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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_RENAL_PELVIS_EXALLC for full statistics.

Malignant neoplasm of renal pelvis

DOID Endpoint Browser

C3_RENAL_PELVIS

renal pelvis carcinoma: A carcinoma arising in the renal pelvis. The majority of renal pelvis carcinomas are transitional cell and less frequently squamous cell carcinomas.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C65
  • Cause of death: ICD-9 — 1891
  • Cause of death: ICD-8 — 1891
  • Cancer registry: Topography ICD-O-3 — C65
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

186

4. Check minimum number of events

None

186

5. Include endpoints

None

186

6. Filter based on genotype QC (FinnGen only)

186

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 186 51 135
Unadjusted period prevalence (%) 0.05 0.02 0.06
Median age at first event (years) 71.99 70.91 72.40

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
173
Matched controls
1728
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C65
ICD-10 Finland
Malignant neoplasm of renal pelvis
13394.5
207.5
156
*
8120/3-C65.9
ICD-O-3
Transitional cell carcinoma, NOS, of renal pelvis
+∞
189.0
145
*
UKC02
NOMESCO Finland
Cystoscopy
27.2
75.6
143
257
KAC20
NOMESCO Finland
Nephroureterectomy
+∞
61.1
55
*
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
136.5
54.7
56
6
KAC21
NOMESCO Finland
Percutaneous endoscopic nephroureterectomy
+∞
52.9
48
*
R31
ICD-10 Finland
Unspecified haematuria
14.0
49.6
102
161
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
21.5
33.4
50
32
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
22.2
27.4
40
23
UKA02
NOMESCO Finland
Retrograde ureteronephroscopy
75.9
23.6
26
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
17.8
23.5
37
26
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
32.6
23.2
30
11
C66
ICD-10 Finland
Malignant neoplasm of ureter
224.6
20.0
20
*
KCD02
NOMESCO Finland
Transurethral resection of bladder
13.4
19.8
35
32
UKB02
NOMESCO Finland
Retrograde ureteroscopy
30.3
19.8
26
10
130
Kela drug reimbursment
Malignant tumour
6.1
15.4
45
94
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
18.7
15.3
23
14
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
12.6
15.1
27
25
WX302
NOMESCO Finland
Thoracal epidural anesthesy
8.0
13.5
31
46
B01AB10
ATC
tinzaparin; parenteral
6.3
13.1
36
69
7126
FHL
Nephroureterectomy
+∞
12.7
12
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
7.0
12.4
31
52
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
16.2
12.1
19
13
KCD32
NOMESCO Finland
Cystoscopic destruction of tumour of bladder
18.1
12.0
18
11
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
20.8
11.8
17
9
8000/3-C65.9
ICD-O-3
Neoplasm, malignant of renal pelvis
+∞
11.6
11
*
8130/3-C65.9
ICD-O-3
Papillary urothelial carcinoma of renal pelvis
+∞
10.5
10
*
1891C
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Renal pelvis[NEOPLASMA MALIGNUM PELVIS RENIS,MUU/TARK MÄÄR SYÖPÄ]
+∞
10.5
10
*
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
9.0
10.2
21
26
Z51.5
ICD-10 Finland
Palliative care
5.5
10.1
30
63
A04AA02
ATC
granisetron; systemic, transdermal
6.8
10.0
25
42
B02AA02
ATC
tranexamic acid; systemic
4.5
9.8
36
95
JN4AD
NOMESCO Finland
Body CT examination
5.0
9.8
32
75
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.8
9.2
42
136
A03FA01
ATC
metoclopramide; systemic, rectal
3.2
8.8
52
205
TPH07
NOMESCO Finland
Cathetrisation of artery
3.7
8.8
40
129
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.5
7.7
27
68
ZX136
NOMESCO Finland
Intravesicalis
19.4
7.7
11
6
KAC10
NOMESCO Finland
Total nephrectomy with capsule
14.2
7.5
12
9
U06
ICPC
Haematuria
6.8
7.5
18
29
D41.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Ureter
+∞
7.3
7
*
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
16.7
7.3
11
7
KH1AD
NOMESCO Finland
CT of urinary organs
6.6
7.0
17
28
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
23.6
6.7
9
*
B01AB05
ATC
enoxaparin; parenteral
2.5
6.7
66
347
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
12.9
6.7
11
9
J01EA01
ATC
trimethoprim; systemic
2.6
6.6
54
256
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.7
6.6
28
85
N02AA05
ATC
oxycodone; systemic
2.8
6.5
46
199
KC1GB
NOMESCO Finland
Cystography with X-ray
11.6
6.4
11
10
KA3GB
NOMESCO Finland
Retrograde pyelography
+∞
6.3
6
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
13.2
6.2
10
8
JN4BD
NOMESCO Finland
Extensive body CT
3.1
6.0
34
128

