cardiovascular disease: A disease involving the cardiovascular system.
Other other unspecified disorders of the circulatory system
DOID EFO Endpoint Browser PheWeb
I9_OTHOTH
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1336 |
4. Check minimum number of eventsNone |
1336 |
5. Include endpointsNone |
1336 |
6. Filter based on genotype QC (FinnGen only) |
1336 |
Control definitions (FinnGen only)
- Control exclude
- I9_OTH
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Other other unspecified disorders of the circulatory system
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8785 | 4639 | 4036 |
| Only index persons | 6572 | 3616 | 2956 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.13 | 0.11 |
| Only index persons | 0.12 | 0.13 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 62.77 | 62.32 | 63.22 |
| Only index persons | 60.58 | 59.70 | 61.65 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1336 | 717 | 619 |
| Unadjusted period prevalence (%) | 0.26 | 0.24 | 0.27 |
| Median age at first event (years) | 59.75 | 57.66 | 62.18 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1197
- Matched controls
- 11971
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I97.0
ICD-10 Finland
Postcardiotomy syndrome
+∞
323.0
484
*
I97.2
ICD-10 Finland
Postmastectomy lymphoedema syndrome
429.7
323.0
339
11
115
Kela drug reimbursment
Breast cancer
8.1
124.6
311
498
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
12.8
123.1
231
220
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
14.1
117.1
209
177
HAC20
NOMESCO Finland
Total mastectomy
11.9
107.5
208
208
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
7.7
99.6
253
404
I99
ICD-10 Finland
Other and unspecified disorders of circulatory system
359.0
98.5
98
*
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
9.1
92.5
207
268
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
7.5
88.6
227
363
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
14.6
88.0
153
119
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
8.1
85.5
206
299
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
27.7
85.3
118
47
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.8
83.8
468
1743
PJ1AN
NOMESCO Finland
Lymphsystem isotope imaging
213.9
78.2
80
*
B01AA03
ATC
warfarin; systemic
3.6
77.9
463
1790
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
6.9
74.5
200
337
H02AB02
ATC
dexamethasone; systemic
4.9
74.2
274
681
I97.1
ICD-10 Finland
Other functional disturbances following cardiac surgery
+∞
73.7
70
*
C03CA01
ATC
furosemide; systemic
3.1
72.0
562
2625
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
71.6
721
3997
HA1AA
NOMESCO Finland
X-ray mammography
5.8
71.4
222
452
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
5.2
69.3
240
553
WX872
NOMESCO Finland
Intensive care
6.9
68.1
181
299
L02BA01
ATC
tamoxifen; oral
8.5
65.3
150
198
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
7.6
64.3
160
239
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.6
61.9
339
1189
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
6.5
58.9
164
286
PJW99
NOMESCO Finland
Other operation on lymphatic system
48.6
57.0
69
15
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
300.4
56.7
57
*
ZZQ70
NOMESCO Finland
Free microvascular graft of lymph nodes
562.5
55.0
54
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.0
53.8
396
1692
B01AB05
ATC
enoxaparin; parenteral
2.7
53.2
505
2530
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
13.3
52.2
93
75
AN1
HP
Coronary angiography
3.6
51.9
274
918
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
18.7
50.9
79
45
QCJ00
NOMESCO Finland
Liposuction in upper limb
266.1
50.5
51
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.9
48.9
366
1566
TPH07
NOMESCO Finland
Cathetrisation of artery
3.7
48.6
237
740
L02BG04
ATC
letrozole; oral
5.2
48.0
159
340
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.8
48.0
411
1908
A04AA02
ATC
granisetron; systemic, transdermal
5.1
47.5
160
349
81
HP
Angiography of the heart and coronary arteries
4.7
47.2
175
423
I89.0
ICD-10 Finland
Lymphoedema, not elsewhere classified
28.8
46.5
63
23
TQW20
NOMESCO Finland
Tatoe
20.3
45.8
69
36
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.9
45.5
332
1386
WW502
NOMESCO Finland
Autotransfusion
34.4
45.5
59
18
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
25.0
45.4
64
27
I35.0
ICD-10 Finland
Aortic (valve) stenosis
4.6
45.0
168
408
11
HP
Coronary artery bypass surgery
9.5
43.6
92
104
A04AD12
ATC
aprepitant; systemic
11.7
43.4
82
75
X76
ICPC
Malignant neoplasm breast female
11.7
42.9
81
74
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
5.1
41.7
140
303
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
41.5
425
2149
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
6.8
40.9
108
173
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
12.5
40.0
73
62
C50.99
ICD-10 Finland
Breast, unspecified
7.2
39.7
100
150
C50
ICD-10 Finland
Malignant neoplasm of breast
8.3
39.4
90
116
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.7
39.4
342
1565
A46
ICD-10 Finland
Erysipelas
3.0
39.3
259
998
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
10.2
39.2
79
82
H02AB06
ATC
prednisolone; systemic
2.2
38.7
651
4160
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
6.3
37.4
103
175
45899
ICD-8 Finland
Other disease of circulatory system, Other and unspecified circulatory disease
+∞
36.6
35
*
C07AB07
ATC
bisoprolol; oral
2.2
35.9
673
4456
K83
ICPC
Heart valve disease NOS
14.7
34.9
59
42
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
4.4
34.7
134
334
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
19.7
33.7
51
27
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
10.1
33.1
67
70
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
8.3
32.7
74
94
L03AA13
ATC
pegfilgrastim; parenteral
5.5
32.6
101
198
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
10.1
32.6
66
69
NK6AN
NOMESCO Finland
Total body bone isotope imaging
6.3
32.5
89
150
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
7.0
32.4
82
124
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
11.9
32.3
60
53
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.3
31.9
381
2022
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
16.1
31.4
51
33
I97.9
ICD-10 Finland
Postprocedural disorder of circulatory system, unspecified
+∞
31.4
30
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.9
31.3
138
388
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
7.7
31.1
74
102
I97.8
ICD-10 Finland
Other postprocedural disorders of circulatory system, not elsewhere classified
+∞
30.3
29
*
C01DA14
ATC
isosorbide mononitrate; oral
2.5
30.3
279
1294
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
5.9
30.3
87
156
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
8.2
30.0
68
87
I50.9
ICD-10 Finland
Heart failure, unspecified
2.6
29.9
247
1077
I34.1
ICD-10 Finland
Mitral (valve) prolapse
6.5
29.5
79
129
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
10.1
29.4
59
61
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
6.4
29.2
79
131
FNC30
NOMESCO Finland
Aorto-coronary venous bypass with three distal anastomoses
7.7
28.4
67
91
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
28.0
466
2830
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
4.9
27.9
94
203
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
27.8
305
1539
C03DA01
ATC
spironolactone; oral
2.9
27.8
191
744
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
30.9
27.3
36
12
HAE99
NOMESCO Finland
Other reconstruction of breast
18.1
27.2
42
24
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
26.8
130
394
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
26.6
193
774
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
19.1
25.8
39
21
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
3.1
25.6
154
547
WX402
NOMESCO Finland
General anaesthesia
2.4
25.6
244
1143
1CD02
NOMESCO Finland
NA
16.3
25.5
41
26
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.9
25.1
168
641
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
39.7
25.0
31
8
A04AA55
ATC
palonosetron, combinations; systemic
5.8
24.6
71
128
61
HP
Catheterization and pressure measurement of the left side of the heart
7.1
24.6
61
90
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
7.7
24.3
57
77
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.8
24.2
84
187
I50.0
ICD-10 Finland
Congestive heart failure
3.0
24.2
147
526
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
24.2
302
1603
45898
ICD-8 Finland
Other disease of circulatory system, Alii definiti
+∞
24.0
23
*
4590A
ICD-9 Finland
Other disorders of circulatory system, Haemorrhage, unspecified
+∞
24.0
23
*
J01DB01
ATC
cefalexin; oral
2.1
24.0
961
7923
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
5.1
23.9
77
158
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
23.9
142
500
PJA12
NOMESCO Finland
Sentinel node biopsy
3.1
23.8
140
490
ZX120
NOMESCO Finland
Intravenous
2.8
23.8
162
625
TFP20
NOMESCO Finland
Cardiodefibrillation
3.1
23.7
140
492
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.6
23.6
185
774
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
5.0
23.5
77
161
HAB40
NOMESCO Finland
Wedge excision of mammary gland
3.8
23.3
104
294
A02BC02
ATC
pantoprazole; systemic
1.9
23.2
800
6185
4598X
ICD-9 Finland
Other disorders of circulatory system, Other specified disorders of circulatory system
+∞
23.0
22
*
L02BG06
ATC
exemestane; oral
8.8
22.7
49
58
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.1
22.7
317
1758
ZX080
NOMESCO Finland
Image guided radiotherapy
6.6
22.2
58
92
L03AA14
ATC
lipegfilgrastim; parenteral
7.4
22.2
53
74
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
6.3
22.0
59
97
4599X
ICD-9 Finland
Other disorders of circulatory system, Unspecified circulatory system disorder
+∞
21.9
21
*
Z31.5
ICD-10 Finland
Genetic counselling
4.3
21.6
83
205
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
8.5
21.5
47
57
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
21.4
206
958
AA1
HP
Conventional CABG
6.0
21.4
60
105
JN4BD
NOMESCO Finland
Extensive body CT
2.5
21.2
177
766
R50.9
ICD-10 Finland
Fever, unspecified
2.4
21.1
204
954
ZZF00
NOMESCO Finland
Graft of adipose tissue
13.7
21.1
36
27
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.3
20.8
109
350
ZSZ10
NOMESCO Finland
Secondary repair operation
213.4
20.6
21
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
20.5
352
2108
N02AX02
ATC
tramadol; systemic, rectal
1.8
20.5
537
3722
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
14.5
20.4
34
24
J01MA12
ATC
levofloxacin; systemic
2.1
20.4
269
1449
Q23.11
ICD-10 Finland
Bicuspid aortic valve
11.2
20.2
38
35
PD5BD
NOMESCO Finland
Extensive CT of aorta
6.1
20.1
55
93
I25.2
ICD-10 Finland
Old myocardial infarction
2.9
20.1
129
477
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
20.0
171
749
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
6.9
20.0
50
75
FL1AC
NOMESCO Finland
Left cardioangiography
6.9
20.0
50
75
TQB05
NOMESCO Finland
Puncture of skin of trunk
13.4
19.8
34
26
WX704
NOMESCO Finland
Intubation
3.1
19.7
116
404
AC4
HP
MVP
19.8
19.6
29
15
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.8
18.9
403
2589
C01BD01
ATC
amiodarone; systemic
4.4
18.8
70
168
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
5.8
18.7
53
94
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
9.1
18.7
39
44
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
24.1
18.7
26
11
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.2
18.7
73
184
I20.09
ICD-10 Finland
Unstable angina
3.1
18.5
106
364
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.3
18.3
94
298
C07AB02
ATC
metoprolol; systemic
1.9
18.2
305
1797
I20.01
ICD-10 Finland
Unstable angina
4.1
18.2
71
179
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
8.0
18.1
41
53
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
6.9
18.1
45
67
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.0
18.0
109
388
L09
ICPC
Arm symptom/complaint
4.0
17.3
71
187
R06.0
ICD-10 Finland
Dyspnoea
1.9
17.3
323
1971
A08
ICPC
Swelling
3.5
17.3
83
250
I95.1
ICD-10 Finland
Orthostatic hypotension
7.3
17.2
41
58
AB2
HP
AVR bio, stent
8.4
17.0
37
45
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
6.5
17.0
44
70
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.7
16.7
118
463
K78
ICPC
Atrial fibrillation/flutter
2.6
16.5
126
517
R4110
NOMESCO Finland
Physiotherapy
1.8
16.4
343
2170
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
16.4
460
3191
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
11.4
16.3
30
27
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
24.8
16.0
22
9
HA3AT
NOMESCO Finland
Pucture of mammary gland cyst with ultrasound examination
15.9
15.7
25
16
AB1
HP
AVR mechanical
17.5
15.6
24
14
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
3.1
15.6
90
310
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
4.9
15.6
51
108
XF402
NOMESCO Finland
ECG with work load test
2.3
15.5
161
772
N02BE01
ATC
paracetamol; systemic, rectal
1.9
15.4
1003
8785
C01AA05
ATC
digoxin; systemic
2.4
15.4
136
604
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
8.4
15.3
33
40
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
12.6
14.9
26
21
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
5.2
14.8
46
92
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
10.6
14.7
28
27
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
13.4
14.7
25
19
62
HP
Catheterization and pressure measurement of the right side of the heart
18.6
14.7
22
12
FEC00
NOMESCO Finland
Pericardiopleurostomy
+∞
14.6
14
*
I50.1
ICD-10 Finland
Left ventricular failure
3.1
14.6
82
276
I30.9
ICD-10 Finland
Acute pericarditis, unspecified
14.4
14.6
24
17
ZZR10
NOMESCO Finland
Flap of skin and muscle
11.0
14.5
27
25
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.8
14.5
315
2004
PJW20
NOMESCO Finland
Lymphovenous shunt
151.7
14.5
15
*
WX892
NOMESCO Finland
Monitored bed care
2.5
14.4
114
477
K84
ICPC
Heart disease other
4.5
14.4
51
118
SPAT1263
SPAT
Sampling
1.6
14.3
494
3589
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
11.5
14.3
26
23
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
14.2
184
974
TQW11
NOMESCO Finland
Vacuum treatment of wound
5.4
14.1
42
80
L02BG03
ATC
anastrozole; oral
5.9
14.1
39
68
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
12.1
14.1
25
21
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
14.6
14.1
23
16
XF404
NOMESCO Finland
Ambulatory ECG
2.3
14.0
135
624
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.2
14.0
75
246
AA1AD
NOMESCO Finland
CT of head and brain
1.8
14.0
312
1998
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
13.9
365
2455
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.8
13.9
89
328
XX3DW
NOMESCO Finland
Time consuming IT work
2.2
13.8
143
683
XFE00
NOMESCO Finland
Epicardial ultrasonography
4.3
13.8
51
123
J01FF01
ATC
clindamycin; systemic
1.7
13.8
323
2097
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
9.8
13.7
27
28
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.2
13.7
42
83
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
13.6
259
1572
I98.2
ICD-10 Finland
Oesophageal varices without bleeding in diseases classified elsewhere
+∞
13.6
13
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
5.7
13.5
38
68
207
Kela drug reimbursment
Chronic arrhythmias
1.9
13.5
208
1174
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.7
13.3
94
370
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
13.0
354
2396
111
HP
Conventional CABG
8.2
12.8
28
35
J01CE08
ATC
benzathine benzylpenicillin; parenteral
7.6
12.7
29
39
WZC30
NOMESCO Finland
Teaching
2.0
12.6
174
938
XF640
NOMESCO Finland
NA
3.4
12.6
60
181
PD5AD
NOMESCO Finland
CT of aorta
5.8
12.6
35
62
45891
ICD-8 Finland
Other disease of circulatory system, Haemorrhagia subcutanea NUD
+∞
12.5
12
*
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
7.4
12.5
29
40
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.3
12.4
117
533
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
11.8
12.3
22
19
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
12.2
210
1232
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
5.3
12.2
36
69
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
7.3
12.0
28
39
R60.0
ICD-10 Finland
Localized oedema
2.0
12.0
152
793
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
12.0
85
333
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.3
11.9
60
189
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.5
11.9
95
400
I71.00
ICD-10 Finland
Dissecting aneurysm of aorta (ruptured) [any part]
14.8
11.8
19
13
FM1FN
NOMESCO Finland
Heart function isotope examination
16.6
11.7
18
11
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
11.6
117
552
AA2
HP
Off pump CABG sternotomy
9.4
11.5
23
25
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
6.8
11.5
28
42
C50.10
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, no histological veryfication
13.8
11.5
19
14
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
11.4
108
493
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
6.4
11.4
29
46
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
11.3
217
1315
QC9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in upper extremities, unspecified
35.4
11.3
14
*
S18
ICPC
Laceration/cut
1.5
11.3
481
3624
XX1XN
NOMESCO Finland
Other isotope examination
7.4
11.3
26
36
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
4.8
11.2
36
76
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
17.2
11.2
17
10
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.2
11.2
41
99
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
5.0
11.2
35
72
D70.82
ICD-10 Finland
Drug-induced neutropenia
5.0
11.2
35
72
QBJ00
NOMESCO Finland
Liposuction in trunk
12.8
11.1
19
15
FKD00
NOMESCO Finland
Replacement of mitral valve using mechanical prosthesis
25.3
11.1
15
6
FWW96
NOMESCO Finland
Other reoperation on heart or major thoracic vessels
20.2
11.1
16
8
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
11.0
207
1247
HAD99
NOMESCO Finland
Other plastic operation on breast
9.3
11.0
22
24
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
6.7
11.0
27
41
A02BC01
ATC
omeprazole; systemic
1.6
11.0
333
2304
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
4.7
11.0
36
78
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
43.7
10.9
13
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
5.8
10.9
30
53
SPAT1153
SPAT
Removal of sutures
1.6
10.9
381
2730
SPAT1229
SPAT
Assessment of need for aid
2.2
10.8
114
550
C50.20
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,no histological veryfication
10.7
10.8
20
19
I31.8
ICD-10 Finland
Other specified diseases of pericardium
28.3
10.7
14
5
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.9
10.7
34
71
HWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of mammary gland
21.7
10.7
15
7
AJ2
HP
Reconstruction of the ascending aorta
21.7
10.7
15
7
N03AX16
ATC
pregabalin; oral
1.7
10.7
272
1793
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
10.5
500
3846
B01AC04
ATC
clopidogrel; oral
1.8
10.3
204
1246
J01MA02
ATC
ciprofloxacin; systemic
1.5
10.3
443
3327
HA1CM
NOMESCO Finland
Mammary gland extensive MRI examination with 3 Tesla magnet
23.6
10.2
14
6
GD1AD
NOMESCO Finland
Thorax CT examination
2.9
10.2
63
227
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
6.3
10.2
26
42
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.9
10.1
32
67
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.3
10.1
94
427
A02BC05
ATC
esomeprazole; systemic
1.5
10.0
464
3532
SPAT1097
SPAT
Recording of ECG
1.8
10.0
187
1122
JN4AD
NOMESCO Finland
Body CT examination
2.2
10.0
108
525
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
10.0
378
2747
FCA70
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of biological valve prosthesis and tube graft
16.8
9.9
15
9
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
4.5
9.9
34
78
WX720
NOMESCO Finland
Own respiration
3.0
9.8
57
199
B01AC06
ATC
acetylsalicylic acid; oral (platelet aggregation inhibitors excl. heparin)
2.9
9.8
58
206
A04AA01
ATC
ondansetron; systemic, rectal
2.4
9.8
85
375
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
9.6
9.8
19
20
J01CA04
ATC
amoxicillin; systemic
1.5
9.7
877
7681
C10AA05
ATC
atorvastatin; oral
1.5
9.5
450
3432
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
15.2
9.5
15
10
SPAT1262
SPAT
Handing over of treatment supplies
1.7
9.5
215
1367
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
9.4
290
2000
21
HP
Aortic Valve Replacement (AVR)
30.2
9.4
12
*
B01AB10
ATC
tinzaparin; parenteral
2.2
9.4
92
428
I95.9
ICD-10 Finland
Hypotension, unspecified
12.4
9.4
16
13
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.5
9.3
72
298
C50.80
ICD-10 Finland
Overall malignant tumor of the mammary gland, no histological veryfication
13.8
9.2
15
11
ZSH00
NOMESCO Finland
Procedure related to previous procedure classified in chapter H
13.8
9.2
15
11
ZXA05
NOMESCO Finland
Left side
1.6
9.2
310
2188
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
9.1
287
1992
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
5.2
9.1
27
53
R4120
NOMESCO Finland
Occupational therapy
2.3
9.1
80
355
C09AA05
ATC
ramipril; oral
1.6
9.0
290
2018
HAD40
NOMESCO Finland
Mastopexy
10.1
9.0
17
17
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
10.1
9.0
17
17
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
6.6
9.0
22
34
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.1
8.9
23
38
HAD00
NOMESCO Finland
Augmentation mammoplasty
24.2
8.9
12
5
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
3.6
8.9
39
112
N05CF01
ATC
zopiclone; oral
1.5
8.9
378
2807
K99
ICPC
Cardiovascular disease other
3.1
8.9
46
150
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
8.9
180
1106
A11
ICPC
Chest pain NOS
2.2
8.9
93
447
N63
ICD-10 Finland
Unspecified lump in breast
2.5
8.8
70
295
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
8.7
120
648
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
8.7
200
1273
SPAT1254
SPAT
Administration of medicine
1.7
8.6
171
1043
AP1
HP
Catheterization of the left side of the heart
4.1
8.6
32
80
A06AD11
ATC
lactulose; oral
1.7
8.5
185
1159
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
10.1
8.5
16
16
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
8.5
129
719
ZXA00
NOMESCO Finland
Right side
1.5
8.5
322
2331
SPAT1211
SPAT
Application of soft bandage
2.0
8.4
114
611
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
8.4
46
156
K76
ICPC
Ischaemic heart dis without angina
3.1
8.4
44
145
FEC01
NOMESCO Finland
Thoracoscopic pericardiopleurostomy
+∞
8.3
8
*
C10AA01
ATC
simvastatin; oral
1.4
8.3
513
4097
FNC40
NOMESCO Finland
Aorto-coronary venous bypass with four distal anastomoses
6.3
8.3
21
34
FNE20
NOMESCO Finland
Coronary bypass using free arterial graft of radial artery
8.6
8.3
17
20
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
10.8
8.3
15
14
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
10.8
8.3
15
14
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
9.5
8.3
16
17
SPAT1301
SPAT
No procedures
1.5
8.3
356
2647
C50.00
ICD-10 Finland
Malignant tumor of nipple and areola, no histological veryfication
6.5
8.2
20
31
M10.9
ICD-10 Finland
Gout, unspecified
2.2
8.1
84
403
X21
ICPC
Breast sympt/compl female other
4.4
8.1
28
65
Z50.0
ICD-10 Finland
Cardiac rehabilitation
4.7
8.1
26
56
C07AA07
ATC
sotalol; systemic
2.6
8.1
59
237
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
8.2
8.1
17
21
PD1AD
NOMESCO Finland
CT of abdominal aorta and branches
11.8
8.1
14
12
8500/3-C50.8
ICD-O-3
Infiltrating duct carcinoma, NOS, of overlapping lesion of breast
11.8
8.1
14
12
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
17.3
8.1
12
7
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.1
8.1
92
459
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.4
8.1
37
111
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
2.4
8.0
65
278
M04AA01
ATC
allopurinol; systemic
1.7
8.0
164
1012
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
8.0
468
3695
SPAT1310
SPAT
Counselling related to known health issue
1.5
7.9
342
2539
C77.3
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Axillary and upper limb lymph nodes
13.1
7.9
13
10
L12
ICPC
Hand/finger symptom/complaint
1.8
7.9
148
886
S76
ICPC
Skin infection other
2.4
7.8
66
286
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
7.8
151
911
L03AA02
ATC
filgrastim; parenteral
3.3
7.8
37
114
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
7.8
131
759
J01DA01
ATC
[U] cefalexin; systemic
1.4
7.8
682
5789
N02AA05
ATC
oxycodone; systemic
1.7
7.8
172
1084
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
7.0
7.8
18
26
TK800
NOMESCO Finland
Hemodialysis
3.4
7.8
36
109
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.3
7.7
69
310
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.0
7.7
94
482
FKC96
NOMESCO Finland
Other repair of mitral valve for insufficiency
15.1
7.7
12
8
HA1BG
NOMESCO Finland
MRI examination of mammary gland with high intensity magnet
7.5
7.7
17
23
R02
ICPC
Shortness of breath/dyspnoea
1.8
7.6
138
818
211
HP
AVR mechanical
18.5
7.6
11
6
B29
ICPC
Lymph/immune mech sympt/complt other
8.1
7.6
16
20
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
11.9
7.6
13
11
23
HP
Mitral valve plasty
25.2
7.6
10
*
C50.89
ICD-10 Finland
Overall malignant tumor of the mammary gland, other or undeterminated histology
6.2
7.5
19
31
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
10.1
7.5
14
14
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
2.4
7.5
62
268
9707
FHL
Ablation of mammae and removal of axillary lymph nodes
7.2
7.5
17
24
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
7.4
270
1925
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
7.4
56
232
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
5.1
7.4
22
44
N06AX16
ATC
venlafaxine; oral
1.8
7.4
129
756
SPAT1255
SPAT
Intravenous administration of medicine
2.1
7.3
79
388
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
4.4
7.3
25
58
C50.9
ICD-10 Finland
Malignant neoplasm: Breast, unspecified
8.4
7.3
15
18
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
10.9
7.3
13
12
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
5.0
7.3
22
45
SPAT1312
SPAT
General health counselling
1.5
7.3
332
2485
WX110
NOMESCO Finland
Local anesthesy
1.4
7.3
706
6068
71798
ICD-8 Finland
Other nonarticular rheumatism, Other muscular rheumatism, fibrositis and myalgia
6.3
7.2
18
29
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
2.8
7.2
43
156
H02AB07
ATC
prednisone; oral
1.7
7.1
159
1001
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.8
7.1
118
680
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
6.6
7.1
17
26
WX002
NOMESCO Finland
Sedation and analgesia
1.6
7.1
222
1529
1501
Kela drug reimbursment
Palbociclib
8.0
7.1
15
19
S97
ICPC
Chronic ulcer skin
2.2
7.1
67
311
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
4.7
7.0
22
47
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
7.0
307
2280
WX882
NOMESCO Finland
High dependency care
2.6
6.9
46
178
C07AG02
ATC
carvedilol; oral
2.0
6.9
82
420
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
13.9
6.9
11
8
E0000UV
ATC
NA
1.4
6.9
409
3213
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
6.9
86
450
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.4
6.9
23
53
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
6.8
299
2216
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
6.8
379
2939
C10AX09
ATC
ezetimibe; oral
1.8
6.8
122
719
I44.2
ICD-10 Finland
Atrioventricular block, complete
2.8
6.8
40
144
XFN00
NOMESCO Finland
Inside imaging of coronary arteries??
