Other and unspecified cicatricial alopecia

L12_HAIRLOSS_SCARNAS

androgenetic alopecia:

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L66.8, L66.9 Cause of death: ICD-10 — L66.8, L66.9 2 out of 7 registries used, show all original rules.	95
4. Check minimum number of events None	95
5. Include endpoints None	95
6. Filter based on genotype QC (FinnGen only)	94

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	L12_HAIRLOSS_SCARNAS
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L66[8-9]
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L66[8-9]
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other and unspecified cicatricial alopecia based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	559	452	105
Only index persons	544	440	104
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.02	0.00
Median age at first event (years)
Whole population	53.97	58.53	34.66
Only index persons	54.40	58.89	35.38

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	94	86	8
Unadjusted period prevalence (%)	0.03	0.03	0.00
Median age at first event (years)	61.43	62.30	52.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
95: Matched controls
950

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L66.9

ICD-10 Finland

Cicatricial alopecia, unspecified

+∞

79.8

L66.8

ICD-10 Finland

Other cicatricial alopecia

+∞

46.8

D07AD01

ATC

clobetasol; topical

16.4

43.9

102

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

13.7

32.6

P01BA02

ATC

hydroxychloroquine; oral

8.7

21.4

D07AC01

ATC

betamethasone; topical

7.6

20.3

237

L66.1

ICD-10 Finland

Lichen planopilaris

+∞

16.1

L30.9

ICD-10 Finland

Dermatitis, unspecified

5.4

14.0

109

D07XC01

ATC

betamethasone; topical

6.4

12.8

D07AC13

ATC

mometasone; topical

3.7

8.9

180

L63.9

ICD-10 Finland

Alopecia areata, unspecified

98.4

8.6

J01AA04

ATC

lymecycline; systemic

4.0

6.3

E000001, ,

ATC

3.2

6.1

131

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768443) Skin Pathology biopsy report

12.53

27.09

1.4

1.1

—

(3037522) Nuclear Ab [Titer] in Serum

119

4.45

10.80

1.3

1.4

311.11

613.71

titre

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

8.27

8.25

1.2

2.70

1.38

u/ml

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

7.67

7.88

3.6

2.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

385

2.76

5.25

7.1

6.2

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

5.33

4.36

1.2

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

5.78

4.29

2.9

1.6

0.20

0.22

g/l

0.26

(3030905) Polymorphonuclear cells [#/volume] in Blood

7.51

4.27

4.7

2.1

3.75

4.56

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

7.51

4.27

4.6

3.2

53.89

60.85

—

(3004616) Nuclear Ab [Presence] in Serum

6.13

3.42

1.0

1.1

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

9.04

3.31

1.0

1.1

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

666

2.95

3.24

4.9

4.2

14.66

14.95

pmol/l

0.57

590

(40768804) Tissue Pathology biopsy report

351

1.98

2.69

2.8

2.0

—

(3000494) Fungus identified in Specimen by Culture

2.36

2.54

1.2

1.5

—

(40761535) Cells panel - Urine sediment

2.60

2.54

3.1

3.8

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

192

2.01

2.46

1.5

1.2

0.41

1.80

u/ml

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

360

1.90

2.42

2.1

2.2

84.62

80.16

nmol/l

0.44

312

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

171

2.00

2.32

1.6

1.4

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

3.32

2.29

1.1

1.3

—

(3020961) Endomysium IgA Ab [Titer] in Serum

2.90

2.14

1.0

1.1

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

5.21

2.09

1.6

1.1

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

189

1.86

1.95

1.5

1.8

0.67

0.92

mg/l

0.93

152

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

4.33

1.84

1.4

1.2

—

nmol/l

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

4.33

1.84

1.2

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

766

2.29

1.75

14.5

13.2

80.20

80.13

ml/min/173m2

0.01

610

(3007853) Bacteria identified in Skin by Aerobe culture

2.21

1.75

1.1

1.4

—

(3035350) Ketones [Presence] in Urine by Test strip

416

1.69

1.70

5.8

4.1

0.00

estimate

-0.00

(3003327) Ova and parasites identified in Stool by Light microscopy

2.94

1.68

1.4

1.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

2.14

1.64

1.5

—

(40761536) Microorganisms panel - Urine sediment

2.19

1.63

5.5

4.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

420

1.66

1.61

6.6

5.6

0.00

estimate

-0.00

(3026008) Bacteria identified in Urine by Culture

290

1.66

1.55

2.9

3.2

—

(3009261) Glucose [Presence] in Urine by Test strip

423

1.64

1.54

5.8

4.1

0.00

estimate

-0.00

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

282

1.65

1.53

3.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

185

1.73

1.53

6.9

4.0

—

(3029937) Albumin [Presence] in Urine by Test strip

220

1.69

1.51

8.2

4.4

0.00

estimate

-0.00

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

312

1.62

1.47

6.5

4.3

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

3.24

1.45

1.0

1.6

—

(3007164) IgA [Mass/volume] in Serum or Plasma

175

1.67

1.31

1.3

1.4

2.54

2.56

g/l

0.02

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

257

1.57

1.25

2.1

2.4

62.07

53.92

u/l

0.63

231

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

531

1.55

1.19

2.6

2.8

46.71

42.93

u/l

0.21

496

(3018095) Leukocytes [#/volume] in Urine

290

1.52

1.13

3.6

4.1

67.69

73.28

e6/l

0.04

186

(3030467) Casts [#/volume] in Urine by Automated count

227

1.54

1.10

3.0

3.1

0.49

0.44

e6/l

0.04

155

(3002582) Erythrocytes [#/volume] in Urine

246

1.52

1.08

2.9

3.3

11.42

28.27

e6/l

1.60

174

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

175

1.58

1.08

1.4

1.3

19.90

35.16

iu/ml

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

293

1.49

1.06

2.5

3.0

2.36

mmol/l

0.03

257

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

832

2.10

1.02

5.5

5.1

2.87

2.81

mmol/l

0.25

754

(36304419) Bacteria [Presence] in Urine

222

1.51

1.01

3.0

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

2.02

0.99

1.9

1.5

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

824

1.92

0.97

5.0

4.5

4.87

4.81

mmol/l

0.26

759

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.96

0.96

1.0

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.81

0.95

3.6

2.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

577

1.47

0.92

6.0

4.5

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

810

1.88

0.92

5.1

4.7

5.75

5.85

mmol/l

0.47

739

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

165

1.52

0.89

1.2

1.3

12.07

9.90

u/ml

—

(3000330) Specific gravity of Urine by Test strip

1.89

0.88

2.3

3.9

—

(3044889) 12 lead EKG panel

590

1.46

0.88

4.2

3.8

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.65

0.88

9.5

7.3

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

411

1.40

0.83

5.1

6.2

1.21

1.22

mmol/l

0.57

345

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

231

1.44

0.82

2.5

3.1

1850.09

1013.03

ng/l

0.30

190

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

792

1.70

0.79

6.1

5.0

1.78

3.44

mu/l

0.55

711

(3001122) Ferritin [Mass/volume] in Serum or Plasma

346

1.38

0.78

3.4

2.5

221.85

92.17

ug/l

0.65

306

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.61

0.73

2.5

1.6

—

(3042936) Bacteria identified in Isolate by Culture

102

1.56

0.73

1.1

2.0

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.57

0.71

4.0

6.7

105.43

103.82

mmol/l

1.11

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.63

0.61

1.2

1.5

—

(3018572) Chloride [Moles/volume] in Blood

0.00

0.61

0.0

6.8

—

105.86

—

(3039000) Anion gap in Blood

0.00

0.61

0.0

6.8

—

10.14

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.61

0.0

1.2

—

(3002256) Pathology report gross observation

1.50

0.60

1.5

1.2

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.76

0.59

1.5

2.3

23.85

24.83

mmol/l

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.71

0.58

2.2

2.6

69.30

42.88

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

815

1.58

0.56

5.0

4.5

1.54

1.58

mmol/l

0.31

742

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.57

0.54

1.0

1.1

—

(3044640) Blood type and Crossmatch panel - Blood

247

1.31

0.53

2.4

2.2

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

382

1.28

0.53

4.5

5.1

1.22

mmol/l

0.02

343

(3019309) Folate [Moles/volume] in Red Blood Cells

155

1.37

0.52

1.7

1326.91

1175.81

nmol/l

0.23

107

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.56

0.49

1.6

2.6

123.43

129.20

g/l

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.53

0.49

1.1

2.1

—

(3012516) Albumin [Mass/volume] in Urine

232

1.29

0.47

3.1

3.0

7.75

341.76

mg/l

0.56

134

(3028026) IgM [Mass/volume] in Serum or Plasma

1.46

0.47

1.0

1.7

0.94

1.15

g/l

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

349

1.25

0.45

4.0

3.9

35.84

35.72

g/l

0.06

325

(4200892) Spirometry reversibility

1.44

0.43

1.6

1.2

—

(3020891) Body temperature

1.59

0.43

1.2

3.9

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.54

0.42

3.2

1.7

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.41

0.0

1.0

—

(3024928) Oxygen saturation in Venous blood

0.00

0.41

0.0

2.7

—

(3000991) Gas panel - Venous blood

1.36

0.41

7.5

7.3

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.41

0.0

1.4

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.41

0.0

1.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

521

1.24

0.41

2.8

3.0

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

0.00

0.40

0.0

1.0

—

3.15

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

782

1.36

0.40

4.8

4.0

1.25

1.24

mmol/l

0.06

711

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.40

0.40

3.0

1.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

228

1.26

0.39

4.5

3.9

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.41

0.39

1.4

1.6

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.34

0.38

3.3

1.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.40

0.38

1.1

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.38

0.38

4.9

3.4

—

(3009508) Creatinine [Moles/volume] in Urine

239

1.24

0.37

3.0

2.8

6.49

6.98

mmol/l

0.26

196

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.49

0.37

1.3

1.4

—

(40758558) Short blood count panel - Blood

211

1.25

0.36

3.6

7.5

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.46

0.36

1.3

1.2

—

(3019225) pH of Specimen

1.41

0.36

3.1

3.4

—

(3023368) Bacteria identified in Blood by Culture

183

1.26

0.36

3.2

4.0

—

(3020682) Albumin/Creatinine [Ratio] in Urine

240

1.24

0.36

3.9

3.3

1.99

6.12

mg/mmol

1.47

136

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

137

1.29

0.35

2.5

2.7

1.28

1.01

e6/l

0.35

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

819

1.36

0.33

15.7

13.2

16.01

19.02

mg/l

0.61

622

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

111

1.31

0.32

1.2

1.6

—

(36660697) Celiac disease serology panel - Serum

1.27

0.28

1.1

—

(40768797) Stomach Pathology biopsy report

132

1.26

0.28

1.2

—

(3003694) ABO and Rh group [Type] in Blood

222

0.82

0.27

1.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

161

1.23

0.27

1.5

1.6

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

0.73

0.25

7.0

7.9

134.83

119.35

g/l

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

387

1.15

0.23

2.7

2.5

—

(3009343) pH of Capillary blood

1.30

0.23

2.0

3.2

—

7.45

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.30

0.23

1.2

2.1

0.54

0.73

—

(3018418) pH of Serum or Plasma

270

1.16

0.22

3.2

3.8

7.40

—

(3022145) Colonoscopy Study observation

1.26

0.22

1.5

1.3

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.23

0.22

1.2

2.1

0.74

1.34

—

(3045414) Leukocytes [Presence] in Urine

1.23

0.22

2.4

1.9

—

(3044941) Cell count panel - Synovial fluid

0.00

0.21

0.0

1.6

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(4146454) Self-monitoring of blood glucose

0.00

0.21

0.0

2.5

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.3

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.1

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.4

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

3.7

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

1.8

—

4.13

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

1.8

—

107.31

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

1.8

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.3

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.27

0.20

7.0

7.8

0.65

0.68

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.24

0.20

7.0

7.7

1.28

1.66

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.20

0.0

1.6

—

17.71

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.20

0.0

8.0

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.21

0.20

1.3

1.2

—

(3013512) EKG study

253

1.15

0.20

6.5

3.5

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.25

0.19

1.7

2.6

95.29

82.40

ng/l

—

(21494755) Public health laboratory ask at order entry panel

1.25

0.19

1.9

1.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

343

1.13

0.18

1.9

89.91

99.98

pmol/l

0.69

150

(3022621) pH of Urine by Test strip

1.14

0.18

2.0

2.7

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

327

1.11

0.14

5.4

3.4

21.90

23.62

ng/l

0.09

217

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.20

0.13

1.3

2.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

182

1.13

0.12

2.0

2.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.18

0.11

1.3

2.1

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.12

0.09

1.0

1.4

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

128

1.11

0.07

2.5

2.9

8.78

4.67

e6/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

128

1.11

0.07

1.6

1.9

—

(3026493) Urate [Moles/volume] in Serum or Plasma

211

1.06

0.03

2.4

2.7

357.18

4775.16

umol/l

1.04

179

(3018677) aPTT in Platelet poor plasma by Coagulation assay

118

0.92

0.03

1.2

1.7

31.62

29.65

0.37

113

(3022217) INR in Platelet poor plasma by Coagulation assay

366

0.97

0.00

11.2

11.5

1.05

1.21

inr

1.85

116

(3021960) Folate [Moles/volume] in Serum or Plasma

193

0.98

0.00

1.6

1.5

23.77

23.55

nmol/l

0.01

153

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

775

1.04

0.00

7.3

5.6

38.11

39.37

mmol/mol

1.03

709

(1761868) Lipid panel - Serum or Plasma

284

0.98

0.00

3.4

2.9

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3011648) Oxygen content in Venous blood

0.00

0.0

2.6

—

10.74

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.0

1.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.1

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

4.1

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

1.1

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

1.4

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.1

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3012565) Volume of 24 hour Urine

0.00

0.0

1.4

—

2052.86

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.0

3.4

—

3.96

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

1.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.1

—

(3002079) Sodium [Moles/time] in 24 hour Urine

0.00

0.0

1.0

—

138.81

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.0

—

(40761511) CBC panel - Blood by Automated count

858

1.02

0.00

14.8

11.9

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

1.45

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.2

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.6

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.1

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.6

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.2

—

(3012544) pH of Venous blood

1.00

0.00

3.7

3.0

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

0.0

1.2

—

33.42

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.0

—

7.71

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.6

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

2.1

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

25.85

—

(3006270) Folate [Moles/volume] in Blood

0.00

0.0

1.0

—

396.71

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.2

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.4

—

(3036180) Methadone [Presence] in Urine

0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.2

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

0.91

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.2

—

(4035726) Immunohistochemistry procedure

0.95

-0.00

1.6

1.3

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

-0.00

0.0

1.5

—

514.67

—

(3020911) Cortisol [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.5

—

63.67

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.00

-0.00

1.8

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

130

1.00

-0.00

2.0

1.6

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

-0.00

0.0

1.0

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

1.0

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.6

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

0.98

-0.00

1.3

1.4

—

39.27

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

-0.00

0.0

1.0

—

(3000492) Spirometry study

0.90

-0.00

1.3

1.5

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_HAIRLOSS_SCARNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HAIRLOSS_SCARNAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_HAIRLOSS_SCARNAS – Other and unspecified cicatricial alopecia

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other and unspecified cicatricial alopecia

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints