This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Operations for atrial fibrillation
AF_OPER
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
499 |
6. Filter based on genotype QC (FinnGen only) |
499 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF4
Similar endpoints
↥List of similar endpoints to
Operations for atrial fibrillation
based on the number of shared cases.
Similar with more cases:
- Other heart diseases
- Other heart diseases, wide
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
- Any operation in hilmo
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 499 | 132 | 367 |
| Unadjusted period prevalence (%) | 0.13 | 0.04 | 0.16 |
| Median age at first event (years) | 64.76 | 66.68 | 64.07 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 456
- Matched controls
- 4561
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
75.5
253.7
287
100
I48
ICD-10 Finland
Atrial fibrillation and flutter
82.2
247.7
433
849
B01AA03
ATC
warfarin; systemic
56.6
244.6
417
724
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
45.0
233.7
308
201
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
+∞
185.4
165
*
I34.1
ICD-10 Finland
Mitral (valve) prolapse
60.0
183.4
214
66
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
+∞
176.9
158
*
TFP20
NOMESCO Finland
Cardiodefibrillation
25.8
174.0
269
240
WX872
NOMESCO Finland
Intensive care
33.6
173.5
238
143
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
267.3
162.8
158
9
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
+∞
155.3
140
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
16.2
149.3
361
865
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
15.7
148.9
322
604
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
63.1
127.8
147
34
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
12.4
122.8
280
517
C07AB07
ATC
bisoprolol; oral
22.6
122.1
427
1798
207
Kela drug reimbursment
Chronic arrhythmias
11.8
117.5
273
511
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
61.3
114.1
132
30
FFM10
NOMESCO Finland
Occlusion or excision of atrial appendage externally with a closing device
1290.3
108.0
101
*
C01BD01
ATC
amiodarone; systemic
25.5
103.1
149
85
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
+∞
96.3
89
*
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
186.1
88.7
90
6
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
27.8
79.9
111
52
AC4
HP
MVP
140.2
77.8
81
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.6
77.7
372
1671
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
16.9
72.2
120
94
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
24.3
71.2
103
54
C01AA05
ATC
digoxin; systemic
10.6
69.2
147
195
FKC60
NOMESCO Finland
Resection and reconstruction of leaflet of mitral valve for insufficiency
388.6
67.4
66
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
6.7
67.0
213
526
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
94.8
66.2
72
9
XF404
NOMESCO Finland
Ambulatory ECG
8.3
66.0
168
300
C03CA01
ATC
furosemide; systemic
5.7
65.6
278
974
WX408
NOMESCO Finland
General anesthesy, balanced
5.5
61.7
262
899
R4110
NOMESCO Finland
Physiotherapy
5.4
59.7
257
885
FFM30
NOMESCO Finland
Occlusion of atrial appendage internally by internal suture ligation
+∞
56.4
53
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
9.5
55.3
123
170
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
6.0
54.9
183
456
AH2
HP
Treatment of atrial fibrillation by maze surgery or its modification as the only procedure
+∞
51.0
48
*
K78
ICPC
Atrial fibrillation/flutter
7.1
50.5
139
265
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
10.1
49.9
106
133
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.5
49.2
117
178
