Photocontact dermatitis [berloque dermatitis]

L12_PHOTOCONTDERMAT

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L56.2 Cause of death: ICD-10 — L56.2 2 out of 7 registries used, show all original rules.	52
4. Check minimum number of events None	52
5. Include endpoints None	52
6. Filter based on genotype QC (FinnGen only)	52

Control definitions (FinnGen only)

Control exclude: L12_RADIATIONRELATEDSKIN

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L56
Name in latin: Photodermatitis ex contactu

NAME	L12_PHOTOCONTDERMAT
CONTROL_EXCLUDE	L12_RADIATIONRELATEDSKIN
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L562
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L562
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Photocontact dermatitis [berloque dermatitis] based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	381	248	133
Only index persons	345	228	117
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.01	0.00
Median age at first event (years)
Whole population	-	52.24	47.31
Only index persons	51.85	53.39	48.84

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	52	35	17
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	50.90	52.71	47.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3029937) Albumin [Presence] in Urine by Test strip

107

2.22

1.87

6.0

4.0

0.0

estimate

—

(3037467) Urinalysis macro (dipstick) panel - Urine

285

2.24

1.77

5.9

4.6

—

(3026008) Bacteria identified in Urine by Culture

126

2.12

1.76

4.0

2.8

—

(40760892) CBC W Ordered Manual Differential panel - Blood

2.17

1.69

5.4

5.7

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

3.83

1.65

1.4

1.5

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

138

2.03

1.62

4.9

2.6

48.0

54.2

u/l

0.54

129

(40761536) Microorganisms panel - Urine sediment

2.83

1.58

2.9

3.3

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.94

1.48

1.7

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

164

1.86

1.33

5.1

3.7

19.9

27.3

ng/l

0.81

(3021447) Carbon dioxide [Partial pressure] in Venous blood

2.44

1.31

4.5

5.0

6.5

5.8

kpa

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

2.58

1.28

4.3

5.2

135.7

121.6

g/l

—

(3031040) Bacteria [#/volume] in Urine by Automated count

276

1.82

1.16

7.2

4.4

—

32.6

—

(3012544) pH of Venous blood

2.12

1.14

4.5

—

(3024354) Oxygen [Partial pressure] in Venous blood

2.37

1.13

4.7

3.3

4.6

4.4

kpa

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

2.40

1.06

4.8

5.2

27.7

24.8

mmol/l

—

(3000494) Fungus identified in Specimen by Culture

2.05

1.05

3.0

1.3

—

(3000492) Spirometry study

2.03

0.98

1.4

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

106

1.74

0.93

4.1

2.0

3.9

3.2

mg/l

0.33

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

2.01

0.92

2.9

2.1

0.2

g/l

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.88

0.91

2.0

2.5

12.6

13.4

umol/l

0.14

(3023368) Bacteria identified in Blood by Culture

108

1.70

0.87

4.4

4.1

—

(3020682) Albumin/Creatinine [Ratio] in Urine

117

1.67

0.86

5.6

4.1

1.9

9.3

mg/mmol

1.82

(3032080) INR in Blood by Coagulation assay

163

1.61

0.84

13.5

6.9

1.2

inr

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.79

0.83

2.9

1.6

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.86

0.83

2.1

2.6

2.4

2.5

g/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.88

0.82

2.2

2.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.70

0.76

2.3

—

(40758558) Short blood count panel - Blood

113

1.60

0.72

5.5

6.9

—

(3018418) pH of Serum or Plasma

123

1.57

0.69

2.1

4.3

7.4

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

188

1.51

0.69

4.8

2.7

79.9

90.9

ug/l

0.20

167

(3019060) Gas panel - Arterial blood

1.80

0.65

4.4

5.9

—

(3021601) Nitrite [Presence] in Urine by Test strip

210

1.48

0.63

7.4

5.7

0.0

estimate

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

431

1.94

0.63

27.9

14.3

16.4

21.0

mg/l

0.61

332

(3008898) HLA-B27 [Presence]

0.00

0.62

0.0

1.1

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.86

0.61

1.7

1.6

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

0.61

0.0

1.1

—

(40761535) Cells panel - Urine sediment

1.75

0.59

5.5

3.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.58

0.58

2.1

1.5

—

(42870588) Differential panel, method unspecified - Blood

137

1.48

0.58

7.7

5.6

—

(1761868) Lipid panel - Serum or Plasma

165

1.46

0.58

4.0

2.6

—

(3035350) Ketones [Presence] in Urine by Test strip

213

1.44

0.58

5.9

4.0

0.0

estimate

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.61

0.55

2.7

3.6

—

(3042936) Bacteria identified in Isolate by Culture

1.61

0.54

2.6

2.1

—

(3015736) pH of Urine

167

1.43

0.54

5.0

3.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

158

1.43

0.53

7.0

4.1

—

(40768804) Tissue Pathology biopsy report

177

1.42

0.53

1.8

1.9

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

149

1.43

0.52

4.8

3.3

25.3

26.4

u/l

0.20

140

(3007853) Bacteria identified in Skin by Aerobe culture

1.60

0.51

4.1

1.5

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.54

0.50

1.4

2.8

2.4

2.5

mmol/l

0.45

(3009261) Glucose [Presence] in Urine by Test strip

217

1.40

0.50

5.9

4.0

0.0

estimate

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

150

1.42

0.50

5.1

3.2

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

1.52

0.48

1.3

42.1

47.3

iu/ml

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.46

0.47

3.1

1.6

—

(4035726)

1.68

0.44

1.4

1.3

—

(3000991) Gas panel - Venous blood

1.62

0.43

5.4

9.9

—

(3013512) EKG study

116

1.41

0.43

7.0

4.2

—

(4010399)

1.52

0.41

1.0

1.4

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.41

0.0

1.2

—

(3003694) ABO and Rh group [Type] in Blood

117

1.40

0.41

1.5

1.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.39

0.40

1.8

1.4

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

1.39

0.33

10.3

3.4

18.6

205.2

ng/l

—

(21494755) Public health laboratory ask at order entry panel

1.40

0.33

1.4

1.3

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.34

0.32

4.9

3.2

4.5

6.7

umol/l

—

(3013707) Erythrocyte sedimentation rate by Westergren method

319

1.30

0.31

6.7

4.6

10.1

11.0

mm/h

0.21

293

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

201

1.26

0.28

4.3

3.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.28

0.27

2.7

1.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

116

1.28

0.25

5.9

4.0

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.28

0.23

18.8

9.4

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.2

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.0

—

0.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.2

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

1.1

—

(3007566) Smooth muscle Ab [Titer] in Serum

0.00

0.21

0.0

1.3

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.21

0.0

1.3

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.3

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.21

0.0

1.9

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.21

0.0

1.1

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.3

—

(36304419) Bacteria [Presence] in Urine

128

1.24

0.21

5.0

2.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.28

0.21

1.9

2.0

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

3.2

—

16.5

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.21

0.0

2.4

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.20

0.0

1.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.25

0.18

1.6

1.9

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

189

1.19

0.17

6.6

4.6

35.5

35.9

g/l

0.15

180

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

199

1.18

0.17

6.1

7.7

1.2

mmol/l

0.05

172

(3011397) Hemoglobin [Presence] in Urine by Test strip

103

1.21

0.15

5.7

3.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.12

0.10

1.4

1.6

—

(3044889) 12 lead EKG panel

305

1.13

0.10

4.2

3.6

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.07

0.10

2.2

1.9

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.82

0.09

1.8

1.5

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

458

1.27

0.09

27.9

15.4

71.3

76.6

umol/l

1.40

458

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.81

0.08

1.7

1.6

—

(3044640) Blood type and Crossmatch panel - Blood

138

1.12

0.07

1.7

2.1

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

309

0.93

0.03

3.4

3.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

167

0.94

0.01

4.3

2.0

93.5

101.5

pmol/l

0.38

(3009542) Hematocrit [Volume Fraction] of Blood

406

0.94

0.01

26.5

15.3

39.1

40.3

0.31

303

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

345

1.04

0.00

11.6

7.5

69.7

75.1

u/l

0.81

324

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(4146454)

0.00

0.0

2.8

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.8

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.7

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.0

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.3

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.1

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(4062490)

0.00

0.0

1.0

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.0

1.4

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.0

1.6

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.2

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.7

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.0

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.1

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.8

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

0.8

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.2

—

214.6

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

1.9

—

41.8

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.5

—

124.0

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.3

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.6

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.6

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.2

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

2.0

—

90.5

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.0

4.4

—

4.8

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

3.4

—

(3007368) IgG [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

40.6

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.0

4.4

—

10.3

—

(3010421) pH of Blood

0.00

0.0

4.5

—

7.4

—

(40768797) Stomach Pathology biopsy report

0.97

0.00

2.0

1.2

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

17.6

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.8

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3048689) Calprotectin [Mass/mass] in Stool

0.95

0.00

8.8

2.5

46.0

101.8

ug/g

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

1.6

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.4

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(4306422)

0.00

0.0

1.6

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.4

—

104.2

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_PHOTOCONTDERMAT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_PHOTOCONTDERMAT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_PHOTOCONTDERMAT – Photocontact dermatitis [berloque dermatitis]

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Photocontact dermatitis [berloque dermatitis]

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints