Pneumonia due to Streptococcus pneumoniae

J10_PNEUMOPNEUMO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J13
  • Hospital discharge: ICD-9 481
  • Hospital discharge: ICD-8 48199
  • Cause of death: ICD-10 J13
  • Cause of death: ICD-9 481
  • Cause of death: ICD-8 48199

2 out of 7 registries used, show all original rules.

1691

4. Check minimum number of events

None

1691

5. Include endpoints

None

1691

6. Filter based on genotype QC (FinnGen only)

1691

Control definitions (FinnGen only)

Control exclude
J10_INFLUPNEU

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J09-J18
Name in latin
Pneumonia a Streptococco pneumoniae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 18491 7292 10991
Only index persons 14115 5899 8216
Unadjusted period prevalence (%)
Whole population 0.27 0.21 0.31
Only index persons 0.27 0.22 0.31
Median age at first event (years)
Whole population 50.75 54.75 47.87
Only index persons 44.56 49.26 41.19

-FinnGen-

Key figures

All Female Male
Number of individuals 1691 707 984
Unadjusted period prevalence (%) 0.35 0.24 0.43
Median age at first event (years) 54.66 52.46 56.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1515
Matched controls
15148
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
216.0
323.0
433
28
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
4503599627370496.0
323.0
1120
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
68.5
323.0
911
326
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
633.7
323.0
383
8
48199
ICD-8 Finland
Pneumococcal pneumonia
+∞
224.7
210
*
4810A
ICD-9 Finland
Pneumococcal pneumonia[PNEUMONIA PNEUMOCOCCICA]
+∞
195.1
183
*
J01MA14
ATC
moxifloxacin; systemic
9.0
125.5
286
383
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.4
86.5
360
1000
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
80.4
756
3890
R03BB04
ATC
tiotropium bromide; inhalant
5.6
80.4
256
530
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
5.4
79.7
264
572
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
12.5
79.3
147
129
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.6
76.9
413
1421
J01MA12
ATC
levofloxacin; systemic
3.8
76.1
386
1265
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.3
75.2
319
891
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
+∞
70.4
67
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.7
68.3
348
1133
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
341.5
66.0
66
*
H02AB06
ATC
prednisolone; systemic
2.5
61.9
756
4302
R81
ICPC
Pneumonia
13.6
61.5
109
86
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.7
58.6
181
355
J45.9
ICD-10 Finland
Asthma, unspecified
3.3
57.1
333
1187
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
61.3
50.8
59
10
J86.9
ICD-10 Finland
Pyothorax without fistula
81.6
49.2
55
7
R03AC02
ATC
salbutamol; inhalant
2.2
48.8
784
4900
48609
ICD-8 Finland
Pneumonia, unspecified
+∞
46.1
44
*
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
6.3
43.1
119
201
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
6.2
43.1
121
209
A41.9
ICD-10 Finland
Sepsis, unspecified
7.0
42.6
109
166
C03CA01
ATC
furosemide; systemic
2.4
42.2
470
2421
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
40.9
746
4793
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.7
40.2
194
585
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
8.8
40.2
88
105
R50.9
ICD-10 Finland
Fever, unspecified
3.0
39.9
254
940
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
38.6
260
1000
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.3
37.9
121
244
J01FA06
ATC
roxithromycin; oral
2.1
37.8
614
3717
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.3
37.6
103
172
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
36.9
167
476
J45.1
ICD-10 Finland
Nonallergic asthma
4.4
36.2
137
331
J47
ICD-10 Finland
Bronchiectasis
15.1
34.2
57
39
R06.0
ICD-10 Finland
Dyspnoea
2.3
33.8
381
1935
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
122.8
33.8
36
*
J46
ICD-10 Finland
Status asthmaticus
7.8
33.3
78
104
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
+∞
32.4
31
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.3
32.1
178
594
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.6
31.0
150
451
J01CA04
ATC
amoxicillin; systemic
2.0
30.6
1154
9306
R03DA04
ATC
theophylline; systemic, rectal
4.1
30.6
126
330
J01FF01
ATC
clindamycin; systemic
2.1
30.1
426
2382
I50.9
ICD-10 Finland
Heart failure, unspecified
2.6
28.1
220
915
J15.8
ICD-10 Finland
Other bacterial pneumonia
286.6
27.8
28
*
R03BA05
ATC
fluticasone; inhalant
2.3
27.6
279
1331
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.6
27.0
129
383
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.5
27.0
131
394
J96.1
ICD-10 Finland
Chronic respiratory failure
9.3
26.8
56
62
J96.0
ICD-10 Finland
Acute respiratory failure
16.0
26.0
42
27
GD1AD
NOMESCO Finland
Thorax CT examination
5.1
25.7
83
170
48509
ICD-8 Finland
Bronchopneumonia, unspecified
+∞
25.1
24
*
R03BA01
ATC
beclometasone; inhalant
2.5
25.0
216
946
TGC00
NOMESCO Finland
Bronchial lavation
7.0
24.5
61
90
R96
ICPC
Asthma
3.1
23.7
137
469
R03DC03
ATC
montelukast; oral
2.4
23.7
228
1052
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
23.4
168
663
A03
ICPC
Fever
2.3
23.0
233
1106
J01AA02
ATC
doxycycline; systemic
1.8
22.8
1083
8863
WX892
NOMESCO Finland
Monitored bed care
3.0
22.7
135
472
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
22.7
305
1643
SPAT1263
SPAT
Sampling
1.8
22.4
587
4004
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
3.4
22.3
111
341
H02AB07
ATC
prednisone; oral
2.3
22.1
216
1007
R03AC12
ATC
salmeterol; inhalant
4.1
22.0
89
229
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.6
22.0
102
296
R02
ICPC
Shortness of breath/dyspnoea
2.6
21.9
175
733
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.5
21.8
65
122
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
116.7
21.6
23
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.4
21.5
79
186
R03BB01
ATC
ipratropium bromide; inhalant
4.1
21.4
85
216
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
19.2
21.3
32
17
WX730
NOMESCO Finland
Conventional respirator
7.6
21.3
50
68
R95
ICPC
Chron obstructive pulmonary disease
6.4
20.9
55
88
0382A
ICD-9 Finland
Septicaemia, Pneumococcal septicaemia
+∞
20.9
20
*
ZX120
NOMESCO Finland
Intravenous
2.7
20.5
147
578
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
10.0
20.1
40
41
H02AB04
ATC
methylprednisolone; systemic
2.2
20.0
214
1037
R03AK07
ATC
formoterol and budesonide; inhalant
2.1
20.0
265
1408
J01DA01
ATC
[U] cefalexin; systemic
1.6
18.6
860
6766
I50.0
ICD-10 Finland
Congestive heart failure
2.9
18.6
118
431
J80
ICD-10 Finland
Adult respiratory distress syndrome
44.6
18.3
22
5
J45.8
ICD-10 Finland
Mixed asthma
5.0
18.3
59
122
WX872
NOMESCO Finland
Intensive care
3.4
18.1
91
282
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
18.1
548
3836
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
18.1
194
941
A46
ICD-10 Finland
Erysipelas
2.2
17.9
206
1029
WW200
NOMESCO Finland
Immunization
4.5
17.6
63
145
N05AA02
ATC
levomepromazine; systemic
3.8
17.4
75
205
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.6
17.4
79
226
J45
ICD-10 Finland
Asthma
2.5
17.0
138
580
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
16.9
387
2489
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
+∞
16.7
16
*
R03BA02
ATC
budesonide; inhalant
2.0
16.6
234
1270
WX725
NOMESCO Finland
Noninvasive ventilation
3.5
16.5
78
231
J01FA09
ATC
clarithromycin; systemic
1.7
16.5
404
2647
J20
ICD-10 Finland
Acute bronchitis
2.5
16.5
135
570
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
16.1
383
2486
N02AA05
ATC
oxycodone; systemic
2.1
16.1
199
1023
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
16.0
269
1559
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
33.7
15.7
20
6
C90.0
ICD-10 Finland
Multiple myeloma
7.9
15.6
35
45
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
15.5
175
866
49300
ICD-8 Finland
Asthma, bronchiale
4.7
15.5
53
117
SPAT1255
SPAT
Intravenous administration of medicine
2.8
15.5
104
394
N05BA01
ATC
diazepam; systemic, rectal
2.1
15.4
184
933
WX882
NOMESCO Finland
High dependency care
4.6
15.3
53
119
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.0
15.2
60
153
R03AC13
ATC
formoterol; inhalant
3.0
15.1
88
305
N05CD07
ATC
temazepam; oral
2.1
14.9
185
954
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
6.1
14.9
40
67
R05
ICPC
Cough
1.8
14.8
284
1713
SPAT1262
SPAT
Handing over of treatment supplies
1.8
14.7
260
1532
J01FA15
ATC
telithromycin; oral
2.3
14.5
145
680
120
Kela drug reimbursment
Hypogammaglobulinaemia
151.4
14.5
15
*
J18.8
ICD-10 Finland
Other pneumonia, organism unspecified
151.4
14.5
15
*
N03AX16
ATC
pregabalin; oral
1.8
14.5
292
1791
R04.2
ICD-10 Finland
Haemoptysis
4.0
14.4
58
151
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.3
14.2
53
128
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
6.1
14.1
38
64
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
4.5
14.1
49
111
C07AB07
ATC
bisoprolol; oral
1.5
13.8
618
4691
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.0
13.8
55
142
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
141.2
13.5
14
*
J86.00
ICD-10 Finland
Empyema with broncho-pleural fistula
141.2
13.5
14
*
N05CF01
ATC
zopiclone; oral
1.6
13.5
423
2942
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
6.5
13.4
34
53
153
Kela drug reimbursment
Lenalidomid
18.4
13.4
20
11
SPAT1254
SPAT
Administration of medicine
1.9
13.3
197
1086
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.3
13.3
124
562
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.5
13.1
46
105
N05AH04
ATC
quetiapine; oral
1.9
13.0
206
1163
A07AA02
ATC
nystatin; oral
2.7
12.8
88
338
XG410
NOMESCO Finland
Flow-volume spirometry
3.1
12.7
69
229
J12.8
ICD-10 Finland
Other viral pneumonia
70.5
12.6
14
*
N06AX11
ATC
mirtazapine; oral
1.6
12.5
385
2653
M04AA01
ATC
allopurinol; systemic
1.9
12.5
186
1027
J01DB01
ATC
cefalexin; oral
1.5
12.3
1107
9679
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
12.3
398
2776
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.6
12.3
35
64
N02AX02
ATC
tramadol; systemic, rectal
1.5
12.2
548
4130
JN4AD
NOMESCO Finland
Body CT examination
2.4
12.2
106
465
N05BA04
ATC
oxazepam; oral
1.7
12.1
301
1961
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
12.0
204
1179
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
12.0
143
723
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
10.1
12.0
23
23
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.7
11.9
39
84
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
6.7
11.7
29
44
L04AX04
ATC
lenalidomide; oral
16.5
11.7
18
11
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.5
11.7
40
90
R06AE07
ATC
cetirizine; oral
1.5
11.7
535
4039
A02BC02
ATC
pantoprazole; systemic
1.5
11.6
824
6808
AA1AD
NOMESCO Finland
CT of head and brain
1.7
11.6
299
1964
J12.9
ICD-10 Finland
Viral pneumonia, unspecified
+∞
11.5
11
*
R03AK08
ATC
formoterol and beclometasone; inhalant
3.4
11.4
55
168
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
5.6
11.3
32
58
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
11.3
215
1289
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
8.4
11.3
24
29
J43.9
ICD-10 Finland
Emphysema, unspecified
6.0
11.2
30
51
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.6
11.2
38
85
N03AX12
ATC
gabapentin; oral
1.8
11.2
188
1082
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.7
11.1
77
298
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
10.9
179
1019
H02AB09
ATC
hydrocortisone; systemic
4.2
10.9
40
97
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.1
10.8
59
197
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
10.8
83
342
J01MA02
ATC
ciprofloxacin; systemic
1.5
10.8
497
3739
R03AC03
ATC
terbutaline; inhalant
1.9
10.7
168
944
C03DA01
ATC
spironolactone; oral
2.0
10.6
143
758
N06AA09
ATC
amitriptyline; systemic
2.1
10.6
120
594
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.9
10.6
63
223
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
7.0
10.6
25
36
N05AH03
ATC
olanzapine; systemic
2.5
10.6
79
321
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
10.5
572
4447
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
10.5
911
7757
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
10.4
366
2589
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.2
10.3
53
170
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.7
10.3
70
269
N05BA06
ATC
lorazepam; systemic, sublingual
2.6
10.3
74
294
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
10.3
66
246
A06AD11
ATC
lactulose; oral
1.8
10.2
192
1147
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
10.2
268
1764
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.6
10.2
327
2264
A10AE04
ATC
insulin glargine; parenteral
2.0
10.1
131
683
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
10.1
160
901
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
5.4
10.0
29
55
GBB00
NOMESCO Finland
Tracheostomy
5.8
10.0
27
47
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
5.8
10.0
27
47
B18.2
ICD-10 Finland
Chronic viral hepatitis C
5.6
10.0
28
51
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.3
9.9
48
148
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
6.0
9.8
26
44
C01AA05
ATC
digoxin; systemic
2.1
9.8
118
598
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
10.7
9.8
18
17
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.5
9.8
44
128
JN4BD
NOMESCO Finland
Extensive body CT
2.0
9.8
133
711
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.2
9.7
50
161
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
9.7
286
1933
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.8
9.7
61
223
GAC46
NOMESCO Finland
Partial decortication of pleura
55.3
9.7
11
*
XW000
NOMESCO Finland
Bone marrow biopsy
2.8
9.6
60
217
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
6.9
9.6
23
34
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
9.6
113
570
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
9.6
300
2061
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
4.7
9.5
31
67
A41.8
ICD-10 Finland
Other specified sepsis
4.6
9.4
31
68
A02BC01
ATC
omeprazole; systemic
1.5
9.4
345
2459
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
9.4
337
2391
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.2
9.3
99
476
S97
ICPC
Chronic ulcer skin
2.5
9.3
73
304
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.9
9.2
55
197
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
7.8
9.1
20
26
JN3AD
NOMESCO Finland
Abdominal CT examination
2.1
9.1
98
475
N02BE01
ATC
paracetamol; systemic, rectal
1.4
9.1
1131
10153
348
Kela drug reimbursment
Roflumilast
36.9
9.0
11
*
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.3
9.0
32
76
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
4.1
9.0
33
81
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
7.5
8.9
20
27
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
24.2
8.9
12
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
8.8
194
1215
N06AB04
ATC
citalopram; systemic
1.6
8.8
245
1632
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
8.8
91
434
N03AG01
ATC
valproic acid; systemic, rectal
2.4
8.7
75
327
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.8
8.7
55
202
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
3.4
8.7
40
119
XG466
NOMESCO Finland
Sleep oxymetry
3.0
8.7
47
158
J85.1
ICD-10 Finland
Abscess of lung with pneumonia
50.3
8.7
10
*
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.1
8.7
32
79
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
5.5
8.6
24
44
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.3
8.6
41
126
N03AE01
ATC
clonazepam; systemic
2.4
8.6
71
303
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
4.8
8.6
27
57
A02BC03
ATC
lansoprazole; oral
1.5
8.5
343
2487
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
8.5
77
347
J01FA10
ATC
azithromycin; systemic
1.4
8.5
699
5801
A40.9
ICD-10 Finland
Streptococcal sepsis, unspecified
20.1
8.5
12
6
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
4.4
8.4
29
67
TKC20
NOMESCO Finland
Catheterisation of bladder
2.1
8.4
97
486
TK810
NOMESCO Finland
Hemofiltration
8.6
8.3
17
20
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
5.5
8.3
23
42
F05.9
ICD-10 Finland
Delirium, unspecified
4.2
8.3
30
73
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.2
8.3
41
130
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
8.2
334
2426
WX704
NOMESCO Finland
Intubation
2.1
8.2
89
434
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
8.1
120
662
C09AA05
ATC
ramipril; oral
1.5
8.1
308
2205
SPAT1260
SPAT
Consultation of another employee
1.6
8.1
213
1399
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
8.2
8.1
17
21
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
33.5
8.1
10
*
R03DX07
ATC
roflumilast; oral
33.5
8.1
10
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.9
8.1
31
80
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.0
8.0
107
566
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.2
8.0
83
396
SPAT1301
SPAT
No procedures
1.4
8.0
392
2953
I50.1
ICD-10 Finland
Left ventricular failure
2.3
8.0
70
310
W19
ICD-10 Finland
Unspecified fall
1.9
7.9
116
637
F10.24
ICD-10 Finland
Alcohol depence active use
4.2
7.9
28
67
127
Kela drug reimbursment
Transplant complication
5.0
7.9
24
49
B01AB05
ATC
enoxaparin; parenteral
1.5
7.9
343
2523
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.5
7.8
58
236
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
5.7
7.8
21
37
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
7.8
77
360
J18
ICD-10 Finland
Pneumonia, organism unspecified
9.5
7.8
15
16
J98.1
ICD-10 Finland
Pulmonary collapse
9.5
7.8
15
16
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
7.0
7.8
18
26
B01AA03
ATC
warfarin; systemic
1.5
7.8
251
1732
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.8
7.7
46
165
R03AK11
ATC
formoterol and fluticasone; inhalant
3.4
7.7
35
104
A28
ICPC
Limited function/disability NOS
1.7
7.7
161
990
N06AB03
ATC
fluoxetine; oral
1.8
7.7
134
779
N17.8
ICD-10 Finland
Other acute renal failure
5.6
7.7
21
38
Z72.0
ICD-10 Finland
Tobacco use
3.4
7.6
35
105
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
11.9
7.6
13
11
N06AX21
ATC
duloxetine; oral
1.8
7.5
118
667
M05BA04
ATC
alendronic acid; oral
2.0
7.4
90
459
L04AX01
ATC
azathioprine; systemic
2.5
7.4
55
224
WX722
NOMESCO Finland
PEEP
2.3
7.4
69
314
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.0
7.4
88
447
E86
ICD-10 Finland
Volume depletion
3.4
7.3
33
98
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
+∞
7.3
7
*
48601
ICD-8 Finland
More specifically, unspecified pneumonia and the pleural irritation caused by it
+∞
7.3
7
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
7.2
137
823
ZX108
NOMESCO Finland
Inhalation
7.3
7.2
16
22
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.5
7.2
54
223
L04AA01
ATC
[U] ciclosporin; systemic
4.4
7.2
24
55
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.1
313
2301
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
7.1
124
726
N07BB01
ATC
disulfiram; oral
2.4
7.1
59
256
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.7
7.1
46
175
A04AA01
ATC
ondansetron; systemic, rectal
2.1
7.0
72
346
N06AB05
ATC
paroxetine; oral
2.3
7.0
64
291
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.6
7.0
46
177
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
5.2
6.9
20
39
UGC02
NOMESCO Finland
Rigid bronchoscopy
13.8
6.9
11
8
N05AB01
ATC
dixyrazine; systemic
4.8
6.8
21
44
R03AC18
ATC
indacaterol; inhalant
8.3
6.8
14
17
R05FB02
ATC
cough suppressants and expectorants
1.4
6.8
455
3607
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
6.8
128
764
R06.2
ICD-10 Finland
Wheezing
2.4
6.8
55
237
G00.1
ICD-10 Finland
Pneumococcal meningitis
40.2
6.8
8
*
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
16.8
6.7
10
6
A02BA02
ATC
ranitidine; systemic
1.5
6.7
247
1749
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
4.1
6.7
24
59
F10.25
ICD-10 Finland
Alcohol dependence continuous use
3.6
6.7
28
79
N06AA12
ATC
doxepin; systemic
2.2
6.6
64
298
C08CA01
ATC
amlodipine; oral
1.4
6.6
423
3326
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.3
6.6
61
277
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
12.3
6.6
11
9
J01FA01
ATC
erythromycin; systemic
1.6
6.6
161
1035
J96.9
ICD-10 Finland
Respiratory failure, unspecified
8.7
6.6
13
15
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.6
6.6
46
182
R29
ICPC
Respiratory symptom/complaint other
2.1
6.5
73
363
N05AX12
ATC
aripiprazole; systemic
2.7
6.5
42
159
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
6.5
122
731
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
4.5
6.5
21
47
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.9
6.5
87
465
C01DA14
ATC
isosorbide mononitrate; oral
1.5
6.4
208
1434
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.9
6.4
94
517
N07BA03
ATC
varenicline; oral
2.2
6.4
62
289
R03
ICPC
Wheezing
4.9
6.4
19
39
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.3
6.3
54
238
N05BA02
ATC
chlordiazepoxide; systemic
2.8
6.3
37
133
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
6.3
76
392
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
9.3
6.3
12
13
6BA02
NOMESCO Finland
NA
9.3
6.3
12
13
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
18.1
6.3
9
5
4829X
ICD-9 Finland
Other bacterial pneumonia, Bacterial pneumonia unspecified
+∞
6.3
6
*
J15.1
ICD-10 Finland
Pneumonia due to Pseudomonas
+∞
6.3
6
*
J15.4
ICD-10 Finland
Pneumonia due to other streptococci
+∞
6.3
6
*
47099
ICD-8 Finland
Influenza, unqualified
+∞
6.3
6
*
WX726
NOMESCO Finland
High-flow oxygen therapy
+∞
6.3
6
*
N06AX03
ATC
mianserin; oral
2.3
6.2
56
252
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.3
6.2
21
49
TK800
NOMESCO Finland
Hemodialysis
3.2
6.2
30
95
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
6.2
73
371
R74
ICPC
Upper respiratory infection acute
1.4
6.2
301
2253
D70.82
ICD-10 Finland
Drug-induced neutropenia
4.1
6.2
22
54
N06AX16
ATC
venlafaxine; oral
1.6
6.2
142
899
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
3.7
6.2
25
69
M10.9
ICD-10 Finland
Gout, unspecified
1.9
6.2
79
417
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
5.8
6.1
16
28
N05AX08
ATC
risperidone; systemic
1.9
6.1
92
511
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.0
6.1
72
366
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
2.9
6.1
35
122
D07AA02
ATC
hydrocortisone; topical
1.6
6.1
164
1083
L04AD01
ATC
ciclosporin; systemic
3.6
6.1
25
70
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
12.6
6.1
10
8
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
6.1
211
1479
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
6.1
340
2610
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
6.0
121
736
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.0
406
3214
N05CD02
ATC
nitrazepam; oral
3.2
6.0
29
92
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
6.0
65
320

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
763
2868
4.03
169.66
6.0
3.6
—
—
—
0
0
103
30
36.50
164.18
1.2
1.0
—
—
—
0
0
102
87
12.41
101.28
3.2
1.9
—
—
—
0
0
169
382
4.80
70.25
2.3
1.7
3.9
2.4
ug/l
0.69
152
324
80
84
9.95
68.78
1.6
1.3
—
—
—
0
0
80
84
9.95
68.78
1.7
1.3
—
—
—
0
0
80
84
9.95
68.78
1.7
1.3
—
—
—
0
0
80
84
9.95
68.78
1.7
1.3
—
—
—
0
0
338
1254
3.12
68.42
8.7
7.4
1.4
0.7
mmol/l
2.04
267
961
337
1253
3.11
67.92
8.5
7.4
10.6
12.9
kpa
12.70
315
1204
337
1253
3.11
67.92
8.5
7.4
5.0
5.1
kpa
0.15
315
1204
312
1139
3.13
64.68
8.9
7.8
94.0
96.2
%
6.04
292
1104
246
825
3.32
58.43
4.7
2.4
11.1
10.8
g/l
0.31
219
757
221
705
3.46
56.79
6.4
5.2
—
—
—
0
0
276
1061
2.91
51.47
5.1
3.3
5.8
5.8
kpa
0.25
271
1033
273
1052
2.90
50.64
5.1
3.3
2.2
1.7
mmol/l
1.40
226
809
208
716
3.17
46.90
10.0
7.1
24.3
24.2
mmol/l
0.09
189
668
267
1060
2.80
46.62
9.6
8.1
120.8
122.5
g/l
0.55
254
1024
921
6220
2.06
45.22
8.4
5.8
11.4
12.1
umol/l
0.60
881
5896
248
982
2.79
43.35
7.7
6.7
1.7
1.4
mmol/l
1.57
239
949
188
652
3.12
41.70
2.2
1.7
1.1
1.3
g/l
1.62
166
602
652
3979
2.04
41.37
8.5
5.2
—
—
—
0
0
233
922
2.77
40.66
9.5
8.1
—
—
—
0
0
72
125
5.97
39.94
3.1
2.3
—
—
—
0
0
894
6164
1.96
39.28
8.8
5.3
1.9
2.0
e9/l
0.28
819
5413
228
908
2.75
39.24
5.0
2.8
4.7
4.6
kpa
0.42
222
884
897
6201
1.95
39.00
9.0
5.4
0.2
0.2
e9/l
0.73
819
5425
62
96
6.67
38.48
1.5
1.2
8.4
6.8
g/l
0.70
41
65
62
96
6.67
38.48
1.5
1.2
—
—
—
0
0
62
96
6.67
38.48
1.5
1.2
0.3
0.4
g/l
0.57
43
64
62
96
6.67
38.48
1.5
1.2
2.1
2.9
g/l
2.35
42
66
869
5966
1.94
38.33
8.7
5.2
0.6
0.6
e9/l
6.42
775
5124
803
5371
1.94
38.28
10.4
5.5
1.2
1.2
mmol/l
4.41
745
4833
870
5991
1.93
37.87
8.8
5.2
0.0
0.0
e9/l
1.94
776
5150
318
1520
2.35
37.10
8.2
5.2
1.1
1.0
mmol/l
0.76
299
1408
848
5817
1.92
37.07
8.7
5.4
24.5
28.6
%
18.66
804
5397
829
5653
1.92
36.81
9.0
5.5
8.3
8.8
%
3.33
787
5263
359
1824
2.23
36.13
5.2
3.2
0.8
0.8
mmol/l
0.36
337
1707
820
5619
1.89
35.41
8.7
5.3
2.4
2.9
%
9.38
779
5199
833
5739
1.89
35.35
8.4
5.2
60.5
56.5
%
14.24
788
5347
854
5931
1.89
35.35
10.9
5.9
1.2
1.2
mmol/l
4.67
720
5015
329
1639
2.25
34.61
2.3
1.9
—
—
—
0
0
1001
7355
1.88
34.31
7.4
4.2
6.9
6.7
mmol/l
1.63
948
6846
961
6988
1.87
33.85
13.5
7.7
4.8
4.0
e9/l
11.47
861
6078
793
5440
1.86
33.53
8.7
5.4
0.6
0.7
%
3.02
747
5045
756
5117
1.86
33.29
6.5
4.6
33.7
36.0
g/l
19.32
706
4771
205
859
2.58
31.60
4.5
3.5
0.9
0.6
%
0.76
83
193
218
943
2.51
31.43
4.6
3.7
1.1
0.9
%
0.51
107
264
226
997
2.46
31.22
9.4
7.0
10.8
9.7
mmol/l
1.42
214
949
89
228
4.06
31.21
5.2
3.4
—
—
—
0
0
296
1477
2.22
30.72
9.6
6.4
103.6
104.7
mmol/l
3.65
289
1441
90
236
3.97
30.57
6.7
4.1
3.0
2.4
mmol/l
0.93
68
143
179
722
2.65
29.75
7.2
3.3
7.4
7.4
ph
1.81
30
88
304
1556
2.16
29.51
3.2
2.4
21.2
23.7
%
1.77
248
1343
179
730
2.62
29.08
7.2
3.3
5.2
5.1
kpa
1.27
164
676
319
1675
2.11
28.95
3.1
2.4
2.2
2.3
g/l
2.70
293
1543
336
1801
2.08
28.86
3.1
2.4
11.7
13.5
umol/l
3.85
307
1661
274
1359
2.21
28.73
2.2
1.6
—
—
—
0
0
72
170
4.38
28.10
2.7
3.1
2.9
1.4
%
0.86
64
138
96
280
3.57
27.96
6.7
3.8
7.4
7.4
ph
0.81
86
233
51
90
5.81
27.81
2.7
2.4
1.2
1.2
e9/l
0.07
33
45
203
898
2.43
27.75
4.6
3.7
0.2
0.1
%
0.52
99
238
574
3729
1.82
27.55
3.3
2.5
57.3
58.6
u/l
0.10
535
3444
150
585
2.72
26.58
11.5
10.8
—
—
—
0
0
203
915
2.38
26.57
4.4
2.3
67.3
66.9
g/l
0.27
178
825
529
3388
1.82
26.39
4.0
2.7
2059.8
1259.4
ng/l
3.03
458
2870
526
3365
1.82
26.33
3.6
2.9
—
—
—
0
0
144
553
2.75
26.28
10.3
9.7
24.4
23.9
mmol/l
0.78
133
518
141
539
2.76
25.96
3.6
2.4
0.7
0.7
%
0.24
136
518
379
2204
1.93
25.51
1.9
1.9
—
—
—
0
0
532
3445
1.79
25.40
5.8
3.6
7.4
7.4
ph
1.24
128
646
42
67
6.40
25.32
2.0
2.5
12.1
15.7
%
0.53
14
29
124
452
2.88
24.94
5.7
5.5
0.9
0.9
%
0.04
115
428
125
458
2.87
24.91
5.7
5.4
1.8
1.7
%
0.69
115
432
709
5008
1.72
24.77
12.5
8.5
1.3
1.2
inr
0.59
248
1464
77
213
3.74
24.25
1.8
1.6
—
—
—
0
0
187
849
2.35
24.00
4.8
3.8
0.0
0.5
%
0.64
83
203
663
4676
1.69
22.76
5.0
3.3
33.2
69.5
ng/l
2.07
492
3239
66
172
3.95
22.62
1.9
1.8
0.6
1.0
g/l
1.13
44
138
125
482
2.72
22.60
8.5
4.5
—
—
—
0
0
471
3064
1.74
21.50
2.6
2.1
3.1
2.9
mg/l
0.57
403
2594
162
725
2.37
21.43
12.3
9.0
92.4
94.4
%
4.57
162
719
165
764
2.29
20.15
4.5
2.1
—
—
—
0
0
156
706
2.33
20.09
1.7
1.2
186.7
201.2
u/ml
0.14
141
650
422
2710
1.74
19.94
7.0
4.0
—
—
—
0
0
122
496
2.57
19.83
2.1
1.7
1.7
1.5
g/l
1.92
102
430
193
960
2.14