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.6
47.0
218
755
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
133.7
45.7
48
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.2
44.9
137
294
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
24.5
43.6
62
29
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.7
42.3
176
534
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
30.2
41.9
56
21
AN1
HP
Coronary angiography
4.9
41.8
164
467
XF400
NOMESCO Finland
ECG with 12 standard connections
4.7
41.2
171
515
I50.9
ICD-10 Finland
Heart failure, unspecified
5.1
41.1
153
410
C01BC04
ATC
flecainide; systemic
10.7
40.3
81
90
C07AA07
ATC
sotalol; systemic
9.1
34.6
76
98
K83
ICPC
Heart valve disease NOS
24.8
33.4
47
21
B01AB05
ATC
enoxaparin; parenteral
3.4
31.9
225
1021
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.1
31.8
151
496
WZC30
NOMESCO Finland
Teaching
4.3
31.0
134
402
I35.0
ICD-10 Finland
Aortic (valve) stenosis
6.2
30.5
88
169
FKD10
NOMESCO Finland
Replacement of mitral valve using biological prosthesis
40.1
29.8
37
10
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
31.7
29.0
38
13
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
28.9
174
688
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
6.6
28.1
76
133
AA1
HP
Conventional CABG
10.3
27.3
55
60
AP3
HP
Catheterization of the right and left side of the heart
42.9
26.2
32
8
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
5.0
26.0
91
217
C03DA01
ATC
spironolactone; oral
4.2
25.7
109
316
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
17.6
25.0
39
24
PD5BD
NOMESCO Finland
Extensive CT of aorta
10.6
24.9
49
51
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
5.6
24.9
77
159
B01AF02
ATC
apixaban; oral
4.2
24.7
106
309
FKC20
NOMESCO Finland
Plastic repair of mitral valve leaflet for insufficiency
57.2
23.3
27
5
XF402
NOMESCO Finland
ECG with work load test
3.9
22.9
107
335
201
Kela drug reimbursment
Chronic cardiac insufficiency
6.4
22.2
61
108
AP1
HP
Catheterization of the left side of the heart
12.4
22.2
40
35
WX892
NOMESCO Finland
Monitored bed care
4.4
22.1
87
232
K84
ICPC
Heart disease other
8.4
22.0
49
64
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
5.3
21.7
70
151
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
33.0
21.7
28
9
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
16.8
20.9
33
21
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
5.1
20.7
68
150
I50.0
ICD-10 Finland
Congestive heart failure
4.5
20.6
78
200
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
5.4
20.0
63
132
C09AA05
ATC
ramipril; oral
2.7
19.9
185
924
AD1
HP
TVP
109.8
19.7
21
*
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
109.8
19.7
21
*
I47.1
ICD-10 Finland
Supraventricular tachycardia
6.6
19.4
51
85
FKC96
NOMESCO Finland
Other repair of mitral valve for insufficiency
48.2
19.4
23
5
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
21.2
19.3
28
14
WX402
NOMESCO Finland
General anaesthesia
3.1
18.6
120
471
N02BE01
ATC
paracetamol; systemic, rectal
3.9
18.6
420
3422
TFP35
NOMESCO Finland
Electroanatomical mapping
12.2
18.3
33
29
TFP34
NOMESCO Finland
Electrophysiological investigation
6.9
18.2
46
73
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
10.4
18.0
35
36
AB2
HP
AVR bio, stent
21.1
17.9
26
13
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
5.2
17.9
57
121
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
6.3
17.8
48
83
342
Kela drug reimbursment
Dronedarone
17.8
17.6
27
16
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
30.2
17.6
23
8
B01AF01
ATC
rivaroxaban; oral
3.3
17.5
100
361
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
32.9
17.2
22
7
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
7.6
17.0
40
57
AP2
HP
Catheterization of the right side of the heart
36.6
16.8
21
6
K80
ICPC
Cardiac arrhythmia NOS
4.1
16.6
68
187
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.5
16.5
166
848
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
4.3
16.5
64
167
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
9.7
15.9
32
35
C01BD07
ATC
dronedarone; oral
18.0
15.8
24
14
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
3.3
15.6
85
294
J01CA04
ATC
amoxicillin; systemic
2.6
15.3
372
2887
I49.5
ICD-10 Finland
Sick sinus syndrome
5.1
15.1
49
106
FKC00
NOMESCO Finland
Repair of mitral valve for insufficiency using ring
58.7
14.9
17
*
XF620
NOMESCO Finland
Examination of circulation with color method
21.9
14.8
21
10
FL1AC
NOMESCO Finland
Left cardioangiography
9.9
14.7
29
31
B01AE07
ATC
dabigatran etexilate; oral
4.8
14.5
49
111
FKD00
NOMESCO Finland
Replacement of mitral valve using mechanical prosthesis
44.0
14.2
17
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
14.1
82
295
I48.1
ICD-10 Finland
Persistent atrial fibrillation
6.6
14.1
36
58
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
6.2
14.1
38
66
XF640
NOMESCO Finland
NA
6.3
13.9
37
63
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.1
13.8
55
147
I48.2
ICD-10 Finland
Chronic atrial fibrillation
6.4
13.8
36
60
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
6.2
13.8
37
64
AF1
HP
Surgery of congenital heart defect
+∞
13.6
13
*
I97.0
ICD-10 Finland
Postcardiotomy syndrome
35.2
13.6
17
5
AC2
HP
MVR bio
35.2
13.6
17
5
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
23.3
13.0
18
8
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
6.1
12.7
34
59
413
HP
Radioablation / Microwave Maze also as an adjunct to other procedures
+∞
12.6
12
*
FKC10
NOMESCO Finland
Suture of cleft mitral leaflet
+∞
12.6
12
*
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
11.5
12.2
22
20
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
12.2
11.9
21
18
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
13.0
11.7
20
16
WX870
NOMESCO Finland
Other postsurgical intensive care
19.5
11.7
17
9
C01BA03
ATC
disopyramide; systemic
19.5
11.7
17
9
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
10.4
11.6
22
22
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.6
11.6
53
160
I34
ICD-10 Finland
Nonrheumatic mitral valve disorders
+∞
11.5
11
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
122.9
11.5
12
*
AR6
HP
Catheter ablation of arrhythmia, target: atrial fibrillation
20.7
11.2
16
8
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.6
11.2
51
154
I49.3
ICD-10 Finland
Ventricular premature depolarization
3.5
10.9
51
157
C08DA01
ATC
verapamil; systemic
4.3
10.7
39
96
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
61.4
10.7
12
*
AJX
HP
Other surgery on the heart or aorta
112.5
10.5
11
*
I47.2
ICD-10 Finland
Ventricular tachycardia
5.5
10.3
30
58
Q21.10
ICD-10 Finland
Persistent ostium secundum
24.0
10.3
14
6
3A064
NOMESCO Finland
NA
24.0
10.3
14
6
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
24.0
10.3
14
6
AQ1
HP
Conventional electrophysiological examination
8.2
10.2
22
28
N02AX02
ATC
tramadol; systemic, rectal
1.9
10.1
227
1557
M01AE01
ATC
ibuprofen; systemic, rectal
0.5
10.1
285
3501
A02BC02
ATC
pantoprazole; systemic
1.9
10.1
315
2434
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.7
10.0
72
297
C07AB02
ATC
metoprolol; systemic
2.1
9.9
127
699
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
8.7
9.7
20
24
WW502
NOMESCO Finland
Autotransfusion
11.7
9.6
17
15
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
9.6
197
1303
I44.2
ICD-10 Finland
Atrioventricular block, complete
4.9
9.5
30
64
71
HP
Electrophysiological Special Examination
18.0
9.5
14
8
742
NOMESCO Finland
NA
30.7
9.4
12
*
FM1CD
NOMESCO Finland
Very extensive CT of heart
22.2
9.4
13
6
H03BB01
ATC
carbimazole; oral
4.9
9.4
30
65
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
6.5
9.2
23
37
Q23.11
ICD-10 Finland
Bicuspid aortic valve
11.8
9.1
16
14
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
19.1
9.0
13
7
K99
ICPC
Cardiovascular disease other
4.4
8.9
31
74
C07AB03
ATC
atenolol; systemic
3.3
8.8
43
138
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
3.3
8.7
44
144
WX002
NOMESCO Finland
Sedation and analgesia
2.1
8.6
111
606
FCA70
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of biological valve prosthesis and tube graft
16.7
8.6
13
8
GAA31
NOMESCO Finland
Thoracoscopy
28.1
8.5
11
*
I34.8
ICD-10 Finland
Other nonrheumatic mitral valve disorders
20.5
8.5
12
6
I50.1
ICD-10 Finland
Left ventricular failure
3.5
8.4
39
120
GD1LA
NOMESCO Finland
GD
6.0
8.4
22
38
TFP32
NOMESCO Finland
Cathetric treatmen of cardiac arrythmia
11.0
8.3
15
14
WX902
NOMESCO Finland
External defibrillation of heart
11.0
8.3
15
14
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
10.3
8.1
15
15
FPW96
NOMESCO Finland
Other operation for arhythmia or disturbance of impulse propagation
13.3
7.9
13
10
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
5.0
7.9
24
50
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
5.7
7.8
21
38
B01AF03
ATC
edoxaban; oral
7.6
7.7
17
23
R06.0
ICD-10 Finland
Dyspnoea
1.9
7.4
129
787
FFM20
NOMESCO Finland
Amputation of atrial appendage
+∞
7.3
7
*
3A422
NOMESCO Finland
NA
+∞
7.3
7
*
474
NOMESCO Finland
NA
+∞
7.3
7
*
Q21.30
ICD-10 Finland
Tetralogy of Fallot
+∞
7.3
7
*
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
4.8
7.3
23
50
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
30.5
7.2
9
*
I48.4
ICD-10 Finland
Atypical atrial flutter
20.4
7.2
10
5
81
HP
Angiography of the heart and coronary arteries
2.7
7.1
48
189
XF600
NOMESCO Finland
Bloodpressure measurement
2.8
7.0
42
157
WZA00
NOMESCO Finland
Short statement of of health and health related matters
3.1
6.9
36
122
R04.0
ICD-10 Finland
Epistaxis
2.6
6.9
48
195
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.9
6.9
27
73
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
11.2
6.8
12
11
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
11.2
6.8
12
11
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.8
6.8
21
45
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
40.7
6.8
8
*
72
HP
Catheter ablation of arrhythmia
17.0
6.8
10
6
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.7
6.7
43
167
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
6.0
6.7
17
29
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
10.2
6.6
12
12
ZX120
NOMESCO Finland
Intravenous
2.4
6.5
57
261
A12BA01
ATC
potassium chloride; oral
3.3
6.4
30
94
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
6.4
124
780
FFM00
NOMESCO Finland
Occlusion or excision of atrial appendage by ligation
+∞
6.3
6
*
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
+∞
6.3
6
*
3A149
NOMESCO Finland
NA
+∞
6.3
6
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
6.3
6
*
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
+∞
6.3
6
*
FKC40
NOMESCO Finland
Suture of chord or papillary muscle of mitral valve
+∞
6.3
6
*
FGD00
NOMESCO Finland
Repair of tricuspid valve using suture
+∞
6.3
6
*
120
NOMESCO Finland
NA
+∞
6.3
6
*
FPB22
NOMESCO Finland
Transvenous radiofrequency ablation of aberrant pathway or focus of heart
27.1
6.2
8
*
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
4.5
6.1
20
46
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
12.7
6.1
10
8
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
