Other, unspecified and serous retinal detachments

H7_RETINALDETACHOTH

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H33.2, H33.5
  • Hospital discharge: ICD-9 361[8-9]
  • Hospital discharge: ICD-8 376
  • Hospital discharge: excluded ICD-8 37602
  • Cause of death: ICD-10 H33.2, H33.5
  • Cause of death: ICD-9 361[8-9]
  • Cause of death: ICD-8 376
  • Cause of death: excluded ICD-8 37602

2 out of 7 registries used, show all original rules.

1199

4. Check minimum number of events

None

1199

5. Include endpoints

None

1199

6. Filter based on genotype QC (FinnGen only)

1179

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9905 4592 5209
Only index persons 7811 3666 4145
Unadjusted period prevalence (%)
Whole population 0.14 0.13 0.15
Only index persons 0.15 0.13 0.16
Median age at first event (years)
Whole population 59.61 61.44 58.09
Only index persons 58.28 60.41 56.39

-FinnGen-

Key figures

All Female Male
Number of individuals 1179 537 642
Unadjusted period prevalence (%) 0.25 0.19 0.29
Median age at first event (years) 59.23 58.96 59.45

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1199
Matched controls
11990
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
171.5
307.7
212
15
WX140
NOMESCO Finland
Parabulbar anesthesy
47.5
307.7
317
90
H33.5
ICD-10 Finland
Other retinal detachments
1711.1
307.7
680
9
H33.2
ICD-10 Finland
Serous retinal detachment
+∞
307.7
299
*
CKC12
NOMESCO Finland
Photocoagulation of retina
276.7
307.7
225
10
H33.0
ICD-10 Finland
Retinal detachment with retinal break
9194.9
307.7
539
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
11.0
244.9
298
349
CKD40
NOMESCO Finland
Endophotocoagulation of retina
+∞
230.9
214
*
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
2319.6
219.7
206
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
9.2
213.0
300
420
H43.1
ICD-10 Finland
Vitreous haemorrhage
39.3
205.2
127
36
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
2163.8
186.4
176
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
5.4
185.6
732
2683
Z96.1
ICD-10 Finland
Presence of intraocular lens
6.4
179.8
383
824
S01ED51
ATC
timolol, combinations; ophthalmic
8.2
177.9
272
415
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
255.7
174.4
175
8
H33.3
ICD-10 Finland
Retinal breaks without detachment
946.7
171.4
164
*
H26.4
ICD-10 Finland
After-cataract
6.6
148.4
278
521
37600
ICD-8 Finland
Detachment of retina, Primaria
+∞
144.8
136
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
7.1
142.1
245
421
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
46.9
134.0
79
18
H43.8
ICD-10 Finland
Other disorders of vitreous body
6.0
128.2
264
538
H26.2
ICD-10 Finland
Complicated cataract
29.4
126.5
85
31
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
47.8
122.7
72
16
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.0
121.4
617
2528
S01EC01
ATC
acetazolamide; systemic
13.8
101.8
97
76
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
99.4
94
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
98.3
93
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
8.0
97.6
140
194
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.1
97.4
342
1061
S01ED01
ATC
timolol; ophthalmic
8.6
92.5
125
161
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
477.3
90.5
89
*
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
89.7
85
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
88.7
84
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
44.3
85.4
51
12
XCH00
NOMESCO Finland
Eye pressure measurement
7.3
83.3
129
194
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
809.0
78.3
76
*
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
111.4
77.0
83
8
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
14.4
72.9
67
49
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
71.6
68
*
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
185.6
67.8
70
*
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
+∞
66.3
63
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
64.1
61
*
37601
ICD-8 Finland
Detachment of retina, Secundaria
+∞
62.0
59
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
221.4
61.7
63
*
S01EA03
ATC
apraclonidine; ophthalmic
20.3
61.0
47
24
XCK10
NOMESCO Finland
Photography of fundus of eye
4.2
59.7
175
465
S01EA05
ATC
brimonidine; ophthalmic
8.0
58.3
81
107
H25.1
ICD-10 Finland
Senile nuclear cataract
2.7
57.2
449
2162
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
103.4
54.3
59
6
H26.02
ICD-10 Finland
Presenil cataract
7.4
52.6
78
111
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
13.9
50.4
47
35
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
47.2
45
*
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
43.0
41
*
S01EE01
ATC
latanoprost; ophthalmic
4.0
42.4
131
359
114
Kela drug reimbursment
Glaucoma
3.4
42.2
171
562
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.0
40.3
209
794
ZXA00
NOMESCO Finland
Right side
2.3
38.8
405
2154
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
38.6
570
3494
S01BC03
ATC
diclofenac; ophthalmic
7.2
38.0
57
82
XCK00
NOMESCO Finland
Perimetry
4.1
36.4
107
282
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
10.6
36.2
40
39
WX002
NOMESCO Finland
Sedation and analgesia
2.4
35.5
297
1426
H3603, E103,
ICD-10 Finland
+∞
34.5
33
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.7
34.3
82
184
3745
FHL
Hard membrane girding, cerclage with coagulation
346.6
34.1
34
*
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
33.5
32
*
S01BC05
ATC
ketorolac; ophthalmic
4.5
33.3
85
201
3643
FHL
Vitrectomy through pars Plana
336.0
33.0
33
*
H52.1
ICD-10 Finland
Myopia
5.6
32.9
64
120
H35.4
ICD-10 Finland
Peripheral retinal degeneration
120.1
32.8
35
*
A10AA01, ,
ATC
8.0
32.1
44
57
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
+∞
31.4
30
*
S01EC04
ATC
brinzolamide; ophthalmic
4.3
30.8
83
205
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
47.6
30.7
37
8
H53.1
ICD-10 Finland
Subjective visual disturbances
3.5
30.7
112
342
3618X
ICD-9 Finland
