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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Left side

Z21_LEFT_SIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 ZB0.0
  • Cause of death: ICD-10 ZB0.0

2 out of 7 registries used, show all original rules.

144

4. Check minimum number of events

None

144

5. Include endpoints

None

144

6. Filter based on genotype QC (FinnGen only)

137

Control definitions (FinnGen only)

Control exclude
Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z[AB]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 137 68 69
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 69.29 70.81 67.78

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
144
Matched controls
1440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZB0.0
ICD-10 Finland
Left side
+∞
202.1
142
*
WX111
NOMESCO Finland
Local infiltration anesthesia
27.9
75.5
59
35
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
21.3
56.4
48
33
M17.1
ICD-10 Finland
Other primary gonarthrosis
10.6
44.7
99
248
SPAT1212
SPAT
Extensive examination of musculoskeletal system
11.8
40.3
50
62
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
10.4
36.5
50
70
Z50.1
ICD-10 Finland
Other physical therapy
12.2
34.7
40
44
M16.1
ICD-10 Finland
Other primary coxarthrosis
7.9
32.8
63
129
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
9.3
32.7
49
76
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
7.7
30.3
57
113
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
6.6
24.9
53
117
B01AB10
ATC
tinzaparin; parenteral
5.9
19.3
43
97
ZB0.1
ICD-10 Finland
Right side
+∞
19.2
18
*
R4135
NOMESCO Finland
Rehabilitation for hearing problems
17.1
14.1
22
15
WX320
NOMESCO Finland
Spinalanesthesy
3.8
14.1
68
273
U07.2
ICD-10 Finland
COVID-19, virus not identified
4.8
14.0
38
100
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
5.1
14.0
35
86
B01AF01
ATC
rivaroxaban; oral
4.4
13.9
45
136
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
6.7
13.7
24
42
B01AB05
ATC
enoxaparin; parenteral
3.7
13.4
80
366
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
4.0
13.0
48
159
Z3231
NOMESCO Finland
Registered nurse
3.4
11.8
68
299
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.7
10.9
45
159
ZXD10
NOMESCO Finland
Scheduled procedure
0.1
10.7
8
413
E66.01
ICD-10 Finland
Obesity due to excess calories
5.2
10.7
24
53
TPH04
NOMESCO Finland
Cathetrisation of vein
3.3
10.1
54
223
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
3.7
9.2
35
116
N02BE01
ATC
paracetamol; systemic, rectal
15.0
8.5
142
1189
M01AH05
ATC
etoricoxib; oral
3.1
8.5
108
703
XQ845
NOMESCO Finland
Dermatoscopy
13.0
7.2
12
10
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
8.2
7.1
15
20
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.6
6.5
53
266
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.7
6.5
46
216
RTGKO, ,
NOMESCO Finland
+∞
6.3
6
*
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.5
6.2
58
309
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
3.3
6.2
25
85
A10BA02
ATC
metformin; oral
2.5
6.1
57
303
M01AX05
ATC
glucosamine; oral
2.5
6.1
49
243
R74
ICPC
Upper respiratory infection acute
0.2
6.1
5
254
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.8
6.0
36
154

