No definition available.
Venous complications and haemorrhoids in pregnancy
EFO MESH Endpoint Browser PheWeb
O15_PREG_VENOUS_HAEMORRH
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
710 |
4. Check minimum number of eventsNone |
710 |
5. Include endpointsNone |
710 |
6. Filter based on genotype QC (FinnGen only) |
710 |
Control definitions (FinnGen only)
- Control exclude
- O15_PREG_OTHER_MAT_DISORD
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- O20-O29
- Name in latin
- Complicationes venosae in graviditate
Similar endpoints
↥List of similar endpoints to
Venous complications and haemorrhoids in pregnancy
based on the number of shared cases.
Similar with more cases:
- Other maternal disorders predominantly related to pregnancy
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4663 | 4663 | - |
| Only index persons | 4618 | 4618 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.13 | - |
| Only index persons | 0.17 | 0.17 | - |
| Median age at first event (years) | |||
| Whole population | - | 32.12 | - |
| Only index persons | - | 32.09 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 710 | 710 | - |
| Unadjusted period prevalence (%) | 0.24 | 0.24 | - |
| Median age at first event (years) | 32.34 | 32.34 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 641
- Matched controls
- 6409
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O22.3
ICD-10 Finland
Deep phlebothrombosis in pregnancy
2384.8
184.7
170
*
O22.0
ICD-10 Finland
Varicose veins of lower extremity in pregnancy
2025.7
165.0
153
*
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
122.8
150.3
158
17
B01AB05
ATC
enoxaparin; parenteral
8.4
123.8
354
823
O22.2
ICD-10 Finland
Superficial thrombophlebitis in pregnancy
+∞
117.4
109
*
B01AA03
ATC
warfarin; systemic
16.7
99.1
166
131
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
7.5
93.4
264
550
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
11.1
89.2
184
225
O22.4
ICD-10 Finland
Haemorrhoids in pregnancy
91.5
79.4
87
11
O22.1
ICD-10 Finland
Genital varices in pregnancy
+∞
76.6
72
*
B01AB04
ATC
dalteparin; parenteral
18.2
72.2
115
76
O22.8
ICD-10 Finland
Other venous complications in pregnancy
+∞
60.4
57
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
4.2
58.6
308
1160
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
7.0
51.9
140
247
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
16.2
50.9
84
59
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
13.6
47.4
84
70
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
3.4
46.5
396
2079
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.5
44.9
297
1277
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
5.8
43.9
137
288
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
15.3
38.8
65
47
O20.0
ICD-10 Finland
Threatened abortion
76.5
38.4
43
6
PHD99
NOMESCO Finland
Resection of other vein
6.9
37.2
98
163
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
3.9
37.1
176
561
Z39.2
ICD-10 Finland
Routine postpartum follow-up
3.3
36.9
247
1035
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.9
36.0
420
2530
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
3.8
34.2
166
535
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
22.0
32.2
47
23
SPAT1197
SPAT
Extensive health check-up of expecting family