Retinal detachments and defects, Other forms of retinal detachment
+∞
30.3
29
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
6.1
30.1
53
90
A10AB01
ATC
insulin (human); parenteral
6.0
29.8
53
91
A10AA02, ,
ATC
6.0
29.8
53
91
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
29.3
28
*
ZXA05
NOMESCO Finland
Left side
2.1
29.2
356
1980
S01EC54
ATC
brinzolamide, combinations; ophthalmic
8.5
28.4
37
45
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
28.2
27
*
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
28.2
27
*
3619X
ICD-9 Finland
Retinal detachments and defects, Unspecified retinal detachment
+∞
28.2
27
*
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
40.0
28.1
35
9
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
277.0
26.8
27
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
277.0
26.8
27
*
H34.8
ICD-10 Finland
Other retinal vascular occlusions
99.0
26.8
29
*
37609
ICD-8 Finland
Detachment of retina, Unspecified
+∞
26.1
25
*
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
7.0
25.6
39
57
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
5.0
24.8
54
112
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
92.1
24.7
27
*
3747
FHL
Combined ablation and vitreous surgery with coagulation
+∞
24.0
23
*
XCD20
NOMESCO Finland
Photoangiography of eye
33.0
22.5
29
9
S01EC03
ATC
dorzolamide; ophthalmic
6.6
22.3
36
56
37603
ICD-8 Finland
Detachment of retina, Retinoschisis
+∞
21.9
21
*
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
+∞
21.9
21
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
117.2
21.6
23
*
H57.1
ICD-10 Finland
Ocular pain
4.1
21.3
60
153
ZXA10
NOMESCO Finland
Bilateral
2.1
21.2
239
1271
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.0
21.0
61
159
XCW10
NOMESCO Finland
Assessment of vision
8.2
20.9
28
35
H3603, E113,
ICD-10 Finland
+∞
20.9
20
*
H35.37
ICD-10 Finland
Macular holes
213.6
20.6
21
*
T89
ICPC
Diabetes insulin dependent
4.5
20.5
51
118
S01FA01
ATC
atropine; ophthalmic
29.5
19.7
26
9
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
6.8
19.2
30
45
H3600, E113,
ICD-10 Finland
+∞
18.8
18
*
H27.0
ICD-10 Finland
Aphakia
24.1
18.7
26
11
H40.0
ICD-10 Finland
Glaucoma suspect
2.6
18.5
111
448
A10AC01
ATC
insulin (human); parenteral
2.8
18.4
98
372
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
7.2
18.3
27
38
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.8
18.1
55
148
H54.4
ICD-10 Finland
Blindness, monocular
33.5
18.0
23
7
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.3
17.8
36
70
H3601, E103,
ICD-10 Finland
+∞
17.7
17
*
H3601, E113,
ICD-10 Finland
+∞
17.7
17
*
H25.8
ICD-10 Finland
Other senile cataract
2.3
17.1
146
692
CKC15
NOMESCO Finland
Panretinal photocoagulation
64.3
16.8
19
*
A10AB05
ATC
insulin aspart; parenteral
2.7
16.7
96
380
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
91.4
16.6
18
*
H35.36
ICD-10 Finland
Macular cyst
172.3
16.5
17
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
20.4
16.5
24
12
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
16.2
437
3027
H20.1
ICD-10 Finland
Chronic iridocyclitis
13.0
16.2
28
22
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
16.1
118
524
S01EE03
ATC
bimatoprost; ophthalmic
4.1
16.0
44
110
H43.3
ICD-10 Finland
Other vitreous opacities
5.8
15.9
29
51
37002
ICD-8 Finland
Refractive errors, Myopia
33.9
15.8
20
6
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
+∞
15.7
15
*
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
162.0
15.5
16
*
H35.8
ICD-10 Finland
Other specified retinal disorders
162.0
15.5
16
*
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
162.0
15.5
16
*
CKA10
NOMESCO Finland
Biopsy of vitreous body
162.0
15.5
16
*
H53.4
ICD-10 Finland
Visual field defects
4.4
15.3
38
88
3661A
ICD-9 Finland
Cataract, Senile cataract
6.2
15.2
26
43
ZXD05
NOMESCO Finland
Urgent procedure
1.7
14.8
364
2448
A10AE05
ATC
insulin detemir; parenteral
2.9
14.7
69
245
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
36.5
14.5
18
5
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
17.2
14.3
22
13
S01EE05
ATC
tafluprost; ophthalmic
3.1
13.9
58
192
H33
ICD-10 Finland
Retinal detachments and breaks
54.0
13.8
16
*
37700
ICD-8 Finland
Other diseases of retina and optic nerve, Haemorrhagia corporis vitrei
+∞
13.6
13
*
CKC75
NOMESCO Finland
Removal of cerclage from sclera
+∞
13.6
13
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
13.4
319
2117
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
26.1
13.4
18
7
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
13.2
12.9
22
17
H36.00
ICD-10 Finland
Diabetic background retinopathy
50.6
12.9
15
*
H54.0
ICD-10 Finland
Blindness, binocular
50.6
12.9
15
*
H54.1
ICD-10 Finland
Severe visual impairment, binocular
50.6
12.9
15
*
H36.01
ICD-10 Finland
Diabetic maculopathy
50.6
12.9
15
*
CKD30
NOMESCO Finland
Internal drainage of subretinal fluid
+∞
12.5
12
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.8
12.4
38
103
S01BA01
ATC
dexamethasone; ophthalmic
3.0
12.3
55
190
S01EX03, ,
ATC
3.9
12.2
36
95
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
12.1
105
500
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
18.3
12.1
18
10
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
27.0
12.1
16
6
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.7
12.0
67
261
F05
ICPC
Visual disturbance other
3.3
11.9
44
136
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
16.6
11.7
18
11
H44.0
ICD-10 Finland
Purulent endophthalmitis
65.6
11.6
13
*
H44.2
ICD-10 Finland
Degenerative myopia
65.6
11.6
13
*
H04AA01
ATC
glucagon; nasal, parenteral
5.8
11.5
21
37
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
11.5
11
*
3649
FHL
Other measure in this category
+∞
11.5
11
*
H3600, E103,
ICD-10 Finland
+∞
11.5
11
*
CKD25
NOMESCO Finland
External drainage of subretinal fluid
+∞
11.5
11
*
37403
ICD-8 Finland
Cataract, Complicata
+∞
11.5
11
*
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
121.1
11.4
12
*
A10AD01
ATC
insulin (human); parenteral
5.1
11.0
23
46
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
14.0
11.0
18
13
F29
ICPC
Eye symptom/complaint other
2.1
10.9
111
563
A10AB04
ATC
insulin lispro; parenteral
3.7
10.8
34
94
A10AE04
ATC
insulin glargine; parenteral
2.1
10.7
111
567
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
10.6
126
676
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
111.0
10.4
11
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
10.4
10
*
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
32.8
10.3
13
*
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
32.8
10.3
13
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
19.0
10.3
15
8
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.4
10.0
68
292
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
40.4
10.0
12
*
H44.5
ICD-10 Finland
Degenerated conditions of globe
26.3
9.8
13
5
87011
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Complicata
26.3
9.8
13
5
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
9.7
72
321
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
9.7
150
876
S01BA04
ATC
prednisolone; ophthalmic
3.5
9.6
33
97
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.5
9.5
32
93
37520
ICD-8 Finland
Glaucoma, Secondary
100.8
9.4
10
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
100.8
9.4
10
*
H34.2
ICD-10 Finland
Other retinal artery occlusions
100.8
9.4
10
*
3759
FHL
Other measure in this category
+∞
9.4
9
*
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
5.2
9.4
19
37
S01AX11
ATC
[U] ofloxacin
2.8
9.4
46
168
Z3231
NOMESCO Finland
Registered nurse
1.5
8.8
302
2161
H27.1
ICD-10 Finland
Dislocation of lens
11.7
8.6
15
13
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
27.7
8.5
11
*
37405
ICD-8 Finland
Cataract, Traumatica
20.2
8.5
12
6
H35.9
ICD-10 Finland
Retinal disorder, unspecified
20.2
8.5
12
6
A10AE06
ATC
insulin degludec; parenteral
2.9
8.4
38
133
H21.0
ICD-10 Finland
Hyphaema
12.9
8.4
14
11
S01EB01
ATC
pilocarpine; ophthalmic
7.9
8.4
18
23
3852
FHL
Reoperation for another reason
+∞
8.3
8
*
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
+∞
8.3
8
*
3742
FHL
Cryocoagulation under general anesthesia
+∞
8.3
8
*
S01EE04
ATC
travoprost; ophthalmic
3.4
8.1
29
88
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
33.6
8.1
10
*
WZC30
NOMESCO Finland
Teaching
1.6
8.1
179
1154
H54.7
ICD-10 Finland
Unspecified visual loss
8.5
7.8
16
19
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.8
416
3237
ZXE00
NOMESCO Finland
One hour or less
1.4
7.7
419
3268
H44.1
ICD-10 Finland
Other endophthalmitis
45.3
7.7
9
*
E10
ICD-10 Finland
Type 1 diabetes mellitus
6.0
7.7
20
34
SFA10
NOMESCO Finland
One-surface restoration
1.4
7.7
558
4581
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.7
248
1746
S01BA07
ATC
fluorometholone; ophthalmic
3.8
7.6
23
62
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
18.5
7.6
11
6
177
Kela drug reimbursment
Insulin glargine 300 U / ml
3.6
7.6
24
67
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
7.5
85
448
H16.0
ICD-10 Finland
Corneal ulcer
2.3
7.5
58
264
A02BC02
ATC
pantoprazole; systemic
1.4
7.5
755
6545
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
80.6
7.4
8
*
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.6
7.3
23
64
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
7.3
7
*
H31.4
ICD-10 Finland
Choroidal detachment
+∞
7.3
7
*
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
+∞
7.3
7
*
3626A
ICD-9 Finland
Other retinal disorders, Peripheral retinal degenerations
+∞
7.3
7
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
7.3
217
1500
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.4
7.2
50
217
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.5
7.2
43
174
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
7.2
565
4682
CFB00
NOMESCO Finland
Suture of conjunctiva
30.2
7.2
9
*
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
20.1
7.1
10
5
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
20.1
7.1
10
5
TCG10
NOMESCO Finland
Removal of sutures from cornea
8.0
7.1
15
19
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
8.0
7.1
15
19
37402
ICD-8 Finland
Cataract, Senilis
12.1
7.1
12
10
H26.1
ICD-10 Finland
Traumatic cataract
12.1
7.1
12
10
N02BE01
ATC
paracetamol; systemic, rectal
1.5
7.0
1010
9295
D01
ICPC
Abdominal pain/cramps general
1.8
7.0
112
661
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.7
6.9
36
137
CHC05
NOMESCO Finland
Iridotomy
3.7
6.8
21
58
37404
ICD-8 Finland
Cataract, Secundaria
40.3
6.8
8
*
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
40.3
6.8
8
*
87091
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Sequelae
40.3
6.8
8
*
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.6
6.7
37
145
R60.0
ICD-10 Finland
Localized oedema
1.7
6.6
131
821
H50.1
ICD-10 Finland
Divergent concomitant strabismus
8.7
6.6
13
15
ZX198
NOMESCO Finland
Other local administration
6.9
6.5
15
22
S01FA04
ATC
cyclopentolate; ophthalmic
3.7
6.5
20
55
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
70.2
6.4
7
*
Q14.10
ICD-10 Finland
Congenital retinoschis
70.2
6.4
7
*
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
70.2
6.4
7
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
70.2
6.4
7
*
S01AA01
ATC
chloramphenicol; ophthalmic
2.2
6.4
53
249
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
6.0
6.3
16
27
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
18.1
6.3
9
5
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
+∞
6.3
6
*
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
6.3
6
*
3711
FHL
Cyclodiateria or cryocoagulation
+∞
6.3
6
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
6.3
6
*
37711
ICD-8 Finland
Other diseases of retina and optic nerve, Degeneratio retinae
+∞
6.3
6
*
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
6.3
6
*
3639
FHL
Other measure in this category
26.8
6.2
8
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
6.2
733
6421
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
6.2
657
5661
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.3
6.2
46
207

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
695
5809
1.47
9.40
5.4
5.0
7.04
6.69
mmol/l
3.01
663
5471
622
5126
1.44
8.82
7.2
6.4
12.61
11.81
umol/l
0.58
583
4882
596
4889
1.44
8.58
8.6
6.9
1.22
1.21
mmol/l
1.17
509
4156
1030
9487
1.61
7.50
19.2
15.2
22.22
25.59
mg/l
2.73
863
7605
398
3091
1.43
7.46
4.2
3.7
17.04
8.70
mg/mmol
1.56
269
1982
845
7499
1.43
7.18
9.1
7.6
80.81
79.10
u/l
0.38
794
7051
373
2895
1.42
6.91
4.9
4.1
7.39
7.40
ph
0.89
66
574
515
4228
1.38
6.84
5.5
4.9
34.70
35.18
g/l
1.07
478
3954
651
5554
1.38
6.80
10.2
9.0
4.35
4.14
e9/l
1.15
577
4858
571
4787
1.37
6.57
19.5
16.1
1.30
1.29
inr
0.03
173
1401
165
1103
1.58
6.37
2.1
1.7
—
—
—
0
0
508
4204
1.36
6.25
10.7
9.7
0.00
0.00
e9/l
0.15
432
3441
381
3043
1.37
5.76
3.6
3.1
7.33
7.70
mmol/l
0.91
331
2553
560
4745
1.34
5.74
6.6
5.7
0.04
0.04
e9/l
0.43
497
4098
558
4736
1.33
5.61
6.5
5.6
0.61
0.60
e9/l
0.31
497
4089
1060
9961
1.55
5.60
22.4
17.8
4.00
3.99
mmol/l
0.96
1044
9696
373
2983
1.36
5.56
3.7
3.3
38.22
84.12
e6/l
1.13
303
2338
1057
9933
1.54
5.51
22.3
17.7
139.56
139.67
mmol/l
0.65
1043
9686
569
4851
1.33
5.51
6.7
5.7
1.98
1.93
e9/l
0.11
516
4269
261
1974
1.41
5.43
3.5
2.9
514.70
552.40
mosm/kgh2o
2.34
224
1709
364
2915
1.36
5.34
3.7
3.1
385.91
243.13
mg/l
0.27
252
1891
384
3107
1.35
5.25
3.5
3.3
31.85
39.37
u/l
0.80
360
2949
529
4486
1.32
5.23
7.5
6.3
1.21
1.21
mmol/l
0.42
493
4099
525
4456
1.32
5.12
7.4
6.2
—
—
—
0
0
198
1442
1.45
5.05
3.3
2.5
2.19
2.29
g/l
1.86
189
1331
570
4901
1.31
5.04
6.8
5.9
0.19
0.19
e9/l
0.04
512
4292
550
4708
1.31
5.01
4.0
3.6
0.00
0.00
estimate
0.50
92
856
770
6911
1.32
4.91
4.2
4.0
—
—
—
0
0
544
4659
1.31
4.90
5.4
4.9
0.00
0.00
estimate
0.50
98
881
1027
9641
1.45
4.90
5.4
5.0
2.68
2.72
mmol/l
0.70
954
8850
136
924
1.53
4.89
10.8
7.5
10.87
10.12
mmol/l
0.54
131
877
22
78
2.85
4.83
1.1
1.2
—
—
—
0
0
783
7056
1.32
4.79
4.9
4.0
14.82
12.82
mm/h
2.36
726
6510
340
2735
1.34
4.76
3.7
3.2
0.59
0.46
e6/l
0.39
276
2107
533
4565
1.30
4.76
6.9
5.9
26.71
27.39
%
0.71
509
4289
1008
9446
1.42
4.71
4.9
4.5
4.57
4.61
mmol/l
0.54
940
8731
458
3852
1.31
4.65
4.3
3.8
72.66
53.08
ng/l
0.32
335
2789
369
3015
1.32
4.61
2.6
2.1
237.58
234.93
u/l
0.02
344
2835
543
4675
1.30
4.61
3.9
3.6
0.01
0.00
estimate
0.42
105
942
1002
9390
1.41
4.59
4.9
4.4
1.42
1.44
mmol/l
0.59
930
8626
524
4496
1.29
4.55
6.7
5.7
58.16
57.42
%
0.70
500
4221
1070
10154
1.50
4.53
12.8
10.5
26.31
26.73
u/l
0.30
1032
9784
115
767
1.55
4.50
4.1
4.1
0.13
0.13
%
0.00
31
260
127
868
1.52
4.45
3.1
2.7
73.47
69.78
e9/l
0.54
97
674
129
886
1.51
4.42
3.5
3.0
186.71
217.25
ng/l
0.44
119
826
183
1347
1.42
4.39
7.7
5.7
1.07
1.03
mmol/l
1.50
170
1236
203
1524
1.40
4.36
1.3
1.3
30.78
35.01
iu/ml
0.19
69
495
125
856
1.51
4.34
2.6
2.9
67.00
66.52
g/l
0.30
114
785
22
83
2.68
4.34
2.2
2.3
—
—
—
0
0
371
3057
1.31
4.32
2.8
2.5
53.51
86.15
u/l
0.67
342
2834
518
4460
1.28
4.31
6.9
5.8
2.86
2.87
%
0.03
491
4173
120
819
1.52
4.24
4.1
4.0
1.17
0.96
%
0.32
36
311
109
729
1.54
4.22
4.0
4.2
0.15
0.50
%
0.40
26
224
519
4479
1.28
4.21
7.2
6.1
8.76
8.77
%
0.03
490
4196
526
4550
1.28
4.17
3.1
2.6
—
—
—
0
0
1040
9846
1.42
4.16
17.9
14.4
—
—
—
0
0
1100
10530
1.54
4.13
27.6
22.1
6.84
6.74
e9/l
0.38
1076
10216
502
4322
1.28
4.12
6.9
5.8
0.67
0.66
%
0.17
476
4037
1100
10531
1.54
4.11
27.5
22.0
91.38
91.32
fl
0.16
1088
10364
1100
10532
1.54
4.10
27.5
22.0
30.43
30.42
pg
0.06
1088
10364
1100
10533
1.54
4.09
27.6
22.1
4.47
4.48
e12/l
0.27
1076
10219
247
1934
1.35
4.07
4.1
4.0
249.80
457.08
ng/l
1.34
198
1564
1099
10523
1.53
4.07
27.6
22.2
39.96
40.12
%
0.32
1031
9804
1100
10535
1.53
4.06
27.8
22.2
135.14
135.44
g/l
0.26
1090
10363
969
9078
1.35
4.05
4.4
4.0
1.32
1.31
mmol/l
0.15
890
8274
206
1569
1.38
4.05
2.2
2.1
29.86
29.84
s
0.02
197
1517
926
8622
1.32
4.01
5.0
4.6
1.90
2.11
mu/l
0.78
854
7840
80
504
1.63
4.00
3.6
3.5
—
—
—
0
0
1099
10529
1.52
3.99
27.7
22.1
244.33
245.16
e9/l
0.16
1077
10241
203
1551
1.37
3.91
3.4
2.5
12.96
12.95
umol/l
0.01
194
1443
406
3426
1.28
3.86
4.6
3.8
60.71
118.83
e6/l
1.29
317
2499
134
954
1.46
3.85
5.1
3.6
1.97
2.07
mmol/l
0.13
120
788
180
1355
1.39
3.79
3.6
2.6
24.26
23.03
%
0.46
160
1156
341
2821
1.29
3.78
4.8
4.4
—
—
—
0
0
295
2394
1.31
3.77
8.1
6.9
—
—
—
0
0
262
2095
1.32
3.72
2.9
2.6
3.81
5.20
e6/l
1.45
237
1907
304
2482
1.30
3.71
4.2
4.0
85.37
88.40
%
1.12
290
2425
61
366
1.70
3.68
2.0
2.8
10.92
10.71
g/l
0.11
55
326
955
8971
1.32
3.60
6.8
5.7
41.61
39.85
mmol/mol
5.30
904
8288
156
1157
1.40
3.59
2.9
2.5
1.88
1.81
%
0.37
142
1036
103
706
1.50
3.59
2.3
2.7
—
—
—
0
0
161
1202
1.39
3.57
6.5
8.1
0.59
1.14
mmol/l
1.32
135
955
350
2927
1.28
3.52
3.3
3.1
—
—
—
0
0
771
7061
1.26
3.51
4.1
3.8
15.02
14.88
pmol/l
0.78
699
6404
107
743
1.48
3.51
3.6
3.8
0.97
0.67
%
0.36
31
267
156
1162
1.39
3.50
1.5
1.3
461.62
504.35
titre
0.11
37
248
54
318
1.73
3.50
1.3
1.2
0.50
1.31
u/ml
—
10
23
216
1696
1.33
3.47
3.1
2.8
1.21
1.01
e6/l
0.42
145
987
160
1199
1.39
3.47
6.5
8.1
5.02
5.12
kpa
0.89
154
1147
160
1200
1.38
3.45
6.5
8.1
12.71
11.95
kpa
0.77
155
1150
147
1090
1.40
3.39
6.9
8.4
95.36
95.51
%
0.10
141
1051
45
254
1.80
3.37
4.4
4.5
—
—
—
0
0
318
2644
1.28
3.33
3.7
3.2
—
—
—
0
0
46
263
1.78
3.31
3.6
3.3
1.62
1.65
mg/l
0.11
41
244
14
48
2.94
3.30
2.1
3.0
1167.21
1042.88
u/ml
0.12
14
48
302
2498
1.28
3.30
3.3
3.4
—
—
—
0
0
186
1441
1.34
3.27
2.2
2.1
—
—
—
0
0
202
1587
1.33
3.23
3.3
3.0
2.77
2.10
e6/l
0.49
130
888
24
110
2.21
3.20
1.8
1.3
—
—
—
0
0
26
125
2.10
3.10
1.3
1.2
2.58
7.34
u/ml
1.05
12
53
722
6612
1.23
3.08
5.2
4.2
—
—
—
0
0
438
3809
1.24
3.07
2.5
2.2
77.73
77.53
nmol/l
0.05
397
3406
443
3861
1.23
3.03
3.4
2.8
145.11
151.37
ug/l
0.19
409
3538
987
9380
1.30
2.94
5.0
4.7
6.15
5.99
mmol/l
2.73
904
8517
8
17
4.73
2.92
1.1
1.0
—
—
—
0
0
117
859
1.40
2.88
7.9
8.8
—
—
—
0
0
870
8157
1.24
2.84
23.1
18.0
14.55
15.10
%
2.63
861
8007
233
1900
1.28
2.82
1.8
1.7
1180.32
1183.33
nmol/l
0.02
189
1432
350
2997
1.24
2.78
3.9
3.1
2134.67
1476.23
ng/l
1.32
314
2558
689
6320
1.21
2.74
5.1
4.4
2.83
2324.96
e6/l
—
6
102
53
335
1.61
2.70
2.3
2.1
21.65
21.42
s
0.16
46
298
73
497
1.50
2.68
1.9
1.8
1.41
1.60
g/l
1.06
68
429
11
35
3.16
2.64
1.2
1.3
—
—
—
0
0
40
239
1.70
2.53
2.1
2.2
278.13
114.90
ug/min
0.56
23
143
842
7908
1.22
2.50
24.7
19.5
331.91
332.56
g/l
1.32
837
7847
50
319
1.59
2.47
2.1
2.7
37.24
37.49
g/l
0.10
44
280
33
188
1.78
2.47
1.4
1.6
—
—
—
0
0
455
4047
1.20
2.41
2.2
2.0
96.92
93.69
pmol/l
0.69
252
2117
32
182
1.78
2.41
3.8
1.4
0.87
0.85
nmol/l
0.06
27
154
98
722
1.39
2.40
4.9
5.2
—
—
—
0
0
21
104
2.04
2.37
1.9
1.3
—
—
nmol/l
—
0
0
149
1174
1.31
2.35
1.6
1.4
—
—
—
0
0
101
753
1.37
2.31
6.6
3.8
112.12
89.74
ng/l
1.20
85
650
25
134
1.88
2.28
3.5
2.6
—
—
—
0
0
69
484
1.45
2.23
2.3
2.3
—
—
—
0
0
14
60
2.35
2.22
2.8
2.6
696.22
628.54
e6/l
—
9
54
10
35
2.87
2.21
3.6
2.4
—
—
—
0
0
69
486
1.45
2.19
4.0
3.4
4.47
4.48
pmol/l
0.03
62
423
21
108
1.96
2.16
1.1
1.3
59.30
65.73
u/ml
—
5
6
43
276
1.58
2.11
1.1
1.1
—
—
—
0
0
14
62
2.27
2.08
1.4
1.1
—
—
—
0
0
79
577
1.40
2.07
8.3
11.0
—
—
—
0
0
19
97
1.97
2.01
1.1
2.5
—
—
—
0
0
291
2523
1.20
1.99
1.8
1.7
1.40
1.39
mmol/l
0.03
247
2114
248
2120
1.21
1.96
1.7
1.7
454.40
28027715.50
pmol/l
1.92
203
1759
374
3320
1.18
1.96
4.1
3.4
2.36
2.35
mmol/l
0.40
327
2921
275
2376
1.20
1.95
1.7
1.6
18.89
20.28
nmol/l
0.97
245
2029
351
3101
1.19
1.94
3.2
2.4
—
—
—
0
0
8
27
2.98
1.93
1.1
1.1
—
—
—
0
0
8
27
2.98
1.93
1.0
1.0
—
—
—
0
0
11
45
2.46
1.93
1.3
1.2
—
66.12
%
—
0
8
89
672
1.35
1.92
4.9
3.7
5.07
5.17
kpa
0.62
84
645
39
251
1.57
1.91
1.7
1.7
9986.38
15177.62
e6/l
0.60
26
182
114
893
1.31
1.91
2.3
2.4
28.73
40.07
u/l
1.37
99
769
302
2642
1.19
1.86
3.0
2.7
2414.19
7039.52
umol/l
1.96
269
2310
195
1636
1.23
1.85
3.8
3.4
0.82
0.82
mmol/l
0.32
187
1535
31
190
1.65
1.85
1.5
1.4
—
—
—
0
0
418
3762
1.17
1.83
3.8
3.4
5.81
5.85
ph
0.10
21
265
117
926
1.29
1.83
1.9
1.6
—
—
—
0
0
14
66
2.13
1.82
1.1
1.1
—
—
—
0
0
41
271
1.53
1.81
1.1
1.1
—
—
—
0
0
8
29
2.77
1.79
8.4
4.5
—
—
—
0
0
240
2068
1.20
1.75
4.2
4.0
1.01
1.02
kg/l
1.57
31
290
8
30
2.68
1.72
1.5
1.5
—
—
—
0
0
86
660
1.33
1.69
5.0
3.7
7.43
7.41
ph
—
6
87
8
31
2.59
1.66
1.3
1.5
—
—
—
0
0
8
31
2.59
1.66
1.1
1.1
1888.88
1575.55
miu/ml
—
8
31
134
1096
1.25
1.62
2.8
2.7
9.97
9.03
umol/l
0.22
114
949
22
128
1.73
1.61
1.2
1.1
2.54
2.58
u/ml
—
10
70
17
91
1.88
1.61
1.0
1.0
9.74
2.64
u/ml
—
8
43
65
482
1.37
1.61
5.0
3.9
—
—
—
0
0
21
121
1.75
1.59
1.7
1.6
48.55
65.81
%
0.82
11
78
49
347
1.43
1.58
5.1
7.0
1.26
1.33
mmol/l
0.28
43
305
279
2460
1.17
1.56
2.5
2.1
3.16
3.05
mg/l
0.28
248
2081
15
78
1.93
1.54
1.1
1.2
—
—
—
0
0
7
27
2.60
1.51
1.1
1.6
—
—
—
0
0
92
729
1.28
1.46
2.9
2.9
11.10
10.67
g/l
0.47
85
667
237
2074
1.18
1.45
2.8
1.7
1.42
1.23
mg/l
0.21
184
1603
37
253
1.48
1.44
2.4
2.5
—
—
—
0
0
412
3765
1.14
1.41
2.2
2.2
—
—
—
0
0
15
81
1.86
1.40
1.3
1.1
110.00
151.25
titre
—
5
16
15
81
1.86
1.40
1.9
2.1
877.11
640.91
ml
—
9
53
9
40
2.26
1.40
2.6
2.8
—
—
—
0
0
33
223
1.49
1.37
1.2
1.2
1.20
2.75
u/ml
—
5
22
126
1046
1.23
1.36
1.8
1.5
—
—
—
0
0
11
54
2.05
1.33
1.5
1.4
—
—
—
0
0
5
18
2.78
1.28
1.0
1.7
—
—
—
0
0
213
1868
1.17
1.28
2.8
3.1
2.46
2.46
mmol/l
0.19
186
1647
33
227
1.47
1.27
3.5
3.0
—
—
—
0
0
15
84
1.80
1.27
1.0
1.0
18.44
2.77
u/ml
—
7
29
43
312
1.39
1.25
10.2
10.7
—
—
—
0
0
16
92
1.75
1.25
1.4
1.4
42.25
27.65
%
—
8
61
32
220
1.47
1.24
4.3
4.4
—
—
—
0
0
51
672
0.75
1.23
1.2
1.2
—
—
—
0
0
111
920
1.23
1.23
2.3
2.5
6.11
7.59
ug/l
0.63
97
806
146
1245
1.20
1.22
2.0
1.7
—
—
—
0
0
78
624
1.27
1.19
2.6
2.9
—
—
—
0
0
8
38
2.11
1.18
1.1
1.1
175.38
258.75
iu/ml
—
8
38
65
509
1.29
1.17
1.6
1.6
—
—
—
0
0
5
113
0.44
1.13
2.8
1.5
—
—
—
0
0
13
73
1.79
1.11
1.6
1.5
0.86
1.02
g/l
0.91
13
73
25
168
1.50
1.10
2.6
3.3
—
—
—
0
0
8
41
1.96
1.09
1.1
1.3
—
—
—
0
0
276
2498
1.14
1.08
1.4
1.4
—
—
—
0
0
11
59
1.87
1.07
1.2
1.3
1.56
1.57
g/l
0.03
11
59
18
113
1.60
1.06
1.1
1.0
35.23
5.98
u/ml
—
8
56
322
2949
1.13
1.04
4.6
3.9
—
—
—
0
0
55
429
1.30
1.04
1.7
1.9
—
—
—
0
0
62
492
1.27
1.03
1.2
1.2
—
—
—
0
0
25
171
1.47
1.03
1.6
1.5
—
—
—
0
0
73
593
1.25
1.01
1.5
1.5
—
—
—
0
0
99
831
1.21
1.01
3.3
4.1
1.23
1.23
mmol/l
0.01
87
731
13
76
1.72
0.99
1.1
1.1
—
—
—
0
0
35
258
1.37
0.97
1.3
1.2
—
1367.14
—
0
7
7
36
1.95
0.97
1.0
1.1
—
—
—
0
0
34
250
1.37
0.96
1.2
1.4
22.27
30.84
iu/l
0.85
29
212
14
85
1.65
0.94
3.4
2.5
11.29
10.82
%
0.15
14
85
33
243
1.37
0.93
1.3
1.2
70.00
85.88
titre
—
6
17
22
150
1.48
0.93
3.1
2.2
—
—
—
0
0
21
142
1.49
0.92
1.3
1.2
—
—
—
0
0
353
3272
1.11
0.92
3.1
2.9
—
—
—
0
0
167
1480
1.15
0.91
1.3
1.2
7.40
11.41
u/ml
0.61
70
550
102
870
1.19
0.89
1.4
1.4
—
—
—
0
0
18
119
1.52
0.88
1.4
1.2
—
—
—
0
0
643
6151
1.10
0.88
3.4
3.2
57.14
53.69
u/l
0.29
595
5732
243
2213
1.12
0.87
4.3
3.5
—
—
—
0
0
22
153
1.45
0.86
1.8
1.4
93.10
135.38
u/ml
—
6
26
71
588
1.22
0.85
2.3
1.8
2.11
1.50
g/l
0.41
65
537
124
1082
1.16
0.84
4.1
4.2
15.27
17.66
ug/l
0.13
104
895
17
113
1.51
0.82
1.1
1.0
11.90
1.71
u/ml
—
7
43
54
436
1.25
0.82
2.4
2.0
0.50
1.67
ug/l
2.46
49
386
16
105
1.53
0.82
1.1
1.0
5.64
1.26
u/ml
—
8
51
8
47
1.71
0.80
1.5
1.3
—
1.10
%
—
0
10
38
294
1.30
0.80
3.2
3.2
—
—
—
0
0
275
2535
1.11
0.80
4.4
4.0
0.00
0.00
estimate
0.69
91
839
78
658
1.20
0.79
8.7
9.8
0.61
0.68
%
0.96
78
653
8
48
1.67
0.79
1.5
1.4
12.66
6.61
ug/l
—
8
40
11
175
0.63
0.78
1.1
1.3
—
—
—
0
0
23
165
1.40
0.78
1.7
1.4
—
—
—
0
0
78
660
1.19
0.77
8.7
9.7
1.31
1.31
%
0.01
78
655
21
149
1.42
0.76
1.0
1.0
—
—
—
0
0
259
2388
1.11
0.75
3.3
2.4
—
—
—
0
0
5
24
2.09
0.74
1.8
1.5
—
—
—
0
0
109
953
1.16
0.74
2.5
2.2
0.20
0.21
g/l
0.60
103
887
9
56
1.61
0.72
1.7
2.8
—
—
—
0
0
15
218
0.68
0.72
3.7
3.5
31.89
26.45
mg/l
—
9
145
35
273
1.29
0.72
1.1
1.1
—
—
—
0
0
31
238
1.31
0.71
1.2
1.2
—
—
—
0
0
29
221
1.32
0.70
1.6
1.4
670.13
978.87
e6/l
0.15
24
182
42
337
1.26
0.70
2.7
3.6
45.68
72.34
mg/l
0.69
36
270
9
58
1.56
0.70
1.1
1.0
—
—
—
0
0
13
86
1.52
0.66
1.3
1.2
—
—
—
0
0
28
215
1.31
0.65
2.9
2.7
15.29
15.89
%
0.26
14
110
11
70
1.58
0.65
1.5
1.5
89.45
83.11
umol/l
0.32
11
70
13
87
1.50
0.63
3.5
3.1
13.21
13.21
%
0.01
13
87
21
155
1.36
0.63
1.3
1.2
301.38
285.28
u/ml
0.11
16
94
422
4011
1.08
0.63
5.2
4.8
2.70
2.80
ug/l
0.09
379
3600
36
288
1.26
0.63
1.3
1.5
301.70
284.03
ug/g
0.21
20
171
17
121
1.41
0.62
4.5
4.4
—
—
—
0
0
50
416
1.21
0.62
1.3
1.2
—
—
—
0
0
39
478
0.81
0.62
1.6
1.5
—
—
—
0
0
10
63
1.59
0.62
2.2
1.6
—
—
—
0
0
8
52
1.54
0.59
4.0
1.2
5.66
7.54
u/l
—
8
39
17
231
0.73
0.58
1.8
1.6
—
—
—
0
0
41
337
1.22
0.58
2.8
3.6
42.04
58.19
mg/l
0.34
34
269
30
238
1.27
0.57
2.0
1.6
—
—
—
0
0
11
73
1.51
0.56
1.8
2.0
1.76
2.68
ug/l
0.88
11
65
15
107
1.41
0.55
1.1
1.7
—
—
—
0
0
15
107
1.41
0.55
1.3
1.3
—
—
—
0
0
55
643
0.85
0.55
1.2
1.4
—
—
—
0
0
22
168
1.32
0.55
1.4
1.5
—
—
—
0
0
111
999
1.12
0.53
1.5
1.6
—
—
—
0
0
6
39
1.54
0.53
34.3
5.5
60.67
69.57
mg/l
—
6
30
14
192
0.73
0.52
1.4
1.3
—
—
—
0
0
13
92
1.42
0.50
1.8
1.3
—
—
—
0
0
6
41
1.47
0.50
1.2
1.4
179.50
178.02
mmol/24h
—
6
41
7
45
1.56
0.49
7.4
10.6
—
—
—
0
0
11
76
1.45
0.48
2.5
1.4
0.22
0.32
nmol/l
0.48
11
60
7
47
1.49
0.47
3.0
6.6
—
—
—
0
0
25
200
1.26
0.46
4.4
3.2
3.36
4.29
e9/l
2.14
25
200
8
117
0.68
0.46
1.8
1.6
—
—
—
0
0
25
201
1.25
0.45
4.1
2.6
—
—
—
0
0
15
112
1.34
0.44
1.0
1.1
0.90
1.70
u/ml
—
5
44
12
86
1.40
0.44
1.2
1.2
—
—
—
0
0
19
148
1.29
0.43
1.1
1.1
—
—
—
0
0
27
221
1.23
0.42
1.6
1.4
1.86
48.92
e6/l
1.10
22
177
69
614
1.13
0.42
3.0
3.1
4.66
5.94
e9/l
0.60
60
486
30
249
1.21
0.42
1.1
1.2
—
—
—
0
0
8
58
1.38
0.41
2.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
3.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
1.88
—
0
15
14
105
1.34
0.41
2.5
2.5
1.37
1.83
g/24h
—
5
50
41
352
1.17
0.40
4.1
3.1
0.37
0.24
g/l
0.65
23
146
91
828
1.11
0.39
3.7
3.4
—
—
—
0
0
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
25
206
1.22
0.38
4.4
3.5
54.08
58.06
%
1.09
25
206
5
37
1.35
0.37
1.0
2.3
1426.14
17.66
ug/l
—
5
28
15
116
1.30
0.37
1.4
1.3
—
—
—
0
0
77
698
1.11
0.36
1.6
1.4
—
—
—
0
0
73
806
0.90
0.36
4.1
3.9
—
—
—
0
0
6
43
1.40
0.35
4.7
2.9
—
—
—
0
0
18
146
1.24
0.32
2.8
2.0
10645.04
4623.87
u/l
—
7
57
30
257
1.17
0.32
1.3
1.2
—
—
—
0
0
13
101
1.29
0.31
1.2
1.2
—
—
—
0
0
7
56
1.25
0.29
1.3
1.2
140.86
147.16
nmol/l
—
7
56
8
106
0.75
0.29
2.8
2.3
—
—
—
0
0
45
402
1.12
0.29
2.9
3.5
60830.14
3706.45
u/ml
0.46
37
340
8
110
0.73
0.29
1.0
1.2
—
—
—
0
0
108
1015
1.07
0.25
1.8
2.2
94.61
134.14
ug/g
1.35
79
820
9
72
1.25
0.25
3.9
1.9
—
—
—
0
0
9
74
1.22
0.25
1.3
1.5
—
—
—
0
0
9
75
1.20
0.25
1.1
1.0
239.78
252.35
ng/l
—
9
40
9
76
1.19
0.24
1.3
1.4
—
—
—
0
0
91
971
0.93
0.24
8.3
4.3
—
—
—
0
0
18
212
0.85
0.24
1.8
1.9
184.67
214.40
pmol/l
1.10
18
201
20
172
1.17
0.22
3.3
2.4
—
—
—
0
0
5
42
1.19
0.21
1.2
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
219.17
—
0
6
26
230
1.13
0.20
4.0
5.7
2.56
2.62
mmol/l
0.04
17
156
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
16
136
1.18
0.20
1.8
2.2
92.03
89.32
%
1.78
16
136
86
812
1.06
0.19
2.1
2.1
12.46
12.85
nmol/l
