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Other, unspecified and serous retinal detachments

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H7_RETINALDETACHOTH

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

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Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H33.2, H33.5
  • Hospital discharge: ICD-9 — 361[8-9]
  • Hospital discharge: ICD-8 — 376
  • Hospital discharge: excluded ICD-8 — 37602
  • Cause of death: ICD-10 — H33.2, H33.5
  • Cause of death: ICD-9 — 361[8-9]
  • Cause of death: ICD-8 — 376
  • Cause of death: excluded ICD-8 — 37602

2 out of 7 registries used, show all original rules.

1082

4. Check minimum number of events

None

1082

5. Include endpoints

None

1082

6. Filter based on genotype QC (FinnGen only)

1082

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9905 4592 5209
Only index persons 7811 3666 4145
Unadjusted period prevalence (%)
Whole population 0.14 0.13 0.15
Only index persons 0.15 0.13 0.16
Median age at first event (years)
Whole population 59.61 61.44 58.09
Only index persons 58.28 60.41 56.39

-FinnGen-

Key figures

All Female Male
Number of individuals 1082 490 592
Unadjusted period prevalence (%) 0.22 0.17 0.26
Median age at first event (years) 58.13 58.22 58.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
972
Matched controls
9718
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H33.0
ICD-10 Finland
Retinal detachment with retinal break
4450.6
323.0
441
*
H33.5
ICD-10 Finland
Other retinal detachments
1499.7
323.0
509
7
H33.2
ICD-10 Finland
Serous retinal detachment
1731.6
276.8
256
*
WX140
NOMESCO Finland
Parabulbar anesthesy
48.4
205.4
250
69
CKD40
NOMESCO Finland
Endophotocoagulation of retina
2212.5
185.5
174
*
CKC12
NOMESCO Finland
Photocoagulation of retina
310.6
180.3
178
7
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
2034.6
174.4
164
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
196.2
174.2
177
11
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
6.1
148.6
609
2090
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
1621.6
146.7
139
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
318.7
138.2
137
5
H33.3
ICD-10 Finland
Retinal breaks without detachment
1430.7
131.4
125
*
37600
ICD-8 Finland
Detachment of retina, Primaria
+∞
131.3
123
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
11.6
109.5
217
235
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.2
105.3
290
543
XCW99
NOMESCO Finland
Other investigative procedure of eye
8.7
103.3
245
364
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.3
92.9
485
1827
S01ED51
ATC
timolol, combinations; ophthalmic
8.3
90.0
217
325
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
85.7
81
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
84.6
80
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
45.0
82.0
101
25
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
80.3
76
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
78.2
74
*
H26.4
ICD-10 Finland
After-cataract
7.0
76.6
207
361
CJB10
NOMESCO Finland
Laser discission of secondary cataract
7.2
72.1
190
318
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
258.7
71.3
72
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
65.3
62
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
65.3
62
*
H43.8
ICD-10 Finland
Other disorders of vitreous body
6.0
64.8
196
391
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
173.8
62.8
65
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
+∞
58.9
56
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
57.9
55
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
77.1
57.8
65
9
37601
ICD-8 Finland
Detachment of retina, Secundaria
+∞
56.8
54
*
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
125.4
55.5
59
5
H26.2
ICD-10 Finland
Complicated cataract
38.9
54.6
69
19
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.1
54.6
246
740
S01ED01
ATC
timolol; ophthalmic
9.5
52.5
112
131
S01EC01
ATC
acetazolamide; systemic
16.5
52.1
85
56
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
524.0
50.9
50
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
44.0
47.1
58
14
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
103.1
45.2
49
5
H25.1
ICD-10 Finland
Senile nuclear cataract
2.9
43.3
339
1513
XCK10
NOMESCO Finland
Photography of fundus of eye
4.7
40.2
149
363
3745
FHL
Hard membrane girding, cerclage with coagulation
+∞
34.6
33
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
6.2
34.1
96
169
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
181.3
33.9
35
*
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
18.5
33.0
51
29
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
32.5
31
*
ZXA00
NOMESCO Finland
Right side
2.5
31.9
339
1741
3643
FHL
Vitrectomy through pars Plana
+∞
31.4
30
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
62.2
31.3
36
6
XCH00
NOMESCO Finland
Eye pressure measurement
6.7
30.8
81
130
114
Kela drug reimbursment
Glaucoma
3.7
30.8
148
453
H3603, E103
ICD-10 Finland
NA
+∞
30.4
29
*
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
29.3
28
*
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
8.3
28.8
65
83
3618X
ICD-9 Finland
Retinal detachments and defects, Other forms of retinal detachment
+∞
28.3
27
*
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
+∞
28.3
27
*
H26.02
ICD-10 Finland
Presenil cataract
8.5
27.0
60
75
H35.4
ICD-10 Finland
Peripheral retinal degeneration
143.9
26.7
28
*
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
26.2
25
*
37609
ICD-8 Finland
Detachment of retina, Unspecified
+∞
26.2
25
*
ZXA05
NOMESCO Finland
Left side
2.3
25.7
301
1590
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
25.3
422
2603
3619X
ICD-9 Finland
Retinal detachments and defects, Unspecified retinal detachment
+∞
25.1
24
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
+∞
25.1
24
*
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
25.1
24
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.0
25.0
157
579
S01EE01
ATC
latanoprost; ophthalmic
4.2
24.6
99
258
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
16.2
24.3
39
25
S01BC03
ATC
diclofenac; ophthalmic
8.9
23.3
50
59
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
23.0
22
*
WX002
NOMESCO Finland
Sedation and analgesia
2.3
22.8
242
1205
H34.8
ICD-10 Finland
Other retinal vascular occlusions
235.2
22.7
23
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
8.1
22.5
51
66
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
33.1
22.5
29
9
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
+∞
22.0
21
*
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
82.0
21.8
24
*
S01BC05
ATC
ketorolac; ophthalmic
5.1
21.7
70
145
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
44.4
21.5
26
6
S01EA03
ATC
apraclonidine; ophthalmic
15.1
21.3
35
24
CKC20
NOMESCO Finland
Cryopexy of undetached retina
+∞
20.9
20
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
+∞
20.9
20
*
H3603, E113
ICD-10 Finland
NA
+∞
20.9
20
*
3747
FHL
Combined ablation and vitreous surgery with coagulation
+∞
20.9
20
*
XCK00
NOMESCO Finland
Perimetry
3.6
20.3
95
282
37603
ICD-8 Finland
Detachment of retina, Retinoschisis
+∞
19.9
19
*
XCD20
NOMESCO Finland
Photoangiography of eye
41.0
19.6
24
6
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
13.6
19.3
33
25
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.5
19.0
69
163
H27.0
ICD-10 Finland
Aphakia
35.1
19.0
24
7
H3600, E113
ICD-10 Finland
NA
+∞
18.8
18
*
H54.4
ICD-10 Finland
Blindness, monocular
71.3
18.8
21
*
H52.1
ICD-10 Finland
Myopia
6.5
18.7
49
79
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
39.2
18.6
23
6
H40.0
ICD-10 Finland
Glaucoma suspect
3.3
18.6
97
314
S01EC04
ATC
brinzolamide; ophthalmic
4.9
18.3
61
132
A10AA01
ATC
NA
9.1
17.8
37
42
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
6.8
17.5
44
67
A10AA02
ATC
NA
6.6
17.5
45
71
H3601, E113
ICD-10 Finland
NA
+∞
16.7
16
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
16.7
105
386
H35.37
ICD-10 Finland
Macular holes
172.8
16.5
17
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
16.0
372
2478
H3601, E103
ICD-10 Finland
NA
+∞
15.7
15
*
S01FA01
ATC
atropine; ophthalmic
17.5
15.7
24
14
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
162.4
15.5
16
*
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
162.4
15.5
16
*
CKC15
NOMESCO Finland
Panretinal photocoagulation
162.4
15.5
16
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
12.6
15.4
27
22
37002
ICD-8 Finland
Refractive errors, Myopia
29.1
15.2
20
7
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.2