3.0
32.2
234
1017
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.4
31.8
185
685
SPAT1380
SPAT
Postpartum check-up
3.3
30.3
179
665
W78
ICPC
Pregnancy
2.8
29.8
251
1185
SPAT1379
SPAT
Health check-up of pregnant person
3.1
29.6
196
789
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
8.1
29.3
68
93
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.8
29.2
254
1220
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
16.8
27.6
44
28
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
8.2
26.7
61
81
W85
ICPC
Gestational diabetes
12.0
26.6
49
44
O22.9
ICD-10 Finland
Venous complication in pregnancy, unspecified
+∞
26.2
25
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
3.0
26.0
181
743
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
10.1
25.0
50
53
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
259.7
24.8
25
*
W84
ICPC
Pregnancy high risk
5.7
24.8
74
143
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
5.8
24.8
73
139
PHD76
NOMESCO Finland
Resection of long saphenous vein
6.5
24.6
66
111
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
21.7
24.1
35
17
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
248.9
23.8
24
*
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
129.9
23.8
25
*
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
+∞
23.1
22
*
O02.1
ICD-10 Finland
Missed abortion
3.7
22.0
105
324
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.7
21.2
170
753
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
10.4
20.9
41
42
SPAT1196
SPAT
Monitoring of normal pregnancy
3.0
20.8
135
521
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
216.8
20.7
21
*
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
43.2
20.6
25
6
D68.8
ICD-10 Finland
Other specified coagulation defects
12.2
20.5
37
32
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
+∞
19.9
19
*
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.8
19.8
146
610
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
3.4
19.3
103
346
O99.80
ICD-10 Finland
The fear of childbirth
3.6
19.1
92
285
M79.6
ICD-10 Finland
Pain in limb
2.2
18.8
258
1492
WX234
NOMESCO Finland
Paracervical blockade
4.5
18.4
68
166
O80.8
ICD-10 Finland
Other single spontaneous delivery
4.0
18.3
77
213
XMA22
NOMESCO Finland
General examination of pregnant woman
3.1
18.2
108
391
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
14.2
17.9
30
22
I80.9
ICD-10 Finland
Phlebitis and thrombophlebitis of unspecified site
18.0
17.1
26
15
MAX99
NOMESCO Finland
Assistance to normal delivery
2.4
16.8
168
826
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
3.3
16.8
90
302
PHM99
NOMESCO Finland
Endovenous obliteration of other vein
7.6
16.7
39
54
SPAT1357
SPAT
Monitoring of problem during pregnancy
4.8
16.4
55
122
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.5
16.0
145
674
6715A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other phlebitis and thrombosis[PHLEBITIS/THROMBOSIS ALIA,RASKAUDEN AIKANA]
+∞
15.7
15
*
6714A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Deep phlebothrombosis, postpartum[THROMBOPHLEB PROF EXTR INFER,RASKAUDEN AIKANA]
+∞
15.7
15
*
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
12.2
15.2
27
23
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
11.2
15.1
28
26
6712A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Superficial thrombophlebitis[THROMBOPHLEB SUPERFIC EXTR INF,RASKAUDEN AIKANA]
+∞
14.6
14
*
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
13.0
14.5
25
20
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
6.4
14.1
37
61
B01AB01
ATC
heparin; parenteral
+∞
13.6
13
*
Z86.7
ICD-10 Finland
Personal history of diseases of the circulatory system
+∞
13.6
13
*
I80.20
ICD-10 Finland
Phlebitis and thrombophlebitis in the iliac vein
34.9
13.6
17
5
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
16.6
13.5
21
13
K94
ICPC
Phlebitis/thrombophlebitis
12.5
13.2
23
19
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
4.4
13.1
47
112
R51.80
ICD-10 Finland
Headache
2.3
13.1
138
687
WX320
NOMESCO Finland
Spinalanesthesy
2.3
13.0
133
652
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
11.9
12.9
23
20
B01AF01
ATC
rivaroxaban; oral
5.0
12.6
40
84
K95
ICPC
Varicose veins of leg
9.6
12.6
25
27
W29
ICPC
Pregnancy symptom/complaint other
4.1
12.5
49
127
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
+∞
12.5
12
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.6
12.4
98
418
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
7.7
12.3
28
38
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
12.3
306
2128
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
12.3
223
1387
MAC96
NOMESCO Finland
Other induction or advancement of labour
3.7
12.1
53
152
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
3.0
12.0
72
258
TPH10
NOMESCO Finland
Sclerotherapy of varicose veins
16.8
11.7
18
11
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
3.7
11.7
51
146
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
11.6
264
1771
6718A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other venous complications[HAEMORRHOIDES ANI,RASKAUDEN AIKANA]
+∞
11.5
11
*
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
3.0
11.5
67
239
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
122.1
11.5
12
*
O32.1
ICD-10 Finland
Maternal care for breech presentation
2.9
11.3
72
270
W90
ICPC
Uncompl labour/delivery livebirth
2.8
11.1
73
281
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
11.0
499
4157
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
5.1
11.0
34
70
I80
ICD-10 Finland
Phlebitis and thrombophlebitis
12.2
10.9
19
16
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
2.0
10.9
157
889
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.2
10.8
123
628
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.9
10.5
66
247
PH6GT
NOMESCO Finland
Endovascular embolisation of ovarian vein with radiological guidance
111.8
10.4
11
*
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
+∞
10.4
10
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
3.4
10.4
50
155
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
4.3
10.3
37
89
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.7
10.2
34
76
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
10.2
290
2063
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
8.1
10.2
22
28
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
9.8
343
2584
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
9.6
268
1888
MAA00
NOMESCO Finland
Amniocentesis
4.5
9.5
33
77
O28.0
ICD-10 Finland