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
80
76
17.72
79.17
6.4
3.4
—
—
—
0
0
94
468
3.04
12.56
5.1
3.4
—
—
—
0
0
28
84
3.75
8.32
9.1
8.7
—
—
—
0
0
66
330
2.55
8.03
4.7
2.9
3.3
4.0
e6/l
0.52
60
288
85
488
2.37
7.55
4.2
4.5
—
—
—
0
0
101
645
2.24
6.75
5.8
4.4
32.1
34.4
g/l
3.23
91
606
32
120
3.01
6.67
1.3
1.5
—
—
—
0
0
60
310
2.38
6.63
4.7
3.2
554.0
583.2
mosm/kgh2o
0.61
52
266
80
475
2.20
6.30
6.8
3.7
125.8
224.9
e6/l
0.29
69
371
68
391
2.17
5.69
7.1
3.4
—
—
—
0
0
43
204
2.44
5.65
7.3
6.1
5.2
5.0
kpa
0.49
38
194
43
205
2.43
5.59
7.3
6.1
13.1
11.6
kpa
1.06
38
196
70
418
2.08
5.24
7.1
3.5
0.2
0.5
e6/l
1.85
61
314
83
528
2.03
5.23
7.3
4.2
104.0
123.3
e6/l
0.17
72
392
42
204
2.37
5.22
7.4
6.2
-0.6
1.1
mmol/l
1.22
27
158
98
668
1.99
5.02
8.7
5.9
1.2
1.2
mmol/l
0.50
90
594
29
124
2.59
4.70
5.4
3.8
—
—
—
0
0
115
848
1.93
4.48
6.4
4.8
6.8
6.9
mmol/l
0.30
107
806
94
649
1.91
4.48
10.4
9.9
1.5
1.4
inr
0.41
25
166
120
914
1.88
4.06
8.0
4.6
—
—
—
0
0
71
462
1.87
3.95
3.3
2.8
—
—
—
0
0
72
472
1.86
3.91
4.1
3.2
2.3
2.3
mmol/l
0.93
61
404
99
736
1.74
3.39
11.4
9.2
4.9
4.4
e9/l
0.62
91
637
6
8
7.70
3.07
1.2
1.0
—
—
—
0
0
64
434
1.72
2.96
5.4
4.2
7.4
7.4
ph
0.37
15
86
25
124
2.17
2.93
4.8
3.5
—
—
—
0
0
71
503
1.67
2.77
2.8
2.3
—
—
—
0
0
26
137
2.04
2.62
10.8
8.6
—
—
—
0
0
9
25
3.73
2.61
2.0
1.2
408.7
1726.1
e6/l
—
9
18
23
118
2.08
2.48
4.7
3.9
90.8
96.7
ng/l
0.14
18
103
40
249
1.77
2.46
1.8
1.7
29.8
29.5
s
0.09
40
240
11
40
2.86
2.42
2.3
2.3
1.8
1.8
mg/l
0.00
11
33
6
13
4.73
2.29
1.5
1.7
—
—
—
0
0
27
153
1.89
2.23
5.4
4.2
2.1
1.9
mmol/l
0.05
15
119
22
118
1.98
2.12
1.8
1.7
399.0
395.8
nmol/l
0.02
22
103
34
211
1.75
2.11
2.6
2.9
1.5
1.8
%
1.00
29
189
7
22
3.26
1.90
1.4
1.5
—
—
—
0
0
5
12
4.25
1.83
3.0
2.0
—
—
—
0
0
9
35
2.65
1.82
2.4
2.7
—
—
—
0
0
26
156
1.77
1.81
1.5
1.3
—
—
—
0
0
26
156
1.77
1.81
5.8
4.1
—
—
—
0
0
81
641
1.47
1.78
6.3
4.2
0.0
0.0
estimate
0.00
22
104
27
169
1.70
1.63
2.2
4.4
87.5
49.6
ug/l
0.17
21
142
79
632
1.43
1.60
6.9
5.5
0.0
0.0
estimate
0.00
21
111
16
86
1.94
1.56
6.8
3.0
—
—
—
0
0
41
290
1.53
1.53
7.4
4.6
1.0
1.0
kg/l
—
9
43
6
21
2.92
1.52
1.8
1.3
—
—
—
0
0
58
442
1.45
1.51
2.8
3.2
111.3
197.5
mg/l
0.27
41
303
58
442
1.45
1.51
2.8
3.2
6.5
7.4
mmol/l
1.08
45
359
14
73
1.99
1.48
2.3
1.4
—
—
—
0
0
42
301
1.51
1.47
4.8
4.0
28.5
235.1
ng/l
1.96
34
260
5
16
3.18
1.44
1.0
1.1
