Other and unspecified cicatricial alopecia

L12_HAIRLOSS_SCARNAS

androgenetic alopecia:

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L66.8, L66.9 Cause of death: ICD-10 — L66.8, L66.9 2 out of 7 registries used, show all original rules.	84
4. Check minimum number of events None	84
5. Include endpoints None	84
6. Filter based on genotype QC (FinnGen only)	84

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	L12_HAIRLOSS_SCARNAS
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L66[8-9]
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L66[8-9]
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other and unspecified cicatricial alopecia based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	559	452	105
Only index persons	544	440	104
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.02	0.00
Median age at first event (years)
Whole population	53.97	58.53	34.66
Only index persons	54.40	58.89	35.38

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	84	76	8
Unadjusted period prevalence (%)	0.02	0.03	0.00
Median age at first event (years)	61.58	62.58	52.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
73: Matched controls
731

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L66.9

ICD-10 Finland

Cicatricial alopecia, unspecified

+∞

59.8

L66.8

ICD-10 Finland

Other cicatricial alopecia

+∞

34.0

D07AD01

ATC

clobetasol; topical

17.8

26.2

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

11.0

14.2

D07AC01

ATC

betamethasone; topical

6.2

12.2

180

P01BA02

ATC

hydroxychloroquine; oral

9.2

11.8

L66.1

ICD-10 Finland

Lichen planopilaris

+∞

11.8

L30.9

ICD-10 Finland

Dermatitis, unspecified

5.1

7.8

D07XC01

ATC

betamethasone, combinations; topical

5.3

6.5

L65.9

ICD-10 Finland

Nonscarring hair loss, unspecified

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768443) Skin Pathology biopsy report

