Tooth eruption problems

K11_ERUPTION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

3 out of 7 registries used, show all original rules.

6825

4. Check minimum number of events

None

6825

5. Include endpoints

None

6825

6. Filter based on genotype QC (FinnGen only)

6825

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF10

Similar endpoints

List of similar endpoints to Tooth eruption problems based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

None

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 91279 51833 39146
Only index persons 83055 47728 35327
Unadjusted period prevalence (%)
Whole population 1.31 1.48 1.09
Only index persons 1.58 1.75 1.35
Median age at first event (years)
Whole population 18.48 19.71 16.75
Only index persons 19.80 20.92 18.28

-FinnGen-

Key figures

All Female Male
Number of individuals 6825 4897 1928
Unadjusted period prevalence (%) 1.44 1.67 0.85
Median age at first event (years) 26.37 25.69 28.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5644
Matched controls
56052
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.2
323.0
3519
19034
K00.68
ICD-10 Finland
Other disturbance in the tooth eruption
+∞
323.0
1747
*
K00.69
ICD-10 Finland
Disorders in the tooth eruption UNS
+∞
323.0
528
*
K01.0
ICD-10 Finland
Embedded teeth
+∞
323.0
3532
*
EBA10
NOMESCO Finland
Surgical removal of tooth
6.7
323.0
2882
7537
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
6.0
258.8
774
1435
EBA00
NOMESCO Finland
Extraction of tooth
2.6
243.3
2809
15474
K05.32
ICD-10 Finland
Periodontitis NOS
2.9
191.7
1416
5789
WX110
NOMESCO Finland
Local anesthesy
2.5
174.9
4503
34478
SAA01
NOMESCO Finland
Simple examination of mouth
2.5
168.1
4670
36687
WZA90
NOMESCO Finland
Other doctors statement
2.3
162.5
1949
10296
SAA03
NOMESCO Finland
Extended examination of mouth
2.1
154.8
3124
20741
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.1
142.1
2174
12657
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
3.9
140.5
645
1814
WX290
NOMESCO Finland
Other blockade of nerve
2.0
135.5
3433
24392
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.1
135.2
2251
13510
SAA02
NOMESCO Finland
Basic examination of mouth
2.1
114.7
4570
37383
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
4.3
110.7
446
1105
ECA00
NOMESCO Finland
Surgical exposure of tooth
12.2
95.0
177
148
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.3
64.3
652
2996
KMAK
NOMESCO Finland
NA
1.6
61.7
2958
22887
Z01.2
ICD-10 Finland
Dental examination
1.6
60.5
2734
20795
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
60.3
2814
21569
EFA50
NOMESCO Finland
Excision of cyst of jaws
9.9
55.3
114
117
K09.03
ICD-10 Finland
Cyst eruption
16.2
53.2
87
54
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
53.2
2894
22728
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
4.9
52.5
179
373
EMAK
NOMESCO Finland
NA
3.0
51.4
313
1070
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.3
51.3
527
2424
K00.7
ICD-10 Finland
Teething syndrome
2.2
48.4
510
2373
K02.1
ICD-10 Finland
Caries of dentine
1.5
47.3
3575
29861
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
45.8
1907
13904
WZA00
NOMESCO Finland
Short statement of of health and health related matters
2.3
43.5
445
2037
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
6.7
42.1
110
166
K05.22
ICD-10 Finland
Acute pericoronitis
1.9
41.2
709
4008
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
4.7
40.9
144
311
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.5
40.5
3511
29642
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
40.5
4057
35311
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.3
38.8
396
1808
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
2.3
38.6
368
1624
127
Kela drug reimbursment
Transplant complication
5.2
38.3
123
241
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.5
37.3
1841
13782
SBB10
NOMESCO Finland
Teeth copy
1.8
37.2
745
4420
K07.13
ICD-10 Finland
Retrognaty, mandibular
3.4
36.3
185
557
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.1
35.9
456
2292
K01.1
ICD-10 Finland
Impacted teeth
3.8
33.0
144
383
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.9
32.8
520
2843
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
2.0
32.5
428
2182
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
1.9
32.3
542
3023
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.4
32.3
282
1190
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
3.9
32.0
135
348
-1
NOMESCO Finland
NA
1.4
31.3
2387
19250
D82
ICPC
Teeth/gum disease
1.4
30.7
2165
17193
Z94.0
ICD-10 Finland
Kidney transplant status
5.4
30.6
93
172
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
30.5
3125
26481
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
2.0
30.4
416
2149
SXA20
NOMESCO Finland
Local application of medicine to mouth
1.9
29.7
466
2536
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.7
28.8
703
4399
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.5
28.6
1142
8080
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
2.0
27.7
360
1823
K10.3
ICD-10 Finland
Alveolitis of jaws
2.1
27.6
313
1497
K01.12
ICD-10 Finland
Retained canine with obstruction in the upper jaw
6.3
26.9
72
114
L04AA06
ATC
mycophenolic acid; systemic
4.0
26.8
109
273
D19
ICPC
Teeth/gum symptom/complaint
1.4
26.7
1521
11537
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
2.1
26.6
322
1586
SDA02
NOMESCO Finland
Parodonthologic therapy
1.4
26.1
1763
13779
L04AA01
ATC
[U] ciclosporin; systemic
5.1
26.0
83
163
SXC05
NOMESCO Finland
Other oral or dental procedure
1.7
25.7
531
3162
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.5
24.9
1013
7170
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
2.1
24.4
292
1430
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.4
24.2
1741
13717
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
24.2
3029
26042
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
24.0
1639
12796
SXC03
NOMESCO Finland
Other oral or dental procedure
4.9
23.9
79
162
K00.00
ICD-10 Finland
Hypodontia
2.8
23.7
158
575
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
23.5
1101
8009
K05.30
ICD-10 Finland
Periodontitis complex
1.9
23.0
352
1897
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.5
22.6
789
5386
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.7
22.3
451
2665
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
1.9
22.2
349
1896
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
4.6
21.5
75
163
SJC00
NOMESCO Finland
Bracket with fixed attachment
6.2
21.5
58
94
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.8
21.3
91
240
K07.60
ICD-10 Finland
Snapping jaw
1.9
21.1
325
1754
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
6.1
20.8
57
94
EEC05
NOMESCO Finland
Le Fort I osteotomy
5.9
20.6
58
99
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.4
20.3
1241
9452
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
1.8
20.2
357
2020
VALMI
NOMESCO Finland
NA
1.3
19.9
1711
13769
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
19.8
4668
43406
ECB00
NOMESCO Finland
Suture of gingiva
2.4
19.7
172
729
EBB10
NOMESCO Finland
Insertion of dental implant
3.8
19.5
83
219
A11CC03
ATC
alfacalcidol; systemic
3.5
19.5
93
270
EB1MA
NOMESCO Finland
Cephalometry with X-ray
1.8
19.3
321
1781
K01.16
ICD-10 Finland
Retained molar with obstruction in the upper jaw
2.4
19.2
168
713
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.3
19.0
58
110
J01FF01
ATC
clindamycin; systemic
1.4
18.8
991
7340
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.3
18.7
2240
18863
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
1.8
18.7
341
1951
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
18.6
817
5845
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.7
18.4
82
225
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
1.6
18.4
542
3546
K00.6
ICD-10 Finland
Disturbances in tooth eruption
3.9
18.4
75
191
137
Kela drug reimbursment
Uraemia requiring dialysis
5.1
17.5
55
108
EB1WA
NOMESCO Finland
NA
5.2
17.2
53
102
R4110
NOMESCO Finland
Physiotherapy
1.4
17.2
897
6620
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
1.7
17.0
359
2147
A12AA04
ATC
calcium carbonate; oral
4.1
16.8
66
163
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
3.8
16.7
70
183
K02.0
ICD-10 Finland
Caries limited to enamel
1.4
16.7
1125
8672
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.4
16.5
828
6062
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
2.0
16.2
217
1115
N02BE01
ATC
paracetamol; systemic, rectal
1.3
16.1
3836
34967
J01DB01
ATC
cefalexin; oral
1.3
16.0
4181
38551
K07.24
ICD-10 Finland
Open bite
2.4
16.0
133
552
K01.19
ICD-10 Finland
Retained tooth with obstruction barrier UNS
7.4
15.8
37
50
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
2.0
15.7
211
1082
K01.10
ICD-10 Finland
Retained front tooth with obstruction in the upper jaw
12.1
15.7
28
23
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
5.6
15.7
45
80
WX002
NOMESCO Finland
Sedation and analgesia
1.5
15.6
570
3911
ZXA10
NOMESCO Finland
Bilateral
1.5
15.6
623
4361
K07.23
ICD-10 Finland
Deep bite
1.8
15.2
269
1527
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
1.8
15.1
251
1393
ZXA00
NOMESCO Finland
Right side
1.4
15.1
688
4944
K03.66
ICD-10 Finland
Tooth plaque
1.6
15.0
378
2374
Z49.2
ICD-10 Finland
Other dialysis
5.4
14.6
43
79
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
4.4
14.6
52
118
Z54.0
ICD-10 Finland
Convalescence following surgery
2.7
14.3
97
359
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
14.2
267
1542
L04AD01
ATC
ciclosporin; systemic
2.6
13.7
99
383
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.0
13.7
179
914
ZXA05
NOMESCO Finland
Left side
1.4
13.4
618
4442
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.7
13.4
93
351
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
13.4
184
956
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.5
13.3
549
3867
A02BC05
ATC
esomeprazole; systemic
1.3
13.3
1213
9742
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
5.7
13.2
37
65
B05DA
ATC
Isotonic solutions
4.8
13.1
43
90
K01.14
ICD-10 Finland
Retained premolar with obstruction in the upper jaw
10.9
12.9
24
22
P01AB01
ATC
metronidazole; oral, rectal
1.3
12.9
1496
12386
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
6.1
12.7
34
56
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
12.7
1495
12394
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
12.6
1617
13552
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
12.6
497
3470
K01
ICD-10 Finland
Embedded and impacted teeth
2.5
12.5
100
409
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
12.4
738
5551
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
12.4
680
5044
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
12.3
190
1031
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
1.9
12.3
184
988
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
1.6
12.3
296
1838
K06.18
ICD-10 Finland
Another gingival hyperplasia
5.2
12.3
37
71
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
2.1
12.3
134
636
N02AX02
ATC
tramadol; systemic, rectal
1.3
12.2
1177
9507
K03.30
ICD-10 Finland
Internal granuloma of pulp
5.9
12.1
33
56
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
1.8
12.0
203
1137
Z49.0
ICD-10 Finland
Preparatory care for dialysis
5.1
12.0
37
73
K07.10
ICD-10 Finland
Asymmetry of jaw
3.9
11.9
47
119
K09.09
ICD-10 Finland
Odontogenic developmental cyst UNS
13.3
11.9
20
15
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
1.6
11.8
280
1730
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.6
11.7
51
141
Z94.4
ICD-10 Finland
Liver transplant status
5.8
11.7
32
55
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
5.4
11.4
33
61
K05.31
ICD-10 Finland
Periodontitis pronounced
1.8
11.3
198
1125
EBA00
SPAT
NA
2.2
11.2
112
512
K07.38
ICD-10 Finland
Other anomaly in the position of the teeth
1.9
11.2
163
868
TJW99
NOMESCO Finland
Other minor procedure in gastrointestinal endoscopy
9.5
11.2
22
23
F45.8
ICD-10 Finland
Other somatoform disorders
1.5
10.9
436
3049
B05DB
ATC
Hypertonic solutions
4.8
10.9
35
73
WX704
NOMESCO Finland
Intubation
1.6
10.7
256
1588
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
10.5
10.7
20
19
L03
ICPC
Low back symptom/complaint
1.3
10.5
1070
8683
B03XA01
ATC
erythropoietin; parenteral
4.4
10.4
36
81
EBA10
SPAT
NA
2.9
10.4
61
210
TK800
NOMESCO Finland
Hemodialysis
2.8
10.4
66
239
K08.3
ICD-10 Finland
Retained dental root
1.8
10.4
177
996
EBB15
NOMESCO Finland
Insertion of dental implant abutment
3.7
10.3
44
120
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
4.3
10.2
36
83
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
5.2
10.2
30
57
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.6
10.1
283
1828
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
10.1
1394
11729
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.1
9.9
107
509
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.1
9.8
102
478
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.0
9.7
120
602
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
9.7
1743
15062
5AB14
NOMESCO Finland
NA
6.9
9.7
23
33
K12.2
ICD-10 Finland
Cellulitis and abscess of mouth
2.8
9.7
58
204
K08.80
ICD-10 Finland
Toothache NOS
1.5
9.5
379
2650
N18.0
ICD-10 Finland
End-stage renal disease
3.8
9.5
38
99
H02AB04
ATC
methylprednisolone; systemic
1.4
9.5
383
2683
KAY20
NOMESCO Finland
NA
1.5
9.5
274
1787
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
9.4
2883
26178
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
7.5
9.3
21
28
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
9.3
640
4917
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.8
9.3
56
198
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
8.9
242
1555
K05.39
ICD-10 Finland
Periodontitis UNS
2.9
8.9
52
180
R50.9
ICD-10 Finland
Fever, unspecified
1.3
8.9
630
4859
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
7.4
8.9
20
27
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
8.8
490
3638
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
3.3
8.8
43
132
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
4.3
8.8
31
72
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
1.5
8.8
329
2270
B03XA02
ATC
darbepoetin alfa; parenteral
3.0
8.8
48
160
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.4
8.8
468
3452
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
8.7
1739
15145
TK820
NOMESCO Finland
Peritoneal dialysis
4.9
8.7
27
55
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.2
8.7
1050
8676
EB1KA
NOMESCO Finland
Partial (restricted area) panoramic tomography of teeth or jaw
3.2
8.7
44
139
G50.1
ICD-10 Finland
Atypical facial pain
2.6
8.4
61
239
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
8.4
1169
9817
Z94.1
ICD-10 Finland
Heart transplant status
5.9
8.4
22
37
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
1.4
8.4
342
2405
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
4.2
8.3
30
72
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.3
8.3
519
3929
H02AB09
ATC
hydrocortisone; systemic
1.9
8.3
115
607
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
8.3
182
1110
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.3
8.2
830
6714
K03.00
ICD-10 Finland
Approximal wear
1.6
8.2
203
1277
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
5.5
8.2
23
42
K05.18
ICD-10 Finland
Chronic gingivitis
1.5
8.2
244
1605
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
4.7
8.2
26
55
A02BC03
ATC
lansoprazole; oral
1.3
8.1
665
5234
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
2.6
8.1
57
223
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
1.5
8.0
278
1892
K07.14
ICD-10 Finland
Retrognaty, maxillary
2.7
8.0
51
186
N03AX12
ATC
gabapentin; oral
1.4
8.0
401
2928
ECB15
NOMESCO Finland
Plastic repair of oronasal or oroantral fistula
4.4
8.0
27
61
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
4.0
8.0
30
75
C03CA01
ATC
furosemide; systemic
1.4
7.9
342
2430
UJF32
NOMESCO Finland
Coloscopy
1.3
7.8
591
4601
A41.9
ICD-10 Finland
Sepsis, unspecified
2.0
7.8
92
455
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
1.7
7.8
159
952
SMAK
NOMESCO Finland
NA
2.8
7.8
46
162
K00.29
ICD-10 Finland
Other or indefinite deviation in the shape or size of the teeth
8.4
7.8
16
19
J01CA04
ATC
amoxicillin; systemic
1.2
7.7
4696
44910
L17
ICPC
Foot/toe symptom/complaint
1.2
7.7
1003
8354
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.2
7.7
72
324
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
1.6
7.6
171
1050
J02AC01
ATC
fluconazole; systemic
1.2
7.6
1635
14296
G40.9
ICD-10 Finland
Epilepsy, unspecified
1.8
7.6
123
684
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
2.7
7.6
49
182
D54
ICPC
Digestive, Repair/fix-suture/cast/prosth device
24.9
7.5
10
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
7.5
593
4643
H29
ICPC
Ear symptom/complaint other
1.4
7.5
340
2442
ZX120
NOMESCO Finland
Intravenous
1.5
7.5
277
1912
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
2.0
7.5
94
480
K05.3
ICD-10 Finland
Chronic periodontitis
1.9
7.5
104
549
R11
ICD-10 Finland
Nausea and vomiting
1.4
7.4
361
2623
C02CA01
ATC
prazosin; oral
4.4
7.4
25
57
602
Kela drug reimbursment
Children's severe malnutrition
2.4
7.3
56
230
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.5
7.3
32
92
N18.8
ICD-10 Finland
Other chronic renal failure
2.4
7.3
59
250
H02AB06
ATC
prednisolone; systemic
1.2
7.3
1586
13885
D01
ICPC
Abdominal pain/cramps general
1.3
7.2
664
5309
K09.00
ICD-10 Finland
Cyst dentigerous
15.6
7.2
11
7
K09.08
ICD-10 Finland
Another edontogenic developmental cyst
15.6
7.2
11
7
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
7.2
76
362
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
7.2
311
2215
R03AC02
ATC
salbutamol; inhalant
1.2
7.2
2397
21728
KAY40
NOMESCO Finland
NA
1.4
7.1
313
2231
WX720
NOMESCO Finland
Own respiration
1.8
7.1
115
640
101
Kela drug reimbursment
Anterior pituitary hypofunction
2.6
7.1
47
179
R51.80
ICD-10 Finland
Headache
1.2
7.1
779
6365
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.0
7.0
84
420
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
7.0
552
4323
K03.80
ICD-10 Finland
Irradiated enamel
1.5
7.0
199
1295
XF602
NOMESCO Finland
Bloodpressure monitoring
2.7
7.0
45
165
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
5.6
7.0
19
34
EDC30
NOMESCO Finland
Genioplasty
9.9
7.0
13
13
K10.21
ICD-10 Finland
Osteoradionecrosis of jaw (acute)(chronic)(suppurative)
9.9
7.0
13
13
K07.4
ICD-10 Finland
Malocclusion, unspecified
1.9
6.9
94
494
SJA01
NOMESCO Finland
Estimation of need for orthodontic care
3.3
6.9
32
96
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
2.9
6.9
40
139
C08CA02
ATC
felodipine; oral
1.8
6.9
109
603
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.3
6.9
58
249
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
10.9
6.8
12
11
WX110
SPAT
NA
1.5
6.7
214
1433
EBA12
SPAT
NA
5.0
6.7
20
40
KAY60
NOMESCO Finland
NA
1.6
6.7
153
944
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
4.5
6.7
22
49
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.7
1079
9173
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.5
6.6
204
1356
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
3.4
6.6
30
89
ECB20
NOMESCO Finland
Oral alveoplasty
3.4
6.6
29
84
S18
ICPC
Laceration/cut
1.2
6.6
1391
12125
EWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of teeth, jaws, mouth and pharynx
7.7
6.6
14
18
K13.78
ICD-10 Finland
Other change in the oral mucosa
2.3
6.5
58
256
M48.0
ICD-10 Finland
Spinal stenosis
1.7
6.4
132
792
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
6.4
732
5996
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
5.3
6.4
18
34
R74
ICPC
Upper respiratory infection acute
1.2
6.4
1947
17476
K03.5
ICD-10 Finland
Ankylosis of teeth
7.3
6.4
14
19
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
1.9
6.4
87
459
Z29.8
ICD-10 Finland
Other specified prophylactic measures
1.7
6.4
133
805
L01
ICPC
Neck symptom/complaint
1.3
6.3
577
4605
EB1HA
SPAT
NA
2.5
6.3
46
186
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
6.3
1179
10161
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
3.3
6.3
29
88
196
Kela drug reimbursment
Paricalcitol and cinacalcet
4.5
6.2
20
44
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.3
6.2
379
2860
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
3.2
6.2
29
89
S29
ICPC
Skin symptom/complaint other
1.3
6.2
640
5191
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.8
6.2
105
599
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
1.8
6.1
103
586
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
3.5
6.1
26
74
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.6
6.1
163
1052
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.2
6.1
740
6109
WX1PA
NOMESCO Finland
Total body mineral density measurement with Dual energy X-ray absorptiometry (DXA)
4.4
6.1
20
45
A02BC02
ATC
pantoprazole; systemic
1.2
6.1
2072
18736
A28
ICPC
Limited function/disability NOS
1.5
6.1
215
1475
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.3
6.1
50
214
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.9
6.1
79
412