—
—
—
0
0
5
16
3.18
1.44
3.4
2.9
—
—
—
0
0
13
68
1.98
1.37
2.5
2.5
—
—
—
0
0
0
37
0.00
1.36
0.0
1.5
—
246.9
—
0
24
78
638
1.38
1.34
5.9
5.8
1.6
1.8
e9/l
0.67
68
557
20
122
1.72
1.34
6.2
3.0
5.4
5.0
kpa
0.78
15
111
10
48
2.14
1.30
5.7
4.0
—
—
—
0
0
48
363
1.43
1.29
7.3
4.6
0.0
0.0
estimate
0.00
16
105
8
35
2.34
1.28
3.6
3.0
—
—
—
0
0
6
25
2.45
1.25
1.3
1.5
—
—
—
0
0
0
33
0.00
1.17
0.0
1.2
—
—
—
0
0
44
334
1.42
1.15
7.6
6.7
—
—
—
0
0
9
163
0.53
1.15
1.0
1.3
—
—
—
0
0
76
632
1.34
1.14
6.2
4.2
0.0
0.0
estimate
0.00
22
113
39
291
1.43
1.12
1.4
1.3
—
—
—
0
0
20
129
1.62
1.11
2.2
1.5
—
—
—
0
0
5
21
2.42
1.09
4.8
5.4
13.9
11.9
mg/l
—
5
21
75
628
1.33
1.06
5.9
5.7
0.7
0.6
e9/l
1.21
66
532
58
469
1.34
1.04
3.6
3.9
14.5
10.0
mg/mmol
0.62
38
311
5
22
2.31
1.04
3.6
3.0
—
—
—
0
0
5
22
2.31
1.04
5.4
1.1
—
—
—
0
0
75
630
1.32
1.04
5.9
5.8
0.0
0.0
e9/l
0.19
66
539
9
48
1.92
1.02
1.1
1.1
—
—
—
0
0
107
1189
0.76
1.00
7.8
7.0
41.3
41.8
mmol/mol
0.24
94
1091
5
23
2.21
0.98
4.2
1.4
—
—
—
0
0
24
167
1.50
0.98
1.6
1.8
—
—
—
0
0
17
109
1.62
0.97
2.4
1.4
—
—
—
0
0
76
645
1.30
0.96
6.1
5.9
0.2
0.2
e9/l
0.02
65
561
0
32
0.00
0.96
0.0
1.4
—
—
—
0
0
22
155
1.48
0.86
6.2
4.1
—
—
—
0
0
26
347
0.71
0.85
3.6
3.3
—
—
—
0
0
46
371
1.32
0.83
3.3
3.0
10723.3
7689.6
umol/l
0.11
39
305
136
1258
1.30
0.83
27.6
18.5
44.3
27.3
mg/l
4.99
130
1061
113
1232
0.79
0.81
5.2
5.2
6.0
6.2
mmol/l
1.07
97
1092
0
26
0.00
0.79
0.0
1.0
—
—
—
0
0
54
449
1.29
0.78
2.1
2.2
121.8
260.5
u/l
2.20
49
418
15
99
1.56
0.78
7.6
2.4
—
—
—
0
0
5
24
2.11
0.75
1.2
2.0
4.1
5.3
e9/l
—
5
24
5
24
2.11
0.75
1.6
2.3
—
—
—
0
0
11
68
1.66
0.73
6.2
4.2
—
—
—
0
0
5
25
2.03
0.73
1.2
2.6
64.6
61.8
%
—
5
25
33
259
1.33
0.72
29.8
29.2
1.5
1.4
inr
—
6
34
106
1156
0.81
0.71
3.7
4.3
1.2
1.3
mmol/l
0.02
93
1022
42
342
1.29
0.71
5.5
4.0
—
—
—
0
0
16
110
1.50
0.71
6.0
4.0
—
—
—
0
0
29
224
1.35
0.70
2.2
1.9
—
—
—
0
0
53
447
1.26
0.68
6.9
5.5
—
—
—
0
0
29
227
1.33
0.65
3.3
2.4
18.1
22.2
%
1.12
21
202
100
908
1.22
0.65
4.7
4.5
—
—
—
0
0
14
198
0.68
0.64
1.3
1.4
2.5
3.0
g/l
—
9
116
42
347
1.27
0.64
1.5
1.8
409.0
433.5
pmol/l
0.26
30
288
43
357
1.27
0.63
2.0
1.8
1087.1
1210.7
nmol/l
0.29
33
269
103
942
1.21
0.60
5.2
4.3
22.7
15.5
mm/h
2.13
89
853
81
725
1.21
0.59
4.3
5.5
2.3
3.3
ug/l
0.86
62
634
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
111
1192
0.83
0.57
4.2
4.8
1.3
1.4
