Precocious central puberty

E4_PRECOXCENTPUB

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E22.80, E22.88
  • Hospital discharge: ICD-9 259
  • Cause of death: ICD-10 E22.80, E22.88
  • Cause of death: ICD-9 259

2 out of 7 registries used, show all original rules.

239

4. Check minimum number of events

None

239

5. Include endpoints

None

239

6. Filter based on genotype QC (FinnGen only)

239

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2852 1930 912
Only index persons 2430 1642 788
Unadjusted period prevalence (%)
Whole population 0.05 0.06 0.03
Only index persons 0.05 0.06 0.03
Median age at first event (years)
Whole population 9.59 8.54 11.31
Only index persons 9.31 8.52 10.97

-FinnGen-

Key figures

All Female Male
Number of individuals 239 165 74
Unadjusted period prevalence (%) 0.05 0.06 0.03
Median age at first event (years) 10.10 8.90 12.76

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
223
Matched controls
2228
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E22.80
ICD-10 Finland
Central precocious puberty
+∞
102.1
90
*
L02AE02
ATC
leuprorelin; implant, parenteral
62.3
52.4
60
13
2594A
ICD-9 Finland
Other endocrine disorders, Dwarfism, not elsewhere classified
+∞
46.5
43
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
36.5
34
*
H01AC01
ATC
somatropin; parenteral
+∞
33.1
31
*
E30.1
ICD-10 Finland
Precocious puberty
+∞
32.0
30
*
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
+∞
32.0
30
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
21.5
27.8
41
23
2591A
ICD-9 Finland
Other endocrine disorders, Precocious sexual development and puberty, not elsewhere classified
+∞
20.1
19
*
2590A
ICD-9 Finland
Other endocrine disorders, Delay in sexual development and puberty, not elsewhere classified
+∞
20.1
19
*
E22.88
ICD-10 Finland
Other hyperfunction of pituitary gland
+∞
20.1
19
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
15.8
15
*
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
15.8
15
*
L02AE04
ATC
triptorelin; parenteral
+∞
14.7
14
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
160.0
14.6
15
*
H02AB09
ATC
hydrocortisone; systemic
11.1
12.8
24
24
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
74.2
12.7
14
*
2592A
ICD-9 Finland
Other endocrine disorders, Carcinoid syndrome
+∞
12.6
12
*
2599X
ICD-9 Finland
Other endocrine disorders, Unspecified endocrine disorder
+∞
12.6
12
*
E22.1
ICD-10 Finland
Hyperprolactinaemia
+∞
11.6
11
*
102
Kela drug reimbursment
Diabetes insipidus
+∞
10.5
10
*
E34.35
ICD-10 Finland
Abnormal growth retardation
+∞
10.5
10
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.7
10.3
35
84
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
57.5
9.7
11
*
E34.31
ICD-10 Finland
Short stature, prenatal disorder
+∞
9.4
9
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.2
8.4
32
86
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
+∞
8.4
8
*
2598X
ICD-9 Finland
Other endocrine disorders, Other specified endocrine disorders
+∞
8.4
8
*
7834C
ICD-9 Finland
Symptoms concerning nutrition, metabolism and development, Lack of expected normal physiological development[HÄIRIINTYNYT PITUUSKASVU]
34.7
8.1
10
*
F82
ICD-10 Finland
Specific developmental disorder of motor function
11.4
7.9
14
13
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
7.1
7.8
18
27
H03AA01
ATC
levothyroxine sodium; systemic
3.0
7.7
46
175
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
7.6
67
322
H47.2
ICD-10 Finland
Optic atrophy
26.0
7.6
10
*
E34.30
ICD-10 Finland
Short stature NOS
+∞
7.3
7
*
E22.8
ICD-10 Finland
Other hyperfunction of pituitary gland
+∞
7.3
7
*
G81.1
ICD-10 Finland
Spastic hemiplegia
+∞
7.3
7
*
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
+∞
7.3
7
*
301
Kela drug reimbursment
Growth hormone
+∞
7.3
7
*
E30.8
ICD-10 Finland
Other disorders of puberty
+∞
7.3
7
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.4
7.2
15
19
L04AA01
ATC
[U] ciclosporin; systemic
31.1
7.2
9
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
6.9
39
144
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.8
6.9
22
50
602
Kela drug reimbursment
Children's severe malnutrition
23.3
6.7
9
*
E34.45
ICD-10 Finland
Abnormal growth increase
+∞
6.3
6
*
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
+∞
6.3
6
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
6.1
42
176

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3009214) Lutropin [Units/volume] in Serum or Plasma
51
101
6.15
25.82
3.6
1.4
u/l
6.5
7.8
0.45
46
78
(3023323) Follitropin [Units/volume] in Serum or Plasma
46
111
4.89
18.41
3.6
1.4
iu/l
9.4
13.3
0.62
39
83
(3035637) Corticotropin [Mass/volume] in Plasma
17
26
6.96
10.78
2.8
1.5
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
104
606
2.27
8.58
9.7
6.6
mmol/l
1.2
1.2
0.17
92
564
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
110
689
2.11
7.27
11.2
6.7
mmol/l
1.2
1.2
0.33
96
601
(3023368) Bacteria identified in Blood by Culture
59
287
2.40
7.24
5.6
4.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
78
446
2.11
6.40
5.2
4.5
inr
1.1
1.1
0.78
27
150
(3018418) pH of Serum or Plasma
65
363
2.09
5.59
5.2
3.2
ph
7.4
7.4
0.84
12
63
(3023103) Potassium [Moles/volume] in Serum or Plasma
209
1762
2.48
5.36
17.6
8.9
mmol/l
3.9
3.9
0.06
202
1691
(3019550) Sodium [Moles/volume] in Serum or Plasma
209
1762
2.48
5.36
17.9
8.9
mmol/l
139.6
139.5
0.28
202
1702
(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma
5
0
+∞
5.22
2.0
0.0
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
34
149
2.49
5.16
7.8
9.1
mmol/l
25.2
25.0
0.20
34
149
(3042936) Bacteria identified in Isolate by Culture
38
179
2.34
4.93
2.5
2.0
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
129
946
1.79
4.66
6.4
4.3
mmol/l
6.1
6.3
0.36
120
832
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
104
722
1.78
4.48
7.0
5.1
umol/l
9.6
10.2
0.35
98
669
(42870588) Differential panel, method unspecified - Blood
92
620
1.79
4.36
10.1
6.4
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
80
517
1.82
4.36
5.2
3.1
—
—
—
0
0
(43055514) Macroprolactin [Presence] in Serum or Plasma
7
6
11.96
4.30
2.0
1.0
—
—
—
0
0
(3000991) Gas panel - Venous blood
33
159
2.25
4.06
9.6
9.7
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
36
180
2.18
4.05
5.5
7.3
kpa
5.9
5.7
0.78
36
175
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
7
7
10.25
4.03
5.7
1.0
nmol/l
2.9
2.0
—
7
7
(3015377) Calcium [Moles/volume] in Serum or Plasma
70
445
1.81
3.98
3.0
2.4
mmol/l
2.4
2.4
0.55
63
400
(3013512) EKG study
51
295
1.93
3.88
3.9
2.8
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
38
198
2.09
3.85
2.1
1.7
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
140
1087
1.70
3.84
12.6
8.1
e9/l
4.5
3.9
2.08
126
955
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
183
1533
1.83
3.80
11.9
7.1
ml/min/173m2
105.2
100.0
2.24
140
1152
(3023183) Ammonium ion [Moles/volume] in Plasma
10
25
4.13
3.73
2.2
3.5
umol/l
29.0
34.8
—
10
20
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
70
453
1.77
3.72
2.6
2.3
u/l
48.4
56.8
1.71
63
420
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
6
6
10.21
3.51
1.3
1.5
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
10
27
3.82
3.39
1.3
1.3
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
147
1180
1.64
3.35
8.5
5.4
u/l
81.9
78.0
0.40
138
1114
(3024561) Albumin [Mass/volume] in Serum or Plasma
80
552
1.68
3.33
7.2
4.8
g/l
36.3
37.8
1.76
71
519
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
99
724
1.63
3.27
3.6
2.4
nmol/l
70.5
71.4
0.12
92
666
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
28
138
2.17
3.27
1.9
1.6
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
70
471
1.69
3.19
4.6
2.9
e6/l
40.9
52.4
0.19
55
357
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
35
191
1.98
3.14
2.8
3.4
ng/l
588.0
904.2
0.51
29
150
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
8
16
5.13
3.07
2.1
1.6
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
65
433
1.69
3.06
4.6
2.9
e6/l
0.5
0.3
0.42
51
321
(3020779) Urea [Moles/volume] in Serum or Plasma
27
136
2.11
2.99
16.5
7.9
mmol/l
8.3
6.3
0.97
27
131
(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture
5
5
10.17
2.99
2.4
2.8
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
51
320
1.75
2.97
4.4
2.4
e6/l
9.0
8.2
0.18
46
280
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
23
109
2.23
2.96
3.1
2.6
—
—
—
0
0
(1616796) Gas panel - Central venous blood
