Other and unspecified nail disorders

L12_NAILNAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L60.8, L60.9
  • Hospital discharge: ICD-9 7038E|7038G|7038X|7039
  • Hospital discharge: ICD-8 70301|7030[8-9]
  • Cause of death: ICD-10 L60.8, L60.9
  • Cause of death: ICD-9 7038E|7038G|7038X|7039
  • Cause of death: ICD-8 70301|7030[8-9]

2 out of 7 registries used, show all original rules.

734

4. Check minimum number of events

None

734

5. Include endpoints

None

734

6. Filter based on genotype QC (FinnGen only)

734

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4733 2702 2009
Only index persons 4307 2489 1818
Unadjusted period prevalence (%)
Whole population 0.07 0.08 0.06
Only index persons 0.08 0.09 0.07
Median age at first event (years)
Whole population 51.51 52.58 50.15
Only index persons 52.27 53.11 51.12

-FinnGen-

Key figures

All Female Male
Number of individuals 734 475 259
Unadjusted period prevalence (%) 0.15 0.16 0.11
Median age at first event (years) 58.17 57.58 59.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
642
Matched controls
6419
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L60.9
ICD-10 Finland
Nail disorder, unspecified
692.5
323.0
422
18
L60.8
ICD-10 Finland
Other nail disorders
337.9
231.8
222
10
RJ410
NOMESCO Finland
NA
122.4
52.7
56
5
RJ421
NOMESCO Finland
NA
120.0
51.7
55
5
RJ190
NOMESCO Finland
NA
180.3
48.6
50
*
RJ411
NOMESCO Finland
NA
57.5
45.3
53
10
RJ422
NOMESCO Finland
NA
+∞
43.2
41
*
QDH00
NOMESCO Finland
Avulsion of toe nail
+∞
42.1
40
*
L60.0
ICD-10 Finland
Ingrowing nail
9.0
34.3
75
93
B35.1
ICD-10 Finland
Tinea unguium
6.7
34.0
91
154
S22
ICPC
Nail symptom/complaint
5.8
28.1
83
159
L03.0
ICD-10 Finland
Cellulitis of finger and toe
5.0
27.5
94
213
E0000UV
ATC
NA
2.5
25.3
308
1750
QDH01
NOMESCO Finland
Excision of nail bed in toe
129.8
23.7
25
*
D01AE16
ATC
amorolfine; topical
3.6
23.6
119
386
RJ511
NOMESCO Finland
NA
83.0
21.8
24
*
XQ848
NOMESCO Finland
Dermatological photography
9.7
21.1
43
47
TQW80
NOMESCO Finland
Local dermatologic skincare
8.0
21.0
48
64
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.7
20.4
94
281
L60.1
ICD-10 Finland
Onycholysis
21.6
20.1
29
14
L84
ICD-10 Finland
Corns and callosities
6.8
19.6
50
79
D01BA02
ATC
terbinafine; oral; topical
2.4
19.3
202
1024
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.7
19.1
145
617
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.8
18.2
39
47
RJ420
NOMESCO Finland
NA
34.0
18.1
23
7
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.9
17.5
44
68
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
5.3
17.4
54
109
L60.3
ICD-10 Finland
Nail dystrophy
51.5
17.1
20
*
RJ414
NOMESCO Finland
NA
92.5
16.6
18
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
23.8
16.5
23
10
D07AD01
ATC
clobetasol; topical
2.6
15.9
127
552
127
Kela drug reimbursment
Transplant complication
10.8
15.8
30
29
A46
ICD-10 Finland
Erysipelas
2.8
15.6
112
456
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
5.8
15.5
44
80
J01DB01
ATC
cefalexin; oral
2.3
15.2
543
4506
D07AC01
ATC
betamethasone; topical
2.1
15.1
243
1468
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.7
14.5
64
184
Z94.0
ICD-10 Finland
Kidney transplant status
13.8
14.3
24
18
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.7
14.2
103
420
A10AE05
ATC
insulin detemir; parenteral
4.1
14.2
56
146
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.3
13.8
73
242
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
8.2
13.2
29
37
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
6.0
13.2
36
63
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
13.1
127
607
XQ845
NOMESCO Finland
Dermatoscopy
9.6
12.6
25
27
A10AA02
ATC
NA
5.4
12.5
37
72
A10AE04
ATC
insulin glargine; parenteral
3.0
12.3
75
274
J01MA02
ATC
ciprofloxacin; systemic
1.9
12.1
250
1625
L04AA06
ATC
mycophenolic acid; systemic
7.5
12.1
28
39
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.2
12.0
64
214
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.7
11.9
87
357
S18
ICPC
Laceration/cut
1.8
11.7
273
1844
J01FF01
ATC
clindamycin; systemic
2.0
11.6
185
1089
C03CA01
ATC
furosemide; systemic
2.0
11.6
165
931
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
13.9
11.5
19
14
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
6.5
11.5
29
46
RJ425
NOMESCO Finland
NA
+∞
11.5
11
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
20.5
11.2
16
8
L04AD01
ATC
ciclosporin; systemic
7.3
11.1
26
37
SPAT1260
SPAT
Consultation of another employee
2.1
10.9
134
709
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.5
10.6
50
153
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.7
10.5
45
127
L57.0
ICD-10 Finland
Actinic keratosis
2.9
10.5
66
247
J02AC02
ATC
itraconazole; systemic
2.1
10.5
133
714
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
6.6
10.4
26
41
SPAT1310
SPAT
Counselling related to known health issue
1.8
10.4
220
1426
RJ210
NOMESCO Finland
NA
33.1
10.4
13
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
10.2
82
352
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
9.7
150
864
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
9.7
118
620
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.7
9.7
41
115
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.5
9.6
76
325
TQW99
NOMESCO Finland
Other minor procedure on skin
3.6
9.5
42
122
L17
ICPC
Foot/toe symptom/complaint
1.9
9.5
168
1020
A02BC02
ATC
pantoprazole; systemic
1.7
9.5
404
3204
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
9.5
207
1350
RJ412
NOMESCO Finland
NA
101.4
9.4
10
*
RJ521
NOMESCO Finland
NA
101.4
9.4
10
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
9.4
265
1863
H04AA01
ATC
glucagon; nasal, parenteral
5.2
9.3
28
56
H02AB06
ATC
prednisolone; systemic
1.7
9.3
291
2109
Z71.8
ICD-10 Finland
Other specified counselling
1.9
9.3
160
961
SPAT1263
SPAT
Sampling
1.7
9.2
273
1945
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
6.9
9.2
22
33
N02BE01
ATC
paracetamol; systemic, rectal
1.9
9.1
541
4723
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
5.7
9.1
25
45
A11CC03
ATC
alfacalcidol; systemic
5.7
9.1
25
45
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.5
9.1
19
23
Z49.2
ICD-10 Finland
Other dialysis
11.7
9.1
16
14
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
11.7
9.1
16
14
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.6
9.1
30
67
WZC30
NOMESCO Finland
Teaching
2.2
9.0
95
470
A10AA01
ATC
NA
4.9
9.0
28
59
UJF32
NOMESCO Finland
Coloscopy
1.8
8.8
161
984
137
Kela drug reimbursment
Uraemia requiring dialysis
10.9
8.8
16
15
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
8.8
153
920
RD211
NOMESCO Finland
NA
3.3
8.8
44
142
