info icon

This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_NSCLC_ADENO_EXALLC for full statistics.

Non-small cell lung cancer, adenocarcinoma

C3_NSCLC_ADENO

non-small cell lung carcinoma: A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • HLP_C3_NSCLC_ADENO
2148

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C34
  • Cause of death: ICD-9 162
  • Cause of death: ICD-8 162
  • Cancer registry: Topography ICD-O-3 C34
  • Cancer registry: Morphology ICD-O-3 8140
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

2148

4. Check minimum number of events

None

2148

5. Include endpoints

2148

6. Filter based on genotype QC (FinnGen only)

2064

Control definitions (FinnGen only)

Control conditions
not HLP_C3_NSCLC_ADENO

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2064 774 1290
Unadjusted period prevalence (%) 0.52 0.30 0.65
Median age at first event (years) 70.42 69.09 71.22

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2148
Matched controls
21478
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
371.6
323.0
965
47
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
63.1
323.0
493
101
8140/3-C34.3
ICD-O-3
Adenocarcinoma, NOS, of lower lobe, lung
5738.3
323.0
466
*
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
133.8
323.0
446
42
H02AB02
ATC
dexamethasone; systemic
9.8
323.0
814
1255
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
31.5
323.0
710
331
8140/3-C34.1
ICD-O-3
Adenocarcinoma, NOS, of upper lobe, lung
11257.7
323.0
755
*
130
Kela drug reimbursment
Malignant tumour
20.8
323.0
1197
1223
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
20.4
323.0
1280
1449
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
+∞
323.0
831
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
12.0
323.0
861
1130
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
335.3
323.0
604
25
C34.82
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary adenocarcinoma
409.5
323.0
348
10
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
26.9
263.7
372
166
A03FA01
ATC
metoclopramide; systemic, rectal
5.6
259.8
986
2830
WF049
NOMESCO Finland
Radiotherapy of metastasis
14.1
227.4
409
353
L01CA04
ATC
vinorelbine; systemic
67.1
221.1
255
43
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
19.5
217.2
340
205
C34.92
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary adenocarcinoma
325.2
205.1
205
7
A04AA01
ATC
ondansetron; systemic, rectal
8.5
197.2
470
683
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
32.5
195.5
261
91
N02AA05
ATC
oxycodone; systemic
4.8
189.9
784
2294
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
8.2
188.7
461
693
GDC00
NOMESCO Finland
Lobectomy of lung
60.5
185.8
218
40
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
25.9
172.7
245
106
Z51.5
ICD-10 Finland
Palliative care
6.9
164.9
456
810
JN4BD
NOMESCO Finland
Extensive body CT
5.0
158.9
603
1567
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
34.0
139.7
184
59
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
31.3
136.9
184
64
GD1AD
NOMESCO Finland
Thorax CT examination
7.9
131.6
322
468
WF004
NOMESCO Finland
Palliative radiotherapy
12.7
126.1
234
205
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
122.3
1315
7488
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
19.9
122.2
188
103
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.6
119.3
298
444
WZC30
NOMESCO Finland
Teaching
4.1
119.2
554
1695
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.9
116.0
575
1856
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
19.6
114.5
177
98
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.4
110.8
454
1224
R84
ICPC
Malignant neoplasm bronchus/lung
54.8
108.2
129
25
C34.22
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung adenocarcinoma
231.6
107.7
110
5
155
Kela drug reimbursment
Afatinib and gefitinib
527.1
102.5
101
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
11.7
100.2
192
178
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
17.2
98.9
160
100
