—
0
0
274
1970
1.58
8.37
2.5
2.1
181.84
255.94
u/l
0.50
256
1853
719
6459
1.82
8.19
5.9
4.7
1.89
2.07
mu/l
0.48
672
5941
772
7109
2.16
8.04
22.8
14.4
139.46
139.71
mmol/l
2.09
761
6912
96
520
1.96
8.00
2.5
2.4
5.12
7.39
ug/l
0.98
86
461
92
491
1.98
8.00
5.4
3.4
122.89
76.70
ng/l
1.84
82
440
225
1560
1.61
7.94
2.5
1.7
0.96
1.06
mg/l
0.36
167
1177
268
1938
1.56
7.90
6.5
3.6
7.39
7.40
ph
1.77
54
386
108
613
1.88
7.83
2.0
2.1
0.22
0.22
g/l
0.07
99
582
60
274
2.28
7.79
1.2
1.2
0.24
1.69
u/ml
—
5
17
90
485
1.96
7.61
3.7
2.6
70.19
72.19
e9/l
0.23
73
371
384
3022
1.50
7.55
13.2
9.1
0.00
0.00
e9/l
0.36
320
2488
191
1288
1.63
7.51
4.1
2.7
535.71
543.14
mosm/kgh2o
0.17
177
1107
771
7130
2.08
7.39
23.0
14.5
3.98
3.96
mmol/l
1.91
759
6917
387
3060
1.49
7.38
3.8
2.6
104.22
111.46
ug/l
0.47
359
2823
247
1779
1.55
7.31
3.7
2.9
1282.89
1017.50
ng/l
0.63
213
1501
247
1791
1.54
7.05
4.3
3.0
0.17
0.48
e6/l
4.44
210
1348
347
2712
1.48
6.86
4.5
3.1
5.81
5.78
ph
0.08
24
215
306
2333
1.49
6.85
4.5
3.5
62.69
102.66
e6/l
0.89
230
1639
212
1498
1.56
6.76
1.6
1.5
19.16
21.17
nmol/l
1.45
189
1283
148
964
1.65
6.62
1.4
1.2
—
—
—
0
0
397
3203
1.46
6.58
2.8
2.5
—
—
—
0
0
179
1224
1.59
6.56
2.8
2.9
2.42
2.45
mmol/l
2.57
166
1081
252
1864
1.50
6.47
3.5
3.2
746.36
257.15
mg/l
0.65
177
1184
154
1022
1.62
6.38
4.7
3.3
0.83
0.82
mmol/l
0.93
144
967
791
7440
2.23
6.35
14.9
9.8
25.02
26.11
u/l
1.25
777
7185
216
1553
1.53
6.32
4.8
3.3
—
—
—
0
0
239
1759
1.50
6.25
4.3
2.9
—
—
—
0
0
192
1350
1.55
6.21
1.7
1.7
464.22
24129118.12
pmol/l
1.31
158
1119
260
1953
1.48
6.13
3.8
3.8
15.66
9.36
mg/mmol
0.51
181
1202
187
1312
1.55
6.09
1.8
1.8
—
—
—
0
0
261
1972
1.47
5.94
4.3
3.0
71.63
91.26
e6/l
0.13
216
1514
88
511
1.81
5.93
2.9
2.7
65.57
67.26
g/l
1.25
83
471
817
7820
3.20
5.90
30.3
18.8
39.73
40.19
%
1.37
778
7323
95
566
1.77
5.87
7.5
3.5
1.86
2.04
mmol/l
0.18
83
465
91
537
1.78
5.81
2.2
2.9
10.11
10.68
g/l
0.39
82
497
103
630
1.72
5.81
3.4
2.1
321.94
367.71
nmol/l
1.77
96
588
30
114
2.69
5.79
1.4
1.3
119.20
123.18
u/ml
—
5
22
23
76
3.08
5.68
1.4
1.5
—
—
—
0
0
127
829
1.63
5.60
1.7
1.5
—
—
—
0
0
265
2029
1.45
5.57
3.6
3.1
7.36
7.59
mmol/l
0.35
240
1726
816
7824
2.99
5.50
29.9
18.7
255.96
252.57
e9/l
0.70
801
7627
816
7827
2.97
5.44
29.7
18.7
90.91
90.81
fl
0.24
809
7715
31
124
2.56
5.42
1.2
