brain neoplasm: A neoplasm (disease) that involves the brain.
Melanocytic naevi of upper limb, including shoulder
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_MELANOCYTIC_UPPERLIMB
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
832 |
4. Check minimum number of eventsNone |
832 |
5. Include endpointsNone |
832 |
6. Filter based on genotype QC (FinnGen only) |
832 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D22
- Name in latin
- Naevus melanocyticus (cutis) regionis deltoideae
Similar endpoints
↥List of similar endpoints to
Melanocytic naevi of upper limb, including shoulder
based on the number of shared cases.
Similar with more cases:
- Melanocytic naevi of upper limb, including shoulder
- Melanocytic naevi
- Melanocytic naevi
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5751 | 3429 | 2304 |
| Only index persons | 5400 | 3265 | 2135 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.06 |
| Only index persons | 0.10 | 0.12 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 41.00 | 39.84 | 42.75 |
| Only index persons | 41.93 | 40.42 | 44.24 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 832 | 551 | 281 |
| Unadjusted period prevalence (%) | 0.17 | 0.19 | 0.12 |
| Median age at first event (years) | 52.08 | 46.90 | 62.24 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 741
- Matched controls
- 7410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
7292.4
323.0
702
18
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
67.4
236.0
269
62
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
12.1
136.5
276
345
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
13.5
120.5
225
231
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
10.4
80.7
169
204
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
14.9
57.7
99
76
L57.0
ICD-10 Finland
Actinic keratosis
6.9
57.5
156
275
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.8
53.8
147
260
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
8.2
47.5
112
158
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
6.9
46.8
125
212
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
16.5
41.9
68
45
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
32.2
41.1
54
18
2166A
ICD-9 Finland
Benign neoplasm of skin, Skin of upper limb, including shoulder[YLÄRAAJAN IHON BEN KASV,NAEVUS PIGMENTOSUS]
+∞
41.0
39
*
XQ845
NOMESCO Finland
Dermatoscopy
24.9
34.9
49
21
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
10.4
33.0
66
69
TQW99
NOMESCO Finland
Other minor procedure on skin
6.7
29.7
78
127
R23.8
ICD-10 Finland
Other and unspecified skin changes
3.2
28.6
173
641
XQ848
NOMESCO Finland
Dermatological photography
8.4
28.5
64
82
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
104.1
27.9
30
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
12.4
26.6
48
41
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
15.1
26.0
43
30
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
40.4
25.0
31
8
L82
ICD-10 Finland
Seborrhoeic keratosis
3.1
24.9
155
581
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
9.0
24.7
53
63
ZXC50
NOMESCO Finland
Cryotherapy
7.9
23.8
55
74
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.8
23.7
83
191
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
20.9
23.2
34
17
C43.69
ICD-10 Finland
Malignant melanoma of the upper extremity including shoulder other or unspecified histology
236.9
22.7
23
*
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
23.0
21.8
31
14
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
38.4
20.9
26
7
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
113.2
20.7
22
*
9733
FHL
Excision of skin change in operating room or anesthesia
12.1
19.9
36
31
QCE99
NOMESCO Finland
Other excision or repair of lesion of skin of upper limb
29.9
19.7
26
9
C43.60
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder without histology
107.9
19.7
21
*
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
47.3
19.3
23
5
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
56.6
19.0
22
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
9.1
18.6
39
45
S18
ICPC
Laceration/cut
2.0
17.3
325
2085
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
19.8
17.0
25
13
PJA12
NOMESCO Finland
Sentinel node biopsy
3.2
16.4
89
299
D23.6
ICD-10 Finland
Benign neoplasm: Skin of upper limb, including shoulder
15.8
16.3
26
17
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
34.2
15.8
20
6
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
+∞
14.6
14
*
127
Kela drug reimbursment
Transplant complication
8.6
14.1
30
36
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
16.1
14.0
22
14
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
11.7
13.9
25
22
S82
ICPC
Naevus/mole
2.5
13.6
115
510
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
11.2
13.1
24
22
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
6.3
13.0
34
56
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
6.3
13.0
34
56
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
12.6
12.7
22
18
ZQZ00
NOMESCO Finland
Treatment of several skin areas
17.7
12.6
19
11
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
27.2
12.1
16
6
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
47.4
11.9
14
*
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
15.0
11.8
19
13
C43.6
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of upper limb, including shoulder
+∞
11.5
11
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
3.3
11.5
58
186
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
17.4
11.2
17
10
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
10.8
10.8
20
19
Z94.0
ICD-10 Finland
Kidney transplant status
9.8
10.8
21
22
D03.5
ICD-10 Finland
Melanoma in situ of trunk
18.1
10.8
16
9
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
5.1
10.8
33
67
180
Kela drug reimbursment