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
7.8
97.8
238
337
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
21.9
93.0
138
67
191
Kela drug reimbursment
Erlotinib
105.9
92.8
101
10
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
87.6
592
2352
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
24.5
87.3
125
54
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
20.2
87.3
133
70
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
6.2
86.6
251
452
1BA04
NOMESCO Finland
NA
221.0
82.9
85
*
WF002
NOMESCO Finland
Radical radiotherapy
4.6
76.6
287
690
B01AB05
ATC
enoxaparin; parenteral
2.5
76.4
883
4757
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
5.9
75.1
225
420
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
8.8
73.2
163
198
R03BB04
ATC
tiotropium bromide; inhalant
3.2
73.0
450
1650
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
72.3
824
4372
L01XE03
ATC
[U] erlotinib; oral
131.2
71.4
76
6
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
4.4
70.5
275
686
JN4AD
NOMESCO Finland
Body CT examination
3.8
70.1
335
1005
8140/3-C34.2
ICD-O-3
Adenocarcinoma, NOS, of middle lobe, lung
+∞
68.1
65
*
A04AA55
ATC
palonosetron, combinations; systemic
9.1
65.9
144
169
XX3DW
NOMESCO Finland
Time consuming IT work
3.3
65.6
383
1339
GDB21
NOMESCO Finland
Thoracoscopic segmental resection of lung
64.7
64.8
75
12
C34.00
ICD-10 Finland
Malignant tumor of the main bronchus without histology
22.8
64.5
94
43
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
6.3
64.3
181
311
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.3
61.5
249
640
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
6.5
61.3
168
278
3004
Kela drug reimbursment
Osimertinib
+∞
60.7
58
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
6.7
60.3
161
257
C34.02
ICD-10 Finland
Malignant tumor of the main bronchial adenocarcinoma
131.8
60.2
64
5
L01XE13
ATC
[U] afatinib; oral
310.7
59.6
60
*
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
25.3
58.9
83
34
J93.8
ICD-10 Finland
Other pneumothorax
29.2
58.3
79
28
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
18.0
57.1
90
52
R4110
NOMESCO Finland
Physiotherapy
2.3
56.8
711
3843
A04AA02
ATC
granisetron; systemic, transdermal
3.9
56.5
249
690
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.2
56.4
803
4601
1519
Kela drug reimbursment
NA
+∞
55.4
53
*
TGD00
NOMESCO Finland
Needle biopsy of lung
25.2
55.3
78
32
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
30.6
55.3
74
25
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
24.7
52.2
74
31
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
13.5
52.1
92
71
C34.39
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other or unspecified histology
22.8
51.7
75
34
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
50.3
688
3826
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.3
50.2
284
956
ZX050
NOMESCO Finland
Stereotactic radiotherapy
14.8
49.5
84
59
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
49.2
443
2004
GD2CT
NOMESCO Finland
Cytology of the lungs with CT guidance
108.6
49.0
53
5
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
17.9
48.3
76
44
C34.80
ICD-10 Finland
Malignant overall tumor of bronchus and lung without histology
25.0
48.2
68
28
L01EB04
ATC
osimertinib; oral
+∞
48.1
46
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.7
46.8
221
646
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.6
46.8
226
674
341
Kela drug reimbursment
Afatinib and gefitinib
240.0
46.1
47
*
M05BX04
ATC
denosumab; parenteral
4.1
46.1
191
498
ZX120
NOMESCO Finland
Intravenous
2.9
46.0
316
1213
N03AX16
ATC
pregabalin; oral
2.2
45.7
593
3194
J94.8
ICD-10 Finland
Other specified pleural conditions
6.9
45.5
117
177
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
5.4
45.2
142
278
A06AH03
ATC
naloxegol; oral
9.8
45.0
93
99
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
5.8
45.0
133
242
WX892
NOMESCO Finland
Monitored bed care
3.1
43.5
267
951
B01AB10
ATC
tinzaparin; parenteral
3.3
42.6
238
791
TGA30
NOMESCO Finland
Thoracocentesis
10.1
42.0
85
87
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
42.0
561
3044
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.6
41.9
202
600
TGE00
NOMESCO Finland
Needle biopsy of mediastinum
21.6
41.5
61
29
WX250
NOMESCO Finland
Intercostal blockade
40.2
40.7
51
13
XG410
NOMESCO Finland
Flow-volume spirometry
4.0
40.4
173
464
GD2AT
NOMESCO Finland
Cytology of the lungs with ultrasound guidance
33.2
39.9
52
16
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
7.0
39.0
99
147
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
7.5
38.4
93
129
L01XE02
ATC
[U] gefitinib; oral
+∞
37.6
36
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
24.6
37.6
53
22
J01MA14
ATC
moxifloxacin; systemic
2.7
37.3
277
1106
N02AX02
ATC
tramadol; systemic, rectal
1.8
37.1
1004
7011
H02AB06
ATC
prednisolone; systemic
1.8
36.9
1074
7680
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
5.9
36.8
106
187
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
20.5
36.2
54
27
C34.2
ICD-10 Finland
Malignant neoplasm: Middle lobe, bronchus or lung
30.6
36.1
48
16
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
25.5
35.9
50
20
JN4CD
NOMESCO Finland
Very extensive body CT
3.8
35.6
160
447
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.3
35.4
188
601
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.3
35.1
188
605
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.3
34.8
187
603
1623C
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Upper lobe, bronchus or lung[NEOPL MAL LOB SUPER PULMONIS,ADENOCARCINOMA]
342.3
34.0
34
*
C34.20
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung without histology
36.5
33.8
43
12
J01MA12
ATC
levofloxacin; systemic
2.0
33.3
522
2979
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
17.6
31.9
50
29
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
13.7
31.8
55
41
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
6.0
31.7
90
156
N02AA01
ATC
morphine; systemic, rectal
6.0
31.7
90
156
C79.31
ICD-10 Finland
Secondary malignant tumor of the cerebellum
27.4
31.5
43
16
ZX090
NOMESCO Finland
Other technic of radiotherapy
4.1
31.5
128
327
N07BA03
ATC
varenicline; oral
4.3
31.2
120
291
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
31.1
463
2578
C34
ICD-10 Finland
Malignant neoplasm of bronchus and lung
33.1
30.0
39
12
Z2446
NOMESCO Finland
Social worker
3.1
29.9
174
591
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
15.3
29.1
48
32
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
13.9
28.6
49
36
J93.9
ICD-10 Finland
Pneumothorax, unspecified
19.0
28.3
43
23
1504
Kela drug reimbursment
Alectinib
+∞
28.2
27
*
3001
Kela drug reimbursment
Alectinib
+∞
28.2
27
*
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.2
28.0
155
510
GEA00
NOMESCO Finland
Mediastinoscopy
22.6
27.9
40
18
A04AD12
ATC
aprepitant; systemic
5.8
27.7
80
142
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
9.3
27.7
58
64
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.9
27.6
92
193
R03AC02
ATC
salbutamol; inhalant
1.7
27.2
1018
7574
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
5.4
27.2
83
158
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.1
27.0
109
277
A79
ICPC
Malignancy NOS
5.9
26.8
76
132
GDC10
NOMESCO Finland
Bilobectomy of lung
141.7
26.7
28
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
7.9
26.5
61
79
A98
ICPC
Health maint/preventive medicine
0.6
26.4
1478
17020
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.7
26.3
186
717
169
Kela drug reimbursment
Crizotinib
+∞
26.1
25
*
L01XE35
ATC
[U] osimertinib; oral
+∞
26.1
25
*
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
6.9
25.4
64
95
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
8.9
25.3
54
62
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
7.3
25.1
61
86
A02BC02
ATC
pantoprazole; systemic
1.6
24.7
1368
11160
B03BA03
ATC
hydroxocobalamin; parenteral
2.5
24.5
202
852
L01ED03
ATC
alectinib; oral
+∞
24.0
23
*
L01EB03
ATC
afatinib; oral
+∞
24.0
23
*
R06.0
ICD-10 Finland
Dyspnoea
1.7
23.6
593
3900
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
7.3
23.6
57
80
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
6.3
23.1
62
101
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
16.6
22.7
36
22
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.6
22.6
178
732
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
22.5
275
1398
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
6.6
22.1
57
88
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.6
21.9
171
699
L01XE16
ATC
[U] crizotinib; oral
+∞
21.9
21
*
R04.2
ICD-10 Finland
Haemoptysis
3.0
21.9
128
438
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
21.6
373
2166
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
21.3
823
6045
1CD01
NOMESCO Finland
NA
28.3
20.9
28
10
8140/3-C34.0
ICD-O-3
Adenocarcinoma, NOS, of main bronchus
+∞
20.9
20
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
5.7
20.4
59
106
TGC00
NOMESCO Finland
Bronchial lavation
3.5
20.0
95
279
L01XE36
ATC
[U] alectinib; oral
+∞
19.8
19
*
Z3231
NOMESCO Finland
Registered nurse
1.6
19.6
603
4155
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
7.3
19.6
47
66
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
19.4
903
6887
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
6.7
19.4
49
74
B01AB04
ATC
dalteparin; parenteral
2.6
19.3
144
572
C34.0
ICD-10 Finland
Malignant neoplasm: Main bronchus
11.8
19.3
35
30
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
19.2
290
1596
GDC11
NOMESCO Finland
Thoracoscopic bilobectomy of lung
191.5
18.6
19
*
D38.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Respiratory organ, unspecified
16.3
18.3
29
18
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
10.4
18.1
35
34
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
17.9
780
5829
PJD99
NOMESCO Finland
Excision of other lymph nodes
26.9
17.8
24
9
5826
FHL
Lobectomy or bilobectomy
15.7
17.5
28
18
GDD00
NOMESCO Finland
Pneumonectomy
29.0
17.4
23
8
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
5.3
17.1
52
100
C34.89
ICD-10 Finland
Malignant overall tumor of the bronchus and lung other or unspecified histology
16.1
17.0
27
17
Z3226
NOMESCO Finland
Physiotherapist
1.7
17.0
400
2549
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.8
17.0
112
415
Z2221
NOMESCO Finland
Medical doctor
1.6
16.9
554
3860
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
16.4
16.5
26
16
C79.7
ICD-10 Finland
Secondary malignant neoplasm of adrenal gland
40.4
16.3
20
5
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
3.3
16.0
81
251
GAC00
NOMESCO Finland
Biopsy of pleura
9.0
15.9
33
37
ZXA00
NOMESCO Finland
Right side
1.5
15.2
601
4353
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
15.1
344
2163
C34.13
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary bronchoalveolar carcinoma
45.3
15.1
18
*
WW200
SPAT
NA
0.3
14.9
25
913
J86.9
ICD-10 Finland
Pyothorax without fistula
5.9
14.8
41
71
WX402
NOMESCO Finland
General anaesthesia
1.8
14.8
300
1821
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
6.9
14.7
36
53
WX330
NOMESCO Finland
Paravertebral ansthesia
+∞
14.6
14
*
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
8.5
14.5
31
37
C34.29
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung other or unspecified histology
22.4
14.2
20
9
ZX070
NOMESCO Finland
Intensity modified radiotherapy
3.2
13.9
72
229
L03AA13
ATC
pegfilgrastim; parenteral
2.7
13.8
91
340
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.3
13.7
23
840
N06DX01
ATC
memantine; oral
0.3
13.6
29
941
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.6
13.6
322
4680
363
Kela drug reimbursment
Crizotinib
+∞
13.5
13
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
3.8
13.5
56
149
C79.3
ICD-10 Finland
Secondary malignant neoplasm of brain and cerebral meninges
34.2
13.5
17
5
C34.01
ICD-10 Finland
Malignant tumor of the main bronchial epidermoid carcinoma
12.9
13.4
23
18
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
12.9
13.4
23
18