1.3
—
—
—
0
0
816
7828
2.97
5.42
29.7
18.6
30.22
30.26
pg
0.24
809
7714
816
7829
2.96
5.40
29.9
18.7
4.46
4.50
e12/l
1.61
799
7613
816
7831
2.95
5.35
29.9
18.7
6.68
6.63
e9/l
0.34
800
7612
816
7833
2.93
5.31
30.0
18.8
133.69
135.42
g/l
2.83
810
7717
105
662
1.67
5.30
3.4
2.6
1.87
1.81
%
0.27
92
605
777
7325
1.89
5.20
18.2
11.9
—
—
—
0
0
691
6329
1.54
5.13
6.7
5.4
41.27
39.49
mmol/mol
3.76
655
5896
328
2641
1.40
5.11
2.0
1.9
100.37
96.22
pmol/l
0.85
183
1361
114
744
1.62
5.02
1.3
1.3
—
—
—
0
0
15
32
4.75
5.01
3.1
3.4
—
—
—
0
0
38
174
2.24
4.98
1.4
1.4
9.19
10.32
u/l
0.25
31
143
156
1101
1.51
4.87
1.7
1.6
—
—
—
0
0
71
411
1.80
4.85
2.4
2.1
11.12
12.95
nmol/l
0.90
65
372
159
1130
1.50
4.80
1.7
1.7
1359.15
1194.93
nmol/l
1.11
115
864
17
52
3.32
4.77
1.2
1.1
—
—
—
0
0
31
134
2.36
4.64
1.2
1.2
245.71
232.20
u/ml
0.10
21
81
49
255
1.98
4.64
1.1
1.1
—
—
—
0
0
73
433
1.75
4.60
1.5
1.8
1.08
1.36
g/l
1.10
66
402
90
568
1.66
4.53
1.2
1.2
—
—
—
0
0
26
105
2.52
4.50
1.1
1.8
0.54
0.91
g/l
1.06
21
80
152
1086
1.49
4.46
3.1
2.6
0.76
1.11
e6/l
0.75
106
614
283
2265
1.38
4.43
3.7
3.2
31.46
30.94
u/l
0.07
267
2160
18
61
2.99
4.30
1.1
1.3
—
—
—
0
0
9
13
6.98
4.17
6.3
2.3
—
—
—
0
0
200
1526
1.41
4.12
5.5
3.6
1.02
1.02
kg/l
0.38
22
214
539
4796
1.35
4.09
4.3
3.6
—
—
—
0
0
221
1719
1.39
4.06
8.5
6.4
—
—
—
0
0
26
111
2.39
4.03
1.3
1.3
24.69
24.74
u/l
0.00
21
95
46
247
1.91
4.01
9.1
4.7
—
—
—
0
0
11
23
4.83
3.88
2.6
1.1
—
—
—
0
0
18
65
2.81
3.87
1.1
1.3
—
—
—
0
0
40
208
1.97
3.83
1.5
1.2
—
—
—
0
0
68
418
1.68
3.81
4.9
3.4
4.31
4.53
pmol/l
0.67
63
366
262
2113
1.35
3.80
2.8
2.2
—
—
—
0
0
42
223
1.93
3.80
1.2
1.2
—
—
—
0
0
11
24
4.63
3.75
1.9
1.4
2.76
2.13
umol/l
0.93
11
24
39
203
1.97
3.73
1.5
1.4
249.90
297.55
ug/g
0.73
21
119
105
721
1.52
3.72
11.2
7.9
5.21
5.09
kpa
0.47
99
697
105
721
1.52
3.72
11.2
7.9
11.89
12.36
kpa
0.47
99
699
8
12
6.72
3.68
1.1
1.1
—
—
—
0
0
21
85
2.51
3.65
1.1
1.3
—
74.28
—
0
5
25
112
2.27
3.51
1.1
1.0
—
—
—
0
0
18
69
2.64
3.49
2.2
2.5
—
—
—
0
0
94
640
1.53
3.47
6.2
3.9
—
—
—
0
0
81
535
1.57
3.42
4.7
3.4
1.23
1.23
mmol/l
0.30
73
469
21
88
2.42
3.41
1.8
1.3
—
—
—
0
0
705
6613
1.43
3.41
4.4
3.8
1.28
1.29
mmol/l
0.17
652
6095
203
1599
1.36
3.39
2.8
2.2
—
—
—
0
0
9
18
5.04
3.37
3.3
1.4
—
—
—
0
0
726
6859
1.45
3.25
4.8
4.2
1.48
1.49
mmol/l
0.19
679
6359
