No definition available.
Congenital malformations of cardiac chambers and connections
Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519870 |
1. Apply sex-specific ruleNone |
519870 |
2. Check conditionsNone |
519870 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
230 |
4. Check minimum number of eventsNone |
230 |
5. Include endpointsNone |
230 |
6. Filter based on genotype QC (FinnGen only) |
213 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_CIRCULATO_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q2
- Name in latin
- Malformationes congenitae loculorum et connectionum cordis
Similar endpoints
↥List of similar endpoints to
Congenital malformations of cardiac chambers and connections
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of heart and great arteries
- Congenital malformations of the circulatory system
- Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly
- Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1715 | 717 | 996 |
| Only index persons | 1148 | 491 | 657 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.03 |
| Only index persons | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 2.36 | 3.16 | 1.67 |
| Only index persons | 8.28 | 9.82 | 7.14 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 213 | 90 | 123 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 8.53 | 9.46 | 7.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 230
- Matched controls
- 2300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
201
Kela drug reimbursment
Chronic cardiac insufficiency
194.6
259.3
129
15
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
131.0
248.2
131
23
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
208.0
244.3
120
12
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
52.2
212.4
157
91
XF404
NOMESCO Finland
Ambulatory ECG
63.4
209.1
131
47
XF402
NOMESCO Finland
ECG with work load test
80.6
191.4
108
25
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
147.2
178.4
90
10
B01AA03
ATC
warfarin; systemic
56.1
176.9
110
37
C03CA01
ATC
furosemide; systemic
38.4
174.0
132
78
C03DA01
ATC
spironolactone; oral
48.1
168.6
110
43
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
+∞
140.4
120
*
TPH07
NOMESCO Finland
Cathetrisation of artery
25.9
132.8
114
84
XF400
NOMESCO Finland
ECG with 12 standard connections
22.0
131.8
152
187
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
25.5
126.5
107
76
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
18.0
114.8
142
189
ZXE20
NOMESCO Finland
More than three and less than five hours
18.5
110.9
118
124
FM2CE, ,
NOMESCO Finland
27.0
108.8
84
48
ZXE30
NOMESCO Finland
More than five and less than seven hours
21.4
86.7
73
49
GD1AA
NOMESCO Finland
Thorax X-ray examination
14.5
81.8
181
468
Z2221
NOMESCO Finland
Medical doctor
12.8
81.4
167
395
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
11.9
78.9
113
173
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
195.3
78.7
78
6
ZXD10
NOMESCO Finland
Scheduled procedure
13.8
76.5
183
507
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
17.3
75.5
71
58
C01AA05
ATC
digoxin; systemic
120.1
71.1
74
9
XF600
NOMESCO Finland
Bloodpressure measurement
11.6
65.9
85
111
C09AA02
ATC
enalapril; systemic
16.9
65.8
61
48
ZXE40
NOMESCO Finland
More than seven and less than nine hours
29.2
64.4
45
19
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
176.2
63.6
64
5
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
63.5
58
*
ZXE10
NOMESCO Finland
More than one and less than three hours
9.1
61.3
157
441
207
Kela drug reimbursment
Chronic arrhythmias
23.4
61.3
47
25
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
61.2
56
*
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
61.2
56
*
Q20.48
ICD-10 Finland
Single ventricle
+∞
60.1
55
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
14.9
58.4
58
51
31
HP
Congenital heart failure surgery
+∞
57.8
53
*
WX408
NOMESCO Finland
General anesthesy, balanced
8.0
55.8
145
405
I50.9
ICD-10 Finland
Heart failure, unspecified
24.7
55.2
41
20
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
54.4
50
*
61
HP
Catheterization and pressure measurement of the left side of the heart
333.9
53.5
52
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
17.6
53.5
47
33
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
87.5
49.7
54
8
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
293.6
47.9
47
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
47.6
44
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
10.3
46.6
60
76
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
+∞
46.4
43
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
72.2
45.6
51
9
R4110
NOMESCO Finland
Physiotherapy
6.5
45.2
137
424
WX404
NOMESCO Finland
Intravenous generell anesthesy
6.5
45.1
119
325
XF622
NOMESCO Finland
Measurement of minute volume of heart
506.2
43.7
42
*
ZXD05
NOMESCO Finland
Urgent procedure
6.3
43.5
126
372
62
HP
Catheterization and pressure measurement of the right side of the heart
491.4
42.6
41
*
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
131.5
41.3
43
*
G04BE03
ATC
sildenafil; oral
233.5
39.1
39
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
+∞
38.6
36
*
WX882
NOMESCO Finland
High dependency care
7.6
37.2
63
109
I47.1
ICD-10 Finland
Supraventricular tachycardia
12.5
36.8
39
37
WX892
NOMESCO Finland
Monitored bed care
8.0
36.1
57
91
Z98.8
ICD-10 Finland
Other specified postsurgical states
+∞
35.3
33
*
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
35.3
33
*
ZXE00
NOMESCO Finland
One hour or less
5.4
34.3
155
634
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
34.2
32
*
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
+∞
33.1
31
*
Z3231
NOMESCO Finland
Registered nurse
5.0
32.6
137
524
Q21.30
ICD-10 Finland
Tetralogy of Fallot
+∞
32.0
30
*
7451A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[TRANSPOSITIO CORDIS COMPLETA]
+∞
32.0
30
*
C07AB07
ATC
bisoprolol; oral
5.3
32.0
89
244
ZX120
NOMESCO Finland
Intravenous
7.1
31.6
55
97
TFP20
NOMESCO Finland
Cardiodefibrillation
36.9
31.6
40
13
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
79.3
30.8
34
5
C09AA05
ATC
ramipril; oral
7.5
29.2
47
76
C01BD01
ATC
amiodarone; systemic
63.8
29.0
33
6
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
28.7
27
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
+∞
28.7
27
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
85.6
27.5
30
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
46.1
26.6
32
8
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
26.6
25
*
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
+∞
26.6
25
*
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
25.5
24
*
I49.5
ICD-10 Finland
Sick sinus syndrome
63.4
24.6
28
5
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
+∞
24.4
23
*
C07AB02
ATC
metoprolol; systemic
6.8
24.2
42
73
WX704
NOMESCO Finland
Intubation
7.0
23.3
39
65
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
23.3
22
*
TPH04
NOMESCO Finland
Cathetrisation of vein
4.5
23.2
74
220
WX402
NOMESCO Finland
General anaesthesia
3.9
22.4
103
397
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
+∞
22.2
21
*
Q20.00
ICD-10 Finland
Common arterial trunk
+∞
22.2
21
*
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
+∞
22.2
21
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
+∞
22.2
21
*
Z3226
NOMESCO Finland
Physiotherapist
3.9
21.6
91
329
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.3
21.5
71
216
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
21.2
20
*
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
+∞
21.2
20
*
C07AA07
ATC
sotalol; systemic
36.4
20.7
26
8
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.9
19.3
73
243
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
19.0
18
*
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
109.0
18.9
20
*
R07.4
ICD-10 Finland
Chest pain, unspecified
4.0
18.6
65
204
WX872
NOMESCO Finland
Intensive care
17.3
18.5
29
19
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
8.4
18.2
25
33
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
25.3
18.2
25
11
I44.2
ICD-10 Finland
Atrioventricular block, complete
72.6
18.0
20
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
+∞
17.9
17
*
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
+∞
17.9
17
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
+∞
17.9
17
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
+∞
17.9
17
*
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
17.9
17
*
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
+∞
17.9
17
*
7AX01, ,
NOMESCO Finland
103.1
17.8
19
*
R04.0
ICD-10 Finland
Epistaxis
7.5
17.8
27
40
ZX199
NOMESCO Finland
Other rote
34.5
17.4
22
7
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
68.7
17.0
19
*
FDB20
NOMESCO Finland
Arterial switch operation for other congenital heart defect
+∞
16.9
16
*
Q22.41
ICD-10 Finland
Tricuspid atresia
+∞
16.9
16
*
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
+∞
16.9
16
*
B01AB05
ATC
enoxaparin; parenteral
4.1
16.6
55
165
205
Kela drug reimbursment
Chronic hypertension
6.0
16.4
31
58
Z2446
NOMESCO Finland
Social worker
3.7
16.1
63
212
Z94.1
ICD-10 Finland
Heart transplant status
36.3
16.0
20
6
602
Kela drug reimbursment
Children's severe malnutrition
6.9
15.8
26
42
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.5
15.8
72
267
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
15.8
15
*
Q21.21
ICD-10 Finland
Atrioventricular duct
+∞
15.8
15
*
Q23.11
ICD-10 Finland
Bicuspid aortic valve
+∞
15.8
15
*
Q26.1
ICD-10 Finland
Persistent left superior vena cava
+∞
15.8
15
*
XF620
NOMESCO Finland
Examination of circulation with color method
91.5
15.8
17
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
171.2
15.7
16
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
+∞
14.7
14
*
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
+∞
14.7
14
*
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
+∞
14.7
14
*
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
+∞
14.7
14
*
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
+∞
14.7
14
*
I50.1
ICD-10 Finland
Left ventricular failure
21.8
14.0
20
10
I50.0
ICD-10 Finland
Congestive heart failure
21.8
14.0
20
10
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
6.8
14.0
23
37
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
57.0
14.0
16
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
13.7
13
*
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
13.7
13
*
Q20.9
ICD-10 Finland
Congenital malformation of cardiac chambers and connections, unspecified
+∞
13.7
13
*
Q24.0
ICD-10 Finland
Dextrocardia
+∞
13.7
13
*
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
13.7
13
*
AP2
HP
Catheterization of the right side of the heart
+∞
13.7
13
*
XF640, ,
NOMESCO Finland
30.4
13.2
17
6
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
24.3
13.1
18
8
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
53.2
13.0
15
*
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
12.8
69
280
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
21.6
12.7
18
9
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
12.7
12.6
22
19
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
+∞
12.6
12
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
+∞
12.6
12
*
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
+∞
12.6
12
*
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
+∞
12.6
12
*
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
+∞
12.6
12
*
1EA01, ,
NOMESCO Finland
+∞
12.6
12
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
12.6
12
*
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
137.2
12.6
13
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
9.5
12.4
25
29
RS224, ,
NOMESCO Finland
19.4
12.3
18
10
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
5.5
12.3
25
50
WX002
NOMESCO Finland
Sedation and analgesia
3.8
12.1
42
129
ZX108
NOMESCO Finland
Inhalation
17.6
11.9
18
11
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
68.5
11.7
13
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
11.6
11
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
+∞
11.6
11
*
7453B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Common ventricle[COMMON VENTRICLE]
+∞
11.6
11
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
11.6
11
*
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
11.6
11
*
Q20.60
ICD-10 Finland
Left isomerism of atrial appendages
+∞
11.6
11
*
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
+∞
11.6
11
*
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
126.1
11.5
12
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
4.0
11.4
35
98
B34.9
ICD-10 Finland
Viral infection, unspecified
4.1
11.1
33
90
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
9.0
11.1
23
28
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
45.7
11.0
13
*
XQ903
NOMESCO Finland
Production of other scan or drawing
45.7
11.0
13
*
AN1
HP
Coronary angiography
11.4
11.0
20
19
C02EA02, ,
ATC
63.0
10.7
12
*
I48.4
ICD-10 Finland
Atypical atrial flutter
63.0
10.7
12
*
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
115.0
10.5
11
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
10.5
10
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
+∞
10.5
10
*
FM1CD
NOMESCO Finland
Very extensive CT of heart
+∞
10.5
10
*
AP3
HP
Catheterization of the right and left side of the heart
+∞
10.5
10
*
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
+∞
10.5
10
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
10.5
10
*
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
10.5
10
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
+∞
10.5
10
*
FM1BD
NOMESCO Finland
Extensive CT of heart
+∞
10.5
10
*
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
+∞
10.5
10
*
FK1AC
NOMESCO Finland
Right cardioangiography
+∞
10.5
10
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
34.3
10.4
13
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.5
10.2
90
464
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.5
10.2
26
63
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.8
10.2
61
259
JDB10
NOMESCO Finland
Percutaneous gastrostomy
15.5
10.2
16
11
R50.9
ICD-10 Finland
Fever, unspecified
2.7
10.1
74
348
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
10.0
55
223
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
11.4
10.0
18
17
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
57.5
9.7
11
*
UGC02
NOMESCO Finland
Rigid bronchoscopy
18.5
9.5
14
8
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
18.5
9.5
14
8
ZXD20
NOMESCO Finland
Day surgery
3.5
9.5
35
111
TFP35
NOMESCO Finland
Electroanatomical mapping
22.8
9.5
13
6
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
9.4
9
*
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
+∞
9.4
9
*
Q22.40
ICD-10 Finland
Congenital tricuspid stenosis
+∞
9.4
9
*
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
+∞
9.4
9
*
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
9.4
9
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
+∞
9.4
9
*
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
9.4
9
*
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
9.4
9
*
FFE02
NOMESCO Finland
Percutaneous transluminal atrial septostomy
+∞
9.4
9
*
74629
ICD-8 Finland
Congenital anomalies of heart, Tetralogy of Fallot
+∞
9.4
9
*
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
9.4
9
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
+∞
9.4
9
*
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
+∞
9.4
9
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.5
9.4
24
58
GD1LA
NOMESCO Finland
GD
38.3
9.1
11
*
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
19.6
9.0
13
7
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.2
9.0
19
39
RK260, ,
NOMESCO Finland
25.2
9.0
12
5
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
11.4
8.9
16
15
TFP34
NOMESCO Finland
Electrophysiological investigation
11.4
8.9
16
15
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
8.9
113
677
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
8.8
36
122
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
8.8
8.8
18
22
I44.1
ICD-10 Finland
Atrioventricular block, second degree
52.0
8.7
10
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
52.0
8.7
10
*
FN1AD
NOMESCO Finland
CT of coronary arteries
21.0
8.6
12
6
R55
ICD-10 Finland
Syncope and collapse
3.8
8.5
27
77
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.0
8.5
19
41
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
93.3
8.5
9
*
1CX08, ,