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
9.7
13.2
26
27
C78.1
ICD-10 Finland
Secondary malignant neoplasm of mediastinum
19.1
12.9
19
10
ZX080
NOMESCO Finland
Image guided radiotherapy
3.5
12.9
60
176
ZXE00
NOMESCO Finland
One hour or less
1.4
12.9
764
5978
SPAT1109
SPAT
Analgesia with portable analgesic pump
7.0
12.9
31
45
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.9
12.8
52
136
R85
ICPC
Malignant neopl respiratory other
14.1
12.7
21
15
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
12.6
374
2517
8140/3-C34.8
ICD-O-3
Adenocarcinoma, NOS, of overlapping lesion of lung
+∞
12.5
12
*
1625C
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Lower lobe, bronchus or lung[NEOPL MAL LOBI INFERIORIS PULMONIS,ADENOCARCINOMA]
+∞
12.5
12
*
J43.9
ICD-10 Finland
Emphysema, unspecified
3.4
12.5
60
181
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
0.6
12.4
312
4496
TXQ05
NOMESCO Finland
Puncture of skin, site unspecified
130.7
12.4
13
*
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
5.6
12.4
35
63
A06AD11
ATC
lactulose; oral
1.6
12.3
358
2397
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
12.2
302
1937
N05CF01
ATC
zopiclone; oral
1.4
11.9
685
5309
C34.09
ICD-10 Finland
Malignant tumor of the main bronchus other or unspecified histology
13.4
11.9
20
15
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.2
11.9
119
554
M17.1
ICD-10 Finland
Other primary gonarthrosis
0.6
11.8
205
3206
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
0.7
11.7
581
7397
R2110
NOMESCO Finland
Giving the first information
2.2
11.6
121
572
F03
ICD-10 Finland
Unspecified dementia
0.2
11.6
14
615
325
Kela drug reimbursment
Erlotinib
65.3
11.6
13
*
SPAT1053
SPAT
Memory test
0.6
11.5
174
2810
SFA10
NOMESCO Finland
Fillning on one surface of tooth
0.7
11.5
551
7063
L01EB01
ATC
gefitinib; oral (epidermal growth factor receptor (egfr) tyrosine kinase inhibitors)
120.6
11.4
12
*
C38.4
ICD-10 Finland
Malignant neoplasm: Pleura
120.6
11.4
12
*
GD2FN
NOMESCO Finland
Lung ventilation distribution isotope examination (radiospirometry)
120.6
11.4
12
*
RS221
NOMESCO Finland
NA
4.1
11.4
43
106
1BC05
NOMESCO Finland
NA
35.2
11.3
14
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
11.2
123
597
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
1.8
11.1
181
1021
GDA21
NOMESCO Finland
Thoracoscopic excision of lesion of lung
25.1
11.1
15
6
C34.33
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung bronchoalveolar carcinoma
25.1
11.1
15
6
C34.91
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary epidermoid carcinoma
13.9
11.0
18
13
N06DA02
ATC
donepezil; oral
0.3
11.0
26
801
R50.9
ICD-10 Finland
Fever, unspecified
1.6
10.8
272
1750
WW500
NOMESCO Finland
Blood transfusion
2.3
10.8
100
449
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
10.8
374
2607
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
9.6
10.7
21
22
GA2AT
NOMESCO Finland
Pleural biopsy with ultrasound guidance
28.1
10.7
14
5
D38.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pleura
17.9
10.7
16
9
C79.39
ICD-10 Finland
Secondary malignant tumor of the meninges, ventricle or other part of the brain
17.9
10.7
16
9
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
4.8
10.7
34
71
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
7.0
10.6
25
36
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
2.4
10.5
90
389
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
3.7
10.5
44
120
SAA02
NOMESCO Finland
Basic examination of mouth
0.7
10.4
696
8508
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
10.3
389
2756
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
8.8
10.3
21
24
JN6AD
NOMESCO Finland
CT of torso and neck
4.0
10.2
39
98
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
0.7
10.2
441
5778
C34.21
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung epidermoid carcinoma
13.2
10.1
17
13
R52.0
ICD-10 Finland
Acute pain
2.8
10.1
63
226
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.3
10.1
96
437
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