232
1884
1.32
3.13
4.7
3.1
—
—
—
0
0
11
30
3.70
3.09
1.7
1.3
31.27
31.50
umol/l
0.02
11
30
518
4674
1.29
3.07
3.7
3.0
45.92
46.35
u/l
0.04
490
4387
19
81
2.38
3.00
1.1
1.2
—
—
—
0
0
727
6891
1.43
2.99
5.0
4.3
4.63
4.73
mmol/l
1.88
682
6423
64
414
1.59
2.98
6.6
5.2
—
—
—
0
0
653
6097
1.33
2.86
21.6
15.3
14.70
14.79
%
0.16
647
5995
49
300
1.67
2.84
2.0
1.8
—
—
—
0
0
736
7008
1.43
2.79
5.4
4.7
2.73
2.81
mmol/l
1.61
690
6488
9
23
3.94
2.78
2.2
2.5
48588.89
35626.30
ug/l
—
9
23
73
496
1.52
2.75
15.9
8.5
—
—
—
0
0
5
6
8.37
2.75
1.2
1.2
—
—
—
0
0
12
40
3.03
2.70
3.7
3.0
—
—
—
0
0
9
24
3.78
2.67
2.8
1.8
32.90
57.02
ug/l
—
9
24
66
447
1.52
2.54
2.2
2.4
—
—
—
0
0
11
37
3.00
2.49
1.2
1.4
149.45
156.42
mmol/24h
0.06
11
37
7
16
4.40
2.48
3.6
1.4
—
—
—
0
0
27
478
0.55
2.47
1.5
1.4
—
—
—
0
0
17
76
2.26
2.45
1.5
1.8
46.58
63.39
%
0.81
12
54
6
12
5.03
2.40
1.2
2.3
—
—
—
0
0
8
22
3.66
2.37
1.7
1.5
—
—
—
0
0
61
414
1.51
2.34
6.1
3.8
7.40
7.41
ph
—
6
58
65
450
1.48
2.28
1.5
1.2
—
—
—
0
0
97
724
1.38
2.27
11.8
7.9
1.57
1.24
mmol/l
0.31
75
581
708
6755
1.32
2.17
5.2
4.3
6.05
5.88
mmol/l
2.03
661
6184
67
474
1.45
2.12
4.3
2.9
144.88
160.32
ng/l
0.22
59
428
15
68
2.23
2.12
3.3
2.9
1.95
1.82
g/24h
—
8
43
23
124
1.88
2.08
1.0
1.0
—
—
—
0
0
48
318
1.54
2.08
2.3
2.3
—
—
—
0
0
5
10
5.02
2.07
5.2
2.3
1.22
1.19
mmol/l
—
5
10
68
485
1.44
2.07
1.7
1.4
—
—
—
0
0
92
693
1.37
2.05
1.7
1.4
—
—
—
0
0
10
38
2.65
2.01
1.2
1.6
—
—
—
0
0
17
84
2.05
1.96
1.2
1.0
0.55
2.88
u/ml
—
6
38
23
128
1.82
1.91
7.0
2.3
—
—
—
0
0
16
79
2.05
1.86
1.7
1.5
—
—
—
0
0
111
875
1.31
1.84
1.3
1.3
—
—
—
0
0
6
17
3.55
1.84
1.0
1.0
—
—
—
0
0
6
17
3.55
1.84
1.0
1.2
—
—
—
0
0
23
130
1.79
1.83
2.7
3.8
4.48
4.25
e9/l
0.13
23
130
19
101
1.90
1.82
1.4
1.7
—
—
—
0
0
9
35
2.59
1.80
3.6
3.1
460.22
870.00
u/ml
—
9
35
21
116
1.83
1.80
1.8
1.3
—
—
—
0
0
5
13
3.86
1.71
60.0
6.3
—
—
—
0
0
34
220
1.57
1.67
6.9
3.9
0.19
0.27
g/l
0.39
16
87
23
136
1.71
1.60
2.7
4.1
59.43
57.29
%
0.34
23
136
221
1922
1.20
1.56
4.2
3.6
—
—
—
0
0
7
27
2.61
1.51
1.1
1.3
—
—
—
0
0
90
710
1.30
1.51
1.6
1.6
—
—
—
0
0
45
318
1.44
1.49
4.0
3.1
—
—
—
0
0
226
2564
0.84
1.49
3.2
2.7
—
—
—
0
0
14
72
1.96
1.49
3.6
4.0
—
—
—
0
0
9
39
2.32
1.43
5.4
3.3
—
—
—
0
0
25
157
1.61
1.42
4.6
3.9
—
—
—
0
0
67
512
1.34
1.42
1.2
1.2
85.60
137.63
iu/ml
0.90
29
212
13
67
