This is a non-core endpoint: only basic statistics are computed.
Malignant neoplasm of oesophagus
C3_OESOPHAGUS
esophageal squamous cell carcinoma: Esophageal squamous cell carcinoma (ESCC) is a type of esophageal carcinoma (EC; see this term) that can affect any part of the esophagus, but is usually located in the upper or middle third.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
986 |
4. Check minimum number of eventsNone |
986 |
5. Include endpointsNone |
986 |
6. Filter based on genotype QC (FinnGen only) |
961 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of oesophagus
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of oesophagus, including Hilmo
- Malignant neoplasm of digestive organs
- Solid cancers, helper endpoint
- Malignant neoplasm
- Malignant neoplasm, wide definition for exclusion
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 961 | 204 | 757 |
| Unadjusted period prevalence (%) | 0.29 | 0.07 | 0.35 |
| Median age at first event (years) | 69.60 | 70.28 | 69.42 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 986
- Matched controls
- 9860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
31.3
320.3
219
89
L01BC06
ATC
capecitabine; oral
+∞
312.6
283
*
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
105.1
307.7
263
34
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
+∞
307.7
340
*
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
95.4
307.7
228
31
A03FA01
ATC
metoclopramide; systemic, rectal
34.4
307.7
635
492
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
16.9
307.7
786
1857
N02AA05
ATC
oxycodone; systemic
12.5
307.7
530
837
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
94.2
307.7
178
23
A04AA01
ATC
ondansetron; systemic, rectal
52.0
307.7
253
65
Z51.5
ICD-10 Finland
Palliative care
34.7
307.7
383
177
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
855.2
307.7
376
7
WX302
NOMESCO Finland
Thoracal epidural anesthesy
46.5
307.7
264
77
JN4BD
NOMESCO Finland
Extensive body CT
22.0
307.7
331
221
R4190
NOMESCO Finland
Nutritional therapy
45.8
307.7
246
71
H02AB02
ATC
dexamethasone; systemic
173.3
307.7
442
46
A04AA02
ATC
granisetron; systemic, transdermal
4259.2
307.7
312
*
130
Kela drug reimbursment
Malignant tumour
+∞
307.7
674
*
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
+∞
307.7
693
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
47.3
304.3
182
47
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
+∞
288.1
262
*
8070/3-C15.9
ICD-O-3
Squamous cell carcinoma, NOS, of esophagus, NOS
+∞
286.9
261
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
1696.4
273.2
253
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.7
242.4
255
245
UJC12
NOMESCO Finland
Flexible oesophagoscopy
67.3
234.1
129
22
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
58.5
233.2
132
26
C15.4
ICD-10 Finland
Malignant neoplasm: Middle third of oesophagus
+∞
231.7
213
*
R13
ICD-10 Finland
Dysphagia
10.9
228.3
291
366
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
222.6
205
*
JN4AD
NOMESCO Finland
Body CT examination
11.8
220.9
259
290
K22.2
ICD-10 Finland
Oesophageal obstruction
48.9
217.6
128
30
XX3DW
NOMESCO Finland
Time consuming IT work
13.6
214.0
222
207
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
13.9
194.0
195
172
8140/3-C15.9
ICD-O-3
Adenocarcinoma, NOS, of esophagus, NOS
+∞
183.2
170
*
WF002
NOMESCO Finland
Radical radiotherapy
314.0
182.5
180
7
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
178.7
166
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
97.7
170.8
89
10
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
21.2
164.7
128
69
JDB10
NOMESCO Finland
Percutaneous gastrostomy
48.2
163.3
96
22
8140/3-C15.5
ICD-O-3
Adenocarcinoma, NOS, of lower third of esophagus
+∞
152.1
142
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
147.7
138
*
WX600
NOMESCO Finland
Single shot through catheter
190.1
142.8
146
9
JD1EE
NOMESCO Finland
Ultrasound examination of gastro-oesophageal reflux
521.4
140.0
136
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
1494.2
136.8
130
*
WZC00
NOMESCO Finland
Treatment plan or consultation
5.0
135.8
464
1488
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
132.3
124
*
WW500
NOMESCO Finland
Blood transfusion
17.5
126.7
107
68
JN4CD
NOMESCO Finland
Very extensive body CT
23.2
125.9
93
44
C15.1
ICD-10 Finland
Malignant neoplasm: Thoracic part of oesophagus
+∞
125.8
118
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
16.3
122.1
107
73
C15.3
ICD-10 Finland
Malignant neoplasm: Upper third of oesophagus
+∞
120.3
113
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
272.8
119.8
120
5
A04AA55
ATC
palonosetron, combinations; systemic
+∞
108.4
102
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
244.7
108.0
109
5
A06AH03
ATC
naloxegol; oral
46.4
103.1
61
14
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
52.2
102.3
59
12
C15.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of oesophagus
+∞
100.8
95
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.2
98.4
367
1211
ZXE40
NOMESCO Finland
More than seven and less than nine hours
13.5
98.0
95
77
JCC10
NOMESCO Finland
Transthoracic partial oesophagectomy without interposition
1036.3
97.8
94
*
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
33.0
95.7
62
20
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
999.7
94.5
91
*
C15.0
ICD-10 Finland
Malignant neoplasm: Cervical part of oesophagus
+∞
93.2
88
*
WX402
NOMESCO Finland
General anaesthesia
4.3
87.2
290
871
ZX120
NOMESCO Finland
Intravenous
6.0
86.1
171
334
ZXE30
NOMESCO Finland
More than five and less than seven hours
8.0
84.3
122
171
WF001
NOMESCO Finland
Preoperative radiotherapy
+∞
81.4
77
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.2
79.0
265
795
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.4
77.9
175
381
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
15.8
77.4
68
46
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
15.1
76.5
69
49
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
73.9
70
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
73.9
70
*
WZC30
NOMESCO Finland
Teaching
4.3
73.5
227
638
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
71.8
68
*
L03AA13
ATC
pegfilgrastim; parenteral
258.6
71.3
72
*
D77
ICPC
Malignant digestive neopl other/NOS
727.6
69.9
68
*
UJD02
NOMESCO Finland
Gastroscopy
6.1
69.4
131
242
A04AD12
ATC
aprepitant; systemic
+∞
68.5
65
*
L03AA02
ATC
filgrastim; parenteral
152.8
67.9
71
5
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
+∞
67.5
64
*
A02BC02
ATC
pantoprazole; systemic
3.8
67.1
787
5005
K22.1
ICD-10 Finland
Ulcer of oesophagus
9.9
66.5
79
86
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.4
65.3
115
198
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
60.0
57
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
6.8
59.1
97
155
ZX090
NOMESCO Finland
Other technic of radiotherapy
132.2
58.5
62
5
8070/3-C15.5
ICD-O-3
Squamous cell carcinoma, NOS, of lower third of esophagus
+∞
57.9
55
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.9
57.8
196
583
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
13.5
56.7
54
42
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
55.8
53
*
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
18.1
55.2
45
26
C61
ICD-10 Finland
Malignant neoplasm of prostate
292.0
54.8
55
*
JDA55
NOMESCO Finland
Endoscopic dilatation of stomach, pylorus or anastomosis of stomach
89.6
53.5
59
7
ZX070
NOMESCO Finland
Intensity modified radiotherapy
546.1
53.0
52
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
52.6
50
*
B01AB05
ATC
enoxaparin; parenteral
2.9
52.3
378
1764
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
6.8
51.5
84
133
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
51.4
311
1317
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
10.4
51.1
58
59
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
268.7
50.6
51
*
RD210, ,
NOMESCO Finland
14.1
50.5
47
35
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
+∞
50.4
48
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
48.3
572
3382
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
5.3
46.7
99
202
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
9.1
45.6
57
66
C16.00
ICD-10 Finland
Cardia
+∞
45.1
43
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
44.4
292
1280
R4110
NOMESCO Finland
Physiotherapy
2.7
44.1
334
1574
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.0
42.4
59
78
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
153.3
42.1
44
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
117.8
42.1
45
*
C15.2
ICD-10 Finland
Malignant neoplasm: Abdominal part of oesophagus
+∞
42.0
40
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
42.0
40
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
40.9
39
*
N02AA01
ATC
morphine; systemic, rectal
10.4
39.2
44
44
K22.7
ICD-10 Finland
Barrett oesophagus
7.8
38.9
55
74
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.7
38.4
93
212
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
5.1
38.1
84
177
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.6
37.8
94
219
B01AB10
ATC
tinzaparin; parenteral
4.0
37.8
118
327
8070/3-C15.4
ICD-O-3
Squamous cell carcinoma, NOS, of middle third of esophagus
+∞
37.7
36
*
A79
ICPC
Malignancy NOS
197.4
37.0
38
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
36.7
35
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
36.1
172
625
B01AB04
ATC
dalteparin; parenteral
5.0
35.6
80
171
C16.09
ICD-10 Finland
Malignant tumor of cardiac or other unspecified carcinoma
+∞
34.6
33
*
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
59.5
34.4
40
7
D84
ICPC
Oesophagus disease
47.4
34.0
41
9
1CD01, ,
NOMESCO Finland
+∞
33.5
32
*
T18.1
ICD-10 Finland
Foreign body in oesophagus
12.6
33.4
33
27
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
13.2
33.3
32
25
A02BC05
ATC
esomeprazole; systemic
2.2
33.2
442
2616
WX872
NOMESCO Finland
Intensive care
3.7
32.7
113
335
GD1AD
NOMESCO Finland
Thorax CT examination
4.0
31.2
94
253
ZXE00
NOMESCO Finland
One hour or less
2.2
31.1
401
2326
WX002
NOMESCO Finland
Sedation and analgesia
2.5
31.1
245
1150
TJD20
NOMESCO Finland
Change of gastrostomy tube
72.3
31.1
35
5
116
Kela drug reimbursment
Prostate cancer
+∞
30.4
29
*
JFF00
NOMESCO Finland
Catheter enterostomy
+∞
29.3
28
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.6
29.0
32
31
TPH07
NOMESCO Finland
Cathetrisation of artery
2.9
28.9
151
574
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
28.3
27
*
8000/3-C15.9
ICD-O-3
Neoplasm, malignant of esophagus, NOS
+∞
28.3
27
*
JCA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in oesophagus
289.4
27.9
28
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
27.2
26
*
JDB00
NOMESCO Finland
Gastrostomy
143.9
26.8
28
*
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
26.6
26.3
36
14
K92.0
ICD-10 Finland
Haematemesis
4.8
26.0
61
135
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
96.0
25.8
28
*
JAH00
NOMESCO Finland
Laparotomy
5.7
25.8
49
90
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
36.7
25.3
32
9
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
25.1
24
*
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
+∞
25.1
24
*
C15
ICD-10 Finland
Malignant neoplasm of oesophagus
+∞
25.1
24
*
J01MA12
ATC
levofloxacin; systemic
2.3
25.0
228
1132
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
8.3
24.9
33
41
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
49.7
24.4
29
6
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
24.1
23
*
8140/3-C15.2
ICD-O-3
Adenocarcinoma, NOS, of abdominal esophagus
+∞
24.1
23
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
24.1
23
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
128.1
23.7
25
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
34.3
23.4
30
9
ZXD05
NOMESCO Finland
Urgent procedure
2.1
23.4
328
1922
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.2
23.2
64
161
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
23.0
22
*
TJF00
NOMESCO Finland
Insertion of jejunal tube
+∞
23.0
22
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
66.6
22.9
26
*
Z98.8
ICD-10 Finland
Other specified postsurgical states
8.8
22.9
29
34
AA1BD
NOMESCO Finland
Extensive CT of head and brain
6.6
22.8
37
58
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
235.2
22.7
23
*
R11
ICD-10 Finland
Nausea and vomiting
3.1
22.7
100
344
A98
ICPC
Health maint/preventive medicine
0.5
22.4
666
7977
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.3
22.0
58
141
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
4.1
21.8
61
155
K22.9
ICD-10 Finland
Disease of oesophagus, unspecified
20.6
21.8
32
16
PJA12
NOMESCO Finland
Sentinel node biopsy
224.8
21.7
22
*
JAH01
NOMESCO Finland
Laparoscopy
5.6
21.3
41
76
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
21.1
379
2403
N05BA06
ATC
lorazepam; systemic, sublingual
3.4
21.1
79
246
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
20.9
20
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
20.9
20
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
214.3
20.7
21
*
A06AD11
ATC
lactulose; oral
2.2
20.4
198
1001
Z3226
NOMESCO Finland
Physiotherapist
2.2
20.0
197
1001
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
19.9
19
*
WB111
NOMESCO Finland
Multiple neoadjuvant cytostatic therapy
+∞
19.9
19
*
JFF01
NOMESCO Finland
Laparoscopic catheter enterostomy
+∞
19.9
19
*
JN6AD
NOMESCO Finland
CT of torso and neck
20.5
19.1
28
14
N03AX16
ATC
[U] pregabalin
2.1
19.0
236
1309
C16.9
ICD-10 Finland
Malignant neoplasm: Stomach, unspecified
+∞
18.8
18
*
PJD53
NOMESCO Finland
Block dissection of aortic lymph nodes
+∞
18.8
18
*
D21
ICPC
Swallowing problem
5.7
18.8
35
63
JCA98
NOMESCO Finland
Other local endoscopic operation on oesophagus
39.2
18.6
23
6
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
193.5
18.6
19
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.5
18.5
66
199
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
18.4
327
2048
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
8.0
18.3
25
32
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
6.1
18.3
32
54
R50.9
ICD-10 Finland
Fever, unspecified
2.3
18.3
156
745
WW200, ,
SPAT
0.3
18.2
51
1553
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
15.7
18.0
29
19
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.1
17.8
49
123
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
17.8
17
*
Z51.0
ICD-10 Finland
Radiotherapy session
183.2
17.6
18
*
Z2221
NOMESCO Finland
Medical doctor
2.0
17.5
246
1420
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
7.9
17.5
24
31
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.4
17.4
130
585
C10AA07
ATC
rosuvastatin; oral
0.4
17.3
120
2410
RD160, ,
NOMESCO Finland
64.5
16.8
19
*
GBB00
NOMESCO Finland
Tracheostomy
6.6
16.7
27
42
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
16.7
16
*
L02AE02
ATC
leuprorelin; implant, parenteral
91.7
16.6
18
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
28.1
16.5
22
8
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
48.3
16.1
19
*
WC125
NOMESCO Finland
Demanding cytostatic therapy of local tumor recidive
+∞
15.7
15
*
1505A
ICD-9 Finland
Malignant neoplasm of oesophagus, Lower third of oesophagus
+∞
15.7
15
*
L01BC53
ATC
tegafur, combinations; systemic
+∞
15.7
15
*
8144/3-C16.0
ICD-O-3
Adenocarcinoma, intestinal type of cardia, NOS
+∞
15.7
15
*
JCC30
NOMESCO Finland
Transthoracic partial oesophagectomy with interposition of intestine
86.5
15.6
17
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
162.5
15.5
16
*
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
5.7
15.1
28
50
