Sleep disorders, other/unspecified

F5_SLEEP_NOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1311

4. Check minimum number of events

None

1311

5. Include endpoints

None

1311

6. Filter based on genotype QC (FinnGen only)

1311

Control definitions (FinnGen only)

Control exclude
F5_SLEEP

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11736 5917 5770
Only index persons 10393 5350 5043
Unadjusted period prevalence (%)
Whole population 0.16 0.17 0.16
Only index persons 0.19 0.20 0.19
Median age at first event (years)
Whole population 26.58 31.11 21.85
Only index persons 29.83 33.99 25.42

-FinnGen-

Key figures

All Female Male
Number of individuals 1311 875 436
Unadjusted period prevalence (%) 0.26 0.30 0.19
Median age at first event (years) 42.82 41.76 44.95

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1134
Matched controls
11337
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
1479.6
323.0
998
56
N06AX11
ATC
mirtazapine; oral
8.6
237.4
755
2139
N05AH04
ATC
quetiapine; oral
9.1
220.6
576
1157
F51.0
ICD-10 Finland
Nonorganic insomnia
10.0
207.7
485
790
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
23.1
187.6
279
158
F51.8
ICD-10 Finland
Other nonorganic sleep disorders
142.6
162.3
170
14
N05CF01
ATC
zopiclone; oral
4.9
123.8
539
1759
N05BA04
ATC
oxazepam; oral
4.7
110.2
479
1515
N05CF02
ATC
zolpidem; oral
4.8
90.2
363
1021
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.6
82.9
338
952
IAB13
NOMESCO Finland
Psychiatric sleep disorder consultation
+∞
81.2
77
*
P06
ICPC
Sleep disturbance
5.5
78.8
263
592
N06AX16
ATC
venlafaxine; oral
4.3
74.3
325
966
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
4.8
74.1
286
750
N05AA02
ATC
levomepromazine; systemic
11.4
70.9
138
136
N05AH03
ATC
olanzapine; systemic
6.6
67.8
188
331
N06AX05
ATC
trazodone; oral
14.0
67.7
119
94
N06AB10
ATC
escitalopram; oral
3.4
66.9
410
1601
N06AB04
ATC
citalopram; systemic
3.5
60.9
357
1327
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.1
58.8
263
778
N05BA01
ATC
diazepam; systemic, rectal
4.2
57.7
247
700
N06AB06
ATC
sertraline; oral
4.2
57.3
250
721
N05CD07
ATC
temazepam; oral
5.4
56.8
187
403
N06AX12
ATC
bupropion; oral
5.1
55.5
192
437
N06AX03
ATC
mianserin; oral
7.8
51.9
125
177
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
6.8
51.1
136
223
N06AA06
ATC
trimipramine; systemic
11.7
50.1
95
88
N06AA12
ATC
doxepin; systemic
7.7
49.7
121
174
C07AA05
ATC
propranolol; systemic
3.1
48.9
334
1355
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
3.8
48.9
236
735
N03AX16
ATC
pregabalin; oral
3.1
48.8
333
1349
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
8.1
48.5
114
155
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
5.6
48.3
150
299
N06AX21
ATC
duloxetine; oral
4.1
47.5
209
599
G47.9
ICD-10 Finland
Sleep disorder, unspecified
10.2
47.1
96
102
N03AE01
ATC
clonazepam; systemic
6.3
47.0
132
232
N06AB03
ATC
fluoxetine; oral
3.7
46.9
233
741
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.4
46.6
184
475
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.9
45.5
211
632
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
5.2
45.4
152
330
IEY18
NOMESCO Finland
Psychiatric sleep coaching, individual
443.9
43.5
43
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.5
42.2
162
405
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
8.5
42.0
95
121
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
6.9
41.3
107
168
N03AG01
ATC
valproic acid; systemic, rectal
5.1
41.0
137
296
F51
ICD-10 Finland
Nonorganic sleep disorders
6.7
39.7
106
173
N05AX08
ATC
risperidone; systemic
4.6
39.1
145
349
G47.3
ICD-10 Finland
Sleep apnoea
2.9
36.7
266
1091
N06CA01
ATC
amitriptyline and psycholeptics; systemic
4.0
36.1
157
439
N03AX09
ATC
lamotrigine; oral
4.7
34.4
125
294
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
8.7
34.2
75
91
N05AF03
ATC
chlorprothixene; systemic
8.0
33.5
78
104
F41.1
ICD-10 Finland
Generalized anxiety disorder
4.2
33.1
134
350
R53
ICD-10 Finland
Malaise and fatigue
2.6
33.0
286
1298
N06AX22
ATC
agomelatine; oral
7.2
32.8
82
122
N04BC05
ATC
pramipexole; oral
5.0
32.4
110
240
N06AA09
ATC
amitriptyline; systemic
3.9
32.1
142
402
N03AX12
ATC
gabapentin; oral
2.9
31.1
211
822
P29
ICPC
Psychological sympt/compl other
3.7
31.0
147
441
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.0
29.6
100
217
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
7.1
28.8
72
107
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
5.7
28.8
86
162
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
28.8
476
2913
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.1
28.7
119
317
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
7.2
28.4
70
102
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.4
28.4
107
260
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
7.4
28.3
69
99
A02BC02
ATC
pantoprazole; systemic
2.0
28.3
684
4870
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
5.9
28.0
80
143
N05BA12
ATC
alprazolam; oral
3.3
27.3
152
514
F32.1
ICD-10 Finland
Moderate depressive episode
3.6
27.0
128
382
N06AX26
ATC
vortioxetine; oral
3.7
26.8
125
368
G44.2
ICD-10 Finland
Tension-type headache
2.6
26.0
211
909
R51.80
ICD-10 Finland
Headache
2.4
25.2
239
1120
P01
ICPC
Feeling anxious/nervous/tense
2.5
25.2
236
1098
Z71.8
ICD-10 Finland
Other specified counselling
2.2
25.2
336
1852
M79.6
ICD-10 Finland
Pain in limb
2.0
24.8
416
2518
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
7.0
24.4
61
91
N05AX12
ATC
aripiprazole; systemic
4.3
24.0
93
232
G47.0
ICD-10 Finland
Disorders of initiating and maintaining sleep [insomnias]
8.1
23.4
53
68
A01
ICPC
Pain general/multiple sites
3.5
23.4
114
348
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
4.2
23.2
92
235
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
7.0
22.8
57
85
IGY02
NOMESCO Finland
Psychiatric monitoring contact
5.7
22.8
67
124
N02AX02
ATC
tramadol; systemic, rectal
2.0
22.7
427
2681
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
7.5
22.7
54
75
F60.9
ICD-10 Finland
Personality disorder, unspecified
8.2
22.7
51
65
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.9
22.6
97
266
P74
ICPC
Anxiety disorder/anxiety state
3.9
22.4
97
268
N05BA06
ATC
lorazepam; systemic, sublingual
5.0
22.3
73
153
P03
ICPC
Feeling depressed
2.5
22.1
187
818
A06AC01
ATC
ispaghula (psylla seeds); oral
2.2
22.0
248
1257
F43.1
ICD-10 Finland
Post-traumatic stress disorder
5.1
21.2
68
140
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
5.2
20.9
66
133
N06AB08
ATC
fluvoxamine; oral
5.8
20.8
60
109
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
20.8
280
1532
G47.2
ICD-10 Finland
Disorders of the sleep-wake schedule
78.3
20.7
23
*
N06AB05
ATC
paroxetine; oral
3.3
20.5
108
350
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.0
20.5
126
455
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.0
20.3
66
138
P76
ICPC
Depressive disorder
2.9
19.9
126
461
N05AB03
ATC
perphenazine; systemic, rectal
4.9
19.8
66
142
L17
ICPC
Foot/toe symptom/complaint
2.0
19.5
290
1644
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
9.4
19.5
40
44
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
8.0
19.4
44
57
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
5.7
19.4
56
102
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.1
19.3
78
203
IGY99
NOMESCO Finland
Other psychiatric treatment contact
5.1
19.2
61
124
F90.0
ICD-10 Finland
Disturbance of activity and attention
3.8
19.1
84
236
R4110
NOMESCO Finland
Physiotherapy
2.0
18.9
294
1697
F34.1
ICD-10 Finland
Dysthymia
3.9
18.8
79
213
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.0
18.8
283
1610
M54.5
ICD-10 Finland
Low back pain
1.9
18.7
388
2484
A02BC05
ATC
esomeprazole; systemic
1.8
18.6
408
2659
F10.25
ICD-10 Finland
Alcohol dependence continuous use
7.7
18.5
43
58
F32
ICD-10 Finland
Depressive episode
3.1
18.5
105
359
N06BA04
ATC
methylphenidate; oral
4.2
18.3
71
178
N06AG02
ATC
moclobemide; oral
4.4
18.3
67
159
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.9
18.1
113
411
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
4.1
18.1
71
180
A02BC01
ATC
omeprazole; systemic
2.0
18.0
274
1563
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.4
17.9
91
287
F51.2
ICD-10 Finland
Nonorganic disorder of the sleep-wake schedule
23.2
17.8
25
11
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
6.1
17.7
48
81
C07AB07
ATC
bisoprolol; oral
1.8
17.5
363
2308
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
5.6
17.5
51
94
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
6.6
17.5
45
71
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.2
17.4
202
1026
N05BE01
ATC
buspirone; oral
4.6
17.3
60
135
N05AN01
ATC
lithium; oral
4.9
17.2
57
122
IBA03
NOMESCO Finland
Psychotherapy evaluation
8.2
17.1
38
48
N07BB01
ATC
disulfiram; oral
3.7
17.0
76
216
R5140
NOMESCO Finland
Monitoring the use of the aid
2.7
16.8
117
456
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
6.8
16.7
42
64
F61.0
ICD-10 Finland
Mixed personality disorders
5.3
16.5
50
97
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
16.5
163
768
L01
ICPC
Neck symptom/complaint
2.2
16.5
185
925
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
5.7
16.4
47
85
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
7.3
16.4
39
55
A04
ICPC
Weakness/tiredness general
2.2
16.2
181
900
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
5.5
16.2
48
91
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
16.0
206
1090
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.7
16.0
113
444
XA800
NOMESCO Finland
Neuropsychological investigation
3.6
16.0
73
212
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
15.8
223
1226
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
5.3
15.7
48
94
L03
ICPC
Low back symptom/complaint
1.9
15.7
284
1713
F99
ICD-10 Finland
Mental disorder, not otherwise specified
4.9
15.6
51
108
AA1AD
NOMESCO Finland
CT of head and brain
2.1
15.6
203
1080
M25.5
ICD-10 Finland
Pain in joint
1.8
15.5
325
2057
M03BX02
ATC
tizanidine; oral
1.7
15.4
662
5178
N03AX11
ATC
topiramate; oral
4.7
15.3
52
115
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
15.2
474
3385
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
5.1
15.0
47
95
F39
ICD-10 Finland
Unspecified mood [affective] disorder
4.7
15.0
51
113
R06.0
ICD-10 Finland
Dyspnoea
1.9
14.9
239
1375
P16
ICPC
Acute alcohol abuse
6.8
14.9
37
56
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
13.4
14.7
25
19
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.6
14.7
109
442
P99
ICPC
Psychological disorders other
3.9
14.6
60
159
F51.3
ICD-10 Finland
Sleepwalking [somnambulism]
+∞
14.6
14
*
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
14.4
221
1250
SPAT1240
SPAT
Therapeutic discussion
2.1
14.1
177
925
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
9.5
14.0
28
30
N05AB01
ATC
dixyrazine; systemic
12.9
13.9
24
19
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
13.9
241
1422
F31.8
ICD-10 Finland
Other bipolar affective disorders
4.9
13.9
45
95
N05BA02
ATC
chlordiazepoxide; systemic
5.9
13.8
38
66
R00.2
ICD-10 Finland
Palpitations
2.6
13.8
103
418
N05CD02
ATC
nitrazepam; oral
9.8
13.7
27
28
A06AD11
ATC
lactulose; oral
2.4
13.6
119
524
D11
ICPC
Diarrhoea
2.1
13.6
163
834
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
13.6
188
1021
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
13.4
820
6921
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
8.2
13.3
29
36
WX110
NOMESCO Finland
Local anesthesy
1.6
13.3
799
6702
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
5.3
13.3
40
78
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
5.3
13.3
40
78
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
10.2
13.0
25
25
N05AD01
ATC
haloperidol; systemic
4.8
13.0
43
93
F60.5
ICD-10 Finland
Anankastic personality disorder
6.4
12.8
33
53
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
12.8
277
1757
M79.1
ICD-10 Finland
Myalgia
2.1
12.7
159
831
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
12.7
102
431
F13.29
ICD-10 Finland
Addiction caused by sedative and hypnotic UNS
15.6
12.6
20
13
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
6.0
12.6
34
58
K59.0
ICD-10 Finland
Constipation
3.2
12.4
66
217
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
12.4
192
1089
D01
ICPC
Abdominal pain/cramps general
2.0
12.3
158
830
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.9
12.3
39
81
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
12.2
400
2853
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
7.1
12.1
29
42
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.1
12.1
148
763
R05
ICPC
Cough
1.8
12.0
260
1644
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
12.0
364
2537
N05AF01
ATC
flupentixol; systemic
7.3
12.0
28
39
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
10.2
12.0
23
23
N05AA01
ATC
chlorpromazine; systemic, rectal
6.9
12.0
29
43
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.2
11.8
62
202
P15
ICPC
Chronic alcohol abuse
3.9
11.8
47
123
F41.3
ICD-10 Finland
Other mixed anxiety disorders
5.1
11.8
36
72
R74
ICPC
Upper respiratory infection acute
1.6
11.7
404
2908
D12
ICPC
Constipation
4.2
11.7
44
109
R33
ICD-10 Finland
Retention of urine
3.4
11.7
57
176
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.1
11.7
133
666
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
7.8
11.7
26
34
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.6
11.7
429
3139
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
4.9
11.5
37
78
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
6.4
11.4
29
46
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
11.4
597
4745
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
12.0
11.3
20
17
AA400
NOMESCO Finland
Electroconvulsive therapy
8.4
11.3
24
29
F22.0
ICD-10 Finland
Delusional disorder
7.4
11.3
26
36
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
11.2
96
420
F20.9
ICD-10 Finland
Schizophrenia, unspecified
4.5
11.1
38
86
R42
ICD-10 Finland
Dizziness and giddiness
1.8
11.0
193
1138
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
11.0
567
4476
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
7.5
11.0
25
34
F40.1
ICD-10 Finland
Social phobias
3.4
10.9
52
158
H02AB06
ATC
prednisolone; systemic
1.5
10.7
442
3309
A29
ICPC
General symptom/complaint other
2.2
10.7
111
534
M01AE02