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
97
261
3.72
30.80
38.6
39.3
7.1
7.2
ug/l
0.13
88
240
90
251
3.58
27.15
33.2
27.4
113.8
130.5
ug/l
0.95
78
212
2099
17169
1.30
21.03
7.8
6.1
—
—
—
0
0
203
1005
2.03
19.49
4.5
5.7
1.3
1.2
mmol/l
0.39
178
886
3025
26173
1.26
18.60
7.1
5.7
55.1
55.4
%
0.83
2869
24735
3057
26539
1.25
18.05
7.4
5.9
31.0
30.7
%
0.64
2895
25009
2888
24939
1.25
17.77
7.5
6.0
2.7
2.8
%
1.76
2734
23369
2901
25122
1.25
17.22
7.8
6.2
8.0
8.0
%
0.33
2758
23703
2782
24000
1.25
17.02
7.6
6.1
0.6
0.6
%
0.28
2627
22510
4018
36234
1.24
15.86
4.2
3.5
8.5
8.4
mm/h
0.31
3802
33750
3153
27717
1.23
15.81
7.3
5.9
2.0
2.0
e9/l
0.16
2861
24890
1969
16431
1.26
15.80
6.4
4.7
37.2
37.3
g/l
0.34
1863
15280
3016
26402
1.23
15.68
7.5
6.0
0.0
0.0
e9/l
0.01
2683
23164
3007
26326
1.23
15.58
7.5
6.0
0.5
0.5
e9/l
0.62
2675
23140
3111
27339
1.23
15.54
7.9
6.3
0.2
0.2
e9/l
1.66
2807
24399
2217
18865
1.24
14.74
9.4
5.9
1.2
1.2
mmol/l
0.20
1922
16102
261
1532
1.71
14.73
9.8
10.9
—
—
—
0
0
3382
30114
1.22
14.44
9.8
8.1
3.9
4.0
e9/l
1.51
3014
26410
1500
12288
1.27
13.74
3.8
3.1
1.0
1.0
kg/l
2.05
210
1815
296
1831
1.63
13.69
3.6
3.0
124.0
125.4
ng/l
0.03
264
1575
4081
37241
1.21
12.83
4.5
3.8
—
—
—
0
0
1941
16517
1.23
12.42
4.1
3.0
30.4
29.3
u/l
0.52
1869
15725
1153
9268
1.28
12.17
4.8
3.7
—
—
—
0
0
54
183
2.94
12.08
5.1
4.4
—
—
—
0
0
2417
21128
1.21
11.58
6.3
5.0
10.0
10.3
umol/l
0.88
2254
19645
122
612
1.99
11.46
5.4
7.8
11.1
11.6
mmol/l
0.63
106
551
1545
12925
1.24
11.46
3.2
2.7
2.3
2.4
mmol/l
0.51
1399
11631
122
613
1.99
11.41
5.4
7.8
105.0
105.7
mmol/l
0.81
106
552
1613
13564
1.23
11.39
2.7
2.5
57.4
55.2
u/l
0.46
1500
12523
1299
10671
1.25
11.35
5.2
3.5
7.4
7.4
ph
0.46
218
2048
683
5163
1.34
11.27
3.2
2.4
23.3
24.0
%
0.65
584
4505
823
6399
1.31
11.16
3.0
2.3
14.4
14.7
umol/l
0.49
775
5953
746
5725
1.33
11.10
3.0
2.3
2.5
2.5
g/l
0.52
706
5305
352
2382
1.49
10.96
7.8
4.4
81.8
71.4
ng/l
1.41
338
2189
3727
33975
1.19
10.95
7.6
6.1
77.0
74.9
u/l
1.37
3538
31898
34
92
3.67
10.91
8.0
7.5
2.4
2.6
mg/l
0.18
27
79
441
3120
1.43
10.89
9.0
8.0
0.8
0.6
mmol/l
0.36
327
2310
2411
21160
1.20
10.87
3.4
2.9
—
5.9
—
0
9
180
1047
1.72
10.60
4.5
5.8
0.9
0.9
%
0.11
165
976
758
5880
1.31
10.43
1.8
1.6
—
—
—
0
0
43
141
3.03
10.24
3.5
2.6
—
—
—
0
0
1967
17028
1.20
10.14
9.2
5.5
1.2
1.2
mmol/l
0.09
1817
15586
663
5089
1.32
9.83
12.4
6.4
1.1
1.1
mmol/l
1.47
634
4789
1470
12425
1.22
9.64
7.6
6.5
—
—
—
0
0
731
5718
1.30
9.43
3.5
2.7
29.6
29.5
s
0.28
706
5522
3908
36042
1.17
9.15
4.5
3.9
2082.6
1453.9
e6/l
0.14
51
431
782
6194
1.28
9.14
3.3
2.8
609.5
480.4
ng/l
0.30
413
3108
534
4015
1.34
9.12
3.0
2.6
10.0
10.5
g/l
2.43
505
3706
493
3663
1.36
9.11
4.4
3.5
1.6
1.6
%
0.66
449
3299
428
3115
1.38
9.00
9.0
8.0
5.0
5.0
kpa
0.09
404
2985
427
3114
1.38
8.87
8.9
8.0
13.9
14.0
kpa
0.16
404
2985
62
265
2.33
8.83
3.1
3.1
52.2
42.8
mg/l
0.12
46
202
382
2744
1.40
8.69
9.7
8.5
96.4
96.5
%
0.09
357
2647
425
3114
1.37
8.58
15.5
8.4
7.6
6.7
mmol/l
2.41
417
2993
1729
14988
1.19
8.50
1.7
1.6
99.1
97.7
pmol/l
0.61
922
8447
2982
27022
1.16
8.49
3.7
3.1
0.0
0.0
estimate
1.47
568
5536
247
1643
1.51
8.44
7.1
7.0
24.3
23.9
mmol/l
0.70
222
1537
724
5746
1.28
8.32
7.4
4.3
0.8
0.8
mmol/l
5.65
684
5411
172
1064
1.62
8.11
4.1
5.7
1.8
1.7
%
0.13
157
990
356
2561
1.40
8.05
9.5
8.7
120.3
123.7
g/l
2.42
333
2478
53
221
2.38
8.01
2.2
1.7
—
—
—
0
0
238
1591
1.50
7.96
15.0
7.8
1.3
1.2
mg/l
2.74
231
1517
98
528
1.85
7.59
2.3
1.6
—
—
—
0
0
98
528
1.85
7.59
2.3
1.6
—
—
—
0
0
346
2503
1.39
7.58
3.3
3.1
65.9
71.0
e9/l
1.97
251
1782
98
529
1.85
7.55
2.3
1.6
—
—
—
0
0
98
529
1.85
7.55
2.3
1.6
—
—
—
0
0
711
5698
1.26
7.53
2.2
1.9
—
—
—
0
0
5200
49368
1.18
7.51
15.1
11.6
13.2
13.3
%
0.76
5101
48354
1675
14613
1.18
7.49
2.6
2.3
—
—
—
0
0
2248
20073
1.16
7.49
2.8
2.3
71.0
70.0
nmol/l
1.06
2122
18810
498
3819
1.31
7.44
9.4
4.8
5.9
5.9
kpa
0.15
480
3690
1121
9452
1.21
7.35
2.7
2.8
101.4
110.5
ug/g
0.50
894
7391
461
3505
1.32
7.33
12.7
8.4
—
—
—
0
0
2924
26656
1.15
7.26
5.7
4.2
6.2
6.2
mmol/l
0.34
2576
23508
358
2626
1.37
7.22
10.7
5.1
24.1
24.0
mmol/l
0.46
335
2451
306
2194
1.40
7.09
1.1
1.1
4.3
4.3
u/ml
0.01
43
318
492
3793
1.31
7.08
9.5
4.8
1.7
1.6
mmol/l
0.25
384
3044
2977
27213
1.15
7.03
3.7
3.1
0.0
0.0
estimate
0.25
576
5625
3046
27903
1.15
6.95
2.9
2.6
—
—
—
0
0
1423
12337
1.18
6.78
2.4
2.2
2.5
2.6
mg/l
2.20
1262
10589
3278
30211
1.14
6.77
3.2
2.9
72.3
67.4
ug/l
0.93
3144
28568
2955
27046
1.14
6.76
5.0
4.2
0.0
0.0
estimate
1.60
590
5777
1412
12238
1.18
6.75
3.6
3.1
—
—
—
0
0
4647
43870
1.15
6.70
4.0
3.9
14.4
14.4
pmol/l
0.02
4297
40153
405
3069
1.33
6.61
2.0
1.7
1.2
1.3
g/l
0.72
386
2862
235
1630
1.44
6.58
5.4
5.1
—
—
—
0
0
276
1972
1.40
6.55
3.8
2.5
0.2
0.2
e6/l
1.40
264
1898
1940
17277
1.16
6.50
1.4
1.4
1.4
1.7
u/ml
0.62
481
4611
1495
13055
1.17
6.49
6.7
5.1
1.1
1.1
inr
0.37
537
4698
162
1047
1.54
6.42
1.5
1.4
—
—
—
0
0
1039
8807
1.20
6.39
3.2
2.5
516.8
565.6
mosm/kgh2o
0.60
898
7511
5265
50231
1.16
6.33
12.6
9.2
3.9
3.9
mmol/l
2.66
5087
48406
982
8296
1.20
6.25
1.5
1.4
20.1
19.8
nmol/l
0.25
869
7436
5251
50126
1.16
6.10
12.5
9.2
139.4
139.5
mmol/l
3.00
5088
48454
1102
9455
1.18
5.88
3.1
2.4
7.3
8.4
e6/l
1.52
964
8222
195
1336
1.46
5.87
2.1
1.7
4.3
4.5
titre
—
6
24
5410
51801
1.16
5.87
15.1
11.6
334.0
333.8
g/l
0.53
5373
51332
611
4953
1.24
5.86
4.8
3.0
5.9
6.4
umol/l
0.57
519
4157
1651
14631
1.15
5.82
1.5
1.4
2.0
2.0
g/l
1.06
1047
9095
1242
10776
1.17
5.78
2.3
2.0
1.2
1.0
mg/l
0.83
874
7553
5736
55199
1.18
5.74
12.4
9.5
19.7
20.3
mg/l
0.68
4443
41288
120
744
1.61
5.73
1.7
1.6
—
—
—
0
0
5235
50029
1.15
5.72
4.7
4.4
1.9
1.9
mu/l
0.06
5027
47262
1056
9051
1.18
5.69
3.2
2.4
2370.8
2973.4
umol/l
0.29
962
8141
879
7429
1.20
5.56
1.4
1.4
479.2
542.3
titre
0.49
154
1364
262
1917
1.37
5.45
1.6
1.3
231.4
230.8
u/ml
0.01
161
1140
699
5795
1.22
5.41
2.5
2.4
2.4
2.4
mmol/l
1.62
623
5004
556
4509
1.24
5.33
1.3
1.3
230.1
251.3
u/ml
0.17
507
4159
86
500
1.71
5.29
3.3
2.5
10.4
11.1
%
0.23
61
320
122
776
1.57
5.27
3.3
3.2
25.7
27.6
mu/l
0.11
115
721
4759
45287
1.13
5.19
3.1
3.0
5.5
5.5
mmol/l
0.10
4503
42269
1986
17961
1.13
5.07
1.9
1.8
—
—
—
0
0
747
6279
1.20
5.01
1.2
1.2
—
—
—
0
0
223
1614
1.38
5.00
2.1
1.4
102.6
106.0
u/ml
0.25
46
299
98
600
1.63
4.98
3.4
2.8
1.4
1.2
e9/l
1.45
68
353
11
23
4.74
4.94
2.4
2.7
—
—
—
0
0
1542
13742
1.14
4.91
3.8
2.9
121.4
77.3
e6/l
0.25
1216
10205
232
1704
1.36
4.76
2.0
1.4
15.9
19.8
u/ml
—
9
31
446
3578
1.25
4.74
3.4
2.9
0.2
0.2
g/l
0.03
421
3354
414
3295
1.26
4.71
9.4
4.5
5.0
4.8
kpa
0.72
400
3177
163
1131
1.44
4.67
2.8
2.4
622.4
327.1
ug/l
0.57
151
988
88
534
1.64
4.66
3.5
2.6
35.7
45.2
%
—
7
71
33
144
2.27
4.65
5.0
2.8
7.4
7.4
ph
—
7
36
618
5157
1.20
4.50
2.3
2.0
376.9
387.0
nmol/l
0.59
583
4755
1635
14712
1.13
4.44
3.9
3.3
0.0
0.0
estimate
0.58
573
5633
522
4297
1.22
4.37
1.6
1.5
15.5
15.0
iu/l
0.13
438
3554
460
3739
1.23
4.36
4.3
4.4
0.9
0.7
%
0.51
111
889
82
498
1.64
4.35
3.4
2.9
591.9
539.2
e6/l
0.51
70
403
816
6999
1.18
4.34
3.1
2.6
4.3
4.3
e6/l
0.03
462
3558
280
2145
1.30
4.34
4.1
2.8
21.4
21.1
s
0.76
246
1824
23
88
2.59
4.29
1.4
1.4
—
—
—
0
0
694
5879
1.19
4.28
3.3
3.1
1091.6
761.4
ng/l
1.28
571
4610
616
5172
1.20
4.20
1.6
1.4
—
—
—
0
0
30
132
2.26
4.18
2.2
1.4
—
—
—
0
0
54
296
1.81
4.14
3.8
2.9
232.6
227.7
e6/l
0.03
38
181
145
1010
1.43
4.12
1.2
1.3
294.9
321.5
ug/g
0.69
68
484
80
492
1.62
4.07
3.4
2.9
0.2
0.2
e9/l
0.40
68
407
1135
10030
1.14
4.04
2.3
2.1
185.2
219.5
u/l
0.84
1090
9533
219
1641
1.33
4.00
3.7
4.0
0.4
0.4
g/l
0.01
124
835
424
3451
1.23
3.99
4.5
4.5
0.1
0.2
%
0.41
96
724
135
935
1.44
3.97
1.5
1.5
9.9
11.2
mmol/l
—
9
104
1915
17493
1.12
3.96
4.3
3.3
65.0
67.4
e6/l
0.07
1297
11164
6012
58388
1.16
3.88
10.9
8.7
—
—
—
0
0
929
8123
1.15
3.85
1.3
1.3
7.6
8.9
u/ml
0.31
344
3290
14
43
3.23
3.83
10.5
7.0
5.2
6.3
mmol/l
0.90
14
43
57
326
1.74
3.82
14.6
5.1
11.1
11.4
%
0.22
57
326
57
326
1.74
3.82
1.7
1.4
—
—
—
0
0
38
191
1.97
3.81
1.1
1.1
—
—
—
0
0
38
191
1.97
3.81
1.1
1.0
—
—
—
0
0
49
270
1.80
3.73
2.3
2.8
42.1
43.6
%
0.22
22
88
872
7611
1.15
3.71
1.5
1.5
80488229.8
37731973.2
pmol/l
0.78
779
6586
230
1760
1.30
3.65
2.0
1.9
0.2
0.2
g/l
0.35
216
1676
225
1718
1.31
3.63
2.1
1.4
—
—
—
0
0
1351
12164
1.12
3.56
4.0
3.4
8.2
8.6
mmol/l
1.41
1186
10759
422
3483
1.21
3.50
4.1
4.1
0.5
0.5
%
0.06
84
671
240
1862
1.29
3.45
8.1
3.8
127.7
132.9
g/l
3.40
228
1821
1145
10232
1.13
3.42
1.7
1.6
1.4
1.3
mmol/l
0.62
1042
9035
433
3592
1.21
3.41
4.4
4.4
0.1
0.1
%
0.60
106
832
195
1476
1.32
3.38
12.8
10.6
24.0
24.1
mmol/l
0.12
186
1409
20
81
2.45
3.38
1.5
1.4
17.7
14.6
nmol/l
—
7
20
144
1041
1.38
3.38
1.3
1.3
—
—
—
0
0
233
1807
1.29
3.37
1.9
1.9
1.2
1.2
g/l
0.48
220
1724
611
5230
1.17
3.37
1.4
1.3
—
—
—
0
0
1210
10862
1.12
3.35
5.9
3.8
94.0
94.4
%
0.26
1175
10559
4100
39098
1.10
3.33
4.1
3.7
36.9
36.8
mmol/mol
0.08
3924
37018
272
2157
1.26
3.29
1.3
1.3
1.2
1.0
u/ml
0.09
17
170
39
209
1.85
3.28
5.7
5.5
76.6
3584.9
mg/l
1.34
31
163
536
4553
1.18
3.25
1.5
1.4
—
—
—
0
0
51
299
1.69
3.19
6.8
3.6
—
—
—
0
0
126
901
1.39
3.18
8.5
3.2
23.2
23.9
mmol/l
1.53
114
811
5775
56071
1.13
3.16
9.3
7.6
25.9
25.7
u/l
0.19
5620
54231
977
8691
1.13
3.14
1.3
1.3
18.2
22.4
iu/ml
1.18
283
2392
168
1260
1.33
3.13
1.1
1.1
3.8
13.4
au/ml
—
8
92
518
4414
1.17
3.04
1.5
1.3
—
—
—
0
0
39
215
1.80
3.03
1.4
1.2
—
—
—
0
0
633
5482
1.16
3.02
1.6
1.6
1158.4
1171.6
nmol/l
0.14
498
4240
16
62
2.56
2.97
1.1
1.1
—
—
—
0
0
88
598
1.46
2.96
1.4
1.4
0.4
0.4
g/l
0.08
66
428
176
1341
1.31
2.96
4.8
3.8
24.8
25.0
mmol/l
0.28
168
1294
220
1726
1.27
2.95
1.5
1.6
14.2
8.6
u/ml
—
6
74
144
1067
1.34
2.94
1.3
1.2
—
—
—
0
0
88
599
1.46
2.94
1.4
1.3
2.9
2.8
g/l
0.25
68
431
2579
24193
1.09
2.91
9.7
8.0
0.0
0.0
e9/l
0.67
2101
19843
1374
12516
1.11
2.91
3.6
2.8
0.3
0.3
e6/l
0.12
1058
9139
88
605
1.45
2.80
1.5
1.4
—
—
—
0
0
143
1068
1.33
2.79
3.6
3.6
3.5
3.9
e9/l
1.87
143
1068
87
599
1.44
2.76
1.4
1.3
6.2
6.5
g/l
0.52
64
434
208
1636
1.27
2.76
10.0
4.6
9.6
9.5
kpa
0.26
199
1554
1275
11608
1.11
2.72
1.8
1.7
—
—
—
0
0
145
1091
1.32
2.70
4.4
3.8
51.9
55.7
%
3.33
145
1091
4813
46415
1.09
2.68
3.3
3.0
4.6
4.6
mmol/l
0.44
4613
44160
455
3882
1.17
2.66
10.2
7.0
104.7
105.0
mmol/l
0.79
446
3800
15
60
2.48
2.64
1.1
1.2
—
152.5
—
0
8
79
542
1.45
2.57
3.9
2.8
1.3
1.3
%
0.04
65
432
181
1416
1.27
2.54
1.5
1.4
66.8
87.3
titre
0.93
22
152
182
1425
1.27
2.53
1.9
2.1
1.3
1.3
g/l
0.38
164
1261
1380
12664
1.10
2.50
3.5
2.8
—
—
—
0
0
69
464
1.48
2.50
1.2
1.3
77.3
276.8
titre
4.03
11
98
112
823
1.35
2.47
1.4
1.4
—
—
—
0
0
93
663
1.39
2.47
5.5
3.3
—
—
—
0
0
354
2979
1.19
2.47
15.1
12.1
1.2
1.1
inr
0.61
55
523
124
926
1.33
2.46
1.7
1.7
0.8
0.7
g/l
0.13
98
719
145
1108
1.30
2.45
1.9
1.6
697.1
3103.3
titre
—
7
24
150
1153
1.29
2.43
2.6
2.7
—
—
—
0
0
105
767
1.36
2.41
12.0
4.0
—
—
—
0
0
1800
18934
0.92
2.41
2.1
2.0
—
—
—
0
0
261
2141
1.21
2.40
1.7
1.7
—
—
—
0
0
14
57
2.43
2.39
1.4
1.3
—
—
—
0
0
67
453
1.47
2.38
3.1
3.0
992.1
866.3
e6/l
0.49
20
163
489
4237
1.15
2.37
2.5
2.4
38.1
46.4
u/l
0.31
422
3630
428
3673
1.16
2.36
1.7
1.5
7.9
7.8
u/l
0.05
348
2979
149
1150
1.29
2.35
2.0
2.0
11.4
9.9
mg/l
1.66
141
1087
363
3082
1.18
2.30
11.4
7.1
1.3
1.3
mmol/l
0.48
340
2935
63
425
1.47
2.28
3.9
3.1
—
—
—
0
0
122
921
1.32
2.27
2.0
2.0
3.8
1.9
ug/l
0.76
98
818
49
314
1.55
2.25
1.1
1.1
—
—
—
0
0
58
386
1.49
2.24
6.5
3.4
—
—
—
0
0
4820
46614
1.08
2.24
3.4
3.2
2.8
2.8
mmol/l
0.71
4604
44008
1341
12353
1.09
2.23
2.8
2.5
33.8
59.5
ng/l
0.56
618
5055
11
41
2.66
2.23
1.3
1.3
—
—
—
0
0
7
18
3.85
2.23
1.4
1.6
—
—
—
0
0
589
5197
1.13
2.20
1.2
1.2
—
—
—
0
0
513
4489
1.14
2.18
1.4
1.4
—
—
—
0
0
58
389
1.48
2.17
1.6
1.4
—
—
—
0
0
162
1279
1.26
2.16
11.5
6.9
—
—
—
0
0
335
2843
1.18
2.15
8.8
4.0
5.1
5.1
kpa
0.39
322
2685
19
93
2.03
2.15
1.1
1.7
—
—
—
0
0
47
302
1.54
2.15
1.4
1.4
—
—
—
0
0
6453
63317
1.16
2.14
17.5
14.0
261.5
262.8
e9/l
0.95
6326
61762
34
202
1.67
2.13
5.5
6.7
54.8
49.9
g/mol
0.09
29
182
67
465
1.43
2.11
1.4
1.5
—
—
—
0
0
6463
63430
1.16
2.09
17.5
14.0
6.7
6.8
e9/l
1.99
6329
61783
2657
25197
1.07
2.09
4.4
3.9
—
—
—
0
0
6459
63389
1.16
2.08
17.4
13.9
29.9
29.8
pg
1.30
6396
62665
873
7905
1.11
2.08
4.9
4.4
11.3
12.7
mg/mmol
0.39
616
5541
6458
63387
1.16
2.03
17.4
13.9
89.1
89.0
fl
0.84
6395
62663
16
75
2.11
2.03
1.2
1.1
127.5
224.4
mg/l
0.24
11
46
242
2010
1.20
2.01
2.9
2.2
66.6
67.4
g/l
1.18
233
1880
801
7235
1.11
2.01
3.1
2.5
1.1
1.1
e6/l
0.11
452
3798
6459
63404
1.16
2.00
17.4
14.0
4.6
4.6
e12/l
1.54
6326
61772
4756
46047
1.07
1.99
3.2
3.0
1.5
1.5
mmol/l
0.47
4554
43710
52
350
1.47
1.95
1.2
1.2
—
—
—
0
0
30
178
1.67
1.91
1.5
1.2
—
—
—
0
0
518
5729
0.89
1.91
1.4
1.4
—
—
—
0
0
18
91
1.96
1.89
1.8
1.5
—
—
—
0
0
329
2822
1.16
1.89
9.0
4.0
7.4
7.4
ph
0.05
31
298
1436
13361
1.08
1.88
4.5
4.1
—
—
—
0
0
310
2648
1.17
1.88
1.7
1.4
—
—
—
0
0
90
672
1.33
1.87
1.7
1.7
14922.8
12785.4
e6/l
0.14
69
495
1715
16072
1.08
1.85
3.1
2.7
—
—
—
0
0
135
1067
1.26
1.83
1.1
1.1
—
—
—
0
0
22
121
1.80
1.82
1.0
1.0
0.1
0.9
u/ml
—
10
82
150
1202
1.24
1.81
1.1
1.1
4.5
2.4
u/ml
0.67
73
583
178
1453
1.22
1.80
8.5
3.6
0.7
0.7
%
0.09
167
1413
838
7637
1.10
1.78
4.1
3.6
981.3
326.3
mg/l
1.98
589
5314
13
60
2.15
1.73
1.2
1.0
0.2
0.8
u/ml
—
6
24
63
451
1.39
1.73
1.3
1.3
0.5
0.6
u/ml
0.05
26
137
21
116
1.79
1.73
3.6
3.6
0.3
3.9
%
—
7
31
435
3836
1.13
1.70
3.2
3.3
4.7
4.7
pmol/l
0.04
391
3480
85
640
1.32
1.70
1.1
1.1
1.5
1.4
g/l
0.86
79
582
6458
63448
1.14
1.69
17.6
14.1
135.3
135.6
g/l
1.21
6397
62722
53
371
1.42
1.66
1.2
1.1
—
—
—
0
0
95
730
1.29
1.65
2.5
2.4
—
—
—
0
0
16
82
1.93
1.64
1.0
1.0
1003.8
760.3
ng/l
—
10
55
45
306
1.46
1.64
4.0
3.8
—
—
—
0
0
10
42
2.36
1.64
2.0
1.8
104.7
102.3
ng/l
—
10
42
20
111
1.79
1.63
2.4
1.9
—
—
—
0
0
19
104
1.81
1.62
1.7
1.2
—
—
—
0
0
15
76
1.96
1.59
1.6
1.6
2.8
450854.3
nmol/l
0.72
15
59
11
49
2.22
1.59
1.4
1.6
8.4
13.7
g/l
—
6
38
419
4632
0.89
1.58
1.2
1.3
—
—
—
0
0
12
56
2.12
1.57
1.1
1.1
0.2
1.2
u/ml
—
6
26
56
401
1.39
1.56
2.1
2.1
—
—
—
0
0
38
253
1.49
1.55
1.2
1.1
—
—
—
0
0
231
1963
1.17
1.55
3.4
3.9
3.8
39.5
ug/l
1.19
171
1413
96
746
1.28
1.55
4.5
2.9
33.9
32.1
umol/l
0.31
85
647
4546
44106
1.06
1.53
3.0
2.8
1.2
1.2
mmol/l
0.14
4346
41901
458
4082
1.12
1.53
1.1
1.2
647.3
186.0
titre
0.82
11
124
243
2077
1.16
1.52
1.1
1.1
—
—
—
0
0
16
85
1.87
1.50
1.0
1.0
230.3
280.7
ng/l
—
10
59
7
27
2.57
1.49
2.0
2.3
—
—
—
0
0
6
21
2.83
1.49
1.3
1.2
—
—
—
0
0
1639
15454
1.07
1.47
2.5
2.1
—
—
—
0
0
128
1036
1.23
1.47
1.3
1.3
3.7
4.4
u/ml
0.35
63
493
129
1045
1.23
1.47
1.1
1.1
—
—
—
0
0
28
177
1.57
1.45
2.0
1.6
—
—
—
0
0
15
79
1.88
1.45
3.7
2.4
—
—
—
0
0
101
799
1.26
1.43
3.7
3.7
265.7
1824.0
u/ml
0.66
91
681
422
4628
0.90
1.41
1.5
1.5
—
—
—
0
0
28
179
1.55
1.40
2.3
2.1
—
—
—
0
0
145
1200
1.20
1.35
1.9
1.7
—
—
—
0
0
40
278
1.43
1.35
2.8
2.9
0.2
0.2
e9/l
0.04
40
272
6
23
2.58
1.35
1.5
1.3
—
—
—
0
0
56
413
1.35
1.34
1.1
1.1
38.2
27.3
u/ml
0.10
38
274
19
111
1.70
1.34
7.3
5.1
23.9
24.5
mmol/l
0.29
14
105
318
2799
1.13
1.34
1.4
1.4
—
—
—
0
0
716
7633
0.92
1.34
1.4
1.4
—
—
—
0
0
51
371
1.36
1.33
4.9
3.0
—
—
—
0
0
64
483
1.31
1.32
3.8
2.8
8.3
1.5
ratio
0.47
11
53
65
492
1.31
1.31
4.3
2.9
52.0
63.4
mg/l
0.25
55
398
79
614
1.28
1.31
2.4
1.7
29.0
32.7
iu/ml
—
5
36
170
1432
1.18
1.31
1.4
1.3
44.4
31.5
u/ml
0.28
13
80
65
493
1.31
1.30
4.3
2.9
47.9
35.2
mg/l
0.54
56
400
12
61
1.95
1.29
1.1
1.1
—
—
—
0
0
772
7130
1.08
1.26
1.5
1.5
—
—
—
0
0
123
1011
1.21
1.25
1.2
1.2
—
—
—
0
0
141
1174
1.19
1.25
1.3
1.3
38.6
38.7
u/ml
0.00
12
94
59
445
1.32
1.24
3.5
4.3
9.6
8.5
mg/l
0.53
50
368
17
99
1.70
1.23
1.1
1.3
—
—
—
0
0
1315
12386
1.06
1.22
1.5
1.5
—
—
—
0
0
22
138
1.58
1.21
1.0
1.1
—
—
—
0
0
23
146
1.56
1.21
2.3
2.2
—
—
—
0
0
5
19
2.61
1.20
1.0
1.9
—
—
—
0
0
87
694
1.24
1.19
1.3
1.3
30.4
38.3
u/ml
0.17
11
37
155
1309
1.18
1.19
1.4
1.3
35.8
15.1
u/ml
0.64
21
182
57
431
1.31
1.19
1.1
1.1
1281.7
1493.8
miu/ml
0.78
57
431
163
1873
0.86
1.16
3.5
2.5
—
—
—
0
0
88
1065
0.82
1.12
5.0
3.6
7.4
7.4
ph
0.04
74
909
3854
37403
1.05
1.09
3.3
2.8
36.8
32.2
u/l
1.97
3712
35766
76
929
0.81
1.08
5.5
3.6
1.9
1.9
mmol/l
0.09
44
510
241
2122
1.13
1.06
9.2
4.4
—
—
—
0
0
174
1499
1.15
1.06
2.3
2.1
—
—
—
0
0
41
301
1.35
1.06
2.1
2.6
10.1
9.7
mg/l
0.17
31
252
151
1287
1.17
1.06
1.4
1.3
6.8
9.8
u/ml
0.25
17
121
148
1260
1.17
1.06
4.5
2.7
—
—
—
0
0
12
66
1.80
1.05
1.8
1.7
—
—
—
0
0
11
59
1.85
1.04
1.4
3.6
—
—
—
0
0
21
136
1.53
1.04
1.3
1.4
—
—
—
0
0
419
4513
0.91
1.04
1.5
1.5
—
—
—
0
0
420
4521
0.91
1.03
1.5
1.5
—
—
—
0
0
25
169
1.47
1.02
1.8
1.9
—
—
—
0
0
34
244
1.38
1.02
6.0
7.2
—
—
—
0
0
22
145
1.50
1.01
3.0
2.9
8.1
9.5
mmol/l
1.68
14
114
164
1414
1.15
1.00
2.3
1.8
—
—
—
0
0
36
262
1.36
1.00
1.3
1.4
30809.2
64148.0
e6/l
0.50
22
181
14
83
1.67
0.98
2.5
3.0
201.1
178.3
ug/g
0.28
14
78
58
454
1.27
0.97
1.1
1.2
—
—
—
0
0
33
238
1.37
0.97
1.1
1.1
—
—
—
0
0
62
491
1.25
0.95
1.2
1.2
—
—
—
0
0
25
172
1.44
0.95
1.3
1.4
8319.0
3474.9
e6/l
0.36
19
114
50
387
1.28
0.93
1.4
1.8
21.2
21.9
umol/l
0.07
50
371
75
609
1.22
0.93
1.1
1.4
—
—
—
0
0
27
190
1.41
0.92
1.5
1.3
—
—
—
0
0
89
1049
0.84
0.91
1.5
1.4
30.1
32.8
nmol/l
0.38
82
975
161
1399
1.14
0.91
1.2
1.2
—
—
—
0
0
28
199
1.39
0.91
2.0
2.2
1.1
1.4
nmol/l
0.50
20
162
60
478
1.24
0.89
2.0
2.1
—
0.7
—
0
9
5
101
0.49
0.89
1.2
1.0
—
—
—
0
0
392
3582
1.09
0.89
2.6
2.1
4.2
4.2
e9/l
0.17
324
3000
6
29
2.05
0.88
1.0
1.2
—
—
—
0
0
756
7904
0.94
0.88
2.0
2.1
—
—
—
0
0
21
142
1.47
0.88
1.0
1.1
—
137.1
—
0
7
100
1162
0.85
0.88
1.7
1.9
—
—
—
0
0
204
1806
1.12
0.87
1.3
1.1
—
—
—
0
0
18
118
1.51
0.87
4.9
3.3
47.0
48.0
%
0.10
18
112
47
365
1.28
0.86
2.4
2.0
—
—
—
0
0
81
669
1.20
0.86
2.4
2.2
—
—
—
0
0
220
1959
1.12
0.85
2.1
2.1
8.0
6.7
ug/l
0.31
200
1704
2180
22169
0.96
0.83
1.7
1.8
—
—
—
0
0
6
31
1.92
0.83
1.3
1.5
371.9
561.3
nmol/l
—
6
31
36
463
0.77
0.83
1.6
1.5
—
—
—
0
0
68
555
1.21
0.82
1.2
1.2
—
—
—
0
0
17
247
0.68
0.82
1.3
1.2
—
—
—
0
0
52
413
1.25
0.81
2.6
3.5
133.0
115.2
au/ml
—
8
62
73
602
1.20
0.80
5.7
2.8
—
—
—
0
0
60
485
1.23
0.80
1.1
1.1
5.4
6.1
iu/ml
0.19
12
113
23
162
1.41
0.80
1.2
1.1
—
—
—
0
0
191
1696
1.12
0.79
1.6
1.6
7.7
7.4
mmol/l
0.76
103
1021
11
65
1.68
0.79
7.8
4.9
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
0.0
—
0
15
326
2976
1.09
0.78
1.1
1.1
—
—
—
0
0
13
81
1.59
0.78
1.2
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
1.0
—
—
—
0
0
6
33
1.80
0.78
1.3
1.3
18.0
14.0
pmol/l
—
6
27
5
98
0.50
0.77
3.8
2.3
—
—
—
0
0
9
52
1.71
0.75
1.8
2.1
—
—
—
0
0
13
82
1.57
0.75
1.6
2.9
1.2
1.2
umol/l
0.00
13
77
97
827
1.16
0.75
5.1
5.4
404.1
375.3
umol/l
1.24
89
724
16
230
0.69
0.75
1.4
1.2
—
—
—
0
0
873
8260
1.05
0.74
2.3
2.4
7135.1
7104.7
u/l
0.01
320
3266
32
242
1.31
0.74
1.3
1.1
—
—
—
0
0
470
4366
1.07
0.74
1.3
1.3
240.4
233.0
miu/ml
0.16
216
2222
246
2228
1.10
0.72
1.6
1.7
—
—
—
0
0
5
25
1.98
0.72
1.2
1.2
—
—
—
0
0
52
421
1.22
0.71
1.2
1.4
72.7
51.9
pmol/l
0.43
17
119
277
2974
0.92
0.71
1.2
1.2
—
—
—
0
0
73
612
1.18
0.70
1.3
1.3
—
—
—
0
0
62
512
1.20
0.70
1.2
1.3
—
—
—
0
0
126
1102
1.13
0.70
1.2
1.1
—
—
—
0
0
11
168
0.65
0.70
2.0
1.7
—
—
—
0
0
37
459
0.80
0.68
1.3
1.6
5.6
5.8
mmol/l
0.30
26
387
192
1726
1.10
0.67
1.2
1.1
—
—
—
0
0
561
5262
1.06
0.67
3.6
3.5
2.2
1.8
ug/l
0.37
517
4791
21
152
1.37
0.65
1.3
1.4
31936.0
32008.4
e6/l
0.00
15
87
557
5228
1.06
0.65
1.6
1.6
317.4
320.8
mu/l
0.07
513
4675
148
1316
1.12
0.64
2.2
1.5
3.4
3.5
mmol/l
2.13
138
1238
65
545
1.18
0.64
3.5
4.0
58.8
132.8
u/ml
1.01
24
176
43
346
1.23
0.64
1.1
1.1
17.7
15.8
u/ml
—
9
74
29
222
1.29
0.64
1.0
1.1
—
—
—
0
0
424
3950
1.07
0.64
2.3
2.0
10.2
10.2
nmol/l
0.02
373
3517
17
233
0.72
0.63
3.2
2.8
—
—
—
0
0
5
29
1.71
0.63
1.0
1.1
—
—
—
0
0
38
303
1.24
0.61
1.5
1.6
1.4
2.2
nmol/l
0.58
28
242
5652
55561
1.04
0.61
13.6
10.2
40.1
40.2
%
0.50
4782
46443
8
50
1.58
0.60
1.4
2.3
—
—
—
0
0
147
1314
1.11
0.59
2.4
1.6
23.8
18.7
e6/l
0.18
113
1016
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
64
541
1.17
0.59
1.4
1.3
—
—
—
0
0
66
756
0.86
0.56
1.7
2.7
—
—
—
0
0
138
1507
0.90
0.55
1.1
1.1
—
—
—
0
0
90
1007
0.88
0.55
3.5
2.9
33.0
23.6
mg/l
1.07
54
617
146
1315
1.10
0.53
2.5
1.7
444.2
3703.1
e6/l
0.61
120
1064
17
124
1.36
0.53
1.3
1.4
—
—
—
0
0
353
3297
1.06
0.52
1.2
1.2
—
—
—
0
0
6
39
1.52
0.52
1.3
1.1
—
—
—
0
0
40
473
0.84
0.50
1.2
1.1
—
—
—
0
0
76
662
1.14
0.50
4.1
3.6
17.6
54.7
u/ml
0.62
68
560
49
568
0.85
0.50
1.0
1.0
—
—
—
0
0
139
1255
1.10
0.49
2.4
1.7
—
—
—
0
0
42
350
1.19
0.48
2.0
3.5
112.5
174.6
umol/l
0.72
23
189
139
1503
0.91
0.48
1.1
1.1
—
—
—
0
0
350
3282
1.06
0.47
3.6
3.2
—
—
—
0
0
266
2473
1.07
0.47
2.3
2.2
33.1
32.7
u/ml
0.02
254
2385
300
2802
1.06
0.46
4.3
3.3
1.2
1.2
mmol/l
0.55
260
2400
270
2516
1.06
0.45
1.1
1.1
2.5
2.1
u/ml
0.22
134
1192
159
1703
0.92
0.45
1.5
1.6
—
—
—
0
0
10
68
1.46
0.45
1.3
1.6
—
—
—
0
0
163
1492
1.08
0.44
2.2
1.6
398.1
434.4
mg/l
0.49
154
1420
26
208
1.24
0.44
1.2
1.4
134.1
133.7
nmol/l
0.01
26
208
278
2597
1.06
0.44
1.6
1.7
—
—
—
0
0
2682
26169
1.02
0.43
2.2
2.2
—
—
—
0
0
63
550
1.14
0.42
2.0
1.8
107.2
58.7
mu/l
0.53
57
505
10
69
1.44
0.42
1.0
1.1
10.0
8.0
mmol/l
—
5
10
38
319
1.18
0.42
2.8
2.7
51.8
53.5
%
0.17
23
207
5
32
1.55
0.42
1.0
1.2
—
—
—
0
0
35
292
1.19
0.41
1.7
2.3
—
—
—
0
0
39
329
1.17
0.41
2.6
1.4
—
—
—
0
0
14
104
1.33
0.40
2.1
2.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
3.3
—
0
11
49
422
1.15
0.40
1.1
1.1
—
—
—
0
0
24
193
1.23
0.40
1.2
1.1
—
—
—
0
0
24
193
1.23
0.40
1.2
1.1
—
—
—
0
0
584
5576
1.04
0.40
2.4
2.2
—
—
—
0
0
612
5849
1.04
0.40
1.2
1.3
142.5
143.1
iu/ml
0.01
239
2156
5
34
1.46
0.40
1.0
1.0
—
—
—
0
0
53
460
1.14
0.39
1.2
1.1
1.0
1.1
ratio
0.13
17
176
17
131
1.29
0.39
1.1
1.0
0.0
2.5
u/ml
—
6
87
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
7.9
—
0
8
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
33
276
1.18
0.38
1.1
1.1
0.1
4.0
nmol/l
—
5
48
5
36
1.38
0.38
3.0
4.2
—
—
—
0
0
5
36
1.38
0.38
4.8
1.3
—
—
—
0
0
61
676
0.89
0.36
2.6
2.6
91.5
105.5
ug/min
0.16
43
447
45
389
1.15
0.36
1.3
1.2
—
—
—
0
0
32
269
1.18
0.36
1.3
1.6
39.0
41.0
%
0.11
22
178
233
2183
1.06
0.36
1.4
1.3
—
—
—
0
0
283
2667
1.05
0.36
1.3
1.3
4.0
4.0
ug/l
0.08
273
2558
70
624
1.11
0.35
1.6
1.8
39.2
38.9
g/l
0.15
61
564
940
9075
1.03
0.35
2.8
2.6
—
—
—
0
0
39
335
1.15
0.34
1.3
1.2
—
—
—
0
0
104
948
1.09
0.34
2.6
2.1
131.8
132.7
g/l
0.17
77
755
6
44
1.35
0.34
1.0
1.1
—
—
—
0
0
61
672
0.90
0.34
1.0
1.1
—
—
—
0
0
10
132
0.75
0.34
1.2
1.1
—
—
—
0
0
12
154
0.77
0.34
1.5
1.4
—
—
—
0
0
75
674
1.10
0.34
3.4
2.0
—
—
—
0
0
31
262
1.17
0.33
1.8
2.2
—
—
—
0
0
234
2199
1.06
0.33
1.1
1.1
2.3
3.1
u/ml
0.46
75
635
42
364
1.14
0.33
1.3
1.7
50.6
49.8
%
0.05
31
248
45
393
1.13
0.32
1.1
1.1
—
—
—
0
0
720
6936
1.03
0.32
2.0
2.0
—
—
—
0
0
407
4180
0.96
0.32
1.4
1.6
—
—
—
0
0
21
172
1.21
0.31
2.0
1.7
—
—
—
0
0
10
130
0.76
0.31
1.7
1.2
—
—
—
0
0
31
265
1.16
0.30
2.3
3.0
—
—
—
0
0
183
1717
1.06
0.29
1.1
1.2
—
—
—
0
0
50
444
1.12
0.29
2.1
2.1
70.4
73.7
mmol/l
0.19
44
371
23
193
1.18
0.28
1.2
1.1
—
—
—
0
0
27
230
1.16
0.28
1.9
2.1
2.5
1.4
g/24h
—
6
27
57
620
0.91
0.27
1.1
1.1
—
—
—
0
0
8
65
1.22
0.27
1.3
1.1
—
2.0
—
0
10
73
783
0.92
0.26
3.1
2.3
17.7
17.4
%
0.25
41
372
172
1619
1.05
0.26
1.1
1.1
10.2
7.3
u/ml
0.43
91
777
5
71
0.70
0.26
1.2
1.4
—
90.9
—
0
6
5
73
0.68
0.26
1.4
1.2
—
—
—
0
0
19
158
1.19
0.26
1.3
1.4
—
—
—
0
0
545
5255
1.03
0.25
1.2
1.2
—
—
—
0
0
41
364
1.12
0.25
1.3
1.2
2.7
8.6
u/ml
—
7
42
75
801
0.93
0.25
7.0
3.8
3.8
3.8
mmol/l
0.05
70
741
53
575
0.91
0.25
3.5
3.0
—
—
—
0
0
11
136
0.80
0.24
2.2
2.3
—
—
—
0
0
10
77
1.29
0.24
7.0
6.1
—
—
—
0
0
23
263
0.87
0.24
2.8
2.1
—
—
—
0
0
1205
11741
1.02
0.24
2.5
2.0
—
—
—
0
0
57
517
1.09
0.24
1.5
1.3
—
—
—
0
0
147
1384
1.05
0.23
1.0
1.1
0.3
0.4
u/ml
0.19
40
337
5
38
1.30
0.23
11.0
8.2
—
—
—
0
0
94
874
1.07
0.22
1.3
1.3
—
—
—
0
0
379
3645
1.03
0.22
1.2
1.2
—
—
—
0
0
5
40
1.24
0.22
1.0
1.2
—
—
—
0
0
69
635
1.08
0.22
1.1
1.1
0.3
1.4
u/ml
0.95
18
122
5
41
1.21
0.21
1.0
1.0
13.5
16.0
u/ml
—
5
30
5
41
1.21
0.21
4.8
1.3
—
—
—
0
0
27
236
1.13
0.21
1.3
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
0.1
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
196.7
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
493
4995
0.98
0.20
3.9
2.8
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
37
332
1.10
0.20
1.1
1.1
38.0
7.5
u/ml
0.64
27
247
375
3615
1.03
0.20
2.3
2.3
19.6
19.7
au/ml
0.01
19
273
185
1762
1.04
0.19
1.1
1.1
6.3
5.1
u/ml
0.13
92
801
71
658
1.07
0.19
2.3
1.7
—
—
—
0
0
316
3218
0.97
0.19
2.5
2.5
—
—
—
0
0
56
516
1.07
0.18
1.4
1.5
475.2
385.2
pmol/l
0.55
43
424
19
164
1.15
0.18
1.3
1.5
—
—
—
0
0
7
57
1.22
0.18
2.1
2.1
—
—
—
0
0
157
1615
0.96
0.17
2.2
2.1
4.4
3.9
iu/l
0.24
78
664
10
81
1.22
0.17
1.7
1.9
—
—
—
0
0
18
156
1.14
0.16
6.3
2.3
0.8
2.0
mmol/l
2.32
13
121
34
308
1.09
0.16
1.1
1.1
—
—
—
0
0
527
5312
0.98
0.16
3.5
3.2
—
—
—
0
0
293
2974
0.97
0.16
2.4
2.4
0.6
0.7
ug/l
0.09
158
1576
2105
20681
1.01
0.15
1.8
1.8
—
—
—
0
0
40
427
0.93
0.15
1.4
1.3
—
—
—
0
0
17
148
1.14
0.15
1.2
1.2
—
—
—
0
0
7
86
0.81
0.14
1.0
1.1
—
—
—
0
0
43
455
0.94
0.14
2.7
2.1
287.1
287.8
mosm/kgh2o
0.10
38
358
75
708
1.05
0.13
1.1
1.1
2.5
3.2
u/ml
0.17
39
277
58
544
1.06
0.13
1.4
1.6
—
—
—
0
0
10
84
1.18
0.12
1.1
1.0
0.1
0.5
u/ml
—
10
72
723
7071
1.01
0.12
2.3
2.0
—
—
—
0
0
233
2254
1.02
0.12
1.1
1.1
7.4
7.8
u/ml
0.13
150
1361
1890
18831
0.99
0.12
1.8
1.8
—
—
—
0
0
10
115
0.86
0.12
1.0
1.1
—
—
—
0
0
668
6531
1.01
0.12
2.3
2.1
—
—
—
0
0
314
3168
0.98
0.12
3.5
3.1
—
—
—
0
0
17
187
0.90
0.11
1.1
1.0
0.0
1.5
u/ml
—
7
108
724
7088
1.01
0.11
2.3
2.1
—
—
—
0
0
10
85
1.16
0.11
1.1
1.1
—
—
—
0
0
72
684
1.04
0.10
1.0
1.1
1.7
6.7
u/ml
0.84
39
233
19
206
0.91
0.10
1.0
1.1
—
—
—
0
0
11
95
1.15
0.10
1.3
1.1
—
9.8
u/ml
—
0
5
5
45
1.10
0.09
1.8
2.8
33.7
51.1
pmol/l
—
5
38
10
113
0.88
0.09
1.2
1.2
—
—
—
0
0
19
172
1.09
0.09
3.5
2.4
—
—
—
0
0
10
86
1.15
0.09
1.2
1.2
—
—
—
0
0
10
86
1.15
0.09
1.2
1.2
—
—
—
0
0
10
86
1.15
0.09
1.2
1.2
—
—
—
0
0
121
1165
1.03
0.09
1.7
1.8
165.7
172.3
pmol/l
0.27
114
1108
5
47
1.05
0.09
1.8
3.7
0.6
1.9
mg/l
—
5
31
165
1598
1.02
0.09
1.2
1.3
—
—
—
0
0
19
204
0.92
0.08
1.0
1.1
—
—
—
0
0
56
532
1.04
0.08
2.6
2.7
1.3
1.4
mmol/l
0.77
56
516
52
537
0.96
0.08
1.0
1.0
—
—
—
0
0
6
56
1.06
0.08
1.0
1.0
—
—
—
0
0
5
62
0.80
0.08
1.0
1.2
—
—
—
0
0
44
416
1.05
0.08
1.0
1.0
17.1
8.3
u/ml
—
7
47
7
63
1.10
0.08
1.0
1.1
—
—
—
0
0
17
183
0.92
0.08
1.1
1.0
38.3
3.3
u/ml
—
7
101
99
1006
0.97
0.07
1.1
1.1
53.1
1349.8
iu/ml
0.81
18
316
6
73
0.81
0.07
11.3
5.1
—
—
—
0
0
8
77
1.03
0.07
1.1
1.2
—
—
—
0
0
18
165
1.08
0.07
1.1
1.1
—
—
—
0
0
10
88
1.13
0.07
1.1
1.1
—
—
—
0
0
33
311
1.05
0.07
1.2
1.2
—
—
—
0
0
220
2146
1.02
0.06
1.1
1.1
0.9
1.5
u/ml
1.74
122
1090
715
7029
1.01
0.06
2.3
2.1
—
—
—
0
0
135
1361
0.98
0.06
1.3
1.4
12.3
13.7
u/l
0.40
123
1188
194
1893
1.01
0.06
1.7
1.6
0.4
0.4
nmol/l
0.01
154
1597
16
170
0.93
0.05
1.0
1.1
—
—
—
0
0
21
196
1.06
0.05
3.2
2.9
0.7
0.9
nmol/l
1.15
16
150
88
889
0.98
0.05
3.6
2.7
0.9
0.8
nmol/l
0.41
78
756
13
139
0.93
0.05
1.2
2.0
3.7
3.9
nmol/l
0.04
13
131
821
8166
0.99
0.04
1.2
1.2
—
—
—
0
0
18
189
0.94
0.04
1.3
2.4
—
28.0
—
0
25
51
491
1.03
0.04
3.7
5.2
6.7
6.6
mmol/l
0.07
38
383
36
369
0.97
0.04
1.3
1.1
—
—
—
0
0
57
550
1.03
0.04
1.3
1.2
—
—
—
0
0
31
319
0.96
0.04
5.2
6.2
—
—
—
0
0
31
319
0.96
0.04
2.6
3.1
—
—
—
0
0
114
1146
0.98
0.04
6.7
4.8
—
—
—
0
0
94
915
1.02
0.04
5.4
3.3
—
—
—
0
0
26
247
1.04
0.03
1.6
1.6
2.4
3.7
u/field
0.40
19
172
55
556
0.98
0.03
1.4
1.4
74.3
73.4
%
0.26
55
525
121
1186
1.01
0.02
1.6
1.6
6.9
6.4
mmol/l
0.95
84
821
67
673
0.99
0.02
1.1
1.2
26.0
38.0
mg/l
4.30
56
554
11
102
1.07
0.02
1.0
1.1
—
—
—
0
0
59
576
1.01
0.01
1.9
1.5
1.4
1.3
promille
0.15
50
436
31
300
1.02
0.01
1.5
1.6
—
—
—
0
0
72
720
0.99
0.01
4.5
2.8
—
—
—
0
0
12
125
0.95
0.01
1.2
1.1
7.1
12.7
u/ml
—
6
90
10
105
0.94
0.01
1.1
1.0
—
—
—
0
0
54
541
0.99
0.00
1.4
1.4
450.3
497.4
mu/l
0.31
54
510
10
99
1.00
0.00
1.7
1.6
—
—
—
0
0
10
99
1.00
0.00
1.5
1.1
—
—
—
0
0
32
321
0.99
0.00
1.2
1.1
—
—
—
0
0
48
477
1.00
0.00
2.9
2.7
6.6
6.9
mmol/l
0.32
48
468
66
649
1.01
0.00
1.1
1.1
176.6
214.4
mg/l
2.13
57
564
11
109
1.00
0.00
9.0
3.8
—
—
—
0
0
17
172
0.98
0.00
1.1
1.1
—
—
—
0
0
24
236
1.01
0.00
1.7
1.5
1694.3
2167.1
ml
—
6
30
13
128
1.01
0.00
1.1
1.2
—
—
—
0
0
23
224
1.02
0.00
2.2
2.5
35.2
36.4
mmol/l
0.09
23
215
48
471
1.01
0.00
1.1
1.3
1.9
1.7
mmol/l
0.20
42
438
21
205
1.01
0.00
1.0
1.1
—
—
—
0
0
257
2548
1.00
0.00
2.8
2.4
6.0
5.3
umol/l
0.26
203
1899
28
274
1.01
0.00
2.8
2.0
2.1
2.2
u/field
0.09
15
145
26
258
1.00
0.00
1.2
1.3
9.6
9.0
u/ml
—
5
64
16
162
0.98
0.00
1.4
1.4
—
—
—
0
0
314
3104
1.00
0.00
3.3
2.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
672.3
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.4
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.6
—
—
—
0
0
7
70
0.99
0.00
1.1
1.5
80.7
84.6
umol/l
—
7
65
0
6
0.00
0.00
0.0
1.0
—
1.2
—
0
6
0
5
0.00
0.00
0.0
1.0
—
12.2
—
0
5
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1258.0
—
0
5
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
177.2
—
0
6
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
10.1
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_ERUPTION and mortality.

Females

Parameter HR [95% CI] p-value
K11_ERUPTION 1.532 [1.23, 1.91] < 0.001
Birth year 0.997 [0.99, 1.01] 0.428

During the follow-up period (1.1.1998 — 31.12.2019), 429 out of 41748 females with K11_ERUPTION died.

Males

Parameter HR [95% CI] p-value
K11_ERUPTION 1.505 [1.21, 1.87] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 734 out of 31671 males with K11_ERUPTION died.

Mortality risk

Mortality risk for people of age

years, who have K11_ERUPTION.

N-year risk Females Males
1 0.201% 0.285%
5 0.977% 1.596%
10 2.308% 4.115%
15 4.4% 7.761%
20 7.646% 12.752%

Relationships between endpoints

Index endpoint: K11_ERUPTION – Tooth eruption problems

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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