Malignant neoplasm of hypopharynx, including Hilmo

C3_HYPOPHARYNX_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C12&, C13
  • Hospital discharge: ICD-9 148
  • Hospital discharge: ICD-8 148
  • Cause of death: ICD-10 C12&, C13
  • Cause of death: ICD-9 148
  • Cause of death: ICD-8 148
  • Cancer registry: Topography ICD-O-3 C1[23]
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

244

4. Check minimum number of events

None

244

5. Include endpoints

244

6. Filter based on genotype QC (FinnGen only)

237

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 237 40 197
Unadjusted period prevalence (%) 0.08 0.01 0.09
Median age at first event (years) 68.11 65.17 68.70

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
244
Matched controls
2440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UJC01
NOMESCO Finland
Scopy of lower throat
286.4
276.4
132
10
130
Kela drug reimbursment
Malignant tumour
+∞
173.3
145
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
700.3
146.9
131
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
418.5
136.2
125
6
A03FA01
ATC
metoclopramide; systemic, rectal
21.7
131.8
129
120
C13.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of hypopharynx
+∞
109.9
97
*
WF002
NOMESCO Finland
Radical radiotherapy
1564.5
106.7
96
*
C13.9
ICD-10 Finland
Malignant neoplasm: Hypopharynx, unspecified
+∞
100.1
89
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
49.4
99.8
60
16
R4190
NOMESCO Finland
Nutritional therapy
42.0
84.9
53
16
N02AA05
ATC
oxycodone; systemic
11.4
80.5
118
185
8070/3-C13.9
ICD-O-3
Squamous cell carcinoma, NOS, of hypopharynx, NOS
+∞
79.6
72
*
XX3DW
NOMESCO Finland
Time consuming IT work
20.5
73.5
61
39
A04AA01
ATC
ondansetron; systemic, rectal
37.6
71.7
46
15
Z51.5
ICD-10 Finland
Palliative care
18.4
63.4
55
38
H02AB02
ATC
dexamethasone; systemic
105.3
59.3
63
8
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
57.6
53
*
GBB00
NOMESCO Finland
Tracheostomy
89.7
56.3
61
9
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
22.9
54.8
42
22
EP1AE
NOMESCO Finland
Neck ultrasound examination
17.4
53.4
47
33
UDQ12
NOMESCO Finland
Flexible laryngoscopy
12.1
53.0
60
64
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
9.9
51.7
70
95
C12
ICD-10 Finland
Malignant neoplasm of piriform sinus
+∞
46.3
43
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
529.5
45.8
44
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
44.1
41
*
R13
ICD-10 Finland
Dysphagia
9.1
43.8
62
88
WZC00
NOMESCO Finland
Treatment plan or consultation
6.0
43.5
122
347
C13.1
ICD-10 Finland
Malignant neoplasm: Aryepiglottic fold, hypopharyngeal aspect
+∞
43.0
40
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
129.8
41.2
43
*
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
245.1
41.2
41
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
18.6
40.8
34
21
UJC02
NOMESCO Finland
Rigid oesophagoscopy
74.1
38.6
43
7
A04AA02
ATC
granisetron; systemic, transdermal
+∞
38.6
36
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
7.9
38.1
61
99
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
10.0
37.3
47
57
UDH02
NOMESCO Finland
Rhinopharyngoscopy
8.9
37.2
52
72
GD1AD
NOMESCO Finland
Thorax CT examination
9.8
35.4
45
55
D10.7
ICD-10 Finland
Benign neoplasm: Hypopharynx
+∞
35.3
33
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
35.3
33
*
C13.2
ICD-10 Finland
Malignant neoplasm: Posterior wall of hypopharynx
+∞
34.2
32
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
86.6
33.9
37
5
EBA15
NOMESCO Finland
Extraction of multiple teeth
10.0
32.3
40
47
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.1
31.8
55
96
WX408
NOMESCO Finland
General anesthesy, balanced
4.9
31.5
102
314
UDQ22
NOMESCO Finland
Microlaryngoscopy
67.7
31.0
35
6
ZX090
NOMESCO Finland
Other technic of radiotherapy
342.5
30.5
30
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
9.8
30.5
38
45
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
29.8
28
*
C32.1
ICD-10 Finland
Malignant neoplasm: Supraglottis
+∞
29.8
28
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
75.9
29.7
33
5
WX402
NOMESCO Finland
General anaesthesia
5.0
27.9
76
201
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
27.6
26
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
26.5
25
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
289.6
26.2
26
*
WZC30
NOMESCO Finland
Teaching
5.2
25.7
64
156
EBA10
NOMESCO Finland
Operative extraction of tooth
6.3
25.6
49
94
C32.0
ICD-10 Finland
Malignant neoplasm: Glottis
+∞
25.5
24
*
C13.0
ICD-10 Finland
Malignant neoplasm: Postcricoid region
+∞
25.5
24
*
JN4BD
NOMESCO Finland
Extensive body CT
7.9
25.4
38
56
DQA10
NOMESCO Finland
Biopsy of larynx
144.8
25.1
26
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
24.4
23
*
8070/3-C32.9
ICD-O-3
Squamous cell carcinoma, NOS, of larynx, NOS
+∞
23.3
22
*
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
44.8
23.2
28
7
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
9.8
22.9
28
32
R07.0
ICD-10 Finland
Pain in throat
8.2
22.6
32
44
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
22.2
21
*
DQE00
NOMESCO Finland
Implantation of prosthetic replacement for larynx
+∞
21.1
20
*
ENA10
NOMESCO Finland
Biopsy of pharynx
+∞
21.1
20
*
A07AA02
ATC
nystatin; oral
7.3
21.0
33
51
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
120.4
20.9
22
*
ZXE00
NOMESCO Finland
One hour or less
3.5
20.6
123
551
UJC12
NOMESCO Finland
Flexible oesophagoscopy
53.0
20.6
24
5
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
63.1
20.3
23
*
C32.9
ICD-10 Finland
Malignant neoplasm: Larynx, unspecified
+∞
20.1
19
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
80.0
20.0
22
*
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
80.0
20.0
22
*
A06AD11
ATC
lactulose; oral
3.9
19.4
72
235
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.2
19.0
60
174
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
19.0
18
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
19.0
