phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.
Other acute skin changes due to ultraviolet radiation
DOID EFO Endpoint Browser PheWeb
L12_OTHACUSKINSUN
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
685 |
4. Check minimum number of eventsNone |
685 |
5. Include endpoints |
1353 |
6. Filter based on genotype QC (FinnGen only) |
1316 |
Control definitions (FinnGen only)
- Control exclude
- L12_RADIATIONRELATEDSKIN
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L55-L59
- Name in latin
- Aliae commutationes acutae cutis e radiatione ultraviolacea
Similar endpoints
↥List of similar endpoints to
Other acute skin changes due to ultraviolet radiation
based on the number of shared cases.
Similar with more cases:
- Radiation-related disorders of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12305 | 6288 | 5855 |
| Only index persons | 8709 | 4853 | 3856 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.17 | 0.18 | 0.16 |
| Only index persons | 0.16 | 0.18 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 44.15 | 46.17 | 41.73 |
| Only index persons | 37.54 | 41.00 | 33.18 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1316 | 712 | 604 |
| Unadjusted period prevalence (%) | 0.26 | 0.25 | 0.28 |
| Median age at first event (years) | 41.44 | 41.86 | 40.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1353
- Matched controls
- 13530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L56.4
ICD-10 Finland
Polymorphous light eruption
268.9
307.7
278
13
69282
ICD-8 Finland
Other eczema and dermatitis, E microbis
+∞
307.7
484
*
L56.8
ICD-10 Finland
Other specified acute skin changes due to ultraviolet radiation
+∞
244.4
227
*
L57.0
ICD-10 Finland
Actinic keratosis
9.7
165.3
209
251
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.9
165.0
292
516
D07AB08
ATC
desonide; topical
5.1
124.4
315
764
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
17.9
104.7
86
51
TQW99
NOMESCO Finland
Other minor procedure on skin
7.5
99.2
150
220
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
22.3
97.0
72
34
69288
ICD-8 Finland
Other eczema and dermatitis, E causis alii definitis
+∞
92.8
88
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.5
89.7
408
1483
L56.9
ICD-10 Finland
Acute skin change due to ultraviolet radiation, unspecified
192.6
87.4
90
5
ZXC20
NOMESCO Finland
Use of chemical agents
12.2
83.3
85
74
E0000UV, ,
ATC
3.0
83.1
715
3722
D07AC01
ATC
betamethasone; topical
2.9
76.9
648
3298
E000001, ,
ATC
3.2
75.5
401
1582
D07AB02
ATC
hydrocortisone butyrate; topical
2.9
74.3
545
2568
XQ802
NOMESCO Finland
Epicutan test
6.2
69.3
125
219
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
4.0
67.3
214
603
D07AC13
ATC
mometasone; topical
2.7
64.0
524
2573
69283
ICD-8 Finland
Other eczema and dermatitis, Dysidroticum (pompholyx)
+∞
58.8
56
*
L56.3
ICD-10 Finland
Solar urticaria
209.1
58.5
60
*
D07AA02
ATC
hydrocortisone; topical
3.1
55.6
271
1000
L56.2
ICD-10 Finland
Photocontact dermatitis [berloque dermatitis]
116.8
52.2
56
5
R06AE07
ATC
cetirizine; oral
2.3
49.4
668
4008
E000002, ,
ATC
3.2
47.6
211
732
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.4
47.5
195
645
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
12.4
47.2
47
39
L20.0
ICD-10 Finland
Besnier prurigo
4.1
46.6
138
366
H02AB06
ATC
prednisolone; systemic
2.2
45.6
748
4807
ZXC50
NOMESCO Finland
Cryotherapy
10.5
39.7
44
43
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
12.5
39.4
39
32
D07AD01
ATC
clobetasol; topical
2.5
37.5
281
1277
P01BA02
ATC
hydroxychloroquine; oral
3.2
37.2
165
569
L57.8
ICD-10 Finland
Other skin changes due to chronic exposure to nonionizing radiation
133.8
36.9
39
*
69280
ICD-8 Finland
Other eczema and dermatitis, E radiatione solari
+∞
36.6
35
*
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
8.4
36.5
48
59
EAA10
NOMESCO Finland
Excision of lesion of lip
8.8
36.3
46
54
L30.3
ICD-10 Finland
Infective dermatitis
4.6
35.2
86
196
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.6
34.7
227
964
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
9.6
34.6
41
44
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
9.8
34.3
40
42
D07BC01
ATC
betamethasone and antiseptics; topical
2.6
33.5
218
923
N05BB01
ATC
hydroxyzine; systemic
3.3
33.3
133
430
TQW80
NOMESCO Finland
Local dermatologic skincare
6.1
33.3
59
101
L56.0
ICD-10 Finland
Drug phototoxic response
324.4
32.0
32
*
ZXC10
NOMESCO Finland
Use of laser
5.6
31.9
62
116
XQ800
NOMESCO Finland
Prick test
3.1
30.7
135
462
D11AH01
ATC
tacrolimus; topical
10.9
28.7
31
29
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.6
26.2
88
254
E000003, ,