6.1
6.8
17
28
A40.8
ICD-10 Finland
Other streptococcal sepsis
6.1
6.8
17
28
WX725
NOMESCO Finland
Noninvasive ventilation
2.4
6.8
55
238
PG1BD
NOMESCO Finland
Extensive CT angiography of tissue graft, e.g. assessment of TRAN graft
40.3
6.8
8
*
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.7
218
1513
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
3.7
6.7
27
74
C10AA03
ATC
pravastatin; oral
1.9
6.7
92
495
I30.0
ICD-10 Finland
Acute nonspecific idiopathic pericarditis
22.6
6.7
9
*
I20.00
ICD-10 Finland
Unstable angina
2.5
6.7
50
206
L04
ICPC
Chest symptom/complaint
2.2
6.6
64
299
394
Kela drug reimbursment
Palbociclib
7.8
6.6
14
18
Q21.10
ICD-10 Finland
Persistent ostium secundum
7.8
6.6
14
18
FXZ00
NOMESCO Finland
Off-pump cardiac operation
5.5
6.6
18
33
127
Kela drug reimbursment
Transplant complication
3.9
6.6
25
65
Z95.9
ICD-10 Finland
Presence of cardiac and vascular implant and graft, unspecified
12.3
6.6
11
9
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.5
6.6
223
1564
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
6.6
274
2006
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
8.7
6.6
13
15
R18
ICD-10 Finland
Ascites
3.4
6.5
29
87
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
6.4
76
386
AC1
HP
MVR mechanical
70.2
6.4
7
*
I33.9
ICD-10 Finland
Acute endocarditis, unspecified
14.4
6.4
10
7
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.0
6.4
80
418
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.4
373
2914
NK6AQ
NOMESCO Finland
Whole body bone SPET with low dose CT
8.2
6.3
13
16
I47.2
ICD-10 Finland
Ventricular tachycardia
3.2
6.3
30
94
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
6.3
104
599
FKC60
NOMESCO Finland
Resection and reconstruction of leaflet of mitral valve for insufficiency
11.1
6.3
11
10
HA2AT
NOMESCO Finland
Cytology of mammary gland with ultrasound guidance
11.1
6.3
11
10
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
3.9
6.3
24
63
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
9.3
6.3
12
13
72800
ICD-8 Finland
Vertebrogenic pain syndrome, Cervicalgia
9.3
6.3
12
13
C50.52
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, lobular tumor
9.3
6.3
12
13
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
18.1
6.3
9
5
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
18.1
6.3
9
5
FEB51
NOMESCO Finland
Thoracoscopic pericardiotomy
+∞
6.3
6
*
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
3.2
6.2
30
95
AQ1
HP
Conventional electrophysiological examination
4.8
6.2
19
40
HAD20
NOMESCO Finland
Liposuction of breast
26.8
6.2
8
*
Z40.0
ICD-10 Finland
Prophylactic surgery for risk-factors related to malignant neoplasms
26.8
6.2
8
*
I71.09
ICD-10 Finland
Aortic dissection [regardless of location]
7.1
6.2
14
20
XG410
NOMESCO Finland
Flow-volume spirometry
2.5
6.2
47
195
J01FA06
ATC
roxithromycin; oral
1.4
6.1
430
3459
PB1DE
NOMESCO Finland
Upper extremity arteries ultrasound examination with Doppler method
12.6
6.1
10
8
B04
ICPC
Blood symptom/complaint
8.6
6.1
12
14
WX870
NOMESCO Finland
Other postsurgical intensive care
6.7
6.0
14
21
N19
ICD-10 Finland
Unspecified kidney failure
2.4
6.0
46
192
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
61
27
23.63
84.18
6.9
7.1
—
—
—
0
0
428
1746
3.14
76.31
3.1
2.2
30.5
29.8
s
1.58
414
1691
891
5744
2.65
60.92
9.6
6.4
12.8
12.2
umol/l
0.42
861
5447
786
5017
2.38
51.07
5.2
4.0
—
—
—
0
0
260
998
2.99
49.39
10.5
7.8
9.4
10.2
mmol/l
1.07
248
952
381
1828
2.52
46.45
4.9
3.6
0.8
0.8
mmol/l
0.41
353
1711
830
5649
2.24
43.19
10.6
6.9
1.2
1.2
mmol/l
7.86
689
4767
773
5162
2.18
41.53
9.2
6.2
1.2
1.2
mmol/l
8.14
714
4673
292
1309
2.57
40.46
9.0
8.0
5.1
5.1
kpa
0.16
273
1249
292
1310
2.57
40.39
9.0
7.9
13.7
12.0
kpa
3.65
273
1251
573
3435
2.17
40.28
4.5
3.1
2336.3
1551.2
ng/l
1.16
516
2946
288
1308
2.53
38.67
9.1
8.0
1.2
1.2
mmol/l
0.03
231
1004
242
1012
2.70
38.46
4.7
3.0
273.8
217.6
ng/l
1.00
220
935
247
1062
2.63
37.03
9.9
8.8
114.3
121.2
g/l
5.91
234
1024
171
607
3.08
36.71
11.7
11.5
—
—
—
0
0
462
2623
2.16
36.54
2.9
2.4
—
—
—
0
0
99
258
4.06
34.09
10.9
8.4
105.3
105.4
mmol/l
0.08
87
234
886
6528
2.06
33.18
8.2
4.9
6.8
6.7
mmol/l
0.85
847
6169
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
125
393
3.41
32.69
4.4
2.9
0.3
0.4
u/ml
1.48
84
225
709
4847
1.99
32.64
7.0
4.8
34.2
35.3
g/l
4.93
661
4496
135
471
3.08
29.68
8.9
5.8
1.7
1.6
%
1.53
122
445
175
708
2.69
29.27
11.6
7.5
24.5
24.4
mmol/l
0.10
163
661
1049
8421
2.14
28.61
12.7
7.6
82.4
80.3
u/l
0.78
1014
7892
249
1203
2.31
28.40
3.5
4.1
12.3
24.3
ug/l
0.81
193
996
843
6280
1.93
28.36
11.9
9.1
4.0
4.1
e9/l
1.44
766
5467
288
1488
2.19
27.88
46.9
26.4
1.7
1.3
inr
2.52
40
183
528
3411
1.91
27.30
4.6
3.3
35.0
33.2
u/l
0.40
498
3243
215
991
2.39
27.24
3.2
2.4
13.1
7.2
ug/l
2.28
197
860
292
1541
2.15
26.67
3.6
2.6
21.4
22.5
%
0.61
226
1314
102
329
3.27
25.52
3.2
2.9
90.2
89.7
%
0.07
95
314
301
1636
2.08
25.31
3.5
2.6
2.3
2.3
g/l
0.61
284
1521
287
1535
2.11
25.17
8.9
5.8
1.1
1.0
mmol/l
2.34
267
1408
336
1925
2.00
24.31
2.1
1.8
—
—
—
0
0
370
2193
1.95
24.25
7.0
3.8
989.4
392.2
ng/l
1.27
317
1785
313
1779
1.99
23.01
3.6
2.6
11.7
12.8
umol/l
1.92
296
1650
158
700
2.43
21.65
4.9
3.4
120.8
127.9
g/l
3.65
143
685
121
476
2.70
21.21
2.4
2.0
1.4
1.9
ug/l
0.24
99
421
605
4317
1.73
20.88
5.1
3.7
49.5
55.2
ng/l
0.20
468
3127
551
3842
1.74
20.57
5.0
3.5
2.3
2.4
mmol/l
1.38
489
3336
93
326
2.99
20.18
2.1
1.6
—
—
—
0
0
499
3416
1.74
19.67
3.3
2.5
57.4
57.5
u/l
0.03
460
3150
232
1282
1.98
18.10
3.3
4.3
285.6
248.6
u/l
2.29
225
1209
56
153
3.78
18.04
6.1
6.8
10.5
11.8
mg/l
1.13
49
141
489
3417
1.68
17.35
2.7
2.2
232.3
237.8
u/l
0.05
463
3202
425
2872
1.70
17.03
2.9
2.2
3.0
3.1
mg/l
0.22
376
2437
360
2341
1.74
16.51
2.2
1.8
1.3
1.2
mg/l
0.20
278
1815
233
1336
1.90
16.17
2.8
2.6
1.9
1.8
%
0.46
209
1196
76
281
2.81
14.99
1.1
1.2
—
—
—
0
0
114
519
2.31
14.58
1.6
1.9
1.4
1.5
g/l
0.27
92
454
44
121
3.73
14.08
1.8
1.3
122112.2
122617.5
e6/l
0.00
32
73
865
7167
1.59
14.01
5.8
4.6
835.9
2571.9
e6/l
0.81
15
104
228
1355
1.82
13.99
2.0
1.7
—
—
—
0
0
69
255
2.80
13.63
4.5
2.9
34.5
34.8
umol/l
0.03
62
217
233
1409
1.79
13.46
8.1
7.2
104.5
104.3
mmol/l
0.19
227
1376
226
1357
1.80
13.37
2.0
1.7
—
—
—
0
0
94
409
2.40
13.33
2.9
2.3
552.1
485.7
ug/l
0.10
86
383
138
705
2.07
13.23
8.9
9.9
94.9
93.8
%
1.77
138
698
40
109
3.75
12.98
1.4
1.3
0.2
0.3
nmol/l
0.22
26
75
200
1182
1.81
12.42
4.5
3.4
—
—
—
0
0
189
1101
1.83
12.29
5.5
4.0
2.1
1.9
mmol/l
0.19
146
863
135
706
2.01
12.13
9.0
9.8
0.8
0.7
%
2.57
135
700
45
141
3.27
11.85
1.8
1.3
1326.4
1772.1
e6/l
0.56
36
99
578
4487
1.51
11.80
3.8
2.8
165.7
137.9
ug/l
1.32
532
4106
188
1108
1.81
11.75
5.4
4.0
5.9
5.8
kpa
0.42
175
1071
573
4452
1.50
11.58
2.6
2.3
78.1
78.4
nmol/l
0.08
528
3953
166
952
1.85
11.32
3.5
2.7
65.4
66.3
g/l
0.77
153
864
146
804
1.92
11.29
2.1
1.6
—
—
—
0
0
55
200
2.83
11.23
1.8
3.6
70.5
62.2
%
1.78
55
200
132
713
1.94
10.80
8.9
9.6
1.3
1.3
%
0.44
132
707
117
606
2.02
10.79
7.9
10.3
24.2
24.5
mmol/l
0.54
110
571
183
1098
1.77
10.74
3.0
2.2
0.2
0.2
g/l
0.20
167
1026
169
1006
1.78
10.17
7.0
7.6
1.3
1.4
mmol/l
0.80
162
968
67
284
2.43
10.10
1.6
1.6
—
—
—
0
0
59
238
2.55
9.88
1.5
1.4
—
—
—
0
0
58
233
2.56
9.79
1.6
1.6
—
—
—
0
0
313
2208
1.55
9.64
1.9
1.8
1124.6
1176.2
nmol/l
0.48
252
1650
136
771
1.85
9.60
5.3
4.3
2.4
1.8
mmol/l
1.09
106
579
54
212
2.61
9.56
13.9
6.2
403.3
315.7
iu/ml
0.21
14
32
196
1239
1.68
9.49
3.3
3.0
9.0
8.3
umol/l
0.17
169
1075
155
921
1.77
9.37
5.5
3.7
1.2
1.2
mmol/l
0.21
146
798
93
470
2.05
9.18
2.2
1.9
—
—
—
0
0
51
199
2.62
9.15
3.4
3.4
61.1
57.5
%
1.09
51
199
333
2406
1.51
9.12
3.3
2.6
5.2
5.8
e6/l
0.38
291
2122
41
145
2.89
8.85
1.5
1.5
—
—
—
0
0
138
807
1.79
8.80
5.5
4.3
5.3
5.2
kpa
0.79
128
754
41
146
2.87
8.75
1.5
1.5
—
—
—
0
0
41
146
2.87
8.75
1.5
1.5
—
—
—
0
0
41
147
2.85
8.64
1.5
1.5
—
—
—
0
0
41
147
2.85
8.64
1.5
1.5
—
—
—
0
0
12
16
7.56
8.42
1.1
3.1
—
—
—
0
0
48
190
2.58
8.39
3.1
3.1
4.2
4.4
e9/l
0.29
48
190
84
425
2.04
8.29
2.2
1.8
—
—
—
0
0
102
553
1.91
8.27
5.3
3.2
25.6
25.2
mmol/l
0.51
95
536
57
248
2.36
8.16
1.3
1.3
—
—
—
0
0
718
6078
1.39
8.02
2.6
2.7
—
—
—
0
0
1150
10621
1.59
7.94
28.6
15.1
25.8
25.2
mg/l
0.24
1052
8479
61
278
2.25
7.85
1.6
1.7
—
—
—
0
0
45
181
2.54
7.63
1.3
1.3
—
—
—
0
0
376
2869
1.43
7.59
3.7
2.8
3795.4
6709.4
umol/l
0.72
330
2453
39
147
2.70
7.52
1.6
1.5
—
—
—
0
0
145
908
1.67
7.24
4.5
3.9
119.0
87.3
ng/l
1.91
127
789
435
3445
1.39
6.99
3.7
3.1
6.9
7.3
mmol/l
1.59
354
2879
32
113
2.88
6.98
1.3
1.3
7.0
6.6
mmol/l
0.41
32
106
102
586
1.80
6.92
5.2
4.7
24.3
24.0
mmol/l
0.38
91
534
32
114
2.85
6.87
1.3
1.2
52.5
53.0
u/l
0.02
19
82
17
40
4.29
6.76
1.1
1.1
96.8
99.6
%
0.11
17
34
40
162
2.51
6.72
1.5
1.5
—
—
—
0
0
66
337
2.01
6.40
1.2
1.3
—
—
—
0
0
19
51
3.76
6.37
1.1
1.1
1.1
1.1
ratio
0.16
13
15
896
8021
1.36
6.21
5.6
4.1
15.3
12.9
mm/h
4.02
827
7367
33
128
2.62