18
*
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
+∞
19.0
18
*
WX002
NOMESCO Finland
Sedation and analgesia
3.8
18.8
74
251
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
205.1
18.8
19
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
205.1
18.8
19
*
TJD20
NOMESCO Finland
Change of gastrostomy tube
205.1
18.8
19
*
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
72.2
18.0
20
*
DQB30
NOMESCO Finland
Laryngectomy
+∞
17.9
17
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
17.9
17
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
193.5
17.8
18
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.2
17.6
124
599
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.2
17.0
98
420
8070/3-C12.9
ICD-O-3
Squamous cell carcinoma, NOS, of pyriform sinus
+∞
16.9
16
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
16.9
16
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
15.8
15
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
15.8
15
*
8070/3-C13.2
ICD-O-3
Squamous cell carcinoma, NOS, of posterior wall of hypopharynx
+∞
15.8
15
*
GBB13
NOMESCO Finland
Revision of tracheostomy
+∞
15.8
15
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
170.5
15.7
16
*
A02BC05
ATC
esomeprazole; systemic
2.9
15.4
124
634
WW500
NOMESCO Finland
Blood transfusion
15.3
15.4
25
18
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
7.4
15.1
23
34
ZXE10
NOMESCO Finland
More than one and less than three hours
3.0
14.9
105
497
A04AD12
ATC
aprepitant; systemic
+∞
14.7
14
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
14.7
14
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
159.1
14.6
15
*
D37.08
ICD-10 Finland
Tumor of uncertain or unknown nature in other part of lip, oral cavity and pharynx
159.1
14.6
15
*
UDQ02
NOMESCO Finland
Direct laryngoscopy
29.2
14.5
19
7
ZXD10
NOMESCO Finland
Scheduled procedure
2.8
14.2
113
568
K22.2
ICD-10 Finland
Oesophageal obstruction
32.2
14.1
18
6
Z2446
NOMESCO Finland
Social worker
5.4
13.7
29
60
PJD51
NOMESCO Finland
Block dissection of cervical lymph nodes
+∞
13.7
13
*
ENB30
NOMESCO Finland
Laryngopharyngectomy
+∞
13.7
13
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
13.7
13
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
13.7
13
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.5
13.6
54
181
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
10.3
13.4
26
28
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
42.6
13.3
16
*
N05CF01
ATC
zopiclone; oral
2.7
13.0
106
535
ZXB10
NOMESCO Finland
Medial
73.8
12.7
14
*
C32.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of larynx
+∞
12.6
12
*
TGB20
NOMESCO Finland
Tracheostomy tube replacement
+∞
12.6
12
*
SAA03
NOMESCO Finland
Extended examination of mouth
2.7
12.4
100
500
ZZA00
NOMESCO Finland
Split skin graft
10.9
12.3
23
23
ZXD05
NOMESCO Finland
Urgent procedure
2.7
11.8
92
450
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
11.6
68
286
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
11.6
135
798
R4110
NOMESCO Finland
Physiotherapy
2.8
11.6
77
347
D77
ICPC
Malignant digestive neopl other/NOS
+∞
11.5
11
*
JN4AD
NOMESCO Finland
Body CT examination
4.9
11.5
27
61
SBB10
NOMESCO Finland
Dental impressions
5.3
11.5
24
49
Z3226
NOMESCO Finland
Physiotherapist
3.1
11.2
57
221
R21
ICPC
Throat symptom/complaint
3.4
11.1
46
158
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
45.5
11.0
13
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
16.5
11.0
17
11
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
18.9
10.9
16
9
RD210, ,
NOMESCO Finland
15.1
10.7
17
12
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
10.5
10
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
10.5
10
*
WX707
NOMESCO Finland
Fiberoscopic intubation
+∞
10.5
10
*
116
Kela drug reimbursment
Prostate cancer
+∞
10.5
10
*
JDB00
NOMESCO Finland
Gastrostomy
+∞
10.5
10
*
R85
ICPC
Malignant neopl respiratory other
+∞
10.5
10
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.8
10.3
34
100
H03AA01
ATC
levothyroxine sodium; systemic
2.8
9.7
56
232
ZXE30
NOMESCO Finland
More than five and less than seven hours
7.4
9.6
22
32
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
31.4
9.5
12
*
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
+∞
9.4
9
*
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
+∞
9.4
9
*
DWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in surgery of ear, nose and larynx
+∞
9.4
9
*
UGB02
NOMESCO Finland
Tracheoscopy
+∞
9.4
9
*
8070/3-C13.1
ICD-O-3
Squamous cell carcinoma, NOS, of hypopharyngeal aspect of aryepiglottic fold
+∞
9.4
9
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
9.4
9
*
L01BC06
ATC
capecitabine; oral
+∞
9.4
9
*
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
4.1
9.1
26
69
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
13.2
9.0
15
12
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
6.9
8.7
21
33
Z43.1
ICD-10 Finland
Attention to gastrostomy
93.1
8.5
9
*
ZZR00
NOMESCO Finland
Flap of skin
93.1
8.5
9
*
RD160, ,
NOMESCO Finland
93.1
8.5
9
*
GBB96
NOMESCO Finland
Other tracheostomy procedure
93.1
8.5
9
*
SCA02
NOMESCO Finland
Preventive oral health care
3.9
8.4
26
73
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
8.4
8
*
ENB00
NOMESCO Finland
Excision or exploration of lesion of pharynx
+∞
8.4
8
*
Z93.1
ICD-10 Finland
Gastrostomy status
+∞
8.4
8
*
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
+∞
8.4
8
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
8.4
8
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
8.4
8
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
22.9
8.1
11
5
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
8.1
38
140
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
7.8
63
306
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
19.1
7.7
11
6
K08.3
ICD-10 Finland
Retained dental root
3.3
7.7
31
104
SAA04
NOMESCO Finland
Special examination of mouth
4.5
7.6
19
45
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.4
7.5
28
89
WX302
NOMESCO Finland
Thoracal epidural anesthesy
8.1
7.5
16
21
1420
FHL
Laryngomicroscopy
11.4
7.4
13
12
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
+∞
7.3
7
*
A79
ICPC
Malignancy NOS
+∞
7.3
7
*
C14.0
ICD-10 Finland
Malignant neoplasm: Pharynx, unspecified
+∞
7.3
7
*
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
JFB30
NOMESCO Finland
Right hemicolectomy
+∞
7.3
7
*
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
+∞
7.3
7
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
7.3
7
*
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
31.0
7.2
9
*
N05BA02
ATC
chlordiazepoxide; systemic
6.7
7.1
17
27
WX872
NOMESCO Finland
Intensive care
3.6
7.0
24
72
ZX120
NOMESCO Finland
Intravenous
3.5
6.9
24
73
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
6.9
90
530
A06AH03
ATC
naloxegol; oral
41.2
6.8
8
*
L03AA13
ATC
pegfilgrastim; parenteral
41.2
6.8
8
*
GD6AD
NOMESCO Finland
CT of chest and neck
23.3
6.7
9
*
SPF30
NOMESCO Finland
Relining of denture
8.2
6.7
14
18
N05BA01
ATC
diazepam; systemic, rectal
2.6
6.6
41
175
K02.1
ICD-10 Finland
Caries of dentine
2.0
6.5
126
850
Z3231
NOMESCO Finland
Registered nurse
2.2
6.5
70
381
L03AA02
ATC
filgrastim; parenteral
71.6
6.5
7
*
ZXC10
NOMESCO Finland
Use of laser
8.5
6.4
13
16
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
11.4
6.4
11
10
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.1
6.3
28
99
K05.31
ICD-10 Finland
Periodontitis pronounced
2.7
6.3
36
147
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
6.3
35
141
8070/3-C01.9
ICD-O-3
Squamous cell carcinoma, NOS, of base of tongue, NOS
+∞
6.3
6
*
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
+∞
6.3
6
*
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
+∞
6.3
6
*
C10.0
ICD-10 Finland
Malignant neoplasm: Vallecula
+∞
6.3
6
*
C10.3
ICD-10 Finland
Malignant neoplasm: Posterior wall of oropharynx
+∞
6.3
6
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
6.3
6
*
8070/3-C32.0
ICD-O-3
Squamous cell carcinoma, NOS, of glottis
+∞
6.3
6
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
6.3
6
*
GB3AV, ,
NOMESCO Finland
+∞
6.3
6
*
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
+∞
6.3
6
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
6.3
6
*
D37.09
ICD-10 Finland
Lip, oral cavity and pharynx
+∞
6.3
6
*
ENB20
NOMESCO Finland
Pharyngectomy
+∞
6.3
6
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.6
6.2
37
155
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
6.2
64
343
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
13.0
6.1
10
8
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
13.0
6.1
10
8
EBB10
NOMESCO Finland
Insertion of dental implant
13.0
6.1
10
8
B01AB05
ATC
enoxaparin; parenteral
2.1
6.1
76
437

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
81
48
24.76
102.63
1.4
1.2
—
—
—
0
0
128
442
4.99
34.72
3.4
1.5
—
—
—
0
0
124
495
4.06
26.07
3.8
2.2
—
—
—
0
0
117
521
3.39
19.56
5.4
2.0
2.33
2.34
mmol/l
0.31
111
434
139
718
3.17
17.58
4.0
2.4
—
—
—
0
0
159
910
3.15
16.39
12.5
5.8
4.69
4.45
e9/l
0.57
142
791
158
911
3.08
15.88
17.6
19.3
1.26
1.41
inr
1.00
46
237
44
118
4.33
15.30
1.5
1.1
—
—
—
0
0
106
508
2.92
14.70
5.6
3.9
—
—
—
0
0
60
211
3.44
14.10
2.1
1.8
—
—
—
0
0
83
356
3.02
13.97
9.0
4.1
—
—
—
0
0
97
470
2.77
12.85
5.7
3.1
7.40
7.40
ph
0.31
23
73
131
743
2.65
12.59
6.8
3.7
33.05
35.45
g/l
4.58
125
680
138
826
2.54
11.53
10.5
5.8
1.19
1.20
mmol/l
0.87
114
707
131
771
2.51
11.27
9.2
5.2
1.19
1.20
mmol/l
1.43
125
683
128
759
2.44
10.65
5.5
5.3
2.83
3.18
%
0.51
117
699
125
738
2.42
10.44
5.6
5.2
0.62
0.67
%
0.55
116
678
128
765
2.42
10.39
5.6
5.5
9.47
9.01
%
0.72
118
700
47
170
3.19
10.37
2.6
2.3
13.85
8.07
umol/l
0.46
42
149
29
80
3.98
9.59
2.4
1.4
2.38
2.73
ug/l
0.60
23
61
127
776
2.33
9.56
5.7
5.4
20.62
25.99
%
5.32
117
714
126
772
2.31
9.36
5.3
5.3
63.52
58.12
%
4.44
116
713
128
818
2.19
8.26
5.4
5.0
0.04
0.04
e9/l
1.08
107
708
127
814
2.17
8.08
5.4
5.0
0.65
0.62
e9/l
0.59
106
700
130
848
2.14
7.83
5.6
5.2
0.21
0.22
e9/l
0.14
109
739
128
832
2.13
7.76
5.3
5.1
1.47
1.79
e9/l
4.27
110
729
58
273
2.48
7.66
1.9
1.7
—
—
—
0
0
65
323
2.38
7.62
3.8
1.9
2.48
2.43
mmol/l
2.06
60
268
36
134
2.98
7.48
3.1
2.0
33.74
69.57
u/l
0.51
31
109
115
730
2.09
7.29
11.2
7.8
0.00
0.00
e9/l
0.24
96
604
74
399
2.23
7.12
1.4
1.3
—
—
—
0
0
9
5
18.61
6.31
1.6
1.8
—
—
—
0
0
114
759
1.94
6.00
6.6
5.5
—
—
—
0
0
64
348
2.14
5.91
2.9
2.6
526.70
561.49
mosm/kgh2o
0.57
57
282
84
522
1.93
5.30
3.0
2.9
33.29
212.27
e6/l
0.79
72
398
74
442
1.97
5.23
2.8
2.7
—
—
—
0
0
143
1759
0.55
4.86
3.3
4.8
1.41
1.36
mmol/l
0.60
127
1596
145
1776
0.55
4.84
3.4
4.8
4.28
4.39
mmol/l
0.51
132
1623
7
5
14.35
4.60
1.0
1.0
—
—
—
0
0
83
543
1.80
4.31
3.5
2.1
59.29
66.29
u/l
0.31
77
507
43
227
2.09
4.21
8.8
6.3
102.67
104.41
mmol/l
1.04
43
227
9
13
7.14
4.20
5.9
2.3
—
—
—
0
0
32
150
2.30
4.19
11.3
7.8
—
—
—
0
0
74
472
1.81
4.16
2.9
2.7
2.71
0.34
e6/l
0.51
63
349
7
7
10.25
4.03
7.1
1.9
—
—
—
0
0
141
1708
0.59
3.94
3.1
4.3
1.18
1.30
mmol/l
1.66
125
1538
87
597
1.71
3.75
3.4
3.4
124.07
77.38
e6/l
0.34
74
426
15
51
3.07
3.64
5.3
2.9
—
—
—
0
0
13
37
3.65
3.46
1.8
1.5
43.46
71.88
mmol/l
1.66
13
32
41
229
1.95
3.43
2.2
2.5
20.42
23.78
%
0.83
35
201
34
586
0.51
3.30
3.0
3.3
—
—
—
0
0
41
233
1.91
3.26
11.4
6.6
1.79
1.18
mmol/l
0.51
36
184
157
1820
0.61
3.15
3.9
5.4
2.42
2.58
mmol/l
1.25
135
1653
10
26
3.96
3.01
3.7
2.7
60.90
59.46
%
—
10
26
146
1713
0.63
2.97
4.3
6.4
37.90
40.97
mmol/mol
4.09
128
1570
67
455
1.65
2.91
2.0
2.0
2.85
2.82
mg/l
0.04
56
377
6
10
6.12
2.71
1.2
1.5
—
—
—
0
0
44
279
1.70
2.45
2.6
2.8
1.50
1.29
e6/l
0.13
25
160
11
38
2.98
2.45
5.1
2.7
—
—
—
0
0
94
1174
0.68
2.28
3.7
3.8
3.04
2.03
ug/l
0.48
80
1038
47
675
0.62
2.22
2.8
3.9
12.42
9.40
mg/mmol
0.27
30
434
7
19
3.76
2.16
1.7
1.3
—
—
—
0
0
8
191
0.40
2.16
1.1
1.4
—
—
—
0
0
8
26
3.15
2.03
4.1
2.1
3.82
5.01
e9/l
—
8
26
20
105
1.99
2.02
12.3
9.4
—
—
—
0
0
34
212
1.70
2.02
1.5
1.6
—
—
—
0
0
9
32
2.88
2.02
5.2
1.3
—
—
—
0
0
7
21
3.40
1.98
1.9
1.3
—
—
—
0
0
8
27
3.03
1.95
5.3
2.8
—
—
—
0
0
45
632
0.65
1.88
2.4
3.3
2551.64
261.92
mg/l
0.70
31
411
159
1768
0.71
1.71
4.2
4.8
5.83
6.12
mmol/l
3.21
143
1576
7
25
2.85
1.66
3.7
1.4
—
—
—
0
0
33
216
1.61
1.65
12.5
6.8
97.45
94.38
%
4.65
33
208
10
42
2.44
1.64
1.8
2.1
34.10
31.17
umol/l
—
10
36
6
20
3.05
1.59
1.3
1.2
—
—
—
0
0
131
1124
1.36
1.56
4.2
3.0
73.32
52.25
u/l
0.54
117
1033
139
1209
1.35
1.49
5.0
3.2
14.60
14.97
pmol/l
0.99
130
1058
66
829
0.72
1.47
3.5
3.6
0.00
0.00
estimate
-0.00
18
118
61
467
1.41
1.46
2.9
3.0
—
—
—
0
0
64
807
0.72
1.45
3.6
3.6
0.00
0.01
estimate
0.50
18
139
6
22
2.77
1.44
4.0
1.3
88.27
90.08
%
—
6
22
65
813
0.73
1.39
4.4
4.9
0.00
0.00
estimate
-0.00
18
125
9
42
2.19
1.35
2.9
3.2
—
—
—
0
0
6
24
2.54
1.31
1.5
1.2
—
—
—
0
0
8
36
2.26
1.25
1.3
1.2
—
—
—
0
0
9
169
0.51
1.24
4.6
3.2
—
—
—
0
0
8
37
2.20
1.22
2.5
2.8
0.89
1.00
nmol/l
—
8
27
13
71
1.88
1.22
1.0
1.1
108.47
93.64
iu/ml
—
6
25
5
20
2.53
1.15
1.6
1.3
21.20
18.08
u/ml
—
5
20
30
210
1.49
1.15
1.8
1.2
—
—
—
0
0
27
185
1.52
1.14
2.7
3.4
6.10
5.75
kpa
0.82
27
179
51
400
1.35
1.06
1.7
1.8
1360.56
1144.68
nmol/l
0.68
41
307
32
428
0.71
1.01
1.8
1.8
396.37
409.70
pmol/l
0.14
27
341
5
23
2.20
0.98
1.2
1.4
32.60
34.52
pg
—
5
23
0
29
0.00
0.98
0.0
5.2
—
7.29
—
0
24
92
790
1.26
0.98
2.0
2.1
83.51
92.05
pmol/l
1.25
55
430
15
94
1.63
0.93
3.7
4.7
25.71
24.87
mmol/l
0.44
15
88
18
119
1.55
0.91
5.3
3.2
—
—
—
0
0
17
111
1.57
0.90
3.9
4.2
—
—
—
0
0
158
1456
1.24
0.86
35.0
15.0
15.03
15.13
%
0.10
153
1425
54
651
0.78
0.84
2.4
2.6
0.66
0.76
ug/l
0.85
36
436
185
1952
0.78
0.84
43.3
19.3
7.28
6.85
e9/l
2.12
177
1877
11
65
1.72
0.84
1.4
1.5
—
—
—
0
0
185
1951
0.79
0.83
43.2
19.3
4.09
4.55
e12/l
19.25
176
1873
185
1950
0.79
0.82
43.8
19.4
37.25
40.62
%
15.27
171
1789
185
1950
0.79
0.82
43.2
19.3
254.12
233.63
e9/l
2.91
178
1883
23
165
1.43
0.81
1.4
1.6
—
—
—
0
0
141
1292
1.22
0.77
4.8
4.1
—
—
—
0
0
9
55
1.66
0.74
1.4
1.2
36.78
36.53
g/l
—
9
45
30
384
0.75
0.73
3.0
3.7
—
—
—
0
0
61
517
1.24
0.71
3.5
2.7
360.15
9707.51
umol/l
2.75
53
455
12
77
1.59
0.70
1.6
1.4
1.42
1.58
g/l
0.28
12
65
17
119
1.46
0.69
3.2
1.3
—
—
—
0
0
5
28
1.80
0.66
2.2
1.1
—
—
—
0
0
180
1887
0.82
0.63
36.8
15.7
76.52
87.04
umol/l
3.67
180
1887
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
3.2
—
—
—
0
0
17
124
1.40
0.57
1.4
1.4
—
—
—
0
0
16
116
1.41
0.56
1.4
1.5
—
—
—
0
0
9
135
0.65
0.53
1.9
1.5
—
—
—
0
0
6
100
0.59
0.53
2.7
3.4
—
—
—
0
0
37
438
0.82
0.50
3.6
3.1
—
—
—
0
0
135
1263
1.15
0.50
4.0
3.9
17.09
11.98
mm/h
1.93
122
1134
43
366
1.21
0.49
1.6
1.7
1.20
1.25
mg/l
0.05
33
283
181
1731
1.18
0.49
32.4
13.3
34.22
26.21
mg/l
2.64
168
1357
20
155
1.32
0.48
1.5
1.3
—
—
—
0
0
8
116
0.68
0.47
1.0
1.4
—
—
—
0
0
75
675
1.16
0.46
3.1
2.6
160.23
152.87
ug/l
0.10
65
604
15
113
1.35
0.44
4.0
4.0
0.25
0.29
%
—
8
31
42
484
0.84
0.43
1.6
1.7
1.14
1.41
mmol/l
2.28
37
404
11
79
1.41
0.41
1.5
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.9
—
7.95
—
0
11
0
17
0.00
0.41
0.0
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
2.14
—
0
11
0
19
0.00
0.39
0.0
1.1
—
0.39
—
0
11
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
7.40
—
0
11
20
161
1.26
0.38
1.4
1.4
—
—
—
0
0
19
153
1.26
0.36
4.0
3.9
5.25
5.13
kpa
0.28
19
146
39
442
0.86
0.34
4.4
3.7
0.00
0.03
estimate
0.50
17
118
15
119
1.28
0.32
4.4
4.0
0.00
0.06
%
—
7
32
19
156
1.24
0.32
6.7
4.2
—
—
—
0
0
178
1833
0.89
0.30
27.6
12.6
—
—
—
0
0
24
280
0.84
0.30
1.5
1.2
2.65
3.02
g/l
0.26
15
162
14
112
1.27
0.29
4.7
4.1
0.17
0.00
%
—
6
26
25
289
0.85
0.28
1.3
1.2
15.44
1.63
u/ml
—
5
78
55
598
0.90
0.26
5.0
4.1
—
—
—
0
0
10
127
0.78
0.26
2.0
3.2
—
—
—
0
0
184
1886
0.90
0.25
36.0
16.4
3.99
4.02
mmol/l
1.12
179
1821
9
76
1.19
0.25
2.9
1.9
—
—
—
0
0
18
152
1.20
0.24
3.1
2.9
4.97
4.54
kpa
0.29
18
145
15
125
1.21
0.23
4.4
3.9
0.29
0.81
%
—
7
39
5
39
1.29
0.23
1.2
1.2
—
—
—
0
0
12
98
1.24
0.21
1.1
1.2
—
—
—
0
0
5
42
1.19
0.21
1.2
1.2
—
—
—
0
0
12
145
0.82
0.21
10.6
6.3
26.40
24.22
mmol/l
1.06
12
138
0
10
0.00
0.21
0.0
2.2
—
847.60
—
0
10
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
12
99
1.22
0.20
1.7
2.4
—
—
—
0
0
11
90
1.23
0.19
3.7
3.9
—
—
—
0
0
6
52
1.16
0.19
2.0
1.1
—
0.18
—
0
5
184
1877
0.92
0.19
35.9
16.4
137.66
139.67
mmol/l
10.57
179
1812
121
1170
1.07
0.17
3.9
3.8
—
—
—
0
0
10
82
1.23
0.17
1.5
1.2
—
—
—
0
0
10
86
1.17
0.11
8.9
4.8
1.01
0.91
%
—
10
81
5
44
1.14
0.10
1.2
2.7
—
—
—
0
0
5
48
1.04
0.09
2.6
1.4
23601.40
11058.71
e6/l
—
5
38
11
97
1.14
0.09
1.5
1.3
0.91
1.13
g/l
0.39
11
88
6
54
1.11
0.09
2.0
1.6
—
—
—
0
0
5
60
0.83
0.08
4.0
2.8
26.40
24.39
mmol/l
—
5
60
82
798
1.04
0.08
3.6
4.0
29.56
51.78
ng/l
1.44
64
601
18
195
0.92
0.08
1.4
1.2
526.67
368.00
titre
—
6
45
5
64
0.78
0.08
1.4
1.5
—
—
—
0
0
10
88
1.14
0.08
8.9
4.6
2.14
1.69
%
—
10
83
159
1574
1.03
0.05
5.8
4.0
2.82
2.00
mu/l
2.38
150
1395
10
107
0.93
0.02
1.4
1.2
—
—
—
0
0
49
482
1.02
0.01
1.7
1.6
17.74
19.81
nmol/l
0.45
43
397
26
261
1.00
0.00
1.1
1.3
14.14
29.19
iu/ml
—
7
77
23
234
0.98
0.00
1.2
1.3
1.05
15.54
u/ml
—
6
82
18
175
1.03
0.00
7.4
3.6
—
—
—
0
0
8
80
1.00
-0.00
2.1
2.6
234.46
947.19
ug/l
—
8
75
0
5
0.00
-0.00
0.0
3.8
—
1.45
—
0
5
5
49
1.02
-0.00
1.8
2.6
6.84
7.71
kpa
—
5
49
0
5
0.00
-0.00
0.0
5.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
40466.67
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
1.15
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
83.29
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
2.20
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
0.17
—
0
8
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
48.7
—
186.83
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
3.34
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
98.20
—
0
5
0
9
0.00
-0.00
0.0
1.4
—
10.56
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
26.80
—
0
6
0
5
0.00
-0.00
0.0
6.2
—
—
—
0
0
9
98
0.92
-0.00
2.3
2.4
0.62
0.59
%
—
9
98

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_HYPOPHARYNX_WIDE – Malignant neoplasm of hypopharynx, including Hilmo

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).