Interferon alfa
28.5
10.7
14
5
TQW80
NOMESCO Finland
Local dermatologic skincare
4.9
10.7
34
72
L04AA06
ATC
mycophenolic acid; systemic
7.1
10.6
25
36
ZXC15
NOMESCO Finland
Use of photodynamic technique
9.3
10.1
20
22
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
8.0
9.7
21
27
C43.61
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder originating in lentigo maligna
101.2
9.4
10
*
C43
ICD-10 Finland
Malignant melanoma of skin
30.4
9.4
12
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.9
9.2
57
209
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
9.2
9.1
18
20
ZZR00
NOMESCO Finland
Flap of skin
4.7
8.7
28
61
L04AD01
ATC
ciclosporin; systemic
5.6
8.7
24
44
D06BB10
ATC
imiquimod; topical
3.1
8.6
45
149
D23.7
ICD-10 Finland
Benign neoplasm: Skin of lower limb, including hip
6.8
8.4
20
30
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
12.9
8.4
14
11
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
4.4
8.4
29
68
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
11.9
8.1
14
12
C43.5
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of trunk
17.4
8.1
12
7
SPAT1153
SPAT
Removal of sutures
1.7
8.0
223
1529
C43.99
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin other or unspecified histology
22.3
8.0
11
5
B07.9
ICD-10 Finland
Verruca simplex
3.3
7.9
38
119
L91.0
ICD-10 Finland
Hypertrophic scar
6.2
7.9
20
33
J01DB01
ATC
cefalexin; oral
1.7
7.9
588
5157
S77
ICPC
Malignant neoplasm of skin
9.5
7.8
15
16
C44.50
ICD-10 Finland
Malignant tumor of the skin on the torso without histology
18.6
7.6
11
6
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
7.2
7.5
17
24
C44.72
ICD-10 Finland
Spinocellular carcinoma of the skin of the lower extremity including the hip
80.8
7.4
8
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.5
7.3
15
18
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
9.5
7.3
14
15
C43.71
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip originating in lentigo maligna
+∞
7.3
7
*
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
3.3
7.3
34
105
L04AA01
ATC
[U] ciclosporin; systemic
5.9
7.3
19
33
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
20.2
7.1
10
5
S21
ICPC
Skin texture symptom/complaint
2.0
7.1
89
470
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.0
7.1
15
19
ZXC20
NOMESCO Finland
Use of chemical agents
6.1
7.1
18
30
QBE00
NOMESCO Finland
Excision of loose skin or fold of skin from trunk
10.2
7.0
13
13
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.9
6.9
21
44
E0000UV
ATC
NA
1.5
6.9
280
2100
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
4.2
6.9
24
58
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
40.4
6.8
8
*
C43.53
ICD-10 Finland
Malignant melanoma of the torso nodular
16.9
6.8
10
6
C43.51
ICD-10 Finland
Malignant melanoma of the trunk originating in lentigo maligna
22.7
6.7
9
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
4.7
6.4
20
43
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
11.1
6.3
11
10
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.5
6.2
20
45
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
7.8
6.1
13
17
S29
ICPC
Skin symptom/complaint other
1.8
6.1
114
693
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
12.6
6.1
10
8
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.5
6.1
26
76
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
10.1
6.0
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
27
40
6.94
17.50
1.8
1.5
15.0
7.1
ug/l
0.50
27
33
377
2729
1.70
12.31
6.6
4.5
35.8
35.9
g/l
0.14
350
2558
508
3983
1.71
12.28
11.9
8.7
3.8
4.0
e9/l
2.15
448
3487
14
14
10.15
12.26
1.0
2.0
1.1
2.2
ug/l
—
6
6
680
5927
1.81
9.81
21.0
15.8
13.7
13.6
%
0.96
669
5809
435
3426
1.57
9.10
7.4
5.9
11.1
11.0
umol/l
0.06
417
3247
92
478
2.04
8.63
4.7
3.8
96.7
79.9
ng/l
0.93
83
430
405
3183
1.53
8.26
9.7
6.6
1.2
1.2
mmol/l
0.07
345
2687
255
1811
1.59
8.18
3.6
2.9
0.2
0.5
e6/l
2.24
190
1342
86
453
2.00
7.76
3.1
2.9
204.6
192.5
ng/l
0.10
78
408
313
2352
1.53
7.72
4.2
3.1
—
—
—
0
0
596
5139
1.56
7.60
9.8
7.1
77.8
77.8
u/l
0.01
569
4836
33
119
2.85
6.97
8.1
5.0
328.3
357.5
iu/ml
—
8
14
563
4873
1.48
6.37
3.4
3.3
—
—
—
0
0
159
1064
1.61
6.37
2.7
2.6
1.1
1.1
e6/l
0.06
89
581
120
750
1.70
6.26
3.5
2.6
9.1
7.7
umol/l
0.31
110
643
361
2897
1.43
5.98
8.2
5.9
1.2
1.2
mmol/l
0.49
336
2626
33
130
2.60
5.93
3.7
3.8
61.0
57.0
%
1.05
33
130
32
125
2.62
5.85
3.4
3.5
4.5
4.3
e9/l
0.16
32
125
531
4580
1.44
5.85
5.0
4.2
28.1
2446.1
e6/l
—
7
67
223
1646
1.48
5.68
3.2
2.6
7235.9
6129.9
umol/l
0.10
197
1438
194
1397
1.51
5.56
3.2
2.4
3.3
6.9
e6/l
5.25
170
1215
351
2832
1.41
5.52
2.6
2.3
76.6
76.0
nmol/l
0.15
334
2537
44
205
2.21
5.51
3.0
2.6
3.4
3.7
g/l
0.68
44
194
95
577
1.73
5.49
4.8
3.9
1.4
1.9
mmol/l
0.60
77
452
414
3445
1.40
5.41
5.1
4.7
0.0
0.0
estimate
0.50
79
707
51
256
2.06
5.30
1.7
2.1
1.3
1.5
g/l
0.79
43
224
572
5043
1.43
5.29
4.9
3.9
10.5
11.4
mm/h
0.98
530
4665
109
701
1.64
5.09
1.9
1.8
—
—
—
0
0
394
3274
1.39
5.08
4.8
4.0
—
—
—
0
0
286
2252
1.41
5.06
3.9
3.0
28.2
31.4
u/l
1.42
274
2149
743
6933
1.67
5.00
17.0
12.8
22.1
22.4
mg/l
0.09
584
5413
415
3487
1.38
4.95
3.8
3.5
0.0
0.0
estimate
0.50
80
680
407
3431
1.36
4.66
3.9
3.5
0.0
0.0
estimate
0.00
74
694
51
272
1.93
4.51
1.5
1.4
—
—
—
0
0
604
5447
1.40
4.39
4.3
4.0
14.7
14.6
pmol/l
0.41
564
4980
277
2213
1.38
4.38
4.5
3.2
2.3
2.4
mmol/l
0.66
248
1955
105
698
1.58
4.29
1.9
1.7
—
—
—
0
0
142
1014
1.48
4.17
2.9
2.8
2.8
3.1
e6/l
0.12
71
537
137
972
1.49
4.15
2.6
2.0
29.4
29.6
s
0.21
131
943
142
1016
1.48
4.13
5.7
3.4
0.8
0.8
mmol/l
0.11
131
954
144
1036
1.47
4.07
3.2
2.3
12.9
13.3
umol/l
0.35
139
949
199
1528
1.40
3.94
2.0
1.7
2.4
1.1
mg/l
0.72
151
1157
73
453
1.67
3.94
1.6
1.6
—
—
—
0
0
33
160
2.11
3.81
2.1
1.7
39.2
821.4
e6/l
0.59
25
128
33
160
2.11
3.81
2.1
1.6
7.3
9.6
e6/l
0.14
25
123
98
660
1.55
3.79
5.9
8.5
1.0
1.2
mmol/l
0.19
76