12.79

23.43

1.4

1.1

—

(3037522) Nuclear Ab [Titer] in Serum

103

4.63

10.11

1.4

311.1

560.0

titre

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

7.09

9.00

4.3

1.9

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

6.17

5.46

3.1

1.5

0.2

g/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

5.84

5.18

3.1

1.5

1.1

g/l

—

(40760892) CBC W Ordered Manual Differential panel - Blood

162

2.58

4.01

7.5

6.2

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

7.23

3.77

5.0

2.9

54.8

60.7

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

7.23

3.77

5.1

1.7

3.7

4.7

e9/l

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

6.19

3.43

1.4

1.3

—

(40768804) Tissue Pathology biopsy report

310

2.28

3.35

2.9

1.9

—

(42870588) Differential panel, method unspecified - Blood

232

2.27

3.31

4.8

4.7

—

(40761535) Cells panel - Urine sediment

2.93

3.07

3.1

3.5

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

584

2.91

2.90

5.0

4.3

14.7

15.0

pmol/l

0.40

515

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

168

2.22

2.87

1.5

1.2

0.4

2.1

u/ml

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

4.25

2.87

1.3

1.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

148

2.10

2.34

1.7

1.3

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

3.73

2.33

1.1

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.55

2.29

1.1

1.3

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

5.24

2.10

1.6

1.1

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

322

1.86

2.04

2.2

83.6

80.3

nmol/l

0.28

277

(3029937) Albumin [Presence] in Urine by Test strip

197

1.91

2.02

8.5

4.3

0.0

estimate

0.00

(3020961) Endomysium IgA Ab [Titer] in Serum

2.93

2.00

1.0

1.1

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

4.76

1.97

1.4

1.2

—

nmol/l

—

(3004616) Nuclear Ab [Presence] in Serum

4.76

1.97

1.2

1.1

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

4.76

1.97

1.2

—

(3035350) Ketones [Presence] in Urine by Test strip

374

1.83

1.93

6.1

4.1

0.0

estimate

0.00

(3003327) Ova and parasites identified in Stool by Light microscopy

3.37

1.92

1.4

1.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

168

1.89

1.86

7.1

3.9

—

(3021601) Nitrite [Presence] in Urine by Test strip

377

1.81

1.85

6.8

5.6

0.0

estimate

0.00

(3009261) Glucose [Presence] in Urine by Test strip

379

1.79

1.80

6.1

4.1

0.0

estimate

0.00

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

4.02

1.74

1.0

1.7

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

281

1.72

1.63

6.9

4.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

255

1.72

1.59

3.3

3.1

—

(3019832) Treponema pallidum Ab [Presence] in Serum

2.25

1.58

1.5

1.6

—

(40761536) Microorganisms panel - Urine sediment

2.25

1.58

5.9

4.2

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

675

2.32

1.57

15.3

13.4

80.1

79.6

ml/min/173m2

0.07

535

(3000494) Fungus identified in Specimen by Culture

2.04

1.52

1.2

1.5

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

2.54

1.42

1.9

1.2

—

(3018095) Leukocytes [#/volume] in Urine

262

1.65

1.40

3.7

4.0

70.1

56.0

e6/l

0.12

165

(3015736) pH of Urine

290

1.64

1.40

5.8

3.9

—

(3007164) IgA [Mass/volume] in Serum or Plasma

152

1.71

1.27

1.3

1.4

2.3

2.6

g/l

0.27

(3002582) Erythrocytes [#/volume] in Urine

223

1.62

1.24

3.0

3.2

11.7

28.3

e6/l

1.35

156

(3030467) Casts [#/volume] in Urine by Automated count

207

1.61

1.19

3.1

0.5

e6/l

0.01

140

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.37

1.13

1.0

—

(3044889) 12 lead EKG panel

523

1.61

1.10

4.2

3.8

—

(3037467) Urinalysis macro (dipstick) panel - Urine

513

1.59

1.09

6.2

4.6

—

(36304419) Bacteria [Presence] in Urine

202

1.58

1.09

3.1

2.9

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.98

1.04

3.6

2.2

—

(3026008) Bacteria identified in Urine by Culture

259

1.53

1.04

3.0

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

160

1.60

1.04

1.4

1.3

19.9

37.0

iu/ml

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.82

0.96

3.0

1.7

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

370

1.47

0.92

5.3

6.2

1.2

mmol/l

0.38

304

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

462

1.47

0.89

2.7

2.8

50.0

41.4

u/l

0.50

432

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.75

0.87

2.3

1.7

—

(3042936) Bacteria identified in Isolate by Culture

1.67

0.84

1.1

2.0

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

151

1.52

0.82

1.2

1.3

13.6

9.9

u/ml

—

(40758558) Short blood count panel - Blood

178

1.49

0.81

3.7

7.6

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.80

0.0

2.2

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

262

1.43

0.79

2.6

3.1

2.3

2.4

mmol/l

0.51

228

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.78

0.78

1.2

1.5

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.82

0.78

1.3

1.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.75

0.78

3.3

1.7

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

207

1.45

0.77

2.6

3.1

1889.6

1022.0

ng/l

0.28

170

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.65

0.77

10.5

7.3

—

(3000330) Specific gravity of Urine by Test strip

1.87

0.74

2.3

4.0

—

(3023368) Bacteria identified in Blood by Culture

163

1.47

0.74

3.2

4.1

—

(3002256) Pathology report gross observation

1.63

0.74

1.5

1.2

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.68

0.72

1.1

1.4

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

343

1.38

0.71

4.7

5.1

1.2

mmol/l

0.03

305

(3004588) Protein electrophoresis panel - Serum or Plasma

1.68

0.68

1.1

2.2

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

700

1.67

0.67

6.1

5.1

1.7

3.7

mu/l

0.56

626

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

738

1.80

0.67

5.6

5.2

2.8

mmol/l

0.12

666

(3001122) Ferritin [Mass/volume] in Serum or Plasma

298

1.36

0.66

3.6

2.5

249.6

95.2

ug/l

0.65

264

(3020891) Body temperature

1.77

0.65

1.2

3.3

—

(3018572) Chloride [Moles/volume] in Blood

0.00

0.61

0.0

6.8

—

105.9

—

(3039000) Anion gap in Blood

0.00

0.61

0.0

6.8

—

10.1

—

(3000991) Gas panel - Venous blood

1.53

0.59

7.5

7.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.77

0.59

1.3

1.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.72

0.58

1.0

1.1

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.62

0.55

1.3

1.2

—

(3022145) Colonoscopy Study observation

1.50

0.53

1.5

1.2

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

731

1.64

0.52

5.2

4.5

4.8

mmol/l

0.18

671

(3024561) Albumin [Mass/volume] in Serum or Plasma

307

1.30

0.51

4.3

3.8

35.5

35.7

g/l

0.12

286

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

724

1.52

0.50

5.2

4.5

1.5

1.6

mmol/l

0.29

656

(36660697) Celiac disease serology panel - Serum

1.47

0.44

1.1

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.65

0.44

1.6

2.4

23.4

24.9

mmol/l

—

(3018418) pH of Serum or Plasma

245

1.28

0.43

3.3

3.8

7.4

—

(3045414) Leukocytes [Presence] in Urine

1.55

0.42

2.4

1.8

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.41

0.0

1.7

—

(3024928) Oxygen saturation in Venous blood

0.00

0.41

0.0

3.1

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.50

0.41

2.4

2.7

64.4

43.8

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

2.3

—

(3012516) Albumin [Mass/volume] in Urine

209

1.28

0.40

3.2

2.9

7.2

386.1

mg/l

0.56

118

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.39

0.0

1.3

—

(3009343) pH of Capillary blood

1.41

0.39

2.0

3.3

—

7.5

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.41

0.38

5.3

3.5

—

(40768797) Stomach Pathology biopsy report

118

1.33

0.36

1.2

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.43

0.36

1.0

1.4

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.43

0.36

7.0

7.4

0.6

0.7

—

(3019309) Folate [Moles/volume] in Red Blood Cells

137

1.30

0.35

1.8

1.7

1430.0

1198.5

nmol/l

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.39

0.35

7.0

7.3

1.3

1.7

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.39

0.35

1.7

2.7

122.5

130.0

g/l

—

(3009508) Creatinine [Moles/volume] in Urine

213

1.25

0.34

3.1

2.7

6.6

7.0

mmol/l

0.19

174

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

698

1.35

0.34

4.9

4.0

1.3

1.2

mmol/l

0.29

631

(3026493) Urate [Moles/volume] in Serum or Plasma

185

1.26

0.34

2.4

2.7

357.2

5495.9

umol/l

1.04

154

(4010399)