0.18
76
730
6
52
1.15
0.19
1.0
1.0
—
—
—
0
0
17
196
0.87
0.18
1.4
1.7
—
—
—
0
0
12
143
0.84
0.18
2.3
2.6
—
—
—
0
0
7
59
1.19
0.18
1.0
1.2
34.13
35.10
mmol/l
—
7
50
5
66
0.76
0.17
1.6
2.2
—
—
—
0
0
5
67
0.75
0.17
1.6
1.3
148.32
157.66
pmol/l
—
5
67
5
68
0.73
0.17
1.4
1.3
—
—
—
0
0
10
120
0.83
0.16
1.2
1.1
—
—
—
0
0
176
1705
1.04
0.16
1.4
1.5
2.70
2.59
g/l
0.29
119
1022
40
370
1.08
0.16
1.0
1.1
—
—
—
0
0
17
149
1.14
0.15
1.3
1.6
—
—
—
0
0
193
1874
1.04
0.15
1.2
1.2
0.79
1.66
u/ml
1.97
60
496
16
140
1.14
0.15
5.7
5.1
348.25
361.98
umol/l
0.18
16
129
41
381
1.08
0.15
1.9
1.7
—
—
—
0
0
11
93
1.18
0.14
1.8
1.6
—
—
—
0
0
7
90
0.78
0.14
1.1
1.9
—
—
—
0
0
46
431
1.07
0.14
6.7
4.6
—
—
—
0
0
63
598
1.06
0.13
1.4
1.3
—
—
—
0
0
140
1358
1.04
0.12
1.2
1.2
—
—
—
0
0
10
85
1.18
0.12
1.2
1.1
—
—
—
0
0
34
317
1.07
0.12
6.3
4.1
3.98
3.94
mmol/l
0.24
34
312
16
143
1.12
0.11
1.1
1.1
1.51
1.53
g/l
0.08
16
127
23
250
0.92
0.11
3.5
3.6
—
—
—
0
0
13
146
0.89
0.10
6.6
5.9
12.60
11.84
mg/l
0.47
13
135
12
106
1.13
0.09
1.1
1.2
—
—
—
0
0
75
723
1.04
0.09
1.4
1.4
—
—
—
0
0
30
281
1.07
0.09
1.6
1.6
—
—
—
0
0
18
196
0.92
0.09
1.4
1.7
—
—
—
0
0
18
196
0.92
0.09
1.4
1.7
—
—
—
0
0
6
55
1.09
0.09
1.7
2.5
—
—
—
0
0
18
195
0.92
0.08
1.4
1.7
—
—
—
0
0
22
205
1.07
0.08
1.9
1.8
9.80
4.97
iu/l
—
7
61
103
1056
0.97
0.07
1.3
1.3
—
—
—
0
0
19
176
1.08
0.07
1.4
1.6
—
—
—
0
0
8
78
1.03
0.07
1.5
1.4
—
—
—
0
0
8
78
1.03
0.07
1.8
1.3
—
—
—
0
0
8
94
0.85
0.06
2.1
3.5
—
—
—
0
0
10
111
0.90
0.06
1.5
1.4
—
—
—
0
0
45
436
1.03
0.05
2.6
2.7
—
—
—
0
0
17
160
1.06
0.04
1.6
1.4
—
—
—
0
0
17
180
0.94
0.04
1.4
1.8
—
—
—
0
0
54
553
0.98
0.04
1.1
1.2
131.04
158.95
iu/ml
0.20
19
222
91
898
1.01
0.02
1.3
1.5
—
—
—
0
0
123
1241
0.99
0.02
1.3
1.3
—
—
—
0
0
233
2326
1.00
0.00
3.4
3.0
0.71
0.77
ug/l
0.74
158
1553
13
129
1.01
0.00
1.7
2.2
—
—
—
0
0
19
195
0.97
0.00
1.2
1.4
209.55
189.22
miu/ml
—
9
83
10
95
1.05
0.00
1.7
2.2
—
—
—
0
0
0
9
0.00
0.00
0.0
3.1
—
—
—
0
0
5
50
1.00
0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
7
74
0.95
0.00
1.1
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
8.63
—
0
6
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
-0.00
1.0
1.1
—
—
—
0
0
7
76
0.92
-0.00
1.4
1.4
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.1
—
—
—
0
0
10
100
1.00
-0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
403.14
—
0
7
5
54
0.93
-0.00
1.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.0
—
—
—
0
0
7
79
0.89
-0.00
1.1
1.0
273.43
286.88
mg/l
—
7
67
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
34.26
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
8.56
—
0
5
6
60
1.00
-0.00
2.2
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.80
—
0
5
7
75
0.93
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
-0.00
1.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_RETINALDETACHOTH and mortality.

Females

Parameter HR [95% CI] p-value
H7_RETINALDETACHOTH 1.211 [1.03, 1.42] 0.018
Birth year 0.992 [0.98, 1.0] 0.08

During the follow-up period (1.1.1998 — 31.12.2019), 411 out of 2315 females with H7_RETINALDETACHOTH died.

Males

Parameter HR [95% CI] p-value
H7_RETINALDETACHOTH 1.138 [0.98, 1.33] 0.096
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 492 out of 2585 males with H7_RETINALDETACHOTH died.

Mortality risk

Mortality risk for people of age

years, who have H7_RETINALDETACHOTH.

N-year risk Females Males
1 0.104% 0.207%
5 0.699% 1.414%
10 1.675% 3.391%
15 3.173% 6.485%
20 5.648% 10.842%

Relationships between endpoints

Index endpoint: H7_RETINALDETACHOTH – Other, unspecified and serous retinal detachments

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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