15.2
80
261
S01EC03
ATC
dorzolamide; ophthalmic
9.6
15.0
30
32
ZXD05
NOMESCO Finland
Urgent procedure
1.8
14.7
308
1966
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
14.6
14
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
36.6
14.5
18
5
H57.1
ICD-10 Finland
Ocular pain
4.9
14.4
47
100
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.0
13.7
83
297
37700
ICD-8 Finland
Other diseases of retina and optic nerve, Haemorrhagia corporis vitrei
+∞
13.6
13
*
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
18.5
13.4
20
11
H53.1
ICD-10 Finland
Subjective visual disturbances
3.0
13.1
77
271
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
5.9
13.1
36
63
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
70.8
12.6
14
*
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
32.5
12.6
16
5
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
32.5
12.6
16
5
H35.36
ICD-10 Finland
Macular cyst
+∞
12.5
12
*
CKD30
NOMESCO Finland
Internal drainage of subretinal fluid
+∞
12.5
12
*
T89
ICPC
Diabetes insulin dependent
4.8
12.2
40
86
H20.1
ICD-10 Finland
Chronic iridocyclitis
10.7
11.8
22
21
H25.8
ICD-10 Finland
Other senile cataract
2.3
11.8
115
540
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
11.7
241
1512
H33
ICD-10 Finland
Retinal detachments and breaks
+∞
11.5
11
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
11.5
11
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.1
11.3
43
108
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
43.8
10.9
13
*
H54.0
ICD-10 Finland
Blindness, binocular
43.8
10.9
13
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
43.8
10.9
13
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.3
10.8
25
35
S01EE05
ATC
tafluprost; ophthalmic
3.5
10.6
48
141
A10AE05
ATC
insulin detemir; parenteral
3.1
10.5
57
191
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
5.3
10.5
31
60
H36.01
ICD-10 Finland
Diabetic maculopathy
111.1
10.4
11
*
ZXA10
NOMESCO Finland
Bilateral
1.9
10.4
177
1039
H3600, E103
ICD-10 Finland
NA
+∞
10.4
10
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
10.4
10
*
3649
FHL
Other measure in this category
+∞
10.4
10
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.9
10.1
40
105
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
40.5
10.0
12
*
S01EE03
ATC
bimatoprost; ophthalmic
4.4
10.0
35
82
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
3.0
9.9
57
199
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
16.9
9.9
15
9
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
16.9
9.9
15
9
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
7.5
9.7
22
30
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.7
9.6
31
67
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
3.2
9.5
48
154
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
100.9
9.4
10
*
CKD25
NOMESCO Finland
External drainage of subretinal fluid
100.9
9.4
10
*
37403
ICD-8 Finland
Cataract, Complicata
100.9
9.4
10
*
ZXE00
NOMESCO Finland
One hour or less
1.6
9.4
348
2546
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
30.3
9.4
12
*
3759
FHL
Other measure in this category
+∞
9.4
9
*
S01EX03
ATC
NA
4.3
9.4
33
78
A10AE04
ATC
insulin glargine; parenteral
2.3
9.1
86
398
87011
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Complicata
37.0
9.0
11
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
8.8
83
385
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
50.4
8.7
10
*
37405
ICD-8 Finland
Cataract, Traumatica
50.4
8.7
10
*
H54.1
ICD-10 Finland
Severe visual impairment, binocular
27.8
8.5
11
*
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
+∞
8.3
8
*
CKC75
NOMESCO Finland
Removal of cerclage from sclera
+∞
8.3
8
*
CFB00
NOMESCO Finland
Suture of conjunctiva
+∞
8.3
8
*
37404
ICD-8 Finland
Cataract, Secundaria
+∞
8.3
8
*
H34.2
ICD-10 Finland
Other retinal artery occlusions
+∞
8.3
8
*
S01AX11
ATC
[U] ofloxacin; ophthalmic
3.1
8.3
43
141
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.7
8.3
56
215
3661A
ICD-9 Finland
Cataract, Senile cataract
4.9
8.1
25
52
37520
ICD-8 Finland
Glaucoma, Secondary
33.6
8.1
10
*
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
33.6
8.1
10
*
ZX198
NOMESCO Finland
Other local administration
11.8
8.1
14
12
ZYC01
NOMESCO Finland
Remote contact by phone
2.9
8.1
47
167