10
30
3.44
2.94
10.4
1.7
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
27
138
2.08
2.89
2.0
1.6
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
35
197
1.91
2.87
2.2
1.5
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
24
118
2.15
2.83
3.9
4.7
%
2.4
0.8
—
5
28
(4035726)
18
78
2.41
2.82
1.7
1.5
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
121
952
1.55
2.81
10.4
6.2
e9/l
0.6
0.5
2.15
107
845
(3020717) Zinc [Moles/volume] in Serum or Plasma
5
6
8.48
2.76
3.8
1.7
umol/l
29.6
11.2
—
5
6
(3006315) Basophils [#/volume] in Blood
121
956
1.54
2.74
10.4
6.2
e9/l
0.0
0.0
0.51
107
848
(36304419) Bacteria [Presence] in Urine
64
438
1.63
2.69
4.6
2.8
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
126
1007
1.53
2.69
10.4
6.1
e9/l
2.1
2.0
0.42
114
914
(3027315) Oxygen [Partial pressure] in Blood
9
25
3.70
2.60
7.8
2.4
kpa
10.2
9.3
—
9
25
(3013290) Carbon dioxide [Partial pressure] in Blood
9
25
3.70
2.60
7.8
2.4
kpa
5.1
5.1
—
9
25
(3018133) Calcium [Moles/volume] in Urine
6
11
5.56
2.56
3.8
5.1
mmol/l
2.9
2.1
—
6
11
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
18
82
2.29
2.54
1.8
1.4
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
39
238
1.76
2.49
2.8
2.8
e6/l
7.9
3.7
0.90
23
122
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
8
22
3.72
2.38
1.6
1.7
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
10
35
2.94
2.33
1.9
1.6
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
40
252
1.71
2.29
2.6
2.7
e6/l
1.3
0.8
0.55
23
136
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
6
13
4.70
2.28
3.2
1.3
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
6
13
4.70
2.28
2.7
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
67
483
1.54
2.23
3.1
2.3
—
—
—
0
0
(3022145) Colonoscopy Study observation
26
145
1.89
2.21
1.4
1.4
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
171
1491
1.52
2.20
5.6
3.8
pmol/l
14.4
14.4
0.01
160
1365
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
60
424
1.55
2.18
3.8
2.4
ng/l
11.8
31.1
1.35
35
178
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
9
30
3.08
2.17
2.0
1.6
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
21
110
2.00
2.13
4.2
4.9
%
0.2
0.2
—
5
22
(3013115) Eosinophils [#/volume] in Blood
121
991
1.45
2.11
11.8
6.5
e9/l
0.2
0.2
1.53
109
886
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
7
20
3.57
2.07
1.0
1.3
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
18
90
2.08
2.06
6.0
3.7
e9/l
69.5
68.0
0.06
12
64
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
10
38
2.70
2.03
2.5
1.6
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
10
38
2.70
2.03
4.0
3.1
—
—
—
0
0
(40758558) Short blood count panel - Blood
65
480
1.49
1.91
10.8
7.5
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
218
2032
1.83
1.91
14.1
8.2
—
—
—
0
0
(44790048)
6
17
3.59
1.85
2.3
2.1
—
—
—
0
0
(44790047)
6
17
3.59
1.85
2.3
2.1
—
—
—
0
0
(44790049)
6
17
3.59
1.85
2.3
2.1
—
—
—
0
0
(44806118)
6
17
3.59
1.85
2.3
2.1
—
—
—
0
0
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
5
12
4.23
1.83
2.4
1.2
mmol/l
1.9
1.6
—
5
12
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
5
12
4.23
1.83
3.0
1.3
nmol/l
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
209
1931
1.66
1.82
12.1
7.4
u/l
28.1
26.9
0.33
204
1864
(1761482) Bacteria [#/volume] in Urine by Culture
9
35
2.63
1.82
4.7
2.7
—
—
—
0
0
(4306422)
9
35
2.63
1.82
1.2
1.2
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
76
584
1.44
1.82
5.5
3.4
e6/l
69.1
64.7
0.05
57
377
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
7
161
0.42
1.74
1.0
1.3
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
54
391
1.49
1.74
4.7
2.3
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
68
516
1.44
1.73
4.7
2.2
—
—
—
0
0
(3022313) Gas panel - Capillary blood
21
119
1.84
1.72
9.8
5.2
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
76
592
1.42
1.67
4.4
2.9
u/l
54.3
30.2
0.74
71
552
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
102
837
1.38
1.65
5.5
3.9
—
—
—
0
0
(3030981) Hyaline casts [#/volume] in Urine by Automated count
12
57
2.16
1.58
2.1
2.2
e6/l
0.3
0.1
0.56
12
52
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
171
1533
1.41
1.57
3.6
2.9
mmol/l
5.6
5.6
0.04
158
1404
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
8
33
2.47
1.55
4.0
4.1
%
51.6
55.7
—
8
33
(3030905) Polymorphonuclear cells [#/volume] in Blood
8
33
2.47
1.55
3.9
3.8
e9/l
3.4
4.1
—
8
33
(40768443) Skin Pathology biopsy report
11
51
2.21
1.53
1.3
1.1
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
107
894
1.36
1.52
14.3
8.3
e9/l
0.0
0.0
0.49
87
730
(3012516) Albumin [Mass/volume] in Urine
37
255
1.53
1.50
4.0
3.8
mg/l
1546.4
340.7
0.35
26
175
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
51
376
1.45
1.50
1.9
1.5
mmol/l
1.6
1.3
1.18
46
328
(3044889) 12 lead EKG panel
115
974
1.35
1.48
3.1
2.5
—
—
—
0
0
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
7
155
0.44
1.48
1.7
1.7
—
—
—
0
0
(3019060) Gas panel - Arterial blood
11
52
2.17
1.47
9.3
4.2
—
—
—
0
0
(4268621)
7
28
2.54
1.46
2.1
2.4
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
16
3.17
1.44
2.0
1.2
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
5
16
3.17
1.44
3.2
2.9
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
6
22
2.77
1.44
8.3
1.9
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
38
267
1.50
1.42
4.6
4.7
mg/mmol
3.1
17.4
2.63
25
182
(3009508) Creatinine [Moles/volume] in Urine
57
434
1.41
1.41
4.7
3.7
mmol/l
8.9
8.4
0.22
48
381
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
15
82
1.88
1.39
2.6
1.6
—
—
—
0
0
(4062490)
6
23
2.65
1.37
1.2
1.3
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
16
90
1.83
1.37
1.5
1.4
—
—
—
0
0
(3008757) Leukocyte morphology finding [Identifier] in Blood
5
17
2.98
1.36
8.2
4.2
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
11
54
2.09
1.35
21.6
8.2
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
23
145
1.65
1.35
10.8
4.6
mmol/l
1.1
1.3
0.09
18
104
(3009343) pH of Capillary blood
23
146
1.64
1.32
11.2
4.7
ph
7.4
7.4
—
5
10
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
8
34
2.40
1.30
1.1
1.2
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
8
34
2.40
1.30
1.1
1.2
—
—
—
0
0
(3020961) Endomysium IgA Ab [Titer] in Serum
8
158
0.49
1.30
1.3
1.2
—
144.0
—
0
5
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
23
147
1.62
1.28
11.2
4.6
kpa
5.1
5.0
0.44
23
139
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
13
70
1.91
1.26
1.5
1.6
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
166
1505
1.34
1.26
3.4
2.8
mmol/l
1.3
1.2
2.01
159
1417
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
187
1727
1.38
1.25
5.9
4.3
mu/l
1.7
1.7
0.71
178
1618
(3006245) CD3-CD19+ cells/100 cells in Blood
5
19
2.66
1.22
2.2
3.5
%
11.2
17.1
—
5
19
(44816844) Macroprolactin [Units/volume] in Serum or Plasma
10
50
2.04
1.18
5.4
1.2
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
148
1327
1.30
1.18
4.8
3.7
mmol/mol
37.7
37.5
0.07
143
1249
(3023511) Choriogonadotropin [Units/volume] in Urine
23
151
1.58
1.17
1.4
1.2
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
20
2.53
1.15
1.8
1.5
—
—
—
0
0
(1175426) CD3 cells/100 lymphocytes in Blood
5
20
2.53
1.15
5.2
3.2
%
76.8
66.8
—
5
20
(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
5
20
2.53
1.15
5.2
3.0
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
11
58
1.94
1.14
1.5
1.8
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
55
432
1.35
1.13
1.5
1.4
—
—
—
0
0
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
7
31
2.30
1.11
1.3
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
28
195
1.49
1.11
1.1
1.3
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
5
21
2.41
1.09
11.4
20.8
nmol/l
1964.4
1326.2
—
5
21
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
5
21
2.41
1.09
7.4
14.2
nmol/l
1092.8
767.7
—
5
21
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
5
21
2.41
1.09
2.0
1.2
—
—
—
0
0
(4198724)
5
21
2.41
1.09
3.8
1.8
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
36
266
1.42
1.06
1.4
1.5
titre
231.1
501.6
—
9
50
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
140
1257
1.27
1.05
4.4
3.0
u/l
35.5
32.6
0.28
129
1207
(3013707) Erythrocyte sedimentation rate by Westergren method
142
1280
1.27
1.02
5.0
3.5
mm/h
9.4
7.8
1.10
132
1196
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
35
460
0.72
1.00
1.8
1.6
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
39
296
1.38
0.99
1.2
1.3
iu/ml
60.5
19.8
0.45
13
84
(3017143) Hepatitis C virus Ab [Presence] in Serum
48
377
1.34
0.99
1.5
1.6
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
31
226
1.43
0.99
1.6
1.6
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
30
0.00
0.98
0.0
1.0
—
0.1
—
0
7
(21494755) Public health laboratory ask at order entry panel
19
278
0.66
0.97
1.1
1.3
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
11
62
1.81
0.96
3.5
2.5
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
16
102
1.61
0.93
1.0
1.1
—
—
—
0
0
(3007461) Platelets [#/volume] in Blood
228
2209
1.70
0.92
23.3
13.7
e9/l
273.3
261.2
1.93
221
2159
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
11
63
1.78
0.91
15.5
10.6
%
0.7
0.7
0.02
11
63
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
6
30
2.03
0.87
1.7
1.4
—
—
—
0
0
(3026361) Erythrocytes [#/volume] in Blood
228
2212
1.67
0.87
23.5
13.7
e12/l
4.6
4.6
0.07
221
2156
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
170
1581
1.26
0.86
3.7
3.0
mmol/l
1.4
1.5
0.44
164
1489
(3009542) Hematocrit [Volume Fraction] of Blood
204
1942
1.34
0.85
17.1
10.5
%
39.7
40.4
0.72
161
1658
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
171
1593
1.26
0.84
3.8
3.2
mmol/l
2.8
2.8
0.12
164
1494
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
12
73
1.68
0.83
2.3
5.6
g/l
3.1
3.2
0.19
12
68
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
13
81
1.64
0.83
29.7
12.4
mg/l
1.2
1.0
0.39
13
75
(36660697) Celiac disease serology panel - Serum
33
252
1.36
0.82
1.3
1.2
—
—
—
0
0
(3010813) Leukocytes [#/volume] in Blood
228
2215
1.64
0.82
23.6
13.7
e9/l
7.2
6.7
2.76
221
2155
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
60
500
1.27
0.81
1.7
1.5
pmol/l
98.7
98.0
0.04
29
256
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
19
131
1.49
0.81
4.8
4.6
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
64
751
0.80
0.80
2.3
1.9
—
—
—
0
0
(3015736) pH of Urine
81
701
1.24
0.79
4.2
2.9
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
170
1589
1.24
0.78
3.8
3.1
mmol/l
4.6
4.6
0.05
164
1503
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
18
124
1.49
0.77
3.4
3.1
%
26.2
32.0
1.32
12
88
(3037467) Urinalysis macro (dipstick) panel - Urine
140
1285
1.22
0.76
5.8
3.7
—
—
—
0
0
(3000492) Spirometry study
13
194
0.65
0.74
2.0
1.3
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
7
38
1.87
0.74
1.7
1.6
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
5
25
2.02
0.73
1.0
1.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
7
40
1.77
0.72
1.0
2.3
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
23
170
1.39
0.70
2.1
1.4
—
—
—
0
0
(3029634) Reagin Ab [Titer] in Serum by VDRL
7
41
1.73
0.70
2.0
1.9
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
26
197
1.36
0.69
1.1
1.3
iu/ml
147.5
175.1
—
7
79
(3035350) Ketones [Presence] in Urine by Test strip
99
885
1.20
0.69
4.4
3.0
estimate
0.0
0.0
0.00
20
181
(40761535) Cells panel - Urine sediment
14
94
1.52
0.68
5.9
3.0
—
—
—
0
0
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
7
43
1.65
0.67
1.3
1.1
—
—
—
0
0
(3028626) Oxygen [Partial pressure] in Capillary blood
15
103
1.49
0.66
12.7
4.7
kpa
10.1
9.8
0.21
15
98
(3045424) Erythrocytes [Presence] in Urine
5
28
1.80
0.66
1.2
1.2
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
5
28
1.80
0.66
1.0
1.0
—
—
—
0
0
(3002256) Pathology report gross observation
20
146
1.40
0.66
1.4
1.2
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
56
476
1.23
0.64
4.7
3.2
estimate
0.0
0.0
0.80
18
186
(3009261) Glucose [Presence] in Urine by Test strip
100
900
1.19
0.64
4.5
3.1
estimate
0.0
0.0
0.00
20
179
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
202
1939
1.27
0.64
17.2
9.0
mg/l
22.5
20.5
0.36
168
1412
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
10
63
1.61
0.63
16.8
10.6
%
1.0
1.3
—
10
63
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
8
50
1.62
0.62
1.0
1.1
—
—
—
0
0
(3041806) Other cells [#/volume] in Blood by Manual count
5
30
1.68
0.62
1.4
1.4
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
47
394
1.24
0.61
1.7
2.3
mg/l
4.5
1.1
0.55
30
277
(3048689) Calprotectin [Mass/mass] in Stool
41
339
1.25
0.60
2.5
2.7
ug/g
85.7
71.1
0.24
32
257
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
31
248
1.29
0.59
2.0
2.3
u/l
6482.2
4493.4
—
8
107
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
18
132
1.39
0.59
1.1
1.4
miu/ml
217.6
281.9
—
9
66
(3016879) Cocaine [Presence] in Urine
16
217
0.72
0.58
4.7
1.7
—
—
—
0
0
(3006184) Hemoglobin [Mass/volume] in Capillary blood
6
35
1.73
0.58
5.2
1.8
g/l
136.0
134.2
—
6
25
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
8
54
1.50
0.58
1.8
1.9
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
18
239
0.73
0.57
4.4
1.6
—
—
—
0
0
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
6
36
1.68
0.57
1.0
1.3
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
17
227
0.73
0.56
1.2
1.4
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
18
238
0.74
0.56
4.4
1.6
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
18
238
0.74
0.56
4.4
1.6
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
24
187
1.32
0.55
2.5
1.9
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
28
346
0.78
0.54
1.4
1.5
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
15
108
1.41
0.54
1.3
1.2
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
18
236
0.74
0.53
4.4
1.7
—
—
—
0
0
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
9
62
1.47
0.53
1.4
1.4
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
46
391
1.22
0.53
3.9
3.2
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
61
536
1.19
0.50
4.4
2.6
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
7
45
1.57
0.49
2.4
3.1
—
—
—
0
0
(3019225) pH of Specimen
14
102
1.40
0.48
6.1
4.5
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
10
68
1.49
0.47
1.1
1.5
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
7
49
1.44
0.46
1.1
1.1
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
48
419
1.18
0.43
4.6
2.8
kg/l
1.0
1.0
—
9
55
(3014051) Protein [Presence] in Urine by Test strip
5
31
1.63
0.43
1.0
1.7
—
—
—
0
0
(3010726) Horse dander IgE Ab [Units/volume] in Serum
6
93
0.64
0.43
1.2
1.1
—
5.3
—
0
23
(44816559) Phosphatidylethanol [Mass/volume] in Blood
8
56
1.44
0.43
1.1
1.2
—
—
—
0
0
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
50
439
1.18
0.42
3.0
2.2
mg/l
2.7
2.6
0.13
43
379
(3021601) Nitrite [Presence] in Urine by Test strip
96
886
1.14
0.42
6.6
4.3
estimate
0.0
0.0
0.00
18
187
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
20
248
0.79
0.41
1.8
2.0
—
—
—
0
0
(3011841) English Walnut IgE Ab [Units/volume] in Serum
0
15
0.00
0.41
0.0
1.0
—
3.4
—
0
10
(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3027231) Wheat IgE Ab [Units/volume] in Serum
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma
0
17
0.00
0.41
0.0
1.2
—
106.1
—
0
17
(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum
0
17
0.00
0.41
0.0
2.9
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
65
585
1.15
0.40
1.7
1.4
g/l
1.7
2.0
1.24
34
351
(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma
10
137
0.72
0.40
1.1
1.5
—
—
—
0
0
(3009550) Parvovirus B19 IgG Ab [Titer] in Serum
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
21
170
1.26
0.38
4.8
3.3
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
76
695
1.14
0.38
4.9
3.0
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
13
168
0.76
0.37
1.3
1.3
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
9
71
1.28
0.36
1.4
1.7
—
—
—
0
0
(4010399)
13
99
1.33
0.36
1.8
1.4
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
15
117
1.30
0.36
1.4
1.2
—
32.8
—
0
7
(3020891) Body temperature
6
43
1.41
0.35
2.3
6.8
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
71
651
1.13
0.34
1.5
1.5
u/ml
0.6
2.2
1.36
13
154
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
14
173
0.80
0.29
1.4
1.6
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
16
194
0.81
0.29
1.4
1.5
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
11
85
1.31
0.28
1.5
1.3
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
5
71
0.70
0.26
1.6
1.7
—
—
—
0
0
(3000620) Complement C3 [Mass/volume] in Serum or Plasma
9
74
1.22
0.25
2.0
1.5
g/l
1.2
1.2
—
9
69
(3048929) Epstein Barr virus Ab [Presence] in Serum
20
170
1.19
0.25
1.2
1.4
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
54
586
0.90
0.25
2.1
1.8
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
11
87
1.28
0.24
1.4
1.2
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
106
1009
1.09
0.24
4.5
2.8
ug/l
93.0
64.8
0.80
96
943
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
27
237
1.16
0.24
2.7
2.4
ng/l
2063.1
528.3
0.58
14
106
(1002224) Polysomnography panel
6
85
0.70
0.24
1.0
1.1
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
33
295
1.14
0.24
1.2
1.2
u/ml
3.0
7.7
0.96
12
132
(3008898) HLA-B27 [Presence]
11
136
0.80
0.23
1.1
1.1
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
5
39
1.29
0.23
2.0
1.8
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
16
188
0.84
0.22
2.3
1.6
—
—
—
0
0
(3029396) Erythrocyte agglutination [Presence] in Blood
0
11
0.00
0.21
0.0
3.4
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
10
0.00
0.21
0.0
4.1
—
128.7
—
0
10
(40761995) Spermatozoa Progressive [#/volume] in Semen
0
10
0.00
0.21
0.0
3.9
—
—
—
0
0
(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3014043) Spermatozoa Nonprogressive/100 spermatozoa in Semen
0
10
0.00
0.21
0.0
7.8
—
—
—
0
0
(3001684) Respiratory syncytial virus Ag [Presence] in Specimen
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(42528717) Cashew nut recombinant (rAna o) 3 IgE Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
1.0
—
1.3
—
0
9
(3014148) Varicella zoster virus Ab [Titer] in Serum
6
50
1.21
0.20
1.5
1.2
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
15
175
0.85
0.19
3.0
2.1
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
6
52
1.16
0.19
2.7
1.8
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
6
52
1.16
0.19
1.3
1.1
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
7
63
1.11
0.17
1.4
2.1
—
—
—
0
0
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
15
130
1.16
0.16
2.7
2.2
—
20.3
—
0
5
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
9
83
1.09
0.15
1.1
1.5
—
—
—
0
0
(3050129) First trimester maternal screen panel - Serum or Plasma
21
232
0.90
0.14
1.2
1.5
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
15
132
1.15
0.13
1.1
1.1
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
50
475
1.07
0.12
5.7
4.1
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
62
645
0.95
0.10
2.3
2.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
5
47
1.07
0.09
1.4
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
5
47
1.07
0.09
1.4
1.1
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
6
54
1.11
0.09
2.3
2.0
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
7
65
1.08
0.08
1.9
1.6
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
61
591
1.04
0.07
2.4
1.7
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
7
85
0.82
0.07
1.1
1.2
—
—
—
0
0
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
9
104
0.86
0.06
1.3
1.4
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
64
657
0.96
0.06
1.8
1.8
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
67
656
1.03
0.04
2.4
2.0
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
39
378
1.04
0.04
1.8
1.9
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
44
452
0.97
0.04
2.6
2.0
—
—
—
0
0
(3003338) MCHC [Mass/volume]
184
1828
1.03
0.03
19.1
11.6
g/l
332.9
334.4
1.18
184
1813
(3005033) Fetal Nuchal fold Thickness US
15
141
1.07
0.03
1.3
1.4
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
10
92
1.09
0.03
1.5
1.7
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
15
142
1.06
0.02
1.3
1.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
74
730
1.02
0.02
1.5
1.8
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
185
1858
0.98
0.01
4.7
4.0
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
71
702
1.02
0.01
2.6
2.4
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
17
176
0.96
0.00
1.3
1.4
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
17
176
0.96
0.00
1.3
1.4
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
19
184
1.04
0.00
1.1
1.1
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
11
108
1.02
0.00
3.1
1.9
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
13
128
1.02
0.00
2.1
2.0
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
82
822
1.00
0.00
2.6
2.2
—
—
—
0
0
(3022621) pH of Urine by Test strip
10
97
1.03
0.00
3.8
2.2
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
17
175
0.97
0.00
1.2
1.4
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
17
175
0.97
0.00
1.2
1.4
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
15
145
1.04
0.00
1.3
1.5
—
—
—
0
0
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
10
105
0.95
0.00
1.1
1.2
u/ml
0.2
2.6
—
5
54
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
6
69
0.87
0.00
1.5
1.3
—
—
—
0
0
(3036782) Glucose [Moles/volume] in Pleural fluid
0
8
0.00
0.00
0.0
1.3
—
5.7
—
0
8
(42529406) Shigella sp [Presence] in Stool by Culture
5
51
0.98
0.00
1.4
1.2
—
—
—
0
0
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
5
51
0.98
0.00
1.0
1.2
—
13.7
—
0
7
(3028433) Virus identified in Specimen by Culture
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3016921) Smith extractable nuclear Ab [Units/volume] in Serum
5
50
1.00
0.00
1.0
1.2
—
4.0
—
0
5
(4281824)
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
8
79
1.01
0.00
1.1
1.1
—
—
—
0
0
(3002621) Streptococcal DNAse B [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010464) Parainfluenza virus 1 Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021578) Parainfluenza virus 2 Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40760435) Tropomyosin IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4024509)
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3007566) Smooth muscle Ab [Titer] in Serum
6
59
1.02
0.00
1.3
1.5
—
60.0
—
0
7
(3012741) Chlamydophila pneumoniae IgA Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(4211845)
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(3011436) Histone Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(44806071)
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
6
0.00
0.00
0.0
1.2
—
301.9
—
0
6
(3005880) Parainfluenza virus 3 Ag [Presence] in Specimen
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022192) Triglyceride [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003434) Protein [Mass/volume] in Pleural fluid
0
5
0.00
0.00
0.0
1.4
—
28.0
—
0
5
(3032868) Hemoglobin electrophoresis panel in Blood
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(4146454)
0
9
0.00
0.00
0.0
2.4
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
6
59
1.02
0.00
1.5
1.5
—
—
—
0
0
(3032352) Blasts [#/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014300) Beta 2 glycoprotein 1 IgM Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3029715) Chromosome analysis.interphase [Interpretation] in Bone marrow by FISH Narrative
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004446) Plasmodium sp identified in Blood by Light microscopy
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(3006653) Thiamine [Moles/volume] in Blood
0
6
0.00
0.00
0.0
2.0
—
176.6
—
0
6
(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(43055222) Platelet function.collagen + Adenosine diphosphate induced and EPINEPHrine induced panel - Blood
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_PRECOXCENTPUB and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_PRECOXCENTPUB.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: E4_PRECOXCENTPUB – Precocious central puberty

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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