Abnormal haematological finding on antenatal screening of mother
+∞
9.4
9
*
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
2.7
9.1
61
238
N02BE01
ATC
paracetamol; systemic, rectal
1.9
8.9
526
4562
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
3.1
8.9
47
158
SPAT1263
SPAT
Sampling
1.7
8.8
271
1948
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.8
8.7
178
1132
PHM79
NOMESCO Finland
Endovenous obliteration of v.saphena anterior
11.8
8.6
15
13
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
6.1
8.5
22
37
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
5.8
8.5
23
41
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
91.2
8.4
9
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.7
8.4
206
1382
K02.1
ICD-10 Finland
Caries of dentine
1.6
8.3
401
3235
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.1
8.2
97
502
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
8.3
8.1
17
21
W05
ICPC
Pregnancy vomiting/nausea
7.0
8.1
19
28
D68.9
ICD-10 Finland
Coagulation defect, unspecified
17.4
8.1
12
7
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
3.8
8.1
33
91
G43.9
ICD-10 Finland
Migraine, unspecified
2.4
8.0
70
316
J01DA01
ATC
[U] cefalexin; systemic
1.6
8.0
408
3323
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
3.5
7.8
35
105
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
2.9
7.7
46
168
Z34
ICD-10 Finland
Supervision of normal pregnancy
2.3
7.6
72
337
D68.2
ICD-10 Finland
Hereditary deficiency of other clotting factors
25.3
7.6
10
*
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.9
7.6
115
657
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.6
7.6
356
2822
E66.9
ICD-10 Finland
Obesity, unspecified
3.9
7.5
29
76
WX110
NOMESCO Finland
Local anesthesy
1.6
7.5
452
3813
PH2AE
SPAT
NA
6.1
7.4
19
32
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
7.8
7.4
16
21
R3110
NOMESCO Finland
Psychosocial training
3.8
7.3
29
78
Z39.1
ICD-10 Finland
Care and examination of lactating mother
3.5
7.3
32
94
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
7.3
65
297
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
20.3
7.1
10
5
I83
ICD-10 Finland
Varicose veins of lower extremities
4.2
7.1
25
61
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.3
7.0
63
288
4549X
ICD-9 Finland
Varicose veins of lower extremities, Without mention of ulcer or inflammation
5.0
7.0
21
43
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
6.9
207
1451
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.3
6.9
32
99
KMAK
NOMESCO Finland
NA
1.6
6.9
395
3252
SPAT1301
SPAT
No procedures
1.7
6.9
165
1092
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.6
6.8
29
84
4538X
ICD-9 Finland
Other venous embolism and thrombosis, Of other specified veins
40.5
6.8
8
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
4.0
6.7
25
64
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
6.7
455
3884
L03
ICPC
Low back symptom/complaint
1.7
6.7
152
988
SPAT1310
SPAT
Counselling related to known health issue
1.7
6.7
177
1202
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
3.4
6.5
29
87
P01AB01
ATC
metronidazole; oral, rectal
1.6
6.5
264
1992
B01AB10
ATC
tinzaparin; parenteral
2.8
6.5
39
144
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.1
6.5
73
369
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.1
6.5
33
110
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
7.5
6.4
14
19
I87.0
ICD-10 Finland
Postthrombotic syndrome
70.5
6.4
7
*
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
6.4
357
2894
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.5
6.4
403
3361
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.3
335
2684
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
6.3
95
541
PHB76
NOMESCO Finland
Ligature of long saphenous vein
18.2
6.3
9
5
6489X
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Other current conditions classifiable elsewhere
+∞
6.3
6
*
O28.1
ICD-10 Finland
Abnormal biochemical finding on antenatal screening of mother
+∞
6.3
6
*
A02BC01
ATC
omeprazole; systemic
1.7
6.2
130
822
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
4.6
6.2
20
45
O72.0
ICD-10 Finland
Third-stage haemorrhage
3.0
6.2
33
114
5611
FHL
Vena saphena Magna and / or swarm of nodule and possible local emissions
4.7
6.1
19
41
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
4.7
6.1
19
41
MBA04
NOMESCO Finland
Curettage of uterus after delivery
8.7
6.1
12
14
WX290
NOMESCO Finland
Other blockade of nerve
1.5
6.1
330
2651
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
5.6
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
287
1368
2.84
38.50
2.2
1.7
0.8
0.7
mg/l
0.53
223
996
115
384
3.38
28.03
1.7
1.5
—
—
—
0
0
177
861
2.41
20.78
1.6
1.5
—
—
—
0
0
67
190
3.79
20.75
1.7
2.3
103.4
95.9
%
1.62
55
170
129
554
2.62
19.66
1.7
1.4
—
—
—
0
0
385
2644
2.00
17.93
4.5
3.7
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
32
56
5.94
17.72
4.7
5.7
0.4
0.4
u/ml
0.01
23
27
48
126
4.01
16.53
1.1
1.1
117.7
115.1
%
0.22
43
115
48
130
3.89
15.84
1.1
1.1
—
—
—
0
0
48
134
3.77
15.17
2.6
1.6
4.4
3.9
umol/l
0.39
34
103
54
165
3.46
14.94
2.2
2.8
149.0
155.5
%
0.31
47
156
80
318
2.71
14.05
1.8
1.6
—
—
—
0
0
71
267
2.84
13.84
1.6
1.4
—
—
—
0
0
78
314
2.67
13.35
28.7
10.7
1.3
1.1
inr
0.94
15
63
480
3761
1.85
12.94
4.7
3.3
99.5
622.9
e6/l
0.93
11
37
37
97
3.97
12.77
2.0
1.5
8.0
6.9
mmol/l
1.01
18
51
42
128
3.42
11.67
1.2
1.3
2.6
6.9
u/ml
1.29
17
50
356
2605
1.74
11.60
3.9
3.8
6.0
6.0
mmol/l
0.23
310
2348
23
46
5.13
11.06
1.0
1.0
89.5
84.1
%
0.27
18
40
39
122
3.32
10.42
1.3
1.3
3.2
5.9
u/ml
0.49
11
40
25
65
3.95
8.75
1.1
1.1
1.0
1.0
ratio
—
9
26
95
512
1.99
8.13
2.0
2.1
29.0
29.4
s
0.35
90
490
178
1183
1.67
7.62
1.3
1.3
5.9
9.8
u/ml
0.62
72
543
624
5613
1.92
7.53
9.6
8.4
3.9
3.9
mmol/l
0.05
608
5451
112
654
1.85
7.52
2.6
2.0
7577.2
4565.8
u/l
0.48
47
238
621
5592
1.88
7.26
9.5
8.3
139.7
139.5
mmol/l
2.35
606
5446
208
1455
1.61
7.21
2.5
2.3
52.2
55.0
u/l
0.86
198
1366
171
1158
1.63
6.71
3.5
3.0
1.0
1.0
kg/l
0.09
27
159
93
533
1.86
6.61
1.6
1.4
—
—
—
0
0
85
492
1.83
5.85
1.5
1.4
—
—
—
0
0
85
493
1.82
5.81
1.5
1.4
—
—
—
0
0
85
494
1.82
5.77
1.5
1.4
—
—
—
0
0
256
1955
1.48
5.72
1.9
1.6
—
—
—
0
0
305
2413
1.46
5.68
5.9
5.1
9.7
9.4
umol/l
0.18
285
2273
84
490
1.81
5.64
1.5
1.4
—
—
—
0
0
456
3905
1.47
5.54
7.1
6.3
70.1
70.5
u/l
0.06
436
3701
29
112
2.66
5.45
1.4
1.5
—
—
—
0
0
170
1202
1.54
5.44
1.9
1.9
—
—
—
0
0
77
447
1.81
5.25
4.4
4.3
—
—
—
0
0
348
2858
1.43
5.14
3.3
2.9
0.0
0.0
estimate
0.50
58
540
646
6012
1.83
5.10
11.4
9.3
15.5
18.2
mg/l
1.87
512
4476
106
681
1.65
5.05
2.1
2.7
22.3
339.0
ng/l
1.29
41
297
174
1260
1.50
4.94
1.3
1.3
17.4
20.6
iu/ml
0.32
50
428
176
1279
1.50
4.91
2.2
2.1
2.3
2.6
mg/l
1.56
156
1094
485
4262
1.44
4.71
3.9
3.7
8.2
8.7
mm/h
0.65
455
4044
22
83
2.70
4.36
1.4
1.2
—
—
—
0
0
214
1658
1.42
4.19
1.3
1.3
1.2
1.3
u/ml
0.10
55
471
412
3565
1.37
4.08
3.2
2.8
61.0
59.8
ug/l
0.07
390
3403
91
594
1.61
4.07
1.7
1.7
—
—
—
0
0
231
1824
1.39
4.03
4.3
4.1
36.5
37.3
g/l
1.55
218
1697
339
2855
1.36
3.93
4.6
4.0
0.0
0.0
estimate
0.42
60
558
77
488
1.65
3.87
2.5
2.7
33.1
33.0
%
0.01
62
374
341
2889
1.35
3.74
3.4
2.9
0.0
0.0
estimate
1.06
59
553
180
1396
1.39
3.42
2.3
2.3
8.8
15.6
ng/l
2.38
63
498
145
1092
1.41
3.26
1.9
1.9
290.0
2338.8
umol/l
2.01
136
1007
96
669
1.50
3.23
2.3
2.1
0.5
0.9
e6/l
2.07
51
343
31
159
1.99
3.14
2.4
1.9
—
—
—
0
0
248
2065
1.31
2.88
5.0
5.3
1.2
1.2
mmol/l
0.37
215
1745
701
6865
2.67
2.85
17.2
14.0
132.6
133.4
g/l
1.38
694
6811
16
66
2.46
2.72
3.7
1.5
—
—
—
0
0
33
183
1.84
2.70
2.3
2.0
—
—
—
0
0
52
330
1.62
2.66
1.3
1.4
0.3
1.5
u/ml
—
5
28
147
1154
1.35
2.54
1.8
1.8
—
—
—
0
0
44
271
1.66
2.53
1.7
1.8
—
—
—
0
0
71
493
1.49
2.46
1.4
1.5
—
—
—
0
0
218
1816
1.29
2.46
4.4
4.8
1.2
1.2
mmol/l
0.22
201
1678
11
40
2.78
2.38
1.3
1.3
—
—
—
0
0
5
8
6.28
2.37
1.6
1.4
—
—
—
0
0
177
1450
1.29
2.25
4.0
3.2
0.0
0.0
estimate
1.34
56
556
25
135
1.88
2.25
1.1
1.1
5.3
11.2
au/ml
—
5
10
85
626
1.41
2.18
2.4
2.3
3.9
5.2
e6/l
0.48
42
303
650
6251
1.47
2.18
9.1
7.8
23.6
22.9
u/l
0.44
634
6099
35
212
1.68
2.17
1.4
1.1
—
—
—
0
0
226
1918
1.26
2.16
4.1
3.0
27.4
26.7
u/l
0.11
219
1834
607
5774
1.35
2.14
5.4
4.9
1.6
1.9
mu/l
0.98
575
5579
16
75
2.16
2.10
1.4
1.2
—
—
—
0
0
55
376
1.50
2.08
1.3
1.5
—
—
—
0
0
262
2274
1.24
2.03
3.6
2.8
—
—
—
0
0
70
506
1.43
2.01
1.5
1.8
—
—
—
0
0
53
364
1.49
1.97
1.3
1.5
—
—
—
0
0
548
5161
1.27
1.94
4.8
4.3
14.3
14.1
pmol/l
1.20
518
4925
10
39
2.59
1.92
1.1
1.2
—
—
—
0
0
20
106
1.91
1.92
1.4
1.3
101.9
107.4
u/ml
—
6
22
18
93
1.96
1.86
1.2
1.6
—
—
—
0
0
5
12
4.19
1.82
1.2
1.1
—
—
—
0
0
12
53
2.29
1.81
1.0
1.0
—
—
—
0
0
43
291
1.51
1.74
6.3
9.5
0.3
0.9
mmol/l
0.69
28
207
240
2094
1.22
1.73
1.6
1.5
—
—
—
0
0
5
13
3.86
1.71
1.4
1.5
—
—
—
0
0
5
13
3.86
1.71
1.4
1.5
—
—
—
0
0
7
26
2.71
1.58
4.1
2.4
—
—
—
0
0
112
906
1.28
1.57
1.6
1.7
—
—
—
0
0
27
168
1.63
1.57
1.4
1.4
—
—
—
0
0
29
185
1.59
1.53
1.2
1.2
—
—
—
0
0
144
1205
1.24
1.53
2.9
2.4
0.2
0.3
e6/l
0.66
98
878
116
950
1.26
1.48
1.5
1.4
19.8
20.6
nmol/l
0.23
106
867
17
94
1.83
1.48
1.9
1.3
6.2
7.2
mmol/l
—
9
65
363
3333
1.18
1.44
7.2
8.5
3.8
4.0
e9/l
1.11
331
2981
80
630
1.30
1.39
1.7
2.7
385.1
431.9
ng/l
0.08
57
518
9
41
2.21
1.37
1.7
1.7
—
—
—
0
0
51
376
1.38
1.37
2.1
2.1
80.7
84.1
ml/min/173m2
0.36
23
148
28
184
1.54
1.33
1.1
1.2
—
—
—
0
0
35
242
1.47
1.32
1.9
2.2
—
—
—
0
0
8
34
2.37
1.29
1.6
1.8
—
—
—
0
0
11
55
2.02
1.28
4.4
2.4
15.1
37.9
u/ml
0.53
11
55
16
92
1.76
1.26
1.9
1.5
—
—
—
0
0
198
1745
1.19
1.24
1.8
1.7
101.3
99.7
pmol/l
0.15
104
1005
581
5591
1.22
1.22
4.5
3.8
—
—
—
0
0
8
40
2.01
1.12
1.6
1.3
—
—
—
0
0
16
96
1.68
1.11
1.2
1.5
—
—
—
0
0
32
227
1.43
1.09
1.7
1.6
—
—
—
0
0
5
21
2.39
1.09
1.0
2.1
—
—
—
0
0
5
21
2.39
1.09
1.0
2.1
—
—
—
0
0
5
21
2.39
1.09
1.0
2.1
—
—
—
0
0
5
21
2.39
1.09
1.0
2.1
—
—
—
0
0
68
545
1.27
1.07
3.3
2.4
5.4
4.9
umol/l
0.21
53
445
140
1213
1.19
1.06
1.5
1.6
1.3
1.3
mmol/l
0.15
119
1088
559