ATC
naproxen; oral, rectal
1.5
10.7
630
5116
G47.8
ICD-10 Finland
Other sleep disorders
8.1
10.6
23
29
F21
ICD-10 Finland
Schizotypal disorder
11.3
10.6
19
17
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
10.6
114
557
L08
ICPC
Shoulder symptom/complaint
1.8
10.5
181
1060
S21
ICPC
Skin texture symptom/complaint
2.1
10.5
127
651
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
10.4
273
1818
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
7.8
10.4
23
30
F51.5
ICD-10 Finland
Nightmares
32.8
10.3
13
*
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
6.1
10.3
27
45
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
5.6
10.3
29
53
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
10.3
70
271
R03AC02
ATC
salbutamol; inhalant
1.5
10.3
570
4546
N17
ICPC
Vertigo/dizziness
2.2
10.3
112
548
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
10.7
10.3
19
18
WX002
NOMESCO Finland
Sedation and analgesia
1.8
10.3
175
1019
SPAT1307
SPAT
Psychosocial counselling and guidance
2.1
10.3
117
587
R06.5
ICD-10 Finland
Mouth breathing
2.3
10.2
100
466
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
10.2
175
1024
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
10.2
194
1175
A02BC03
ATC
lansoprazole; oral
1.7
10.2
240
1550
N02BE01
ATC
paracetamol; systemic, rectal
1.6
10.1
887
7841
WX780
NOMESCO Finland
Remote monitoring CPAP
3.4
10.1
48
146
G43.9
ICD-10 Finland
Migraine, unspecified
2.3
10.1
95
438
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
14.7
10.0
16
11
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
10.0
74
300
F51.4
ICD-10 Finland
Sleep terrors [night terrors]
40.4
10.0
12
*
F32.8
ICD-10 Finland
Other depressive episodes
4.4
9.9
35
82
S29
ICPC
Skin symptom/complaint other
1.8
9.9
169
985
R02
ICPC
Shortness of breath/dyspnoea
2.0
9.9
123
639
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
9.9
136
733
S06.0
ICD-10 Finland
Concussion
2.0
9.9
122
630
R52.2
ICD-10 Finland
Other chronic pain
3.5
9.9
45
133
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
9.8
329
2330
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.7
9.8
66
254
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
9.8
537
4260
N05AE04
ATC
ziprasidone; systemic
7.9
9.6
21
27
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
9.6
339
2429
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
5.5
9.5
27
50
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.8
9.5
190
1163
N01
ICPC
Headache
1.8
9.5
182
1100
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
9.5
174
1040
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.9
9.5
37
96
WX723
NOMESCO Finland
CPAP therapy
3.5
9.4
43
127
R5599
NOMESCO Finland
Other rehabilitation service
3.7
9.4
40
112
K30
ICD-10 Finland
Functional dyspepsia
2.1
9.4
108
543
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
9.4
138
765
R52.9
ICD-10 Finland
Pain, unspecified
2.2
9.4
94
443
KMAK
NOMESCO Finland
NA
1.5
9.3
575
4652
F41.8
ICD-10 Finland
Other specified anxiety disorders
3.0
9.3
53
182
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
4.1
9.3
35
88
G43.3
ICD-10 Finland
Complicated migraine
4.3
9.2
33
79
UJF32
NOMESCO Finland
Coloscopy
1.7
9.2
203
1282
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
9.2
184
1129
N06AA10
ATC
nortriptyline; systemic
4.6
9.1
30
66
H93.1
ICD-10 Finland
Tinnitus
2.6
9.1
66
266
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
8.4
9.1
19
23
H03AA01
ATC
levothyroxine sodium; systemic
1.7
9.0
222
1447
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
7.5
8.9
20
27
F31
ICD-10 Finland
Bipolar affective disorder
4.7
8.9
29
63
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
8.9
96
469
P01AB01
ATC
metronidazole; oral, rectal
1.5
8.9
396
2983
E66.8
ICD-10 Finland
Other obesity
2.5
8.9
67
276
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.0
8.8
112
584
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
8.7
8.8
18
21
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
9.6
8.8
17
18
TKC20
NOMESCO Finland
Catheterisation of bladder
2.7
8.8
59
226
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.4
8.8
73
317
F50.9
ICD-10 Finland
Eating disorder, unspecified
4.4
8.8
30
69
M79.7
ICD-10 Finland
Fibromyalgia
3.1
8.7
47
158
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.1
8.7
97
481
N06AA04
ATC
clomipramine; systemic
4.9
8.7
27
56
L28
ICPC
Limited function/disability (L)
2.0
8.7
119
639
IEY01
NOMESCO Finland
Psychoeducation, individual
6.7
8.7
21
32
M01AG02
ATC
tolfenamic acid; oral, rectal
1.7
8.7
170
1038
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.1
8.6
92
448
WZA90
NOMESCO Finland
Other doctors statement
1.6
8.6
254
1735
L12
ICPC
Hand/finger symptom/complaint
1.8
8.6
158
943
S18
ICPC
Laceration/cut
1.5
8.6
362
2689
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
8.6
87
415
F13.20
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent
16.4
8.6
13
8
R11
ICD-10 Finland
Nausea and vomiting
2.2
8.5
89
431
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
6.5
8.5
21
33
F43.9
ICD-10 Finland
Reaction to severe stress, unspecified
3.2
8.5
42
133
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
27.7
8.5
11
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
8.5
59
233
L84
ICPC
Back syndrome without radiat pain
2.8
8.5
54
202
F45.8
ICD-10 Finland
Other somatoform disorders
2.1
8.4
97
487
K02.1
ICD-10 Finland
Caries of dentine
1.5
8.4
665
5605
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
6.8
8.4
20
30
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
8.4
457
3582
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
8.4
85
405
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
8.3
133
755
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
4.3
8.3
29
68
M03BC01
ATC
orphenadrine (citrate); systemic
1.6
8.3
253
1743
L29
ICPC
Musculoskeletal sympt/complt other
2.2
8.2
79
366
N06AX17
ATC
milnacipran; oral
5.4
8.2
23
43
R41.0
ICD-10 Finland
Disorientation, unspecified
4.4
8.2
28
65
R35
ICD-10 Finland
Polyuria
2.7
8.1
55
211
J45
ICD-10 Finland
Asthma
2.0
8.1
103
538
F13.24
ICD-10 Finland
Addiction relationship caused by sedative and hypnotic active addiction
11.8
8.1
14
12
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
3.8
8.1
32
85
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
8.0
71
320
R01AD09
ATC
mometasone; nasal
1.4
8.0
488
3902
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
8.0
320
2347
K07.60
ICD-10 Finland
Snapping jaw
2.4
8.0
67
292
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
7.9
256
1786
R12
ICD-10 Finland
Heartburn
2.2
7.9
75
348
C07AB02
ATC
metoprolol; systemic
1.8
7.9
133
774
R61.9
ICD-10 Finland
Hyperhidrosis, unspecified
6.1
7.9
20
33
P27
ICPC
Fear of mental disorder
4.7
7.8
25
54
F10.24
ICD-10 Finland
Alcohol depence active use
4.2
7.8
28
68
X15
ICPC
Vaginal symptom/complaint other
2.5
7.8
57
231
F50.2
ICD-10 Finland
Bulimia nervosa
7.0
7.8
18
26
Z01.7
ICD-10 Finland
Laboratory examination
1.9
7.8
116
646
A02BA04
ATC
nizatidine; systemic
2.5
7.8
60
250
ZXA10
NOMESCO Finland
Bilateral
1.7
7.7
163
1014
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.5
7.7
34
99
A97
ICPC
No disease
1.7
7.7
166
1040
N06BA12
ATC
lisdexamfetamine; oral
7.5
7.7
17
23
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
7.7
124
708
D02
ICPC
Abdominal pain epigastric
2.3
7.6
68
306
K08.80
ICD-10 Finland
Toothache NOS
2.0
7.6
93
479
SPAT1389
SPAT
Visit based on need for special support
2.5
7.6
56
228
N06AX18
ATC
reboxetine; oral
5.0
7.6
23
47
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
7.6
192
1256
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.9
7.6
45
162
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
3.7
7.6
31
85
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
11.9
7.6
13
11
EBA00
NOMESCO Finland
Extraction of tooth
1.5
7.6
350
2638
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
6.2
7.6
19
31
IER01
NOMESCO Finland
Psychoeducation, group
6.2
7.6
19
31
B18.2
ICD-10 Finland
Chronic viral hepatitis C
4.7
7.5
24
52
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
7.5
119
674
Z71
ICD-10 Finland
Persons encountering health services for other counselling and medical advice, not elsewhere classified
2.9
7.5
43
150
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
7.5
203
1354
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
7.5
204
1360
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
7.5
88
449
L15
ICPC
Knee symptom/complaint
1.6
7.4
195
1289
N05AD03
ATC
melperone; systemic
6.0
7.4
19
32
N05AC02
ATC
thioridazine; oral
3.7
7.4
30
82
SXA20
NOMESCO Finland
Local application of medicine to mouth
2.1
7.4
79
388
R60.0
ICD-10 Finland
Localized oedema
2.0
7.3
87
445
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
7.3
593
4967
D09
ICPC
Nausea
2.2
7.3
74
355
L29.9
ICD-10 Finland
Pruritus, unspecified
4.0
7.3
27
68
R21
ICPC
Throat symptom/complaint
1.5
7.2
289
2109
SPAT1260
SPAT
Consultation of another employee
1.7
7.2
169
1080
Z72.1
ICD-10 Finland
Alcohol use
4.7
7.2
23
50
I95.1
ICD-10 Finland
Orthostatic hypotension
4.7
7.2
23
50
A02BA02
ATC
ranitidine; systemic
1.7
7.2
142
865
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.8
7.2
127
749
F33
ICD-10 Finland
Recurrent depressive disorder
3.2
7.2
35
111
G56.2
ICD-10 Finland
Lesion of ulnar nerve
3.0
7.2
38
128
Z50.1
ICD-10 Finland
Other physical therapy
2.6
7.1
50
200
L02
ICPC
Back symptom/complaint
1.9
7.1
109
615
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
5.3
7.1
20
38
L18
ICPC
Muscle pain
2.7
7.1
47
182
AA40B
NOMESCO Finland
NA
12.1
7.1
12
10
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
7.0
72
347
K04
ICPC
Palpitations/awareness of heart
2.5
7.0
52
212
P25
ICPC
Phase of life problem adult
2.4
7.0
56
240
K85
ICPC
Elevated blood pressure
1.9
7.0
97
528
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.3
7.0
59
260
M03BC51
ATC
orphenadrine, combinations; systemic
1.5
7.0
269
1946
J01DB01
ATC
cefalexin; oral
1.5
6.9
876
7920
N89
ICPC
Migraine
2.4
6.9
58
254
J01CA04
ATC
amoxicillin; systemic
1.5
6.9
932
8536
WX290
NOMESCO Finland
Other blockade of nerve
1.4
6.9
536
4437
J01FA06
ATC
roxithromycin; oral
1.4
6.9
374
2901
J01DA01
ATC
[U] cefalexin; systemic
1.4
6.9
635
5416
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.4
6.9
370
2864
M01AH05
ATC
etoricoxib; oral
1.4
6.8
561
4690
N02CC04
ATC
rizatriptan; oral
2.1
6.8
72
351
N04AA02
ATC
biperiden; systemic
3.9
6.8
26
68
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
6.8
106
601
Z73.0
ICD-10 Finland
Burn-out
2.8
6.8
41
151
J01FF01
ATC
clindamycin; systemic
1.5
6.8
247
1765
A99
ICPC
Disease/condition unspecnature/site
2.1
6.7
76
380
R20.2
ICD-10 Finland
Paraesthesia of skin
2.1
6.7
76
380
3007
Kela drug reimbursment
Erenumab and fremanezumab
4.7
6.7
21
45
F60.6
ICD-10 Finland
Anxious [avoidant] personality disorder
7.2
6.7
15
21
G04BD12
ATC
mirabegron; oral
2.2
6.7
62
285
R03AC03
ATC
terbutaline; inhalant
1.7
6.7
144
900
T74.1
ICD-10 Finland
Physical abuse
3.2
6.7
33
106
C09CA06
ATC
candesartan; oral
1.6
6.7
170
1115
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
6.7
186
1248
K59.1
ICD-10 Finland
Functional diarrhoea
2.4
6.7
53
225
F43.8
ICD-10 Finland
Other reactions to severe stress
3.1
6.7
34
112
ZXA00
NOMESCO Finland
Right side
1.5
6.7
211
1461
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
6.6
298
2222
F32.0
ICD-10 Finland
Mild depressive episode
2.8
6.6
40
147
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
6.6
252
1816
Z73.8
ICD-10 Finland
Other problems related to life-management difficulty
5.5
6.6
18
33
N05AH02
ATC
clozapine; systemic
3.3
6.6
31
96
A11
ICPC
Chest pain NOS
2.2
6.6
64
301
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.0
6.6
82
429
IAB11
NOMESCO Finland
Psychiatric mood consultation
12.3
6.6
11
9
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
6.6
99
555
F19.9
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, unspecified mental and behavioural disorder
10.1
6.5
12
12
R51.81
ICD-10 Finland
Facial pain NOS
3.3
6.5
31
97
C03CA01
ATC
furosemide; systemic
1.7
6.5
144
909
A06AC51
ATC
ispaghula, combinations; systemic
2.5
6.5
47
192
G04CA02
ATC
tamsulosin; oral
1.8
6.5
109
635
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.1
6.4
72
360
C07AB12
ATC
nebivolol; oral
3.5
6.4
28
82
R03DC03
ATC
montelukast; oral
1.6
6.4
170
1123
ICC01
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric outpatient clinic
7.4
6.4
14
19
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
6.4
88
476
K92.0
ICD-10 Finland
Haematemesis
3.7
6.4
26
72
P18
ICPC
Medication abuse
6.6
6.3
15
23
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.7
6.3
123
747
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
1.9
6.3
93
514
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.3
426
3422
Z72.8
ICD-10 Finland
Other problems related to lifestyle
6.0
6.3
16
27
Z72.2
ICD-10 Finland
Drug use
6.0
6.3
16
27
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
6.3
79
411
2961C
ICD-9 Finland
Affective psychoses, Manic disorder, recurrent episode[VAKAVA MASENNUSTILA,KESKIVAIKEA]
11.1
6.3
11
10
F30.0
ICD-10 Finland
Hypomania
11.1
6.3
11
10
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.3
6.3
52
228
R4120
NOMESCO Finland
Occupational therapy
2.1
6.3
66
320
F31.2
ICD-10 Finland
Bipolar affective disorder, current episode manic with psychotic symptoms
18.1
6.3
9
5
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.9
6.2
91
505
M54.6
ICD-10 Finland
Pain in thoracic spine
2.0
6.2
79
416
L11
ICPC
Wrist symptom/complaint
1.9
6.2
92
511
H02AB07
ATC
prednisone; oral
1.7
6.2
115
690
F41.00
ICD-10 Finland
Moderate panic disorder
3.2
6.2
30
96
R06AX13
ATC
loratadine; oral
1.6
6.1
173
1165
D10
ICPC
Vomiting
1.9
6.1
88
486
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.0
6.1
32
108
L04
ICPC
Chest symptom/complaint
2.2
6.1
60
283
IFB02
NOMESCO Finland
Transcranial magnetic stimulation (TMS)
12.6
6.1
10
8
F60.1
ICD-10 Finland
Schizoid personality disorder
12.6
6.1
10
8
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
6.1
214
1515
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.1
318
2440
F05.9
ICD-10 Finland
Delirium, unspecified
4.9
6.1
18
37
N06BA09
ATC
atomoxetine; oral
10.1
6.0
11
11
N05AC01
ATC
periciazine; systemic
10.1
6.0
11
11
J02AC01
ATC
fluconazole; systemic
1.4
6.0
413
3320
R51
ICD-10 Finland
Headache
2.0
6.0
69
350

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
434
1854
3.00
70.76
1.6
1.4
21.0
20.6
nmol/l
0.21
395
1613
636
3371
2.72
68.14
2.1
1.8
98.4
96.9
pmol/l
0.37
328
1802
569
2940
2.65
62.93
2.8
3.1
2.4
2.4
mmol/l
0.19
518
2639
154
374
4.53
58.80
2.8
2.8
—
—
—
0
0
700
4204
2.43
53.54
6.5
6.2
1.2
1.2
mmol/l
0.97
592
3559
644
3778
2.38
51.26
6.4
5.7
1.2
1.2
mmol/l
0.12
590
3456
683
4121
2.37
50.82
2.6
2.3
73.8
73.5
nmol/l
0.12
636
3793
190
598
3.55
50.27
3.2
3.0
—
—
—
0
0
298
1233
2.83
49.40
2.7
2.3
2.4
2.4
g/l
0.05
274
1128
479
2503
2.44
49.06
4.5
3.7
7.4
7.4
ph
0.17
82
479
312
1330
2.77
48.79
2.7
2.3
15.2
14.0
umol/l
1.97
289
1222
1101
8415
2.93
46.25
5.4
3.9
14.5
14.5
pmol/l
0.16
1024
7761
273
1126
2.80
45.17
2.8
2.4
25.2
23.6
%
1.01
240
971
999
7430
2.45
41.69
8.0
6.9
73.8
75.6
u/l
0.92
949
6992
994
7431
2.40
40.08
4.4
3.8
9.1
9.7
mm/h
1.09
930
6908
555
3306
2.18
39.71
5.6
6.0
—
—
—
0
0
190
690
3.05
39.35
2.5
2.1
—
—
—
0
0
599
3727
2.12
37.76
4.8
4.7
36.8
36.6
g/l
0.26
554
3477
760
5205
2.09
36.65
3.8
2.8
77.4
86.5
ug/l
1.32
714
4893
205
812
2.81
36.10
2.6
2.2
—
—
—
0
0
550
3378
2.08
35.23
4.0
3.3
45.1
88.0
e6/l
1.66
387
2251
1184
9847
3.09
34.27
6.7
4.5
1.7
2.0
mu/l
1.17
1131
9218
434
2475
2.13
33.52
2.4
2.1
239.2
236.9
u/l
0.01
405
2355
337
1745
2.25
33.16
2.7
2.5
526.7
556.6
mosm/kgh2o
1.34
279
1503
463
2722
2.08
32.86
3.4
2.9
26.1
63.0
e6/l
2.02
357
2061
209
876
2.65
32.79
2.6
2.1
—
—
—
0
0
210
887
2.63
32.42
2.5
2.1
—
—
—
0
0
216
926
2.60
32.34
2.7
2.3
33.0
93.8
u/l
0.60
181
775
209
884
2.62
32.16
2.5
2.1
—
—
—
0
0
878
6524
2.05
31.70
3.8
3.1
—
—
—
0
0
694
4783
1.96
30.76
5.3
5.8
10.1
10.7
umol/l
0.77
658
4516
821
5994
1.99
30.69
9.3
8.7
4.2
4.0
e9/l
1.50
712
5272
425
2478
2.06
30.39
3.3
2.8
0.2
0.4
e6/l
2.08
327
1833
203
873
2.57
30.08
2.6
2.1
—
—
—
0
0
269
1315
2.32
30.05
1.8
1.7
1142.1
1169.0
nmol/l
0.16
212
1025
422
2463
2.05
30.03
3.3
2.7
—
—
—
0
0
1163
9750
2.71
29.90
4.6
3.7
5.7
5.8
mmol/l
0.33
1080
9055
344
1873
2.13
29.38
2.5
2.4
8.9
7.5
e6/l
0.55
292
1649
433
2572
2.02
29.19
6.9
6.4
—
—
—
0
0
218
986
2.45
28.95
2.1
2.0
371.3
375.9
nmol/l
0.12
194
911
728
5186
1.91
28.30
6.5
6.0
0.6
0.5
e9/l
1.17
627
4573
748
5388
1.90
27.96
7.1
6.3
0.2
0.2
e9/l
0.37
659
4824
411
2429
2.01
27.88
1.6
1.4
2.2
2.2
g/l
0.18
216
1536
728
5208
1.89
27.70
6.5
6.0
0.0
0.0
e9/l
0.47
630
4589
668
4654
1.89
27.54
10.1
8.4
0.0
0.0
e9/l
0.10
537
3843
398
2342
2.00
27.22
2.4
2.1
2.6
2.8
mg/l
0.94
324
2016
717
5129
1.88
27.02
6.4
6.0
29.1
29.3
%
0.20
681
4820
746
5406
1.88
26.97
6.5
6.0
2.0
2.0
e9/l
0.96
665
4851
690
4891
1.87
26.61
6.4
6.0
2.8
2.8
%
0.02
650
4571
670
4706
1.87
26.60
6.4
6.1
0.7
0.7
%
0.03
632
4413
91
266
3.60
26.56
1.6
1.2
—
—
—
0
0
692
4916
1.86
26.44
6.7
6.2
8.0
8.2
%
1.02
656
4639
707
5067
1.86
26.16
6.3
5.8
56.4
56.5
%
0.06
671
4779
455
2841
1.92
25.91
1.5
1.3
1.3
1.6
u/ml
0.33
102
783
65
153
4.42
25.56
5.9
5.9
377.6
370.7
umol/l
0.12
52
138
1203
10436
2.85
25.53
18.0
11.6
139.5
139.6
mmol/l
1.17
1176
10147
1204
10476
2.83
24.88
18.2
11.7
3.9
3.9
mmol/l
2.26
1174
10169
274
1456
2.11
24.43
2.9
2.6
2.4
2.4
mmol/l
0.07
248
1276
389
2367
1.91
23.54
4.7
3.8
96.4
94.5
%
0.91
376
2295
129
502
2.74
23.14
1.1
1.1
—
—
—
0
0
398
2489
1.86
21.85
1.6
1.6
1.5
1.4
mmol/l
0.52
345
2162
728
5450
1.76
21.56
5.3
4.5
6.3
6.5
mmol/l
0.90
678
4968
252
1376
2.03
20.57
3.0
2.6
4.5
3.1
e6/l
0.78
130
712
281
1604
1.96
20.17
2.3
2.6
80.1
119.7
ug/g
3.15
228
1274
161
747
2.32
19.84
5.6
3.7
1.5
1.8
mmol/l
0.50
132
606
220
1158
2.08
19.79
1.4
1.4
—
—
—
0
0
157
722
2.33
19.74
2.4
2.1
13.5
12.8
nmol/l
0.33
134
655
270
1533
1.96
19.64
3.8
3.3
403.4
563.0
ng/l
0.26
161
976
210
1096
2.09
19.29
2.2
2.7
8.1
6.9
umol/l
0.29
169
943
417
2732
1.77
19.17
3.3
3.3
8.4
8.1
mmol/l
0.31
365
2371
259
1462
1.96
19.12
2.9
2.4
1.4
1.1
e6/l
0.52
137
790
153
706
2.32
19.07
3.5
3.3
4.5
4.6
pmol/l
1.15
132
629
1048
8902
1.88
18.46
5.5
4.6
37.5
38.5
mmol/mol
2.75
981
8404
230
1261
2.00
18.40
1.2
1.2
—
—
—
0
0
837
6671
1.70
18.36
5.2
3.8
134.5
985.3
e6/l
1.10
11
87
148
686
2.30
18.23
9.8
9.3
—
—
—
0
0
243
1367
1.95
18.03
2.7
3.7
0.8
0.8
mmol/l
0.49
214
1288
150
712
2.25
17.45
7.1
7.9
1.5
1.3
mmol/l
0.90
141
682
157
760
2.21
17.41
1.5
1.4
25.0
23.2
iu/l
0.27
118
631
1087
9421
1.90
16.90
21.5
13.3
13.4
13.4
%
0.32
1070
9222
356
2302
1.75
16.75
1.9
1.9
0.8
1.0
mg/l
1.24
248
1675
1242
11340
2.81
16.66
12.0
8.8
27.2
26.6
u/l
0.30
1208
11004
870
7097
1.67
16.57
5.0
3.8
—
—
—
0
0
224
1262
1.93
16.44
1.8
2.4
29.0
29.5
s
0.89
216
1226
139
656
2.25
16.37
1.7
1.6
364.3
315.9
mu/l
0.42
115
588
455
3182
1.66
15.84
7.4
6.8
1.1
1.1
inr
1.15
154
1043
197
1079
1.97
15.66
6.2
6.1
1.1
1.1
mmol/l
0.12
177
1021
37
83
4.56
15.48
3.1
2.0
—
—
—
0
0
100
419
2.50
15.39
2.1
1.8
—
—
—
0
0
328
2117
1.73
15.34
5.3
4.0
—
—
—
0
0
42
105
4.10
15.31
1.2
1.9
—
—
—
0
0
424
2937
1.66
15.19
2.9
2.4
60.7
55.8
u/l
0.40
390
2734
66
225
3.04
15.06
1.2
1.7
326.8
605.8
e6/l
0.23
45
182
66
225
3.04
15.06
1.2
1.6
5.0
11.1
e6/l
0.69
42
175
342
2257
1.70
14.66
3.3
3.2
—
—
—
0
0
1190
10778
2.13
14.30
16.9
11.1
18.9
21.0
mg/l
1.66
933
8248
139
698
2.11
13.97
1.2
1.2
—
—
—
0
0
276
1737
1.75
13.97
1.8
1.6
52586648.2
33796721.9
pmol/l
0.14
232
1512
174
954
1.95
13.71
1.3
1.2
—
—
—
0
0
25
44
5.77
13.70
2.2
4.7
122.4
145.7
umol/l
0.15
13
30
101
450
2.35
13.59
6.4
3.8
24.1
24.1
mmol/l
0.01
93
412
339
2271
1.66
13.58
3.7
3.4
1.0
1.0
kg/l
1.79
38
292
54
176
3.16
13.31
1.9
3.6
31.5
35.3
umol/l
0.74
48
156
458
3319
1.58
13.26
2.6
2.0
—
—
—
0
0
14
13
10.87
12.87
1.6
1.5
—
—
—
0
0
1237
11470
2.39
12.47
14.3
10.1
—
—
—
0
0
523
3952
1.54
12.36
2.1
1.9
—
—
—
0
0
651
5161
1.52
12.26
5.3
4.3
0.0
0.0
estimate
0.41
131
1037
37
100
3.78
12.16
1.1
1.6
—
—
—
0
0
649
5152
1.51
12.08
3.8
3.1
0.0
0.0
estimate
0.50
122
1004
284
1867
1.67
12.07
1.4
1.3
21.1
28.1
iu/ml
0.38
78
590
380
2699
1.57
11.72
3.5
2.5
—
—
—
0
0
98
473
2.16
10.90
1.4
1.5
10.8
10.0
u/l
0.20
69
374
647
5202
1.48
10.89
3.9
3.2
0.0
0.0
estimate
0.80
127
999
269
1795
1.63
10.65
2.8
3.2
1003.3
969.8
ng/l
0.05
215
1459
55
206
2.74
10.64
1.1
1.7
—
—
—
0
0
265
1767
1.63
10.51
1.4
1.3
16.3
11.4
u/ml
0.39
84
733
115
600
2.00
10.40
4.4
3.9
105.9
76.4
ng/l
1.06
95
546
77
344
2.32
10.32
2.1
1.6
44.3
40.0
nmol/l
0.66
77
336
49
178
2.82
10.05
3.9
3.0
—
—
—
0
0
92
450
2.12
9.90
3.3
3.3
132.2
130.9
g/l
0.24
92
442
187
1162
1.71
9.67
2.0
1.6
—
—
—
0
0
171
1039
1.74
9.59
1.4
1.3
—
—
—
0
0
141
813
1.82
9.43
2.5
3.3
1.8
1.7
%
0.43
126
732
1148
10553
1.71
9.26
19.4
11.6
40.7
40.4
%
0.67
911
8519
35
110
3.24
9.22
1.7
1.4
55.3
71.7
mmol/l
1.50
26
95
37
121
3.12
9.14
1.4
1.6
—
—
—
0
0
413
3122
1.47
9.08
4.0
3.0
55.7
37.3
ng/l
0.36
217
1725
254
1732
1.58
9.06
2.0
1.6
—
—
—
0
0
136
788
1.81
8.95
1.4
1.3
237.6
240.4
u/ml
0.01
129
730
119
663
1.87
8.88
3.8
3.5
1.2
1.2
mmol/l
1.72
99
576
70
327
2.21
8.48
1.3
1.2
—
—
—
0
0
117
661
1.85
8.36
1.4
1.2
—
—
—
0
0
1120
10294
1.60
8.27
4.6
4.0
2.9
2.9
mmol/l
0.12
1040
9680
134
793
1.77
8.22
2.5
2.4
0.2
0.2
g/l
0.51
116
745
223
1524
1.56
7.80
1.6
1.3
356.5
508.6
titre
1.38
34
305
100
550
1.89
7.77
2.3
2.9
73.9
72.2
e9/l
0.15
56
403
26
76
3.47
7.69
3.5
3.3
—
—
—
0
0
63
295
2.19
7.61
1.3
1.2
—
—
—
0
0
57
257
2.27
7.54
3.5
3.1
—
—
—
0
0
1105
10180
1.54
7.47
4.2
3.7
4.7
4.7
mmol/l
0.73
1029
9656
153
966
1.66
7.41
1.3
1.2
101.9
151.2
iu/ml
1.26
39
372
96
537
1.85
7.10
2.0
2.5
67.2
67.3
g/l
0.03
85
498
1278
12303
2.54
6.94
24.8
16.1
258.7
259.1
e9/l
0.08
1251
12039
55
255
2.21
6.83
1.6
2.3
850.5
479.1
ug/l
0.24
49
235
1097
10138
1.50
6.81
4.1
3.7
1.4
1.5
mmol/l
5.14
1016
9573
1278
12318
2.49
6.64
24.7
16.0
90.2
90.0
fl
1.09
1264
12182
1278
12319
2.49
6.63
24.7
16.0
30.1
30.1
pg
0.35
1264
12182
1278
12320
2.48
6.61
24.8
16.0
4.5
4.6
e12/l
0.94
1249
12041
1278
12324
2.47
6.53
24.8
16.1
6.8
6.7
e9/l
1.77
1247
12038
1278
12329
2.45
6.43
25.0
16.1
136.2
136.5
g/l
0.43
1262
12190
165
1099
1.57
6.42
1.6
1.5
—
—
—
0
0
86
482
1.84
6.34
1.5
1.3
—
—
—
0
0
43
188
2.33
6.15
4.6
3.4
2.4
2.4
mmol/l
0.01
27
113
89
509
1.80
6.15
2.2
2.8
151.6
144.4
ng/l
0.06
74
449
79
436
1.86
6.12
1.7
1.6
—
—
—
0
0
43
189
2.32
6.08
1.1
1.1
—
—
—
0
0
1066
9852
1.44
6.08
22.1
13.6
333.4
333.3
g/l
0.14
1057
9777
26
89
2.96
6.02
1.3
1.5
280.6
284.5
mosm/kgh2o
0.30
21
70
53
257
2.11
5.92
1.9
1.5
0.6
0.4
nmol/l
0.30
46
211
124
792
1.62
5.75
2.8
2.7
10.7
10.4
g/l
0.36
109
721
68
366
1.90
5.70
1.5
1.5
—
8.8
u/ml
—
0
13
385
3077
1.36
5.65
2.1
2.2
—
—
—
0
0
12
25
4.84
5.50
1.2
1.0
—
—
—
0
0
44
206
2.18
5.40
1.1
1.1
—
—
—
0
0
40
181
2.25
5.33
4.2
3.3
—
—
—
0
0
53
269
2.01
5.28
1.4
1.5
326.6
298.9
ug/g
0.34
29
148
125
818
1.58
5.26
8.3
8.9
0.8
1.0
mmol/l
0.12
104
644
296
2300
1.37
5.14
3.8
3.1
—
—
—
0
0
39
178
2.23
5.10
1.4
1.8
0.8
0.8
g/l
0.01
25
133
1048
9740
1.38
5.08
3.7
3.4
1.4
1.3
mmol/l
3.27
973
9188
57
302
1.93
5.04
1.4
2.2
1.5
1.4
g/l
0.17
51
264
101
1550
0.62
5.01
1.2
1.3
—
—
—
0
0
75
435
1.77
4.99
1.9
2.1
—
—
—
0
0
28
111
2.56
4.98
1.3
1.4
—
—
—
0
0
13
32
4.09
4.90
1.5
2.1
10.7
16.6
umol/l
2.18
13
32
45
226
2.03
4.65
4.5
3.2
7.4
7.4
ph
0.03
40
187
46
233
2.01
4.64
1.5
1.4
109.9
105.3
u/ml
—
10
42
293
2308
1.35
4.62
3.7
4.1
9.5
10.8
mg/mmol
0.14
181
1505
132
902
1.52
4.59
2.4
2.2
3742.3
4357.7
u/l
0.12
38
341
27
110
2.49
4.56
1.2
1.3
0.3
0.4
g/l
0.59
17
75
27
110
2.49
4.56
1.2
1.3
5.9
6.5
g/l
0.40
17
77
27
110
2.49
4.56
1.2
1.3
3.2
2.7
g/l
0.86
17
75
48
249
1.96
4.54
1.6
1.4
—
—
—
0
0
41
204
2.04
4.36
1.8
1.7
—
—
—
0
0
279
2201
1.34
4.33
3.2
3.4
80.4
304.7
mg/l
1.98
175
1441
66
387
1.74
4.27
1.8
2.8
20.9
21.2
s
0.34
55
340
98
639
1.58
4.22
1.4
1.4