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
98
44
67.59
146.95
4.6
6.3
—
—
—
0
0
104
68
52.46
133.79
5.1
5.0
—
—
—
0
0
76
33
47.65
112.82
3.6
4.4
7.26
7.03
mmol/l
0.20
76
33
76
34
46.22
111.58
3.6
4.4
1.53
1.41
mmol/l
0.48
76
34
50
24
31.38
69.49
1.9
3.5
105.92
106.37
mmol/l
0.20
50
24
50
24
31.38
69.49
1.9
3.5
—
—
—
0
0
50
24
31.38
69.49
1.9
3.5
4.11
3.97
mmol/l
1.08
50
24
136
406
43.20
57.37
6.9
4.2
—
—
—
0
0
78
122
12.77
54.20
4.1
4.4
2.28
1.87
mmol/l
0.54
66
99
119
368
13.87
44.17
6.2
3.8
—
—
—
0
0
50
71
10.26
36.05
1.9
2.8
0.76
0.64
%
1.53
50
71
78
220
6.55
28.75
2.0
3.3
3.94
2.65
e6/l
0.41
78
118
131
598
14.19
28.70
3.5
2.9
—
—
—
0
0
108
425
7.16
27.04
5.7
3.4
—
—
—
0
0
28
31
10.97
23.78
5.2
5.4
29.82
27.66
mg/l
0.10
22
19
46
102
6.16
21.20
3.9
5.5
0.14
0.21
%
—
7
38
125
644
8.13
20.87
12.9
5.5
0.00
0.00
estimate
—
6
129
125
650
8.00
20.47
6.8
4.1
0.00
0.00
estimate
-0.00
27
139
125
652
7.95
20.33
6.8
4.1
0.00
0.00
estimate
—
6
122
39
81
6.23
19.10
5.2
2.4
—
—
—
0
0
46
113
5.51
18.76
3.9
5.2
2.06
1.10
%
—
8
49
91
419
4.18
15.82
4.2
3.3
—
—
—
0
0
45
128
4.66
15.13
2.6
4.7
1.23
1.22
mmol/l
0.69
45
108
86
393
3.95
14.85
2.5
3.4
0.14
0.43
e6/l
2.41
86
293
75
324
3.74
13.85
1.4
1.4
—
—
—
0
0
52
178
4.01
13.49
3.5
7.1
105.73
103.38
mmol/l
3.49
52
178
86
418
3.63
13.02
2.1
2.8
—
—
—
0
0
95
549
3.15
9.80
4.3
4.1
31.49
40.52
ng/l
0.45
81
404
96
583
2.94
8.61
6.9
6.4
58.06
57.91
%
0.04
91
549
144
1269
+∞
7.28
24.9
15.5
—
—
—
0
0
57
290
2.60
6.87
1.9
1.8
1.05
1.46
mg/l
0.77
51
227
89
559
2.55
6.84
5.7
6.4
0.57
0.67
%
1.14
83
526
8
317
0.21
6.63
1.4
7.4
—
—
—
0
0
90
576
2.50
6.53
5.6
6.5
3.21
2.68
%
1.37
84
541
144
1288
+∞
6.44
20.6
18.8
140.38
139.63
mmol/l
4.02
144
1255
90
579
2.48
6.41
5.7
7.0
8.54
8.71
%
0.23
84
547
144
1293
+∞
6.24
20.4
18.9
4.04
3.99
mmol/l
1.80
144
1258
55
290
2.45
6.02
1.6
1.9
352.68
452.68
pmol/l
3.42
47
235
144
1305
+∞
5.63
25.1
19.5
79.54
80.21
umol/l
0.11
144
1305
85
566
2.22
5.16
4.3
4.7
36.53
35.14
g/l
1.55
85
531
114
878
2.43
4.60
6.2
4.5
—
—
—
0
0
56
828
0.47
4.57
4.9
4.7
—
245.06
—
0
17
22
83
2.95
4.57
2.7
2.6
—
—
—
0
0
20
436
0.37
4.28
2.0
3.3
2.38
2.35
mmol/l
0.61
20
377
39
206
2.22
4.06
3.5
2.0
—
—
—
0
0
19
71
2.93
4.01
1.2
1.3
—
—
—
0
0
144
1344
+∞
3.83
32.2
24.1
134.14
135.52
g/l
0.54
144
1322
144
1344
+∞
3.83
31.9
23.9
4.46
4.48
e12/l
0.23
144
1302
144
1344
+∞
3.83
31.7
24.0
28.60
40.17
%
10.93
138
1263
144
1344
+∞
3.83
31.8
23.9
90.62
91.44
fl
1.46
144
1324
144
1344
+∞
3.83
32.0
23.9
7.21
6.71
e9/l
1.14
144
1304
144
1343
+∞
3.82
31.8
23.8
30.18
30.43
pg
1.07
144
1323
144
1343
+∞
3.82
31.9
23.9
263.69
244.54
e9/l
2.07
144
1309
29
513
0.46
3.57
2.9
2.1
—
—
—
0
0
0
82
0.00
3.26
0.0
1.2
—
—
—
0
0
29
150
2.17
3.13
2.7
1.7
—
—
—
0
0
6
184
0.30
2.94
1.0
1.3
—
—
—
0
0
9
22
4.29
2.93
1.2
2.4
—
—
—
0
0
0
65
0.00
2.49
0.0
3.8
—
—
—
0
0
14
290
0.43
2.45
4.4
2.9
2.63
4.17
e6/l
1.17
14
264
83
652
1.64
2.22
16.6
13.1
1.35
1.27
inr
0.21
20
197
6
14
4.42
2.17
1.2
1.4
—
—
—
0
0
35
222
1.76
2.08
1.6
1.3
91.90
38.54
iu/ml
—
10
73
23
371
0.55
1.89
5.4
3.4
—
—
—
0
0
75
592
1.56
1.85
7.2
7.1
—
—
—
0
0
17
297
0.52
1.81
6.4
3.9
—
—
—
0
0
0
46
0.00
1.74
0.0
1.4
—
—
—
0
0
0
48
0.00
1.73
0.0
3.3
—
—
—
0
0
0
49
0.00
1.72
0.0
1.3
—
—
—
0
0
8
168
0.45
1.60
1.9
1.3
—
—
—
0
0
5
128
0.37
1.59
1.6
2.4
0.24
0.22
g/l
—
5
118
66
522
1.49
1.53
2.0
2.0
86.73
95.77
pmol/l
1.05