1.38

0.32

1.6

1.2

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.35

0.32

1.7

2.7

95.3

82.3

ng/l

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

724

1.33

0.30

16.9

13.2

16.5

19.4

mg/l

0.52

544

(3041096) Erythrocytes [Presence] in Urine by Automated

207

1.22

0.29

4.8

3.9

—

(3019225) pH of Specimen

1.28

0.28

3.1

3.3

—

(3020682) Albumin/Creatinine [Ratio] in Urine

218

1.21

0.27

3.8

3.5

2.2

6.2

mg/mmol

1.24

119

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.22

0.26

1.3

2.0

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

134

1.24

0.25

1.4

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.28

0.24

1.3

1.6

—

(3003694) ABO and Rh group [Type] in Blood

198

0.82

0.24

1.4

1.3

—

(3002385) Erythrocyte distribution width [Ratio]

622

1.20

0.23

17.9

16.8

13.3

13.7

2.39

609

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

290

1.17

0.23

5.7

3.5

22.3

22.9

ng/l

0.03

198

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.27

0.23

1.2

2.1

0.7

1.3

—

(21494755) Public health laboratory ask at order entry panel

1.20

0.22

2.0

1.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

301

1.16

0.21

1.9

93.1

98.8

pmol/l

0.34

134

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

2.2

—

(3044941) Cell count panel - Synovial fluid

0.00

0.21

0.0

1.7

—

(4146454)

0.00

0.21

0.0

2.5

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.3

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.21

0.0

1.5

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

1.8

—

107.3

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.21

0.0

8.5

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

1.8

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

1.8

—

4.1

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.20

0.0

1.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

110

1.22

0.18

1.6

2.0

—

(3032080) INR in Blood by Coagulation assay

285

1.14

0.17

5.7

8.7

1.1

1.2

inr

1.23

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.19

0.16

1.3

2.1

—

(3009542) Hematocrit [Volume Fraction] of Blood

659

1.17

0.16

14.3

13.9

39.9

39.6

0.12

460

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

446

1.12

0.16

2.9

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

106

0.83

0.14

1.2

1.7

31.3

29.5

—

101

(3028026) IgM [Mass/volume] in Serum or Plasma

1.17

0.10

1.0

1.7

0.8

1.1

g/l

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.14

0.10

1.8

1.9

—

(3000492) Spirometry study

1.14

0.09

1.3

1.5

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.08

0.09

1.3

—

41.9

—

(3022621) pH of Urine by Test strip

1.08

0.09

2.2

2.5

—

(3013512) EKG study

225

1.09

0.08

6.8

3.6

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

0.81

0.08

7.0

7.9

134.8

119.9

g/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

110

1.11

0.05

2.0

1.6

—

(3021960) Folate [Moles/volume] in Serum or Plasma

164

1.05

0.00

1.6

1.5

23.9

23.8

nmol/l

0.01

129

(1761868) Lipid panel - Serum or Plasma

242

0.99

0.00

3.0

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

349

1.00

0.00

4.9

4.1

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

687

1.02

0.00

7.2

5.7

37.9

39.4

mmol/mol

1.32

629

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

165

0.96

0.00

2.1

2.2

—

(3044640) Blood type and Crossmatch panel - Blood

226

1.02

0.00

2.7

2.2

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.0

—

6.8

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

1.5

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.4

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.0

4.3

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.1

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

1.2

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.2

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

2.3

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.3

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.1

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

1.0

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.2

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

23.7

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.2

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.5

—

(40761511) CBC panel - Blood by Automated count

760

1.00

0.00

15.4

12.3

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.1

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

2.2

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

0.0

1.0

—

33.3

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.0

1.0

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.6

—

(4035726)

0.90

0.00

1.7

1.3

—

(3012565) Volume of 24 hour Urine

0.00

0.0

1.4

—

2052.9

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.1

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.6

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.0

1.0

—

(4027681)

0.00

0.0

1.0

—

(3011648) Oxygen content in Venous blood

0.00

0.0

2.6

—

10.7

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.0

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

0.9

—

(3012544) pH of Venous blood

0.97

0.00

4.2

3.2

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.0

3.4

—

4.0

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.6

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(3006270) Folate [Moles/volume] in Blood

0.00

0.0

1.0

—

405.8

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.1

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.2

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_HAIRLOSS_SCARNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HAIRLOSS_SCARNAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_HAIRLOSS_SCARNAS – Other and unspecified cicatricial alopecia

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other and unspecified cicatricial alopecia

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints