No definition available.
Congenital malformations of cardiac chambers and connections
Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
228 |
4. Check minimum number of eventsNone |
228 |
5. Include endpointsNone |
228 |
6. Filter based on genotype QC (FinnGen only) |
213 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_CIRCULATO_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q2
- Name in latin
- Malformationes congenitae loculorum et connectionum cordis
Similar endpoints
↥List of similar endpoints to
Congenital malformations of cardiac chambers and connections
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of heart and great arteries
- Congenital malformations of the circulatory system
- Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly
- Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly
- Congenital malformations, deformations and chromosomal abnormalities
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1715 | 717 | 996 |
| Only index persons | 1148 | 491 | 657 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.03 |
| Only index persons | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 2.36 | 3.16 | 1.67 |
| Only index persons | 8.28 | 9.82 | 7.14 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 213 | 89 | 124 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 8.77 | 9.12 | 8.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 228
- Matched controls
- 2280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
201
Kela drug reimbursment
Chronic cardiac insufficiency
241.9
263.5
128
12
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
123.4
238.9
127
23
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
199.2
237.3
117
12
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
52.7
210.5
153
85
XF404
NOMESCO Finland
Ambulatory ECG
64.2
209.2
131
47
XF402
NOMESCO Finland
ECG with work load test
81.2
191.5
108
25
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
148.0
178.5
90
10
B01AA03
ATC
warfarin; systemic
55.5
174.8
109
37
C03CA01
ATC
furosemide; systemic
36.6
167.0
128
77
C03DA01
ATC
spironolactone; oral
48.7
164.1
106
40
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
+∞
139.3
119
*
XF400
NOMESCO Finland
ECG with 12 standard connections
21.9
130.3
150
184
TPH07
NOMESCO Finland
Cathetrisation of artery
25.4
126.7
108
78
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
25.0
122.6
104
74
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
18.1
114.0
138
178
ZXE20
NOMESCO Finland
More than three and less than five hours
18.3
109.4
117
124
FM2CE, ,
NOMESCO Finland
27.2
107.9
83
47
GD1AA
NOMESCO Finland
Thorax X-ray examination
13.9
82.8
173
421
ZXE30
NOMESCO Finland
More than five and less than seven hours
20.2
82.2
71
50
Z2221
NOMESCO Finland
Medical doctor
12.8
80.7
166
394
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
192.4
77.6
77
6
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
17.9
76.1
70
55
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
11.7
76.0
108
163
ZXD10
NOMESCO Finland
Scheduled procedure
13.5
74.6
181
507
C01AA05
ATC
digoxin; systemic
120.6
71.1
74
9
C09AA02
ATC
enalapril; systemic
17.3
64.7
59
45
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
63.6
58
*
XF600
NOMESCO Finland
Bloodpressure measurement
11.3
63.6
83
110
ZXE40
NOMESCO Finland
More than seven and less than nine hours
27.8
63.1
45
20
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
172.9
62.5
63
5
207
Kela drug reimbursment
Chronic arrhythmias
24.8
61.6
46
23
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
61.3
56
*
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
60.1
55
*
ZXE10
NOMESCO Finland
More than one and less than three hours
8.8
59.2
155
443
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
15.2
58.1
57
49
Q20.48
ICD-10 Finland
Single ventricle
+∞
57.8
53
*
31
HP
Congenital heart failure surgery
+∞
56.7
52
*
WX408
NOMESCO Finland
General anesthesy, balanced
7.9
54.7
143
401
I48
ICD-10 Finland
Atrial fibrillation and flutter
18.2
54.4
47
32
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
54.4
50
*
61
HP
Catheterization and pressure measurement of the left side of the heart
326.4
52.4
51
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
87.7
49.7
54
8
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
47.6
44
*
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
286.4
46.9
46
*
I50.9
ICD-10 Finland
Heart failure, unspecified
22.3
46.7
36
19
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
+∞
46.5
43
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
10.1
45.2
59
76
WX404
NOMESCO Finland
Intravenous generell anesthesy
6.5
44.9
118
321
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
68.8
43.5
49
9
R4110
NOMESCO Finland
Physiotherapy
6.3
42.9
131
405
62
HP
Catheterization and pressure measurement of the right side of the heart
492.3
42.6
41
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
492.3
42.6
41
*
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
170.6
41.3
42
*
ZXD05
NOMESCO Finland
Urgent procedure
6.0
41.1
124
377
G04BE03
ATC
sildenafil; oral
233.9
39.1
39
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
+∞
37.5
35
*
WX882
NOMESCO Finland
High dependency care
7.5
36.4
62
108
WX892
NOMESCO Finland
Monitored bed care
8.0
35.6
56
89
Z98.8
ICD-10 Finland
Other specified postsurgical states
+∞
35.3
33
*
I47.1
ICD-10 Finland
Supraventricular tachycardia
12.1
35.2
38
37
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
34.2
32
*
ZXE00
NOMESCO Finland
One hour or less
5.3
33.3
153
632
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
+∞
33.1
31
*
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
33.1
31
*
TFP20
NOMESCO Finland
Cardiodefibrillation
40.1
32.2
40
12
Q21.30
ICD-10 Finland
Tetralogy of Fallot
+∞
32.0
30
*
7451A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[TRANSPOSITIO CORDIS COMPLETA]
+∞
32.0
30
*
Z3231
NOMESCO Finland
Registered nurse
5.0
32.0
135
517
ZX120
NOMESCO Finland
Intravenous
7.2
31.4
54
94
C07AB07
ATC
bisoprolol; oral
5.3
31.3
85
228
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
76.7
29.8
33
5
C01BD01
ATC
amiodarone; systemic
63.9
29.0
33
6
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
28.8
27
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
+∞
28.8
27
*
C09AA05
ATC
ramipril; oral
7.3
27.4
45
74
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
46.1
26.6
32
8
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
+∞
26.6
25
*
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
25.5
24
*
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
25.5
24
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
79.3
25.4
28
*
I49.5
ICD-10 Finland
Sick sinus syndrome
63.5
24.6
28
5
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
+∞
24.4
23
*
WX704
NOMESCO Finland
Intubation
7.5
24.3
38
59
TPH04
NOMESCO Finland
Cathetrisation of vein
4.7
24.2
73
209
C07AB02
ATC
metoprolol; systemic
6.7
23.4
41
72
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
23.3
22
*
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
+∞
22.2
21
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
+∞
22.2
21
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
+∞
21.2
20
*
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
21.2
20
*
Q20.00
ICD-10 Finland
Common arterial trunk
+∞
21.2
20
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.3
21.1
70
213
Z3226
NOMESCO Finland
Physiotherapist
3.9
21.0
90
329
C07AA07
ATC
sotalol; systemic
36.4
20.7
26
8
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.1
20.1
72
231
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
+∞
20.1
19
*
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
19.0
18
*
WX872
NOMESCO Finland
Intensive care
18.3
18.9
29
18
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
109.1
18.9
20
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
8.7
18.7
25
32
WX402
NOMESCO Finland
General anaesthesia
3.6
18.7
91
358
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.0
18.5
68
221
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
25.3
18.2
25
11
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
+∞
17.9
17
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
+∞
17.9
17
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
+∞
17.9
17
*
7AX01, ,
NOMESCO Finland
103.2
17.8
19
*
R07.4
ICD-10 Finland
Chest pain, unspecified
4.0
17.5
60
185
ZX199
NOMESCO Finland
Other rote
34.6
17.4
22
7
I44.2
ICD-10 Finland
Atrioventricular block, complete
68.7
17.0
19
*
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
16.9
16
*
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
+∞
16.9
16
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
+∞
16.9
16
*
FDB20
NOMESCO Finland
Arterial switch operation for other congenital heart defect
+∞
16.9
16
*
Q22.41
ICD-10 Finland
Tricuspid atresia
+∞
16.9
16
*
205
Kela drug reimbursment
Chronic hypertension
6.1
16.7
31
57
602
Kela drug reimbursment
Children's severe malnutrition
7.0
16.2
26
41
R04.0
ICD-10 Finland
Epistaxis
7.5
16.0
24
35
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
+∞
15.8
15
*
Q21.21
ICD-10 Finland
Atrioventricular duct
+∞
15.8
15
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
15.8
15
*
XF620
NOMESCO Finland
Examination of circulation with color method
91.5
15.8
17
*
Z2446
NOMESCO Finland
Social worker
3.7
15.5
62
211
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
60.9
15.0
17
*
I50.0
ICD-10 Finland
Congestive heart failure
27.2
15.0
20
8
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
+∞
14.7
14
*
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
+∞
14.7
14
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
+∞
14.7
14
*
Q26.1
ICD-10 Finland
Persistent left superior vena cava
+∞
14.7
14
*
Q23.11
ICD-10 Finland
Bicuspid aortic valve
+∞
14.7
14
*
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
+∞
14.7
14
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
159.8
14.6
15
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
4.9
14.4
35
82
B01AB05
ATC
enoxaparin; parenteral
3.8
14.2
51
161
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
6.8
14.0
23
37
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
+∞
13.7
13
*
Q20.9
ICD-10 Finland
Congenital malformation of cardiac chambers and connections, unspecified
+∞
13.7
13
*
AP2
HP
Catheterization of the right side of the heart
+∞
13.7
13
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
13.7
13
*
Q24.0
ICD-10 Finland
Dextrocardia
+∞
13.7
13
*
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
13.7
13
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
27.7
13.6
18
7
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
30.4
13.2
17
6
Z94.1
ICD-10 Finland
Heart transplant status
30.4
13.2
17
6
XF640, ,
NOMESCO Finland
30.4
13.2
17
6
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
15.3
13.0
21
15
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
53.2
13.0
15
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
9.9
12.6
25
28
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
+∞
12.6
12
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
+∞
12.6
12
*
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
+∞
12.6
12
*
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
+∞
12.6
12
*
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
12.6
12
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
+∞
12.6
12
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
12.6
12
*
1EA01, ,
NOMESCO Finland
+∞
12.6
12
*
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
137.2
12.6
13
*
B34.9
ICD-10 Finland
Viral infection, unspecified
4.5
12.4
33
83
RS224, ,
NOMESCO Finland
19.4
12.3
18
10
I50.1
ICD-10 Finland
Left ventricular failure
19.4
12.3
18
10
WX002
NOMESCO Finland
Sedation and analgesia
3.8
12.1
42
129
ZX108
NOMESCO Finland
Inhalation
17.6
11.9
18
11
Z01.8
ICD-10 Finland
Other specified special examinations
3.0
11.8
64
259
Q20.60
ICD-10 Finland
Left isomerism of atrial appendages
+∞
11.6
11
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
11.6
11
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
+∞
11.6
11
*
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
11.6
11
*
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
+∞
11.6
11
*
7453B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Common ventricle[COMMON VENTRICLE]
+∞
11.6
11
*
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
126.1
11.5
12
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
5.4
11.5
24
49
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
45.7
11.0
13
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
45.7
11.0
13
*
XQ903
NOMESCO Finland
Production of other scan or drawing
45.7
11.0
13
*
AN1
HP
Coronary angiography
11.4
11.0
20
19
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.8
10.8
26
60
C02EA02, ,
ATC
63.0
10.7
12
*
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
63.0
10.7
12
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
8.9
10.6
22
27
FM1CD
NOMESCO Finland
Very extensive CT of heart
+∞
10.5
10
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
+∞
10.5
10
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
+∞
10.5
10
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
10.5
10
*
FM1BD
NOMESCO Finland
Extensive CT of heart
+∞
10.5
10
*
AP3
HP
Catheterization of the right and left side of the heart
+∞
10.5
10
*
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
+∞
10.5
10
*
FK1AC
NOMESCO Finland
Right cardioangiography
+∞
10.5
10
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
10.5
10
*
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
10.5
10
*
R50.9
ICD-10 Finland
Fever, unspecified
2.7
10.4
70
317
JDB10
NOMESCO Finland
Percutaneous gastrostomy
15.5
10.2
16
11
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.5
9.8
87
450
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
57.5
9.7
11
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.5
9.5
19
37
UGC02
NOMESCO Finland
Rigid bronchoscopy
18.5
9.5
14
8
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
18.5
9.5
14
8
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
31.5
9.5
12
*
TFP35
NOMESCO Finland
Electroanatomical mapping
22.8
9.5
13
6
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
+∞
9.4
9
*
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
9.4
9
*
Q22.40
ICD-10 Finland
Congenital tricuspid stenosis
+∞
9.4
9
*
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
+∞
9.4
9
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
+∞
9.4
9
*
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
9.4
9
*
74629
ICD-8 Finland
Congenital anomalies of heart, Tetralogy of Fallot
+∞
9.4
9
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
+∞
9.4
9
*
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
9.4
9
*
FFE02
NOMESCO Finland
Percutaneous transluminal atrial septostomy
+∞
9.4
9
*
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
9.4
9
*
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
+∞
9.4
9
*
ZXD20
NOMESCO Finland
Day surgery
3.5
9.3
35
113
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.5
9.2
23
55
R55
ICD-10 Finland
Syncope and collapse
4.1
9.1
26
69
RK260, ,
NOMESCO Finland
25.2
9.0
12
5
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
9.2
9.0
18
21
TFP34
NOMESCO Finland
Electrophysiological investigation
11.4
8.9
16
15
I44.1
ICD-10 Finland
Atrioventricular block, second degree
52.0
8.7
10
*
I48.4
ICD-10 Finland
Atypical atrial flutter
52.0
8.7
10
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
10.7
8.7
16
16
K84
ICPC
Heart disease other
28.7
8.6
11
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
93.4
8.5
9
*
1CX08, ,
NOMESCO Finland
93.4
8.5
9
*
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
93.4
8.5
9
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
8.4
8
*
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
+∞
8.4
8
*
Q20.4
ICD-10 Finland
Double inlet ventricle
+∞
8.4
8
*
FFK20
NOMESCO Finland
Atrio-pulmonary anastomosis
+∞
8.4
8
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
+∞
8.4
8
*
7451X
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[MUU TRANSPOSITIO]
+∞
8.4
8
*
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
8.4
8
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
8.4
8
*
7461A
ICD-9 Finland
Other congenital anomalies of heart, Tricuspid atresia and stenosis, congenital[VITIUM VALVULAE TRICUSPIDALIS CONGENITUM CUM ATRESI]
+∞
8.4
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
8.4
51
217
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.6
8.4
56
250
Z3229
NOMESCO Finland
Other healthcare associate professional
3.2
8.3
35
121
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.1
8.3
18
38
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
18.0
8.2
12
7
WX740
NOMESCO Finland
Nitrogen oxide therapy
34.7
8.1
10
*
GD1LA
NOMESCO Finland
GD
34.7
8.1
10
*
ZXA00
NOMESCO Finland
Right side
2.8
8.1
48
201
127
Kela drug reimbursment
Transplant complication
6.8
7.9
19
30
I47.2
ICD-10 Finland
Ventricular tachycardia
15.7
7.8
12
8
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
46.6
7.8
9
*
WX870
NOMESCO Finland
Other postsurgical intensive care
46.6
7.8
9
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
10.6
7.6
14
14
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
82.7
7.5
8
*
R18
ICD-10 Finland
Ascites
82.7
7.5
8
*
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
82.7
7.5
8
*
5401
FHL
Pacemaker installation, transvenous electrode
82.7
7.5
8
*
FL1AC
NOMESCO Finland
Left cardioangiography
82.7
7.5
8
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
82.7
7.5
8
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
9.9
7.4
14
15
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.2
7.3
31
107
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.0
7.3
35
130
Q21.3
ICD-10 Finland
Tetralogy of Fallot
+∞
7.3
7
*
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
+∞
7.3
7
*
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
7.3
7
*
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
+∞
7.3
7
*
AP1
HP
Catheterization of the left side of the heart
+∞
7.3
7
*
AF1
HP
Surgery of congenital heart defect
+∞
7.3
7
*
FGD00
NOMESCO Finland
Repair of tricuspid valve using suture
+∞
7.3
7
*
Q20.41
ICD-10 Finland
Double inlet right ventricle
+∞
7.3
7
*
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
+∞
7.3
7
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
7.3
7
*
7460B
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITUM CUM ATRESIA]
+∞
7.3
7
*
7452A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Tetralogy of Fallot[TETRALOGIA FALLOT]
+∞
7.3
7
*
73
HP
Initial pacemaker installation
+∞
7.3
7
*
5233
FHL
Right ventricular bypass surgery (Fontan et al.)
+∞
7.3
7
*
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
+∞
7.3
7
*
K99
ICPC
Cardiovascular disease other
31.1
7.2
9
*
3A019, ,
NOMESCO Finland
31.1
7.2
9
*
3A077, ,
NOMESCO Finland
31.1
7.2
9
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.2
7.2
79
438
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.3
7.2
28
92
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.2
7.0
19
48
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
7.0
100
615
R06.0
ICD-10 Finland
Dyspnoea
2.6
6.9
47
210
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.1
6.9
19
49
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.1
6.9
19
49
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
17.3
6.8
10
6
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
17.3
6.8
10
6
71
HP
Electrophysiological Special Examination
41.3
6.8
8
*
L04AD02
ATC
tacrolimus; systemic
7.2
6.6
15
22
RD210, ,
NOMESCO Finland
3.5
6.6
23
70
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
3.6
6.6
22
65
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.0
6.5
30
109
5253
FHL
Cardiac lung machine
71.8
6.5
7
*
J96.1
ICD-10 Finland
Chronic respiratory failure
14.9
6.5
10
7
AA1AD
NOMESCO Finland
CT of head and brain
2.7
6.4
36
146
C10AA03
ATC
pravastatin; oral
11.5
6.4
11
10
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.4
6.3
23
72
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.8
6.3
20
57
3AC01, ,
NOMESCO Finland
18.7
6.3
9
5
FN1AD
NOMESCO Finland
CT of coronary arteries
18.7
6.3
9
5
7452B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Tetralogy of Fallot[DOUBLE OUTLET RIGHT VENTRICLE AND PULMONAL STENOSIS]
+∞
6.3
6
*
3A566, ,
NOMESCO Finland
+∞
6.3
6
*
FBJ00
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery
+∞
6.3
6
*
Q22.2
ICD-10 Finland
Congenital pulmonary valve insufficiency
+∞
6.3
6
*
51
HP
Other heart surgery
+∞
6.3
6
*
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
+∞
6.3
6
*
90492, ,
NOMESCO Finland
+∞
6.3
6
*
Q22.6
ICD-10 Finland
Hypoplastic right heart syndrome
+∞
6.3
6
*
Q25.3
ICD-10 Finland
Stenosis of aorta
+∞
6.3
6
*
FMC96
NOMESCO Finland
Other operation on aortic valve for insufficiency
+∞
6.3
6
*
FJD96
NOMESCO Finland
Other operation on right ventricle outlet for congenital or acquired obstruction
+∞
6.3
6
*
3A064, ,
NOMESCO Finland
+∞
6.3
6
*
XFP02, ,
NOMESCO Finland
+∞
6.3
6
*
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
+∞
6.3
6
*
74637
ICD-8 Finland
Congenital anomalies of heart, Cor triloculare biatriatum (""""single ventricles"""")
+∞
6.3
6
*
I97.0
ICD-10 Finland
Postcardiotomy syndrome
+∞
6.3
6
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
6.3
6
*
5409
FHL
Other measure in this category
+∞
6.3
6
*
7468X
ICD-9 Finland
Other congenital anomalies of heart, Other specified anomalies of heart[MUU SYDÄMEN EPÄMUODOSTUMA]
+∞
6.3
6
*
324, ,
NOMESCO Finland
27.5
6.3
8
*
TFJ02
NOMESCO Finland
Muscle biopsy of heart
27.5
6.3
8
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.0
6.2
18
48
XG460
NOMESCO Finland
Short time oxymetry
13.0
6.1
10
8
TK800
NOMESCO Finland
Hemodialysis
9.0
6.1
12
14
L04AA06
ATC
mycophenolic acid; systemic
6.3
6.1
15
25
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.5
6.1
40
176
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.2
6.0
16
40
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
156
51
94.70
260.10
6.8
6.9
155.83
164.93
ng/l
0.05
147
45
62
33
25.43
81.72
4.0
6.1
73.21
100.79
%
3.37
62
33
119
189
12.08
81.03
7.7
3.3
3164.54
211.56
ng/l
2.18
104
101
161
404
11.16
72.85
29.0
6.3
2.04
1.10
inr
8.51
33
125
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
56
35
20.88
68.17
17.5
20.2
0.31
0.30
u/ml
0.10
40
22
73
100
10.27
53.87
5.8
8.5
178.62
168.25
%
0.43
73
100
102
208
8.06
53.28
3.8
3.1
20.51
23.90
%
1.59
93
198
103
225
7.53
49.96
4.0
3.0
2.47
2.54
g/l
0.59
103
217
128
347
7.13
49.79
4.2
3.4
—
—
—
0
0
142
430
7.10
48.94
14.1
8.4
66.80
90.72
%
22.05
142
424
41
39
12.60
38.67
1.5
1.5
—
—
—
0
0
102
297
5.41
34.51
5.7
4.6
1.89
1.23
mg/l
0.94
77
216
102
298
5.38
34.35
5.6
2.9
34.40
24.58
ng/l
0.38
63
139
148
617
4.99
31.20
4.8
3.4
—
—
—
0
0
107
395
4.22
25.37
3.9
3.6
3.55
2.60
mg/l
1.17
100
349
63
165
4.89
23.23
16.3
13.5
106.51
105.32
mmol/l
1.37
63
165
50
112
5.44
22.06
29.9
17.9
0.09
0.28
mmol/l
0.11
45
95
221
1655
11.92
20.29
40.5
13.5
139.19
139.51
mmol/l
1.43
221
1603
221
1655
11.92
20.29
40.6
13.5
4.03
3.96
mmol/l
2.63
221
1597
38
77
5.72
18.57
37.7
17.8
0.66
0.73
%
0.72
38
77
38
77
5.72
18.57
37.7
17.8
1.09
1.20
%
0.47
38
77
88
371
3.23
15.70
26.4
16.5
25.47
24.63
mmol/l
1.61
88
371
83
344
3.22
15.16
9.4
11.3
1.11
1.14
mmol/l
0.03
71
267
55
184
3.62
14.05
2.9
1.8
—
—
—
0
0
54
184
3.54
13.37
3.2
1.9
—
—
—
0
0
79
340
3.03
13.28
20.0
10.3
1.80
0.87
mmol/l
2.37
67
253
79
342
3.00
13.12
20.2
10.2
5.16
5.08
kpa
0.56
79
331
74
313
3.02
12.76
8.5
11.3
23.62
23.34
mmol/l
0.46
74
313
72
301
3.03
12.66
20.2
10.4
8.70
9.70
kpa
2.72
72
290
30
69
4.86
12.58
8.1
16.9
0.69
0.54
%
1.56
30
69
59
230
3.11
11.62
3.3
2.0
—
—
—
0
0
23
45
5.57
11.53
7.7
20.9
75.63
72.40
%
0.43
23
45
13
5
27.41
9.92
2.9
13.6
—
—
—
0
0
20
41
5.25
9.50
2.2
2.6
1.04
1.09
g/l
0.09
15
36
15
11
14.49
9.32
1.7
2.2
170.33
127.82
%
1.33
15
11
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
16
15
11.37
8.94
1.6
2.0
129.13
125.13
%
0.07
16
15
21
48
4.72
8.82
2.2
2.0
—
—
—
0
0
161
1155
2.34
7.88
23.3
7.9
101.08
101.06
ml/min/173m2
0.00
136
848
24
70
3.71
7.34
2.7
2.2
—
—
—
0
0
62
315
2.33
6.92
5.0
2.3
473.97
342.96
u/l
0.35
62
310
20
54
3.96
6.80
1.5
5.1
—
—
—
0
0
21
59
3.82
6.77
2.1
2.1
—
—
—
0
0
11
9
12.76
6.65
1.6
1.6
13.00
10.22
umol/l
—
11
9
11
9
12.76
6.65
1.1
1.1
80.27
105.56
%
—
11
9
156
1157
2.10
6.30
13.4
13.0
3.73
3.62
e9/l
0.30
147
966
23
73
3.39
6.21
4.1
2.4
68.30
88.15
ml/min/173m2
—
10
27
23
73
3.39
6.21
2.7
2.5
—
—
—
0
0
214
1829
3.77
6.16
30.4
11.6
24.17
21.97
mg/l
0.49
176
1277
19
58
3.48
5.44
2.8
2.3
—
—
—
0
0
19
58
3.48
5.44
2.8
2.3
—
—
—
0
0
18
53
3.60
5.43
1.4
5.1
14.67
9.09
%
1.13
18
53
16
34
4.98
5.42
1.4
1.2
1.50
1.56
u/ml
—
6
16
16
34
4.98
5.42
1.4
1.2
7.00
2.87
u/ml
—
8
16
12
18
6.97
5.33
1.2
1.2
80.58
94.94
%
0.52
12
18
23
82
3.01
5.15
2.5
1.5
—
—
—
0
0
8
6
13.75
5.11
1.4
1.2
—
—
—
0
0
17
51
3.52
4.99
2.1
2.2
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
10
14
7.41
4.70
2.3
1.1
57.00
119.36
%
—
10
14
12
22
5.69
4.67
2.3
2.2
—
—
—
0
0
14
31
4.74
4.64
1.3
1.2
—
—
—
0
0
16
50
3.37
4.43
2.9
2.3
—
—
—
0
0
16
50
3.37
4.43
2.9
2.3
—
—
—
0
0
87
578
1.82
4.38
4.8
4.6
—
—
—
0
0
5
211
0.22
4.24
1.0
1.1
—
—
—
0
0
19
70
2.87
4.03
16.4
11.7
1796.00
425.33
iu/ml
—
5
12
16
54
3.11
3.93
1.3
4.7
0.26
0.16
e9/l
0.65
11
38
77
507
1.78
3.92
4.7
4.3
0.50
0.26
e6/l
0.66
58
376
11
23
4.97
3.92
1.7
1.4
—
—
—
0
0
57
343
1.88
3.87
2.9
3.9
2.17
1.55
e6/l
0.30
30
206
15
50
3.14
3.76
1.3
4.9
13.87
27.74
%
5.32
15
50
19
73
2.75
3.74
1.8
1.3
—
—
—
0
0
19
73
2.75
3.74
1.8
1.3
—
—
—
0
0
23
100
2.45
3.56
1.8
1.8
—
—
—
0
0
21
89
2.50
3.43
3.0
2.7
—
—
—
0
0
55
340
1.81
3.41
3.1
3.8
0.55
0.57
e6/l
0.03
28
202
23
103
2.37
3.35
1.6
1.9
—
—
—
0
0
15
54
2.90
3.32
14.1
5.6
53.11
63.18
%
0.62
15
54
9
19
4.88
3.27
8.2
12.4
2.55
2.53
mg/l
—
9
14
11
29
3.93
3.23
1.3
1.4
—
—
—
0
0
16
63
2.66
3.03
9.3
12.6
—
2462.30
—
0
10
9
21
4.42
3.02
1.4
1.8
—
—
—
0
0
161
1825
0.60
2.95
3.9
3.9
—
—
—
0
0
12
38
3.28
2.90
1.7
1.6
—
—
—
0
0
48
716
0.58
2.81
1.5
1.8
0.30
2.98
u/ml
—
6
133
17
72
2.47
2.80
2.4
1.4
—
—
—
0
0
5
6
8.48
2.76
1.4
1.8
—
—
—
0
0
22
107
2.17
2.67
2.8
1.9
—
—
—
0
0
13
49
2.75
2.67
1.4
1.7
—
—
—
0
0
8
20
4.11
2.59
1.5
1.7
—
—
—
0
0
10
31
3.33
2.55
1.9
5.3
56.30
49.29
%
—
10
31
7
16
4.48
2.49
2.6
1.5
—
—
—
0
0
11
39
2.91
2.38
1.9
2.0
—
—
—
0
0
6
13
4.71
2.28
1.8
1.8
—
—
—
0
0
0
57
0.00
2.08
0.0
1.9
—
—
—
0
0
12
52
2.38
1.91
2.0
1.8
—
—
—
0
0
5
12
4.23
1.83
2.4
1.4
—
—
—
0
0
17
89
1.98
1.75
9.1
4.0
—
—
—
0
0
0
48
0.00
1.72
0.0
1.2
—
—
—
0
0
5
14
3.63
1.62
1.6
2.0
—
—
—
0
0
5
14
3.63
1.62
1.6
2.0
—
—
—
0
0
5
14
3.63
1.62
1.6
2.0
—
—
—
0
0
8
32
2.55
1.61
2.1
3.2
141.13
129.54
g/l
—
8
26
16
85
1.95
1.59
1.3
1.4
—
—
—
0
0
10
47
2.18
1.35
1.0
1.0
156.20
163.74
g/l
—
10
47
5
118
0.41
1.29
1.2
1.4
—
—
—
0
0
8
36
2.27
1.25
3.0
4.8
20.76
15.66
u/ml
—
8
36
6
25
2.44
1.25
5.0
6.3
—
—
—
0
0
11
57
1.98
1.19
1.1
3.4
—
—
—
0
0
0
35
0.00
1.16
0.0
1.1
—
—
—
0
0
0
35
0.00
1.16
0.0
1.1
—
—
—
0
0
0
35
0.00
1.16
0.0
1.1
—
—
—
0
0
12
65
1.89
1.15
1.5
1.2
—
—
—
0
0
7
31
2.30
1.11
1.4
1.5
—
—
—
0
0
6
124
0.47
1.08
1.2
2.0
—
—
—
0
0
18
115
1.61
1.03
2.3
2.1
—
—
—
0
0
5
23
2.20
0.98
1.6
2.2
0.00
0.00
g/l
—
5
23
5
23
2.20
0.98
1.6
2.2
0.00
0.00
g/l
—
5
23
12
70
1.75
0.94
4.6
3.8
1.26
1.23
mmol/l
0.79
12
57
10
168
0.58
0.91
1.4
1.5
—
—
—
0
0
6
29
2.10
0.90
2.2
1.8
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
0
26
0.00
0.79
0.0
1.6
—
—
—
0
0
0
27
0.00
0.78
0.0
1.3
—
—
—
0
0
24
176
1.41
0.76
3.4
2.8
31.95
33.05
u/l
0.05
19
148
9
54
1.69
0.75
2.7
1.8
—
—
—
0
0
5
24
2.11
0.75
1.6
2.2
0.00
0.00
g/l
—
5
24
5
26
1.94
0.71
1.6
2.1
—
—
—
0
0
5
28
1.80
0.66
1.8
1.8
—
—
—
0
0
8
131
0.60
0.65
1.0
1.2
—
—
—
0
0
10
153
0.64
0.65
1.4
1.3
85.86
166.31
iu/ml
—
5
51
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
43
511
0.80
0.60
4.3
3.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
117
1259
0.85
0.54
3.4
2.8
5.49
5.58
mmol/l
0.55
110
1168
18
234
0.75
0.51
1.2
1.3
9.98
18.89
iu/ml
—
6
60
8
116
0.68
0.47
1.1
1.3
—
—
—
0
0
14
184
0.75
0.43
2.0
2.1
13.20
12.50
nmol/l
0.11
14
172
5
33
1.53
0.41
5.8
4.9
22.00
27.30
umol/l
—
5
33
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
73.98
—
0
10
0
16
0.00
0.41
0.0
1.5
—
12.60
—
0
5
0
16
0.00
0.41
0.0
7.0
—
—
—
0
0
0
16
0.00
0.41
0.0
7.0
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
0.71
—
0
10
0
17
0.00
0.41
0.0
1.1
—
2.33
—
0
11
0
17
0.00
0.41
0.0
1.1
—
223.70
—
0
17
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
26
215
1.24
0.40
1.2
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
3.1
—
757.67
—
0
18
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
36
415
0.84
0.38
1.8
2.2
—
—
—
0
0
134
1273
1.13
0.36
4.3
3.0
1.26
1.26
mmol/l
0.03
127
1210
6
41
1.48
0.36
2.2
2.3
—
—
—
0
0
17
209
0.80
0.34
1.7
1.8
—
—
—
0
0
11
140
0.77
0.29
1.2
1.2
—
—
—
0
0
27
235
1.17
0.27
3.3
2.8
353.04
337.64
nmol/l
0.15
27
222
6
82
0.72
0.24
1.0
1.6
—
—
—
0
0
5
39
1.29
0.23
1.8
2.0
—
—
—
0
0
13
156
0.82
0.22
1.3
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
26.89
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
2.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
2.03
—
0
8
40
366
1.11
0.20
1.9
1.6
86.70
96.48
pmol/l
0.81
24
195
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
22
246
0.88
0.17
1.6
2.0
—
—
—
0
0
5
67
0.74
0.17
1.0
1.7
—
—
—
0
0
5
69
0.72
0.17
2.4
2.4
1.75
0.43
nmol/l
—
5
60
42
450
0.92
0.16
1.9
2.4
—
—
—
0
0
6
79
0.75
0.16
1.8
1.3
44.83
31.93
nmol/l
—
6
79
37
344
1.09
0.14
4.1
3.6
0.15
0.00
estimate
0.47
13
123
136
1331
1.05
0.12
4.3
3.2
2.59
2.81
mmol/l
1.99
130
1260
135
1324
1.05
0.10
4.3
3.1
1.20
1.38
mmol/l
7.64
130
1258
149
1515
0.95
0.10
4.7
4.0
2.22
1.89
mu/l
1.84
142
1424
74
761
0.96
0.08
4.1
3.4
0.00
0.00
estimate
-0.00
12
118
7
68
1.03
0.08
1.0
1.1
—
—
—
0
0
128
1301
0.96
0.07
4.2
3.7
15.70
14.37
pmol/l
6.29
121
1208
10
112
0.89
0.07
1.7
1.6
—
—
—
0
0
7
80
0.87
0.07
1.6
1.4
—
—
—
0
0
7
80
0.87
0.07
1.6
1.4
—
—
—
0
0
7
80
0.87
0.07
1.6
1.4
—
—
—
0
0
9
87
1.04
0.07
1.3
1.6
—
—
—
0
0
16
172
0.92
0.06
1.6
2.7
0.53
1.18
ug/l
5.23
11
160
74
755
0.97
0.05
5.7
5.0
0.00
0.00
estimate
-0.00
14
127
23
239
0.96
0.03
4.0
4.6
25.28
17.25
mg/mmol
0.28
18
175
74
750
0.98
0.02
1.9
1.9
—
—
—
0
0
116
1150
1.02
0.02
4.0
3.8
35.19
37.80
mmol/mol
4.26
111
1098
75
756
0.99
0.00
4.1
3.4
0.00
0.00
estimate
-0.00
14
126
10
97
1.03
0.00
1.0
1.0
21.60
19.17
mmol/l
—
10
97
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
21.67
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.4
—
4.00
—
0
5
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.94
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
14.42
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
74.00
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
70
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
18.34
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO | 9.355 [4.38, 19.97] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.586 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 576 females with Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO | 7.222 [4.72, 11.04] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 760 males with Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.913% | 1.304% |
| 5 | 6.522% | 6.938% |
| 10 | 15.52% | 17.531% |
| 15 | 25.751% | 31.095% |
| 20 | 40.699% | 46.393% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO – Congenital malformations of cardiac chambers and connections
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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