5381
1.18
1.06
3.4
3.1
5.5
5.5
mmol/l
0.28
532
5136
183
1627
1.17
1.03
2.7
3.0
2.3
2.3
mmol/l
1.06
166
1493
7
35
2.01
1.00
1.0
1.7
—
—
—
0
0
7
35
2.01
1.00
1.0
1.7
—
—
—
0
0
7
35
2.01
1.00
1.0
1.7
—
—
—
0
0
7
35
2.01
1.00
1.4
3.0
236.0
656.5
u/ml
—
7
35
11
61
1.82
0.99
1.2
1.6
—
—
—
0
0
37
489
0.74
0.98
1.4
1.4
—
—
—
0
0
90
754
1.22
0.98
2.8
2.1
2.4
2.4
mmol/l
0.14
74
648
11
62
1.79
0.94
1.2
1.7
—
—
—
0
0
191
1717
1.15
0.93
2.3
2.1
—
—
—
0
0
30
218
1.39
0.93
1.5
1.4
1.7
8.8
u/ml
—
5
44
28
380
0.73
0.89
1.4
1.7
2.1
3.4
mg/l
1.01
16
240
20
287
0.69
0.87
1.2
1.3
—
—
—
0
0
32
238
1.36
0.87
1.2
1.3
—
—
—
0
0
20
136
1.48
0.87
1.6
1.8
—
—
—
0
0
92
783
1.20
0.87
3.9
3.8
20.1
13.8
mg/mmol
0.29
53
503
556
5378
1.16
0.86
8.3
7.4
95.4
94.3
ml/min/173m2
0.82
461
4367
20
137
1.47
0.85
1.3
1.2
—
—
—
0
0
74
619
1.22
0.84
1.6
1.6
1059.6
1192.7
nmol/l
0.88
62
490
170
1529
1.15
0.82
2.1
2.0
—
—
—
0
0
72
852
0.83
0.79
1.2
1.3
22.8
26.2
iu/l
0.46
63
730
34
261
1.32
0.78
2.8
3.1
1.5
1.9
mmol/l
0.64
27
210
9
53
1.71
0.75
1.2
1.4
—
—
—
0
0
5
24
2.09
0.74
2.4
2.0
1.7
1.4
nmol/l
—
5
24
19
134
1.43
0.72
7.6
11.3
95.5
94.2
%
1.11
19
134
55
455
1.23
0.71
1.0
1.0
—
—
—
0
0
33
257
1.30
0.70
1.6
1.6
—
—
—
0
0
22
162
1.37
0.67
1.5
1.4
—
1.5
—
0
14
32
250
1.29
0.67
1.4
2.3
39.4
40.7
u/l
0.14
32
232
7
44
1.60
0.65
1.1
1.0
—
—
—
0
0
32
252
1.28
0.63
5.7
6.5
1.1
1.2
mmol/l
0.27
32
239
8
49
1.64
0.62
2.7
1.6
—
—
—
0
0
8
50
1.61
0.61
2.7
1.6
—
—
—
0
0
8
50
1.61
0.61
2.7
1.6
—
—
—
0
0
8
50
1.61
0.61
2.8
1.6
—
—
—
0
0
8
50
1.61
0.61
2.8
1.6
—
—
—
0
0
8
50
1.61
0.61
2.7
1.6
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
8
52
1.54
0.59
1.4
1.3
—
—
—
0
0
31
246
1.27
0.59
1.5
1.9
0.2
0.2
g/l
0.11
31
232
32
256
1.26
0.57
1.5
1.8
1.1
1.2
g/l
1.36
32
241
8
54
1.49
0.57
1.3
1.4
12.2
9.8
umol/l
—
8
47
582
5692
1.12
0.57
3.3
3.1
4.8
4.9
mmol/l
0.36
552
5499
6
36
1.67
0.56
1.3
1.4
5.2
5.1
mmol/l
—
6
36
55
468
1.19
0.56
1.4
1.5
—
—
—
0
0
11
73
1.51
0.56
1.0
1.1
—
—
—
0
0
6
38
1.58
0.54
1.3
1.5
—
—
—
0
0
79
893
0.87
0.54
2.0
1.7
1.4
1.3
%
0.29
69
810
6
39
1.54
0.53
1.2
3.6
0.2
0.2
e9/l
—
6
34
579
5670
1.11
0.51
3.3
3.1
1.5
1.6
mmol/l
3.51
548
5472
27
215
1.27
0.51
1.1
1.2
—
—
—
0
0
551
5385
1.10
0.50
12.5
11.2
13.5
13.5
%
0.01
544
5288
18
232
0.77
0.46
1.1
1.1
0.2
1.2
u/ml
—
8
88
56
490
1.16
0.44
2.3
2.2
19.0
21.6
au/ml
—
6
41
485
4726
1.08
0.43
4.0
3.4
36.9
36.4
mmol/mol
1.03
458
4533
5
31
1.62
0.43
1.4
1.1
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
48
550
0.86
0.41
1.7
1.6
318.5
314.9
mu/l
0.02
40
492
556
5453
1.09
0.41
3.0
2.9
1.1
1.1
mmol/l
0.14
527
5257
0
16
0.00
0.41
0.0
2.8
—
31.8
—
0
16
0
17
0.00
0.40
0.0
1.6
—
—
—
0
0
17
132
1.29
0.40
1.2
1.3
—
—
—
0
0
53
466
1.15
0.40
2.0
2.2
42.4
36.4
u/l
0.16
43
380
13
97
1.35
0.39
4.4
3.1
17.3
23.5
mg/l
—
7
65
0
19
0.00
0.39
0.0
2.1
—
2.1
—
0
12
11
80
1.38
0.38
1.5
1.9
10384.3
6228.0
e6/l
—
6
64
9
69
1.31
0.37
1.2
1.2
—
—
—
0
0
9
69
1.31
0.37
1.2
1.2
—
—
—
0
0
9
69
1.31
0.37
1.2
1.2
—
—
—
0
0
48
422
1.15
0.37
3.8
5.2
1.0
1.0
mmol/l
0.03
48
393
9
124
0.72
0.35
1.0
1.3
3.8
3.5
mmol/l
—
9
111
19
154
1.24
0.34
1.1
1.0
1.2
2.2
u/ml
—
9
88
19
154
1.24
0.34
1.9
2.4
8.2
10.2
mg/l
0.80
19
145
582
5734
1.08
0.33
3.4
3.2
3.0
2.9
mmol/l
0.53
547
5506
6
46
1.31
0.33
1.3
1.4
—
—
—
0
0
6
47
1.28
0.32
1.0
1.1
—
—
—
0
0
11
84
1.31
0.30
1.1
1.3
—
—
—
0
0
7
55
1.28
0.30
1.4
1.4
—
—
—
0
0
7
56
1.25
0.29
1.3
2.1
—
—
—
0
0
10
76
1.32
0.28
1.2
1.2
—
—
—
0
0
10
76
1.32
0.28
1.2
1.2
—
—
—
0
0
98
918
1.08
0.26
1.5
1.5
442.6
45650005.9
pmol/l
1.13
90
839
8
67
1.20
0.26
1.3
1.3
—
—
—
0
0
78
724
1.09
0.26
1.4
1.2
118.2
153.7
iu/ml
0.37
36
289
5
74
0.67
0.26
1.2
1.2
—
—
—
0
0
5
75
0.66
0.26
1.4
2.7
—
—
—
0
0
252
2438
1.05
0.25
2.6
2.2
73.5
74.0
nmol/l
0.12
239
2313
451
4427
1.05
0.25
3.1
2.7
30.1
31.2
u/l
0.24
442
4289
17
142
1.20
0.25
1.2
1.2
—
—
—
0
0
11
87
1.27
0.24
5.5
4.4
22.0
120.9
u/ml
—
5
29
16
133
1.21
0.24
1.3
1.2
185.8
246.4
u/ml
—
10
81
5
39
1.28
0.23
1.6
1.1
90.4
151.3
iu/ml
—
5
39
5
40
1.25
0.22
1.4
1.4
5.0
6.8
u/l
—
5
34
5
41
1.22
0.22
1.4
1.2
0.3
0.3
g/l
—
5
34
24
210
1.15
0.22
1.2
1.3
—
28.5
—
0
22
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
16
136
1.18
0.20
1.4
1.4
314.5
327.2
ug/g
0.07
11
75
31
280
1.11
0.18
2.5
1.8
—
—
—
0
0
11
91
1.21
0.17
1.0
1.4
—
—
—
0
0
20
176
1.14
0.17
1.4
2.5
0.9
1.1
mmol/l
—
10
126
8
68
1.18
0.16
1.3
1.2
—
—
—
0
0
8
68
1.18
0.16
1.3
1.2
—
—
—
0
0
6
79
0.76
0.15
1.0
1.2
—
—
—
0
0
20
223
0.89
0.14
1.5
2.3
2.6
4.3
iu/l
—
6
104
45
422
1.07
0.13
1.2
1.3
346.4
232.0
miu/ml
1.03
26
227
31
286
1.09
0.13
3.6
3.8
2.8
133.2
ug/l
0.52
20
205
66
628
1.06
0.13
1.9
2.1
2.4
2.5
g/l
0.67
60
591
15
132
1.14
0.13
1.0
1.1
—
—
—
0
0
20
180
1.11
0.13
1.4
2.6
4.8
5.1
kpa
0.91
20
169
73
699
1.05
0.12
1.9
2.1
15.1
15.0
umol/l
0.02
67
649
27
249
1.09
0.12
4.9
8.1
5.2
6.5
mmol/l
1.26
27
241
10
116
0.86
0.12
1.6
4.0
59.0
57.2
%
—
10
116
33
308
1.07
0.11
1.9
2.8
1.2
1.2
mmol/l
0.05
27
276
10
114
0.88
0.09
1.6
3.7
4.2
4.2
e9/l
—
10
114
13
116
1.12
0.09
1.7
3.2
54.4
51.3
%
0.20
13
116
7
65
1.08
0.08
2.0
1.7
—
—
—
0
0
6
72
0.83
0.07
1.0
1.1
—
—
—
0
0
13
119
1.09
0.06
1.2
2.5
23.7
24.5
mmol/l
0.67
13
112
12
131
0.91
0.05
9.6
10.3
24.0
23.7
mmol/l
0.15
12
125
86
878
0.98
0.05
1.4
1.5
—
—
—
0
0
10
92
1.09
0.03
3.0
6.2
394.0
380.8
umol/l
—
10
76
13
138
0.94
0.02
1.0
1.1
—
—
—
0
0
10
107
0.93
0.02
2.7
1.7
—
—
—
0
0
30
308
0.97
0.02
2.0
1.9
—
—
—
0
0
604
6031
1.01
0.01
11.7
10.0
39.7
39.7
%
0.02
477
5183
55
556
0.99
0.00
2.0
2.2
26.1
24.1
%
0.40
46
483
54
537
1.01
0.00
1.3
1.3
66.5
147.4
u/ml
3.80
49
491
40
398
1.01
0.00
2.7
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1.3
—
0
5
0
5
0.00
0.00
0.0
1.6
—
5.1
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
2.6
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
69
0.87
0.00
1.2
1.1
1.5
1.5
g/l
—
6
63
6
65
0.92
0.00
2.0
2.4
23.1
24.1
mmol/l
—
6
59
5
55
0.91
0.00
1.4
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
9
97
0.93
0.00
1.2
1.3
27.5
36.0
nmol/l
—
9
85
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
5
54
0.93
0.00
1.0
1.4
1.1
0.9
g/l
—
5
54
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
53
0.94
0.00
1.0
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
1.2
—
0
7
6
66
0.91
0.00
1.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint O15_PREG_VENOUS_HAEMORRH and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have O15_PREG_VENOUS_HAEMORRH.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: O15_PREG_VENOUS_HAEMORRH – Venous complications and haemorrhoids in pregnancy
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data