517
157
1164
1.43
3.78
3.4
2.9
2.4
2.4
mmol/l
0.19
136
1030
131
941
1.47
3.73
3.3
2.3
2.3
2.4
g/l
0.45
126
871
235
1869
1.36
3.73
2.4
2.0
256.7
250.6
u/l
0.03
219
1759
92
616
1.55
3.65
2.2
2.3
34.2
34.1
u/l
0.01
80
518
122
868
1.48
3.65
3.4
2.4
21.8
22.9
%
0.39
108
749
766
7293
1.63
3.64
12.6
9.6
24.8
25.7
u/l
0.87
746
7054
313
2614
1.32
3.53
2.0
1.9
95.8
94.9
pmol/l
0.14
167
1383
137
1007
1.43
3.45
2.0
1.8
—
—
—
0
0
157
1184
1.40
3.43
4.1
3.6
401.6
429.5
ng/l
0.05
116
857
196
1535
1.36
3.40
1.5
1.5
20.7
20.9
nmol/l
0.05
178
1298
690
6457
1.40
3.33
19.2
13.8
39.6
39.9
%
0.55
526
4826
6
7
8.62
3.26
3.2
3.4
—
—
—
0
0
252
2063
1.32
3.22
3.0
2.4
70.8
55.7
u/l
0.67
237
1907
733
6944
1.47
3.20
19.7
14.5
139.7
139.6
mmol/l
0.13
718
6760
685
6423
1.38
3.09
5.3
4.7
1.9
2.1
mu/l
0.49
649
5922
7
12
5.87
3.02
1.0
1.6
—
—
—
0
0
7
12
5.87
3.02
1.4
1.8
—
—
—
0
0
733
6964
1.44
2.95
20.0
14.6
3.9
4.0
mmol/l
0.38
718
6763
31
163
1.94
2.93
4.8
4.0
29.1
48.0
mg/l
0.50
23
131
31
163
1.94
2.93
4.8
4.0
69.3
96.4
mg/l
0.27
23
129
70
465
1.55
2.91
1.5
1.3
172.3
213.7
u/ml
0.21
63
428
437
3889
1.26
2.78
5.2
4.7
6.4
6.6
mmol/l
1.10
409
3587
17
72
2.39
2.74
1.0
1.1
—
—
—
0
0
47
288
1.67
2.72
1.4
2.2
38.8
40.4
u/l
0.19
42
257
42
250
1.72
2.70
1.5
1.8
—
—
—
0
0
30
161
1.90
2.69
4.9
4.0
—
2.1
—
0
19
693
6548
1.35
2.66
4.6
4.2
5.8
5.8
mmol/l
0.68
654
6001
12
43
2.82
2.65
3.1
3.0
—
—
—
0
0
33
185
1.82
2.60
8.7
4.5
1.8
1.5
mg/l
1.03
33
167
124
943
1.37
2.57
3.2
3.0
0.6
0.8
ug/l
1.84
91
621
200
1641
1.29
2.45
2.8
2.2
—
—
—
0
0
24
124
1.96
2.42
1.9
1.4
121.6
109.7
u/ml
—
7
24
45
283
1.62
2.39
3.3
3.5
60.6
48.3
%
2.38
45
278
70
487
1.48
2.39
2.3
2.3
41.7
18.4
au/ml
—
5
23
20
97
2.09
2.39
2.1
2.9
4.4
46.7
u/ml
0.51
20
90
162
1302
1.30
2.32
4.9
4.5
23.6
21.4
%
1.13
84
630
35
208
1.71
2.30
2.0
2.6
2.9
3.1
g/l
0.87
30
166
7
18
3.91
2.25
1.1
1.3
—
—
—
0
0
10
36
2.80
2.20
1.3
2.0
—
—
—
0
0
10
36
2.80
2.20
1.3
2.0
—
—
—
0
0
10
36
2.80
2.20
1.5
1.3
15.8
14.3
u/l
—
10
31
53
771
0.67
2.18
4.5
4.2
34.3
32.0
%
0.71
36
517
27
151
1.81
2.18
1.1
1.2
73.5
36.5
u/ml
—
5
15
22
115
1.94
2.17
1.2
1.5
—
—
—
0
0
61
423
1.48
2.13
2.5
2.1
12.8
11.7
nmol/l
0.36
52
377
36
221
1.66
2.12
2.0
2.5
6.9
7.3
g/l
0.56
30
173
36
221
1.66
2.12
2.0
2.5
—
—
—
0
0
36
221
1.66
2.12
2.0
2.5
3.6
3.7
g/l
0.46
29
165
71
510
1.43
2.08
2.3
2.6
58.9
68.5
ml/min/173m2
1.14
31
217
44
286
1.57
2.07
1.3
1.3
291.4
245.9
miu/ml
0.33
23
141
32
194
1.68
1.99
2.3
2.8
1.2
0.8
g/l
0.23
27
176
32
194
1.68
1.99
1.5
1.6
—
177.5
—
0
8
13
57
2.30
1.98
1.1
1.2
—
—
—
0
0
44
291
1.54
1.94
3.2
3.1
24.9
25.1
mmol/l
0.17
44
282
6
16
3.77
1.93
1.3
1.0
—
—
—
0
0
305
2687
1.21
1.93
4.1
3.6
—
—
—
0
0
7
22
3.20
1.88
1.4
1.2
—
—
—
0
0
11
46
2.41
1.85
1.5
1.2
—
—
—
0
0
20
110
1.84
1.74
1.3
1.2
—
—
—
0
0
196
1667
1.23
1.74
1.3
1.3
0.8
1.8
u/ml
1.47
57
449
7
24
2.93
1.72
1.3
2.6
88.6
85.1
ug/l
—
7
24
18
318
0.56
1.70
1.3
1.8
4.9
3.2
mg/l
0.25
11
228
203
1738
1.22
1.69
