Testicular hypofunction

E4_TESTICHYPO

testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only males

226754

2. Check conditions

None

226754

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E29.1#
  • Hospital discharge: ICD-9 257[1-2]
  • Hospital discharge: ICD-8 2571
  • Cause of death: ICD-10 E29.1#
  • Cause of death: ICD-9 257[1-2]
  • Cause of death: ICD-8 2571
  • KELA reimbursements: KELA codes ANY
  • KELA reimbursements: ICD-10 E29.1#

3 out of 7 registries used, show all original rules.

1262

4. Check minimum number of events

None

1262

5. Include endpoints

None

1262

6. Filter based on genotype QC (FinnGen only)

1188

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E29
Name in latin
Hypofunctio testium

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4793 - 4793
Only index persons 4698 - 4698
Unadjusted period prevalence (%)
Whole population 0.13 - 0.13
Only index persons 0.18 - 0.18
Median age at first event (years)
Whole population - - 48.75
Only index persons - - 48.71

-FinnGen-

Key figures

All Female Male
Number of individuals 1188 - 1188
Unadjusted period prevalence (%) 0.54 - 0.54
Median age at first event (years) 52.42 - 52.42

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1262
Matched controls
12620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
243.3
307.7
1154
531
E29.1
ICD-10 Finland
Testicular hypofunction
761.5
307.7
1094
107
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
54.6
307.7
214
47
121
Kela drug reimbursment
Severe hypofunction of sexual glands
510.6
307.7
477
15
Y28
ICPC
Limited function/disability (Y)
46.1
210.6
125
30
A50
ICPC
General and Unspecified, Medication/prescr/renewal
11.8
180.7
197
194
A55
ICPC
General and Unspecified, Local injection/infiltration
19.7
167.0
133
75
WVA30, ,
SPAT
7.6
119.6
183
274
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
53.4
106.4
61
12
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
9.2
86.1
109
129
T99
ICPC
Endocr/metab/nutrit disease other
14.8
77.2
70
50
G47.3
ICD-10 Finland
Sleep apnoea
2.8
69.3
538
2614
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
63.0
60
*
KFC00
NOMESCO Finland
Unilateral orchiectomy
11.0
56.3
61
58
G03GA01
ATC
chorionic gonadotrophin; parenteral
104.9
55.3
60
6
R5140
NOMESCO Finland
Monitoring the use of the aid
3.0
48.8
261
1013
N48.4
ICD-10 Finland
Impotence of organic origin
4.6
47.3
118
275
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
4.7
44.7
109
249
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.2
40.8
526
3055
T28
ICPC
Limited function/disability (T)
12.1
40.5
41
35
N06AX11
ATC
mirtazapine; oral
2.2
39.0
467
2621
H03AA01
ATC
levothyroxine sodium; systemic
2.9
35.9
185
696
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
8.5
35.3
46
56
N05CF02
ATC
zolpidem; oral
2.5
34.7
256
1155
N02AX02
ATC
tramadol; systemic, rectal
2.1
34.7
603
3864
N03AX16
ATC
[U] pregabalin
2.3
34.4
321
1610
N06AX26
ATC
vortioxetine; oral
3.2
33.7
143
480
N62
ICD-10 Finland
Hypertrophy of breast
7.0
33.3
51
75
N06AB10
ATC
escitalopram; oral
2.4
33.2
296
1454
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
33.1
234
1033
N03AX12
ATC
[U] gabapentin; oral
2.5
31.9
234
1051
G04CA01
ATC
alfuzosin; oral
2.3
31.6
294
1467
WX723
NOMESCO Finland
CPAP therapy
3.5
31.5
117
361
H02AB09
ATC
hydrocortisone; systemic
8.8
31.5
40
47
N46
ICD-10 Finland
Male infertility
4.4
30.7
79
188
N05BA04
ATC
oxazepam; oral
2.2
30.4
306
1575
N06AX16
ATC
venlafaxine; oral
2.5
30.0
209
914
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.1
29.7
134
466
N06AX21
ATC
duloxetine; oral
2.8
29.7
166
650
R53
ICD-10 Finland
Malaise and fatigue
2.3
29.5
282
1418
N06AX12
ATC
bupropion; oral
2.9
29.4
149
553
R03AC02
ATC
salbutamol; inhalant
1.9
28.1
651
4498
M01AH05
ATC
etoricoxib; oral
2.0
27.9
852
6450
D75.1
ICD-10 Finland
Secondary polycythaemia
8.4
27.5
36
44
N05CF01
ATC
zopiclone; oral
2.0
27.4
378
2184
A02BC05
ATC
esomeprazole; systemic
1.9
27.3
500
3187
E29.9
ICD-10 Finland
Testicular dysfunction, unspecified
27.2
27.2
37
14
R01AD09
ATC
mometasone; nasal
1.9
27.1
563
3742
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
26.7
604
4118
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
26.2
616
4244
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
26.1
345
1959
J01MA02
ATC
ciprofloxacin; systemic
1.9
26.0
489
3132
J01FA10
ATC
azithromycin; systemic
1.9
25.9
704
5072
WX780
NOMESCO Finland
Remote monitoring CPAP
3.1
25.9
116
401
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
25.9
570
3843
T55
ICPC
Metabolic, Local injection/infiltration
33.8
25.6
33
10
N05AH04
ATC
quetiapine; oral
2.2
25.5
276
1452
-50
ICPC
Medication/prescr/renewal
4.3
25.5
67
162
R06.0
ICD-10 Finland
Dyspnoea
2.1
25.4
301
1638
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.5
25.3
89
265
N04BC05
ATC
pramipexole; oral
3.3
25.1
98
312
E66.01
ICD-10 Finland
Obesity due to excess calories
2.9
24.4
126
471
E66.00
ICD-10 Finland
Metabolic syndrome
3.0
23.6
109
383
Q98.0
ICD-10 Finland
Klinefelter syndrome karyotype 47,XXY
47.6
23.4
28
6
J01AA02
ATC
doxycycline; systemic
1.9
22.8
933
7505
N06AB04
ATC
citalopram; systemic
2.1
22.7
245
1282
S55
ICPC
Skin, Local injection/infiltration
20.5
21.8
32
16
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
21.4
393
2467
L02BG04
ATC
letrozole; oral
17.8
21.4
33
19
M03BX02
ATC
tizanidine; oral
1.8
21.3
815
6347
XKD00
NOMESCO Finland
Uroflowmetry
2.1
21.1
247
1330
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
20.8
247
1335
A02BC03
ATC
lansoprazole; oral
1.9
20.6
317
1876
R06AX27
ATC
desloratadine; oral
1.9
20.3
343
2090
R01AD12
ATC
fluticasone furoate; nasal
1.8
20.3
388
2459
T50
ICPC
Metabolic, Medication/prescr/renewal
33.1
20.2
26
8
J01DB01
ATC
cefalexin; oral
2.0
20.2
1045
8864
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.6
20.2
125
513
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
19.7
420
2745
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
19.7
181
885
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.6
19.5
67
196
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.4
19.5
72
221
M54.5
ICD-10 Finland
Low back pain
1.8
19.2
444
2967
ZXE00
NOMESCO Finland
One hour or less
1.8
19.1
417
2741
J01CA04
ATC
amoxicillin; systemic
1.9
19.0
998
8388
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.2
19.0
79
261
R01AD58
ATC
fluticasone, combinations; nasal
1.9
19.0
311
1872
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
18.8
299
1781
A02BC02
ATC
pantoprazole; systemic
1.7
18.8
790
6210
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
+∞
18.8
18
*
A02BC01
ATC
omeprazole; systemic
1.9
18.7
276
1604
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
19.1
18.7
28
15
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.9
18.6
298
1780
M79.6
ICD-10 Finland
Pain in limb
1.7
18.4
466
3187
Q98.4
ICD-10 Finland
Klinefelter syndrome, unspecified
44.7
18.3
22
5
N05BA12
ATC
alprazolam; oral
2.4
18.2
134
596
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
18.0
183
930
SPAT1262
SPAT
Handing over of treatment supplies
2.0
17.8
221
1210
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
17.8
359
2298
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
17.7
17
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.7
17.7
57
160
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
17.7
334
2096
UKC02
NOMESCO Finland
Cystoscopy
2.1
17.6
199
1052
N02BE01
ATC
paracetamol; systemic, rectal
2.0
17.5
1055
9109
J02AC01
ATC
fluconazole; systemic
1.9
17.5
245
1398
N06AX22
ATC
agomelatine; oral
4.2
17.1
45
109
H02AB04
ATC
methylprednisolone; systemic
2.2
17.1
161
794
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
17.0
385
2542
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
16.9
666
5087
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
16.9
274
1638
L02BG03
ATC
anastrozole; oral
64.2
16.8
19
*
N06AB06
ATC
sertraline; oral
2.2
16.8
147
704
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
16.7
225
1264
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
16.7
211
1161
E22.1
ICD-10 Finland
Hyperprolactinaemia
172.2
16.5
17
*
Y50
ICPC
Male Genital, Medication/prescr/renewal
20.4
16.4
24
12
R01AD08
ATC
fluticasone; nasal
1.8
16.3
345
2229
SPAT1254
SPAT
Administration of medicine
2.2
16.3
149
725
M48.0
ICD-10 Finland
Spinal stenosis
2.3
16.3
125
565
N06AB03
ATC
fluoxetine; oral
2.2
16.2
141
672
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
16.2
162
817
J01FA06
ATC
roxithromycin; oral
1.7
16.1
432
2979
L02BA01
ATC
tamoxifen; oral
18.8
16.0
24
13
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
16.0
238
1381
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
12.4
15.9
28
23
N40
ICD-10 Finland
Hyperplasia of prostate
1.8
15.9
324
2071
M01AB05
ATC
diclofenac; systemic, rectal
1.7
15.8
853
7000
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
15.8
282
1732
N05CD07
ATC
temazepam; oral
2.4
15.7
119
535
N02BF01
ATC
gabapentin; oral
2.4
15.7
108
465
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
15.7
190
1028
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
15.6
595
4473
R02
ICPC
Shortness of breath/dyspnoea
2.3
15.5
125
578
S50
ICPC
Skin, Medication/prescr/renewal
12.5
15.4
27
22
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
15.3
299
1884
M01AE02
ATC
naproxen; oral, rectal
1.6
15.3
651
5020
L03
ICPC
Low back symptom/complaint
1.8
15.1
290
1817
R03DC03
ATC
montelukast; oral
2.0
15.0
179
963
E66.8
ICD-10 Finland
Other obesity
2.9
15.0
72
259
J01MA12
ATC
levofloxacin; systemic
1.9
14.8
221
1282
E0000UV, ,
ATC
1.6
14.7
432
3033
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
14.6
151
771
H02AB06
ATC
prednisolone; systemic
1.6
14.5
529
3913
C07AA05
ATC
propranolol; systemic
1.9
14.5
222
1297
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
14.5
234
1391
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.1
14.5
145
731
J01EA01
ATC
trimethoprim; systemic
2.3
14.5
111
502
R06.5
ICD-10 Finland
Mouth breathing
2.0
14.5
169
902
M04AA01
ATC
allopurinol; systemic
2.0
14.4
164
866
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
14.3
295
1883
R51.80
ICD-10 Finland
Headache
2.0
14.3
164
869
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
14.3
100
434
J05AB11
ATC
valaciclovir; oral
2.1
14.2
145
736
P06
ICPC
Sleep disturbance
2.0
14.2
155
807
N06AB05
ATC
paroxetine; oral
2.6
14.2
85
343
WX320
NOMESCO Finland
Spinalanesthesy
1.8
14.1
235
1408
R50.9
ICD-10 Finland
Fever, unspecified
1.9
14.1
188
1049
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.4
14.1
101
443
E89.5
ICD-10 Finland
Postprocedural testicular hypofunction
54.0
13.8
16
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.2
13.8
123
592
C03CA01
ATC
furosemide; systemic
1.8
13.8
225
1340
Y05
ICPC
Scrotum/testis sympt/compl other
4.2
13.7
36
87
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.7
13.7
77
301
N06BA04
ATC
methylphenidate; oral
3.2
13.6
55
179
H01AC01
ATC
somatropin; parenteral
+∞
13.6
13
*
J05AB01
ATC
aciclovir; systemic
1.9
13.5
200
1155
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
13.5
638
4988
127
Kela drug reimbursment
Transplant complication
4.1
13.4
37
93
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.9
13.4
65
235
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.9
13.3
61
214
R03BA08
ATC
ciclesonide; inhalant
2.4
13.3
96
423
N05BA01
ATC
diazepam; systemic, rectal
2.0
13.2
151
798
R06AX22
ATC
ebastine; oral
1.9
13.2
184
1042
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
13.1
326
2183
J01AA04
ATC
lymecycline; systemic
2.0
13.1
151
802
L08
ICPC
Shoulder symptom/complaint
1.8
13.0
240
1481
M01AC06
ATC
meloxicam; systemic, rectal
1.6
13.0
389
2729
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
13.0
110
519
F51.0
ICD-10 Finland
Nonorganic insomnia
1.9
12.9
195
1132
E29.8
ICD-10 Finland
Other testicular dysfunction
22.8
12.9
18
8
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
12.8
314
2093
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.9
12.8
60
213
Z71.8
ICD-10 Finland
Other specified counselling
1.7
12.8
320
2145
J01FF01
ATC
clindamycin; systemic
1.7
12.7
324
2183
E30.09
ICD-10 Finland
Delayed puberty NOS
+∞
12.5
12
*
C10AA07
ATC
rosuvastatin; oral
1.6
12.5
380
2670
R06AE07
ATC
cetirizine; oral
1.6
12.5
455
3335
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.7
12.5
66
250
M54.1
ICD-10 Finland
Radiculopathy
3.0
12.5
56
194
M79.1
ICD-10 Finland
Myalgia
2.0
12.4
154
837
M02AA07
ATC
piroxicam; topical
1.6
12.4
353
2440
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
12.3
481
3582
C09CA06
ATC
candesartan; oral
1.7
12.2
270
1748
T29
ICPC
Endocr/metab/nutr sympt/compl other
4.3
12.2
31
73
UDC00
NOMESCO Finland
Ear microscopy
2.3
12.2
94
426
SPAT1094
SPAT
Continuous Positive Airway Pressure
4.5
12.2
29
65
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
12.1
102
479
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.5
12.1
74
301
S01GX01
ATC
cromoglicic acid; ophthalmic
1.8
12.1
187
1092
R52.2
ICD-10 Finland
Other chronic pain
3.1
12.0
51
171
XW000
NOMESCO Finland
Bone marrow biopsy
2.8
11.9
58
210
N02BF02
ATC
pregabalin; oral
2.5
11.9
76
316
P76
ICPC
Depressive disorder
2.4
11.9
81
347
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
11.9
202
1214
N06AA12
ATC
doxepin; systemic
2.8
11.9
59
216
N41.1
ICD-10 Finland
Chronic prostatitis
2.6
11.9
72
292
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
11.8
201
1208
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.7
11.8
37
102
L28
ICPC
Limited function/disability (L)
2.0
11.8
134
706
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
11.8
257
1656
M81.9
ICD-10 Finland
Osteoporosis, unspecified
5.0
11.7
25
51
Z01.2
ICD-10 Finland
Dental examination
1.5
11.6
502
3805
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.2
11.6
95
441
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
65.6
11.6
13
*
J01FA09
ATC
clarithromycin; systemic
1.6
11.5
345
2407
G04CA02
ATC
tamsulosin; oral
1.6
11.5
345
2407
E23.05
ICD-10 Finland
Lack of TSH
+∞
11.5
11
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
11.4
86
386
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
11.3
280
1863
C07AB07
ATC
bisoprolol; oral
1.5
11.3
483
3647
E29
ICD-10 Finland
Testicular dysfunction
15.2
11.3
18
12
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
11.3
48
161
DHB50
NOMESCO Finland
Turbinoplasty
2.8
11.3
57
211
KFH50
NOMESCO Finland
Insertion of prosthetic replacement for testis
17.2
11.2
17
10
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
11.2
335
2337
P01AB01
ATC
metronidazole; oral, rectal
1.6
11.1
352
2485
Y08
ICPC
Sexual function sympt/compl male
8.1
11.1
24
30
SBB10
NOMESCO Finland
Dental impressions
2.4
11.1
79
346
WX402
NOMESCO Finland
General anaesthesia
1.7
11.1
253
1650
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
11.0
456
3416
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
11.0
247
1602
N18.8
ICD-10 Finland
Other chronic renal failure
3.7
11.0
34
93
C08CA13
ATC
lercanidipine; oral
1.9
11.0
136
739
A98
ICPC
Health maint/preventive medicine
2.9
11.0
1222
11519
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.3
10.9
40
123
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
10.9
258
1698
F34.1
ICD-10 Finland
Dysthymia
2.9
10.8
50
176
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.3
10.8
86
395
R03BA05
ATC
fluticasone; inhalant
1.8
10.8
177
1052
A02BA02
ATC
ranitidine; systemic
1.8
10.7
171
1008
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
10.7
261
1729
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
60.5
10.6
12
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
10.6
367
2641
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.7
10.5
24
52
205
Kela drug reimbursment
Chronic hypertension
1.7
10.4
226
1451
Y55
ICPC
Male Genital, Local injection/infiltration
110.9
10.4
11
*
2572A
ICD-9 Finland
Testicular dysfunction, Other testicular hypofunction
+∞
10.4
10
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.9
10.4
138
767
J01DA01
ATC
[U] cefalexin
1.5
10.3
676
5535
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
3.0
10.3
46
159
Y29
ICPC
Genital symptom/complaint male other
4.5
10.3
25
57
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
4.8
10.3
23
49
L17
ICPC
Foot/toe symptom/complaint
1.6
10.2
259
1730
F32.1
ICD-10 Finland
Moderate depressive episode
2.4
10.2
73
321
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
10.1
116
613
A99
ICPC
Disease/condition unspecnature/site
2.1
10.1
94
460
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
10.0
866
7472
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
40.4
10.0
12
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.2
10.0
88
422
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
10.0
253
1690
M05BA04
ATC
alendronic acid; oral
3.1
10.0
40
130
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
10.0
160
944
R05
ICD-10 Finland
Cough
1.7
9.9
201
1267
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
9.9
295
2047
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
9.9
113
597
SCA01
NOMESCO Finland
Preventive oral health care, short
1.6
9.9
299
2082
R35
ICD-10 Finland
Polyuria
2.2
9.9
84
397
AA1AD
NOMESCO Finland
CT of head and brain
1.6
9.8
274
1873
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
10.7
9.8
18
17
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.3
9.8
71
314
N03AX09
ATC
lamotrigine; oral
2.4
9.7
68
296
P03
ICPC
Feeling depressed
2.1
9.7
97
489
SPAT1310
SPAT
Counselling related to known health issue
1.6
9.7
294
2049
OAB72
NOMESCO Finland
Weight control and weight loss guidance
7.9
9.6
21
27
C08CA01
ATC
amlodipine; oral
1.5
9.6
386
2857
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.1
9.6
40
133
R03AK08
ATC
formoterol and beclometasone; inhalant
2.8
9.6
48
177
R01AD01
ATC
beclometasone; nasal
1.8
9.6
166
1001
J01MA14
ATC
moxifloxacin; systemic
2.0
9.5
105
548
C07AB12
ATC
nebivolol; oral
2.8
9.5
46
167
M25.5
ICD-10 Finland
Pain in joint
1.5
9.4
338
2442
ZXD05
NOMESCO Finland
Urgent procedure
1.5
9.4
313
2224
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
9.4
9
*
75210
ICD-8 Finland
Congenital anomalies of genital organs, Undescended testicle
3.5
9.4
31
89
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
9.3
114
616
S76.4
ICD-10 Finland
Injury of other and unspecified muscles and tendons at thigh level
4.6
9.3
22
49
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
9.3
186
1168
R03AC03
ATC
terbutaline; inhalant
1.8
9.2
136
781
A02BC04
ATC
rabeprazole; oral
2.0
9.2
101
526
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
9.2
661
5462
SPAT1325
SPAT
Vaccination
1.6
9.1
262
1799
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.5
9.1
56
230
HMAK, ,
NOMESCO Finland
1.9
9.0
126
712
A04
ICPC
Weakness/tiredness general
1.9
9.0
114
624
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
8.9
77
366
Z3231
NOMESCO Finland
Registered nurse
1.5
8.9
284
1995
N04BC06
ATC
cabergoline; oral
24.2
8.9
12
5
M01AX05
ATC
glucosamine; oral
1.9
8.9
122
686
N06AG02
ATC
moclobemide; oral
2.6
8.8
51
203
F90.0
ICD-10 Finland
Disturbance of activity and attention
2.6
8.8
51
203
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
3.3
8.8
32
98
ZXA10
NOMESCO Finland
Bilateral
1.8
8.8
148
885
WX002
NOMESCO Finland
Sedation and analgesia
1.7
8.8
187
1193
UJF32
NOMESCO Finland
Coloscopy
1.6
8.8
250
1713
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
50.3
8.7
10
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
8.7
68
311
SPAT1263
SPAT
Sampling
1.5
8.7
405
3078
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
8.7
245
1675
G04BD12
ATC
mirabegron; oral
2.0
8.7
95
495
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.4
8.6
58
248
M01AH01
ATC
celecoxib; oral
1.7
8.6
164
1015
C62.12
ICD-10 Finland
Malignant tumor of the descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
11.7
8.6
15
13
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
3.8
8.5
25
66
SPAT1312
SPAT
General health counselling
1.5
8.5
292
2082
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.9
8.5
102
548
Z01.9
ICD-10 Finland
Special examination, unspecified
2.3
8.5
62
275
N02AA05
ATC
oxycodone; systemic
1.7
8.5
158
972
F32
ICD-10 Finland
Depressive episode
2.3
8.5
63
282
N06AA09
ATC
amitriptyline; systemic
2.1
8.4
79
388
WX722
NOMESCO Finland
PEEP
2.2
8.4
70
328
G03GA05
ATC
follitropin alfa; parenteral
90.6
8.4
9
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
90.6
8.4
9
*
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
90.6
8.4
9
*
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
90.6
8.4
9
*
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
8.4
163
1014
X58
ICD-10 Finland
Exposure to other specified factors
1.6
8.4
210
1394
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.8
8.4
40
144
A10BA02
ATC
metformin; oral
1.5
8.4
302
2176
M54.6
ICD-10 Finland
Pain in thoracic spine
2.0
8.3
86
438
E23.03
ICD-10 Finland
Lack of ACTH
+∞
8.3
8
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
8.3
97
516
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
8.3
232
1580
Y99
ICPC
Genital disease male other
8.6
8.3
17
20
C09CA01
ATC
losartan; oral
1.5
8.3
263
1843
L04AA06
ATC
mycophenolic acid; systemic
3.1
8.3
33
107
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
8.3
67
311
A06AD11
ATC
lactulose; oral
1.9
8.3
112
627
R4110, ,
SPAT
2.1
8.2
73
352
R01AD11
ATC
triamcinolone; nasal
2.0
8.1
88
456
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
8.1
126
735
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
8.1
541
4378
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.4
8.1
56
243
H05BX01
ATC
cinacalcet; oral
22.2
8.0
11
5
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.8
8.0
119
686
R03AC13
ATC
formoterol; inhalant
2.6
8.0
46
183
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
8.0
151
933
M01AB55
ATC
diclofenac, combinations; oral
2.4
8.0
54
232
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
7.9
256
1801
C08CA02
ATC
felodipine; oral
2.0
7.9
81
412
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
7.9
311
2279
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.5
7.9
47
190
M54
ICD-10 Finland
Dorsalgia
1.7
7.9
149
920
ZXA05
NOMESCO Finland
Left side
1.6
7.9
230
1582
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
7.8
132
789
E03
ICD-10 Finland
Other hypothyroidism
3.0
7.8
33
111
L03AA02
ATC
filgrastim; parenteral
2.8
7.8
37
133
M54.2
ICD-10 Finland
Cervicalgia
1.9
7.7
90
479
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
7.7
206
1387
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.6
7.7
184
1206
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.0
7.7
84
437
R03BA02
ATC
budesonide; inhalant
1.7
7.7
162
1029
J45
ICD-10 Finland
Asthma
1.9
7.7
95
516
C09DA03
ATC
valsartan and diuretics; oral
2.4
7.7
53
230
S18
ICPC
Laceration/cut
1.4
7.6
469
3728
T90
ICPC
Diabetes non-insulin dependent
1.5
7.6
257
1822
SPAT1301
SPAT
No procedures
1.5
7.6
272
1952
D11
ICPC
Diarrhoea
1.8
7.6
119
696
N03AE01
ATC
clonazepam; systemic
2.1
7.6
67
322
A07DA03
ATC
loperamide; oral
2.9
7.6
35
124
A69
ICPC
General and Unspecified, Other reason for encounter NEC
3.2
7.6
29
92
R99
ICPC
Respiratory disease other
3.3
7.5
27
82
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
7.5
89
476
R86.1
ICD-10 Finland
Abnormal findings in specimens from male genital organs, abnormal level of hormones
10.1
7.5
14
14
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
7.5
97
534
R06AE09
ATC
levocetirizine; oral
1.7
7.5
145
900
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.0
7.5
82
427
SAA04
NOMESCO Finland
Special examination of mouth
2.2
7.5
63
297
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
7.5
143
885
H02.3
ICD-10 Finland
Blepharochalasis
2.5
7.5
45
183
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.7
7.4
39
148
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
80.6
7.4
8
*
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
2.6
7.4
40
154
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
3.5
7.4
25
73
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.8
7.4
113
656
Z3226
NOMESCO Finland
Physiotherapist
1.6
7.4
170
1105
M01AC01
ATC
piroxicam; systemic, rectal
1.7
7.4
128
772
A02BA03
ATC
famotidine; systemic
2.9
7.4
33
115
L86
ICPC
Back syndrome with radiating pain
2.1
7.4
64
306
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.3
760
6577
OAB50, ,
SPAT
2.1
7.3
69
340
R06AX18
ATC
acrivastine; oral
3.1
7.3
29
94
G03GA06
ATC
follitropin beta; parenteral
+∞
7.3
7
*
Q53.9
ICD-10 Finland
Undescended testicle, unspecified
+∞
7.3
7
*
G03GA02
ATC
human menopausal gonadotrophin; parenteral
+∞
7.3
7
*
R21
ICPC
Throat symptom/complaint
1.6
7.3
183
1214
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
7.3
129
783
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
7.3
79
411
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.5
7.3
227
1583
J01MA01
ATC
ofloxacin; systemic
1.9
7.2
83
440
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.0
7.2
72
363
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
7.2
77
398
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.1
7.2
29
95
L01
ICPC
Neck symptom/complaint
1.7
7.2
131
801
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
7.2
176
1161
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
7.2
78
406
9061/3-C62.1
ICD-O-3
Seminoma, NOS, of descended testis
30.2
7.2
9
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.1
828
7286
321
Kela drug reimbursment
Paricalcitol and cinacalcet
20.1
7.1
10
5
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
20.1
7.1
10
5
196
Kela drug reimbursment
Paricalcitol and cinacalcet
20.1
7.1
10
5
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
7.1
47
200
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.6
7.1
174
1148
B01AB05
ATC
enoxaparin; parenteral
1.5
7.0
269
1954
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
3.7
7.0
22
61
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.3
7.0
53
239
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
7.0
127
775
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
7.0
7.0
16
23
7525A
ICD-9 Finland
Congenital anomalies of genital organs, Undescended testicle[RETENTIO TESTIS (CRYPTORCHISMUS)]
7.0
7.0
16
23
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
7.0
283
2079
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.4
7.0
24
71
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
3.0
7.0
29
97
R06AX13
ATC
loratadine; oral
1.7
6.9
142
895
-1, ,
ICPC
2.7
6.9
36
136
R42
ICD-10 Finland
Dizziness and giddiness
1.6
6.9
177
1181
R04.0
ICD-10 Finland
Epistaxis
2.0
6.9
75
391
D82
ICPC
Teeth/gum disease
1.4
6.9
403
3167
WX290
NOMESCO Finland
Other blockage of nerve
1.4
6.9
582
4857
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
2.2
6.8
57
268
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
3.4
6.8
24
72
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.0
6.8
29
98
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
6.8
96
544
A10BK01
ATC
dapagliflozin; oral
1.8
6.8
93
522
SPAT1281
SPAT
Other administrative function
2.0
6.8
76
399
J20
ICD-10 Finland
Acute bronchitis
1.8
6.8
94
530
R31
ICD-10 Finland
Unspecified haematuria
1.7
6.8
114
681
C07AG02
ATC
carvedilol; oral
2.2
6.7
55
257
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.7
369
2865
D07AC13
ATC
mometasone; topical
1.4
6.7
297
2218
H02AB07
ATC
prednisone; oral
1.7
6.7
116
699
R39.1
ICD-10 Finland
Other difficulties with micturition
2.4
6.7
45
193
K30
ICD-10 Finland
Functional dyspepsia
1.8
6.7
95
540
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
6.7
87
481
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.0
6.7
28
94
D01AE15
ATC
terbinafine; topical
1.8
6.7
91
511
V29.9
ICD-10 Finland
Motorcycle rider [any] injured in unspecified traffic accident
2.9
6.7
30
105
E000006, ,
ATC
2.3
6.7
49
219
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.7
6.7
20
54
ZXD00
NOMESCO Finland
Emergency procedure
2.8
6.6
33
122
R52.9
ICD-10 Finland
Pain, unspecified
1.8
6.6
98
564
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
12.3
6.6
11
9
L02
ICPC
Back symptom/complaint
1.8
6.6
95
543
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.0
6.6
66
334
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.0
6.6
28
95
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
6.6
289
2155
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.4
6.6
45
195
S04
ICPC
Lump/swelling localized
1.8
6.6
89
499
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
6.6
171
1144
NH3AA, ,
SPAT
2.1
6.5
61
300
R05FB02
ATC
cough suppressants and expectorants; systemic
1.4
6.5
316
2397
SPAT1255
SPAT
Intravenous administration of medicine
2.0
6.5
71
370
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.0
6.5
70
363
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
3.7
6.5
20
55
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.7
6.5
108
644
N06AX05
ATC
trazodone; oral
2.8
6.5
32
118
J02AC02
ATC
itraconazole; systemic
1.6
6.5
153
1000
ZX114, ,
SPAT
5.4
6.5
18
34
L29
ICPC
Musculoskeletal sympt/complt other
2.0
6.5
71
371
XA420
NOMESCO Finland
Extensive sleep examination
3.5
6.5
21
60
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
1.9
6.4
79
429
A07EA06
ATC
budesonide; oral, local oral
2.3
6.4
45
197
C62.19
ICD-10 Finland
Malignant tumor of the descending testicle, other or undetermined histology
14.4
6.4
10
7
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.3
6.4
46
204
ZX120
NOMESCO Finland
Intravenous
1.8
6.3
89
505
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
6.3
65
332
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.5
6.3
38
155
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
6.3
277
2064
SPAT1240
SPAT
Therapeutic discussion
1.7
6.3
104
619
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.3
102
604
E29.0
ICD-10 Finland
Testicular hyperfunction
+∞
6.3
6
*
301
Kela drug reimbursment
Growth hormone
+∞
6.3
6
*
F51
ICD-10 Finland
Nonorganic sleep disorders
2.2
6.2
48
219
K59.1
ICD-10 Finland
Functional diarrhoea
2.2
6.2
48
219
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
6.2
334
2578
M77.1
ICD-10 Finland
Lateral epicondylitis
1.7
6.2
109
660
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.8
6.2
91
523
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
6.2
44
194
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
3.5
6.2
20
57
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
3.5
6.2
20
57
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.5
6.1
37
151
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.9
6.1
76
415
KFB00
NOMESCO Finland
Biopsy of testis
12.6
6.1
10
8
R05FA02
ATC
opium derivatives and expectorants; systemic
1.4
6.1
355
2777
A10BJ06
ATC
semaglutide; parenteral
2.0
6.1
67
351
E000002, ,
ATC
1.7
6.1
99
587
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.5
6.1
35
140
TAB00
NOMESCO Finland
Lumbar puncture
2.1
6.1
52
248
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.1
6.1
52
248
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
1.9
6.0
71
380
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
6.0
104
626
XKC03
NOMESCO Finland
Water cystometry
3.2
6.0
23
73
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.2
6.0
23
73
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
6.0
102
611
D07AD01
ATC
clobetasol; topical
1.6
6.0
152
1009
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.0
695
6032
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.0
6.0
62
317
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
6.0
80
446

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
674
590
23.37
307.65
3.3
1.6
206.98
222.63
pmol/l
1.90
667
560
733
797
20.56
307.65
3.1
1.6
29.92
37.99
nmol/l
17.12
724
774
1075
1843
33.62
307.65
5.9
2.0
12.71
14.55
nmol/l
10.83
1032
1713
524
345
25.26
307.65
2.1
1.3
8.01
4.66
u/l
8.43
431
287
371
253
20.35
307.65
1.6
1.4
231.70
252.46
mu/l
0.60
348
238
219
125
20.99
276.20
2.0
1.3
15.11
7.78
iu/l
4.67
171
99
1099
6391
6.57
134.35
4.8
3.8
1.36
1.96
ug/l
9.12
1037
5859
95
44
23.27
129.44
1.9
1.6
0.12
0.13
nmol/l
0.15
76
33
316
765
5.18
125.86
2.2
2.0
355.15
370.70
nmol/l
0.85
299
709
161
253
7.15
100.18
1.7
1.3
175.01
213.98
pmol/l
0.51
161
253
92
83
11.88
88.29
1.7
1.3
—
—
—
0
0
868
5074
3.28
84.22
3.8
3.3
22.93
20.91
%
2.70
328
1962
62
36
18.06
76.05
1.4
1.2
20.13
7.89
u/l
3.59
51
28
981
6390
3.40
74.59
3.9
2.9
14.44
14.82
pmol/l
5.10
922
5853
618
3232
2.79
68.92
3.2
2.5
165.93
207.17
ug/l
3.18
583
3044
668
3754
2.66
62.79
3.0
2.5
0.63
0.67
ug/l
0.50
367
2097
62
68
9.54
51.64
6.2
4.9
4.42
32.24
u/l
0.79
19
11
67
86
8.17
49.30
1.4
1.2
—
—
—
0
0
1089
8376
3.19
46.63
4.9
3.5
1.80
2.04
mu/l
1.00
1040
7745
971
7292
2.44
39.01
8.5
7.9
71.38
77.37
u/l
8.48
937
6983
43
42
10.56
38.83
1.0
1.0
—
—
—
0
0
520
3111
2.14
36.36
2.7
2.1
76.10
71.62
nmol/l
3.09
480
2868
276
1359
2.32
30.48
3.2
2.5
15.73
14.35
umol/l
1.51
253
1286
261
1268
2.33
29.67
3.2
2.4
2.40
2.30
g/l
2.35
235
1191
687
4784
1.96
29.51
6.7
7.1
12.43
12.86
umol/l
0.29
663
4592
658
4554
1.93
28.38
8.1
7.1
—
—
—
0
0
248
1203
2.32
28.17
3.3
2.5
26.26
25.06
%
0.63
210
1064
171
700
2.67
27.99
4.3
3.4
—
—
—
0
0
770
5630
1.94
27.98
6.4
5.5
6.75
6.83
mmol/l
0.45
732
5362
1124
9523
2.65
26.77
6.4
5.1
40.04
39.82
mmol/mol
0.32
1071
9038
882
6822
1.97
26.28
4.4
3.7
8.19
9.35
mm/h
2.22
849
6411
1210
10697
4.18
26.17
5.8
4.5
2.71
2.87
mmol/l
8.85
1157
10108
153
614
2.70
25.97
5.7
3.9
1.21
1.22
mmol/l
0.67
137
557
419
2562
1.95
25.55
3.1
3.6
2.35
2.35
mmol/l
0.21
382
2319
566
3819
1.87
25.51
5.5
5.8
37.08
36.40
g/l
2.29
544
3604
1198
10595
3.58
24.40
5.4
4.2
4.44
4.66
mmol/l
11.89
1147
10065
651
4650
1.83
23.90
7.5
6.9
28.23
28.04
%
0.17
628
4436
1193
10549
3.39
23.81
5.4
4.1
1.16
1.28
mmol/l
32.30
1143
9985
549
3726
1.84
23.81
8.9
7.2
1.21
1.20
mmol/l
1.09
515
3460
1047
8729
2.17
23.73
20.0
15.6
14.97
14.98
%
0.00
1036
8576
591
4108
1.83
23.66
9.4
7.7
1.21
1.20
mmol/l
1.56
475
3579
631
4476
1.82
23.60
7.5
6.9
2.92
2.99
%
0.33
608
4262
634
4507
1.82
23.51
7.7
7.2
8.97
9.03
%
0.19
609
4292
608
4269
1.82
23.48
13.2
9.6
0.08
0.00
e9/l
0.51
549
3532
1175
10335
2.99
23.04
19.8
14.7
139.61
139.70
mmol/l
0.84
1159
10105
786
5985
1.83
22.99
4.2
3.5
—
—
—
0
0
615
4356
1.80
22.87
7.5
6.9
0.70
0.68
%
0.43
592
4149
485
3209
1.83
22.52
2.0
1.8
96.21
94.19
pmol/l
0.50
280
1868
1178
10399
3.00
22.47
20.0
14.7
4.03
4.01
mmol/l
2.78
1161
10166
699
5163
1.79
22.37
4.2
3.3
531.50
1228.28
e6/l
—
10
64
678
4971
1.79
22.18
7.5
7.0
0.20
0.20
e9/l
0.06
627
4423
636
4582
1.78
22.04
7.1
6.7
56.39
56.69
%
0.28
615
4370
1205
10793
3.58
21.98
17.9
11.5
—
—
—
0
0
142
598
2.55
21.76
2.0
1.6
—
—
—
0
0
660
4821
1.77
21.68
7.0
6.7
0.04
0.04
e9/l
0.18
607
4232
68
188
3.77
21.54
1.3
1.2
13.58
43.28
u/l
1.79
63
161
1231
11200
5.03
21.48
12.7
9.7
35.80
33.95
u/l
2.14
1206
10917
1155
10142
2.64
21.39
17.3
12.9
21.42
25.14
mg/l
3.89
974
7935
1164
10263
2.73
21.30
4.9
3.8
1.67
1.48
mmol/l
7.32
1114
9680
674
4973
1.76
21.20
7.1
6.7
1.96
1.95
e9/l
0.05
631
4450
657
4820
1.76
21.01
7.1
6.7
0.62
0.61
e9/l
0.50
605
4227
433
2820
1.82
20.82
3.0
2.6
5564.59
5091.03
umol/l
0.07
391
2570
531
3678
1.77
20.67
3.8
3.3
30.23
44.95
ng/l
1.42
375
2441
393
2492
1.84
20.58
3.2
2.6
—
—
—
0
0
375
2348
1.85
20.42
6.0
4.3
7.40
7.40
ph
0.28
122
455
72
216
3.47
20.21
4.1
4.3
2.29
2.12
mmol/l
0.27
50
135
72
216
3.47
20.21
4.1
4.3
9.02
8.70
kpa
0.62
72
210
72
217
3.46
20.07
4.1
4.3
4.97
5.03
kpa
0.31
72
211
467
3140
1.77
19.98
3.8
3.4
9.53
9.24
mmol/l
0.52
400
2716
884
7120
1.81
19.91
4.0
3.5
—
—
—
0
0
26
9
29.45
19.68
1.7
1.3
—
—
—
0
0
295
1729
1.92
19.63
3.2
2.7
560.24
592.30
mosm/kgh2o
1.51
264
1491
305
1808
1.91
19.60
3.0
2.4
2.27
2.73
e6/l
0.57
279
1628
595
4302
1.72
19.55
4.8
4.0
0.00
0.00
estimate
-0.00
162
806
599
4339
1.72
19.55
3.5
2.9
0.02
0.00
estimate
0.45
153
727
596
4322
1.72
19.29
3.5
2.9
0.00
0.00
estimate
0.80
162
820
716
5460
1.72
19.25
9.5
10.5
4.36
4.16
e9/l
0.42
653
4791
414
2713
1.78
19.18
3.8
3.1
103.80
161.59
e6/l
0.39
337
2103
290
1705
1.91
19.05
1.7
1.5
18.95
19.37
nmol/l
0.20
257
1503
93
342
2.86
18.54
2.9
2.9
1.42
1.41
mg/l
0.03
87
326
1114
9768
2.20
18.30
5.0
4.0
6.07
6.04
mmol/l
0.25
1045
9099
503
3519
1.71
18.28
3.5
3.7
33.55
40.69
u/l
0.90
476
3332
226
1237
2.01
18.23
8.8
7.2
1.02
1.02
mmol/l
0.01
218
1185
383
2488
1.77
18.08
4.1
3.6
—
—
—
0
0
302
1827
1.86
18.04
2.4
2.1
3.15
2.89
mg/l
0.94
257
1593
394
2587
1.76
17.89
1.8
1.7
1.82
1.59
mmol/l
2.44
329
2215
380
2471
1.77
17.84
3.8
3.0
0.38
0.42
e6/l
0.13
308
1878
417
2798
1.73
17.46
3.6
3.3
209.00
239.11
mg/l
0.07
298
1949
76
260
3.05
17.24
4.2
4.4
7.42
7.41
ph
0.39
76
228
584
4303
1.66
17.12
13.3
12.5
1.19
1.24
inr
1.04
232
1243
434
2957
1.71
17.12
2.6
2.8
55.60
61.45
u/l
1.47
405
2801
300
1838
1.83
17.10
1.3
1.2
2.71
1.92
u/ml
0.24
91
530
134
613
2.33
17.03
7.6
10.2
24.84
24.88
mmol/l
0.04
134
606
24
11
22.21
16.89
1.4
1.2
—
—
—
0
0
372
2449
1.74
16.50
3.8
2.9
—
—
—
0
0
500
3564
1.67
16.49
3.0
2.7
5.75
5.73
ph
0.05
50
422
949
7984
1.76
16.38
3.7
3.3
56.99
56.24
u/l
0.10
908
7624
198
1073
2.00
16.31
1.4
1.4
—
—
—
0
0
429
2947
1.69
16.23
4.3
3.9
9.87
8.86
mg/mmol
0.20
302
2028
412
2801
1.70
16.20
2.6
2.3
279.36
379.32
u/l
0.83
391
2660
620
4693
1.63
15.95
3.4
2.6
—
—
—
0
0
64
212
3.13
15.34
4.1
3.7
—
—
—
0
0
272
1673
1.80
15.09
1.7
1.6
69658538.70
29841900.27
pmol/l
0.34
234
1451
115
520
2.33
14.98
2.1
2.5
—
—
—
0
0
380
2575
1.68
14.89
5.1
4.6
—
—
—
0
0
294
1858
1.76
14.85
2.3
1.8
—
—
—
0
0
432
3031
1.65
14.77
4.3
3.5
92.42
63.60
e6/l
0.32
350
2235
285
1788
1.77
14.75
1.7
1.5
2.38
2.69
g/l
2.38
205
1236
92
380
2.53
14.61
3.1
3.7
4.75
4.68
pmol/l
0.30
86
349
242
1458
1.82
14.32
3.3
2.8
—
—
—
0
0
21
11
19.39
14.25
1.3
1.5
1.57
1.48
%
0.30
21
11
91
380
2.50
14.12
1.1
1.2
76.66
131.10
iu/ml
1.06
30
125
322
2124
1.69
13.81
2.1
1.8
0.91
1.12
mg/l
0.68
240
1565
132
661
2.11
13.39
2.0
3.1
68.32
67.15
g/l
1.27
123
621
333
2232
1.67
13.38
3.8
3.3
0.01
0.01
estimate
0.07
153
741
1244
11749
5.12
13.24
27.2
18.5
43.96
43.02
%
1.42
1206
11121
102
464
2.30
13.10
4.9
4.4
108.68
87.72
ng/l
0.71
88
423
1244
11759
5.06
13.01
26.9
18.2
232.49
239.07
e9/l
3.65
1231
11505
57
195
3.01
12.96
2.8
2.6
18.21
17.20
%
0.63
31
104
1244
11765
5.02
12.87
26.7
18.1
30.38
30.50
pg
1.87
1239
11633
1244
11768
5.00
12.80
26.8
18.1
90.35
90.47
fl
0.44
1239
11636
1244
11770
4.99
12.76
26.9
18.2
4.94
4.78
e12/l
18.24
1229
11495
1244
11772
4.98
12.71
26.9
18.2
6.85
6.66
e9/l
0.50
1228
11500
1244
11772
4.98
12.71
27.1
18.3
149.35
145.00
g/l
15.99
1239
11634
56
192
3.01
12.69
3.8
4.0
55.32
55.60
%
0.06
56
192
147
781
2.00
12.69
5.1
4.8
1.75
0.89
%
1.83
51
279
141
740
2.02
12.59
5.2
4.9
0.16
0.13
%
0.17
43
238
135
699
2.04
12.51
5.0
4.8
0.17
0.11
%
0.22
36
193
434
3164
1.57
12.12
2.0
1.9
—
—
—
0
0
54
187
2.97
12.03
3.0
3.7
3.41
3.93
e9/l
1.53
54
187
136
718
2.00
11.93
4.9
4.5
1.27
0.61
%
0.74
44
243
193
1146
1.81
11.83
2.6
2.8
135.94
169.81
ug/g
0.65
174
987
337
2336
1.60
11.59
3.2
3.0
801.92
1176.59
ng/l
1.60
259
1940
118
605
2.05
11.22
3.3
3.2
7.40
7.41
ph
0.13
27
74
206
1275
1.74
10.91
1.8
1.7
1263.84
1154.69
nmol/l
0.95
149
1007
242
1572
1.67
10.71
5.0
4.3
0.83
0.82
mmol/l
0.87
234
1503
147
832
1.87
10.48
2.9
2.4
9.89
10.75
g/l
1.79
126
759
119
628
1.99
10.44
2.1
1.9
—
—
—
0
0
103
517
2.08
10.37
1.2
1.3
—
—
—
0
0
40
128
3.19
10.22
5.4
3.2
—
—
—
0
0
98
492
2.08
9.86
1.5
1.5
—
—
—
0
0
197
1246
1.69
9.58
1.4
1.3
246.40
361.35
titre
1.31
25
208
205
1312
1.67
9.53
2.6
3.6
2.43
2.43
mmol/l
0.04
189
1160
163
987
1.75
9.27
1.4
1.3
—
—
—
0
0
189
1200
1.68
9.04
1.3
1.2
—
—
—
0
0
207
1348
1.64
8.97
1.3
1.2
21.93
27.75
iu/ml
0.38
56
410
212
1396
1.62
8.77
1.9
1.5
—
—
—
0
0
32
99
3.29
8.66
3.8
2.4
—
—
—
0
0
213
1411
1.61
8.59
2.1
1.7
—
—
—
0
0
507
4026
1.43
8.55
2.8
2.6
—
—
—
0
0
120
679
1.85
8.55
3.6
2.9
79.12
70.92
e9/l
1.01
90
517
150
911
1.73
8.43
3.4
2.8
1.84
1.76
%
0.25
132
833
12
7
17.29
8.08
1.3
1.0
100.33
97.29
nmol/24h
—
12
7
356
2689
1.45
7.70
2.5
2.6
—
—
—
0
0
46
190
2.47
7.40
2.5
2.3
144.30
134.96
g/l
1.10
37
138
42
166
2.58
7.40
3.2
2.6
—
—
—
0
0
118
696
1.77
7.34
1.2
1.1
—
—
—
0
0
19
47
4.09
7.09
1.1
1.2
—
—
—
0
0
71
362
2.02
6.91
2.3
2.2
—
—
—
0
0
332
2520
1.43
6.88
4.6
4.6
89.36
88.94
%
0.12
324
2477
182
1224
1.57
6.83
1.3
1.2
1.45
9.04
u/ml
4.81
77
537
99
567
1.81
6.80
1.3
1.3
115.56
323.62
u/ml
3.02
93
523
203
1405
1.53
6.69
2.3
2.3
—
—
—
0
0
171
1159
1.55
6.18
2.1
1.8
—
—
—
0
0
137
883
1.62
6.14
5.5
4.3
1.88
1.94
mmol/l
0.06
118
731
28
99
2.87
6.12
3.2
2.6
33.61
33.71
pg
0.05
28
99
31
116
2.71
6.11
1.3
1.2
—
—
—
0
0
51
244
2.14
5.90
1.3
1.5
347.85
259.85
ug/g
2.65
34
139
17
45
3.82
5.82
3.9
7.4
86.70
68.61
mg/l
—
10
36
101
615
1.70
5.64
2.4
2.4
18.52
19.34
au/ml
—
5
61
80
456
1.81
5.62
3.2
3.1
—
—
—
0
0
44
203
2.21
5.58
1.5
1.7
0.62
1.02
g/l
1.58
24
152
135
888
1.58
5.56
5.3
4.2
5.96
5.88
kpa
0.43
128
863
300
2313
1.39
5.54
7.4
7.9
—
—
—
0
0
30
117
2.60
5.49
1.3
1.2
0.37
0.40
g/l
0.09
11
78
30
117
2.60
5.49
1.3
1.2
6.80
7.26
g/l
0.13
11
80
106
659
1.66
5.48
2.2
1.8
1.07
1.25
g/l
0.92
100
615
30
118
2.58
5.40
1.3
1.2
2.90
3.23
g/l
0.26
11
81
12
18
6.72
5.26
1.5
1.2
—
—
—
0
0
14
26
5.43
5.23
2.1
1.9
49.57
48.40
ug/l
0.03
14
26
147
1004
1.53
5.13
1.5
1.3
—
—
—
0
0
31
128
2.46
5.07
2.6
2.5
35.44
35.32
%
0.02
31
128
19
60
3.20
5.05
1.1
1.2
—
—
—
0
0
22
76
2.93
5.05
1.3
1.1
—
—
—
0
0
17
50
3.43
5.03
2.5
2.1
—
—
—
0
0
45
223
2.06
4.81
1.2
1.5
5.11
29.20
e6/l
0.90
36
162
45
223
2.06
4.81
1.3
1.5
184.85
1257.35
e6/l
0.73
39
171
162
1151
1.47
4.67
3.3
3.3
8.40
9.43
umol/l
0.24
149
1034
137
942
1.51
4.64
1.8
1.6
—
—
—
0
0
127
861
1.53
4.60
11.6
11.7
—
—
—
0
0
103
668
1.59
4.53
1.2
1.2
—
—
—
0
0
67
389
1.76
4.48
1.2
1.2
—
—
—
0
0
197
1464
1.41
4.46
3.4
2.9
0.46
0.50
e6/l
0.10
109
800
48
251
1.95
4.44
1.1
1.1
0.83
5.61
u/ml
—
6
32
269
2108
1.35
4.40
2.5
2.5
—
—
—
0
0
182
1338
1.42
4.38
1.6
1.4
—
—
—
0
0
132
913
1.50
4.35
2.5
2.5
0.23
0.22
g/l
0.44
125
846
41
206
2.02
4.25
1.3
1.5
—
—
—
0
0
97
634
1.57
4.15
2.6
3.2
4.50
5.97
e9/l
0.76
87
544
23
91
2.56
4.14
2.5
2.6
1.64
2.24
g/24h
0.26
14
50
78
486
1.64
4.06
6.8
4.2
24.08
24.31
mmol/l
0.23
78
479
15
48
3.15
3.93
2.4
1.6
—
—
—
0
0
33
158
2.12
3.90
2.8
1.7
—
—
—
0
0
31
145
2.17
3.89
1.1
1.1
2.17
2.19
u/ml
0.01
14
75
203
1551
1.37
3.88
3.4
2.7
0.49
0.87
e6/l
2.16
115
881
45
243
1.88
3.83
3.8
3.6
36.94
37.39
mg/l
0.02
30
191
18
67
2.71
3.66
2.3
2.3
506.45
501.58
min
0.05
11
48
44
243
1.84
3.52
3.8
3.6
70.06
88.90
mg/l
0.22
29
190
95
648
1.50
3.39
1.3
1.4
—
—
—
0
0
19
76
2.52
3.39
1.5
2.7
—
—
—
0
0
151
1130
1.38
3.29
10.3
10.4
0.88
0.99
mmol/l
0.12
133
902
87
589
1.51
3.23
4.4
3.8
135.28
135.40
g/l
0.01
82
577
35
185
1.92
3.22
4.2
3.5
—
—
—
0
0
32
164
1.98
3.21
1.3
1.3
—
—
—
0
0
25
117
2.16
3.17
1.6
1.4
—
—
—
0
0
63
398
1.61
3.16
1.5
1.8
1.48
1.54
g/l
0.20
54
341
39
216
1.83
3.12
1.2
1.1
—
—
—
0
0
44
254
1.76
3.08
1.8
1.6
—
—
—
0
0
47
277
1.72
3.07
3.2
4.0
—
—
—
0
0
34
183
1.88
2.98
1.1
1.1
1.67
1.57
u/ml
0.02
15
71
5
5
10.03
2.98
2.8
2.8
—
—
—
0
0
11
32
3.46
2.90
1.1
1.1
—
—
—
0
0
20
89
2.27
2.87
1.1
1.1
—
—
—
0
0
102
734
1.42
2.81
5.2
4.3
—
—
—
0
0
229
1866
1.28
2.77
3.4
3.7
717.86
643.95
ng/l
0.06
175
1438
76
521
1.49
2.70
2.5
2.9
—
—
—
0
0
52
327
1.62
2.70
3.4
4.0
0.34
0.32
g/l
0.03
29
190
38
220
1.75
2.67
1.1
1.1
313.33
84.85
iu/ml
—
6
60
34
191
1.80
2.64
1.1
1.1
2.89
7.56
u/ml
1.65
19
96
155
1210
1.32
2.59
1.4
1.4
—
—
—
0
0
125
947
1.36
2.56
1.6
1.4
—
—
—
0
0
6
11
5.47
2.54
3.7
2.6
164.77
154.82
ng/l
—
6
11
21
102
2.08
2.48
5.2
5.0
—
—
—
0
0
21
102
2.08
2.48
3.3
2.4
13.22
11.57
%
0.74
21
102
93
677
1.40
2.43
2.5
2.6
—
—
—
0
0
40
243
1.67
2.40
1.8
1.6
109.67
117.78
u/ml
0.16
12
44
15
64
2.36
2.39
3.1
3.0
678.33
1191.61
u/ml
0.70
15
64
94
688
1.40
2.39
1.4
1.4
—
—
—
0
0
18
84
2.16
2.35
2.0
1.5
80.00
84.88
umol/l
0.65
18
84
54
356
1.54
2.33
1.2
1.1
—
—
—
0
0
91
668
1.39
2.28
2.5
2.6
—
—
—
0
0
45
286
1.59
2.28
2.4
2.2
311.14
140.17
ug/min
0.43
29
174
43
271
1.61
2.25
1.3
1.2
291.67
269.82
u/ml
0.19
24
170
90
661
1.39
2.25
2.6
2.6
—
—
—
0
0
40
249
1.63
2.21
2.0
3.0
—
—
—
0
0
91
676
1.37
2.14
2.5
2.3
—
—
—
0
0
62
430
1.46
2.13
4.4
3.8
—
—
—
0
0
37
228
1.64
2.13
1.2
1.1
—
—
—
0
0
18
88
2.06
2.12
2.2
2.3
868.73
634.70
ml
1.06
11
56
85
626
1.38
2.11
2.6
2.7
—
—
—
0
0
30
176
1.72
2.07
1.1
1.2
—
3.08
—
0
12
61
425
1.46
2.06
3.9
4.1
25.69
24.98
mmol/l
0.83
54
411
37
231
1.62
2.04
5.0
3.5
—
—
—
0
0
41
264
1.57
2.00
1.2
1.9
1.09
0.87
nmol/l
1.13
34
235
15
70
2.16
1.98
1.1
1.2
—
—
—
0
0
20
105
1.92
1.96
1.3
1.6
52.30
62.24
%
—
10
71
52
355
1.48
1.95
1.3
1.2
—
—
—
0
0
34
211
1.63
1.93
1.2
1.1
3.36
1.85
u/ml
0.23
19
101
7
22
3.19
1.88
1.1
1.0
—
—
—
0
0
25
144
1.75
1.86
3.0
3.0
—
—
—
0
0
89
677
1.34
1.83
13.1
13.0
0.58
0.68
%
1.52
89
671
18
94
1.93
1.80
3.1
3.1
39.00
39.44
%
0.03
11
42
89
679
1.33
1.80
13.1
12.8
1.41
1.48
%
0.20
89
674
23
131
1.77
1.78
3.4
2.7
—
—
—
0
0
222
1900
1.20
1.72
3.6
3.0
—
—
—
0
0
11
48
2.30
1.70
1.2
1.1
—
—
—
0
0
304
2679
1.18
1.70
1.5
1.3
—
—
—
0
0
12
55
2.19
1.67
1.1
1.1
162.12
264.92
iu/ml
0.78
12
55
8
31
2.59
1.66
1.3
1.4
—
—
—
0
0
8
31
2.59
1.66
4.1
2.8
—
—
—
0
0
16
83
1.94
1.65
1.2
1.3
—
—
—
0
0
219
1885
1.20
1.60
3.5
3.1
1.02
1.02
kg/l
0.66
22
234
76
582
1.33
1.53
14.1
14.0
—
—
—
0
0
38
258
1.49
1.52
1.2
1.1
—
—
—
0
0
116
941
1.26
1.51
2.8
2.9
31.06
92.89
u/l
0.70
104
852
24
146
1.66
1.51
1.2
1.2
—
—
—
0
0
51
367
1.41
1.51
3.0
2.6
—
—
—
0
0
11
51
2.17
1.50
1.0
1.2
—
71.40
%
—
0
5
6
21
2.87
1.50
1.2
2.4
—
—
—
0
0
12
58
2.08
1.49
1.4
1.2
161.33
149.83
nmol/l
0.33
12
58
28
180
1.57
1.43
1.1
1.1
3.46
2.47
u/ml
0.12
13
82
81
633
1.30
1.43
7.5
5.9
—
—
—
0
0
9
40
2.26
1.40
1.0
1.2
—
—
—
0
0
42
297
1.43
1.39
1.1
1.1
—
—
—
0
0
18
104
1.74
1.37
1.6
1.7
—
—
—
0
0
9
41
2.20
1.37
1.2
1.7
—
3.50
%
—
0
8
23
143
1.62
1.35
1.3
1.4
1.44
1.56
promille
0.12
13
112
25
159
1.58
1.35
1.7
1.8
—
—
—
0
0
146
1232
1.21
1.34
1.7
1.6
—
—
—
0
0
21
128
1.65
1.33
1.2
1.1
—
—
—
0
0
46
334
1.39
1.32
3.4
3.1
—
—
—
0
0
23
144
1.61
1.32
1.2
1.4
—
—
—
0
0
84
672
1.27
1.26
3.0
2.8
185.62
158.24
ng/l
0.20
75
593
24
154
1.57
1.26
1.3
1.6
—
—
—
0
0
88
709
1.26
1.25
3.0
3.1
—
—
—
0
0
7
142
0.49
1.21
24.1
14.6
827.86
821.20
nmol/l
—
7
137
38
273
1.40
1.18
1.3
1.2
—
—
—
0
0
5
20
2.51
1.15
2.4
2.0
—
—
—
0
0
59
460
1.30
1.11
2.6
2.4
—
—
—
0
0
53
408
1.31
1.09
7.6
5.1
—
—
—
0
0
23
152
1.52
1.09
1.0
1.1
4.30
3.11
u/ml
—
10
67
10
52
1.93
1.06
1.8
1.7
—
—
—
0
0
14
82
1.72
1.05
2.4
2.6
33112.21
43225.61
ug/l
1.88
14
82
24
162
1.49
1.04
1.0
1.1
0.34
3.10
u/ml
—
10
81
23
155
1.49
1.01
1.3
1.8
2.47
5.41
iu/l
—
7
54
45
343
1.32
1.01
1.8
1.7
—
—
—
0
0
13
76
1.72
0.99
1.9
3.0
—
—
—
0
0
9
49
1.84
0.98
1.0
1.0
—
—
—
0
0
21
140
1.51
0.98
1.0
1.1
0.08
0.69
u/ml
—
5
42
41
310
1.33
0.97
1.7
1.5
—
—
—
0
0
20
132
1.52
0.97
1.3
1.2
—
—
—
0
0
20
132
1.52
0.97
2.5
2.3
—
—
—
0
0
15
92
1.64
0.97
2.4
3.0
—
—
—
0
0
33
242
1.37
0.95
1.2
1.1
—
—
—
0
0
33
242
1.37
0.95
1.2
1.1
—
—
—
0
0
7
37
1.90
0.94
2.3
2.6
—
—
—
0
0
23
158
1.46
0.94
2.7
2.1
—
—
—
0
0
15
93
1.62
0.94
1.3
1.3
—
—
—
0
0
8
42
1.91
0.88
1.3
1.7
—
—
—
0
0
6
30
2.00
0.87
29.5
12.3
—
—
—
0
0
8
46
1.74
0.82
2.6
2.9
14.71
551.34
ug/l
—
8
40
6
32
1.88
0.82
1.0
1.3
—
—
—
0
0
26
189
1.38
0.81
2.8
2.5
640.00
1350.00
titre
—
5
16
0
24
0.00
0.79
0.0
3.8
—
4099.54
—
0
24
9
53
1.70
0.75
2.8
1.2
11.21
8.14
ug/l
—
9
48
39
307
1.28
0.74
8.6
7.5
1.40
1.34
mmol/l
0.20
32
266
14
92
1.53
0.72
1.3
1.5
44.00
28.69
%
—
5
64
18
126
1.43
0.70
1.3
1.4
—
—
—
0
0
9
59
1.53
0.68
9.0
4.4
—
—
—
0
0
7
118
0.59
0.68
3.4
2.5
—
—
—
0
0
11
70
1.58
0.65
1.4
1.7
—
—
—
0
0
10
62
1.62
0.65
2.1
3.2
—
—
—
0
0
5
29
1.73
0.64
1.0
1.2
—
—
—
0
0
5
30
1.67
0.61
13.0
7.7
—
—
—
0
0
5
30
1.67
0.61
1.8
1.3
—
—
—
0
0
62
528
1.18
0.60
1.2
1.3
—
—
—
0
0
12
80
1.50
0.60
1.3
1.3
—
—
—
0
0
12
80
1.50
0.60
1.3
1.1
—
—
—
0
0
8
52
1.54
0.59
1.8
1.2
—
—
—
0
0
14
97
1.45
0.59
1.4
4.1
—
—
—
0
0
8
55
1.46
0.56
1.3
1.1
—
—
—
0
0
6
37
1.62
0.55
1.3
1.1
178.42
205.76
mmol/24h
—
6
37
47
394
1.20
0.55
3.0
2.3
21.19
21.54
s
0.24
37
345
39
321
1.22
0.55
1.3
1.2
—
—
—
0
0
6
39
1.54
0.53
1.3
1.3
—
—
—
0
0
39
324
1.21
0.51
1.6
1.7
—
—
—
0
0
5
32
1.56
0.42
2.0
2.2
—
—
—
0
0
30
250
1.20
0.40
1.4
1.2
123.64
177.83
miu/ml
0.41
11
98
17
132
1.29
0.40
1.2
1.1
—
—
—
0
0
42
362
1.17
0.40
7.1
4.6
1.27
1.36
mmol/l
0.35
42
356
22
179
1.23
0.37
3.4
3.4
1.36
1.69
mmol/l
1.49
22
174
27
225
1.20
0.37
1.3
1.6
17868.05
19200.92
e6/l
0.05
19
167
9
69
1.31
0.37
1.8
1.4
—
—
—
0
0
16
126
1.27
0.35
1.4
1.3
75.18
64.22
mmol/l
0.35
11
103
6
43
1.40
0.35
2.0
2.5
—
—
—
0
0
13
100
1.30
0.33
1.2
1.1
—
—
—
0
0
10
74
1.35
0.32
1.4
1.6
—
—
—
0
0
6
47
1.28
0.32
1.5
1.5
—
—
—
0
0
12
93
1.29
0.30
1.3
1.0
—
—
—
0
0
187
1778
1.06
0.30
1.3
1.4
—
—
—
0
0
21
176
1.20
0.29
4.5
3.7
—
—
—
0
0
8
63
1.27
0.27
1.0
1.0
—
—
—
0
0
22
187
1.18
0.26
4.8
2.9
16.88
26.03
mg/l
0.72
17
119
8
67
1.20
0.26
1.6
1.4
—
—
—
0
0
9
72
1.25
0.25
1.0
1.7
—
—
—
0
0
11
87
1.27
0.24
1.3
1.2
—
—
—
0
0
7
93
0.75
0.22
1.0
1.2
11917.00
55302.87
e6/l
—
7
71
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.36
—
0
11
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
5
43
1.16
0.21
1.4
1.2
1366.80
1389.30
miu/ml
—
5
43
23
202
1.14
0.20
1.1
1.1
1.38
1.47
g/l
0.88
23
181
6
50
1.20
0.19
9.3
6.5
—
—
—
0
0
6
51
1.18
0.19
1.3
3.0
—
—
—
0
0
9
78
1.15
0.15
1.3
1.1
—
—
—
0
0
87
900
0.96
0.10
2.7
2.2
9.90
10.05
ug/l
0.02
77
823
5
46
1.09
0.09
2.0
1.2
—
—
—
0
0
6
55
1.09
0.09
1.2
1.1
—
—
—
0
0
6
56
1.07
0.08
1.0
1.3
—
3.17
—
0
6
6
56
1.07
0.08
1.0
1.0
—
—
—
0
0
30
315
0.95
0.06
17.3
9.7
—
—
—
0
0
10
90
1.11
0.05
1.5
1.3
1.27
1.46
g/l
—
10
90
11
102
1.08
0.03
1.5
1.4
0.92
1.05
g/l
0.54
11
102
74
751
0.98
0.02
4.7
5.1
20.39
25.73
ug/l
0.12
66
632
16
167
0.96
0.01
1.3
1.4
—
—
—
0
0
18
182
0.99
0.00
1.8
1.2
1.67
4.54
u/ml
—
9
90
36
358
1.01
0.00
1.1
1.1
—
—
—
0
0
10
99
1.01
0.00
1.8
3.0
—
—
—
0
0
10
99
1.01
0.00
3.6
6.0
—
—
—
0
0
18
175
1.03
0.00
1.1
1.2
—
—
—
0
0
5
57
0.88
0.00
1.2
1.4
—
—
—
0
0
7
70
1.00
-0.00
1.7
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
-0.00
1.3
1.5
8.23
6.33
mmol/l
—
7
71
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1696.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
89
1.01
-0.00
1.6
1.6
31.19
33.16
g/l
—
9
78
0
7
0.00
-0.00
0.0
5.3
—
511.86
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
41.50
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
35.26
—
0
5
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
1.08
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_TESTICHYPO and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
E4_TESTICHYPO 1.58 [1.3, 1.91] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 243 out of 2410 males with E4_TESTICHYPO died.

Mortality risk

Mortality risk for people of age

years, who have E4_TESTICHYPO.

N-year risk Females Males
1 No data 0.265%
5 No data 1.557%
10 No data 4.102%
15 No data 7.786%
20 No data 13.192%

Relationships between endpoints

Index endpoint: E4_TESTICHYPO – Testicular hypofunction

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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