10.0
140
750
GA3AT
NOMESCO Finland
Pleural cytology with ultrasound guidance
7.3
10.0
23
32
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.3
10.0
18
631
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.3
9.9
89
396
C80.92
ICD-10 Finland
Malignant tumor without specified localization adenocarcinoma
12.2
9.8
17
14
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
2.7
9.8
66
251
SAA01
NOMESCO Finland
Simple examination of mouth
0.7
9.7
831
9839
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
13.4
9.7
16
12
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.2
9.6
90
410
GAA31
NOMESCO Finland
Thoracoscopy
8.4
9.5
20
24
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
0.4
9.3
49
1088
GDB10
NOMESCO Finland
Wedge resection of lung
9.5
9.3
18
19
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
3.6
9.2
40
113
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.6
9.2
248
1625
WW200
NOMESCO Finland
Immunization
2.8
9.1
57
206
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
9.1
236
1532
P20
ICPC
Memory disturbance
0.6
9.0
119
1997
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
9.0
85
387
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
2.6
8.9
62
242
WF099
NOMESCO Finland
Other radiotherapy
5.2
8.9
26
50
OAB42
SPAT
NA
0.2
8.9
6
375
ZXD05
NOMESCO Finland
Urgent procedure
1.4
8.8
573
4489
N06DA03
ATC
rivastigmine; oral, transdermal
0.3
8.8
13
505
C34.15
ICD-10 Finland
Malignant tumor of the anterior, bronchial or lung other non-microcellular carcinoma
10.7
8.8
16
15
N03AX14
ATC
levetiracetam; systemic
2.7
8.7
59
225
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
8.6
642
5144
R03BB01
ATC
ipratropium bromide; inhalant
1.9
8.6
118
627
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
0.2
8.6
12
480
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
0.7
8.5
326
4382
K02.1
ICD-10 Finland
Caries of dentine
0.7
8.5
600
7341
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
0.2
8.5
11
460
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
0.7
8.5
414
5349
C34.35
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other non-microcellular carcinoma
20.1
8.5
12
6
WX600
NOMESCO Finland
Single shot through catheter
4.1
8.5
31
76
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.4
8.4
24
45
C34.23
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung bronchoalveolar carcinoma
90.4
8.4
9
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.0
8.4
46
156
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
8.3
612
4889
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
3.7
8.1
34
94
GCA32
NOMESCO Finland
Endoscopic insertion of stent into bronch
22.1
8.0
11
5
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
2.7
7.9
52
197
R95
ICPC
Chron obstructive pulmonary disease
2.2
7.9
78
362
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.4
7.8
27
705
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
5.4
7.8
22
41
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.7
7.8
50
187
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
7.0
7.8
18
26
C39.9
ICD-10 Finland
Malignant neoplasm: Ill-defined sites within the respiratory system
45.1
7.7
9
*
205
Kela drug reimbursment
Chronic hypertension
0.7
7.7
449
5660
N05BA04
ATC
oxazepam; oral
1.4
7.6
430
3282
XX9XW
NOMESCO Finland
NA
5.2
7.5
22
43
GEA20
NOMESCO Finland
Mediastinoscopy with excision of lesion
10.1
7.5
14
14
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.6
7.5
173
2559
Z72.0
ICD-10 Finland
Tobacco use
2.8
7.5
46
169
GA2CT
NOMESCO Finland
Pleural biopsy with CT guidance
80.3
7.4
8
*
G20
ICD-10 Finland
Parkinson disease
0.3
7.3
11
426
1629C
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Bronchus and lung, unspecified[NEOPL MAL PULMONIS LOCO ALIO/NUD,ADENOCARCINOMA]
+∞
7.3
7
*
L01ED01
ATC
crizotinib; oral
+∞
7.3
7
*
1XC18
NOMESCO Finland
NA
+∞
7.3
7
*
QBC00
NOMESCO Finland
Removal of foreign body from skin of trunk or subcutaneous tissue
10.9
7.3
13
12
J94.9
ICD-10 Finland
Pleural condition, unspecified
5.2
7.2
21
41
SDA01
NOMESCO Finland
Simple parodonthologic therapy
0.7
7.2
188
2713
ZXE30
NOMESCO Finland
More than five and less than seven hours
1.9
7.2
103
559
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.5
7.2
55
1071
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.5
7.2
51
204
S27.0
ICD-10 Finland
Traumatic pneumothorax
4.2
7.1
25
60
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
3.1
7.1
36
117
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
7.0
106
586
ZXA05
NOMESCO Finland
Left side
1.3
7.0
510
4046
L03AA02
ATC
filgrastim; parenteral
2.3
7.0
60
264
JN4DD
NOMESCO Finland
Scout CT scan of torso
10.0
7.0
13
13
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
3.8
7.0
27
71
1CD02
NOMESCO Finland
NA
4.5
6.9
23
52
L03AA14
ATC
lipegfilgrastim; parenteral
2.9
6.9
40
140
R02
ICPC
Shortness of breath/dyspnoea
1.5
6.9
223
1525
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
0.2
6.9
9
373
SPAT1312
SPAT
General health counselling
0.7
6.9
338
4380
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
2.7
6.8
44
165
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
2.3
6.8
61
275
1623X
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Upper lobe, bronchus or lung[NEOPL MAL LOB SUPER PULMONIS,EI HIST/SYTOL DG]
11.0
6.8
12
11
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.7
6.8
44
166
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
4.5
6.8
22
49
C34.14
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary macrocellular anaplastic carcinoma
40.2
6.8
8
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
0.6
6.7
123
1910
GWE00
NOMESCO Finland
Reoperation for deep haemorrhage in thoracic surgery
16.7
6.7
10
6
1240
FHL
Bronchoscopy
3.0
6.7
35
116
ZYC01
SPAT
NA
0.3
6.7
12
420
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
4.7
6.7
21
45
L57.0
ICD-10 Finland
Actinic keratosis
0.6
6.7
96
1574
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
4.0
6.6
24
60
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
6.6
200
1349
Z01.2
ICD-10 Finland
Dental examination
0.7
6.5
395
4978
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
6.5
207
1407
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
4.8
6.5
20
42
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
0.6
6.5
70
1236
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
0.0
6.5
*
161
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.0
6.5
79
405
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
3.4
6.4
28
82
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
3.0
6.4
34
115
SPAT1249
SPAT
Treatment-related counselling outside office
0.8
6.4
481
5885
B01AF01
ATC
rivaroxaban; oral
0.6
6.4
117
1814
N40
ICD-10 Finland
Hyperplasia of prostate
0.7
6.4
384
4840
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
8.2
6.3
13
16
UGB02
NOMESCO Finland
Tracheoscopy
8.2
6.3
13
16
L15
ICPC
Knee symptom/complaint
0.7
6.3
194
2720
J01AA02
ATC
doxycycline; systemic
1.3
6.3
1482
13650
C79.2
ICD-10 Finland
Secondary malignant neoplasm of skin
9.3
6.3
12
13
3017
Kela drug reimbursment
Brigatinib
+∞
6.2
6
*
1628C
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Other parts of bronchus or lung[NEOPL MAL PULMONIS LOCO MULTIPLICI,ADENOCARCINOMA]
+∞
6.2
6
*
GEB40
NOMESCO Finland
Mediastinotomy and extended excision of lesion
+∞
6.2
6
*
XG466
NOMESCO Finland
Sleep oxymetry
2.1
6.2
68
333
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
1.8
6.1
98
552
A04AA03
ATC
tropisetron; systemic
5.7
6.1
16
28
J85.2
ICD-10 Finland
Abscess of lung without pneumonia
7.7
6.1
13
17
HA1AA
NOMESCO Finland
X-ray mammography
1.7
6.1
114
676
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.1
302
2246
C10AA07
ATC
rosuvastatin; oral
0.7
6.1
287
3754
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
3.3
6.1
28
86
A02BC01
ATC
omeprazole; systemic
1.3
6.0
549
4491

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_NSCLC_ADENO – Non-small cell lung cancer, adenocarcinoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).