1.7
1.6
1.3
1.4
mmol/l
0.97
172
1457
15
76
1.99
1.65
1.0
1.1
—
—
—
0
0
7
27
2.61
1.51
1.1
1.1
—
—
—
0
0
28
178
1.59
1.50
5.8
3.9
3.8
3.9
mmol/l
0.32
28
163
15
79
1.92
1.50
1.0
1.1
—
—
—
0
0
693
6667
1.24
1.50
4.5
4.1
4.6
4.7
mmol/l
0.32
655
6205
9
38
2.38
1.46
1.1
1.1
—
—
—
0
0
690
6640
1.23
1.45
4.3
4.1
1.5
1.5
mmol/l
0.20
649
6152
66
502
1.34
1.44
2.8
2.4
10.7
6.4
ug/l
0.28
60
446
215
1882
1.19
1.41
4.5
3.8
0.0
0.0
estimate
1.08
75
692
7
29
2.43
1.39
1.0
1.0
—
—
—
0
0
95
765
1.27
1.38
8.6
6.6
—
—
—
0
0
703
6788
1.23
1.37
5.0
4.5
2.7
2.8
mmol/l
0.82
659
6283
9
41
2.21
1.37
1.6
1.4
—
22.5
—
0
6
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
41
2.21
1.37
1.1
1.2
—
—
—
0
0
24
151
1.61
1.36
1.3
1.3
—
—
—
0
0
189
1641
1.20
1.35
6.0
5.1
2.2
3.3
ug/l
0.93
173
1465
14
75
1.88
1.35
1.2
1.1
55.0
61.8
u/l
—
7
51
28
184
1.54
1.33
1.3
1.1
—
—
—
0
0
15
83
1.82
1.32
1.7
1.7
—
—
—
0
0
27
177
1.54
1.30
1.3
1.2
—
—
—
0
0
18
106
1.71
1.30
1.1
1.1
—
—
—
0
0
31
210
1.49
1.29
1.1
1.2
—
—
—
0
0
25
162
1.56
1.27
1.6
1.6
34.0
40.6
nmol/l
1.13
25
155
160
1377
1.20
1.26
1.5
1.4
—
—
—
0
0
172
1491
1.19
1.26
3.8
3.8
1.0
1.0
kg/l
0.01
18
190
31
212
1.48
1.24
1.1
1.2
—
—
—
0
0
77
613
1.28
1.24
2.9
4.3
26.5
25.3
ug/l
0.02
59
506
60
462
1.32
1.23
2.9
3.3
4.4
4.6
pmol/l
0.89
54
409
194
1703
1.18
1.23
3.3
3.1
1295.4
1206.9
ng/l
0.12
160
1448
143
1222
1.21
1.22
1.3
1.3
21.5
30.4
iu/ml
1.10
41
385
8
37
2.17
1.21
1.1
1.0
—
—
—
0
0
14
78
1.81
1.21
1.1
1.7
—
—
—
0
0
51
666
0.75
1.19
1.5
1.6
—
—
—
0
0
34
241
1.43
1.15
1.3
1.3
—
—
—
0
0
54
414
1.33
1.15
1.1
1.0
—
—
—
0
0
22
142
1.56
1.15
1.5
1.7
—
—
—
0
0
662
6387
1.18
1.13
4.0
3.7
1.3
1.3
mmol/l
0.01
617
5896
11
58
1.91
1.12
1.5
1.8
—
—
—
0
0
8
40
2.01
1.12
1.1
1.3
—
—
—
0
0
33
235
1.42
1.10
1.3
1.4
10.4
10.1
u/l
0.05
25
189
170
1490
1.18
1.10
1.6
1.6
—
—
—
0
0
352
3256
1.14
1.09
3.2
2.8
129.3
107.4
ug/l
0.41
332
3024
26
178
1.48
1.06
1.3
1.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
26
178
1.48
1.06
4.7
2.9
0.3
0.4
u/ml
1.12
17
90
195
1734
1.16
1.06
2.6
2.1
2.7
3.0
mg/l
1.08
170
1480
67
538
1.27
1.03
1.8
1.7
—
—
—
0
0
12
68
1.78
1.01
1.5
1.6
—
—
—
0
0
23
157
1.48
0.97
1.3
1.3
—
—
—
0
0
30
217
1.40
0.94
5.8
4.1
1.3
1.4
mmol/l
0.20
30
212
6
27
2.23
0.93
1.3
1.5
15.0
13.3
pmol/l
—
6
22
6
28
2.15
0.91
3.7
1.7
21.7
33.0
umol/l
—
6
28
32
236
1.37
0.91
3.7
3.5
99.3
1327.2
u/ml
0.99
23
205
6
29
2.08
0.89
1.2
1.4
—
—
—
0
0
6
29
2.08
0.89
1.5
2.6
—
—
—
0
0
81
680
1.21
0.87
2.0
1.8
—
—
—
0
0
8
44
1.83
0.86
1.4
1.5
0.8
1.0
g/l
—
8
44
21
147
1.44
0.80
1.8
1.7
—
—
—
0
0
16
106
1.52
0.79
2.1
1.7
—
—
—
0
0
16
106
1.52
0.79
1.1
1.6
—
—
—
0
0
6
33
1.82
0.79
1.2
3.2
574.2
816.0
u/ml
—
6
33
25
182
1.39
0.78
1.4
1.2
4.0
11.3
u/ml
—
6
30
49
395
1.26
0.77
1.3
1.4
21.5
26.6
iu/l
0.67
42
329
19
132
1.45
0.76
1.6
1.4
—
—
—
0
0
19
132
1.45
0.76
1.6
1.4
—
—
—
0
0
9
53
1.71
0.75
1.0
1.0
—
—
—
0
0
628
6095
1.12
0.75
5.7
5.4
38.5
39.3
mmol/mol
1.60
592
5672
9
