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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Other operation for atrial fibrillation

AF_OPER_OTHER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Operations: NOMESCO codes ^FPD96

1 out of 7 registries used, show all original rules.

173

4. Check minimum number of events

None

173

5. Include endpoints

None

173

6. Filter based on genotype QC (FinnGen only)

173

Control definitions (FinnGen only)

Control exclude
AF_OPER

Extra metadata

First used in FinnGen datafreeze
DF4

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 173 37 136
Unadjusted period prevalence (%) 0.05 0.01 0.06
Median age at first event (years) 64.54 67.05 63.85

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
158
Matched controls
1580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
+∞
228.3
158
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
139.5
85.5
154
341
B01AA03
ATC
warfarin; systemic
68.8
82.5
149
305
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
24.2
55.4
85
72
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
+∞
52.0
47
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
32.4
49.1
66
34
I34.1
ICD-10 Finland
Mitral (valve) prolapse
50.0
46.9
56
17
TFP20
NOMESCO Finland
Cardiodefibrillation
16.1
46.2
85
106
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
10.6
37.5
89
170
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
9.7
36.9
99
232
WX872
NOMESCO Finland
Intensive care
17.5
34.6
57
49
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
95.5
34.6
37
5
AC4
HP
MVP
148.3
34.2
35
*
C01BD01
ATC
amiodarone; systemic
23.0
34.0
50
31
207
Kela drug reimbursment
Chronic arrhythmias
8.7
32.7
90
208
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
7.6
30.6
106
334
AH2
HP
Treatment of atrial fibrillation by maze surgery or its modification as the only procedure
+∞
30.1
28
*
C07AB07
ATC
bisoprolol; oral
11.0
29.4
142
705
AN1
HP
Coronary angiography
8.2
29.3
80
175
C01AA05
ATC
digoxin; systemic
10.7
28.7
61
87
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
26.7
28.2
39
19
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
51.4
28.0
33
8
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.8
24.9
127
592
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
25.0
24.3
34
17
AA1
HP
Conventional CABG
21.0
23.6
35
21
C03CA01
ATC
furosemide; systemic
5.5
22.2
102
393
WX408
NOMESCO Finland
General anesthesy, balanced
5.4
21.5
89
303
FFM10
NOMESCO Finland
Occlusion or excision of atrial appendage externally with a closing device
239.9
21.1
21
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
22.3
19.5
28
15
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
5.0
19.2
82
279
XF404
NOMESCO Finland
Ambulatory ECG
7.2
18.9
50
95
I50.9
ICD-10 Finland
Heart failure, unspecified
5.6
18.5
64
171
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
8.9
17.9
40
58
C01BC04
ATC
flecainide; systemic
11.3
17.2
33
36
K78
ICPC
Atrial fibrillation/flutter
6.1
16.1
48
105
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
8.5
15.9
36
53
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
8.5
15.9
36
53
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
35.6
15.2
19
6
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
9.1
14.5
31
41
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
5.7
14.4
45
103
AP1
HP
Catheterization of the left side of the heart
16.8
14.0
22
15
FKC60
NOMESCO Finland
Resection and reconstruction of leaflet of mitral valve for insufficiency
+∞
13.7
13
*
I35.0
ICD-10 Finland
Aortic (valve) stenosis
6.4
13.4
37
72
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
21.3
13.3
19
10
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
5.5
13.2
42
97
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
7.0
12.6
32
55
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
5.5
12.5
39
88
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
7.5
12.1
29
46
B01AB05
ATC
enoxaparin; parenteral
3.4
11.9
80
364
AP2
HP
Catheterization of the right side of the heart
+∞
11.6
11
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
7.7
11.6
27
41
J01CA04
ATC
amoxicillin; systemic
4.3
11.5
137
951
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
46.8
11.1
13
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
6.1
11.1
31
61
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
19.5
11.0
16
9
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.2
10.9
78
365
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.7
10.9
28
49
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.9
10.8
50
167
AP3
HP
Catheterization of the right and left side of the heart
64.3
10.8
12
*
I48.2
ICD-10 Finland
Chronic atrial fibrillation
11.8
10.6
19
18
413
HP
Radioablation / Microwave Maze also as an adjunct to other procedures
+∞
10.5
10
*
C07AB02
ATC
metoprolol; systemic
3.4
10.5
62
251
AQ1
HP
Conventional electrophysiological examination
16.0
10.2
16
11
C07AA07
ATC
sotalol; systemic
6.7
9.9
25
43
AF1
HP
Surgery of congenital heart defect
+∞
9.5
9
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
5.9
8.9
25
49
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
4.8
8.7
29
70
C08DA01
ATC
verapamil; systemic
6.5
8.7
22
38
AB2
HP
AVR bio, stent
29.3
8.6
11
*
Z50.0
ICD-10 Finland
Cardiac rehabilitation
13.8
8.5
14
11
FL1AC
NOMESCO Finland
Left cardioangiography
13.8
8.5
14
11
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
94.7
8.5
9
*
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
8.3
8.4
18
24
J01MA12
ATC
levofloxacin; systemic
3.3
8.4
48
183
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
8.4
8
*
AD1
HP
TVP
+∞
8.4
8
*
FKD00
NOMESCO Finland
Replacement of mitral valve using mechanical prosthesis
+∞
8.4
8
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.1
8.3
52
214
WX870
NOMESCO Finland
Other postsurgical intensive care
35.3
8.2
10
*
I47.1
ICD-10 Finland
Supraventricular tachycardia
7.3
8.2
19
29
342
Kela drug reimbursment
Dronedarone
23.4
8.1
11
5
N02BE01
ATC
paracetamol; systemic, rectal
4.6
7.9
147
1176
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
16.1
7.8
12
8
FKC20
NOMESCO Finland
Plastic repair of mitral valve leaflet for insufficiency
47.3
7.8
9
*
I50.0
ICD-10 Finland
Congestive heart failure
4.4
7.8
28
73
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.9
7.8
25
58
TFP34
NOMESCO Finland
Electrophysiological investigation
7.5
7.5
17
25
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
7.5
51
220
TFP35
NOMESCO Finland
Electroanatomical mapping
14.3
7.5
12
9
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
83.7
7.5
8
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.9
7.4
24
56
C03DA01
ATC
spironolactone; oral
3.5
7.4
35
117
R4110
NOMESCO Finland
Physiotherapy
2.7
7.3
62
303
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
31.5
7.2
9
*
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
21.2
7.2
10
5
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
12.8
7.2
12
10
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
4.2
7.1
27
74
I49.5
ICD-10 Finland
Sick sinus syndrome
5.6
7.1
20
40
K83
ICPC
Heart valve disease NOS
14.6
7.0
11
8
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
10.0
6.9
13
14
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
13.0
6.7
11
9
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
3.7
6.7
29
90
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.5
6.6
23
58
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.9
6.5
26
75
Q21.19
ICD-10 Finland
Atrial septal defect NOS
72.5
6.5
7
*
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
72.5
6.5
7
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
72.5
6.5
7
*
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
9.9
6.4
12
13
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
6.3
39
157
XF620
NOMESCO Finland
Examination of circulation with color method
+∞
6.3
6
*
AC2
HP
MVR bio
+∞
6.3
6
*
FKC00
NOMESCO Finland
Repair of mitral valve for insufficiency using ring
+∞
6.3
6
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.3
6.3
32
113
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
8.2
6.3
13
17
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.6
6.2
51
242
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
13.2
6.2
10
8

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: AF_OPER_OTHER – Other operation for atrial fibrillation

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).