42
257
31
209
1.62
1.46
1.4
1.3
1.89
10.91
u/ml
1.67
22
75
0
37
0.00
1.36
0.0
6.1
—
1.33
—
0
32
5
18
2.84
1.29
1.2
1.2
—
—
—
0
0
48
380
1.39
1.04
5.2
4.5
—
—
—
0
0
0
29
0.00
0.99
0.0
2.7
—
—
—
0
0
0
30
0.00
0.98
0.0
1.2
—
—
—
0
0
14
85
1.72
0.98
1.1
1.3
—
—
—
0
0
7
127
0.53
0.93
7.3
4.2
—
—
—
0
0
16
233
0.65
0.85
1.3
1.5
3.45
2.87
g/l
0.44
16
144
0
26
0.00
0.79
0.0
1.2
—
—
—
0
0
0
26
0.00
0.79
0.0
2.3
—
—
—
0
0
0
27
0.00
0.78
0.0
1.5
—
—
—
0
0
16
110
1.51
0.72
1.7
2.1
328.81
363.78
nmol/l
0.31
16
97
7
116
0.58
0.71
1.4
1.5
—
—
—
0
0
5
28
1.81
0.67
3.4
3.2
—
—
—
0
0
6
103
0.56
0.65
7.0
3.0
175.67
213.52
ng/l
—
6
93
6
104
0.56
0.64
1.5
2.9
10.38
10.15
g/l
—
6
90
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
0
20
0.00
0.61
0.0
1.9
—
—
—
0
0
0
20
0.00
0.61
0.0
3.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
2.0
—
89.45
—
0
21
0
23
0.00
0.59
0.0
2.2
—
60.45
—
0
23
0
23
0.00
0.59
0.0
1.1
—
—
—
0
0
6
35
1.74
0.58
2.0
1.6
—
—
—
0
0
5
88
0.55
0.58
1.2
1.8
0.82
1.63
g/l
—
5
78
8
125
0.62
0.57
1.4
1.3
—
—
—
0
0
9
63
1.46
0.53
1.1
1.2
—
—
—
0
0
8
119
0.65
0.48
1.5
1.4
—
—
—
0
0
20
249
0.77
0.45
1.2
1.2
0.92
0.82
u/ml
—
10
69
5
31
1.63
0.43
1.0
6.1
—
—
—
0
0
11
149
0.72
0.42
1.3
1.3
—
—
—
0
0
5
33
1.53
0.42
5.2
3.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
271.40
—
0
10
0
16
0.00
0.41
0.0
2.8
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
32.50
—
0
16
14
181
0.75
0.41
7.4
6.4
1.06
1.02
mmol/l
0.19
14
168
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
36820.50
—
0
10
0
17
0.00
0.41
0.0
3.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
4.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
3.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
8
104
0.76
0.22
1.0
2.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
3.0
—
51.83
—
0
6
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
113.46
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
35.15
—
0
12
0
12
0.00
0.21
0.0
2.0
—
10.91
—
0
12
0
12
0.00
0.21
0.0
1.2
—
39.14
—
0
7
0
12
0.00
0.21
0.0
13.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
244.38
—
0
8
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
43
398
1.11
0.19
2.4
3.4
106.24
63.67
mg/l
0.42
29
261
15
174
0.85
0.19
1.4
1.4
—
—
—
0
0
6
76
0.78
0.16
1.0
1.3
—
31.70
—
0
5
5
47
1.07
0.09
1.0
4.6
68.10
47.53
mg/l
—
5
38
5
47
1.07
0.09
1.0
4.6
43.54
33.18
mg/l
—
5
38
13
144
0.89
0.09
2.2
3.3
11.46
7.91
umol/l
0.36
13
132
6
74
0.80
0.08
1.5
2.8
1.03
1.44
g/l
—
6
65
10
112
0.88
0.07
1.8
1.4
—
—
—
0
0
10
111
0.89
0.06
3.6
8.7
—
—
—
0
0
23
218
1.07
0.05
2.9
1.8
27.82
29.45
s
1.38
23
211
91
922
0.96
0.04
3.6
4.2
—
—
—
0
0
29
282
1.04
0.02
4.9
4.5
1.02
1.02
kg/l
0.24
19
39
12
113
1.07
0.02
3.1
3.9
99.00
82.10
ng/l
—
6
99
12
127
0.94
0.01
1.5
2.8
69.33
66.32
g/l
0.81
12
120
0
6
0.00
0.00
0.0
2.2
—
1.19
—
0
6
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
10.28
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
32.43
—
0
7
5
56
0.89
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.0
—
8.49
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
151.40
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
201.13
—
0
8
0
7
0.00
-0.00
0.0
1.6
—
20.96
—
0
7
0
8
0.00
-0.00
0.0
2.9
—
4.26
—
0
8
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_LEFT_SIDE – Left side

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).