19.75
3.4
2.5
68.8
68.6
e9/l
0.02
156
751
1007
8075
1.61
19.56
5.4
4.0
139.2
2018.0
e6/l
1.61
15
121
34
58
5.96
19.20
3.3
2.2
2.3
0.1
e9/l
0.59
34
58
241
1317
1.97
19.05
3.1
2.5
1.9
1.7
%
1.05
211
1158
75
239
3.24
19.04
7.1
8.2
12.1
11.3
mmol/l
0.85
67
218
75
240
3.22
18.91
7.1
8.1
104.6
105.8
mmol/l
0.94
67
219
34
59
5.86
18.87
2.4
3.0
48.1
40.4
%
—
8
18
93
340
2.84
18.60
7.0
6.7
1.5
1.3
mmol/l
0.74
84
297
74
241
3.17
18.13
6.6
2.8
—
—
—
0
0
198
1030
2.04
17.94
3.0
2.2
361.5
369.4
nmol/l
0.14
181
956
245
1373
1.92
17.93
1.7
1.3
—
—
—
0
0
66
202
3.36
17.88
3.4
2.5
—
—
—
0
0
1146
9596
1.60
17.57
11.0
6.7
83.4
78.2
u/l
2.46
1099
8977
124
538
2.41
17.54
5.7
3.6
24.1
23.9
mmol/l
0.37
109
481
46
112
4.19
17.30
1.4
1.5
34.2
30.8
g/l
0.76
38
105
89
331
2.78
17.25
6.5
2.6
52.2
47.4
mg/l
0.36
69
270
89
332
2.77
17.15
6.5
2.6
80.4
88.7
mg/l
0.05
69
272
75
255
3.03
17.09
1.4
1.1
—
—
—
0
0
79
277
2.94
17.05
3.6
2.8
25.4
24.4
mmol/l
1.07
72
241
25
35
7.24
16.97
2.4
2.3
—
—
—
0
0
25
35
7.24
16.97
2.4
2.3
11.9
7.1
%
0.56
25
35
69
226
3.14
16.76
3.8
2.2
15.5
16.6
%
1.24
36
118
95
373
2.64
16.58
8.0
4.0
3.9
3.9
mmol/l
0.48
89
347
46
116
4.05
16.52
3.3
3.3
—
—
—
0
0
367
2376
1.70
16.45
3.3
2.6
527.9
564.2
mosm/kgh2o
2.31
318
2010
42
100
4.28
16.27
1.3
1.4
21709.1
1554.0
e6/l
0.50
34
74
103
429
2.49
15.92
1.4
1.4
—
7.9
—
0
13
110
475
2.41
15.73
9.4
3.5
25.2
24.6
mmol/l
1.35
104
439
120
541
2.31
15.56
9.1
3.4
—
—
—
0
0
35
75
4.74
15.44
2.6
2.2
1056.6
650.2
e6/l
1.43
14
34
433
2970
1.62
15.34
9.5
6.0
—
—
—
0
0
14
10
14.11
15.05
1.4
1.5
—
—
—
0
0
177
942
1.98
14.98
3.7
2.6
238.7
188.5
ng/l
0.75
158
852
382
2557
1.64
14.88
3.0
2.4
5.7
4.7
e6/l
0.73
337
2244
96
400
2.48
14.84
2.8
2.1
547.4
427.1
ug/l
0.26
91
379
385
2588
1.63
14.73
2.1
1.7
1.4
1.2
mg/l
1.05
310
1913
474
3383
1.56
13.97
3.6
3.0
0.6
0.4
e6/l
1.18
375
2569
24
40
6.07
13.87
1.4
1.3
—
—
—
0
0
51
157
3.32
13.74
1.4
1.3
—
—
—
0
0
61
213
2.93
13.31
4.9
3.4
61.0
56.7
%
2.04
61
213
506
3696
1.53
13.30
3.7
3.1
39.0
68.6
e6/l
1.35
404
2859
232
1399
1.76
13.21
1.8
1.6
—
—
—
0
0
336
2240
1.62
13.13
2.0
1.7
1285.2
1173.0
nmol/l
1.28
264
1682
32
73
4.45
13.11
2.2
1.2
1.1
1.0
u/ml
0.02
16
28
64
232
2.83
13.06
3.5
3.2
32.6
35.6
umol/l
0.55
56
197
16
18
8.96
12.90
3.6
2.2
—
—
—
0
0
289
1867
1.66
12.77
2.5
2.1
30.0
29.6
s
0.57
281
1815
224
1352
1.76
12.70
3.8
2.7
9.4
8.8
umol/l
0.12
187
1179
41
116
3.60
12.58
6.8
7.4
11.2
11.5
mg/l
0.14
36
109
58
205
2.89
12.40
4.5
3.2
4.7
4.0
e9/l
0.87
58
205
608
4677
1.47
12.17
4.3
3.1
—
5.6
—
0
6
337
2294
1.59
11.98
4.7
3.4
662.5
477.0
ng/l
0.31
267
1788
497
3691
1.49
11.81
2.5
2.0
195.4
240.8
u/l
0.66
467
3462
454
3323
1.50
11.54
4.9
3.6
0.0
0.0
estimate
0.01
163
1110
694
5521
1.44
11.43
14.7
8.4
0.0
0.0
e9/l
0.12
582
4546
39
114
3.48
11.42
3.3
3.0
59.6
54.9
%
0.50
30
76
762
6167
1.43
11.41
4.5
3.4
0.0
0.0
estimate
0.80
163
1099
753
6090
1.43
11.28
4.6
3.3
0.0
0.0
estimate
0.00
170
1146
167
958
1.82
11.20
5.7
3.5
1.2
1.2
mmol/l
0.24
151
816
1009
8608
1.43
11.13
5.2
3.9
—
—
—
0
0
34
93
3.71
10.98
1.6
1.6
1.6
1.3
promille
0.58
25
74
74
315
2.41
10.97
1.7
1.4
0.2
0.2
g/l
0.23
65
301
752
6102
1.42
10.95
5.9
4.5
0.0
0.0
estimate
0.50
172
1160
59
227
2.66
10.79
2.7
2.1
127.7
133.2
g/l
0.83
48
180
448
3315
1.48
10.66
3.5
2.9
—
—
—
0
0
51
183
2.84
10.65
1.5
1.3
60.5
61.1
mmol/l
0.04
41
152
32
87
3.73
10.43
1.3
1.3
39073.0
124705.4
e6/l
0.68
23
58
75
329
2.34
10.41
1.7
1.4
1.2
1.2
g/l
0.50
69
311
30
78
3.90
10.41
1.6
1.3
—
—
—
0
0
18
30
6.05
10.40
1.6
1.3
—
—
—
0
0
560
4346
1.43
10.30
4.3
3.5
42.2
103.3
e6/l
2.23
424
3094
336
2359
1.53
10.26
1.9
1.4
2.3
2.4
g/l
0.86
225
1430
525
4032
1.44
10.20
4.1
3.0
2.3
2.4
mmol/l
0.89
473
3526
178
1078
1.73
9.91
2.8
2.3
0.2
0.2
g/l
1.34
159
1009
658
5282
1.40
9.89
3.6
2.7
202.3
129.7
ug/l
3.78
602
4854
235
1538
1.61
9.72
1.4
1.3
395.8
466.3
titre
0.42
48
304
268
1828
1.55
9.27
1.8
1.6
—
—
—
0
0
141
821
1.78
9.00
4.8
3.8
99.6
84.3
ng/l
0.96
119
715
24
59
4.11
8.99
4.6
2.1
7.4
7.4
ph
—
8
15
21
47
4.51
8.84
1.3
1.4
—
—
—
0
0
392
2919
1.45
8.80
1.8
1.5
19.7
20.4
nmol/l
0.43
346
2491
186
1178
1.65
8.75
1.7
1.3
—
—
—
0
0
66
298
2.26
8.62
2.5
2.0
9.9
11.2
mg/l
0.65
61
272
12
16
7.55
8.42
1.6
1.3
—
—
—
0
0
231
1569
1.55
8.10
19.2
24.2
1.3
1.3
inr
0.07
28
217
30
93
3.27
8.09
1.2
1.5
—
—
—
0
0
52
218
2.43
8.04
3.1
2.9
0.8
0.8
nmol/l
0.17
44
170
133
790
1.74
7.94
1.6