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
14.3
8.7
14
10
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.2
8.7
45
149
NHQ40
NOMESCO Finland
Amputation of toe
7.1
8.6
20
29
E000001
ATC
NA
1.9
8.6
133
768
TK800
NOMESCO Finland
Hemodialysis
5.3
8.5
25
49
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.1
8.5
106
561
SPAT1262
SPAT
Handing over of treatment supplies
2.0
8.5
122
682
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.8
8.5
54
205
ZXC50
NOMESCO Finland
Cryotherapy
4.6
8.5
28
63
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
91.2
8.4
9
*
V03AE01
ATC
polystyrene sulfonate; oral
8.0
8.4
18
23
L40.8
ICD-10 Finland
Other psoriasis
13.0
8.4
14
11
RJ520
NOMESCO Finland
NA
+∞
8.3
8
*
70309
ICD-8 Finland
Diseases of nail, Unspecified
+∞
8.3
8
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
10.9
8.3
15
14
H3603, E103
ICD-10 Finland
NA
9.6
8.3
16
17
D07AB02
ATC
hydrocortisone butyrate; topical
1.8
8.3
179
1155
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
8.2
115
638
SPAT1153
SPAT
Removal of sutures
1.7
8.2
208
1405
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.0
8.1
46
161
N18.0
ICD-10 Finland
End-stage renal disease
10.2
8.1
15
15
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
10.2
8.1
15
15
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
10.2
8.1
15
15
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
8.0
92
470
A12AA04
ATC
calcium carbonate; oral
7.4
8.0
18
25
R50.9
ICD-10 Finland
Fever, unspecified
2.1
8.0
92
471
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.7
8.0
54
212
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
8.0
152
938
D07AB08
ATC
desonide; topical
2.3
7.9
76
357
S09
ICPC
Infected finger/toe
4.4
7.9
27
63
B05DA
ATC
Isotonic solutions
11.0
7.8
14
13
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
7.7
248
1787
Z00.0
ICD-10 Finland
General medical examination
1.9
7.6
126
743
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
18.6
7.6
11
6
L60
ICD-10 Finland
Nail disorders
12.0
7.6
13
11
QDH05
NOMESCO Finland
Correction of deformity of toe nail
25.3
7.6
10
*
D02AE01
ATC
carbamide; topical
2.7
7.6
52
206
K65.0
ICD-10 Finland
Acute peritonitis
9.0
7.6
15
17
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
10.2
7.6
14
14
SPAT1301
SPAT
No procedures
1.7
7.5
201
1371
J01EA01
ATC
trimethoprim; systemic
1.8
7.5
156
992
S29
ICPC
Skin symptom/complaint other
1.9
7.4
107
598
SPAT1255
SPAT
Intravenous administration of medicine
2.8
7.4
47
177
QCH00
NOMESCO Finland
Avulsion of finger nail
81.0
7.4
8
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.1
7.4
27
68
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
7.3
251
1828
B37.2
ICD-10 Finland
Candidiasis of skin and nail
11.0
7.3
13
12
70308
ICD-8 Finland
Diseases of nail, Alii definiti
+∞
7.3
7
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.3
7.2
35
111
V03AE02
ATC
sevelamer; oral
15.9
7.2
11
7
T89
ICPC
Diabetes insulin dependent
3.3
7.2
34
106
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
7.2
110
628
XCK10
NOMESCO Finland
Photography of fundus of eye
2.3
7.1
67
315
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.4
7.1
20
38
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.6
7.1
50
202
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
7.1
182
1229
L28
ICPC
Limited function/disability (L)
2.0
7.0
95
520
M79.6
ICD-10 Finland
Pain in limb
1.6
7.0
224
1604
H02AB04
ATC
methylprednisolone; systemic
2.0
6.9
96
528
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
6.9
85
448
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
14.0
6.9
11
8
N30.0
ICD-10 Finland
Acute cystitis
2.0
6.9
94
515
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
4.5
6.9
23
53
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
6.9
60
272
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.6
6.8
196
1360
SPAT1079
SPAT
Echocardiography
6.8
6.8
16
24
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
6.8
192
1325
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.1
6.8
80
414
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.1
6.8
76
386
-1
NOMESCO Finland
NA
1.6
6.8
207
1460
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.1
6.8
79
405
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.6
6.7
48
196
RD210
NOMESCO Finland
NA
5.6
6.6
18
33
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
6.6
60
276
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.1
6.6
76
391
A10AE06
ATC
insulin degludec; parenteral
3.7
6.6
27
76
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.5
6.6
47
193
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
10.2
6.6
12
12
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
6.5
65
314
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.5
6.5
28
82
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.7
6.5
43
169
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
6.5
69
343
S97
ICPC
Chronic ulcer skin
2.8
6.5
39
145
S94
ICPC
Ingrowing nail
7.5
6.4
14
19
J02AC01
ATC
fluconazole; systemic
1.6
6.4
257
1931
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.2
6.4
64
310
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
6.4
77
404
H3600, E103
ICD-10 Finland
NA
6.6
6.4
15
23
A02BC03
ATC
lansoprazole; oral
1.6
6.3
178
1225
WZA90
NOMESCO Finland
Other doctors statement
1.7
6.3
147
959
D01AE15
ATC
terbinafine; topical
2.5
6.3
48
203
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
11.2
6.3
11
10
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
11.2
6.3
11
10
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
6.3
76
397
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.8
6.3
37
135
K59.1
ICD-10 Finland
Functional diarrhoea
2.9
6.3
36
128
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
18.2
6.3
9
5
QCH01
NOMESCO Finland
Excision of nail bed in finger
+∞
6.3
6
*
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.1
6.2
67
333
H13
ICPC
Plugged feeling ear
1.8
6.2
106
629
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
6.2
249
1868
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.6
6.2
20
45
D05AX52
ATC
calcipotriol, combinations; topical
2.7
6.2
41
161
RS221
NOMESCO Finland
NA
5.4
6.2
17
32
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.8
6.2
37
137
H36.00
ICD-10 Finland
Diabetic background retinopathy
5.8
6.2
16
28
H3601, E103
ICD-10 Finland
NA
7.8
6.1
13
17
Z49.0
ICD-10 Finland
Preparatory care for dialysis
7.8
6.1
13
17
C09CA01
ATC
losartan; oral
1.7
6.1
132
845
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.6
6.1
41
163
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
6.8
6.1
14
21
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
6.0
168
1148
S21
ICPC
Skin texture symptom/complaint
2.0
6.0
76
405

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
236
711
4.42
71.52
1.9
1.4
—
—
—
0
0
151
658
2.63
22.47
2.5
1.5
—
—
—
0
0
429
2978
2.06
19.89
9.0
5.7
0.6
0.6
e9/l
0.14
368
2582
436
3066
2.04
19.24
8.9
5.7
1.8
1.9
e9/l
1.35
381
2710
369
2449
2.02
19.13
6.8
4.4
35.6
35.8
g/l
0.38
349
2297
428
2994
2.03
19.12
9.1
5.7
0.0
0.0
e9/l
0.80
370
2597
438
3099
2.03
18.83
9.3
6.0
0.2
0.2
e9/l
0.07
378
2739
582
4634
2.24
17.43
10.8
7.1
77.5
77.5
u/l
0.02
557
4339
471
3476
1.99
17.28
12.2
8.9
4.0
4.0
e9/l
0.15
418
3039
296
1869
1.98
17.19
3.7
2.4
53.6
57.2
u/l
1.08
280
1723
430
3087
1.95
16.99
7.5
6.0
9.9
11.0
umol/l
2.15
411
2930
357
2468
1.87
15.23
2.9
2.2
75.7
76.1
nmol/l
0.10
329
2214
351
2416
1.87
15.16
2.4
2.0
—
—
—
0
0
384
2722
1.86
15.07
9.4
5.8
0.7
0.7
%
0.10
358
2539
106
469
2.47
14.95
17.7
6.2
10.8
9.2
mmol/l
1.51
101
446
394
2831
1.85
14.66
9.6
6.1
8.6
8.4
%
0.43
370
2656
402
2908
1.85
14.62
9.3
5.9
27.9
28.4
%
0.43
376
2712
392
2817
1.84
14.53
9.3
5.8
2.8
2.8
%
0.01
365
2622
396
2870
1.82
14.13
9.2
5.7
56.8
56.8
%
0.03
369
2686
65
231
2.99
14.01
1.1
1.2
—
—
—
0
0
393
2859
1.81
13.68
12.1
6.3
1.2
1.2
mmol/l
0.20
340
2413
226
1403
1.88
13.09
3.0
2.1
2.9
3.0
mg/l
0.26
208
1201
226
1409
1.87
12.88
1.4
1.2
1.2
2.0
u/ml
0.92
78
377
497
3933
1.82
12.52
6.2
4.1
338.4
1925.5
e6/l
—
7
62
232
1474
1.84
12.37
5.0
4.2
—
—
—
0
0
287
1956
1.77
12.02
9.2
5.9
—
—
—
0
0
96
447
2.32
12.00
5.6
3.2
—
—
—
0
0
103
499
2.24
11.72
5.1
4.4
0.9
1.0
%
0.05
34
150
134
723
2.04
11.55
11.1
4.8
1.1
1.0
mmol/l
2.12
127
675
96
458
2.26
11.32
5.3
4.3
0.7
0.6
%
0.14
27
112
544
4488
1.82
11.20
5.7
4.0
12.1
11.7
mm/h
0.23
514
4138
94
448
2.26
11.11
5.3
4.6
0.0
0.1
%
0.58
26
119
316
2250
1.71
11.09
8.8
8.1
1.2
1.2
inr
0.04
106
676
312
2220
1.71
10.94
3.7
3.3
919.0
57.1
ng/l
0.48
218
1480
144
812
1.96
10.92
2.9
1.9
—
—
—
0
0
176
1061
1.87
10.91
1.4
1.3
32.2
31.0
iu/ml
0.04
46
351
508
4127
1.75
10.81
6.2
4.1
—
—
—
0
0
149
856
1.93
10.68
4.4
2.2
11.9
13.3
umol/l
1.81
139
791
144
826
1.92
10.35
1.5
1.3
527.4
485.5
titre
0.08
27
176
352
2615
1.66
10.29
10.3
5.6
1.2
1.2
mmol/l
0.07
317
2378
95
470
2.17
10.23
5.3
4.5
0.3
0.1
%
0.68
30
134
169
1034
1.82
9.89
1.4
1.3
19.8
13.7
u/ml
0.37
70
406
137
794
1.89
9.49
4.5
2.1
2.3
2.4
g/l
0.82
126
738
235
1599
1.69
9.42
5.7
3.7
0.0
0.0
estimate
0.50
94
551
677
6115
2.38
9.40
21.0
12.7
21.5
22.3
mg/l
0.28
578
4763
384
2967
1.62
9.24
5.1
3.4
0.0
0.0
estimate
0.00
97
557
249
1728
1.67
9.22
2.5
2.1
190.2
235.9
u/l
0.27
231
1631
559
4757
1.73
9.09
5.0
3.9
14.8
14.7
pmol/l
0.27
517
4328
251
1753
1.66
9.04
4.2
2.9
—
—
—
0
0
277
1993
1.63
8.81
4.3
3.2
2.3
2.4
mmol/l
0.38
252
1761
129
750
1.87
8.81
2.2
2.3
153.4
127.0
ug/g
0.20
106
583
128
743
1.88
8.78
4.4
2.2
21.2
23.3
%
1.05
111
650
429
3434
1.60
8.68
8.0
4.5
7.0
6.7
mmol/l
1.61
402
3188
244
1710
1.64
8.58
6.5
3.6
7.4
7.4
ph
1.76
49
340
183
1192
1.71
8.50
3.8
2.5
5.2
6.2
e6/l
0.27
163
1040
217
1496
1.64
8.06
4.7
2.6
342.2
5529.3
umol/l
4.99
191
1313
85
441
2.05
8.06
5.5
3.2
125.5
75.6
ng/l
1.89
77
394
87
456
2.03
8.02
2.6
2.4
5.2
7.5
ug/l
0.89
78
403
97
532
1.95
7.87
2.1
2.1
0.2
0.2
g/l
0.03
90
502
202
1377
1.64
7.81
6.5
4.4
—
—
—
0
0
377
2974
1.55
7.78
6.4
4.6
0.0
0.0
estimate
0.00
95
557
380
3010
1.54
7.65
5.1
3.4
0.0
0.0
estimate
0.80
88
547
64
305
2.20
7.55
1.3
1.1
—
201.8
titre
—
0
9
81
424
2.02
7.49
3.9
2.6
70.0
70.7
e9/l
0.06
64
328
188
1273
1.64
7.42
1.5
1.4
2.1
2.4
g/l
2.06
131
787
230
1644
1.58
7.23
3.6
3.3
814.0
245.7
mg/l
0.71
161
1043
15
30
5.08
7.21
3.1
3.5
—
—
—
0
0
191
1315
1.61
7.00
1.6
1.5
19.6
21.2
nmol/l
0.96
170
1119
238
1729
1.56
6.92
4.0
4.0
16.5
9.5
mg/mmol
0.52
165
1069
628
5661
1.76
6.71
5.9
4.7
1.9
2.1
mu/l
0.44
586
5199
677
6249
2.07
6.69
24.2
14.5
139.4
139.7
mmol/l
2.66
668
6076
67
343
2.05
6.59
1.4
1.2
—
—
—
0
0
193
1350
1.58
6.57
2.6
1.6
1.0
1.1
mg/l
0.20
147
1024
219
1578
1.55
6.54
4.0
3.0
1380.1
1051.6
ng/l
0.75
193
1337
336
2656
1.49
6.45
4.0
2.6
110.0
113.7
ug/l
0.18
312
2445
165
1121
1.61
6.32
4.1
2.6
536.5
550.2
mosm/kgh2o
0.32
153
949
271
2057
1.50
6.31
4.8
3.5
69.4
104.6
e6/l
0.63
201
1447
138
900
1.66
6.22
5.0
3.4
0.8
0.8
mmol/l
0.78
129
847
335
2666
1.47
6.11
13.7
9.1
0.0
0.0
e9/l
0.31
275
2188
676
6271
1.99
6.04
24.4
14.5
4.0
4.0
mmol/l
1.92
666
6079
171
1189
1.57
5.90
1.7
1.7
468.8
20914136.4
pmol/l
1.05
140
985
113
710
1.70
5.85
1.8
1.5
—
—
—
0
0
347
2798
1.46
5.82
4.3
3.8
—
—
—
0
0
11
20
5.57
5.82
2.6
1.1
—
—
—
0
0
239
1792
1.49
5.81
3.7
3.1
7.2
7.6
mmol/l
0.74
216
1513
86
501
1.81
5.78
7.8
3.5
1.9
2.0
mmol/l
0.06
72
401
29
110
2.70
5.63
1.2
1.2
265.1
219.9
u/ml
0.38
19
63
215
1590
1.50
5.55
4.6
3.0
0.2
0.5
e6/l
3.89
181
1179
96
586
1.73
5.51
3.6
2.6
1.9
1.8
%
0.49
84
539
17
47
3.68
5.51
1.2
1.1
—
—
—
0
0
161
1127
1.55
5.35
1.8
1.8
—
—
—
0
0
231
1748
1.47
5.28
4.5
3.0
79.3
91.1
e6/l
0.06
191
1335
693
6536
2.08
5.10
15.3
9.7
25.1
26.1
u/l
1.00
679
6312
152
1063
1.54
5.05
2.9
2.8
2.4
2.4
mmol/l
1.63
140
935
187
1370
1.49
4.99
4.9
3.3
—
—
—
0
0
145
1009
1.54
4.92
1.7
1.7
1386.9
1182.8
nmol/l
1.39
105
771
28
113
2.54
4.84
1.2
1.3
—
—
—
0
0
611
5584
1.56
4.84
6.9
5.5
41.4
39.6
mmol/mol
3.54
579
5211
208
1565
1.46
4.83
4.6
2.9
—
—
—
0
0
137
946
1.55
4.81
1.8
1.6
—
—
—
0
0
99
637
1.64
4.67
11.7
7.7
5.2
5.1
kpa
0.40
94
615
99
637
1.64
4.67
11.7
7.7
11.9
12.4
kpa
0.52
94
616
9
11
8.27
4.57
6.3
2.5
—
—
—
0
0
43
215
2.06
4.56
9.4
4.8
—
—
—
0
0
716
6873
2.70
4.51
30.8
18.8
256.1
251.9
e9/l
0.83
701
6696
16
49
3.32
4.49
1.1
1.2
—
—
—
0
0
716
6875
2.69
4.47
30.6
18.7
90.9
90.8
fl
0.11
709
6776
716
6876
2.68
4.45
30.6
18.7
30.2
30.3
pg
0.30
709
6775
716
6877
2.68
4.43
30.8
18.7
4.4
4.5
e12/l
1.97
699
6682
716
6879
2.67
4.39
30.8
18.8
6.7
6.6
e9/l
0.59
700
6680
681
6427
1.83
4.37
18.8
11.9
—
—
—
0
0
716
6881
2.65
4.35
30.9
18.9
133.4
135.4
g/l
3.36
710
6777
23
90
2.61
4.25
1.1
1.9
0.5
0.9
g/l
1.32
18
72
99
654
1.59
4.20
1.3
1.3
—
—
—
0
0
124
863
1.53
4.18
1.4
1.2
—
—
—
0
0
10
23
4.39
4.10
1.9
1.4
2.9
2.1
umol/l
—
10
23
33
156
2.17
4.06
1.5
1.4
9.7
10.2
u/l
0.08
26
128
19
69
2.80
4.04
1.5
1.6
—
—
—
0
0
85
547
1.63
4.01
3.2
2.1
324.5
371.1
nmol/l
1.50
78
510
76
476
1.67
3.99
2.2
2.8
10.2
10.6
g/l
0.25
69
441
71
438
1.69
3.94
16.2
8.6
—
—
—
0
0
232
1838
1.38
3.91
2.9
2.3
—
—
—
0
0
100
676
1.55
3.84
23.1
20.3
1.4
1.2
inr
0.87
17
100
23
95
2.47
3.84
1.1
1.0
—
—
—
0
0
194
1500
1.40
3.76
8.6
6.6
—
—
—
0
0
475
4220
1.36
3.74
4.4
3.6
—
—
—
0
0
10
25
4.04
3.71
1.7
1.4
31.8
31.8
umol/l
—
10
25
282
2321
1.35
3.69
2.1
1.9
99.4
95.6
pmol/l
0.63
155
1202
17
62
2.78
3.61
3.2
1.6
—
—
—
0
0
17
62
2.78
3.61
3.2
1.6
—
—
—
0
0
17
62
2.78
3.61
3.2
1.6
—
—
—
0
0
17
62
2.78
3.61
3.2
1.6
—
—
—
0
0
23
98
2.39
3.61
1.3
1.3
27.6
23.7
u/l
0.20
18
84
36
186
1.98
3.54
1.2
1.2
—
—
—
0
0
16
57
2.85
3.54
1.1
1.3
—
—
—
0
0
9
17
5.35
3.52
3.3
1.3
—
—
—
0
0
181
1398
1.39
3.51
2.9
2.2
—
—
—
0
0
62
383
1.68
3.45
1.5
1.8
1.1
1.3
g/l
0.67
57
358
76
498
1.59
3.35
1.2
1.2
—
—
—
0
0
12
37
3.28
3.35
3.7
3.2
—
—
—
0
0
84
566
1.55
3.29
6.7
4.0
—
—
—
0
0
16
60
2.70
3.24
2.3
2.6
—
—
—
0
0
41
229
1.84
3.23
1.1
1.1
—
—
—
0
0
59
369
1.65
3.15
2.5
2.1
11.0
13.1
nmol/l
0.95
52
334
33
174
1.94
3.09
1.5
1.4
235.7
299.9
ug/g
1.00
18
103
72
476
1.57
3.07
5.0
3.4
1.2
1.2
mmol/l
0.17
65
416
17
69
2.50
2.97
1.1
1.2
—
—
—
0
0
58
367
1.63
2.97
7.1
4.9
—
—
—
0
0
91
640
1.48
2.93
12.4
7.7
1.6
1.2
mmol/l
0.32
70
511
20
413
0.47
2.92
1.5
1.4
—
—
—
0
0
16
64
2.53
2.89
1.6
1.5
48.7
64.2
%
0.66
11
44
171
1351
1.35
2.83
5.6
3.5
1.0
1.0
kg/l
0.77
19
193
6
10
6.04
2.70
1.2
2.5
—
—
—
0
0
85
603
1.46
2.63
1.7
1.4
—
—
—
0
0
7
15
4.70
2.60
3.6
1.5
—
—
—
0
0
5
7
7.18
2.55
5.2
2.0
1.2
1.2
mmol/l
—
5
7
6
11
5.49
2.54
1.2
1.1
—
—
—
0
0
555
5160
1.31
2.53
22.9
15.6
13.8
13.6
%
1.16
548
5050
10
33
3.06
2.53
1.2
1.6
—
—
—
0
0
33
187
1.80
2.53
1.6
1.2
—
—
—
0
0
200
1652
1.29
2.38
4.7
3.1
—
—
—
0
0
614
5810
1.35
2.34
4.4
3.8
1.3
1.3
mmol/l
0.04
570
5354
634
6030
1.38
2.32
4.8
4.2
1.5
1.5
mmol/l
0.54
594
5578
187
2240
0.78
2.29
3.1
2.7
—
—
—
0
0
62
428
1.49
2.22
1.8
1.4
—
—
—
0
0
61
423
1.48
2.15
4.6
2.9
150.8
159.8
ng/l
0.11
54
382
100
760
1.37
2.13
1.3
1.3
—
—
—
0
0
16
75
2.16
2.09
1.1
1.2
—
—
—
0
0
21
110
1.94
2.07
7.4
2.3
—
—
—
0
0
644
6165
1.36
2.04
5.5
4.7
2.7
2.8
mmol/l
2.08
604
5694
6
15
4.02
2.04
1.0
1.2
—
—
—
0
0
6
15
4.02
2.04
1.0
1.0
—
—
—
0
0
56
386
1.49
2.04
2.3
2.5
—
—
—
0
0
16
76
2.13
2.03
1.9
1.2
—
—
—
0
0
12
50
2.42
2.03
2.7
1.5
—
—
—
0
0
17
83
2.07
2.02
3.9
2.3
294.2
53.5
u/ml
0.38
17
78
634
6061
1.34
1.98
5.0
4.3
4.6
4.7
mmol/l
2.47
595
5637
7
21
3.35
1.97
1.7
1.5
—
—
—
0
0
14
64
2.21
1.95
1.8
1.4
—
—
—
0
0
14
64
2.21
1.95
3.6
4.2
—
—
—
0
0
5
11
4.57
1.94
60.0
8.3
—
—
—
0
0
36
231
1.59
1.82
6.9
4.6
24.2
25.2
mmol/l
1.42
30
220
621
5935
1.30
1.82
5.3
4.4
6.1
5.9
mmol/l
1.67
580
5440
22
123
1.81
1.81
1.5
3.0
24.8
34.6
umol/l
2.66
17
106
9
35
2.59
1.80
5.4
2.7
—
—
—
0
0
20
109
1.86
1.79
1.1
1.1
—
—
—
0
0
19
102
1.89
1.77
2.3
1.8
227.8
210.3
pmol/l
0.19
19
97
79
600
1.35
1.71
1.5
1.6
—
—
—
0
0
12
55
2.20
1.68
1.6
2.1
0.8
1.2
e9/l
—
7
28
40
269
1.52
1.67
6.7
4.2
—
—
—
0
0
7
25
2.82
1.65
1.1
1.2
—
—
—
0
0
20
113
1.79
1.62
2.8
3.9
4.5
4.3
e9/l
0.12
20
113
41
281
1.49
1.58
2.4
2.4
—
—
—
0
0
38
257
1.50
1.56
2.1
1.8
—
—
—
0
0
19
107
1.80
1.56
2.8
3.4
—
—
—
0
0
131
1084
1.25
1.52
4.6
3.7
518.5
360.4
ng/l
0.29
100
806
9
39
2.32
1.43
1.0
1.0
—
—
—
0
0
20
118
1.71
1.42
2.8
4.2
59.3
57.4
%
0.25
20
118
11
53
2.09
1.39
5.6
2.8
—
—
—
0
0
16
89
1.82
1.38
1.5
1.2
4.7
3.8
u/ml
—
9
37
36
248
1.47
1.38
1.2
1.5
—
10.7
—
0
6
9
41
2.21
1.37
1.0
1.0
—
—
—
0
0
53
393
1.38
1.37
1.5
1.2
—
—
—
0
0
29
191
1.54
1.36
7.8
3.9
0.2
0.3
g/l
0.40
15
78
6
24
2.51
1.30
2.3
3.8
—
—
—
0
0
72
566
1.30
1.28
3.3
4.3
2.5
28.9
ug/l
1.18
58
462
191
1673
1.19
1.27
4.2
3.6
—
—
—
0
0
9
45
2.01
1.23
1.3
1.1
—
—
—
0
0
16
93
1.74
1.22
1.4
1.7
—
—
—
0
0
38
273
1.41
1.20
17.4
4.0
23.6
24.3
mmol/l
0.71
31
246
6
26
2.32
1.19
1.0
1.2
—
—
—
0
0
49
642
0.75
1.18
1.2
1.4
—
—
—
0
0
16
94
1.72
1.18
9.8
3.2
72.1
60.0
%
1.40
16
94
80
646
1.27
1.17
2.1
2.6
5.9
7.8
umol/l
0.79
71
555
5
20
2.51
1.15
1.6
2.2
1.0
12.3
nmol/l
—
5
14
25
167
1.51
1.13
1.4
1.3
—
—
—
0
0
18
111
1.64
1.13
2.9
2.6
15.1
16.2
%
—
9
57
18
112
1.62
1.09
1.2
1.4
—
—
—
0
0
19
120
1.60
1.09
1.4
1.8
—
—
—
0
0
59
464
1.30
1.07
1.5
1.4
—
—
—
0
0
13
74
1.77
1.07
3.6
2.7
—
—
—
0
0
26
178
1.48
1.06
11.7
4.2
4.2
3.9
mmol/l
1.31
26
163
16
252
0.63
1.05
3.8
1.5
—
—
—
0
0
11
60
1.85
1.03
1.0
1.1
—
—
—
0
0
11
60
1.85
1.03
2.5
2.3
—
—
—
0
0
16
99
1.63
1.00
1.8
1.3
—
—
—
0
0
16
99
1.63
1.00
1.1
1.1
0.5
4.0
u/ml
—
5
36
11
61
1.82
0.99
1.5
1.1
—
—
—
0
0
107
911
1.20
0.98
3.6
2.8
2.5
2.5
e6/l
0.01
65
492
0
29
0.00
0.98
0.0
1.1
—
206.4
—
0
29
22
149
1.49
0.96
2.6
2.3
93.9
114.6
ug/min
0.14
16
90
14
85
1.66
0.95
1.1
1.1
0.4
0.9
u/ml
—
5
36
9
51
1.77
0.94
1.2
1.1
—
—
—
0
0
19
125
1.53
0.94
1.3
1.4
1177.6
991.0
e6/l
0.05
14
102
19
125
1.53
0.94
1.3
1.3
7.8
9.0
e6/l
0.07
13
100
6
27
2.23
0.93
2.3
3.5
—
—
—
0
0
10
55
1.83
0.92
5.2
2.5
—
—
—
0
0
18
118
1.54
0.91
1.9
2.3
129.2
130.5
g/l
—
10
93
17
253
0.66
0.89
3.8
1.5
—
—
—
0
0
8
42
1.91
0.88
3.9
1.5
5.1
8.1
u/l
—
8
33
23
161
1.44
0.87
4.7
3.0
—
—
—
0
0
17
251
0.67
0.86
3.7
1.5
—
—
—
0
0
14
88
1.60
0.85
1.1
1.1
1.8
7.6
u/ml
—
8
48
8
45
1.79
0.84
1.4
1.4
—
—
—
0
0
75
628
1.22
0.84
1.3
1.4
—
—
—
0
0
17
249
0.68
0.83
3.3
1.5
—
—
—
0
0
8
48
1.67
0.79
1.5
1.2
2208.0
2232.7
e6/l
—
8
31
18
123
1.48
0.78
4.2
4.6
—
—
—
0
0
15
99
1.53
0.76
1.3
1.3
140.7
16.1
u/l
0.48
15
85
11
67
1.65
0.75
9.1
5.5
12.9
12.1
mg/l
0.23
11
60
10
160
0.62
0.74
11.4
1.9
—
—
—
0
0
15
101
1.50
0.70
4.1
2.6
—
—
—
0
0
9
145
0.62
0.70
1.2
1.1
—
—
—
0
0
12
77
1.57
0.69
1.1
1.3
0.7
0.6
nmol/l
0.19
12
72
5
27
1.86
0.68
1.2
1.1
—
—
—
0
0
7
42
1.67
0.68
2.7
5.0
10.3
10.8
%
—
7
42
53
439
1.22
0.68
1.2
1.2
57.8
140.9
iu/ml
1.85
24
179
17
236
0.71
0.65
3.6
1.5
—
—
—
0
0
36
287
1.27
0.65
18.2
10.1
23.8
24.6
mmol/l
0.66
31
270
80
694
1.17
0.64
1.7
1.7
—
—
—
0
0
37
297
1.26
0.63
18.7
9.7
—
—
—
0
0
59
501
1.19
0.61
1.6
1.4
—
—
—
0
0
48
400
1.21
0.60
2.7
2.9
4.4
4.0
e9/l
0.56
36
322
7
115
0.60
0.58
1.1
1.1
—
—
—
0
0
7
116
0.60
0.58
1.1
1.1
—
—
—
0
0
6
35
1.72
0.57
1.2
1.3
4.5
6.5
ug/l
—
6
27
9
61
1.48
0.54
1.1
1.2
—
—
—
0
0
21
271
0.77
0.53
1.1
1.1
—
—
—
0
0
10
66
1.52
0.52
1.2
1.3
—
—
—
0
0
34
279
1.23
0.51
3.9
3.1
—
—
—
0
0
182
1694
1.10
0.50
1.4
1.4
—
—
—
0
0
26
207
1.27
0.50
1.1
1.3
147.9
283.4
miu/ml
—
7
102
12
85
1.42
0.47
1.2
1.2
—
—
—
0
0
8
118
0.67
0.46
6.4
1.8
—
—
—
0
0
540
5278
1.09
0.44
27.7
16.2
332.1
332.5
g/l
0.52
535
5240
18
140
1.29
0.42
3.0
3.6
7.4
7.4
ph
0.42
13
113
18
140
1.29
0.42
4.4
3.9
—
—
—
0
0
15
195
0.76
0.42
4.0
1.5
—
—
—
0
0
11
79
1.40
0.41
2.5
2.7
—
—
—
0
0
0
17
0.00
0.40
0.0
3.2
—
—
—
0
0
0
17
0.00
0.40
0.0
6.4
—
—
—
0
0
5
34
1.47
0.40
2.0
2.1
2.2
2.0
ug/l
—
5
29
14
107
1.31
0.37
1.2
1.2
—
—
—
0
0
5
37
1.35
0.37
1.2
1.2
—
—
—
0
0
23
192
1.20
0.32
3.0
2.6
—
—
—
0
0
15
119
1.27
0.32
10.8
3.6
—
—
—
0
0
7
56
1.25
0.29
1.3
1.6
—
—
—
0
0
16
131
1.23
0.27
1.7
1.6
4338.8
15577.6
e6/l
1.52
11
103
81
865
0.93
0.23
2.9
2.9
0.7
0.8
ug/l
0.41
56
556
15
179
0.83
0.23
1.2
1.2
—
—
—
0
0
5
41
1.22
0.22
1.0
1.5
0.8
1.0
g/l
—
5
41
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
2.6
—
—
—
0
0
5
43
1.16
0.21
1.0
1.1
196.6
225.8
mg/l
—
5
38
0
13
0.00
0.21
0.0
5.0
—
53.7
—
0
13
0
13
0.00
0.21
0.0
1.7
—
94.7
—
0
6
0
14
0.00
0.20
0.0
2.8
—
—
—
0
0
6
52
1.16
0.19
1.5
1.1
—
—
—
0
0
6
53
1.13
0.18
1.3
2.6
—
—
—
0
0
7
58
1.21
0.18
1.3
1.6
13.0
17.5
ug/l
—
7
58
12
100
1.20
0.18
1.3
1.6
—
—
—
0
0
7
59
1.19
0.18
1.6
1.2
—
—
—
0
0
574
5688
1.04
0.16
21.0
13.6
39.4
40.0
%
0.77
408
4208
13
111
1.17
0.16
1.3
1.5
—
—
—
0
0
37
400
0.92
0.15
3.1
2.6
—
—
—
0
0
9
80
1.13
0.15
1.9
1.7
—
—
—
0
0
21
189
1.11
0.14
9.0
8.3
—
—
—
0
0
15
132
1.14
0.13
2.8
2.1
—
—
—
0
0
167
1628
1.03
0.12
1.7
1.6
1.4
1.4
mmol/l
0.18
147
1374
10
87
1.15
0.09
1.0
1.1
—
—
—
0
0
6
57
1.05
0.08
2.5
1.9
—
—
—
0
0
6
58
1.03
0.08
1.2
1.2
—
—
—
0
0
5
61
0.82
0.08
1.6
2.5
—
—
—
0
0
11
123
0.89
0.08
1.5
1.3
—
—
—
0
0
152
1492
1.02
0.07
5.5
4.7
2.3
2.5
ug/l
0.16
140
1341
9
87
1.03
0.07
1.8
1.5
0.4
0.4
nmol/l
—
9
69
9
88
1.02
0.07
1.2
1.4
—
—
—
0
0
23
217
1.06
0.06
3.0
2.1
142.4
4493.8
u/l
—
5
94
25
238
1.05
0.05
1.6
1.6
—
—
—
0
0
52
506
1.03
0.04
4.9
3.8
—
—
—
0
0
12
129
0.93
0.03
1.3
1.5
—
—
—
0
0
12
127
0.94
0.01
3.1
3.5
11.3
24.8
mg/l
—
7
79
12
127
0.94
0.01
2.3
1.3
—
—
—
0
0
12
125
0.96
0.00
1.2
1.4
—
—
—
0
0
12
125
0.96
0.00
1.2
1.4
—
—
—
0
0
35
352
0.99
0.00
1.9
1.7
—
—
—
0
0
10
101
0.99
0.00
1.1
1.1
—
—
—
0
0
6
63
0.95
0.00
1.5
2.5
107.3
105.7
mmol/l
—
6
63
0
8
0.00
0.00
0.0
1.3
—
2.0
—
0
8
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
64
0.94
0.00
1.2
1.2
—
—
—
0
0
7
71
0.99
0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
2064.4
—
0
9
6
63
0.95
0.00
1.5
2.5
3.7
3.9
mmol/l
—
6
63
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
38.0
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
18.0
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
0.00
2.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
4.1
—
—
—
0
0
7
71
0.99
0.00
1.9
1.4
6.0
46.2
mu/l
—
7
66
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
16.3
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
34.3
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
14.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_NAILNAS and mortality.

Females

Parameter HR [95% CI] p-value
L12_NAILNAS 1.733 [1.42, 2.12] < 0.001
Birth year 0.994 [0.99, 1.0] 0.162

During the follow-up period (1.1.1998 — 31.12.2019), 226 out of 1906 females with L12_NAILNAS died.

Males

Parameter HR [95% CI] p-value
L12_NAILNAS 2.137 [1.7, 2.68] < 0.001
Birth year 0.988 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 258 out of 1445 males with L12_NAILNAS died.

Mortality risk

Mortality risk for people of age

years, who have L12_NAILNAS.

N-year risk Females Males
1 0.197% 0.395%
5 1.018% 2.492%
10 2.49% 6.655%
15 4.702% 11.997%
20 8.331% 19.587%

Relationships between endpoints

Index endpoint: L12_NAILNAS – Other and unspecified nail disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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