—
—
—
0
0
15
47
3.22
4.06
2.1
1.6
141.5
148.8
nmol/l
0.19
15
47
17
58
2.96
4.02
4.2
3.5
—
—
—
0
0
34
164
2.10
3.94
4.3
2.3
17.3
16.7
%
0.54
18
80
334
2740
1.29
3.88
4.4
3.5
0.0
0.0
estimate
0.06
120
1008
8
11
7.31
3.86
9.6
6.8
—
—
—
0
0
164
1214
1.40
3.78
1.2
1.2
—
—
—
0
0
94
625
1.54
3.74
2.1
1.7
1.4
1.3
g/l
0.14
82
576
22
92
2.42
3.57
10.3
7.8
7.8
6.7
mmol/l
0.61
22
75
29
137
2.14
3.57
3.9
2.4
—
—
—
0
0
21
88
2.41
3.40
1.3
1.4
117.4
57.6
pmol/l
—
7
27
20
82
2.46
3.39
1.2
1.3
—
—
—
0
0
115
816
1.45
3.37
15.4
16.1
1.0
1.2
inr
2.25
13
124
226
1792
1.32
3.35
3.9
4.0
1.6
2.0
ug/l
1.10
201
1629
33
170
1.97
3.26
3.2
3.4
43.2
48.1
mg/l
0.17
25
137
33
170
1.97
3.26
3.2
3.4
50.3
30.0
mg/l
0.62
25
136
20
84
2.40
3.23
1.6
1.1
—
—
—
0
0
84
566
1.52
3.18
2.6
2.3
5.3
7.0
ug/l
0.52
67
512
62
392
1.61
3.10
2.5
2.2
—
—
—
0
0
24
113
2.14
3.01
1.2
1.3
—
—
—
0
0
146
1104
1.36
2.98
1.4
1.3
—
—
—
0
0
540
4796
1.21
2.96
3.5
3.9
—
—
—
0
0
37
206
1.82
2.93
1.1
1.1
—
—
—
0
0
34
185
1.86
2.89
2.9
2.2
137.7
132.5
g/l
0.94
25
140
368
4256
0.81
2.89
2.8
2.4
—
—
—
0
0
61
923
0.64
2.88
1.4
1.3
—
—
—
0
0
38
216
1.78
2.82
4.8
2.6
23.9
24.7
mmol/l
0.42
33
191
17
71
2.41
2.80
3.6
2.6
13.1
11.6
%
1.06
17
71
23
110
2.11
2.79
1.2
1.3
—
—
nmol/l
—
0
0
163
1278
1.31
2.63
2.3
2.0
—
—
—
0
0
76
524
1.48
2.63
1.1
1.1
—
—
—
0
0
84
592
1.45
2.60
1.3
1.3
229.6
236.9
miu/ml
0.07
40
304
11
38
2.91
2.58
1.4
1.1
—
—
—
0
0
9
27
3.35
2.39
3.9
2.1
—
—
—
0
0
42
260
1.64
2.35
1.6
2.5
13.3
10.7
mg/l
0.78
37
240
42
264
1.61
2.22
3.3
3.8
1.6
1.4
mmol/l
0.49
42
259
32
188
1.72
2.18
1.3
1.3
3.4
5.0
u/ml
0.54
15
83
77
554
1.41
2.17
1.3
1.3
—
—
—
0
0
75
542
1.41
2.07
3.7
3.5
5.2
5.1
kpa
0.20
66
506
46
302
1.54
2.05
1.8
1.8
2.1
5.8
iu/l
—
8
109
120
940
1.30
1.99
4.8
3.3
—
—
—
0
0
74
538
1.40
1.99
3.7
3.5
7.4
7.4
ph
0.47
13
66
13
57
2.29
1.98
3.0
3.6
608.0
728.6
u/ml
0.23
13
57
301
2620
1.19
1.93
4.2
4.4
—
—
—
0
0
61
432
1.43
1.91
4.4
5.5
—
—
—
0
0
55
385
1.45
1.84
8.3
12.2
—
—
—
0
0
130
1042
1.27
1.83
2.4
2.6
0.5
0.7
ug/l
5.58
88
599
5
12
4.18
1.82
5.8
2.3
—
—
—
0
0
5
12
4.18
1.82
5.6
2.5
4.9
8.1
mmol/l
—
5
12
11
47
2.35
1.78
1.6
1.5
—
—
—
0
0
8
30
2.68
1.72
1.0
1.6
—
—
—
0
0
10
42
2.39
1.68
2.1
1.6
—
—
—
0
0
8
31
2.59
1.66
8.5
3.1
—
—
—
0
0
259
2255
1.19
1.65
2.2
2.4
1634.8
4724.7
umol/l
1.29
226
2007
42
287
1.48
1.61
4.9
4.7
—
—
—
0
0
22
128
1.73
1.61
4.0
3.9
—
—
—
0
0
44
305
1.46
1.58
1.2
1.3
—
796.4
—
0
11
12
57
2.12
1.55
2.0
2.8
18.6
593.1
ug/l
0.69
12
49
50
358
1.41
1.52
1.4
1.2
—
—
—
0
0
15
79
1.91
1.49
1.2
1.2
—
—
—
0
0
32
210
1.54
1.49
1.3
1.2
—
—
—
0
0
22
132
1.68
1.46
1.2
1.1
1.7
1.5
g/l
1.13
16
116
16
87
1.85
1.46
1.0
1.0
—
—
—
0
0
264
2338
1.16
1.37
2.2
2.1
—
—
—
0
0
8
162
0.49
1.36
1.4
1.6
—
—
—
0
0
5
17
2.95
1.36
2.0
1.8
—
—
—
0
0
5
17
2.95
1.36
1.0
1.6
—
—
—
0
0
5
17
2.95
1.36
1.0
1.0
—
—
—
0
0
297
2656
1.15
1.36
2.0
1.7
—
—
—
0
0
19
112
1.71
1.35
1.6
1.6
—
—
—
0
0
16
90
1.79
1.33
2.1
3.0
—
—
—
0
0
36
250
1.45
1.32
2.4
2.4
5.1
5.7
umol/l
0.20
27
185
6
24
2.51
1.30
1.5
1.3
—
—
—
0
0
8
34
2.36
1.29
1.0
1.1
—
33.2
—
0
5
10
48
2.09
1.28
1.8
1.4
—
—
—
0
0
47
346
1.37
1.26
1.1
1.1
—
—
—
0
0
9
45
2.01
1.23
1.0
3.4
—
—
—
0
0
10
49
2.05
1.22
1.1
1.1
0.3
1.6
u/ml
—
5
28
31
213
1.47
1.21
2.2
2.4
—
—
—
0
0
335
3045
1.13
1.20
3.8
2.7
—
—
—
0
0
28
189
1.49
1.19
4.9
3.5
—
—
—
0
0
15
86
1.75
1.19
2.5
2.5
—
—
—
0
0
30
206
1.47
1.18
1.1
1.0
1.7
2.3
u/ml
0.24
12
102
90
734
1.24
1.16
1.8
2.4
3.9
4.1
e9/l
0.39
73
617
39
283
1.39
1.15
1.5
1.3
190.6
222.9
u/ml
0.55
26
174
15
87
1.73
1.15
2.5
2.4
4.0
4.0
mmol/l
0.01
15
87
15
87
1.73
1.15
2.5
2.4
105.6
105.4
mmol/l
0.04
15
87
32
224
1.44
1.15
1.8
2.6
0.7
0.9
nmol/l
0.82
27
193
16
95
1.69
1.14
1.1
1.1
0.2
2.5
u/ml
—
8
33
44
327
1.36
1.13
2.5
4.0
0.2
0.3
g/l
2.03
16
151
7
30
2.34
1.12
1.7
3.2
—
—
—
0
0
22
143
1.55
1.12
1.5
1.4
—
—
—
0
0
5
21
2.39
1.09
4.2
1.1
—
—
—
0
0
28
194
1.45
1.07
1.2
1.1
—
—
—
0
0
20
129
1.56
1.06
1.1
1.1
—
—
—
0
0
24
163
1.48
1.02
2.4
3.2
—
—
—
0
0
12
68
1.77
1.00
1.0
1.2
—
—
—
0
0
16
99
1.62
1.00
2.8
3.6
—
—
—
0
0
5
23
2.18
0.98
2.6
2.0
—
—
—
0
0
10
54
1.86
0.96
1.7
1.4
31.6
33.2
g/l
—
10
46
52
410
1.28
0.93
3.6
2.7
—
—
—
0
0
19
127
1.50
0.88
2.4
2.3
—
—
—
0
0
27
194
1.40
0.88
1.0
1.2
—
—
—
0
0
150
1322
1.15
0.87
1.9
1.9
—
—
—
0
0
25
178
1.41
0.86
1.2
1.2
—
—
—
0
0
8
45
1.78
0.84
1.4
1.5
—
8.9
—
0
5
0
25
0.00
0.79
0.0
1.1
—
39.1
—
0
16
0
26
0.00
0.78
0.0
1.0
—
—
—
0
0
9
53
1.70
0.75
1.6
1.6
—
—
—
0
0
9
54
1.67
0.74
1.1
2.4
—
—
—
0
0
19
133
1.43
0.73
1.6
1.4
—
—
—
0
0
7
38
1.85
0.73
2.1
1.5
—
—
—
0
0
7
40
1.75
0.71
1.4
1.9
—
—
—
0
0
79
675
1.18
0.71
2.7
4.2
3.9
24.6
ug/l
0.98
61
520
5
26
1.93
0.70
1.8
6.5
25.5
24.6
mmol/l
—
5
26
15
101
1.49
0.70
1.0
1.1
0.2
6.1
u/ml
—
7
30
7
42
1.67
0.68
1.0
1.4
—
—
—
0
0
5
92
0.54
0.67
2.8
3.9
—
—
—
0
0
7
44
1.59
0.65
1.4
2.3
237.1
223.5
e6/l
—
7
26
11
71
1.55
0.62
1.8
2.8
94.1
33.3
mg/l
—
6
48
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
24
310
0.77
0.59
4.4
7.6
—
—
—
0
0
28
219
1.28
0.59
1.5
1.5
—
—
—
0
0
38
309
1.24
0.58
1.2
1.1
7.3
7.3
u/ml
0.00
22
170
6
35
1.72
0.57
1.0
4.1
—
—
—
0
0
11
73
1.51
0.56
1.5
1.3
—
—
—
0
0
6
37
1.62
0.55
1.0
1.3
—
—
—
0
0
10
65
1.54
0.55
1.9
2.1
—
1.9
—
0
9
21
272
0.77
0.54
1.0
1.1
—
—
—
0
0
21
272
0.77
0.54
1.0
1.1
—
—
—
0
0
11
74
1.49
0.53
1.0
1.1
—
—
—
0
0
82
729
1.13
0.48
3.9
4.6
0.0
0.1
%
1.18
15
165
7
111
0.63
0.48
1.1
1.8
—
—
—
0
0
19
242
0.78
0.45
1.1
1.0
0.2
5.4
u/ml
—
6
92
15
112
1.34
0.44
1.2
1.7
—
—
—
0
0
12
86
1.40
0.44
1.1
1.2
—
—
—
0
0
19
148
1.29
0.43
1.7
1.6
—
—
—
0
0
26
212
1.23
0.42
2.4
3.7
4.3
4.1
e9/l
0.23
26
212
39
332
1.18
0.42
1.2
1.1
1.2
2.1
u/ml
0.32
17
137
0
16
0.00
0.41
0.0
7.6
—
0.4
—
0
16
5
34
1.47
0.40
1.8
1.7
—
—
—
0
0
5
35
1.43
0.39
1.2
1.1
—
—
—
0
0
10
71
1.41
0.39
1.0
1.1
—
—
—
0
0
5
36
1.39
0.38
1.2
1.7
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
5
37
1.35
0.37
1.0
1.0
—
—
—
0
0
51
450
1.14
0.36
1.5
1.7
—
—
—
0
0
26
217
1.20
0.35
2.4
3.9
58.4
56.5
%
0.39
26
217
29
245
1.19
0.35
1.7
1.4
31.1
21.8
u/l
0.59
24
204
42
478
0.87
0.34
1.5
1.5
—
—
—
0
0
30
256
1.18
0.33
3.5
3.2
13.4
714.8
u/ml
0.72
25
220
6
86
0.70
0.33
1.7
1.2
—
—
—
0
0
6
88
0.68
0.33
1.3
1.2
—
—
—
0
0
34
294
1.16
0.32
1.2
1.1
0.9
1.4
u/ml
0.45
17
129
11
83
1.33
0.32
1.5
1.3
—
—
—
0
0
22
183
1.21
0.32
1.3
1.4
—
—
—
0
0
76
695
1.10
0.31
3.8
3.2
—
—
—
0
0
11
84
1.31
0.30
1.0
1.7
32.1
32.5
pg
0.07
11
84
12
93
1.29
0.30
1.4
2.2
—
43.7
—
0
10
7
57
1.23
0.29
1.0
1.1
2175.7
1770.5
miu/ml
—
7
57
16
131
1.22
0.27
1.4
1.2
13.0
28.4
u/l
0.93
16
109
83
770
1.08
0.27
4.5
3.5
—
—
—
0
0
5
71
0.70
0.26
3.4
2.9
—
—
—
0
0
44
397
1.11
0.25
3.8
3.6
—
—
—
0
0
42
465
0.90
0.24
1.5
1.4
—
—
—
0
0
10
78
1.28
0.24
1.3
1.4
—
—
—
0
0
42
464
0.90
0.24
1.5
1.4
—
—
—
0
0
65
603
1.08
0.22
3.6
2.2
—
—
—
0
0
82
768
1.07
0.22
4.0
4.5
0.2
0.1
%
0.10
17
199
14
116
1.21
0.22
1.5
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
16.1
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
56.4
—
0
5
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
13
108
1.21
0.20
2.5
2.3
—
—
—
0
0
17
146
1.17
0.19
1.3
1.3
—
—
—
0
0
6
52
1.15
0.19
1.3
2.0
—
—
—
0
0
10
81
1.24
0.18
1.3
2.6
536.8
562.3
e6/l
—
10
66
8
71
1.13
0.16
1.3
1.2
—
—
—
0
0
8
72
1.11
0.16
2.4
2.0
—
—
—
0
0
176
1816
0.96
0.15
1.5
1.5
—
—
—
0
0
9
78
1.15
0.15
1.7
1.3
—
69.1
—
0
9
9
79
1.14
0.15
1.3
2.6
0.2
0.2
e9/l
—
9
67
78
742
1.05
0.15
3.4
4.1
0.4
0.5
%
0.48
11
156
7
88
0.79
0.14
1.1
1.1
—
—
—
0
0
7
88
0.79
0.14
1.7
1.5
0.9
1.0
g/l
—
7
88
216
2106
1.03
0.14
2.1
1.7
—
—
—
0
0
84
805
1.05
0.13
3.9
4.4
0.6
0.9
%
0.68
17
217
24
219
1.10
0.12
1.8
1.9
—
—
—
0
0
20
220
0.91
0.12
1.1
1.0
1.5
7.1
u/ml
—
5
91
25
231
1.08
0.10
1.2
1.3
—
—
—
0
0
31
290
1.07
0.10
1.1
1.1
0.2
3.9
u/ml
—
5
74
5
45
1.11
0.09
2.6
3.0
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
194.6
200.7
iu/ml
—
5
46
22
204
1.08
0.08
4.8
3.4
21.9
25.4
mg/l
0.28
15
130
5
64
0.78
0.08
1.6
1.1
—
—
—
0
0
7
66
1.06
0.08
1.3
1.1
—
—
—
0
0
84
816
1.03
0.08
1.4
1.6
—
—
—
0
0
8
75
1.07
0.07
2.1
1.7
5.6
6.1
mmol/l
—
8
57
13
118
1.10
0.07
1.1
1.1
—
—
—
0
0
351
3483
1.01
0.05
1.6
1.6
—
—
—
0
0
17
160
1.06
0.04
3.1
2.5
—
—
—
0
0
13
123
1.06
0.01
1.6
1.5
—
—
—
0
0
13
123
1.06
0.01
1.6
1.5
—
—
—
0
0
13
123
1.06
0.01
1.6
1.5
—
—
—
0
0
13
123
1.06
0.01
1.6
1.5
—
—
—
0
0
20
194
1.03
0.00
2.5
2.4
93.1
134.8
ug/min
0.38
12
121
71
708
1.00
0.00
1.5
1.4
—
—
—
0
0
20
201
0.99
0.00
1.6
1.7
1091.4
13383.2
e6/l
—
9
150
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
2.5
2.4
54.7
50.2
umol/l
—
6
52
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
6
66
0.91
0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
187.3
—
0
6
7
69
1.01
0.00
1.4
1.3
—
—
—
0
0
5
55
0.91
0.00
1.6
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint F5_SLEEP_NOS and mortality.

Females

Parameter HR [95% CI] p-value
F5_SLEEP_NOS 1.915 [1.54, 2.39] < 0.001
Birth year 0.99 [0.98, 1.0] 0.021

During the follow-up period (1.1.1998 — 31.12.2019), 311 out of 4213 females with F5_SLEEP_NOS died.

Males

Parameter HR [95% CI] p-value
F5_SLEEP_NOS 2.307 [1.88, 2.83] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 416 out of 4613 males with F5_SLEEP_NOS died.

Mortality risk

Mortality risk for people of age

years, who have F5_SLEEP_NOS.

N-year risk Females Males
1 0.166% 0.436%
5 1.021% 2.599%
10 2.371% 6.311%
15 4.257% 11.178%
20 7.481% 18.768%

Relationships between endpoints

Index endpoint: F5_SLEEP_NOS – Sleep disorders, other/unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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