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
15.0
137
671
SPAT1109
SPAT
Analgesia with portable analgesic pump
25.5
14.7
20
8
JCF00
NOMESCO Finland
Insertion of prosthetic tube into oesphagus
+∞
14.6
14
*
178
Kela drug reimbursment
Combination product containing tegafur, gimeracil and oteracil
+∞
14.6
14
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
14.6
14
*
L02BB03
ATC
bicalutamide; oral
+∞
14.6
14
*
115
Kela drug reimbursment
Breast cancer
+∞
14.6
14
*
8070/3-C15.3
ICD-O-3
Squamous cell carcinoma, NOS, of upper third of esophagus
+∞
14.6
14
*
WX882
NOMESCO Finland
High dependency care
4.1
14.4
39
97
WX704
NOMESCO Finland
Intubation
2.6
13.8
80
319
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.4
13.7
34
79
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.3
13.6
50
1348
D00.1
ICD-10 Finland
Carcinoma in situ: Oesophagus
+∞
13.6
13
*
C16.04
ICD-10 Finland
Malignant tumor of cardiac intestinal carcinoma
+∞
13.6
13
*
8144/3-C15.9
ICD-O-3
Adenocarcinoma, intestinal type of esophagus, NOS
+∞
13.6
13
*
UGB02
NOMESCO Finland
Tracheoscopy
141.9
13.5
14
*
Z3231
NOMESCO Finland
Registered nurse
1.8
13.5
248
1547
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.3
13.2
50
157
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
50.7
12.9
15
*
T05
ICPC
Feeding problem of adult
10.7
12.8
24
23
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.4
12.7
47
145
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
5.3
12.5
25
48
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
12.5
12
*
JCA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in oesophagus
131.6
12.5
13
*
Z43.1
ICD-10 Finland
Attention to gastrostomy
131.6
12.5
13
*
N05CF01
ATC
zopiclone; oral
1.7
12.3
316
2155
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
12.2
136
716
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
12.0
320
2204
WX730
NOMESCO Finland
Conventional respirator
4.9
12.0
26
54
N02AX02
ATC
tramadol; systemic, rectal
1.6
11.9
408
2988
JCB00
NOMESCO Finland
Oesophagostomy
65.7
11.6
13
*
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
5.3
11.6
23
44
UJC02
NOMESCO Finland
Rigid oesophagoscopy
11.3
11.6
21
19
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
11.5
11
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
+∞
11.5
11
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
11.5
11
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
11.5
11
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
11.5
11
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
121.4
11.4
12
*
GBA35
NOMESCO Finland
Endoscopic insertion of stent into trachea
121.4
11.4
12
*
JCC00
NOMESCO Finland
Transhiatal partial oesophagectomy without interposition
121.4
11.4
12
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
121.4
11.4
12
*
R52.0
ICD-10 Finland
Acute pain
3.7
11.3
35
96
K22.3
ICD-10 Finland
Perforation of oesophagus
17.3
11.2
17
10
C10AX09
ATC
ezetimibe; oral
0.4
11.2
52
1263
NK6AN
NOMESCO Finland
Total body bone isotope imaging
25.3
11.2
15
6
N02AA03
ATC
hydromorphone; systemic, rectal
43.8
10.9
13
*
C10AA05
ATC
atorvastatin; oral
0.6
10.9
262
3698
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
18.0
10.7
16
9
L03
ICPC
Low back symptom/complaint
0.4
10.7
71
1492
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.9
10.7
31
81
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
111.2
10.4
11
*
JX1XB
NOMESCO Finland
Other X-ray examination of alimentary tract with contrast
111.2
10.4
11
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
10.4
10
*
C16.0
ICD-10 Finland
Malignant neoplasm: Cardia
+∞
10.4
10
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
10.4
10
*
8144/3-C15.5
ICD-O-3
Adenocarcinoma, intestinal type of lower third of esophagus
+∞
10.4
10
*
8010/3-C15.9
ICD-O-3
Carcinoma, NOS, of esophagus, NOS
+∞
10.4
10
*
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
19.0
10.3
15
8
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
10.2
32
89
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
11.4
10.1
18
16
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
4.9
10.0
22
46
J01MA14
ATC
moxifloxacin; systemic
2.1
10.0
96
477
K20
ICD-10 Finland
Oesophagitis
3.9
10.0
29
76
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.2
9.7
87
421
R4130
NOMESCO Finland
Speech therapy
3.4
9.7
35
107
JCC96
NOMESCO Finland
Other partial oesophagectomy
101.0
9.4
10
*
Y77
ICPC
Malignant neoplasm prostate
101.0
9.4
10
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
30.3
9.4
12
*
1CD02, ,
NOMESCO Finland
+∞
9.4
9
*
GCA32
NOMESCO Finland
Endoscopic insertion of stent into bronch
+∞
9.4
9
*
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
+∞
9.4
9
*
C16.03
ICD-10 Finland
Malignant tumor of cardiac diffuse carcinoma
+∞
9.4
9
*
C78.1
ICD-10 Finland
Secondary malignant neoplasm of mediastinum
+∞
9.4
9
*
FM1FN
NOMESCO Finland
Heart function isotope examination
+∞
9.4
9
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
9.4
9
*
384
Kela drug reimbursment
Combination product containing tegafur, gimeracil and oteracil
+∞
9.4
9
*
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
+∞
9.4
9
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
9.4
9
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
9.4
9
*
JDD00
NOMESCO Finland
Total gastrectomy and Roux-en-Y oesophagojejunostomy
+∞
9.4
9
*
WX892
NOMESCO Finland
Monitored bed care
2.1
9.3
87
428
M25.5
ICD-10 Finland
Pain in joint
0.5
9.2
98
1750
N06DX01
ATC
memantine; oral
0.2
9.1
14
621
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
0.5
9.0
113
1920
SPAT1255
SPAT
Intravenous administration of medicine
2.2
8.9
72
334
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
8.7
110
604
GDC00
NOMESCO Finland
Lobectomy of lung
50.4
8.7
10
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
50.4
8.7
10
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.8
8.6
41
148
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.2
8.6
33
105
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
27.8
8.5
11
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.4
8.4
60
264
J86.09
ICD-10 Finland
Pyothorax with fistula
90.8
8.4
9
*
OAB44, ,
SPAT
0.2
8.4
6
356
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
8.3
8
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
8.3
8
*
L01CB01
ATC
etoposide; systemic
+∞
8.3
8
*
WB101
NOMESCO Finland
Simple cytostatic neoadjuvant therapy
+∞
8.3
8
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
8.3
8
*
C79.31
ICD-10 Finland
Secondary malignant tumor of the cerebellum
+∞
8.3
8
*
L15
ICPC
Knee symptom/complaint
0.5
8.3
71
1367
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
8.2
76
1428
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
6.6
8.2
20
31
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
11.8
8.1
14
12
KCD02
NOMESCO Finland
Transurethral resection of bladder
10.1
8.0
15
15
WPB10
NOMESCO Finland
Making a convalescent care decision
22.2
8.0
11
5
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.5
8.0
48
195
ZX100
NOMESCO Finland
Oral
4.5
7.9
19
43
G47.3
ICD-10 Finland
Sleep apnoea
0.5
7.9
94
1632
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
4.0
7.9
22
56
UJD10, ,
SPAT
3.5
7.9
26
75
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.6
7.8
138
2147
N05AD01
ATC
haloperidol; systemic
2.7
7.8
42
162
K92.1
ICD-10 Finland
Melaena
2.2
7.8
64
300
M79.6
ICD-10 Finland
Pain in limb
0.6
7.7
176
2572
WZC30, ,
SPAT
0.2
7.7
5
319
J86.9
ICD-10 Finland
Pyothorax without fistula
6.0
7.7
20
34
EB4VA, ,
NOMESCO Finland
0.2
7.7
8
377
R63.4
ICD-10 Finland
Abnormal weight loss
2.5
7.7
46
187
KA1FN
NOMESCO Finland
Isotope renography
12.0
7.6
13
11
L02BG04
ATC
letrozole; oral
25.2
7.6
10
*
WPA15
NOMESCO Finland
Palliative care consultation with the patient and loved ones
25.2
7.6
10
*
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
25.2
7.6
10
*
E0000UV, ,
ATC
1.5
7.6
325
2446
A28
ICPC
Limited function/disability NOS
1.6
7.4
183
1217
JN4DD
NOMESCO Finland
Scout CT scan of torso
80.7
7.4
8
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
7.3
198
1346
ZZR00
NOMESCO Finland
Flap of skin
11.0
7.3
13
12
K22.0
ICD-10 Finland
Achalasia of cardia
11.0
7.3
13
12
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
+∞
7.3
7
*
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
7.3
7
*
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
7.3
7
*
GBB13
NOMESCO Finland
Revision of tracheostomy
+∞
7.3
7
*
1504A
ICD-9 Finland
Malignant neoplasm of oesophagus, Middle third of oesophagus
+∞
7.3
7
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
7.3
7
*
8070/3-C15.0
ICD-O-3
Squamous cell carcinoma, NOS, of cervical esophagus
+∞
7.3
7
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
9.4
7.3
14
15
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
7.2
89
486
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
7.2
71
358
P20
ICPC
Memory disturbance
0.5
7.2
57
1130
GAA31
NOMESCO Finland
Thoracoscopy
30.2
7.2
9
*
N07BC02
ATC
methadone; systemic
30.2
7.2
9
*
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
12.1
7.1
12
10
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
5.7
7.1
19
34
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
11.0
6.8
12
11
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.7
6.8
18
32
HAB40
NOMESCO Finland
Wedge excision of mammary gland
16.8
6.8
10
6
JCA42
NOMESCO Finland
Other endoscopic procedure for hemostasis
22.7
6.7
9
*
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.8
6.7
20
54
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.6
6.6
37
146
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.6
6.6
37
146
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
3.0
6.6
28
95
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
4.2
6.6
17
41
OAB42, ,
SPAT
0.3
6.6
17
553
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.5
72
378
N40
ICD-10 Finland
Hyperplasia of prostate
0.6
6.5
176
2492
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.6
6.5
108
1713
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
0.6
6.5
87
1463
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
70.3
6.4
7
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
70.3
6.4
7
*
XX1AD
NOMESCO Finland
Other CT-examination
70.3
6.4
7
*
GWW96
NOMESCO Finland
Other reoperation in thoracic surgery
70.3
6.4
7
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
70.3
6.4
7
*
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
14.4
6.4
10
7
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
14.4
6.4
10
7
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.6
6.4
169
2405
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.3
552
4684
L13
ICPC
Hip symptom/complaint
0.5
6.3
56
1073
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.9
6.3
76
412
Z53.0
ICD-10 Finland
Procedure not carried out because of contraindication
18.1
6.3
9
5
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
6.3
6
*
JCE96
NOMESCO Finland
Other reconstruction of oesophagus
+∞
6.3
6
*
1506
Kela drug reimbursment
The combination of trifluridine and tipiracil
+∞
6.3
6
*
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
6.3
6
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
6.3
6
*
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
+∞
6.3
6
*
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
+∞
6.3
6
*
TJX90
NOMESCO Finland
Other minor procedure in gastroenterological surgery
+∞
6.3
6
*
C16.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of stomach
+∞
6.3
6
*
8480/3-C15.5
ICD-O-3
Mucinous adenocarcinoma of lower third of esophagus
+∞
6.3
6
*
JC004
NOMESCO Finland
Palliative radiotherapy of oesophagus
+∞
6.3
6
*
X76
ICPC
Malignant neoplasm breast female
+∞
6.3
6
*
WB131
NOMESCO Finland
Very demanding neoadjuvant cytostatic therapy
+∞
6.3
6
*
3018
Kela drug reimbursment
The combination of trifluridine and tipiracil
+∞
6.3
6
*
8070/3-C15.1
ICD-O-3
Squamous cell carcinoma, NOS, of thoracic esophagus
+∞
6.3
6
*
8246/3-C15.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of esophagus, NOS
+∞
6.3
6
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
6.3
6
*
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
+∞
6.3
6
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
6.3
6
*
8070/3-C02.1
ICD-O-3
Squamous cell carcinoma, NOS, of border of tongue
+∞
6.3
6
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
6.3
6
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
+∞
6.3
6
*
YN7AD
NOMESCO Finland
CT examination of spine for dose design of radiotherapy
+∞
6.3
6
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
8145/3-C16.0
ICD-O-3
Carcinoma, diffuse type of cardia, NOS
+∞
6.3
6
*
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
+∞
6.3
6
*
TJW99
NOMESCO Finland
Other minor procedure in gastrointestinal endoscopy
26.9
6.2
8
*
R01AD09
ATC
mometasone; nasal
0.7
6.2
177
2480
WX610
NOMESCO Finland
Patient controlled analgesia
12.6
6.1
10
8
SDA02
NOMESCO Finland
Periodontal treatment, brief
0.6
6.1
126
1897
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
6.1
6.0
15
25
UJC01
NOMESCO Finland
Scopy of lower throat
5.6
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
254
139
24.27
307.65
3.8
1.8
1072.34
51.46
u/ml
1.22
241
104
518
373
28.15
307.65
4.6
1.4
41.46
2.75
ug/l
2.00
472
276
184
78
28.77
263.68
4.1
1.7
500.72
34.99
u/ml
0.91
170
70
467
1091
7.23
209.43
5.5
2.8
0.78
0.83
mmol/l
18.03
459
1006
320
579
7.70
181.73
3.0
2.0
0.19
0.20
g/l
0.96
306
518
379
988
5.61
143.65
5.4
5.7
0.93
1.02
mmol/l
7.99
369
904
673
3123
4.64
115.61
9.7
3.9
31.18
35.32
g/l
52.29
662
2856
438
1593
4.15
103.21
4.1
2.2
—
—
—
0
0
693
3550
4.20
97.15
14.1
4.0
10.75
12.88
umol/l
3.86
686
3330
255
726
4.39
81.86
3.8
7.2
6.88
10.94
mmol/l
17.25
244
680
487
2244
3.31
74.34
6.3
2.1
2.33
2.35
mmol/l
1.15
457
1846
597
3104
3.34
74.24
4.4
2.4
—
—
—
0
0
288
983
3.73
70.59
13.1
6.1
104.48
104.21
mmol/l
0.35
288
983
677
3877
3.38
69.88
13.6
19.2
1.19
1.41
inr
9.75
158
1112
657
3819
3.16
63.59
15.1
6.1
4.39
4.47
e9/l
0.32
596
3291
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
127
256
5.55
61.09
2.3
2.8
0.28
0.33
u/ml
1.06
59
150
310
1326
2.95
50.16
6.4
2.1
2.51
2.44
mmol/l
19.34
288
1118
162
517
3.55
42.33
1.7
1.6
—
—
—
0
0
582
3613
2.49
42.15
12.4
5.9
1.20
1.21
mmol/l
2.51
506
3081
541
3317
2.40
39.29
11.5
5.4
1.19
1.20
mmol/l
4.56
517
2954
669
4532
2.48
38.38
10.7
4.6
6.73
6.91
mmol/l
1.96
659
4251
394
2151
2.39
36.67
3.9
2.8
35.09
37.68
u/l
0.28
384
2034
228
970
2.76
35.88
16.8
7.0
11.77
11.32
kpa
0.89
223
921
226
969
2.73
34.94
16.8
7.0
1.23
1.24
mmol/l
0.00
204
753
402
2258
2.32
34.56
3.1
2.4
231.80
60.67
u/l
0.49
389
2073
592
7583
0.45
30.80
4.1
5.5
2.53
2.58
mmol/l
0.63
526
6919
129
433
3.28
30.71
17.2
10.3
—
—
—
0
0
741
5536
2.36
29.83
15.1
5.5
99.85
76.53
u/l
10.40
726
5103
255
1250
2.40
29.23
1.7
1.9
30.11
30.14
s
0.03
249
1204
105
320
3.55
29.07
2.1
1.8
1.03
1.85
ug/l
0.87
97
281
548
7172
0.47
28.91
5.6
6.5
40.68
41.12
mmol/mol
0.55
491
6594
571
7334
0.47
27.68
3.7
4.8
1.39
1.37
mmol/l
0.42
506
6685
579
7399
0.47
27.61
3.7
4.8
4.36
4.40
mmol/l
0.40
523
6784
170
707
2.70
27.41
2.6
2.5
12.48
9.60
umol/l
0.53
158
614
256
1296
2.32
27.00
1.9
1.8
—
—
—
0
0
146
589
2.74
24.86
2.4
2.3
32.55
40.83
u/l
0.51
129
487
126
472
2.91
24.65
1.5
1.5
—
—
—
0
0
43
74
6.03
24.16
1.2
1.2
—
—
—
0
0
231
1189
2.23
23.00
2.3
2.5
9.34
12.81
umol/l
10.08
223
1087
190
925
2.31
21.49
1.9
1.8
—
—
—
0
0
479
3270
1.90
21.39
4.6
5.7
20.67
26.18
%
20.27
461
3035
187
929
2.25
20.06
1.8
1.8
—
—
—
0
0
206
1079
2.15
19.31
2.0
2.5
2.25
2.24
g/l
0.15
194
988
197
1024
2.15
18.79
2.1
2.6
17.05
23.02
%
6.30
168
863
575
7105
0.54
18.70
3.6
4.3
1.32
1.31
mmol/l
0.11
516
6427
461
3241
1.79
17.60
4.5
5.5
62.94
58.37
%
10.09
445
3011
348
2255
1.84
17.37
3.0
3.0
41.15
91.53
e6/l
0.96
279
1739
322
2047
1.85
17.02
2.9
3.0
1.28
0.43
e6/l
0.82
253
1554
304
1911
1.85
16.58
2.1
2.2
3.57
2.92
mg/l
2.77
268
1592
114
499
2.45
16.19
1.9
1.6
—
—
—
0
0
34
71
4.92
15.52
1.9
3.5
3.16
1.50
%
0.77
29
61
19
5
38.72
15.42
1.1
1.2
—
—
—
0
0
202
1178
1.90
13.60
2.8
2.8
2.44
1.43
e6/l
0.88
123
649
364
2564
1.67
12.61
3.5
3.5
58.84
112.12
e6/l
1.40
284
1851
146
782
2.02
12.54
2.7
2.6
230.17
238.61
u/l
0.36
138
729
34
89
3.92
11.72
1.3
1.6
1172.84
1975.61
e6/l
0.96
25
66
262
3716
0.60
11.20
3.6
3.7
21.58
24.22
%
2.36
120
1770
355
4620
0.64
10.06
3.8
3.8
2.32
1.99
ug/l
1.28
306
4136
30
81
3.79
9.93
1.4
1.6
69708.95
104859.25
e6/l
0.15
19
51
367
2711
1.56
9.87
3.0
3.0
—
—
—
0
0
200
1271
1.72
9.85
2.6
2.6
1.98
1.00
e6/l
1.60
117
739
235
1575
1.65
9.43
2.3
2.4
7.03
3.82
e6/l
1.81
217
1398
416
5186
0.66
9.25
3.5
3.3
15.11
15.02
pmol/l
0.27
376
4597
562
6580
0.66
9.01
3.9
4.1
2.04
2.02
mu/l
0.12
501
5867
111
613
1.91
8.65
4.8
2.4
69.89
62.68
ml/min/173m2
0.87
46
224
115
643
1.89
8.63
2.0
1.6
59.95
66.83
g/l
9.34
109
585
238
1648
1.59
8.23
3.6
4.1
173.20
529.37
ng/l
2.86
212
1417
48
193
2.56
8.18
1.6
1.8
—
—
—
0
0
68
323
2.19
7.99
7.4
4.0
1.21
1.44
mmol/l
1.90
68
318
45
178
2.60
7.93
1.2
1.4
—
—
—
0
0
45
178
2.60
7.93
1.2
1.4
—
—
—
0
0
662
7410
0.68
7.32
4.4
5.0
6.12
6.15
mmol/l
0.29
617
6669
48
1017
0.44
7.23
1.1
1.2
2.27
13.70
u/ml
4.13
16
364
57
265
2.22
7.08
2.1
3.1
—
—
—
0
0
17
27
6.39
6.95
3.0
1.4
—
—
—
0
0
43
179
2.47
6.85
1.6
2.0
76.47
86.71
%
1.54
43
172
553
4667
1.42
6.73
3.9
4.2
177.00
2232.10
e6/l
—
10
78
209
2869
0.66
6.72
3.5
3.9
10.04
8.42
mg/mmol
0.21
141
1904
31
111
2.85
6.63
2.5
3.2
64.97
58.41
%
1.77
31
111
54
1061
0.48
6.59
1.1
1.3
59.01
38.57
iu/ml
0.55
15
311
129
810
1.68
6.52
3.3
3.3
3.04
2.10
mmol/l
1.50
109
682
185
2579
0.65
6.34
2.8
2.7
0.68
0.74
ug/l
0.57
128
1732
49
225
2.24
6.29
1.3
1.2
—
—
—
0
0
24
79
3.09
5.95
1.1
1.1
—
—
—
0
0
343
2705
1.41
5.93
2.7
2.7
190.43
162.19
ug/l
0.73
315
2450
139
2032
0.63
5.87
1.7
1.6
1.29
1.38
mmol/l
0.87
122
1668
12
15
8.08
5.85
2.9
1.5
120.58
69.07
nmol/l
0.46
12
15
205
2755
0.68
5.73
2.7
3.3
7.47
7.99
mmol/l
0.88
169
2303
36
151
2.44
5.69
1.7
1.6
—
—
—
0
0
60
316
1.96
5.42
1.8
1.6
—
—
—
0
0
93
563
1.72
5.38
6.0
3.2
1.22
1.22
mmol/l
0.21
88
472
28
109
2.61
5.17
2.4
3.0
5.32
4.61
e9/l
0.62
28
109
18
55
3.31
5.04
1.4
1.6
—
—
—
0
0
25
93
2.73
5.03
1.4
1.3
—
—
—
0
0
55
289
1.96
5.02
1.7
1.5
—
—
—
0
0
29
118
2.50
4.91
1.4
1.4
—
—
—
0
0
38
178
2.18
4.71
1.4
1.5
288.53
280.73
ug/g
0.10
30
108
26
104
2.54
4.57
1.4
1.3
—
—
—
0
0
25
99
2.56
4.49
1.4
1.4
—
—
—
0
0
16
437
0.36
4.42
1.9
1.9
—
—
—
0
0
26
110
2.40
4.09
1.2
1.5
—
—
—
0
0
13
31
4.24
4.02
1.0
1.3
—
—
—
0
0
32
150
2.17
4.00
1.3
1.5
—
—
—
0
0
23
93
2.51
3.98
1.3
1.5
—
—
—
0
0
250
1984
1.35
3.90
1.7
1.5
19.33
20.05
nmol/l
0.37
234
1662
19
71
2.71
3.84
1.4
1.7
—
—
—
0
0
32
155
2.10
3.70
1.3
1.5
—
—
—
0
0
10
20
5.04
3.69
1.3
2.1
—
—
—
0
0
9
262
0.34
3.60
1.1
1.4
—
—
—
0
0
21
458
0.45
3.47
1.9
2.6
—
18.14
—
0
22
122
877
1.45
3.40
1.8
2.5
4.05
7.93
ug/l
5.41
103
774
12
33
3.67
3.30
1.6
1.5
—
—
—
0
0
12
33
3.67
3.30
1.6
1.5
—
—
—
0
0
187
1459
1.35
3.22
1.6
1.6
2.17
1.28
mg/l
2.36
159
1123
18
72
2.53
3.22
1.8
1.2
—
—
—
0
0
14
49
2.88
3.20
1.6
2.1
—
—
—
0
0
135
1001
1.40
3.18
1.8
1.9
1.91
1.75
%
0.64
121
874
767
8106
0.76
3.15
49.9
20.4
118.30
138.16
g/l
156.60
756
7924
767
8105
0.76
3.14
49.5
20.2
4.03
4.54
e12/l
94.28
743
7789
767
8102
0.76
3.10
49.5
20.2
265.04
234.98
e9/l
18.82
747
7822
767
8100
0.76
3.07
52.6
20.4
35.49
40.69
%
73.08
725
7411
19
407
0.46
3.02
1.1
1.4
—
52.36
—
0
25
108
779
1.43
2.98
6.0
3.3
—
—
—
0
0
12
41
2.95
2.62
1.6
1.4
—
—
—
0
0
28
150
1.89
2.53
2.3
2.1
60.32
64.98
%
0.54
28
150
61
409
1.52
2.45
2.3
2.5
1.12
0.24
e6/l
1.20
61
400
13
51
2.57
2.45
1.5
1.5
—
—
—
0
0
16
70
2.31
2.42
1.4
1.2
—
—
—
0
0
204
1675
1.27
2.41
1.9
1.8
1160.53
1154.30
nmol/l
0.03
164
1272
16
71
2.27
2.35
1.4
1.2
—
—
—
0
0
16
71
2.27
2.35
1.4
1.2
—
—
—
0
0
9
218
0.41
2.32
1.2
1.8
—
—
—
0
0
21
108
1.96
2.16
2.2
2.2
3.95
4.14
mmol/l
0.77
21
108
21
108
1.96
2.16
2.2
2.2
102.86
105.42
mmol/l
1.24
21
108
10
237
0.42
2.13
1.1
1.3
—
—
—
0
0
9
31
2.92
2.07
1.0
1.3
—
—
—
0
0
5
10
5.02
2.07
1.0
1.2
—
—
—
0
0
0
55
0.00
2.07
0.0
1.4
—
58.00
—
0
5
0
57
0.00
2.05
0.0
1.4
—
295.00
—
0
6
20
105
1.92
1.96
1.2
1.4
—
—
—
0
0
20
105
1.92
1.96
1.2
1.4
—
—
—
0
0
17
84
2.04
1.96
5.8
4.6
—
—
—
0
0
28
164
1.73
1.96
2.8
2.4
13.49
16.29
%
2.09
16
91
8
28
2.87
1.86
3.8
3.9
—
—
—
0
0
137
1676
0.79
1.84
2.9
3.7
1.02
1.02
kg/l
0.03
17
259
15
73
2.07
1.81
1.5
1.2
—
—
—
0
0
16
80
2.02
1.80
1.2
1.5
—
—
—
0
0
16
80
2.02
1.80
1.2
1.5
—
—
—
0
0
377
3386
1.18
1.80
2.2
2.0
84.25
92.45
pmol/l
2.94
239
1814
15
74
2.04
1.75
1.5
1.2
—
—
—
0
0
14
267
0.52
1.69
2.0
1.8
40.07
41.89
nmol/l
0.14
14
253
759
7256
1.20
1.64
37.0
14.0
44.07
26.30
mg/l
32.39
736
5685
24
143
1.70
1.62
1.3
1.2
—
—
—
0
0
99
1231
0.78
1.53
1.2
1.2
4.22
1.55
u/ml
0.50
21
323
362
3280
1.16
1.50
3.9
3.9
35.38
72.39
ng/l
1.52
300
2490
79
1008
0.76
1.50
4.0
4.9
30.30
32.36
%
1.22
56
667
17
293
0.57
1.49
1.5
1.6
—
306.25
—
0
16
482
4465
1.16
1.48
3.4
3.1
94.81
53.23
u/l
5.02
457
4070
184
2130
0.83
1.46
2.5
2.6
3433.98
7647.73
umol/l
0.69
156
1833
755
7836
0.84
1.45
18.7
9.3
24.92
27.19
u/l
1.36
738
7479
241
2723
0.85
1.44
3.2
3.7
—
—
—
0
0
225
2552
0.85
1.41
1.9
2.2
570.06
275.58
u/l
0.52
217
2374
322
3550
0.86
1.40
3.1
3.5
0.00
0.00
estimate
-0.00
66
557
14
74
1.90
1.39
1.5
1.2
—
—
—
0
0
9
41
2.21
1.37
1.1
1.1
—
—
—
0
0
5
17
2.95
1.36
1.2
1.2
—
—
—
0
0
29
191
1.53
1.36
3.3
2.7
7.20
7.79
kpa
0.97
29
186
320
3502
0.87
1.23
4.3
4.6
0.00
0.00
estimate
-0.00
67
579
323
3526
0.88
1.19
3.0
3.5
0.00
0.00
estimate
0.50
68
624
0
34
0.00
1.16
0.0
1.1
—
—
—
0
0
28
191
1.48
1.15
2.8
2.1
121.70
132.81
g/l
1.46
20
141
89
1079
0.81
1.14
12.7
6.8
—
—
—
0
0
8
155
0.51
1.14
1.0
1.2
—
—
—
0
0
13
219
0.59
1.10
1.7
1.6
8612.71
16226.36
e6/l
—
7
159
762
7855
0.87
1.07
43.4
17.2
3.94
4.02
mmol/l
14.37
752
7607
26
179
1.46
1.03
3.7
3.1
7.21
7.43
mmol/l
0.20
26
174
63
503
1.27
1.01
2.7
3.4
3.68
1.84
mmol/l
2.19
48
370
22
147
1.51
1.01
1.3
1.8
—
—
—
0
0
10
175
0.57
0.99
1.1
1.2
—
65.96
—
0
8
24
340
0.70
0.95
1.3
1.3
—
—
—
0
0
47
365
1.30
0.94
1.2
1.6
1.66
1.50
g/l
0.77
38
318
12
197
0.60
0.94
1.3
1.5
1.25
1.15
g/l
0.43
12
188
11
182
0.60
0.90
1.0
1.2
495.91
510.84
mg/l
0.08
11
170
9
154
0.58
0.89
1.1
1.1
—
—
—
0
0
762
7828
0.88
0.89
43.1
17.1
138.24
139.76
mmol/l
39.20
753
7592
12
192
0.62
0.86
1.2
1.5
0.23
0.23
g/l
0.13
12
185
12
72
1.67
0.85
1.0
1.3
—
—
—
0
0
14
88
1.60
0.84
1.9
1.5
—
—
—
0
0
10
57
1.76
0.84
1.1
1.2
—
—
—
0
0
10
57
1.76
0.84
1.1
1.2
—
—
—
0
0
10
57
1.76
0.84
1.1
1.2
—
—
—
0
0
8
46
1.75
0.82
1.0
1.7
14.14
14.56
umol/l
—
8
41
54
663
0.80
0.82
2.0
2.2
11.71
15.01
nmol/l
1.98
45
584
16
235
0.68
0.79
1.7
1.4
—
—
—
0
0
9
148
0.60
0.79
1.1
1.3
—
—
—
0
0
6
33
1.82
0.79
1.0
1.2
—
—
—
0
0
26
191
1.37
0.77
3.7
3.0
1.86
1.68
mmol/l
0.36
26
186
6
34
1.77
0.76
1.0
1.2
—
—
—
0
0
0
28
0.00
0.76
0.0
1.0
—
—
—
0
0
5
24
2.09
0.74
1.2
2.9
—
6647.80
—
0
5
5
25
2.00
0.72
1.2
1.4
—
—
—
0
0
5
25
2.00
0.72
1.4
2.0
—
—
—
0
0
7
39
1.80
0.72
1.0
1.3
—
—
—
0
0
7
39
1.80
0.72
1.0
1.3
—
—
—
0
0
519
5410
0.91
0.72
3.0
4.0
20.17
12.45
mm/h
12.99
469
4927
10
157
0.63
0.69
1.0
1.2
3.62
3.98
mmol/l
—
10
147
7
42
1.67
0.68
1.0
1.0
—
—
—
0
0
179
1955
0.90
0.65
3.1
3.7
0.00
0.01
estimate
0.50
58
549
11
70
1.58
0.65
1.0
1.3
—
—
—
0
0
10
62
1.62
0.65
1.8
2.1
—
—
—
0
0
12
176
0.68
0.62
1.7
1.7
—
—
—
0
0
5
30
1.67
0.61
2.4
2.5
36780.00
41263.33
ug/l
—
5
30
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
50
419
1.20
0.59
3.9
3.5
47.14
48.99
%
0.23
50
412
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
6
35
1.72
0.57
1.0
1.1
—
—
—
0
0
6
36
1.67
0.56
2.0
1.7
411.83
679.72
e6/l
—
6
36
6
37
1.63
0.55
1.7
2.4
—
—
—
0
0
12
171
0.70
0.55
2.2
1.5
—
—
—
0
0
8
124
0.64
0.55
1.0
1.1
—
—
—
0
0
19
250
0.76
0.54
1.0
1.0
—
—
—
0
0
6
38
1.58
0.54
2.3
1.4
203.50
73.56
pmol/l
—
6
38
336
3525
0.93
0.51
2.4
2.2
—
—
—
0
0
16
118
1.36
0.50
1.9
1.9
1.86
1.74
mmol/l
0.11
16
113
21
268
0.78
0.49
1.5
2.1
217.20
112.89
ug/min
0.56
12
163
7
110
0.63
0.48
1.0
1.1
—
—
—
0
0
8
56
1.43
0.42
1.0
1.1
—
—
—
0
0
5
33
1.52
0.41
1.8
2.3
9222.00
1058.03
u/ml
—
5
33
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
0.69
—
0
11
5
34
1.47
0.40
22.8
11.9
1101.20
1324.29
nmol/l
—
5
34
600
6128
0.95
0.35
44.4
16.3
15.71
15.30
%
1.54
591
5975
5
80
0.62
0.35
1.4
1.3
87.70
172.08
pmol/l
—
5
80
275
2641
1.06
0.32
2.7
3.1
1308.22
1712.39
ng/l
1.86
246
2262
19
156
1.22
0.31
1.4
1.4
—
—
—
0
0
21
175
1.20
0.30
1.1
1.5
—
—
—
0
0
12
93
1.29
0.30
1.1
1.1
—
—
—
0
0
17
205
0.83
0.28
1.6
1.6
0.05
0.12
iu/ml
—
7
47
24
205
1.17
0.27
3.3
3.2
0.82
0.84
nmol/l
0.11
19
158
24
205
1.17
0.27
1.3
1.1
—
—
—
0
0
681
6907
0.95
0.26
36.2
12.9
85.85
75.39
ml/min/173m2
34.80
621
5584
24
206
1.17
0.26
1.3
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
184.58
—
0
12
5
43
1.16
0.21
1.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
85.13
—
0
8
0
13
0.00
0.21
0.0
1.0
—
79.00
—
0
8
28
249
1.13
0.21
1.4
1.5
28.93
36.00
mg/l
1.02
23
198
29
324
0.89
0.20
1.3
1.4
—
—
—
0
0
33
297
1.11
0.20
1.1
1.2
124.85
124.08
iu/ml
—
10
108
28
250
1.12
0.20
1.4
1.5
49.58
49.93
mg/l
0.01
23
197
8
70
1.14
0.16
1.4
1.3
—
—
—
0
0
78
819
0.95
0.15
2.4
3.2
200.92
248.55
ng/l
0.64
70
757
8
96
0.83
0.13
1.3
1.4
—
107.90
—
0
12
266
2713
0.97
0.13
2.2
2.2
71.79
76.68
nmol/l
1.88
243
2347
10
87
1.15
0.09
1.1
1.2
128.20
113.66
%
—
10
77
68
655
1.04
0.09
1.4
1.3
—
—
—
0
0
6
54
1.11
0.09
1.2
1.4
74.17
95.11
umol/l
—
6
54
78
755
1.04
0.08
1.9
1.8
1.93
1.68
%
0.65
59
637
28
265
1.06
0.07
1.3
1.2
—
—
—
0
0
17
181
0.94
0.05
1.2
1.4
0.81
0.81
nmol/l
0.01
17
151
54
544
0.99
0.00
3.3
4.0
76.73
97.32
ng/l
1.55
48
479
180
1803
1.00
0.00
1.7
1.7
418.59
36785158.26
pmol/l
1.92
149
1468
5
55
0.91
0.00
1.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.24
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
1.61
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
30.60
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
8
79
1.01
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
17.43
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
22.03
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.2
50.00
47.11
u/l
—
5
45
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_OESOPHAGUS – Malignant neoplasm of oesophagus
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).