ATC
3.6
26.1
89
259
R06AX27
ATC
desloratadine; oral
2.0
25.9
382
2245
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
4.0
25.8
76
200
D02AX
ATC
Other emollients and protectives
4.4
25.0
63
147
XQ848
NOMESCO Finland
Dermatological photography
4.9
24.2
54
114
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
31.7
23.8
31
10
D07XC01
ATC
betamethasone; topical
2.3
23.2
195
920
E000007, ,
ATC
3.2
22.5
94
311
69200
ICD-8 Finland
Other eczema and dermatitis, Due to detergents
116.9
21.6
23
*
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
6.5
20.2
33
52
69240
ICD-8 Finland
Other eczema and dermatitis, Due to other chemicals
27.5
20.1
27
10
E000006, ,
ATC
2.7
19.8
114
450
D07CC01
ATC
betamethasone and antibiotics; topical
2.2
19.6
195
982
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
7.0
19.6
30
44
H02AB07
ATC
prednisone; oral
2.1
19.0
215
1136
D05BB02
ATC
acitretin; oral
4.4
18.8
47
109
R06AE09
ATC
levocetirizine; oral
2.1
18.6
197
1016
D04.0
ICD-10 Finland
Carcinoma in situ: Skin of lip
192.6
18.6
19
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.3
18.4
71
224
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.1
18.4
39
79
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
18.2
316
1927
D07XB05
ATC
dexamethasone; topical
3.7
16.9
53
146
D09AB01
ATC
zinc bandage without supplements; topical
4.7
16.9
39
85
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
16.8
266
1572
6927F
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[ERUPTIO POLYMORPHICA SOLARIS]
+∞
16.7
16
*
XQ806
NOMESCO Finland
Minimal Erythema Dose (MED) test
172.0
16.5
17
*
L93.0
ICD-10 Finland
Discoid lupus erythematosus
14.5
16.3
27
19
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.3
16.2
62
195
J01FF01
ATC
clindamycin; systemic
1.7
15.9
369
2436
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
26.6
15.6
21
8
R06AX22
ATC
ebastine; oral
1.9
15.6
233
1351
L04AX03
ATC
methotrexate; systemic
2.2
15.2
141
689
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
45.5
15.1
18
*
D06BX01
ATC
metronidazole; topical
2.1
14.6
152
776
L04AX01
ATC
azathioprine; systemic
3.0
14.3
63
215
ZQZ00
NOMESCO Finland
Treatment of several skin areas
27.5
14.3
19
7
EAA30
NOMESCO Finland
Partial excision of lower lip
27.5
14.3
19
7
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
14.2
275
1720
S29
ICPC
Skin symptom/complaint other
1.8
14.1
240
1445
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
17.8
13.8
21
12
L71.8
ICD-10 Finland
Other rosacea
4.7
13.8
32
70
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
6.6
13.7
22
34
S01GX01
ATC
cromoglicic acid; ophthalmic
1.8
13.6
247
1514
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.2
13.6
113
528
L30.0
ICD-10 Finland
Nummular dermatitis
3.0
13.5
61
212
R03DC03
ATC
montelukast; oral
1.8
13.5
213
1253
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
13.5
392
2725
T78.4
ICD-10 Finland
Allergy, unspecified
2.9
13.4
65
235
N02AX02
ATC
tramadol; systemic, rectal
1.5
13.2
571
4344
D02AE01
ATC
carbamide; topical
2.4
13.0
92
401
J01DB01
ATC
cefalexin; oral
1.7
12.9
1053
9200
68600
ICD-8 Finland
Other local infections of skin and subcutaneous tissue, Pyoderma
50.5
12.9
15
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.6
443
3211
L56.1
ICD-10 Finland
Drug photoallergic response
131.2
12.5
13
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.1
12.4
119
588
Z3231
NOMESCO Finland
Registered nurse
1.6
12.4
359
2485
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.5
12.3
78
323
R06AX13
ATC
loratadine; oral
1.8
12.1
188
1099
L50.8
ICD-10 Finland
Other urticaria
4.0
12.0
34
87
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
21.5
12.0
17
8
R03AC02
ATC
salbutamol; inhalant
1.5
11.8
692
5571
L50.3
ICD-10 Finland
Dermatographic urticaria
3.9
11.4
33
86
D07AC14
ATC
methylprednisolone aceponate; topical
2.5
11.4
74
310
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
11.9
11.3
20
17
A46
ICD-10 Finland
Erysipelas
1.8
11.1
196
1188
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
8.1
11.1
24
30
M25.5
ICD-10 Finland
Pain in joint
1.5
11.0
388
2797
Z71.8
ICD-10 Finland
Other specified counselling
1.6
11.0
362
2570
J01AA04
ATC
lymecycline; systemic
1.8
10.8
161
928
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
4.8
10.7
24
51
S18
ICPC
Laceration/cut
1.5
10.7
553
4311
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.3
10.6
79
352
S76
ICPC
Skin infection other
2.4
10.6
75
327
J01DA01
ATC
[U] cefalexin
1.5
10.6
799
6699
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
10.6
146
821
D05AX02
ATC
calcipotriol; topical
2.7
10.5
56
213
D05AX52
ATC
calcipotriol, combinations; topical
2.4
10.5
71
304
M54.5
ICD-10 Finland
Low back pain
1.5
10.4
436
3256
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
12.1
10.4
18
15
S21
ICPC
Skin texture symptom/complaint
1.8
10.3
169
1001
L57.9
ICD-10 Finland
Skin changes due to chronic exposure to nonionizing radiation, unspecified
32.8
10.3
13
*
ZXC15
NOMESCO Finland
Use of photodynamic technique
10.7
10.3
19
18
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
5.0
10.3
22
45
R06.0
ICD-10 Finland
Dyspnoea
1.5
10.3
352
2516
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
7.5
10.2
23
31
D07AB01
ATC
clobetasone; topical
2.7
10.2
54
205
C03CA01
ATC
furosemide; systemic
1.5
10.1
418
3106
L71.9
ICD-10 Finland
Rosacea, unspecified
3.3
10.0
38
119
M79.6
ICD-10 Finland
Pain in limb
1.5
10.0
508
3931
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
10.0
335
2382
69230
ICD-8 Finland
Other eczema and dermatitis, Due to drugs
40.4
10.0
12
*
R03AC03
ATC
terbutaline; inhalant
1.7
9.9
176
1067
R03BB04
ATC
tiotropium bromide; inhalant
1.8
9.9
155
907
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
9.9
252
1682
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.7
9.9
216
1387
D04.2
ICD-10 Finland
Carcinoma in situ: Skin of ear and external auricular canal
26.2
9.8
13
5
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
26.2
9.8
13
5
11006
ICD-8 Finland
Dermatophytosis, Pedis
26.2
9.8
13
5
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.2
9.7
86
412
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
2.9
9.7
45
159
Z01.2
ICD-10 Finland
Dental examination
1.5
9.7
512
3987
J01AA07
ATC
tetracycline; systemic
1.7
9.7
180
1106
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
9.6
143
824
N06AX11
ATC
mirtazapine; oral
1.5
9.5
421
3167
XQ815
NOMESCO Finland
Photoprovocation test
+∞
9.4
9
*
L26
ICD-10 Finland
Exfoliative dermatitis
21.9
9.4
13
6
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
4.5
9.3
22
49
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
9.3
426
3222
R03BA01
ATC
beclometasone; inhalant
1.7
9.2
182
1138
A01AC01
ATC
triamcinolone; local oral
3.9
9.2
26
67
R03BA05
ATC
fluticasone; inhalant
1.6
9.1
223
1471
A02BC03
ATC
lansoprazole; oral
1.5
9.0
373
2762
J01MA12
ATC
levofloxacin; systemic
1.6
8.9
241
1628
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.8
417
3170
R03AK08
ATC
formoterol and beclometasone; inhalant
2.3
8.7
62
272
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.5
8.7
29
84
ZZR00
NOMESCO Finland
Flap of skin
3.2
8.7
33
104
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
8.5
544
4359
D20
ICPC
Mouth/tongue/lip symptom/complaint
2.4
8.5
59
256
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
20.2
8.5
12
6
N05CF01
ATC
zopiclone; oral
1.4
8.5
416
3179
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
8.5
567
4581
J01DA09
ATC
[U] cefadroxil
1.5
8.4
326
2378
R96
ICPC
Asthma
1.8
8.4
119
674
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.4
8.4
55
232
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
8.4
118
667
L50.9
ICD-10 Finland
Urticaria, unspecified
2.6
8.4
47
184
A01AB09
ATC
miconazole; local oral
1.9
8.4
112
623
J01AA02
ATC
doxycycline; systemic
1.5
8.4
992
8842
R42
ICD-10 Finland
Dizziness and giddiness
1.5
8.4
280
1982
D11AX14
ATC
[U] tacrolimus
9.5
8.3
16
17
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
8.3
186
1200
J01FA06
ATC
roxithromycin; oral
1.4
8.3
493
3899
L43.9
ICD-10 Finland
Lichen planus, unspecified
3.3
8.2
30
92
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
8.2
321
2344
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
14.6
8.2
13
9
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.7
8.2
161
1003
J01FA01
ATC
erythromycin; systemic
1.7
8.2
154
949
C07AB07
ATC
bisoprolol; oral
1.4
8.1
622
5129
L17
ICPC
Foot/toe symptom/complaint
1.5
8.1
337
2491
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
8.2
8.1
17
21
L20
ICD-10 Finland
Atopic dermatitis
3.0
8.1
34
114
N03AX12
ATC
[U] gabapentin; oral
1.6
8.0
207
1381
J02AC01
ATC
fluconazole; systemic
1.4
8.0
449
3510
S87
ICPC
Dermatitis/atopic eczema
3.0
7.9
33
110
N03AX16
ATC
[U] pregabalin
1.5
7.8
288
2077
J01MA14
ATC
moxifloxacin; systemic
1.8
7.8
117
676
J45
ICD-10 Finland
Asthma
1.8
7.7
121
707
R03BA02
ATC
budesonide; inhalant
1.6
7.7
216
1468
L16
ICPC
Ankle symptom/complaint
1.7
7.6
133
803
70908
ICD-8 Finland
Other diseases of skin, Alii definiti
25.2
7.6
10
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.5
268
1918
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
7.5
92
498
L08
ICPC
Shoulder symptom/complaint
1.5
7.5
251
1774
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