1.96
1.39
3.4
3.0
61.23
55.08
%
0.53
13
62
18
104
1.75
1.38
1.4
1.2
4.30
5.57
u/ml
—
10
46
21
127
1.67
1.37
2.8
3.9
—
—
—
0
0
55
727
0.74
1.37
1.2
1.3
—
—
—
0
0
26
167
1.57
1.36
2.8
2.2
88.55
108.21
ug/min
0.15
17
99
42
301
1.42
1.32
6.4
4.1
—
—
—
0
0
91
734
1.27
1.31
1.3
1.4
—
—
—
0
0
9
43
2.10
1.30
1.0
1.0
—
—
—
0
0
37
260
1.44
1.29
6.8
4.5
24.20
25.07
mmol/l
1.26
31
249
10
48
2.10
1.28
1.4
1.8
47.37
38.43
%
—
10
48
81
647
1.28
1.26
3.2
4.3
2.61
30.24
ug/l
1.45
66
531
6
25
2.41
1.24
1.0
1.1
1815.33
1352.36
miu/ml
—
6
25
23
147
1.58
1.24
1.3
1.4
6.06
8.77
e6/l
0.19
17
113
23
147
1.58
1.24
1.3
1.4
926.78
966.47
e6/l
0.01
18
117
9
45
2.01
1.23
1.0
1.0
—
—
—
0
0
12
63
1.92
1.23
4.6
2.3
—
—
—
0
0
21
132
1.61
1.21
2.8
2.7
15.05
16.34
%
1.38
11
68
91
744
1.25
1.18
2.3
2.7
5.68
8.30
umol/l
1.42
82
637
12
64
1.89
1.18
1.0
1.1
—
—
—
0
0
16
94
1.72
1.18
1.1
1.1
0.09
1.79
u/ml
—
5
45
22
142
1.56
1.15
2.0
2.1
4.30
5.00
mmol/24h
0.63
22
126
10
51
1.97
1.11
1.5
1.1
—
—
—
0
0
21
136
1.56
1.09
1.5
1.7
—
—
—
0
0
143
1236
1.19
1.09
4.4
3.7
530.72
326.90
ng/l
0.43
107
920
217
1946
1.16
1.05
1.4
1.5
—
—
—
0
0
66
528
1.27
1.05
1.5
1.4
—
—
—
0
0
16
98
1.65
1.04
3.1
2.9
—
—
—
0
0
17
106
1.62
1.03
9.4
3.0
72.11
59.68
%
1.60
17
106
11
60
1.84
1.03
5.5
3.0
—
—
—
0
0
19
124
1.54
0.97
1.2
1.5
—
—
—
0
0
0
32
0.00
0.95
0.0
1.1
—
202.47
—
0
32
58
464
1.27
0.94
2.4
2.7
4.23
5.32
e9/l
0.74
45
383
119
1028
1.18
0.93
3.5
2.8
3.04
2.64
e6/l
0.14
73
562
21
142
1.49
0.93
3.7
4.1
—
—
—
0
0
6
29
2.08
0.89
1.0
1.1
—
—
—
0
0
13
79
1.66
0.88
1.3
2.0
—
—
—
0
0
10
56
1.80
0.88
1.2
1.1
—
—
—
0
0
27
195
1.40
0.87
1.3
1.3
—
—
—
0
0
16
104
1.55
0.85
1.1
1.2
—
—
—
0
0
13
80
1.63
0.85
1.2
1.3
—
—
—
0
0
6
32
1.88
0.82
2.3
3.3
—
—
—
0
0
8
47
1.71
0.81
2.6
4.7
10.22
10.91
%
—
8
47
94
807
1.19
0.80
1.6
1.6
—
—
—
0
0
17
115
1.49
0.77
1.2
1.1
0.47
3.42
u/ml
—
7
65
20
279
0.71
0.77
3.3
1.5
—
—
—
0
0
25
183
1.38
0.76
3.3
3.7
1.52
2.00
ratio
—
5
18
25
184
1.37
0.74
4.3
3.0
—
—
—
0
0
8
132
0.60
0.74
1.1
1.1
—
—
—
0
0
40
317
1.28
0.73
1.3
1.4
25.21
29.23
iu/l
0.33
35
271
20
142
1.42
0.73
1.8
2.4
127.42
130.81
g/l
0.38
12
113
17
117
1.46
0.72
3.8
2.6
—
—
—
0
0
11
68
1.63
0.72
1.1
1.2
—
—
—
0
0
5
26
1.93
0.70
1.0
1.0
—
—
—
0
0
7
43
1.63
0.67
1.3
1.6
—
—
—
0
0
12
78
1.55
0.65
1.4
1.1
—
—
—
0
0
20
146
1.38
0.64
2.1
1.6
6786.64
15066.81
e6/l
0.88
14
117
8
131
0.61
0.64
1.1
1.1
—
—
—
0
0
21
280
0.74
0.63
3.3
1.5
—
—
—
0
0
41
335
1.24
0.61
17.2
10.2
—
—
—
0
0
12
175
0.68
0.61
9.7
1.9
—
—
—
0
0
21
277
0.75
0.60
3.3
1.5
—
—
—
0
0
21
276
0.75
0.59
3.0
1.5
—
—
—
0
0
616
6002
1.10
0.58
26.8
16.3
332.12
332.52
g/l
0.48
611
5958
12
173
0.69
0.58
1.3
1.1
—
—
—
0
0
14
98
1.44
0.56
1.1
1.1
0.36
0.82
u/ml
—
5
42
8
55
1.46
0.56
1.5
1.2
2208.00
2077.40
e6/l
—
8
35
6
37
1.63
0.55
1.8
2.1
1.95
2.28
ug/l
—
6
32
20
262
0.76
0.55
3.4
1.5
—
—
—
0
0
66
574
1.16
0.53
1.5
1.4
—
—
—
0
0
32
261
1.24
0.50
2.8
2.3
501.82
3833.97
u/l
—
9
113
17
127
1.35
0.50
1.2
1.2
—
—
—
0
0
14
101
1.39
0.49
1.1
1.0
1.79
6.80
u/ml
—
8
55
18
136
1.33
0.49
1.2
1.4
—
—
—
0
0
7
45
1.56
0.49
1.0
1.0
—
—
—
0
0
7
48
1.46
0.47
1.0
1.1
209.29
225.45
mg/l
—
7
42
7
49
1.43
0.46
1.4
1.3
74.00
76.65
umol/l
—
7
49
24
297
0.80
0.45
1.1
1.1
—
—
—
0
0
15
112
1.35
0.45
1.3
1.3
140.73
15.42
u/l
0.48
15
98
68
603
1.14
0.44
4.1
2.4
34.05
36.09
u/l
0.18
58
517
8
56
1.43
0.42
1.4
1.2
—
—
—
0
0
5
32
1.57
0.42
1.2
1.2
—
—
—
0
0
8
59
1.36
0.41
1.4
1.5
—
—
—
0
0
28
232
1.21
0.40
1.1
1.3
147.92
274.62
miu/ml
—
7
107
0
19
0.00
0.39
0.0
3.4
—
—
—
0
0
0
19
0.00
0.39
0.0
6.7
—
—
—
0
0
11
80
1.38
0.38
9.1
5.4
12.87
12.22
mg/l
0.18
11
72
22
179
1.24
0.37
2.9
2.4
—
—
—
0
0
12
90
1.34
0.36
2.6
2.7
—
—
—
0
0
16
200
0.80
0.34
1.2
1.2
—
—
—
0
0
6
44
1.37
0.34
1.2
1.8
4.52
8.85
ug/l
—
6
35
6
46
1.31
0.33
1.2
1.5
141.35
184.71
pmol/l
—
6
46
7
53
1.32
0.31
1.0
1.1
—
1.68
—
0
9
18
218
0.82
0.30
3.6
1.5
—
—
—
0
0
8
110
0.72
0.29
2.0
1.6
—
—
—
0
0
12
151
0.79
0.28
1.2
1.5
—
—
—
0
0
8
64
1.25
0.27
2.1
2.0
—
—
—
0
0
176
1679
1.06
0.27
5.3
4.7
2.14
2.46
ug/l
0.33
162
1512
92
986
0.92
0.27
2.7
2.9
0.66
0.77
ug/l
0.69
61
634
193
1847
1.06
0.27
1.7
1.7
1.40
1.36
mmol/l
0.21
167
1556
9
72
1.25
0.25
1.9
2.6
106.56
105.83
mmol/l
—
9
72
9
72
1.25
0.25
1.9
2.6
3.79
3.96
mmol/l
—
9
72
26
226
1.16
0.25
2.8
2.6
—
—
—
0
0
10
126
0.79
0.24
5.5
1.7
—
—
—
0
0
12
147
0.81
0.23
1.2
1.4
—
—
—
0
0
12
147
0.81
0.23
1.2
1.4
—
—
—
0
0
22
190
1.16
0.23
1.8
1.9
8.90
5.21
iu/l
—
5
70
5
39
1.28
0.23
1.2
1.3
—
—
—
0
0
16
135
1.19
0.21
10.3
3.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
1.76
—
0
11
0
11
0.00
0.21
0.0
2.7
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
1859.50
—
0
10
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
86.86
—
0
7
13
108
1.21
0.20
1.2
1.7
—
—
—
0
0
6
49
1.23
0.20
1.2
1.2
7.08
6.41
mmol/l
—
6
44
10
82
1.22
0.17
1.0
1.3
—
—
—
0
0
5
70
0.71
0.16
1.0
1.2
—
—
—
0
0
8
70
1.14
0.16
2.0
2.6
—
—
—
0
0
37
400
0.92
0.15
1.8
1.7
—
—
—
0
0
9
82
1.10
0.15
1.9
1.3
9.72
41.72
mu/l
—
9
75
10
117
0.85
0.13
1.1
1.2
—
—
—
0
0
5
47
1.06
0.09
1.0
1.2
—
—
—
0
0
6
58
1.03
0.08
1.3
2.8
—
—
—
0
0
7
67
1.05
0.08
1.1
1.2
—
—
—
0
0
22
205
1.08
0.08
9.4
8.6
—
—
—
0
0
7
68
1.03
0.08
1.6
1.2
—
—
—
0
0
48
463
1.04
0.06
3.3
2.6
—
—
—
0
0
12
109
1.10
0.06
1.1
1.0
0.96
1.97
u/ml
—
5
43
58
594
0.97
0.04
5.1
3.7
—
—
—
0
0
15
141
1.06
0.03
2.8
3.6
12.99
24.37
mg/l
—
8
88
28
272
1.03
0.02
1.6
1.6
—
—
—
0
0
15
146
1.03
0.00
1.4
1.2
—
—
—
0
0
10
97
1.03
0.00
1.8
1.6
—
—
—
0
0
14
139
1.01
0.00
2.1
1.3
—
—
—
0
0
11
105
1.05
0.00
1.6
1.5
0.32
0.36
nmol/l
0.15
11
83
10
105
0.95
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
4.1
—
—
—
0
0
7
69
1.01
0.00
1.3
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
38.00
—
0
9
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
34.26
—
0
5
0
5
0.00
-0.00
0.0
14.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.6
0.77
1.02
g/l
—
5
51
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
10
100
1.00
-0.00
1.2
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
16.26
—
0
6
6
61
0.98
-0.00
1.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_NAILNAS and mortality.

Females

Parameter HR [95% CI] p-value
L12_NAILNAS 1.733 [1.42, 2.12] < 0.001
Birth year 0.994 [0.99, 1.0] 0.162

During the follow-up period (1.1.1998 — 31.12.2019), 226 out of 1906 females with L12_NAILNAS died.

Males

Parameter HR [95% CI] p-value
L12_NAILNAS 2.137 [1.7, 2.68] < 0.001
Birth year 0.988 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 258 out of 1445 males with L12_NAILNAS died.

Mortality risk

Mortality risk for people of age

years, who have L12_NAILNAS.

N-year risk Females Males
1 0.197% 0.395%
5 1.018% 2.492%
10 2.49% 6.655%
15 4.702% 11.997%
20 8.331% 19.587%

Relationships between endpoints

Index endpoint: L12_NAILNAS – Other and unspecified nail disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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