54
1.67
0.74
1.1
1.1
—
—
—
0
0
25
184
1.37
0.74
1.5
1.2
—
—
—
0
0
21
150
1.41
0.74
1.7
1.7
—
—
—
0
0
7
38
1.85
0.73
2.7
3.3
—
—
—
0
0
9
56
1.61
0.72
1.3
1.6
—
—
—
0
0
9
56
1.61
0.72
1.3
1.6
—
—
—
0
0
9
56
1.61
0.72
1.2
1.0
—
—
—
0
0
9
56
1.61
0.72
1.3
1.6
—
—
—
0
0
10
60
1.67
0.72
3.8
2.5
—
—
—
0
0
202
1854
1.12
0.69
4.3
4.1
14.8
8.7
mg/mmol
0.52
124
1167
657
6404
1.12
0.69
15.9
11.8
82.6
84.4
ml/min/173m2
1.11
538
5210
5
27
1.86
0.68
1.2
1.4
—
—
—
0
0
9
59
1.53
0.68
1.2
1.3
—
—
—
0
0
5
28
1.79
0.66
1.4
2.0
—
—
—
0
0
36
286
1.27
0.66
1.3
1.5
—
—
—
0
0
10
62
1.62
0.65
5.1
3.5
—
—
—
0
0
14
95
1.48
0.64
1.1
1.6
—
—
—
0
0
5
29
1.73
0.64
1.4
2.0
—
—
—
0
0
21
155
1.36
0.63
1.1
1.1
0.6
2.0
u/ml
—
8
61
12
79
1.53
0.63
1.2
1.6
—
—
—
0
0
20
147
1.37
0.62
1.6
1.3
—
—
—
0
0
25
191
1.32
0.61
1.2
1.8
3.3
5.6
iu/l
—
8
65
123
1365
0.88
0.61
1.6
1.7
440.5
29921687.5
pmol/l
1.57
100
1143
8
52
1.54
0.59
1.0
1.4
—
—
—
0
0
83
727
1.16
0.59
26.9
20.6
1.2
1.2
inr
0.18
11
105
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
6
36
1.67
0.56
1.0
1.3
—
21.7
—
0
6
6
36
1.67
0.56
1.0
1.1
—
—
—
0
0
6
37
1.63
0.55
1.3
1.8
—
—
—
0
0
9
60
1.51
0.54
1.2
1.3
—
—
—
0
0
9
61
1.48
0.54
1.3
1.5
—
—
—
0
0
9
62
1.46
0.53
1.7
1.5
1.3
1.4
nmol/l
—
9
55
14
100
1.41
0.52
1.0
1.1
—
—
—
0
0
210
1966
1.09
0.50
3.7
3.1
6.9
7.6
mmol/l
1.61
175
1651
24
189
1.28
0.50
2.1
3.0
—
—
—
0
0
10
67
1.50
0.50
1.0
1.1
—
—
—
0
0
10
67
1.50
0.50
1.9
1.8
—
—
—
0
0
10
67
1.50
0.50
1.0
1.1
—
—
—
0
0
7
45
1.56
0.49
1.6
1.9
—
—
—
0
0
10
68
1.48
0.47
1.0
1.1
—
—
—
0
0
10
68
1.48
0.47
1.0
1.1
—
—
—
0
0
10
68
1.48
0.47
1.0
1.1
—
—
—
0
0
59
515
1.16
0.46
6.8
3.8
1.2
1.2
mmol/l
0.72
50
443
47
403
1.18
0.46
1.2
1.3
—
—
—
0
0
7
51
1.38
0.44
1.3
1.5
—
—
—
0
0
9
127
0.71
0.43
1.2
1.9
0.6
0.9
nmol/l
—
9
105
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
471
4572
1.07
0.42
3.3
3.0
45.9
44.0
u/l
0.18
445
4295
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
128
1186
1.09
0.39
1.3
1.3
14.1
9.4
u/ml
0.37
46
469
107
1156
0.91
0.36
1.6
1.7
1267.9
1188.5
nmol/l
0.39
81
864
5
79
0.63
0.35
1.0
1.2
—
—
—
0
0
6
42
1.43
0.35
1.0
1.0
34.3
31.4
u/l
—
6
31
6
42
1.43
0.35
1.0
1.0
80.8
97.4
u/l
—
6
31
10
73
1.37
0.34
1.0
1.2
—
—
—
0
0
14
109
1.29
0.33
1.1
1.1
—
—
—
0
0
6
46
1.31
0.33
1.2
1.2
—
—
—
0
0
17
207
0.82
0.30
1.2
1.5
—
—
—
0
0
17
139
1.23
0.29
1.4
1.6
—
—
—
0
0
33
290
1.14
0.27
1.6
1.8
—
—
—
0
0
18
150
1.20
0.26
4.2
2.5
80.1
117.1
ug/min
—
10
93
42
377
1.12
0.26
1.5
1.4
—
—
—
0
0
15
123
1.22
0.25
1.3
1.2
—
—
—
0
0
9
73
1.24
0.25
4.7
3.5
29.9
58.8
u/ml
—
9
73
17
142
1.20
0.24
1.8
1.3
287.9
243.7
u/ml
0.16
12
83
40
360
1.12
0.24
2.1
1.6
—
—
—
0
0
43
389
1.11
0.24
4.9
3.8
0.9
1.6
mmol/l
0.65
33
293
11
88
1.25
0.22
1.5
1.3
—
—
—
0
0
20
172
1.17
0.22
1.9
1.6
—
—
—
0
0
5
42
1.19
0.21
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
14
117
1.20
0.20
1.1
1.1
—
11.5
—
0
9
0
14
0.00
0.20
0.0
1.0
—
24.2
—
0
14
110
1155
0.95
0.20