4.4
7.4
18
41
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
7.4
63
298
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
7.4
164
1055
M79.7
ICD-10 Finland
Fibromyalgia
2.4
7.3
47
197
6929A
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA NUMMULARE]
+∞
7.3
7
*
6927X
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[DERMATITIS PHOTOTOXICA NUD]
+∞
7.3
7
*
D06BB10
ATC
imiquimod; topical
2.4
7.3
50
216
R53
ICD-10 Finland
Malaise and fatigue
1.5
7.3
287
2094
L43.8
ICD-10 Finland
Other lichen planus
3.3
7.3
26
79
R01AD08
ATC
fluticasone; nasal
1.4
7.2
325
2432
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
7.2
512
4147
D11AX15
ATC
[U] pimecrolimus
30.2
7.2
9
*
69009
ICD-8 Finland
Seborrhoeic dermatitis, Unspecified
20.1
7.1
10
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.1
157
1007
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
6.6
7.1
17
26
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
7.1
205
1402
D02BB01
ATC
betacarotene; oral
12.1
7.1
12
10
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
7.0
144
907
C08CA05
ATC
nifedipine; systemic
1.9
7.0
83
444
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.9
7.0
20
52
Z2221
NOMESCO Finland
Medical doctor
1.4
7.0
327
2464
R01AD09
ATC
mometasone; nasal
1.4
6.9
516
4203
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
6.9
180
1203
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.5
6.9
40
160
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
6.8
264
1919
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.9
6.8
80
428
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
6.8
130
805
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
2.9
6.8
30
104
UJF32
NOMESCO Finland
Coloscopy
1.4
6.8
318
2396
L01BC02
ATC
fluorouracil; systemic, topical
40.3
6.8
8
*
G47.3
ICD-10 Finland
Sleep apnoea
1.5
6.8
259
1878
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
6.7
190
1293
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
6.7
201
1386
E000004, ,
ATC
3.1
6.6
27
89
Z71
ICD-10 Finland
Persons encountering health services for other counselling and medical advice, not elsewhere classified
2.4
6.6
44
188
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.6
755
6551
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
6.6
829
7296
C09CA01
ATC
losartan; oral
1.4
6.6
307
2309
H02AB04
ATC
methylprednisolone; systemic
1.6
6.5
172
1151
R04.0
ICD-10 Finland
Epistaxis
1.8
6.5
94
536
M79.1
ICD-10 Finland
Myalgia
1.6
6.5
163
1079
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
2.1
6.5
61
301
WYA10
NOMESCO Finland
Emergency care or similar visit
1.9
6.5
85
471
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
5.4
6.5
18
34
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
6.5
829
7306
D06AX01
ATC
fusidic acid; topical
1.7
6.4
112
675
L04AB04
ATC
adalimumab; parenteral
3.0
6.4
28
96
69830
ICD-8 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus
70.2
6.4
7
*
6924B
ICD-9 Finland
Contact dermatitis and other eczema, Due to other chemical products[DERMATITIS ARTEFACTA E METALLIS ALLERGICA]
70.2
6.4
7
*
A02BC05
ATC
esomeprazole; systemic
1.4
6.4
483
3930
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
6.4
104
616
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.3
6.3
45
198
L50.0
ICD-10 Finland
Allergic urticaria
2.6
6.3
34
131
L29.8
ICD-10 Finland
Other pruritus
3.6
6.3
20
56
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
9.3
6.3
12
13
S88
ICPC
Dermatitis contact/allergic
3.0
6.3
27
92
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
6.3
159
1055
R83
ICPC
Respiratory infection other
1.5
6.3
253
1851
K13.09
ICD-10 Finland
Disease of the lips UNS
18.1
6.3
9
5
L56
ICD-10 Finland
Other acute skin changes due to ultraviolet radiation
+∞
6.3
6
*
6927A
ICD-9 Finland
Contact dermatitis and other eczema, Due to solar radiation[ERYTHEMA SOLARE]
+∞
6.3
6
*
Y1203, ,
ICD-8 Finland
+∞
6.3
6
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.2
465
3776
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.8
6.2
83
463
M01AE02
ATC
naproxen; oral, rectal
1.3
6.2
662
5666
F29
ICPC
Eye symptom/complaint other
1.7
6.2
108
653
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
6.1
319
2444
Z3226
NOMESCO Finland
Physiotherapist
1.5
6.1
218
1558
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
6.1
221
1584
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.3
6.0
44
196
H01
ICPC
Ear pain/earache
1.7
6.0
119
743
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
103
379
2.86
20.48
1.3
1.2
0.74
1.00
u/ml
—
7
33
83
284
3.05
18.78
1.3
1.2
21.51
32.50
u/ml
—
9
13
84
297
2.95
17.95
2.2
1.5
0.22
0.24
g/l
1.37
79
286
66
212
3.22
16.62
1.3
1.2
5.63
6.84
u/ml
—
10
16
76
269
2.93
16.21
1.4
1.2
1.80
2.81
u/ml
1.25
18
30
76
272
2.90
15.90
1.4
1.2
2.27
8.39
u/ml
0.94
18
49
63
204
3.19
15.66
1.3
1.2
49.86
43.33
u/ml
0.10
17
18
769
6112
1.60
15.53
11.3
8.7
4.12
4.14
e9/l
0.08
694
5335
82
316
2.70
14.94
2.1
1.9
—
—
—
0
0
45
124
3.72
14.35
1.3
1.2
38.48
57.11
u/ml
—
6
7
630
4883
1.54
13.45
6.3
5.8
1.21
1.21
mmol/l
0.36
586
4450
916
7818
1.53
11.70
5.1
4.0
14.81
12.85
mm/h
2.92
862
7187
631
5001
1.49
11.49
7.7
5.5
57.87
57.50
%
0.35
605
4679
638
5078
1.49
11.31
8.0
5.8
26.75
27.39
%
0.81
610
4755
263
1732
1.64
10.95
3.1
3.2
0.83
0.82
mmol/l
0.59
248
1621
559
4358
1.48
10.86
2.5
2.2
79.73
77.39
nmol/l
1.07
506
3867
687
5608
1.46
10.36
6.9
6.2
10.47
11.63
umol/l
2.10
654
5330
380
2759
1.52
10.33
2.6
2.2
2.95
3.02
mg/l
0.17
327
2322
661
5364
1.45
10.24
6.7
6.6
1.21
1.21
mmol/l
0.15
569
4562
118
626
1.97
10.17
1.4
1.2
559.02
177.09
u/ml
1.20
109
576
939
8229
1.46
9.13
9.8
7.4
78.60
79.20
u/l
0.16
899
7728
430
3268
1.46
9.13
2.2
2.1
201.33
220.29
u/l
0.21
407
3077
230
1530
1.61
9.07
2.8
2.4
2.34
2.32
g/l
0.21
215
1413
187
1185
1.67
8.94
2.7
2.2
150.54
124.68
ug/g
0.58
147
949
567
4568
1.42
8.65
3.4
2.7
144.83
132.64
ug/l
0.50
530
4178
278
1965
1.52
8.35
1.4
1.4
2.49
2.52
g/l
0.07
150
1199
571
4635
1.40
8.21
5.8
4.7
35.03
35.24
g/l
0.38
534
4315
305
2207
1.49
8.17
1.3
1.2
1.77
1.60
u/ml
0.09
70
599
212
1428
1.57
7.88
3.0
2.4
21.11
22.51
%
0.81
190
1214
363
2747
1.44
7.66
3.1
2.6
1536.05
6742.02
umol/l
3.08
312
2382
242
1691
1.53
7.62
1.3
1.3
16.23
13.72
u/ml
0.14
86
652
132
796
1.73
7.57
1.9
1.6
—
—
—
0
0
812
7045
1.38
7.55
5.6
4.5
177.63
2722.47
e6/l
—
8
111
735
6324
1.36
6.93
5.0
4.9
6.77
6.74
mmol/l
0.15
697
5932
237
1681
1.50
6.91
2.8
2.4
12.31
12.91
umol/l
0.65
223
1551
55
261
2.15
6.46
2.0
1.8
6259.02
14011.75
e6/l
1.60
41
193
62
310
2.05
6.37
1.7
1.6
0.09
22.34
iu/ml
0.49
12
54
421
3364
1.37
6.25
2.9
2.5
52.60
82.81
u/l
0.69
390
3117
59
294
2.05
6.13
1.7
1.4
—
—
—
0
0
182
1252
1.52
6.11
2.0
1.7
—
—
—
0
0
151
997
1.58
6.09
2.8
2.3
39.06
36.59
u/l
0.17
124
839
245
1793
1.45
6.05
2.1
1.8
—
—
—
0
0
242
1770
1.45
5.99
1.3
1.3
40.03
34.71
iu/ml
0.26
83
577
408
3272
1.35
5.85
3.3
3.0
7.62
7.50
mmol/l
0.22
360
2753
281
2125
1.41
5.77
1.9
1.7
1096.29
1192.82
nmol/l
1.08
219
1583
33
133
2.52
5.64
1.8
1.6
59.19
62.21
%
0.14
16
88
400
3213
1.35
5.64
3.2
3.0
1690.68
1526.23
ng/l
0.32
348
2743
531
4445
1.32
5.63
2.2
2.0
94.40
94.53
pmol/l
0.02
277
2277
151
1021
1.54
5.49
2.2
2.2
0.21
0.21
g/l
0.06
136
948
179
1259
1.49
5.40
2.0
1.8
—
—
—
0
0
329
2582
1.36
5.35
2.7
2.3
—
—
—
0
0
119
767
1.60
5.32
1.6
1.8
—
—
—
0
0
594
5107
1.29
4.99
15.9
15.3
1.26
1.29
inr
0.25
154
1477
443
3666
1.31
4.96
3.5
3.4
2.35
2.35
mmol/l
0.08
378
3209
140
958
1.51
4.82
2.5
2.1
369.24
377.33
nmol/l
0.17
131
871
174
1245
1.46
4.81
5.8
8.1
5.09
5.12
kpa
0.12
162
1194
174
1246
1.45
4.79
5.8
8.1
11.79
12.05
kpa
0.29
163
1197
127
853
1.54
4.77
1.7
1.8
—
—
—
0
0
68
390
1.78
4.71
2.1
2.1
214.36
476.61
ug/l
1.18
61
367
240
1827
1.38
4.68
3.1
2.7
0.87
1.09
e6/l
0.75
136
1030
701
6188
1.28
4.66
3.0
2.9
—
—
—
0
0
400
3292
1.31
4.60
4.1
3.7
10.91
7.97
mg/mmol
0.46
271
2066
269
2100
1.35
4.46
4.1
3.8
592.29
324.23
ng/l
0.24
211
1661
172
1246
1.44
4.45
5.9
8.1
0.84
1.25
mmol/l
0.54
134
989
192
1421
1.41
4.41
6.1
5.2
1.04
1.03
mmol/l
0.08
183
1306
214
1615
1.39
4.39
1.6
1.5
—
—
—
0
0
164
1186
1.44
4.29
4.0
4.0
241.57
249.90
u/l
0.34
150
1119
366
3004
1.30
4.25
3.8
3.1
0.56
0.54
e6/l
0.04
284
2297
450
3793
1.28
4.25
4.4
3.6
191.86
121.08
e6/l
0.19
323
2723
135
948
1.47
4.12
5.7
6.9
1.28
1.39
mmol/l
0.97
130
922
589
5142
1.26
4.12
4.3
3.6
0.00
0.00
estimate
0.75
118
1050
594
5198
1.25
4.04
4.3
3.6
0.00
0.01
estimate
0.80
110
947
1115
10521
1.34
4.04
20.7
14.7
23.40
24.91
mg/l
0.78
944
8396
492
4223
1.26
3.93
4.1
3.8
34.59
50.74
ng/l
0.71
341
2984
62
367
1.72
3.90
2.4
2.9
—
—
—
0
0
142
1018
1.44
3.90
3.2
3.3
2.01
2.15
mmol/l
0.15
124
828
585
5128
1.25
3.87
5.6
4.9
0.00
0.00
estimate
0.50
113
978
32
152
2.13
3.86
1.2
1.1
0.97
2.54
u/ml
0.97
20
77
51
286
1.81
3.85
1.1
1.2
—
—
—
0
0
877
8050
1.25
3.80
4.6
4.0
14.86
14.82
pmol/l
0.17
816
7290
257
2043
1.32
3.73
3.7
3.0
2.47
2.46
mmol/l
0.79
217
1789
51
289
1.79
3.73
1.1
1.2
—
—
—
0
0
26
115
2.29
3.72
1.4
1.4
19878.24
95022.75
e6/l
0.67
17
81
25
109
2.32
3.70
1.1
1.0
1.91
3.54
u/ml
0.55
14
45
284
2294
1.30
3.67
2.9
2.5
5.34
5.86
e6/l
0.24
257
2075
99
673
1.51
3.57
7.0
9.6
93.13
94.00
%
0.49
99
668
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
59
355
1.69
3.53
2.5
2.7
0.30
0.35
u/ml
0.79
43
199
754
6842
1.23
3.48
3.6
3.2
55.83
51.63
u/l
0.51
710
6374
15
52
2.91
3.47
1.4
2.9
488.67
1406.60
u/ml
1.13
15
52
129
931
1.43
3.44
2.2
2.4
6.90
6.58
ug/l
0.08
106
815
67
421
1.62
3.40
3.8
3.8
24.54
24.91
mmol/l
0.43
62
394
115
814
1.45
3.40
3.7
3.5
94.52
87.11
ng/l
0.37
100
706
97
665
1.49
3.37
3.9
3.5
1.03
1.91
mmol/l
1.39
77
491
388
3294
1.25
3.31
3.9
3.2
39.31
94.16
e6/l
1.35
304
2547
84
561
1.53
3.30
7.0
10.1
23.93
24.45
mmol/l
0.83
78
545
18
71
2.56
3.30
1.2
1.1
—
—
—
0
0
95
654
1.49
3.24
1.5
1.5
—
—
—
0
0
51
303
1.71
3.22
1.7
1.7
—
—
—
0
0
18
72
2.52
3.21
1.2
1.1
—
—
—
0
0
28
137
2.07
3.18
1.5
1.3
—
—
—
0
0
97
674
1.47
3.17
7.1
9.4
0.65
0.68
%
0.27
97
668
74
486
1.55
3.15
1.6
1.7
1.65
1.56
g/l
0.41
56
428
28
138
2.05
3.12
1.5
1.3
—
—
—
0
0
28
138
2.05
3.12
1.5
1.3
—
—
—
0
0
285
2353
1.27
3.07
1.8
1.7
1.30
1.12
mg/l
0.44
221
1807
97
680
1.46
3.04
6.6
9.4
1.41
1.34
%
0.35
97
674
309
2580
1.26
3.02
1.6
1.5
19.65
20.86
nmol/l
0.79
271
2183
1026
9684
1.25
3.00
5.4
4.7
4.62
2.04
mu/l
0.46
953
8824
121
888
1.40
2.96
2.0
2.8
66.40
66.84
g/l
0.23
107
808
14
52
2.71
2.89
1.1
1.5
6.12
7.02
ug/l
0.26
14
41
6
9
6.69
2.87
1.8
1.1
—
—
—
0
0
27
136
2.01
2.86
1.5
1.3
—
—
—
0
0
27
136
2.01
2.86
1.5
1.3
—
—
—
0
0
98
699
1.43
2.82
2.3
2.5
28.30
23.48
au/ml
—
5
46
31
165
1.90
2.82
1.3
1.4
127.43
113.17
u/ml
—
7
29
27
137
1.99
2.81
1.5
1.3
—
—
—
0
0
17
71
2.41
2.80
1.2
1.1
—
—
—
0
0
326
2761
1.24
2.79
4.8
3.9
0.00
0.01
estimate
0.88
105
945
17
72
2.38
2.73
1.2
1.1
—
—
—
0
0
17
72
2.38
2.73
1.2
1.1
—
—
—
0
0
158
1229
1.32
2.69
2.3
2.5
1.75
1.81
%
0.40
139
1085
159
1238
1.32
2.68
3.5
2.7
8.33
8.55
umol/l
0.03
136
1082
92
656
1.43
2.67
2.0
1.6
—
—
—
0
0
40
236
1.72
2.63
1.5
1.3
—
—
—
0
0
25
127
1.99
2.61
1.1
1.0
0.48
1.63
u/ml
1.27
15
60
396
3447
1.21
2.58
4.4
3.2
32.92
33.31
u/l
0.04
375
3281
212
1726
1.27
2.56
3.3
2.9
2.58
2.35
e6/l
0.14
112
934
19
88
2.18
2.51
2.0
2.2
—
—
—
0
0
124
941
1.35
2.50
7.4
6.9
10.97
10.12
mmol/l
0.61
119
888
7
16
4.39
2.47
1.4
1.1
99.14
104.38
%
—
7
16
107
795
1.38
2.47
3.0
2.7
10.89
10.76
g/l
0.10
101
729
60
878
0.67
2.44
1.6
1.8
—
—
—
0
0
52
338
1.56
2.38
3.0
3.4
39.78
70.95
mg/l
0.93
40
276
52
339
1.56
2.35
3.0
3.4
36.44
39.53
mg/l
0.10
40
277
21
105
2.02
2.31
1.1
1.0
1.19
4.67
u/ml
1.25
12
36
18
86
2.11
2.23
1.1
1.0
0.05
0.32
u/ml
—
9
25
20
100
2.02
2.21
1.6
1.4
27.99
31.23
%
—
9
64
59
403
1.49
2.18
1.7
2.3
2.98
3.01
g/l
0.07
50
361
6
14
4.30
2.15
1.3
1.4
—
—
—
0
0
16
74
2.18
2.15
2.8
2.8
37.89
40.46
%
—
9
43
1025
9783
1.20
2.14
6.7
5.7
40.86
40.03
mmol/mol
1.97
955
9023
47
307
1.55
2.13
1.9
2.4
0.00
0.00
g/l
-0.00
40
281
319
2773
1.20
2.07
1.7
1.7
1.38
1.39
mmol/l
0.08
287
2326
49
326
1.52
2.06
1.9
2.4
0.00
0.02
g/l
0.50
42
299
7
20
3.51
2.05
1.3
1.2
—
—
—
0
0
47
311
1.53
2.03
1.4
1.5
297.07
285.72
ug/g
0.12
28
182
552
5031
1.16
2.02
2.9
2.6
—
—
—
0
0
264
2262
1.21
2.00
4.8
4.0
1.02
1.02
kg/l
0.14
34
344
84
624
1.37
1.98
3.1
3.4
4.29
4.51
pmol/l
1.12
68
549
29
171
1.71
1.97
1.2
1.2
—
—
—
0
0
7
21
3.35
1.96
1.1
1.4
—
—
—
0
0
57
396
1.46
1.96
1.7
2.3
10.58
10.61
g/l
0.01
48
353
49
330
1.50
1.96
3.7
4.0
3.88
3.91
mmol/l
0.15
49
324
46
306
1.52
1.95
1.9
2.4
0.00
0.00
g/l
-0.00
39
281
1135
10969
1.22
1.90
22.9
17.0
3.98
3.98
mmol/l
0.09
1112
10649
118
930
1.29
1.88
3.9
2.9
182.06
208.20
ng/l
0.43
111
855
53
367
1.46
1.86
1.9
2.5
0.57
1.08
g/l
0.52
43
322
50
343
1.48
1.84
1.8
2.3
36.98
37.79
g/l
0.38
41
301
39
255
1.55
1.80
1.5
1.3
—
—
—
0
0
1131
10943
1.20
1.78
22.7
16.9
139.47
139.64
mmol/l
1.28
1110
10640
11
47
2.35
1.78
1.0
1.0
—
—
—
0
0
31
194
1.61
1.72
1.2
1.2
—
—
—
0
0
5
13
3.86
1.71
1.0
1.1
—
—
—
0
0
5
13
3.86
1.71
1.0
1.1
—
—
—
0
0
59
426
1.40
1.68
1.7
2.2
3.81
3.62
g/l
0.60
50
385
59
427
1.40
1.67
1.7
2.2
7.16
7.47
g/l
1.00
50
385
59
427
1.40
1.67
1.7
2.2
—
—
—
0
0
62
454
1.38
1.64
1.8
2.0
44.87
38.74
u/l
1.09
56
401
1037
9981
1.17
1.63
18.5
13.6
79.06
79.35
ml/min/173m2
0.15
865
8268
19
105
1.82
1.63
2.7
2.3
—
—
—
0
0
144
1187
1.24
1.61
1.8
1.8
1.65
1.52
%
0.90
120
1015
1151
11178
1.20
1.61
14.3
10.3
25.92
26.00
u/l
0.05
1122
10767
35
231
1.53
1.58
1.8
1.3
—
—
—
0
0
35
231
1.53
1.58
1.8
1.3
—
—
—
0
0
29
183
1.60
1.58
1.2
1.2
285.32
287.59
u/ml
0.02
22
107
34
223
1.54
1.58
2.3
1.5
—
—
—
0
0
64
475
1.36
1.57
1.0
1.0
—
—
—
0
0
19
107
1.79
1.55
3.7
4.3
—
—
—
0
0
71
538
1.34
1.53
2.6
3.2
25.57
25.24
mmol/l
0.37
71
520
30
193
1.57
1.52
1.4
2.0
4.04
5.05
mmol/24h
1.48
25
172
17
93
1.84
1.52
1.2
1.0
—
—
—
0
0
6
21
2.87
1.50
1.3
1.0
—
—
—
0
0
36
243
1.49
1.48
2.2
2.1
120.83
129.09
g/l
1.21
23
177
10
45
2.23
1.46
2.5
2.7
45170.00
40920.00
ug/l
—
10
45
16
87
1.85
1.46
1.0
1.2
—
—
u/ml
—
0
0
10
201
0.49
1.44
1.4
1.5
—
—
—
0
0
13
66
1.98
1.43
2.2
2.0
—
—
—
0
0
12
60
2.01
1.38
1.4
1.8
14.27
19.60
nmol/l
2.12
12
54
139
1163
1.22
1.38
3.1
4.1
3.52
22.83
ug/l
1.92
114
964
18
104
1.74
1.37
2.2
1.5
—
—
—
0
0
21
127
1.66
1.37
2.0
2.2
48.25
27.57
mg/l
—
8
32
21
128
1.65
1.33
1.4
1.4
—
—
—
0
0
263
2336
1.16
1.31
1.9
1.7
35931155.45
32039769.40
pmol/l
0.04
231
1932
12
62
1.94
1.28
1.2
1.3
—
—
—
0
0
12
62
1.94
1.28
1.2
1.3
—
—
—
0
0
10
48
2.09
1.28
1.0
1.0
—
—
—
0
0
1088
10571
1.15
1.25
5.5
4.9
2.67
2.74
mmol/l
1.73
1006
9698
6
25
2.41
1.24
1.0
1.1
—
—
—
0
0
8
36
2.23
1.24
1.0
1.1
—
—
—
0
0
22
139
1.59
1.23
1.0
1.1
—
—
—
0
0
943
9083
1.13
1.23
24.5
17.4
15.16
15.07
%
0.17
934
8902
1057
10255
1.14
1.22
5.1
4.5
6.06
5.97
mmol/l
1.18
973
9281
44
324
1.37
1.19
1.6
1.6
—
—
—
0
0
430
3971
1.12
1.18
4.6
3.8
—
—
—
0
0
64
500
1.29
1.17
1.3
1.3
—
—
—
0
0
8
39
2.06
1.15
7.7
4.1
—
—
—
0
0
103
854
1.22
1.15
3.8
2.6
60.56
66.01
ml/min/173m2
1.01
48
348
1025
9939
1.13
1.14
4.4
3.9
1.35
1.30
mmol/l
1.20
943
9049
11
58
1.90
1.12
2.5
1.5
—
—
—
0
0
11
58
1.90
1.12
2.5
1.5
—
—
—
0
0
1065
10358
1.13
1.10
4.9
4.4
4.57
4.65
mmol/l
1.82
989
9573
5
21
2.39
1.09
1.8
1.3
—
—
—
0
0
35
253
1.39
1.07
1.1
1.1
—
—
—
0
0
18
113
1.60
1.06
2.2
1.5
—
—
—
0
0
19
122
1.57
1.02
2.1
1.7
—
—
—
0
0
85
701
1.23
1.02
1.3
1.2
81.19
140.53
iu/ml
1.32
27
279
105
886
1.20
1.00
3.9
3.7
1.23
1.23
mmol/l
0.63
93
769
17
107
1.60
1.00
1.1
1.1
—
—
—
0
0
27
189
1.44
0.99
2.4
1.6
—
—
—
0
0
35
257
1.37
0.99
1.4
1.2
—
—
—
0
0
23
156
1.48
0.99
1.2
1.2
2.29
6.80
u/ml
—
7
61
1056
10287
1.12
0.99
4.8
4.4
1.45
1.47
mmol/l
1.04
969
9431
51
398
1.29
0.97
1.4
1.3
20.91
30.66
iu/l
1.68
46
343
0
31
0.00
0.96
0.0
4.4
—
75.20
—
0
25
150
1311
1.16
0.96
8.4
7.0
—
—
—
0
0
35
259
1.36
0.95
2.1
1.6
—
—
—
0
0
34
251
1.36
0.94
1.6
3.1
28.79
34.47
umol/l
1.11
29
226
62
506
1.24
0.85
3.2
3.7
49.21
47.68
%
0.20
62
499
6
31
1.94
0.84
1.0
1.1
—
—
—
0
0
8
45
1.78
0.84
1.1
1.0
—
—
—
0
0
24
171
1.41
0.83
2.1
1.5
—
—
—
0
0
24
171
1.41
0.83
2.1
1.5
—
—
—
0
0
8
46
1.74
0.82
3.0
1.5
—
—
—
0
0
8
46
1.74
0.82
3.0
1.5
—
—
—
0
0
8
46
1.74
0.82
3.0
1.5
—
—
—
0
0
32
241
1.34
0.81
1.8
2.0
3604.43
3039.30
u/l
0.09
12
92
50
401
1.26
0.80
2.2
1.7
—
—
—
0
0
33
251
1.32
0.79
2.2
1.6
—
—
—
0
0
8
48
1.67
0.78
1.6
2.3
—
—
—
0
0
11
66
1.67
0.78
1.7
1.2
—
—
—
0
0
11
175
0.63
0.78
1.5
1.4
—
—
—
0
0
11
175
0.63
0.78
1.5
1.4
—
—
—
0
0
14
90
1.56
0.78
1.4
1.4
—
—
—
0
0
14
90
1.56
0.78
1.1
1.1
—
—
—
0
0
11
174
0.63
0.77
1.4
1.4
—
—
—
0
0
11
174
0.63
0.77
1.5
1.4
—
—
—
0
0
30
226
1.33
0.76
1.8
1.5
—
—
—
0
0
6
34
1.77
0.76
1.5
1.2
12.10
8.67
ug/l
—
6
34
22
158
1.40
0.74
1.1
1.2
2.00
2.32
u/ml
—
9
40
51
415
1.24
0.74
4.6
3.3
125.84
9426.37
u/ml
0.78
44
353
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
5
25
2.00
0.72
1.6
1.3
0.94
2.14
mmol/l
—
5
25
10
60
1.67
0.72
2.0
1.6
—
—
—
0
0
10
60
1.67
0.72
2.0
1.6
—
—
—
0
0
17
117
1.46
0.72
1.8
1.4
282.18
278.78
mosm/kgh2o
0.25
11
85
1184
11663
1.12
0.71
30.0
21.5
39.93
39.79
%
0.34
1111
10874
24
177
1.36
0.71
2.2
1.9
62.77
60.83
%
0.16
24
177
33
256
1.30
0.70
1.5
1.6
—
—
—
0
0
73
620
1.19
0.70
6.4
7.7
24.68
25.01
mmol/l
0.41
73
614
18
251
0.71
0.69
3.4
3.3
7.23
7.72
mmol/l
0.43
18
246
40
320
1.26
0.68
1.6
1.8
—
—
—
0
0
15
102
1.48
0.67
2.1
2.2
—
—
—
0
0
145
1303
1.13
0.67
4.4
4.5
32.34
32.36
%
0.01
110
877
1184
11671
1.12
0.66
29.8
21.4
6.87
6.77
e9/l
0.84
1160
11325
1184
11671
1.12
0.66
29.8
21.4
4.43
4.46
e12/l
0.93
1160
11326
13
86
1.52
0.66
1.0
1.2
—
—
—
0
0
18
128
1.41
0.65
1.2
1.4
42.76
26.34
u/l
0.75
13
103
40
322
1.25
0.65
1.4
1.3
—
—
—
0
0
21
154
1.37
0.65
1.5
1.5
—
—
—
0
0
1184
11674
1.11
0.65
30.0
21.5
133.70
134.37
g/l
0.85
1171
11478
1183
11664
1.11
0.65
29.9
21.4
252.28
249.53
e9/l
0.73
1158
11359
5
29
1.73
0.64
1.4
1.3
—
—
—
0
0
14
96
1.46
0.61
2.1
1.4
—
—
—
0
0
14
96
1.46
0.61
2.1
1.4
—
—
—
0
0
14
96
1.46
0.61
2.1
1.4
—
—
—
0
0
28
218
1.29
0.60
1.4
1.2
10.71
10.78
u/l
0.01
23
179
20
265
0.75
0.58
3.2
3.2
1.65
1.59
mmol/l
0.21
20
260
10
64
1.57
0.58
1.0
1.1
—
—
—
0
0
7
114
0.61
0.58
4.1
2.1
13.00
13.18
%
—
7
114
20
149
1.35
0.58
1.9
1.6
—
—
—
0
0
6
35
1.72
0.57
1.3
1.8
—
—
—
0
0
6
35
1.72
0.57
2.2
2.5
26.85
18.72
ug/l
—
6
29
13
184
0.70
0.57
1.4
1.5
—
—
—
0
0
6
36
1.67
0.56
1.3
1.1
—
—
—
0
0
6
37
1.62
0.55
1.3
1.5
—
—
—
0
0
52
440
1.19
0.55
2.6
1.8
—
—
—
0
0
10
65
1.54
0.55
1.0
1.2
—
—
—
0
0
13
91
1.43
0.53
1.8
1.7
—
—
—
0
0
12
83
1.45
0.52
1.8
1.5
0.84
1.01
g/l
1.78
12
83
6
40
1.50
0.51
1.7
1.8
29.07
54.16
ug/l
—
6
40
7
45
1.56
0.49
1.4
1.3
—
—
—
0
0
11
76
1.45
0.48
1.5
1.5
11.65
13.29
umol/l
0.37
11
71
22
173
1.28
0.46
2.0
1.5
—
—
—
0
0
5
83
0.60
0.45
1.0
1.5
82.20
83.47
umol/l
—
5
83
20
157
1.28
0.43
1.2
1.1
—
12.36
—
0
10
28
230
1.22
0.42
2.9
2.5
14.89
16.06
%
0.64
14
120
6
93
0.64
0.42
2.7
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
25
304
0.82
0.41
1.3
1.5
—
—
—
0
0
8
60
1.34
0.40
1.0
1.2
—
—
—
0
0
26
214
1.22
0.39
3.4
3.2
4.08
4.29
e9/l
0.18
26
214
8
61
1.31
0.39
1.3
1.2
—
—
—
0
0
123
1137
1.09
0.38
3.2
3.4
—
—
—
0
0
5
36
1.39
0.38
1.0
1.2
125.40
108.27
%
—
5
30
15
192
0.78
0.38
1.3
1.6
—
—
—
0
0
9
67
1.35
0.38
1.2
1.3
1.59
1.55
g/l
—
9
67
9
70
1.29
0.36
1.8
2.0
—
—
—
0
0
9
70
1.29
0.36
2.2
1.6
—
—
—
0
0
24
286
0.84
0.34
1.3
1.2
—
—
—
0
0
18
145
1.24
0.33
1.6
1.5
—
—
—
0
0
11
83
1.33
0.32
1.2
2.3
5.32
5.33
umol/l
—
5
58
10
75
1.34
0.30
2.0
1.5
—
—
—
0
0
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
19
158
1.21
0.28
1.1
1.1
—
—
—
0
0
20
237
0.84
0.28
2.4
1.4
7.93
25.16
e6/l
0.63
15
188
20
237
0.84
0.28
2.4
1.5
279.47
908.83
e6/l
0.52
15
194
26
224
1.16
0.27
3.4
3.4
54.00
57.81
%
0.78
26
224
9
76
1.19
0.24
1.1
1.4
1.94
2.95
ug/l
—
9
63
22
189
1.17
0.24
1.5
1.5
—
—
—
0
0
25
218
1.15
0.23
2.7
3.4
8.94
1694.42
u/ml
0.84
20
206
21
243
0.86
0.23
5.2
3.8
20.43
28.45
mg/l
0.58
11
166
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
40
441
0.90
0.22
2.1
1.7
—
—
—
0
0
13
107
1.22
0.21
1.8
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
18
154
1.17
0.21
5.6
5.1
406.85
362.29
umol/l
0.54
13
137
30
268
1.12
0.20
1.4
1.3
284.63
222.85
miu/ml
0.32
14
125
28
249
1.13
0.20
5.7
4.9
5.05
5.05
kpa
0.00
28
244
0
14
0.00
0.20
0.0
2.4
—
0.57
—
0
14
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
48
1.25
0.20
1.0
1.3
—
—
—
0
0
33
298
1.11
0.19
3.7
3.0
25.17
24.82
mmol/l
0.22
33
293
30
270
1.11
0.19
1.8
2.4
34.88
95.05
ug/min
1.43
14
154
19
166
1.15
0.18
1.6
1.5
—
—
—
0
0
7
59
1.19
0.18
1.6
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
59
1.19
0.18
1.1
1.2
—
—
—
0
0
7
59
1.19
0.18
1.6
1.3
—
—
—
0
0
5
67
0.75
0.17
1.0
1.1
—
—
—
0
0
12
101
1.19
0.16
2.6
1.7
—
—
—
0
0
29
266
1.09
0.14
2.6
1.8
2.57
4.75
iu/l
1.95
12
89
10
117
0.85
0.13
1.0
1.1
—
—
—
0
0
16
142
1.13
0.12
1.1
1.0
—
—
—
0
0
13
114
1.14
0.12
1.8
1.6
—
—
—
0
0
13
114
1.14
0.12
1.8
1.6
—
—
—
0
0
16
143
1.12
0.11
1.1
1.1
—
—
—
0
0
14
125
1.12
0.10
1.6
1.6
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
108.80
95.92
%
—
5
37
350
3453
1.02
0.09
4.7
4.8
4.97
3.17
ug/l
0.46
309
3084
202
1982
1.02
0.09
3.3
3.0
0.63
0.79
ug/l
2.81
132
1310
5
48
1.04
0.09
1.0
1.1
177.30
235.15
iu/ml
—
5
48
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
6
54
1.11
0.09
1.3
1.4
—
—
—
0
0
6
54
1.11
0.09
1.7
2.4
—
—
—
0
0
6
55
1.09
0.09
1.3
1.3
116.52
163.00
pmol/l
—
6
55
12
134
0.89
0.08
1.0
1.0
2.52
2.06
u/ml
—
5
56
7
80
0.87
0.07
1.3
1.1
188.86
244.90
mg/l
—
7
70
273
2764
0.98
0.07
4.5
4.2
21.59
21.48
%
0.04
122
1323
28
265
1.06
0.07
1.9
1.3
434.14
508.56
mg/l
0.74
28
250
10
89
1.12
0.07
1.4
1.2
—
—
—
0
0
25
236
1.06
0.06
1.8
1.2
3.93
3.76
mmol/l
0.32
25
222
9
100
0.90
0.06
1.0
1.1
—
—
—
0
0
69
671
1.03
0.06
2.2
2.1
11.81
12.50
nmol/l
0.32
62
593
10
111
0.90
0.06
1.0
1.1
—
—
—
0
0
28
266
1.05
0.06
3.9
2.9
8.13
7.99
kpa
0.23
28
259
10
110
0.91
0.05
1.2
1.5
—
—
—
0
0
12
129
0.93
0.03
1.5
1.4
1382.43
1550.95
e6/l
—
7
88
34
347
0.98
0.01
2.1
1.6
—
—
—
0
0
11
116
0.95
0.00
1.5
1.3
23792.40
91831.93
e6/l
—
5
68
32
324
0.99
0.00
1.7
1.4
—
—
—
0
0
156
1561
1.00
0.00
1.5
1.4
—
—
—
0
0
14
143
0.98
0.00
1.4
1.6
—
—
—
0
0
33
333
0.99
0.00
1.5
1.4
—
—
—
0
0
38
377
1.01
0.00
1.6
1.8
7.47
3.09
mg/l
0.45
29
280
15
155
0.97
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
-0.00
1.1
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.8
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
2.00
—
0
6
5
49
1.02
-0.00
1.8
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_OTHACUSKINSUN and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_OTHACUSKINSUN | 0.926 [0.79, 1.09] | 0.361 |
| Birth year | 0.998 [0.99, 1.01] | 0.614 |
During the follow-up period (1.1.1998 — 31.12.2019), 231 out of 2255 females with L12_OTHACUSKINSUN died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_OTHACUSKINSUN | 1.147 [0.96, 1.37] | 0.129 |
| Birth year | 0.99 [0.98, 1.0] | 0.046 |
During the follow-up period (1.1.1998 — 31.12.2019), 282 out of 1251 males with L12_OTHACUSKINSUN died.
Mortality risk
Mortality risk for people of age
years, who have L12_OTHACUSKINSUN.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.099% | 0.216% |
| 5 | 0.486% | 1.37% |
| 10 | 1.451% | 3.59% |
| 15 | 2.824% | 6.989% |
| 20 | 5.077% | 12.099% |
Relationships between endpoints
↥Index endpoint: L12_OTHACUSKINSUN – Other acute skin changes due to ultraviolet radiation
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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