6.07
1.4
1.6
—
—
—
0
0
22
68
3.27
6.01
1.2
1.3
—
—
—
0
0
22
68
3.27
6.01
1.2
1.3
—
—
—
0
0
50
237
2.15
5.92
2.2
2.5
15.9
16.1
%
0.05
22
124
768
6748
1.32
5.88
4.7
3.2
63.1
51.7
u/l
2.09
711
6272
24
80
3.04
5.82
1.2
1.2
7.3
13.6
u/l
1.58
24
72
71
385
1.89
5.81
2.3
3.0
—
—
—
0
0
345
2716
1.36
5.54
1.6
1.6
20.4
20.8
nmol/l
0.15
291
2304
29
114
2.58
5.23
6.2
7.4
6.7
7.2
mmol/l
0.33
23
97
66
363
1.86
5.20
3.6
3.7
47.1
70.9
mg/l
0.69
52
295
66
364
1.86
5.16
3.6
3.7
56.7
46.6
mg/l
0.27
52
297
65
357
1.86
5.15
3.6
3.6
1.5
1.7
ratio
—
6
33
38
171
2.26
5.13
1.6
1.5
126.1
107.6
u/ml
—
7
27
57
302
1.93
5.04
3.0
3.3
25.6
24.9
mmol/l
0.49
47
264
138
935
1.53
4.98
4.2
3.5
5.3
4.6
kpa
0.80
128
901
386
3136
1.32
4.95
3.9
3.2
0.4
0.5
e6/l
0.60
305
2405
14
37
3.81
4.82
2.3
1.9
2.7
6.3
ug/l
—
8
29
154
2148
0.68
4.81
3.2
3.1
0.7
0.8
ug/l
0.36
109
1482
42
206
2.07
4.62
1.6
1.7
—
—
—
0
0
70
411
1.74
4.49
1.8
2.6
3.2
3.1
g/l
0.19
56
321
74
442
1.71
4.47
1.8
2.6
7.7
7.4
g/l
0.79
57
330
74
442
1.71
4.47
1.8
2.6
—
—
—
0
0
74
442
1.71
4.47
1.8
2.6
3.6
3.7
g/l
0.35
56
316
47
245
1.95
4.39
2.3
2.1
124.4
130.1
g/l
0.56
33
181
420
3499
1.29
4.39
4.3
3.9
14.7
8.2
mg/mmol
1.19
269
2194
1169
11103
1.42
4.36
32.2
17.7
139.4
139.7
mmol/l
4.35
1152
10801
48
255
1.92
4.25
1.3
1.3
—
—
—
0
0
48
255
1.92
4.25
1.3
1.3
—
—
—
0
0
68
404
1.72
4.20
5.7
4.0
1.3
1.3
mmol/l
0.32
68
396
31
141
2.23
4.14
1.2
1.1
118.4
116.3
%
0.14
31
130
17
57
3.01
4.13
1.1
1.2
89.5
82.2
u/l
0.19
17
46
17
57
3.01
4.13
1.1
1.2
24.5
23.3
u/l
0.06
17
44
541
4682
1.26
4.08
2.2
2.0
97.1
94.3
pmol/l
0.61
282
2413
31
142
2.21
4.07
1.4
1.2
1.4
3.6
u/ml
0.69
12
42
38
189
2.04
4.06
2.4
3.9
1.7
1.4
%
0.20
28
153
139
986
1.46
4.03
2.1
2.2
356.8
370.0
nmol/l
0.37
128
900
72
440
1.67
4.03
2.2
3.3
100.8
9162.3
u/ml
0.82
58
375
9
14
6.46
3.98
1.0
1.1
—
—
—
0
0
9
14
6.46
3.98
1.0
1.1
—
—
—
0
0
68
411
1.69
3.96
1.9
2.6
9.4
10.5
g/l
0.91
59
349
1168
11130
1.39
3.92
32.5
17.8
4.0
4.0
mmol/l
1.09
1151
10817
38
192
2.01
3.90
1.2
1.5
—
—
—
0
0
16
54
2.99
3.85
1.2
1.3
—
—
—
0
0
16
54
2.99
3.85
1.2
1.3
—
—
—
0
0
20
77
2.62
3.81
1.5
1.6
6.4
7.2
u/l
0.08
11
41
108
740
1.50
3.74
1.8
1.6
—
—
—
0
0
17
61
2.81
3.69
1.9
1.9
—
—
—
0
0
34
169
2.04
3.66
1.1
1.5
—
—
—
0
0
18
67
2.71
3.66
1.5
1.3
—
—
—
0
0
272
2195
1.30
3.54
1.3
1.3
1.7
1.5
u/ml
0.11
57
567
17
63
2.72
3.49
1.5
2.4
—
—
—
0
0
30
146
2.08
3.43
1.1
1.5
—
—
—
0
0
14
47
3.00
3.41
1.2
1.0
—
—
—
0
0
44
246
1.82
3.39
1.5
1.4
—
—
—
0
0
18
70
2.59
3.39
1.4
2.5
21.1
12.8
%
1.36
13
35
47
270
1.77
3.32
2.3
3.1
0.8
0.8
nmol/l
0.11
27
214
17
65
2.64
3.31
1.4
1.2
13.5
18.8
u/l
0.38
12
57
25
115
2.20
3.30
1.4
1.4
42.1
32.6
u/l
0.54
25
91
464
4042
1.23
3.10
4.6
3.9
—
—
—
0
0
11
34
3.25
3.06
1.5
1.1
10.0
31.8
%
2.96
11
28
54
331
1.66
3.05
1.6
1.4
251.7
276.1
ug/g
0.42
29
191
8
16
5.02
3.05
1.8
2.5
—
—
—
0
0
36
196
1.86
3.04
1.4
1.3
—
—
—
0
0
13
45
2.91
3.03
1.6
1.2
74.3
55.5
%
1.27
13
31
27
135
2.02
2.92
1.3
2.2
56.2
2461.8
u/l
0.59
11
43
21
95
2.23
2.90
1.3
1.4
—
—
—
0
0
7
13
5.41
2.87
21.6
11.6
4.5
6.2
mmol/l
—
7
13
281
2338
1.26
2.83
3.9
4.0
1.0
1.0
kg/l
1.03
44
365
34
188
1.83
2.76
1.5
1.3
272.0
301.4
u/ml
0.20
23
100
148
1146
1.33
2.60
2.1
2.2
111.7
122.1
ug/g
0.27
120
910
58
378
1.56
2.60
2.0
2.8
1.4
1.2
g/l
0.06
52
327
28
149
1.90
2.57
2.0
2.0
31.3
32.5
pg
0.65
28
149
58
382
1.54
2.49
1.5
1.4
32.6
33.5
iu/l
0.08
48
321
7
16
4.39
2.47
1.9
2.5
—
—
—
0
0
330
2838
1.22
2.42
4.7
3.9
0.0
0.0
estimate
0.88
123
934
16
70
2.30
2.41
1.8
1.8
—
—
—
0
0
132
1018
1.33
2.40
3.0
2.4
36.4
40.9
u/l
0.28
112
856
15
64
2.36
2.39
1.6
1.9
—
—
—
0
0
15
64
2.36
2.39
1.6
1.9
—
—
—
0
0
15
64
2.36
2.39
1.6
1.9
—
—
—
0
0
15
64
2.36
2.39
1.6
1.9
—
—
—
0
0
27
146
1.87
2.38
1.1
1.1
—
—
—
0
0
26
140
1.87
2.33
1.3
1.2
0.5
0.6
nmol/l
0.96
26
131
927
8753
1.19
2.31
33.4
18.5
14.0
13.8
%
5.96
914
8554
35
208
1.70
2.28
1.2
1.4
19.0
11.3
u/l
1.44
26
158
21
106
2.00
2.26
1.1
1.2
—
—
—
0
0
26
142
1.85
2.24
1.3
1.2
—
0.4
nmol/l
—
0
10
13
283
0.45
2.21
1.7
1.5
—
—
—
0
0
8
24
3.35
2.18
1.1
1.0
—
—
—
0
0
580
5294
1.17
2.11
4.5
3.7
0.0
0.0
estimate
0.80
124
947
21
109
1.94
2.11
1.2
1.7
—
—
—
0
0
6
15
4.01
2.04
7.2
5.8
—
—
—
0
0
22
118
1.88
2.02
1.8
1.8
—
—
—
0
0
18
91
1.99
1.95
1.4
1.6
—
—
—
0
0
26
149
1.76
1.95
3.0
2.2
4.3
32.0
u/ml
0.54
26
143
8
27
2.97
1.93
1.4
1.3
30.3
24.6
%
—
8
18
6
16
3.76
1.93
1.2
1.1
—
—
—
0
0
6
16
3.76
1.93
1.3
1.1
—
—
—
0
0
6
16
3.76
1.93
1.3
1.1
100.0
89.7
%
—
6
16
6
16
3.76
1.93
5.3
1.4
94.7
100.7
%
—
6
16
572
5243
1.16
1.92
5.8
5.1
0.0
0.0
estimate
0.50
129
967
26
150
1.75
1.91
2.2
2.4
19.9
26.4
mg/l
—
7
39
20
106
1.90
1.91
1.6
1.6
—
—
—
0
0
20
106
1.90
1.91
1.6
1.6
—
—
—
0
0
20
106
1.90
1.91
1.6
1.6
—
—
—
0
0
23
128
1.81
1.90
1.9
1.8
—
—
—
0
0
861
8140
1.16
1.89
4.2
4.0
14.9
14.9
pmol/l
0.01
778
7354
281
2435
1.20
1.89
1.9
1.7
49327820.3
11028006.0
pmol/l
0.36
223
1995
23
129
1.80
1.86
1.3
1.3
—
—
—
0
0
18
93
1.95
1.85
3.7
2.1
—
—
—
0
0
570
5236
1.15
1.84
4.4
3.7
0.0
0.0
estimate
0.00
127
965
82
620
1.34
1.76
1.3
1.3
148.5
193.6
u/ml
0.55
77
568
25
147
1.71
1.74
1.4
1.2
2.7
6.8
u/ml
1.07
14
61
42
282
1.51
1.73
2.5
2.5
236.0
81.9
ug/min
0.56
21
165
5
13
3.86
1.71
1.2
1.0
—
—
—
0
0
28
172
1.64
1.68
1.2
1.1
—
—
—
0
0
25
149
1.69
1.67
1.0
1.5
—
—
—
0
0
13
62
2.11
1.65
3.5
2.5
—
—
—
0
0
85
653
1.32
1.65
1.6
1.5
—
—
—
0
0
61
445
1.39
1.65
1.7
2.0
34.2
39.8
u/l
1.47
55
397
18
98
1.85
1.62
2.6
1.4
9088.3
190860.6
e6/l
1.10
12
68
8
32
2.51
1.60
7.9
4.4
66.8
68.8
%
—
8
26
11
50
2.21
1.57
1.7
2.7
1110.8
1600.8
u/ml
0.33
11
50
12
57
2.12
1.55
1.1
1.5
—
—
—
0
0
12
57
2.12
1.55
1.1
1.5
—
—
—
0
0
1012
9743
1.16
1.54
5.3
4.8
2.0
2.1
mu/l
0.22
925
8849
89
696
1.30
1.54
2.0
2.2
12.2
12.3
nmol/l
0.04
78
604
5
15
3.34
1.52
1.0
1.1
—
—
—
0
0
7
28
2.51
1.45
1.1
1.6
—
—
—
0
0
59
774
0.75
1.36
1.7
1.8
—
—
—
0
0
162
1379
1.20
1.35
5.0
4.6
33.4
32.6
%
0.40
107
926
20
120
1.68
1.34
2.0
3.7
61.3
54.3
%
0.79
13
85
0
38
0.00
1.34
0.0
1.9
—
—
—
0
0
77
605
1.29
1.32
3.0
3.3
4.3
4.5
pmol/l
0.88
68
524
1158
11303
1.18
1.31
17.2
10.8
28.4
25.7
u/l
0.87
1126
10882
37
259
1.44
1.30
1.4
1.3
—
—
—
0
0
5
18
2.78
1.28
1.0
1.4
—
—
—
0
0
13
70
1.87
1.24
1.1
1.5
—
—
—
0
0
22
139
1.59
1.23
1.9
1.7
54.3
63.5
%
0.46
17
85
37
263
1.42
1.21
1.2
1.1
—
—
—
0
0
205
1804
1.16
1.17
3.5
3.0
2.6
2.3
e6/l
0.17
120
1021
985
9531
1.13
1.16
29.3
16.6
37.2
39.3
%
7.87
637
6530
14
80
1.76
1.13
2.4
2.2
380.8
651.7
e6/l
—
5
31
7
30
2.34
1.12
1.4
1.3
10.6
8.5
ug/l
—
7
30
7
31
2.26
1.10
1.1
1.1
—
—
—
0
0
18
112
1.62
1.09
1.1
1.1
—
—
—
0
0
19
120
1.59
1.09
2.2
2.7
—
—
—
0
0
170
1484
1.17
1.08
1.3
1.5
—
—
—
0
0
7
32
2.19
1.08
1.1
1.1
—
—
—
0
0
65
517
1.27
1.05
5.3
3.7
51.0
48.6
%
0.33
65
510
1033
10046
1.12
1.04
4.8
4.1
1.3
1.3
mmol/l
1.85
941
9098
5
22
2.28
1.03
2.2
3.5
13.9
14.4
ml/dl
—
5
17
17
106
1.61
1.03
1.2
1.1
87.1
95.6
%
0.70
17
100
322
2948
1.12
1.02
1.8
1.7
1.4
1.4
mmol/l
0.54
270
2470
32
230
1.40
1.02
1.5
1.5
111.2
287.7
pmol/l
1.34
32
225
39
291
1.35
1.00
1.5
1.6
—
—
—
0
0
5
23
2.18
0.98
1.2
1.4
—
—
—
0
0
9
51
1.77
0.94
1.1
1.9
—
—
—
0
0
6
29
2.07
0.89
1.0
1.3
—
—
—
0
0
10
56
1.79
0.88
1.1
1.1
—
—
—
0
0
40
309
1.30
0.84
2.0
1.4
—
—
—
0
0
18
121
1.49
0.83
1.1
1.1
—
—
—
0
0
6
32
1.88
0.82
1.0
1.2
0.3
0.3
g/l
—
6
26
156
1388
1.14
0.81
10.3
7.3
—
—
—
0
0
9
148
0.61
0.79
1.0
1.0
—
—
—
0
0
14
90
1.56
0.78
1.3
1.1
—
176.4
—
0
14
6
34
1.77
0.76
1.2
1.1
—
—
—
0
0
5
24
2.09
0.74
1.2
1.1
—
—
—
0
0
210
1916
1.11
0.73
3.5
2.8
1.2
1.3
e6/l
0.08
125
1125
10
60
1.67
0.72
1.4
1.1
—
—
—
0
0
10
60
1.67
0.72
6.1
3.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
60
1.67
0.72
1.0
1.2
—
—
—
0
0
1021
9988
1.09
0.72
7.3
6.0
41.0
40.2
mmol/mol
1.72
940
9199
5
27
1.85
0.68
2.0
1.5
—
—
—
0
0
34
267
1.28
0.67
2.4
1.7
10252.3
15650.6
e6/l
0.58
26
197
123
1096
1.13
0.65
2.0
1.8
1.5
1.5
%
0.05
105
943
29
224
1.30
0.65
1.3
1.3
275.1
240.5
miu/ml
—
10
105
13
87
1.50
0.63
1.3
1.1
—
—
—
0
0
8
49
1.64
0.62
1.0
1.3
—
—
—
0
0
20
147
1.37
0.62
1.2
1.1
—
—
—
0
0
30
235
1.28
0.61
4.3
1.6
0.8
0.8
nmol/l
0.22
23
194
14
96
1.46
0.61
1.9
2.2
0.2
2.7
u/field
—
5
38
8
50
1.60
0.61
6.0
4.4
—
—
—
0
0
13
88
1.48
0.60
1.5
1.2
1.3
0.8
u/ml
—
7
40
8
51
1.57
0.60
2.0
2.0
—
—
—
0
0
8
51
1.57
0.60
2.0
2.0
—
—
—
0
0
20
148
1.36
0.60
1.9
1.4
—
—
—
0
0
8
52
1.54
0.59
2.0
2.0
—
—
—
0
0
6
35
1.72
0.57
2.5
3.0
—
—
—
0
0
6
35
1.72
0.57
2.5
3.0
—
—
—
0
0
6
35
1.72
0.57
1.2
1.1
—
—
—
0
0
6
36
1.67
0.56
1.2
1.0
1269.7
1626.0
miu/ml
—
6
36
15
205
0.73
0.54
1.0
1.7
—
—
—
0
0
11
74
1.49
0.53
1.3
1.3
—
—
—
0
0
1056
10391
1.08
0.52
5.3
4.5
1.4
1.5
mmol/l
4.70
969
9473
6
40
1.50
0.51
1.0
1.2
135.8
178.8
iu/ml
—
6
40
6
40
1.50
0.51
1.5
2.0
19.7
223.2
ug/l
—
6
34
20
153
1.31
0.50
1.2
1.1
—
—
—
0
0
38
316
1.21
0.50
2.0
1.7
—
—
—
0
0
1063
10469
1.08
0.49
5.4
4.6
4.4
4.6
mmol/l
5.85
990
9623
1016
10006
1.06
0.43
24.8
14.0
77.3
77.5
ml/min/173m2
0.11
890
8308
35
294
1.20
0.43
1.3
1.3
—
—
—
0
0
5
31
1.62
0.43