2.2
2.2
—
—
—
0
0
11
90
1.23
0.19
1.5
1.3
—
—
—
0
0
11
90
1.23
0.19
1.5
1.3
—
—
—
0
0
54
580
0.93
0.18
1.4
1.2
52.2
166.7
iu/ml
5.19
18
228
7
58
1.21
0.18
1.4
1.8
—
—
—
0
0
7
63
1.11
0.17
1.9
1.3
—
—
—
0
0
69
655
1.06
0.14
3.8
3.2
—
—
—
0
0
7
88
0.79
0.14
1.0
1.1
1.4
1.5
g/l
—
7
79
22
243
0.90
0.14
1.6
1.7
—
—
—
0
0
55
581
0.94
0.13
1.4
1.5
—
—
—
0
0
82
855
0.95
0.13
1.7
1.7
1.5
1.4
%
0.15
76
763
43
404
1.07
0.12
1.8
2.2
3816.2
4503.0
u/l
0.09
16
165
243
2385
1.03
0.11
3.5
3.5
33.3
52.7
ng/l
0.59
153
1539
11
126
0.87
0.11
1.5
1.7
—
—
—
0
0
40
378
1.06
0.10
1.4
1.4
—
—
—
0
0
29
271
1.07
0.10
1.3
1.6
—
—
—
0
0
5
45
1.11
0.10
1.4
1.8
—
—
—
0
0
15
135
1.11
0.09
1.3
1.4
—
—
—
0
0
36
340
1.06
0.09
1.4
1.5
—
—
—
0
0
16
146
1.10
0.08
2.2
2.4
128.8
129.5
g/l
0.04
11
109
20
185
1.08
0.08
1.8
1.4
309.9
307.3
ug/g
0.03
14
101
10
88
1.14
0.08
1.6
1.3
—
—
—
0
0
10
88
1.14
0.08
1.6
1.3
—
—
—
0
0
14
127
1.10
0.08
3.5
2.5
16.1
16.1
%
—
7
64
7
68
1.03
0.08
2.1
2.0
20.7
24.4
nmol/l
—
7
63
18
167
1.08
0.07
3.5
3.2
8.9
8.3
kpa
0.68
18
154
10
89
1.13
0.07
1.6
1.3
—
—
—
0
0
9
105
0.86
0.06
2.6
2.0
12.9
13.2
%
—
9
105
31
297
1.05
0.05
1.6
1.7
—
—
—
0
0
103
1045
0.98
0.03
2.0
2.0
—
—
—
0
0
14
149
0.94
0.03
1.1
1.1
—
—
—
0
0
24
247
0.97
0.01
2.8
1.9
—
—
—
0
0
32
315
1.02
0.00
1.3
1.4
—
—
—
0
0
32
316
1.01
0.00
1.4
1.4
—
—
—
0
0
32
316
1.01
0.00
1.3
1.4
—
—
—
0
0
32
317
1.01
0.00
1.4
1.4
—
—
—
0
0
23
228
1.01
0.00
1.5
2.0
—
—
—
0
0
10
105
0.95
0.00
1.1
1.1
—
—
—
0
0
12
115
1.04
0.00
1.2
1.0
0.7
2.0
u/ml
—
7
54
0
5
0.00
0.00
0.0
1.0
—
65.2
—
0
5
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
8
86
0.93
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
9
91
0.99
0.00
1.6
1.3
1.0
0.5
nmol/l
—
9
84
8
85
0.94
0.00
1.1
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
7.0
—
0
7
23
230
1.00
0.00
2.7
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
5
51
0.98
0.00
1.0
1.4
274372.0
127002.3
e6/l
—
5
37
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC_UPPERLIMB and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_UPPERLIMB | 0.956 [0.77, 1.18] | 0.675 |
| Birth year | 0.993 [0.98, 1.0] | 0.108 |
During the follow-up period (1.1.1998 — 31.12.2019), 141 out of 2628 females with CD2_BENIGN_MELANOCYTIC_UPPERLIMB died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_UPPERLIMB | 1.079 [0.87, 1.33] | 0.484 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 195 out of 1808 males with CD2_BENIGN_MELANOCYTIC_UPPERLIMB died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC_UPPERLIMB.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.078% | 0.197% |
| 5 | 0.423% | 1.251% |
| 10 | 1.2% | 3.089% |
| 15 | 2.353% | 6.013% |
| 20 | 4.284% | 10.315% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC_UPPERLIMB – Melanocytic naevi of upper limb, including shoulder
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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