Cyst of Bartholin Gland

N14_BARTHOCYS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N75.0
  • Hospital discharge: ICD-9 6162A
  • Cause of death: ICD-10 N75.0
  • Cause of death: ICD-9 6162A

2 out of 7 registries used, show all original rules.

1491

4. Check minimum number of events

None

1491

5. Include endpoints

None

1491

6. Filter based on genotype QC (FinnGen only)

1491

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENINF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N75
Name in latin
Cysta glandulae vestibularis majoris (Bartholini)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9428 9428 -
Only index persons 9229 9229 -
Unadjusted period prevalence (%)
Whole population 0.27 0.27 -
Only index persons 0.34 0.34 -
Median age at first event (years)
Whole population - 39.12 -
Only index persons - 38.91 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1491 1491 -
Unadjusted period prevalence (%) 0.51 0.51 -
Median age at first event (years) 39.81 39.81 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1352
Matched controls
13520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N75.0
ICD-10 Finland
Cyst of Bartholin gland
4527.3
323.0
1101
12
LFF00
NOMESCO Finland
Marsupialisation of Bartholin gland
3905.0
323.0
316
*
LFF10
NOMESCO Finland
Excision of Bartholin gland
2067.2
323.0
313
*
6162A
ICD-9 Finland
Inflammatory disease of cervix, vagina and vulva, Cyst of Bartholin's gland
+∞
282.5
261
*
N75.1
ICD-10 Finland
Abscess of Bartholin gland
174.3
248.5
255
18
8473
FHL
Guinea pig or gland excision
415.7
185.5
182
5
N75.8
ICD-10 Finland
Other diseases of Bartholin gland
359.7
129.9
129
*
LFF96
NOMESCO Finland
Other operation on Bartholin gland
+∞
117.4
111
*
P01AB01
ATC
metronidazole; oral, rectal
3.0
81.6
791
4288
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.5
57.2
686
3896
LFA00
NOMESCO Finland
Incision of vulva or perineum
45.1
39.3
48
11
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
6.1
32.4
91
158
N75.9
ICD-10 Finland
Disease of Bartholin gland, unspecified
82.0
28.9
32
*
N90.7
ICD-10 Finland
Vulvar cyst
21.1
26.6
39
19
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
8.9
26.2
56
65
6163A
ICD-9 Finland
Inflammatory disease of cervix, vagina and vulva, Abscess of Bartholin's gland
+∞
26.1
25
*
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
17.9
22.7
35
20
J01DB01
ATC
cefalexin; oral
2.0
21.6
1127
9670
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
21.5
171
715
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.2
20.8
245
1250
LEF10
NOMESCO Finland
Colpoperineoplasty
13.8
20.6
35
26
62212
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Bartholinitis acuta
+∞
18.8
18
*
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
7.8
17.9
41
54
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.3
16.2
153
700
8471
FHL
Incision (and possible drainage)
81.0
14.6
16
*
N76.4
ICD-10 Finland
Abscess of vulva
14.6
14.1
23
16
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
141.4
13.5
14
*
J01DA01
ATC
[U] cefalexin; systemic
1.5
13.2
843
6990
J02AC01
ATC
fluconazole; systemic
1.5
13.1
701
5574
N76.0
ICD-10 Finland
Acute vaginitis
2.4
12.4
104
447
62213
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Bartholinitis chronica
+∞
11.5
11
*
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
8.9
10.8
22
25
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
10.5
334
2319
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
+∞
10.4
10
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
10.4
97
442
LEB20
NOMESCO Finland
Marsupialisation of vaginal cyst
32.8
10.3
13
*
N75
ICD-10 Finland
Diseases of Bartholin gland
26.2
9.8
13
5
R2110
NOMESCO Finland
Giving the first information
2.0
9.6
121
627
X15
ICPC
Vaginal symptom/complaint other
2.5
9.5
71
288
LFW96
NOMESCO Finland
Other operation on vulva or perineum
30.2
9.4
12
*
X16
ICPC
Vulval symptom/complaint
3.6
9.3
41
118
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.7
9.2
181
1099
S10
ICPC
Boil/carbuncle
2.5
9.1
71
295
N06AX11
ATC
mirtazapine; oral
1.5
9.0
407
3046
J01MA02
ATC
ciprofloxacin; systemic
1.5
8.6
410
3096
A02BC02
ATC
pantoprazole; systemic
1.4
8.6
791
6763
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
8.5
280
1949
D28.0
ICD-10 Finland
Benign neoplasm: Vulva
7.4
8.5
19
26
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.5
8.4
303
2152
6146A
ICD-9 Finland
Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Pelvic peritoneal adhesions, female
+∞
8.3
8
*
62200
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Endometritis acuta
+∞
8.3
8
*
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
+∞
8.3
8
*
M54.5
ICD-10 Finland
Low back pain
1.4
8.3
423
3237
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.7
8.2
192
1227
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
8.1
458
3569
WX702
NOMESCO Finland
Supraglottic ventilation device
2.3
8.0
73
331
WX400
NOMESCO Finland
Inhalation anesthesy
2.3
7.9
68
301
N02AX02
ATC
tramadol; systemic, rectal
1.4
7.8
454
3552
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.6
7.4
214
1440
N76.8
ICD-10 Finland
Other specified inflammation of vagina and vulva
5.5
7.2
20
37
8489
FHL
Other measure in this category
30.2
7.2
9
*
N72
ICD-10 Finland
Inflammatory disease of cervix uteri
20.1
7.1
10
5
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.1
305
2244
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
7.0
318
2368
LCA06
NOMESCO Finland
Biopsy of endometrium
1.6
6.9
207
1407
N06AB10
ATC
escitalopram; oral
1.5
6.9
291
2134
G01AA10
ATC
clindamycin; vaginal
1.5
6.8
277
2013
A01AB09
ATC
miconazole; local oral
1.8
6.7
109
622
R10.2
ICD-10 Finland
Pelvic and perineal pain
2.8
6.6
39
140
N06AB06
ATC
sertraline; oral
1.7
6.6
149
941
D11
ICPC
Diarrhoea
1.6
6.3
144
915
61208
ICD-8 Finland
Acute salpingitis and oophoritis, Alia definita
+∞
6.3
6
*
N73.0
ICD-10 Finland
Acute parametritis and pelvic cellulitis
+∞
6.3
6
*
J02AC02
ATC
itraconazole; systemic
1.5
6.2
235
1677
LEB10
NOMESCO Finland
Excision of lesion of vagina
6.3
6.2
15
24
J01CA08
ATC
pivmecillinam; oral
1.3
6.2
664
5687

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
245
1440
1.84
15.51
1.6
1.9
—
—
—
0
0
978
8309
1.51
12.55
4.5
3.9
4925.5
1765.8
e6/l
0.65
13
95
996
8666
1.45
10.00
4.3
4.0
—
—
—
0
0
564
4463
1.42
9.45
1.8
1.8
100.4
99.4
pmol/l
0.16
289
2227
670
5544
1.38
8.32
2.1
2.0
—
—
—
0
0
1363
12827
1.73
8.09
11.8
11.0
18.8
19.2
mg/l
0.19
1091
9778
1035
9230
1.40
7.89
6.8
6.8
73.9
74.6
u/l
0.34
961
8705
505
4021
1.39
7.80
3.0
3.2
71.6
83.3
e6/l
0.22
327
2591
1196
10977
1.45
7.46
4.6
4.4
14.3
14.5
pmol/l
1.99
1120
10243
480
3816
1.38
7.41
1.8
2.1
—
—
—
0
0
702
5941
1.34
7.18
3.5
3.8
—
—
—
0
0
10
13
7.74
7.12
1.8
1.9
—
—
—
0
0
758
6511
1.33
6.90
5.9
5.8
0.2
0.2
e9/l
0.26
681
5814
730
6251
1.33
6.73
5.6
5.5
0.5
0.5
e9/l
0.20
648
5488
750
6454
1.33
6.65
5.7
5.5
2.0
2.0
e9/l
0.78
678
5774
731
6270
1.33
6.62
5.6
5.6
0.0
0.0
e9/l
0.03
652
5496
707
6039
1.32
6.58
5.7
5.6
30.7
29.5
%
2.45
667
5662
247
1779
1.47
6.57
2.0
2.3
116.1
99.9
ug/g
0.32
189
1407
1316
12402
1.52
6.29
5.4
5.1
1.7
2.0
mu/l
1.13
1237
11662
829
7270
1.32
6.27
7.7
8.5
3.8
3.9
e9/l
0.54
738
6427
657
5589
1.31
6.15
5.8
5.6
0.7
0.7
%
1.35
618
5225
678
5794
1.31
6.14
5.7
5.6
2.8
2.8
%
0.12
633
5411
682
5836
1.31
6.10
6.0
5.8
8.1
8.1
%
0.15
647
5494
189
1310
1.51
6.07
1.8
1.6
—
—
—
0
0
481
3934
1.33
5.90
5.6
5.6
—
—
—
0
0
694
5973
1.30
5.87
5.5
5.4
55.3
56.4
%
1.94
657
5614
370
2919
1.36
5.76
2.4
2.7
0.4
0.4
e6/l
0.08
266
2118
225
1646
1.43
5.48
1.2
1.2
—
—
—
0
0
436
3556
1.32
5.36
2.3
2.3
55.0
56.0
u/l
0.30
402
3283
458
3769
1.31
5.27
2.9
2.9
67.5
40.1
ng/l
0.39
248
1999
351
2782
1.34
5.25
1.5
1.4
2.2
2.2
g/l
0.17
216
1727
397
3205
1.33
5.23
2.6
2.8
29.4
70.7
e6/l
1.41
289
2353
1029
9412
1.30
5.13
4.3
3.9
10.3
11.0
mm/h
1.03
971
8787
682
5926
1.28
5.11
5.1
5.6
9.8
9.9
umol/l
0.07
648
5612
1338
12748
1.48
5.05
11.7
11.6
139.7
139.7
mmol/l
0.03
1313
12407
636
5514
1.27
4.74
4.9
5.7
1.2
1.2
mmol/l
2.04
556
4639
361
2913
1.32
4.71
2.4
2.6
—
—
—
0
0
258
1986
1.36
4.63
1.4
1.4
561.8
614.1
titre
0.18
44
421
553
4735
1.27
4.52
3.5
4.2
36.5
36.3
g/l
0.24
506
4420
1337
12791
1.44
4.38
11.8
11.7
3.9
3.9
mmol/l
0.38
1308
12420
214
1617
1.38
4.30
2.2
2.4
4.5
4.9
e6/l
0.13
110
793
451
3788
1.27
4.27
4.9
6.9
1.1
1.1
inr
0.46
144
1206
26
108
2.43
4.23
1.2
1.1
—
—
—
0
0
572
4957
1.25
4.12
4.4
4.9
1.2
1.2
mmol/l
1.24
527
4504
347
2834
1.29
4.08
1.8
2.0
—
—
—
0
0
1469
14405
2.34
4.04
17.9
16.7
267.2
267.0
e9/l
0.04
1440
14093
1469
14412
2.31
3.91
17.9
16.6
90.7
90.6
fl
0.71
1458
14254
1399
13547
1.53
3.84
10.8
10.3
—
—
—
0
0
1469
14416
2.29
3.84
17.8
16.6
30.2
30.1
pg
1.79
1458
14256
1469
14417
2.28
3.82
17.9
16.6
4.4
4.4
e12/l
0.23
1440
14074
404
3388
1.26
3.82
3.2
3.4
7.4
7.4
ph
0.52
58
632
1469
14419
2.27
3.78
17.9
16.7
6.6
6.6
e9/l
0.28
1438
14071
1469
14423
2.25
3.71
18.0
16.7
133.2
132.8
g/l
0.77
1458
14268
219
1701
1.34
3.69
1.3
1.2
—
—
—
0
0
727
6523
1.22
3.64
3.3
4.0
6.3
6.4
mmol/l
1.05
688
5984
349
2896
1.27
3.58
3.6
3.3
—
—
—
0
0
374
3136
1.26
3.50
1.9
2.0
129.3
155.7
u/l
0.43
353
2971
341
2843
1.26
3.34
3.2
3.3
96.9
97.2
%
0.07
332
2753
392
3333
1.24
3.21
1.3
1.3
0.8
1.6
u/ml
2.44
100
925
468
4060
1.22
3.16
2.8
3.2
2.4
2.4
mmol/l
0.06
419
3634
110
784
1.44
3.14
1.2
1.2
—
—
—
0
0
205
1616
1.31
3.12
1.6
1.5
—
—
—
0
0
1172
11124
1.25
3.12
13.6
13.5
13.4
13.6
%
2.22
1160
10894
224
1788
1.30
3.11
1.6
1.7
1141.6
1210.2
nmol/l
0.52
173
1379
129
948
1.39
3.10
1.2
1.2
—
—
—
0
0
692
6250
1.20
3.05
3.6
3.3
0.0
0.0
estimate
0.00
121
1142
1398
13599
1.45
3.04
9.6
9.1
23.8
23.7
u/l
0.07
1362
13183
247
2006
1.28
3.00
2.2
2.5
510.6
518.9
mosm/kgh2o
0.23
215
1695
88
610
1.47
2.92
1.2
1.3
0.2
1.0
u/ml
—
6
60
1270
12203
1.27
2.82
4.1
3.9
5.6
5.7
mmol/l
2.05
1187
11357
145
1105
1.35
2.80
1.4
1.3
29.4
28.2
iu/l
0.16
129
955
52
326
1.62
2.72
2.9
2.9
—
—
—
0
0
118
875
1.38
2.71
2.3
2.0
6532.8
6441.0
u/l
0.01
40
375
1306
12606
1.29
2.69
3.9
3.9
4.8
4.9
mmol/l
0.77
1234
11908
312
2635
1.23
2.69
1.4
1.3
27.5
29.9
iu/ml
0.16
112
841
263
2184
1.25
2.64
2.2
2.3
10.2
8.6
e6/l
0.51
227
1903
31
169
1.85
2.64
1.0
1.1
—
—
—
0
0
49
306
1.62
2.61
1.9
1.8
—
—
—
0
0
689
6279
1.18
2.60
4.8
4.5
0.0
0.0
estimate
0.50
119
1157
695
6340
1.18
2.59
3.6
3.4
0.0
0.0
estimate
1.06
116
1147
1320
12771
1.29
2.58
4.3
4.3
2.9
2.9
mmol/l
0.22
1235
11993
230
1888
1.26
2.56
2.6
3.2
466.6
291.1
ng/l
0.17
132
1185
133
1019
1.34
2.50
1.9
3.1
23.4
46.8
u/ml
2.66
126
987
430
3778
1.19
2.46
2.8
2.6
—
—
—
0
0
107
797
1.37
2.42
1.3
1.4
—
—
—
0
0
127
973
1.33
2.40
1.3
1.3
141.6
195.1
u/ml
0.51
119
898
85
611
1.41
2.37
1.1
1.1
—
—
—
0
0
244
2035
1.24
2.36
2.3
2.6
2.4
2.4
mmol/l
0.53
212
1782
1297
12546
1.26
2.36
3.9
3.9
1.6
1.6
mmol/l
1.22
1220
11796
148
1163
1.30
2.34
1.1
1.1
—
—
—
0
0
136
1059
1.31
2.30
1.4
1.4
—
—
—
0
0
282
2395
1.22
2.30
1.4
1.5
21.8
21.7
nmol/l
0.07
238
2098
279
2368
1.22
2.29
3.4
3.8
—
—
—
0
0
1247
12030
1.22
2.20
3.5
3.5
1.2
1.2
mmol/l
0.03
1164
11267
36
218
1.67
2.20
1.1
1.3
—
—
—
0
0
197
1626
1.24
2.11
2.3
3.1
0.8
0.8
mmol/l
0.24
177
1525
115
888
1.32
2.09
3.1
2.4
4.0
4.0
e9/l
0.03
99
750
5
10
5.01
2.07
1.0
1.1
—
—
—
0
0
692
6389
1.16
2.06
2.9
2.8
76.7
75.2
ug/l
0.14
659
6007
1252
12103
1.21
2.05
12.3
12.1
39.7
39.3
%
1.39
986
9472
152
1227
1.27
1.98
1.8
2.1
388.9
374.0
nmol/l
0.40
137
1130
369
3255
1.18
1.98
5.2
6.3
—
—
—
0
0
113
879
1.31
1.96
2.2
2.8
10.2
10.4
g/l
0.30
103
803
91
686
1.35
1.95
1.8
1.8
1.3
1.4
g/l
0.40
82
630
159
1295
1.25
1.92
2.2
2.4
7.2
5.7
umol/l
0.49
140
1095
34
212
1.62
1.89
1.3
1.2
—
—
—
0
0
19
100
1.91
1.86
2.0
2.7
1.2
1.2
e9/l
0.01
13
67
15
73
2.07
1.81
1.5
1.6
—
7.2
—
0
6
114
899
1.29
1.80
1.2
1.3
60.7
32.8
au/ml
—
5
41
22
123
1.80
1.80
1.2
1.1
—
—
—
0
0
613
5650
1.14
1.80
7.7
8.0
0.0
0.0
e9/l
0.04
507
4638
1161
11187
1.17
1.77
4.6
4.7
37.4
38.3
mmol/mol
4.14
1091
10486
348
3081
1.17
1.77
4.3
4.0
—
—
—
0
0
73
541
1.37
1.77
1.7
1.8
—
—
—
0
0
45
306
1.49
1.74
1.3
1.3
288.5
319.7
ug/g
0.39
27
166
67
492
1.38
1.72
1.3
1.3
—
—
—
0
0
87
669
1.32
1.67
2.0
2.1
4.4
5.6
ug/l
0.51
76
594
226
1940
1.19
1.66
1.7
1.6
—
—
—
0
0
73
549
1.35
1.63
1.7
1.8
—
—
—
0
0
134
1094
1.25
1.62
1.9
2.1
51.7
35.3
u/l
0.53
111
925
333
2964
1.16
1.58
3.2
3.2
—
—
—
0
0
73
553
1.34
1.57
1.7
1.8
—
—
—
0
0
59
432
1.38
1.57
2.1
1.8
—
—
—
0
0
345
3081
1.16
1.56
2.1
1.9
—
—
—
0
0
130
1064
1.24
1.55
19.4
18.9
1.3
1.2
inr
0.55
16
162
72
548
1.33
1.51
1.7
1.8
—
—
—
0
0
71
541
1.33
1.48
2.7
5.5
—
—
—
0
0
45
318
1.43
1.47
2.0
2.0
—
—
—
0
0
105
846
1.26
1.44
2.2
2.5
—
—
—
0
0
38
261
1.47
1.44
1.9
2.3
3.9
4.9
umol/l
0.59
26
187
13
66
1.98
1.43
1.6
2.7
—
—
—
0
0
120
984
1.24
1.42
2.4
2.4
20.6
24.1
au/ml
—
5
67
165
1400
1.20
1.40
1.4
1.4
—
—
—
0
0
288
2562
1.15
1.38
1.3
1.3
8.4
10.7
u/ml
0.23
105
1050
66
507
1.32
1.33
1.7
1.8
—
—
—
0
0
15
83
1.82
1.31
1.2
1.2
—
—
—
0
0
18
106
1.71
1.29
3.7
3.0
—
—
—
0
0
359
3258
1.13
1.29
1.6
1.6
1.3
1.3
mmol/l
0.59
320
2803
293
2625
1.14
1.27
1.7
1.6
—
—
—
0
0
52
388
1.35
1.27
2.3
2.6
—
—
—
0
0
188
1629
1.18
1.27
2.1
2.2
15.0
13.8
umol/l
1.50
179
1510
14
77
1.83
1.25
2.4
3.6
13.2
45.2
mg/l
—
7
50
11
203
0.54
1.24
1.6
2.7
34.9
105.6
ug/min
—
5
137
74
584
1.28
1.23
3.2
2.9
—
—
—
0
0
15
85
1.77
1.23
2.0
2.2
14.4
12.0
%
—
8
39
15
86
1.75
1.19
2.0
2.2
76.5
75.3
%
0.21
15
80
23
149
1.55
1.17
1.1
1.7
—
20.7
—
0
9
22
141
1.57
1.17
1.1
1.3
—
—
—
0
0
74
589
1.27
1.17
2.5
2.3
—
—
—
0
0
10
50
2.01
1.16
1.0
1.1
126.4
170.3
iu/ml
—
10
50
311
2816
1.13
1.16
2.0
2.2
1851.4
3864.8
umol/l
0.85
270
2459
13
72
1.81
1.15
2.7
2.8
588.2
878.8
e6/l
—
5
25
11
58
1.90
1.12
1.9
3.1
0.6
0.2
e9/l
0.38
11
58
68
539
1.27
1.12
4.1
7.2
24.3
24.8
mmol/l
0.56
63
499
325
2958
1.13
1.11
1.7
1.8
0.8
0.9
mg/l
0.42
258
2221
62
486
1.29
1.11
1.2
1.2
—
—
—
0
0
121
1023
1.20
1.11
4.1
3.7
—
—
—
0
0
873
8372
1.10
1.10
3.1
3.1
—
—
—
0
0
54
416
1.31
1.10
1.2
1.2
—
—
—
0
0
5
21
2.39
1.09
1.0
2.5
11.5
18.7
umol/l
—
5
21
7
32
2.19
1.08
1.0
1.1
—
—
—
0
0
13
74
1.76
1.07
1.6
2.7
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
5
22
2.28
1.03
1.4
1.1
—
—
—
0
0
23
156
1.48
0.98
2.3
2.6
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
7
36
1.95
0.97
1.3
1.3
—
—
—
0
0
17
108
1.58
0.96
1.0
1.0
0.2
4.8
u/ml
—
7
35
0
32
0.00
0.95
0.0
1.2
—
—
—
0
0
7
37
1.90
0.94
1.1
1.4
—
—
—
0
0
67
548
1.23
0.89
1.5
1.7
—
—
—
0
0
257
2341
1.12
0.88
1.6
1.6
425.7
44739919.1
pmol/l
2.90
217
1996
116
1003
1.17
0.86
4.3
7.1
0.7
1.1
mmol/l
1.26
86
784
101
864
1.18
0.85
4.3
7.6
96.4
96.3
%
0.08
96
831
39
300
1.31
0.85
2.0
7.3
1.2
1.2
mmol/l
0.07
34
258
8
45
1.78
0.84
2.1
2.1
28.3
29.0
%
—
8
40
8
45
1.78
0.84
1.1
1.5
—
—
—
0
0
10
57
1.76
0.83
1.0
1.2
—
—
—
0
0
111
960
1.17
0.83
2.7
2.6
1.7
1.8
%
1.28
94
849
12
190
0.63
0.83
1.2
1.6
—
—
—
0
0
15
225
0.66
0.82
1.1
1.1
—
—
—
0
0
8
47
1.71
0.80
2.1
2.1
10.1
8.4
%
—
8
42
163
1454
1.14
0.80
2.0
2.2
2.5
2.4
g/l
0.98
152
1355
99
851
1.17
0.80
3.2
3.3
81.1
74.5
ng/l
0.28
92
744
29
216
1.35
0.79
1.4
2.2
—
—
—
0
0
14
90
1.56
0.78
1.0
1.1
—
—
—
0
0
111
967
1.16
0.77
2.0
2.1
0.2
0.2
g/l
0.15
104
915
115
1005
1.16
0.76
4.4
7.0
12.6
13.4
kpa
0.75
106
958
115
1005
1.16
0.76
4.3
7.1
5.1
5.1
kpa
0.03
108
958
35
270
1.30
0.76
1.3
1.2
—
—
—
0
0
19
132
1.45
0.76
1.3
1.7
55.9
62.9
%
0.61
19
132
10
59
1.70
0.76
2.0
1.4
—
—
—
0
0
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
412
3878
1.09
0.74
1.5
1.6
—
—
—
0
0
42
335
1.26
0.72
1.3
1.4
0.5
0.4
nmol/l
0.46
34
266
10
60
1.67
0.72
1.7
1.3
—
—
—
0
0
26
194
1.35
0.71
1.1
1.2
—
—
—
0
0
38
477
0.79
0.71
1.6
2.0
20.0
20.5
s
0.61
32
407
9
57
1.58
0.71
2.0
2.8
674.0
1216.4
u/ml
—
9
57
5
26
1.93
0.70
3.2
1.2
31.7
43.6
%
—
5
19
186
1689
1.12
0.70
1.9
1.9
—
—
—
0
0
15
101
1.49
0.70
1.7
2.0
—
—
—
0
0
26
195
1.34
0.69
1.6
2.1
128.9
129.8
g/l
0.04
17
145
137
1223
1.13
0.69
2.3
4.7
1.0
1.0
mmol/l
0.22
125
1129
10
157
0.63
0.69
2.1
2.3
—
—
—
0
0
263
2836
0.91
0.69
3.0
3.2
335.8
479.8
mg/l
0.19
144
1652
7
117
0.60
0.68
1.0
1.3
—
—
—
0
0
7
117
0.60
0.68
1.0
1.3
—
—
—
0
0
7
117
0.60
0.68
1.0
1.3
—
—
—
0
0
7
117
0.60
0.68
1.0
1.3
—
—
—
0
0
17
238
0.71
0.67
1.2
1.2
2.5
5.6
u/ml
—
8
93
7
43
1.63
0.67
1.9
2.3
3.7
7.7
%
—
7
43
7
43
1.63
0.67
1.9
2.3
—
—
—
0
0
20
145
1.38
0.66
1.4
1.5
—
—
—
0
0
89
774
1.16
0.65
2.2
3.1
2.4
2.1
mmol/l
0.51
77
633
12
78
1.54
0.65
1.0
1.2
—
—
—
0
0
73
625
1.18
0.65
2.2
2.2
—
—
—
0
0
10
62
1.62
0.65
1.1
1.5
126.1
123.8
nmol/l
—
10
62
68
579
1.18
0.65
1.1
1.1
—
—
—
0
0
116
1033
1.13
0.62
3.3
3.9
9.3
12.2
ug/l
0.24
91
792
119
1062
1.13
0.62
1.5
1.4
—
—
—
0
0
30
236
1.28
0.60
1.1
1.1
—
—
—
0
0
30
237
1.27
0.58
1.1
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
2.4
—
—
—
0
0
0
23
0.00
0.58
0.0
3.6
—
—
—
0
0
369
3493
1.07
0.58
3.0
3.0
—
—
—
0
0
279
2975
0.92
0.57
3.3
3.8
9.1
7.2
mg/mmol
0.17
150
1760
16
115
1.40
0.56
1.3
1.3
27.6
32.2
nmol/l
0.43
16
96
148
1347
1.11
0.56
1.3
1.3
—
—
—
0
0
15
107
1.41
0.55
1.0
1.0
0.4
1.2
u/ml
—
5
25
311
2932
1.08
0.55
2.3
2.1
2.5
2.9
mg/l
2.18
269
2516
76
665
1.15
0.54
2.0
1.6
449.2
318.4
mu/l
0.59
66
588
31
249
1.25
0.54
2.3
2.3
—
—
—
0
0
11
75
1.47
0.50
1.0
1.1
—
—
—
0
0
9
65
1.39
0.50
1.0
1.2
1160.3
1606.9
miu/ml
—
9
65
284
2680
1.07
0.49
4.5
3.7
1.0
1.0
kg/l
0.45
32
388
70
615
1.15
0.49
1.2
1.3
215.0
240.4
miu/ml
0.28
38
315
84
749
1.13
0.47
2.3
2.5
65.4
67.4
g/l
1.22
75
695
101
911
1.12
0.47
3.1
3.7
1.5
0.7
%
0.29
16
163
16
210
0.76
0.46
1.6
1.6
—
—
—
0
0
30
246
1.22
0.45
4.8
3.8
51.4
58.1
%
1.53
30
246
117
1068
1.10
0.45
3.2
3.4
4.5
4.5
pmol/l
0.25
104
963
32
265
1.21
0.44
1.2
1.5
—
—
—
0
0
11
78
1.41
0.43
1.1
1.3
—
—
—
0
0
11
78
1.41
0.43
1.1
1.1
—
—
—
0
0
6
91
0.66
0.42
1.2
1.4
6.4
6.8
mmol/l
—
6
64
43
369
1.17
0.42
1.3
1.2
17.2
13.7
u/l
0.55
33
307
20
158
1.27
0.42
1.7
1.3
59.7
64.0
mmol/l
0.23
15
131
0
15
0.00
0.41
0.0
1.8
—
3.6
—
0
5
0
16
0.00
0.41
0.0
5.1
—
0.3
—
0
16
42
361
1.17
0.41
1.3
2.1
1.1
1.5
g/l
2.62
33
316
0
17
0.00
0.40
0.0
6.5
—
—
—
0
0
79
711
1.12
0.40
4.5
7.1
—
—
—
0
0
183
1715
1.08
0.40
1.6
1.4
—
—
—
0
0
74
664
1.12
0.40
1.7
3.1
95.4
154.7
ng/l
2.00
66
595
13
97
1.34
0.39
2.6
2.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
39.8
—
0
8
13
170
0.76
0.38
1.0
1.0
—
—
—
0
0
5
36
1.39
0.38
1.2
1.1
—
—
—
0
0
12
89
1.35
0.38
1.3
1.1
—
—
—
0
0
9
68
1.33
0.37
1.8
1.4
—
—
—
0
0
27
225
1.20
0.37
1.5
1.6
—
—
—
0
0
10
72
1.39
0.37
1.1
1.0
—
—
—
0
0
46
403
1.15
0.36
1.3
1.3
5.5
2.5
u/ml
—
8
48
5
78
0.64
0.35
1.4
1.3
—
65.3
—
0
8
6
42
1.43
0.35
1.2
1.1
—
—
—
0
0
35
301
1.17
0.35
1.4
1.3
6.8
3.3
ug/l
0.37
30
271
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
25
209
1.20
0.34
1.1
1.3
116.2
118.6
u/ml
—
6
38
140
1310
1.08
0.34
1.2
1.2
135.5
157.6
iu/ml
0.24
47
528
58
520
1.12
0.33
1.5
1.4
—
—
—
0
0
141
1321
1.07
0.33
2.2
2.3
24.9
22.7
%
1.02
125
1125
24
285
0.84
0.33
1.2
1.1
—
—
—
0
0
19
231
0.82
0.32
2.1
1.7
3703.2
10889.7
e6/l
1.19
12
159
25
211
1.19
0.31
1.1
1.0
—
—
—
0
0
28
239
1.17
0.31
4.3
3.6
3.4
4.0
e9/l
1.69
28
239
24
202
1.19
0.31
1.1
1.1
—
—
—
0
0
76
696
1.10
0.31
2.5
2.8
73.2
74.4
e9/l
0.10
51
512
26
221
1.18
0.30
1.1
1.3
—
—
—
0
0
7
100
0.70
0.30
1.1
1.2
—
—
—
0
0
58
524
1.11
0.30
1.5
1.4
—
—
—
0
0
39
345
1.13
0.28
1.1
1.2
—
—
—
0
0
20
167
1.20
0.28
1.8
5.6
336.9
378.2
umol/l
0.46
11
145
40
355
1.13
0.28
2.2
3.4
—
—
—
0
0
10
129
0.77
0.28
1.3
2.3
—
—
—
0
0
11
85
1.30
0.28
1.1
1.2
—
—
—
0
0
97
905
1.08
0.27
3.8
3.9
0.3
1.0
%
0.45
19
173
8
66
1.21
0.26
4.9
3.3
—
—
—
0
0
507
4949
1.04
0.26
2.3
2.5
—
—
—
0
0
67
616
1.09
0.26
2.0
1.8
—
—
—
0
0
52
472
1.11
0.26
5.5
9.8
—
—
—
0
0
11
86
1.28
0.26
2.5
3.2
—
—
—
0
0
103
967
1.07
0.25
1.4
1.4
—
—
—
0
0
39
350
1.12
0.24
2.5
3.0
0.1
0.3
g/l
1.68
11
123
15
124
1.21
0.24
4.9
2.8
2.5
48.0
nmol/l
0.51
15
119
6
85
0.70
0.24
1.2
1.4
52.7
24.9
umol/l
—
6
80
114
1077
1.06
0.23
3.4
3.5
—
—
—
0
0
5
39
1.28
0.23
1.0
1.2
152.5
101.7
nmol/l
—
5
27
19
162
1.18
0.23
1.5
1.5
—
—
—
0
0
5
40
1.25
0.22
1.0
1.6
—
—
—
0
0
100
943
1.06
0.22
3.7
3.9
0.0
0.1
%
5.20
21
206
16
135
1.19
0.21
1.1
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.0
—
0
6
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.16
0.21
3.4
1.5
—
—
—
0
0
32
287
1.12
0.21
1.9
1.9
37.4
38.2
g/l
0.26
26
264
0
13
0.00
0.21
0.0
1.1
—
2.6
—
0
5
14
117
1.20
0.20
1.1
1.4
0.9
1.0
g/l
0.27
14
117
19
164
1.16
0.20
1.6
1.2
—
—
—
0
0
19
164
1.16
0.20
6.0
3.5
27.8
46.5
u/ml
0.70
19
164
0
14
0.00
0.20
0.0
7.3
—
—
—
0
0
6
49
1.23
0.20
2.7
1.8
—
—
—
0
0
9
114
0.79
0.20
1.1
1.1
192.8
217.8
mg/l
—
9
95
41
448
0.91
0.20
2.0
2.1
3.1
4.6
iu/l
1.33
16
187
6
50
1.20
0.19
1.2
1.4
—
—
—
0
0
35
317
1.11
0.19
4.7
3.7
20.2
26.2
u/ml
0.71
35
310
58
540
1.08
0.19
1.5
1.5
—
—
—
0
0
28
252
1.11
0.18
4.9
3.6
—
—
—
0
0
11
91
1.21
0.17
1.2
1.4
—
—
—
0
0
19
167
1.14
0.17
1.2
1.2
—
—
—
0
0
18
158
1.14
0.16
1.2
1.2
—
—
nmol/l
—
0
0
8
71
1.13
0.16
1.4
1.2
5.8
6.7
mmol/l
—
8
64
8
72
1.11
0.16
1.5
1.3
4.6
6.1
u/l
—
8
62
13
111
1.17
0.15
1.8
1.6
—
—
—
0
0
8
73
1.10
0.15
1.0
1.3
—
—
—
0
0
103
986
1.05
0.15
3.6
3.9
0.5
1.0
%
1.66
22
226
30
274
1.10
0.15
1.1
1.0
0.2
1.5
u/ml
—
8
58
33
303
1.09
0.15
1.1
1.1
3.9
3.7
u/ml
0.05
16
153
16
140
1.14
0.15
1.3
1.5
—
—
—
0
0
49
459
1.07
0.14
1.3
1.3
—
—
—
0
0
25
227
1.10
0.14
1.2
1.2
277.7
255.9
u/ml
0.16
19
142
31
285
1.09
0.14
1.1
1.1
0.4
0.8
u/ml
0.60
14
118
36
334
1.08
0.13
1.2
1.1
1.8
1.4
u/ml
0.09
12
117
89
928
0.96
0.13
3.4
3.0
1.2
1.2
mmol/l
0.60
76
792
13
113
1.15
0.13
1.9
2.0
31.2
31.1
pg
0.00
13
113
338
3320
1.02
0.13
4.3
3.7
0.0
0.0
estimate
1.08
119
1164
16
179
0.89
0.12
3.8
2.7
—
—
—
0
0
13
114
1.14
0.11
1.2
1.1
—
—
—
0
0
116
1196
0.97
0.11
1.4
1.4
—
—
—
0
0
13
115
1.13
0.10
1.0
1.1
—
—
—
0
0
52
496
1.05
0.10
2.2
3.2
5.1
5.2
kpa
0.15
45
467
43
409
1.05
0.09
1.1
1.2
—
—
—
0
0
19
175
1.09
0.08
2.6
2.2
18.3
16.4
%
—
7
80
28
263
1.07
0.08
1.6
2.4
278.1
199.1
ug/l
0.25
23
231
21
226
0.93
0.08
1.7
2.1
—
—
—
0
0
5
62
0.81
0.08
1.0
1.1
—
—
—
0
0
7
81
0.86
0.07
1.9
2.9
—
—
—
0
0
8
91
0.88
0.06
1.6
1.8
—
—
—
0
0
8
90
0.89
0.06
1.3
1.3
—
—
—
0
0
34
325
1.05
0.06
5.2
4.3
—
—
—
0
0
51
493
1.04
0.06
2.2
3.2
7.5
7.4
ph
—
6
62
151
1486
1.02
0.06
1.6
2.0
29.0
29.2
s
0.17
145
1433
17
182
0.93
0.05
4.9
3.9
—
—
—
0
0
12
130
0.92
0.04
1.2
1.4
—
—
—
0
0
22
231
0.95
0.04
3.6
3.4
20.7
21.0
mg/l
0.01
14
146
19
180
1.06
0.04
1.3
1.2
—
0.4
nmol/l
—
0
8
12
111
1.08
0.04
1.3
1.3
—
—
—
0
0
113
1114
1.02
0.04
1.7
1.7
—
—
—
0
0
11
119
0.92
0.04
1.1
1.2
21.0
33.0
mg/l
2.32
11
94
21
200
1.05
0.03
4.9
2.8
3.3
2.6
mmol/l
0.30
11
135
14
131
1.07
0.03
1.1
1.1
—
—
—
0
0
19
181
1.05
0.03
1.3
2.5
—
—
—
0
0
35
341
1.03
0.02
3.1
3.2
23.7
528.2
u/ml
0.67
27
291
19
198
0.96
0.02
1.2
1.1
0.0
0.0
u/ml
—
5
38
24
232
1.04
0.02
1.0
1.1
2.5
2.1
u/ml
0.15
14
122
89
881
1.01
0.01
5.1
3.2
—
—
—
0
0
11
114
0.96
0.00
1.5
1.6
280.2
277.9
mosm/kgh2o
0.11
11
91
18
176
1.02
0.00
1.1
1.4
—
—
—
0
0
18
176
1.02
0.00
2.2
1.6
—
—
—
0
0
12
122
0.98
0.00
1.4
1.2
0.3
0.9
u/ml
—
6
38
13
128
1.02
0.00
1.0
1.6
—
—
—
0
0
25
251
1.00
0.00
1.1
1.2
—
—
—
0
0
41
413
0.99
0.00
10.6
8.2
—
—
—
0
0
154
1543
1.00
0.00
1.3
1.3
—
—
—
0
0
318
3175
1.00
0.00
2.7
3.0
7.2
6.9
mmol/l
0.50
260
2714
10
95
1.05
0.00
2.3
2.2
—
—
—
0
0
24
245
0.98
0.00
1.2
1.0
2.6
3.0
u/ml
—
10
85
23
225
1.02
0.00
1.2
1.1
1.2
4.1
u/ml
1.31
12
82
0
5
0.00
0.00
0.0
2.2
—
3.7
—
0
5
0
5
0.00
0.00
0.0
6.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
33
330
1.00
0.00
1.5
1.4
37.9
26.7
u/l
0.72
28
284
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
9
97
0.93
0.00
6.3
6.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
426.9
—
0
8
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
63
0.95
0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
206.3
—
0
7
0
6
0.00
0.00
0.0
1.8
—
12.3
—
0
6
9
90
1.00
0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.3
1.0
648.8
769.3
ng/l
—
6
43
5
59
0.85
0.00
1.4
1.6
—
—
—
0
0
6
63
0.95
0.00
1.3
1.0
293.0
358.8
ng/l
—
6
44
10
100
1.00
0.00
2.6
2.2
—
—
—
0
0
5
49
1.02
0.00
4.2
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
0.00
1.0
1.8
13.2
11.1
%
—
5
59
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_BARTHOCYS and mortality.

Females

Parameter HR [95% CI] p-value
N14_BARTHOCYS 0.911 [0.78, 1.06] 0.228
Birth year 0.997 [0.99, 1.01] 0.514

During the follow-up period (1.1.1998 — 31.12.2019), 271 out of 6518 females with N14_BARTHOCYS died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_BARTHOCYS.

N-year risk Females Males
1 0.088% No data
5 0.474% No data
10 1.323% No data
15 2.564% No data
20 4.899% No data

Relationships between endpoints

Index endpoint: N14_BARTHOCYS – Cyst of Bartholin Gland

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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