3.8
2.3
—
—
—
0
0
5
31
1.62
0.43
1.2
1.5
—
—
—
0
0
21
261
0.80
0.41
1.8
1.8
4.8
5.4
iu/l
—
6
86
0
17
0.00
0.40
0.0
1.0
—
32.9
—
0
17
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
8
60
1.34
0.40
1.4
1.6
—
—
—
0
0
8
60
1.34
0.40
1.4
1.6
—
—
—
0
0
14
106
1.32
0.39
1.1
1.6
—
—
—
0
0
12
90
1.34
0.36
1.2
1.8
—
—
—
0
0
6
42
1.43
0.35
2.8
1.3
—
—
—
0
0
227
2158
1.06
0.35
2.6
3.1
2.5
2.5
mmol/l
0.12
201
1902
1183
11735
1.07
0.32
41.4
22.3
237.4
248.2
e9/l
6.83
1164
11409
16
128
1.25
0.32
5.6
3.4
—
—
—
0
0
1183
11739
1.07
0.31
41.3
22.2
4.3
4.5
e12/l
25.65
1164
11374
1183
11742
1.07
0.29
41.6
22.4
128.3
134.3
g/l
34.85
1171
11537
13
163
0.80
0.29
1.2
1.2
0.2
2.6
u/ml
—
5
76
147
1388
1.07
0.29
1.4
1.4
—
—
—
0
0
8
67
1.20
0.26
1.1
1.5
—
—
—
0
0
8
67
1.20
0.26
1.1
1.4
—
—
—
0
0
8
67
1.20
0.26
1.1
1.5
—
—
—
0
0
1182
11741
1.06
0.25
41.4
22.3
6.8
6.7
e9/l
0.12
1163
11377
9
73
1.23
0.25
1.9
1.2
—
—
—
0
0
9
73
1.23
0.25
1.9
1.2
—
—
—
0
0
12
96
1.25
0.24
2.0
2.4
745.5
624.9
ml
—
6
60
1050
10405
1.04
0.24
5.5
4.7
6.1
6.0
mmol/l
1.20
946
9418
11
87
1.27
0.24
1.0
1.3
—
—
—
0
0
9
77
1.17
0.24
1.1
1.1
—
—
—
0
0
186
1782
1.05
0.24
1.3
1.3
27.0
35.6
iu/ml
0.71
59
575
14
115
1.22
0.23
1.4
1.6
—
—
—
0
0
10
79
1.27
0.22
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
4.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
1.6
—
0
7
0
14
0.00
0.20
0.0
1.0
—
24.2
—
0
8
64
598
1.07
0.19
1.5
1.8
—
—
—
0
0
7
59
1.19
0.18
2.3
1.3
—
—
—
0
0
7
59
1.19
0.18
1.1
1.2
—
—
—
0
0
11
91
1.21
0.17
1.1
1.0
—
—
—
0
0
29
262
1.11
0.17
4.5
3.0
1.6
1.5
mmol/l
0.13
29
257
8
69
1.16
0.16
1.0
1.6
—
—
—
0
0
175
1695
1.04
0.16
1.3
1.3
6.1
11.5
u/ml
0.75
52
631
9
79
1.14
0.15
1.1
1.1
—
—
—
0
0
9
79
1.14
0.15
1.1
1.1
—
—
—
0
0
92
880
1.05
0.14
3.7
2.9
57.0
63.9
ml/min/173m2
1.07
43
373
45
480
0.94
0.14
1.6
1.3
—
—
—
0
0
10
84
1.19
0.14
1.0
1.1
—
—
—
0
0
33
305
1.08
0.13
1.9
1.6
—
—
—
0
0
34
315
1.08
0.13
1.6
1.6
0.2
20.8
iu/ml
0.49
13
58
26
238
1.09
0.13
5.7
3.6
27.3
27.7
mg/l
0.02
16
153
27
248
1.09
0.12
4.8
3.1
7.5
7.5
mmol/l
0.00
27
243
376
3701
1.02
0.12
4.9
5.2
4.2
2.8
ug/l
0.52
338
3288
24
262
0.91
0.12
1.1
1.7
—
—
—
0
0
5
46
1.09
0.09
1.4
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
1074
10698
1.02
0.09
6.0
5.1
2.5
2.7
mmol/l
8.20
986
9775
6
73
0.82
0.07
2.0
1.4
—
—
—
0
0
8
77
1.04
0.07
1.1
1.1
—
—
—
0
0
8
94
0.85
0.06
1.1
1.3
—
—
—
0
0
11
100
1.10
0.05
1.1
1.0
—
—
—
0
0
31
322
0.96
0.04
2.3
1.8
—
—
—
0
0
65
638
1.02
0.03
1.1
1.2
87.8
148.0
iu/ml
0.75
14
250
33
321
1.03
0.02
1.2
1.2
—
—
—
0
0
33
322
1.03
0.01
1.2
1.2
—
—
—
0
0
21
204
1.03
0.00
1.3
1.2
1.2
3.0
u/ml
—
5
15
25
244
1.03
0.00
1.4
1.7
2652.0
957.3
e6/l
0.28
19
195
25
244
1.03
0.00
1.3
1.7
29.5
45.3
e6/l
0.19
19
190
26
262
0.99
0.00
1.4
1.2
7.8
13.0
u/ml
—
9
41
48
478
1.00
0.00
1.0
1.0
—
—
—
0
0
53
532
1.00
0.00
1.5
1.7
—
—
—
0
0
296
2964
1.00
0.00
4.7
4.4
22.6
21.4
%
0.61
142
1493
17
167
1.02
0.00
1.0
1.1
—
14.8
—
0
8
26
257
1.01
0.00
1.4
1.2
2.4
3.4
u/ml
—
9
25
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.0
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
362.6
—
0
5
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
8
79
1.01
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
0.00
1.8
2.0
60.0
49.8
umol/l
—
5
37
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
7.4
—
0
6
5
59
0.85
0.00
1.2
1.2
217.6
471.5
u/l
—
5
51
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
38.6
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
20.6
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint I9_OTHOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_OTHOTH | 2.025 [1.78, 2.3] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.108 |
During the follow-up period (1.1.1998 — 31.12.2019), 884 out of 2678 females with I9_OTHOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_OTHOTH | 1.619 [1.46, 1.8] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 1135 out of 2662 males with I9_OTHOTH died.
Mortality risk
Mortality risk for people of age
years, who have I9_OTHOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.181% | 0.287% |
| 5 | 1.177% | 1.963% |
| 10 | 2.826% | 5.128% |
| 15 | 5.609% | 9.404% |
| 20 | 9.422% | 15.918% |
Relationships between endpoints
↥Index endpoint: I9_OTHOTH – Other other unspecified disorders of the circulatory system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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