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.3
8.1
28
66
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
8.0
110
596
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
13.2
7.9
13
10
Z3231
NOMESCO Finland
Registered nurse
1.6
7.8
249
1742
CKA10
NOMESCO Finland
Biopsy of vitreous body
45.3
7.7
9
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
7.6
350
2660
S01EB01
ATC
pilocarpine; ophthalmic
8.1
7.6
16
20
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
25.2
7.6
10
*
87091
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Sequelae
80.7
7.4
8
*
H44.0
ICD-10 Finland
Purulent endophthalmitis
80.7
7.4
8
*
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
4.0
7.4
28
72
H31.4
ICD-10 Finland
Choroidal detachment
+∞
7.3
7
*
3626A
ICD-9 Finland
Other retinal disorders, Peripheral retinal degenerations
+∞
7.3
7
*
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
+∞
7.3
7
*
3742
FHL
Cryocoagulation under general anesthesia
+∞
7.3
7
*
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
+∞
7.3
7
*
A10AE06
ATC
insulin degludec; parenteral
3.9
7.2
28
74
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
20.2
7.1
10
5
CKD60
NOMESCO Finland
Anterior vitrectomy
8.9
7.1
14
16
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.0
574
4869
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.2
7.0
34
108
H04AA01
ATC
glucagon; nasal, parenteral
6.4
7.0
17
27
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.9
773
6971
H27.1
ICD-10 Finland
Dislocation of lens
13.9
6.9
11
8
CF2S4
NOMESCO Finland
Photography of conjunctiva
40.3
6.8
8
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
40.3
6.8
8
*
H18.1
ICD-10 Finland
Bullous keratopathy
22.7
6.7
9
*
R60.0
ICD-10 Finland
Localized oedema
1.9
6.6
99
554
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
4.8
6.6
20
42
H16.0
ICD-10 Finland
Corneal ulcer
2.6
6.5
44
173
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.6
6.5
46
184
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
6.4
82
433
S01FA04
ATC
cyclopentolate; ophthalmic
4.9
6.4
19
39
F05
ICPC
Visual disturbance other
3.4
6.4
28
83
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.7
6.3
25
68
37402
ICD-8 Finland
Cataract, Senilis
11.1
6.3
11
10
H21.0
ICD-10 Finland
Hyphaema
11.1
6.3
11
10
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
6.3
233
1678
H44.5
ICD-10 Finland
Degenerated conditions of globe
18.1
6.3
9
5
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
+∞
6.3
6
*
Q14.10
ICD-10 Finland
Congenital retinoschis
+∞
6.3
6
*
3690A
ICD-9 Finland
Blindness and low vision, Profound impairment, both eyes
+∞
6.3
6
*
3711
FHL
Cyclodiateria or cryocoagulation
+∞
6.3
6
*
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
+∞
6.3
6
*
74439
ICD-8 Finland
Congenital anomalies of eye, Cataracta NUD
+∞
6.3
6
*
8720/3-C69.3
ICD-O-3
Malignant melanoma, NOS, of choroid
+∞
6.3
6
*
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.4
6.3
21
49
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
6.3
428
3479
R51.80
ICD-10 Finland
Headache
1.8
6.2
108
636
C03CA01
ATC
furosemide; systemic
1.5
6.2
267
1985
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.3
6.1
29
91
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
7.7
6.1
13
17
F29
ICPC
Eye symptom/complaint other
2.1
6.1
69
349
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
6.0
168
1132

Mortality – FinRegistry

↥

Association

Association between endpoint H7_RETINALDETACHOTH and mortality.

Females

Parameter HR [95% CI] p-value
H7_RETINALDETACHOTH 1.211 [1.03, 1.42] 0.018
Birth year 0.992 [0.98, 1.0] 0.08

During the follow-up period (1.1.1998 — 31.12.2019), 411 out of 2315 females with H7_RETINALDETACHOTH died.

Males

Parameter HR [95% CI] p-value
H7_RETINALDETACHOTH 1.138 [0.98, 1.33] 0.096
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 492 out of 2585 males with H7_RETINALDETACHOTH died.

Mortality risk

Mortality risk for people of age

years, who have H7_RETINALDETACHOTH.

N-year risk Females Males
1 0.104% 0.207%
5 0.699% 1.414%
10 1.675% 3.391%
15 3.173% 6.485%
20 5.648% 10.842%

Relationships between endpoints

↥

Index endpoint: H7_RETINALDETACHOTH – Other, unspecified and serous retinal detachments

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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