1.4
—
—
—
0
0
22
56
3.97
7.89
3.4
2.6
830.0
1357.8
u/ml
0.54
22
56
30
96
3.16
7.70
1.3
1.4
—
—
—
0
0
146
903
1.68
7.53
1.5
1.5
—
—
—
0
0
161
1024
1.63
7.45
5.1
3.2
—
—
—
0
0
1040
9244
1.32
7.09
5.7
3.6
17.2
10.9
mm/h
19.43
980
8510
397
3064
1.39
7.09
5.9
3.6
87.4
88.8
%
0.55
383
2990
110
645
1.75
6.89
1.4
1.2
—
—
—
0
0
610
5058
1.32
6.75
2.2
1.9
92.3
94.6
pmol/l
0.59
346
2681
162
1061
1.58
6.65
3.0
2.2
5.5
7.5
ug/l
1.47
137
933
1381
12862
1.40
6.61
27.6
11.6
36.9
22.8
mg/l
25.56
1221
9918
21
59
3.59
6.60
2.1
1.6
—
—
—
0
0
64
322
2.03
6.43
1.2
1.2
100.0
52.7
titre
—
5
26
30
108
2.81
6.33
3.0
1.9
—
—
—
0
0
413
3269
1.35
6.19
3.7
2.5
1635.3
6457.6
umol/l
2.66
366
2825
162
1079
1.55
6.19
5.2
3.4
—
—
—
0
0
62
314
2.01
6.13
3.9
3.2
—
—
—
0
0
277
2061
1.41
6.06
3.0
2.7
1.8
1.0
e6/l
1.61
172
1207
50
236
2.15
5.96
3.0
2.7
—
—
—
0
0
17
45
3.81
5.82
2.3
2.5
26.1
211.8
ug/l
0.48
17
37
338
2618
1.36
5.79
1.9
1.7
42804899.6
30645585.3
pmol/l
0.11
271
2170
63
332
1.93
5.59
1.3
1.3
—
1305.0
—
0
10
66
354
1.90
5.56
1.5
1.5
308.8
282.1
ug/g
0.43
32
209
40
178
2.28
5.51
1.5
1.6
—
—
—
0
0
420
3397
1.31
5.33
4.3
3.1
—
—
—
0
0
13
30
4.36
5.30
1.9
2.5
106.7
220.0
e6/l
—
6
10
351
2777
1.33
5.19
4.3
3.3
—
—
—
0
0
341
2693
1.33
5.10
4.9
3.6
1.0
1.0
kg/l
0.12
42
383
17
50
3.42
5.03
2.2
1.9
—
—
—
0
0
35
156
2.27
4.84
4.4
2.1
—
—
—
0
0
121
803
1.55
4.74
3.3
2.9
4.8
3.9
e9/l
2.67
94
628
285
2215
1.34
4.73
3.3
2.8
2.5
2.4
mmol/l
2.39
248
1949
52
276
1.91
4.58
1.4
1.3
—
5.4
—
0
5
11
25
4.42
4.56
1.6
1.2
—
—
—
0
0
9
11
8.22
4.56
2.0
1.6
—
—
—
0
0
61
343
1.81
4.50
3.8
2.7
—
—
—
0
0
68
396
1.75
4.46
1.3
1.2
0.3
0.5
u/ml
—
9
36
1163
10775
1.25
4.40
27.5
14.7
14.1
13.6
%
19.31
1142
10532
59
331
1.81
4.39
5.4
1.8
36.8
38.3
g/l
1.09
47
278
13
35
3.74
4.37
6.0
4.7
—
—
—
0
0
9
12
7.53
4.35
2.3
1.8
—
—
—
0
0
248
1922
1.34
4.18
3.3
2.9
2.6
1.9
e6/l
0.57
142
1076
20
75
2.69
3.99
1.1
1.0
—
—
—
0
0
402
4775
0.79
3.98
3.1
2.8
—
—
—
0
0
459
3882
1.25
3.93
4.9
3.9
17.4
7.2
mg/mmol
2.10
325
2504
472
4007
1.25
3.90
4.0
3.2
7.5
7.9
mmol/l
0.97
403
3368
20
77
2.62
3.81
1.4
1.1
—
—
—
0
0
70
432
1.65
3.76
4.4
3.8
0.5
0.3
g/l
1.18
34
180
11
30
3.68
3.64
1.0
1.2
—
—
—
0
0
435
3687
1.24
3.62
4.0
3.2
564.3
232.2
mg/l
0.73
300
2380
17
62
2.76
3.59
1.1
1.1
—
—
—
0
0
59
353
1.70
3.58
1.1
1.2
—
—
—
0
0
7
9
7.80
3.56
1.3
1.0
—
—
—
0
0
24
105
2.30
3.53
1.2
1.1
—
—
—
0
0
253
3136
0.77
3.51
2.5
3.0
0.8
0.8
ug/l
0.09
164
2015
1207
12735
0.82
3.38
4.4
4.3
1.4
1.4
mmol/l
1.37
1112
11736
38
203
1.89
3.36
1.3
1.6
—
—
—
0
0
12
37
3.26
3.34
1.0
1.0
—
—
—
0
0
14
48
2.93
3.30
1.4
4.4
72.6
115.9
umol/l
—
7
29
19
77
2.48
3.30
1.2
1.1
—
—
—
0
0
1219
12835
0.82
3.25
4.5
4.3
4.5
4.6
mmol/l
4.51
1125
11894
35
184
1.92
3.25
1.2
1.4
—
—
—
0
0
23
104
2.23
3.16
1.1
1.5
19.3
25.5
%
0.56
12
70
91
1300
0.68
3.15
1.3
1.3
—
—
—
0
0
39
215
1.83
3.15
4.5
3.1
—
—
—
0
0
42
237
1.79
3.15
1.7
1.4
—
—
—
0
0
421
3619
1.22
3.00
4.6
3.6
—
—
—
0
0
449
3888
1.21
2.97
3.5
2.2
—
—
—
0
0
154
1173
1.34
2.95
3.4
4.2
70.9
20.2
ug/l
0.45
127
966
11
35
3.16
2.93
1.2
1.1
—
—
—
0
0
1246
13055
0.83
2.93
4.9
4.8
2.6
2.7
mmol/l
5.30
1142
12022
8
17
4.72
2.92
1.8
1.0
—
—
—
0
0
8
17
4.72
2.92
1.8
1.0
—
—
—
0
0
8
17
4.72
2.92
1.8
1.0
—
—
—
0
0
14
52
2.71
2.89
1.6
1.6
—
—
—
0
0
64
415
1.56
2.88
14.8
9.3
—
—
—
0
0
247
2012
1.27
2.88
1.3
1.2
37.8
30.7
iu/ml
0.42
80
615
654
5876
1.18
2.86
5.9
3.8
—
—
—
0
0
1383
13260
1.24
2.86
28.9
14.0
139.0
139.7
mmol/l
19.20
1351
12884
47
283
1.68
2.84
1.5
1.7
19567.9
15099.3
e6/l
0.28
34
200
10
31
3.24
2.77
2.6
2.0
—
—
—
0
0
12
42
2.87
2.75
1.9
1.8
—
—
—
0
0
39
226
1.74
2.71
1.8
1.4
106.1
124.6
u/ml
—
8
44
1386
13311
1.23
2.71
28.6
14.1
4.0
4.0
mmol/l
0.00
1353
12909
27
139
1.96
2.70
1.3
1.6
71.8
66.1
%
0.31
13
92
51
319
1.62
2.68
7.1
4.4
1.6
1.5
mg/l
0.30
45
289
9
24
3.76
2.67
1.2
1.2
—
—
—
0
0
16
67
2.40
2.63
1.6
1.3
146.1
137.5
nmol/l
0.23
16
67
50
314
1.61
2.60
5.2
4.1
—
—
—
0
0
5
7
7.16
2.55
1.4
1.0
—
—
—
0
0
5
7
7.16
2.55
1.4
1.0
—
—
—
0
0
14
56
2.51
2.53
4.4
2.8
—
—
—
0
0
7
16
4.39
2.47
1.0
1.5
—
—
—
0
0
6
12
5.01
2.40
3.0
1.1
—
—
—
0
0
19
90
2.12
2.39
1.4
1.5
—
—
—
0
0
140
1088
1.31
2.38
2.6
2.5
37.8
84.3
u/l
0.54
114
950
60
405
1.50
2.31
3.4
2.2
—
—
—
0
0
10
35
2.87
2.30
1.1
1.0
—
—
—
0
0
33
193
1.72
2.27
1.1
1.1
—
—
—
0
0
20
99
2.03
2.26
3.4
3.3
—
—
—
0
0
17
79
2.16
2.25
1.2
1.1
—
—
—
0
0
5
9
5.57
2.21
1.8
1.0
—
—
—
0
0
229
1910
1.23
2.19
1.2
1.2
11.1
10.8
u/ml
0.03
73
728
13
55
2.37
2.12
3.2
1.7
—
—
—
0
0
15
68
2.22
2.11
1.1
1.1
1.1
1.1
ratio
—
6
23
17
331
0.51
2.11
1.1
1.2
—
—
—
0
0
55
375
1.48
2.05
2.6
2.3
748.8
3613.0
u/l
1.74
18
154
13
56
2.33
2.05
1.0
1.6
—
—
—
0
0
6
15
4.01
2.04
1.0
1.1
—
—
—
0
0
22
118
1.88
2.02
1.9
1.3
—
—
—
0
0
38
240
1.60
1.99
1.4
1.2
—
—
—
0
0
16
77
2.09
1.96
1.1
1.0
—
—
—
0
0
18
91
1.99
1.95
3.3
1.9
—
—
—
0
0
26
150
1.74
1.91
1.9
1.5
—
—
—
0
0
13
58
2.25
1.91
3.7
3.3
—
—
—
0
0
14
65
2.16
1.88
5.3
1.5
—
—
—
0
0
59
821
0.71
1.86
1.2
1.4
—
—
—
0
0
10
40
2.51
1.83
3.6
3.0
—
—
—
0
0
1182
12295
0.87
1.83
4.0
3.9
1.4
1.3
mmol/l
1.35
1084
11260
21
365
0.57
1.82
1.0
1.1
—
—
—
0
0
38
246
1.56
1.82
1.7
1.3
—
—
—
0
0
32
199
1.62
1.81
1.1
1.1
—
—
—
0
0
40
264
1.53
1.77
1.6
1.4
179.5
711.4
e6/l
0.45
34
217
40
264
1.53
1.77
1.6
1.4
42.1
14.1
e6/l
0.50
33
209
83
631
1.33
1.71
4.8
3.3
—
—
—
0
0
87
671
1.31
1.63
4.1
3.5
4.5
4.6
pmol/l
0.27
80
591
308
2714
1.16
1.63
1.3
1.2
0.6
1.4
u/ml
3.42
74
698
5
14
3.58
1.61
1.0
2.6
—
—
—
0
0
7
26
2.70
1.58
5.4
3.5
—
—
—
0
0
32
207
1.56
1.57
1.7
1.3
—
—
—
0
0
22
129
1.71
1.57
1.3
1.1
—
—
—
0
0
51
365
1.41
1.54
1.4
1.5
11.1
8.1
u/l
0.77
41
302
0
44
0.00
1.51
0.0
1.0
—
—
—
0
0
64
479
1.35
1.49
3.3
2.2
—
—
—
0
0
37
534
0.69
1.48
1.0
1.1
—
—
—
0
0
1211
12519
0.88
1.48
4.8
4.4
6.1
5.9
mmol/l
3.59
1107
11379
58
432
1.35
1.41
3.6
2.1
21.7
21.5
s
0.10
53
382
36
246
1.47
1.40
1.4
1.4
—
—
—
0
0
39
271
1.45
1.40
2.0
1.9
1.5
0.8
nmol/l
1.59
32
231
940
8959
1.11
1.37
4.6
3.6
—
—
—
0
0
17
97
1.76
1.35
2.0
1.5
—
—
—
0
0
6
24
2.51
1.30
2.0
2.0
—
—
—
0
0
192
1662
1.18
1.30
1.4
1.2
—
—
—
0
0
22
137
1.61
1.29
1.1
1.2
—
—
—
0
0
119
991
1.22
1.23
1.5
1.4
—
—
—
0
0
12
63
1.91
1.23
3.0
2.9
—
—
—
0
0
29
196
1.49
1.22
5.2
3.1
—
—
—
0
0
17
101
1.69
1.20
1.3
1.9
2.5
1.7
u/field
—
8
41
48
358
1.35
1.19
1.2
1.3
109.4
224.7
miu/ml
1.26
16
167
19
117
1.63
1.18
1.1
1.3
146606.3
108837.8
e6/l
0.09
12
80
45
600
0.74
1.17
1.6
1.6
—
—
—
0
0
32
223
1.44
1.17
1.4
1.3
219.5
246.8
u/ml
0.23
20
138
66
518
1.29
1.16
3.2
2.1
—
—
—
0
0
8
39
2.06
1.15
2.6
8.5
23.2
25.3
mmol/l
—
8
34
1391
13598
1.13
1.14
24.1
11.7
—
—
—
0
0
65
512
1.28
1.12
3.3
2.1
—
—
—
0
0
58
450
1.30
1.12
2.3
3.3
169.1
8890.4
u/ml
0.80
43
382
28
192
1.47
1.11
1.0
1.1
14.8
6.9
u/ml
0.60
14
93
10
51
1.97
1.11
3.6
14.9
—
—
—
0
0
5
21
2.38
1.09
1.2
1.9
7.7
15.8
umol/l
—
5
21
22
144
1.53
1.09
2.4
2.5
—
—
—
0
0
166
1445
1.16
1.07
2.5
2.4
172.3
138.1
ug/g
0.56
121
1137
989
9516
1.09
1.07
4.0
3.7
14.7
14.8
pmol/l
0.61
894
8597
30
211
1.43
1.06
1.2
1.1
—
—
—
0
0
66
525
1.27
1.06
3.2
2.1
—
—
—
0
0
19
121
1.58
1.05
2.4
2.1
—
—
—
0
0
7
33
2.13
1.05
2.6
1.7
—
—
—
0
0
7
34
2.06
1.03
3.9
2.2
—
—
—
0
0
135
1162
1.18
1.01
1.8
1.7
—
—
—
0
0
7
35
2.00
1.00
1.4
1.2
—
—
—
0
0
65
522
1.26
0.98
3.3
2.1
—
—
—
0
0
54
424
1.28
0.98
1.8
1.6
290.5
275.7
mu/l
0.13
47
391
17
108
1.58
0.96
1.3
1.1
—
—
—
0
0
54
426
1.28
0.95
1.3
1.4
30.6
24.7
iu/l
0.55
37
356
7
37
1.90
0.94
1.1
1.1
—
—
—
0
0
96
810
1.20
0.92
2.6
2.7
—
—
—
0
0
20
134
1.50
0.92
1.3
1.4
78.9
59.0
mu/l
0.25
15
121
29
211
1.38
0.88
1.2
1.1
—
—
—
0
0
500
5307
0.92
0.88
4.1
4.9
2.3
3.6
ug/l
0.93
447
4763
38
291
1.31
0.85
1.4
1.2
1.3
2.7
u/ml
—
6
25
137
1201
1.15
0.85
7.3
3.8
—
—
—
0
0
17
112
1.52
0.85
1.2
1.3
—
—
—
0
0
29
213
1.37
0.84
1.3
1.4
—
—
—
0
0
20
137
1.47
0.84
1.5
1.3
—
—
nmol/l
—
0
0
19
129
1.48
0.83
1.4
1.4
681.1
315.3
pmol/l
0.81
11
106
26
188
1.39
0.83
1.3
1.2
5.5
4.4
u/ml
—
10
79
24
171
1.41
0.83
1.1
1.1
—
10.0
—
0
12
126
1438
0.87
0.83
1.6
1.7
—
—
—
0
0
1137
11080
1.08
0.78
30.6
15.6
331.8
333.5
g/l
6.23
1127
10995
47
378
1.25
0.75
1.4
1.3
—
—
—
0
0
28
210
1.34
0.74
1.0
1.1
10.7
2.3
u/ml
0.56
13
81
7
38
1.85
0.73
1.6
1.7
—
—
—
0
0
5
25
2.00
0.72
1.0
1.1
—
—
—
0
0
1161
11875
0.93
0.72
6.6
5.5
41.2
39.6
mmol/mol
5.65
1074
11004
9
56
1.61
0.72
1.0
1.1
489.9
201.3
iu/ml
—
9
56
7
40
1.75
0.71
1.7
2.5
—
—
—
0
0
24
177
1.36
0.71
1.2
1.2
—
—
—
0
0
7
41
1.71
0.70
2.1
1.5
—
—
—
0
0
66
557
1.19
0.68
2.2
1.8
—
—
—
0
0
26
340
0.76
0.67
1.2
1.6
—
—
—
0
0
25
188
1.33
0.66
1.0
1.1
0.8
1.3
u/ml
—
9
78
17
237
0.71
0.66
1.5
1.4
—
—
—
0
0
17
237
0.71
0.66
1.5
1.4
—
—
—
0
0
16
111
1.45
0.66
1.1
1.1
—
—
—
0
0
20
146
1.37
0.63
1.1
1.0
3.7
4.7
u/ml
—
9
56
6
102
0.59
0.62
2.7
1.5
0.9
1.0
g/l
—
6
102
18
244
0.73
0.60
1.4
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
1.7
—
0
20
20
148
1.36
0.59
1.3
1.2
—
—
—
0
0
18
131
1.38
0.59
1.2
1.1
—
—
—
0
0
21
157
1.34
0.59
1.1
1.2
—
—
—
0
0
319
2999
1.08
0.58
3.2
2.2
—
—
—
0
0
21
158
1.33
0.57
1.0
1.0
30.9
2.6
u/ml
—
9
56
75
858
0.87
0.56
2.5
2.4
73.0
20.4
au/ml
—
5
49
1218
11967
1.06
0.54
24.4
12.9
39.2
40.3
%
3.56
797
8722
10
66
1.52
0.52
1.2
1.3
—
—
—
0
0
23
179
1.29
0.51
1.0
1.1
5.1
2.8
u/ml
—
10
45
1180
11596
1.06
0.49
4.8
4.4
1.9
2.0
mu/l
0.54
1076
10576
14
101
1.39
0.49
1.5
1.4
15.3
11.7
mmol/l
—
5
23
467
4859
0.95
0.46
1.9
2.1
—
—
—
0
0
5
31
1.61
0.43
4.4
7.3
—
—
—
0
0
106
966
1.10
0.42
1.2
1.2
—
—
—
0
0
10
70
1.43
0.41
1.0
1.1
—
9.2
—
0
18
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
24
195
1.23
0.40
1.2
1.2
—
—
—
0
0
36
306
1.18
0.40
3.2
2.3
153.7
112.3
ug/min
0.29
29
196
5
37
1.35
0.37
1.8
1.4
—
—
—
0
0
15
116
1.30
0.37
2.1
2.0
28.5
20.5
nmol/l
0.54
15
110
69
622
1.11
0.35
2.6
2.3
—
—
—
0
0
6
43
1.40
0.35
1.3
2.4
—
—
—
0
0
17
137
1.24
0.32
1.0
1.0
0.2
0.5
u/ml
—
6
36
348
3606
0.96
0.31
1.6
1.4
—
—
—
0
0
7
53
1.32
0.31
1.3
1.1
1256.3
1594.0
miu/ml
—
7
53
17
138
1.23
0.30
1.5
1.3
—
—
—
0
0
7
54
1.30
0.30
1.4
1.8
1.9
5.2
nmol/l
—
7
45
150
1590
0.94
0.30
1.2
1.3
—
—
—
0
0
18
148
1.22
0.29
2.3
2.7
—
—
—
0
0
126
1183
1.07
0.29
1.3
1.4
—
—
—
0
0
8
64
1.25
0.27
1.1
1.3
—
—
—
0
0
16
131
1.22
0.27
1.4
1.4
—
—
—
0
0
8
67
1.19
0.26
1.0
1.2
—
—
—
0
0
12
95
1.27
0.26
2.2
2.4
10.9
11.2
%
0.23
12
95
82
763
1.08
0.25
1.2
1.2
102.2
157.4
iu/ml
1.04
29
309
49
446
1.10
0.24
1.8
1.7
—
—
—
0
0
1450
14587
0.96
0.23
36.2
18.0
132.1
137.3
g/l
26.64
1427
14350
47
429
1.10
0.22
1.0
1.1
—
—
—
0
0
1450
14583
0.96
0.22
35.8
17.9
4.4
4.5
e12/l
21.39
1418
14149
1450
14581
0.96
0.21
35.7
17.8
30.3
30.4
pg
0.54
1429
14344
1450
14581
0.96
0.21
35.7
17.8
91.2
90.9
fl
1.77
1429
14345
0
10
0.00
0.21
0.0
2.9
—
—
—
0
0
131
1374
0.95
0.21
1.5
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.1
—
0
8
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
8.2
—
0
6
328
3370
0.97
0.21
1.7
1.6
1.5
1.4
mmol/l
0.46
269
2825
56
518
1.08
0.20
1.3
1.2
—
—
—
0
0
1451
14588
0.96
0.20
35.9
17.9
7.5
6.6
e9/l
16.11
1417
14153
15
127
1.18
0.19
1.9
2.0
—
—
—
0
0
1450
14573
0.96
0.19
35.9
17.9
253.9
245.4
e9/l
3.94
1419
14180
8
69
1.16
0.16
1.0
1.6
51.9
11.6
ug/l
—
8
58
32
292
1.10
0.16
1.8
1.9
3.6
4.8
iu/l
0.70
15
102
32
294
1.09
0.14
2.9
2.1
—
—
—
0
0
11
128
0.86
0.13
1.4
1.4
90.1
295.9
pmol/l
—
5
39
9
108
0.83
0.13
1.0
1.1
—
—
—
0
0
25
231
1.08
0.10
1.3
1.3
—
—
—
0
0
16
144
1.11
0.10
2.1
1.4
—
—
—
0
0
6
57
1.05
0.08
2.0
2.4
2.4
1.4
ug/l
—
6
52
46
477
0.96
0.06
2.0
1.8
37.5
39.0
nmol/l
0.24
46
459
121
1233
0.98
0.06
2.2
2.2
12.2
13.1
nmol/l
0.60
104
1096
53
514
1.03
0.05
3.1
2.7
—
—
—
0
0
13
120
1.08
0.05
1.5
1.8
—
—
—
0
0
81
796
1.02
0.03
1.1
1.3
—
—
—
0
0
1384
13827
1.01
0.02
15.0
9.3
27.4
27.6
u/l
0.15
1341
13308
59
583
1.01
0.01
1.1
1.1
—
126.8
titre
—
0
11
29
291
1.00
0.00
3.6
3.1
43.4
25.7
mg/l
1.37
23
178
12
122
0.98
0.00
1.6
1.5
—
—
—
0
0
10
98
1.02
0.00
1.1
1.1
260.0
380.7
nmol/l
—
5
87
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
7
76
0.92
0.00
2.7
7.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
10
100
1.00
0.00
1.4
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
2.7
—
0
5
0
6
0.00
0.00
0.0
1.2
—
13.6
—
0
6
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
7
75
0.93
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
1184.4
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint J10_PNEUMOPNEUMO and mortality.

Females

Parameter HR [95% CI] p-value
J10_PNEUMOPNEUMO 2.366 [2.04, 2.74] < 0.001
Birth year 0.994 [0.99, 1.0] 0.19

During the follow-up period (1.1.1998 — 31.12.2019), 1121 out of 4384 females with J10_PNEUMOPNEUMO died.

Males

Parameter HR [95% CI] p-value
J10_PNEUMOPNEUMO 2.825 [2.45, 3.26] < 0.001
Birth year 0.99 [0.98, 1.0] 0.031

During the follow-up period (1.1.1998 — 31.12.2019), 1720 out of 5802 males with J10_PNEUMOPNEUMO died.

Mortality risk

Mortality risk for people of age

years, who have J10_PNEUMOPNEUMO.

N-year risk Females Males
1 0.207% 0.591%
5 1.481% 3.573%
10 3.593% 8.349%
15 6.483% 15.976%
20 11.707% 25.92%

Relationships between endpoints

Index endpoint: J10_PNEUMOPNEUMO – Pneumonia due to Streptococcus pneumoniae

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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