NOMESCO Finland
93.3
8.5
9
*
FFK20
NOMESCO Finland
Atrio-pulmonary anastomosis
+∞
8.4
8
*
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
+∞
8.4
8
*
7461A
ICD-9 Finland
Other congenital anomalies of heart, Tricuspid atresia and stenosis, congenital[VITIUM VALVULAE TRICUSPIDALIS CONGENITUM CUM ATRESI]
+∞
8.4
8
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
8.4
8
*
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
+∞
8.4
8
*
7451X
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[MUU TRANSPOSITIO]
+∞
8.4
8
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
+∞
8.4
8
*
Q20.4
ICD-10 Finland
Double inlet ventricle
+∞
8.4
8
*
AA1AD
NOMESCO Finland
CT of head and brain
2.9
8.4
44
173
I47.2
ICD-10 Finland
Ventricular tachycardia
15.2
8.3
13
9
ZXA00
NOMESCO Finland
Right side
2.8
8.3
49
205
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
18.0
8.2
12
7
L04AD02
ATC
tacrolimus; systemic
7.7
8.1
18
25
K84
ICPC
Heart disease other
23.0
8.1
11
5
WX870
NOMESCO Finland
Other postsurgical intensive care
46.6
7.8
9
*
FL1AC
NOMESCO Finland
Left cardioangiography
46.6
7.8
9
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
46.6
7.8
9
*
127
Kela drug reimbursment
Transplant complication
6.6
7.7
19
31
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
10.6
7.6
14
14
WX740
NOMESCO Finland
Nitrogen oxide therapy
26.0
7.6
10
*
L04AA06
ATC
mycophenolic acid; systemic
6.9
7.6
18
28
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.0
7.6
22
59
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.3
7.5
20
50
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
82.6
7.5
8
*
5401
FHL
Pacemaker installation, transvenous electrode
82.6
7.5
8
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
82.6
7.5
8
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.2
7.5
31
106
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.0
7.4
35
129
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
+∞
7.3
7
*
AF1
HP
Surgery of congenital heart defect
+∞
7.3
7
*
5233
FHL
Right ventricular bypass surgery (Fontan et al.)
+∞
7.3
7
*
7460B
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITUM CUM ATRESIA]
+∞
7.3
7
*
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
+∞
7.3
7
*
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
7.3
7
*
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
+∞
7.3
7
*
AP1
HP
Catheterization of the left side of the heart
+∞
7.3
7
*
Q20.41
ICD-10 Finland
Double inlet right ventricle
+∞
7.3
7
*
Q21.3
ICD-10 Finland
Tetralogy of Fallot
+∞
7.3
7
*
FJD96
NOMESCO Finland
Other operation on right ventricle outlet for congenital or acquired obstruction
+∞
7.3
7
*
FGD00
NOMESCO Finland
Repair of tricuspid valve using suture
+∞
7.3
7
*
7452A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Tetralogy of Fallot[TETRALOGIA FALLOT]
+∞
7.3
7
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
7.3
7
*
73
HP
Initial pacemaker installation
+∞
7.3
7
*
C09DX04
ATC
valsartan and sacubitril; oral
31.1
7.2
9
*
K99
ICPC
Cardiovascular disease other
31.1
7.2
9
*
3A019, ,
NOMESCO Finland
31.1
7.2
9
*
3A077, ,
NOMESCO Finland
31.1
7.2
9
*
C10AA03
ATC
pravastatin; oral
12.6
7.2
12
10
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
3.6
7.0
24
72
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.2
7.0
19
48
XG460
NOMESCO Finland
Short time oxymetry
14.4
7.0
11
8
TK800
NOMESCO Finland
Hemodialysis
9.8
6.9
13
14
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.1
6.9
19
49
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.1
6.9
19
49
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
17.3
6.8
10
6
K83
ICPC
Heart valve disease NOS
41.3
6.8
8
*
R18
ICD-10 Finland
Ascites
41.3
6.8
8
*
71
HP
Electrophysiological Special Examination
41.3
6.8
8
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.2
6.8
82
471
R00.2
ICD-10 Finland
Palpitations
3.5
6.6
23
70
RD210, ,
NOMESCO Finland
3.5
6.6
23
70
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.1
6.6
28
97
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.0
6.5
30
109
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
6.5
28
98
I48.3
ICD-10 Finland
Typical atrial flutter
71.8
6.5
7
*
5253
FHL
Cardiac lung machine
71.8
6.5
7
*
J96.1
ICD-10 Finland
Chronic respiratory failure
14.9
6.5
10
7
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
14.9
6.5
10
7
3AC01, ,
NOMESCO Finland
18.6
6.3
9
5
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.3
6.3
25
83
TLC00
NOMESCO Finland
Insertion of intrauterine device
4.2
6.3
17
43
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
4.2
6.3
17
43
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
+∞
6.3
6
*
FMC96
NOMESCO Finland
Other operation on aortic valve for insufficiency
+∞
6.3
6
*
I97.0
ICD-10 Finland
Postcardiotomy syndrome
+∞
6.3
6
*
5409
FHL
Other measure in this category
+∞
6.3
6
*
FAE96
NOMESCO Finland
Other connection to pulmonary artery from superior vena cava
+∞
6.3
6
*
FBJ00
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery
+∞
6.3
6
*
3A064, ,
NOMESCO Finland
+∞
6.3
6
*
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
+∞
6.3
6
*
Q22.2
ICD-10 Finland
Congenital pulmonary valve insufficiency
+∞
6.3
6
*
Q22.6
ICD-10 Finland
Hypoplastic right heart syndrome
+∞
6.3
6
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
6.3
6
*
51
HP
Other heart surgery
+∞
6.3
6
*
Q25.3
ICD-10 Finland
Stenosis of aorta
+∞
6.3
6
*
FPF00
NOMESCO Finland
Implantation of epicardial pacemaker with ventricular electrode
+∞
6.3
6
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
+∞
6.3
6
*
XFP02, ,
NOMESCO Finland
+∞
6.3
6
*
3A566, ,
NOMESCO Finland
+∞
6.3
6
*
90492, ,
NOMESCO Finland
+∞
6.3
6
*
74637
ICD-8 Finland
Congenital anomalies of heart, Cor triloculare biatriatum (""""single ventricles"""")
+∞
6.3
6
*
7468X
ICD-9 Finland
Other congenital anomalies of heart, Other specified anomalies of heart[MUU SYDÄMEN EPÄMUODOSTUMA]
+∞
6.3
6
*
7452B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Tetralogy of Fallot[DOUBLE OUTLET RIGHT VENTRICLE AND PULMONAL STENOSIS]
+∞
6.3
6
*
FFE10
NOMESCO Finland
Creation or expansion of ASD in open heart surgery
+∞
6.3
6
*
TFJ02
NOMESCO Finland
Muscle biopsy of heart
27.5
6.3
8
*
324, ,
NOMESCO Finland
27.5
6.3
8
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.3
6.2
16
39
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.7
6.0
34
138
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.1
6.0
26
91
LabWAS
↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
158
52
94.87
263.02
6.9
7.0
154.30
163.15
ng/l
0.05
149
47
67
36
25.85
88.21
4.9
6.0
73.39
101.72
%
3.91
67
36
131
226
12.14
83.76
8.2
3.3
2657.46
192.12
ng/l
2.06
117
116
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
64
39
22.35
79.31
16.8
18.9
0.32
0.29
iu/ml
0.29
41
22
170
454
11.52
72.44
33.4
6.5
1.65
1.08
inr
18.94
149
374
83
111
11.13
63.04
6.0
8.1
180.20
169.59
%
0.49
83
111
117
259
8.16
56.92
4.7
3.3
2.48
2.48
g/l
0.04
117
251
112
240
8.15
56.10
4.5
3.4
20.76
23.86
%
1.73
112
235
139
386
7.57
53.32
4.6
3.5
—
—
—
0
0
151
465
7.54
51.63
15.1
8.6
66.48
89.73
%
21.22
151
458
42
44
11.45
37.09
1.5
1.5
—
—
—
0
0
110
325
5.57
36.90
5.9
4.4
1.83
1.19
mg/l
1.02
86
237
67
131
6.81
35.06
38.3
18.0
-0.13
0.13
mmol/l
0.18
62
115
83
213
5.53
32.25
26.4
14.4
106.48
105.23
mmol/l
1.69
83
213
109
351
5.00
32.22
6.0
3.0
32.32
21.63
ng/l
0.50
70
176
56
99
7.16
32.14
44.6
17.3
1.09
1.12
%
0.15
56
99
157
674
5.19
32.03
5.4
3.6
—
—
estimate
—
0
0
55
97
7.14
31.61
45.3
17.6
0.59
0.68
%
1.31
55
97
121
460
4.44
28.04
4.3
3.7
3.35
2.40
mg/l
1.40
114
414
102
402
3.76
21.27
34.7
18.0
25.16
24.66
mmol/l
0.87
102
402
225
1787
12.91
16.88
50.8
14.9
139.26
139.54
mmol/l
1.16
225
1748
65
217
3.78
16.87
3.0
1.9
—
—
—
0
0
225
1785
12.98
16.87
51.1
14.9
4.03
3.95
mmol/l
4.48
225
1739
64
213
3.78
16.67
3.3
2.0
—
—
—
0
0
90
379
3.26
16.13
10.2
12.2
1.08
1.08
mmol/l
0.01
80
309
70
260
3.43
15.30
3.3
2.1
—
—
—
0
0
38
93
4.70
14.86
8.4
17.4
0.63
0.55
%
0.72
38
93
18
5
38.82
14.67
2.7
14.0
5.02
4.54
kpa
—
18
5
18
5
38.82
14.67
2.7
14.0
5.97
6.02
kpa
—
18
5
29
62
5.21
13.24
8.7
21.6
73.23
69.04
%
0.62
29
62
80
351
2.96
12.92
20.3
10.5
1.80
0.69
mmol/l
3.24
68
263
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
21
16
14.31
12.71
1.6
2.0
139.19
122.38
%
0.35
21
16
80
358
2.89
12.39
20.8
10.6
5.15
5.07
kpa
0.47
80
349
19
12
17.12
12.37
1.6
2.2
166.79
122.75
%
1.59
19
12
73
312
2.96
12.28
20.6
10.9
8.73
9.77
kpa
2.99
73
303
30
80
4.16
10.42
3.8
2.7
71.92
85.70
ml/min/173m2
0.47
12
30
29
83
3.85
9.13
2.7
2.2
—
—
—
0
0
29
85
3.76
8.83
2.7
2.4
—
—
—
0
0
21
48
4.71
8.81
2.2
2.1
—
—
—
0
0
14
10
14.81
8.81
1.1
1.1
82.07
102.70
%
—
14
10
18
38
5.05
8.26
1.4
1.2
1.38
1.50
u/ml
—
8
18
177
1308
2.53
8.25
27.4
9.1
101.50
101.26
ml/min/173m2
0.04
155
1060
23
60
4.15
8.19
1.6
5.6
—
—
—
0
0
18
39
4.92
8.03
1.4
1.3
6.00
2.79
u/ml
0.80
11
19
13
10
13.69
7.98
1.6
1.8
17.31
10.30
umol/l
—
13
10
18
27
7.14
7.76
2.9
2.9
1.17
0.70
index
1.08
18
27
23
63
3.95
7.68
1.9
2.0
—
—
—
0
0
162
1188
2.23
7.12
13.4
10.8
1.70
2.28
e9/l
10.34
151
1016
25
77
3.52
7.06
14.3
12.3
1796.00
416.00
iu/ml
—
5
12
220
1876
4.97
6.96
44.6
17.9
334.59
335.48
g/l
0.67
220
1864
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
13
15
9.11
6.64
2.1
1.1
57.62
117.93
%
2.60
13
15
21
61
3.69
6.46
2.2
2.1
—
—
—
0
0
28
99
3.08
6.36
2.4
1.5
—
—
—
0
0
14
21
7.02
6.14
1.2
1.2
79.43
96.24
%
0.78
14
21
17
34
5.31
6.01
1.3
1.2
—
—
—
0
0
162
1243
2.03
5.58
15.1
13.9
3.71
3.59
e9/l
0.33
152
1028
19
59
3.42
5.30
1.4
5.6
15.11
9.49
%
1.24
19
59
15
31
5.10
5.22
1.3
1.5
—
—
—
0
0
15
40
3.94
5.18
2.7
4.7
11.92
14.31
u/ml
0.07
15
40
219
1928
3.84
5.17
35.0
13.0
24.23
22.22
mg/l
0.47
193
1426
12
19
6.60
5.15
6.2
7.9
115.67
68.11
mg/l
1.22
12
19
28
115
2.63
4.85
2.6
2.0
131.82
106.07
au/ml
0.55
11
52
8
7
11.78
4.82
1.4
1.1
—
—
—
0
0
20
70
3.03
4.62
1.8
1.5
—
—
—
0
0
16
50
3.36
4.42
1.6
1.5
—
—
—
0
0
19
67
3.00
4.34
8.9
13.9
—
2252.09
—
0
11
84
559
1.79
4.16
4.6
4.4
0.52
0.25
e6/l
0.81
60
394
26
113
2.47
4.02
1.5
2.0
—
—
—
0
0
17
60
2.98
3.88
1.4
5.1
236.92
165.23
e6/l
0.47
12
39
26
115
2.42
3.88
2.8
2.0
—
—
—
0
0
62
387
1.82
3.74
3.0
4.1
2.17
1.53
e6/l
0.32
30
209
11
25
4.57
3.67
1.7
1.6
—
—
—
0
0
19
74
2.71
3.65
1.9
1.3
—
—
—
0
0
19
74
2.71
3.65
1.9
1.3
—
—
—
0
0
22
98
2.38
3.24
3.2
2.7
—
—
—
0
0
15
55
2.85
3.22
1.3
5.5
13.87
27.20
%
5.94
15
55
60
390
1.73
3.11
3.2
4.0
0.51
0.61
e6/l
0.17
28
210
22
101
2.30
3.04
2.2
3.9
0.23
0.12
e6/l
0.38
22
96
17
69
2.58
3.04
15.1
5.5
49.57
62.51
%
0.99
17
69
5
5
10.18
2.99
1.4
5.8
2.13
1.40
ratio
—
5
5
12
38
3.27
2.90
1.8
1.6
—
—
—
0
0
17
71
2.51
2.87
2.4
1.4
—
—
—
0
0
22
104
2.23
2.85
1.4
1.4
—
—
—
0
0
8
18
4.56
2.82
2.6
1.6
—
—
—
0
0
5
7
7.27
2.56
1.4
1.9
—
—
—
0
0
6
11
5.57
2.56
10.2
8.5
1.22
1.24
mmol/l
—
6
11
9
26
3.56
2.51
2.0
1.7
—
—
—
0
0
13
51
2.64
2.49
1.4
1.7
—
—
—
0
0
7
17
4.21
2.38
1.0
1.2
364.43
326.18
mg/l
—
7
17
11
39
2.91
2.38
1.9
2.0
—
—
—
0
0
45
293
1.67
2.29
7.1
5.1
377.04
323.68
umol/l
1.64
45
282
6
13
4.71
2.28
2.0
2.0
—
—
—
0
0
0
60
0.00
2.28
0.0
1.2
—
—
—
0
0
167
1850
0.64
2.20
4.0
3.9
—
—
—
0
0
10
231
0.41
2.14
1.0
1.1
—
—
—
0
0
6
15
4.08
2.05
2.0
1.2
—
—
—
0
0
23
127
1.90
2.02
2.3
2.1
264.83
155.25
u/ml
0.92
18
63
60
798
0.66
1.98
1.5
1.9
0.33
2.82
u/ml
—
7
157
12
52
2.38
1.91
2.0
1.8
—
—
—
0
0
0
53
0.00
1.89
0.0
1.2
—
18.05
—
0
11
9
35
2.63
1.82
2.0
3.4
139.44
130.73
g/l
—
9
30
9
35
2.63
1.82
1.4
1.7
—
—
—
0
0
17
90
1.96
1.70
9.1
4.0
—
—
—
0
0
12
56
2.21
1.64
2.4
1.9
1.14
4.56
iu/l
—
6
24
5
14
3.63
1.62
1.6
2.0
—
—
—
0
0
5
14
3.63
1.62
1.6
2.0
—
—
—
0
0
5
14
3.63
1.62
1.6
2.0
—
—
—
0
0
8
33
2.47
1.55
2.0
2.0
—
—
—
0
0
14
72
2.01
1.52
1.4
1.2
—
—
—
0
0
0
45
0.00
1.51
0.0
1.2
—
—
—
0
0
12
60
2.06
1.41
1.1
3.4
—
—
—
0
0
5
17
2.98
1.36
2.4
1.3
—
—
—
0
0
30
204
1.54
1.31
3.1
2.8
36.04
31.92
u/l
0.26
25
169
10
48
2.13
1.29
1.0
1.0
156.20
164.19
g/l
—
10
48
5
18
2.82
1.29
1.6
1.5
—
—
—
0
0
6
26
2.34
1.19
5.0
6.5
—
—
—
0
0
0
36
0.00
1.15
0.0
1.2
—
—
—
0
0
7
135
0.50
1.02
1.1
1.9
—
—
—
0
0
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
0
30
0.00
0.98
0.0
1.4
—
0.37
—
0
30
0
30
0.00
0.98
0.0
1.2
—
—
—
0
0
0
31
0.00
0.97
0.0
1.2
—
—
—
0
0
7
128
0.53
0.91
1.4
1.4
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
0
27
0.00
0.78
0.0
1.3
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
0
27
0.00
0.78
0.0
1.6
—
—
—
0
0
0
27
0.00
0.78
0.0
1.0
—
—
—
0
0
0
28
0.00
0.76
0.0
1.3
—
—
—
0
0
21
282
0.72
0.70
1.2
1.3
9.41
18.52
iu/ml
—
7
65
5
27
1.87
0.69
1.8
2.4
0.00
0.00
g/l
—
5
27
12
78
1.57
0.67
5.0
4.1
1.26
1.23
mmol/l
0.88
12
64
5
28
1.80
0.66
1.8
2.4
0.00
0.00
g/l
—
5
28
17
234
0.70
0.66
1.8
2.3
12.45
13.01
nmol/l
0.10
17
221
40
482
0.79
0.63
1.9
2.3
—
—
—
0
0
130
1396
0.84
0.61
3.9
3.1
5.48
5.56
mmol/l
0.49
124
1303
33
265
1.29
0.61
3.2
2.9
354.58
343.92
nmol/l
0.10
33
252
0
20
0.00
0.60
0.0
3.8
—
751.20
—
0
20
0
21
0.00
0.60
0.0
1.8
—
12.60
—
0
5
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
48
407
1.23
0.57
3.9
3.7
0.12
0.00
estimate
0.48
17
142
20
254
0.77
0.49
1.9
2.0
—
—
—
0
0
13
94
1.41
0.47
1.2
1.1
0.84
0.90
g/l
0.41
13
94
16
208
0.75
0.46
1.8
2.8
0.50
1.13
ug/l
6.02
11
193
27
221
1.25
0.45
1.3
1.5
—
—
—
0
0
45
513
0.85
0.42
2.0
2.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
2.4
—
73.98
—
0
10
0
16
0.00
0.41
0.0
7.9
—
—
—
0
0
0
16
0.00
0.41
0.0
7.9
—
45830.83
—
0
6
0
17
0.00
0.41
0.0
1.1
—
223.70
—
0
17
0
17
0.00
0.41
0.0
1.1
—
2.33
—
0
11
0
17
0.00
0.41
0.0
1.1
—
0.71
—
0
10
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
144
1373
1.13
0.37
4.7
3.3
1.23
1.24
mmol/l
0.07
138
1307
14
108
1.32
0.36
2.2
1.7
—
—
—
0
0
5
79
0.62
0.36
2.8
2.5
1.36
0.51
nmol/l
—
5
70
11
145
0.75
0.36
1.0
1.2
—
5.24
—
0
10
6
42
1.44
0.36
2.3
2.4
—
—
—
0
0
6
44
1.37
0.34
1.3
1.3
—
—
—
0
0
6
86
0.69
0.33
1.0
1.7
—
—
—
0
0
154
1481
1.12
0.32
4.8
3.8
2.48
2.76
mmol/l
3.68
149
1419
14
174
0.79
0.31
1.5
1.3
64.61
160.42
u/ml
—
7
55
12
93
1.31
0.30
1.0
1.0
1.38
1.49
g/l
0.58
12
93
11
141
0.77
0.30
1.1
1.2
—
—
—
0
0
25
286
0.86
0.25
1.8
2.2
—
—
—
0
0
56
604
0.90
0.24
4.3
3.1
0.00
0.00
estimate
-0.00
15
130
5
40
1.26
0.22
2.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
26.89
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
4.18
—
0
5
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
2.03
—
0
8
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
163
1669
0.92
0.20
5.3
4.5
2.18
1.88
mu/l
2.07
157
1586
94
898
1.08
0.19
4.4
3.7
149.60
0.00
estimate
0.78
20
146
42
453
0.91
0.18
3.6
2.9
0.00
0.00
estimate
-0.00
15
126
12
142
0.84
0.18
1.2
1.2
—
—
—
0
0
5
69
0.72
0.17
1.0
1.7
—
—
—
0
0
93
894
1.07
0.16
4.4
3.7
0.00
0.00
estimate
-0.00
18
150
47
497
0.93
0.13
1.9
1.7
87.95
96.49
pmol/l
0.61
26
264
27
292
0.91
0.12
4.6
5.0
18.22
12.65
mg/mmol
0.23
20
214
15
168
0.89
0.12
1.4
2.4
11.67
5.70
u/l
—
10
109
15
167
0.89
0.11
1.3
1.6
1073.91
888.84
mu/l
—
10
147
143
1456
0.95
0.10
4.6
4.0
15.72
14.44
pmol/l
6.26
137
1367
93
904
1.05
0.10
4.5
3.7
0.00
0.00
estimate
-0.00
15
140
40
418
0.95
0.08
4.1
3.1
1.02
1.02
kg/l
0.16
23
266
12
132
0.90
0.07
1.7
1.7
—
—
—
0
0
84
848
0.99
0.01
1.9
2.0
—
—
—
0
0
10
98
1.02
0.00
1.0
1.0
21.60
19.16
mmol/l
—
10
98
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
21.67
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.9
—
—
—
0
0
8
80
1.00
-0.00
1.0
1.2
—
2.57
—
0
8
0
9
0.00
-0.00
0.0
1.1
—
62.78
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
65.83
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
71
0.99
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
4.57
—
0
5
7
69
1.01
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.0
—
2.17
—
0
6
0
9
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
14.42
—
0
5
0
5
0.00
-0.00
0.0
7.8
—
18.34
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
11.40
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
67.57
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO | 9.355 [4.38, 19.97] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.586 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 576 females with Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO | 7.222 [4.72, 11.04] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 760 males with Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.913% | 1.304% |
| 5 | 6.522% | 6.938% |
| 10 | 15.52% | 17.531% |
| 15 | 25.751% | 31.095% |
| 20 | 40.699% | 46.393% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_CARDIAC_CHAMB_CONNECTIO – Congenital malformations of cardiac chambers and connections
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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