mmol/l
0.80
100
1060
112
1201
0.83
0.57
4.3
4.8
4.2
4.3
mmol/l
0.77
99
1079
6
37
1.64
0.56
1.3
1.2
—
—
—
0
0
111
1029
1.20
0.54
31.7
20.2
35.9
38.4
%
1.38
64
635
14
102
1.40
0.49
2.6
1.5
—
—
—
0
0
117
1238
0.85
0.45
4.6
5.5
2.3
2.5
mmol/l
1.98
100
1101
46
401
1.20
0.44
2.2
2.1
2.6
3.2
mg/l
1.07
40
347
8
57
1.42
0.42
1.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
809.4
—
0
7
28
236
1.22
0.37
4.2
5.5
—
—
—
0
0
32
276
1.19
0.35
1.5
1.6
1.6
1.6
mg/l
0.06
27
221
6
86
0.69
0.34
1.3
1.5
—
—
—
0
0
50
450
1.15
0.33
4.4
4.7
—
—
—
0
0
5
73
0.68
0.26
1.0
1.3
—
—
—
0
0
14
170
0.81
0.26
1.3
1.3
14.7
37.3
iu/ml
—
7
64
68
636
1.11
0.24
3.9
4.5
31.9
45.0
ng/l
1.12
57
499
5
40
1.26
0.22
1.4
1.3
80.3
102.7
u/ml
—
5
34
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
499.2
—
0
6
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
109
1130
0.91
0.21
5.1
4.4
1.9
2.1
mu/l
0.87
99
985
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
135
1313
1.10
0.20
37.6
22.3
118.1
88.2
umol/l
9.50
135
1313
6
50
1.21
0.20
4.5
5.3
—
—
—
0
0
14
118
1.20
0.19
2.2
1.7
—
—
—
0
0
7
60
1.17
0.18
1.1
1.3
—
31.8
—
0
5
38
409
0.91
0.16
3.3
3.2
0.9
0.9
ug/l
0.04
21
281
8
99
0.80
0.14
1.1
1.6
—
—
—
0
0
130
1273
1.07
0.13
29.6
17.5
—
—
—
0
0
54
514
1.07
0.13
3.6
2.7
248.1
155.3
ug/l
1.16
48
460
32
298
1.09
0.12
7.3
4.1
—
—
—
0
0
134
1315
1.07
0.12
13.7
11.4
21.6
24.3
u/l
1.53
129
1258
91
889
1.05
0.08
4.0
3.5
15.3
15.1
pmol/l
0.32
78
773
7
80
0.87
0.07
4.3
4.4
—
—
—
0
0
16
149
1.08
0.05
1.8
1.5
—
—
—
0
0
17
159
1.08
0.05
3.5
2.5
6.9
11.2
umol/l
0.75
17
134
10
93
1.08
0.02
1.6
1.4
—
—
—
0
0
11
103
1.07
0.02
5.8
2.3
11.7
10.1
g/l
0.43
11
90
136
1354
1.02
0.00
41.5
26.9
4.1
4.4
e12/l
6.94
131
1297
10
101
0.99
0.00
1.8
2.1
8.6
12.1
nmol/l
—
10
91
62
621
1.00
0.00
2.3
2.1
91.3
92.8
pmol/l
0.13
34
329
55
548
1.01
0.00
13.5
10.8
0.0
0.0
e9/l
0.51
46
442
16
155
1.04
0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.2
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
7.3
—
44.4
—
0
7
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
3.2
—
1.1
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
22.4
—
0
6
0
5
0.00
0.00
0.0
2.2
—
2730.0
—
0
5
6
65
0.92
0.00
1.3
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_RENAL_PELVIS – Malignant neoplasm of renal pelvis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).