261
462
10.75
160.31
2.8
2.5
27.3
7.6
ug/l
15.08
256
408
303
656
10.21
155.44
46.5
25.4
2.2
1.3
inr
5.15
15
89
295
768
7.95
121.48
2.8
2.2
32.7
29.7
s
12.12
290
744
194
394
7.42
99.58
3.1
2.8
288.4
205.5
ng/l
1.79
183
356
376
1487
7.20
92.13
4.7
3.1
1603.6
1437.1
ng/l
0.31
367
1292
302
1094
5.46
78.31
2.5
2.6
—
—
—
0
0
266
880
5.33
76.78
5.3
3.9
3074.3
389.9
ng/l
6.71
254
741
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
114
186
7.65
70.23
3.9
2.5
0.3
0.4
u/ml
1.38
76
93
211
769
4.02
49.38
4.4
3.8
0.8
0.8
mmol/l
3.39
197
724
175
570
4.19
47.79
3.1
4.4
273.0
247.6
u/l
0.94
167
539
298
1397
3.81
47.39
2.6
2.3
444.6
287.6
u/l
1.38
289
1317
372
2022
4.30
47.34
4.1
4.2
—
—
—
0
0
187
659
3.94
45.35
8.9
7.6
105.9
104.3
mmol/l
4.80
187
642
145
444
4.19
42.58
6.7
8.2
9.2
10.2
mmol/l
0.75
140
425
75
131
6.56
42.46
3.1
2.1
80.6
85.7
%
1.02
75
125
424
2686
4.85
39.85
8.8
5.4
6.6
6.8
mmol/l
1.76
408
2543
283
1390
3.39
39.64
3.0
3.7
35.2
35.0
u/l
0.03
277
1326
90
225
4.66
33.97
4.5
4.3
24.4
24.2
mmol/l
0.25
85
205
57
98
6.44
32.55
2.9
3.0
0.7
0.9
nmol/l
0.80
48
79
380
2389
3.48
32.44
6.5
7.1
17.4
12.3
umol/l
5.25
367
2276
152
594
3.24
29.70
12.9
8.2
5.1
5.1
kpa
0.10
144
574
152
594
3.24
29.70
12.9
8.2
13.7
11.9
kpa
1.82
145
576
150
596
3.17
28.35
13.0
8.2
0.9
1.1
mmol/l
0.21
124
468
91
288
3.64
24.51
17.8
11.0
—
—
—
0
0
81
242
3.80
23.71
2.2
1.7
1.2
1.6
g/l
1.77
66
209
157
701
2.81
23.48
2.9
2.6
2.3
2.3
g/l
1.00
148
653
165
757
2.76
23.40
2.9
2.6
12.2
12.8
umol/l
0.39
157
705
93
312
3.43
22.82
5.1
3.4
123.8
128.3
g/l
0.98
86
307
150
669
2.78
22.33
3.0
2.6
20.7
22.8
%
0.99
129
576
116
450
3.06
22.33
4.2
4.0
1.7
2.0
mmol/l
0.44
100
355
116
451
3.05
22.23
4.3
4.0
5.8
5.8
kpa
0.09
110
440
20
14
14.84
22.03
11.2
7.8
—
—
—
0
0
318
2051
2.52
21.44
10.1
6.7
1.2
1.2
mmol/l
7.93
300
1869
98
375
3.01
19.12
3.8
3.1
4.5
4.5
kpa
0.06
93
364
435
3376
3.25
18.54
8.8
8.4
78.5
80.2
u/l
0.35
421
3175
201
1109
2.36
18.52
2.7
2.1
2.9
3.1
mg/l
0.88
176
944
327
2226
2.36
18.20
10.6
7.7
1.2
1.2
mmol/l
10.55
293
1905
37
79
4.98
16.62
1.4
1.5
—
—
—
0
0
37
79
4.98
16.62
1.4
1.5
—
—
—
0
0
70
239
3.24
16.48
3.4
2.7
1.2
1.2
%
0.01
70
239
129
633
2.40
15.06
6.1
6.5
1.0
1.0
mmol/l
1.35
120
585
271
1807
2.09
14.55
6.0
4.0
79.0
42.9
ng/l
1.06
217
1394
248
1633
2.03
13.42
3.4
2.7
157.2
177.3
ug/l
0.61
228
1492
110
539
2.34
12.68
2.2
3.2
12.3
9.6
umol/l
0.41
98
483
159
921
2.07
11.98
2.4
1.7
1.9
1.3
mg/l
1.06
123
724
80
351
2.52
11.71
3.5
3.1
65.9
63.2
ml/min/173m2
0.19
35
145
108
548
2.24
11.37
1.9
1.9
—
—
—
0
0
474
4149
3.84
11.15
28.0
16.6
37.0
26.8
mg/l
8.02
443
3378
438
3680
2.56
11.13
5.7
4.3
2.1
2.0
mu/l
0.91
398
3307
106
546
2.20
10.71
1.8
1.9
—
—
—
0
0
142
828
2.00
10.28
3.0
2.9
0.6
1.0
e6/l
1.42
78
506
271
1955
1.85
10.14
4.9
5.4
34.7
35.0
g/l
0.43
254
1830
135
778
2.01
10.08
3.2
3.2
1.6
1.3
e6/l
0.16
71
462
199
1311
1.86
9.92
3.7
3.3
0.4
0.5
e6/l
0.23
146
1005
323
2473
1.87
9.86
8.4
9.7
4.3
4.2
e9/l
0.51
267
2176
133
779
1.96
9.40
1.9
2.0
—
—
—
0
0
42
153
2.91
8.78
5.4
3.6
4.2
4.0
mmol/l
1.61
42
140
14
22
6.52
8.57
2.1
2.3
79.6
106.9
%
2.26
14
22
359
2917
1.82
8.20
4.5
3.5
15.5
15.0
pmol/l
3.06
327
2600
67
322
2.25
7.91
1.5
1.7
—
—
—
0
0
202
1439
1.68
7.09
3.8
3.4
108.8
111.9
e6/l
0.01
146
1132
421
3673
1.94
6.73
38.2
17.6
38.1
40.1
%
5.22
328
2475
370
3109
1.74
6.67
4.1
4.1
14.6
13.0
mm/h
1.00
342
2861
31
112
2.88
6.60
1.1
1.3
—
—
—
0
0
44
193
2.40
6.40
5.1
3.7
1.1
1.5
mmol/l
2.85
44
187
478
4428
2.89
5.80
14.8
11.7
26.7
27.8
u/l
0.88
469
4275
445
4006
2.02
5.76
4.9
4.3
1.2
1.3
mmol/l
2.05
416
3644
224
1704
1.57
5.68
3.9
3.4
—
—
—
0
0
175
1260
1.60
5.60
3.0
3.0
2261.5
7123.5
umol/l
1.33
152
1080
73
417
1.88
5.38
3.0
2.5
38.0
34.4
u/l
0.35
65
357
53
271
2.07
5.36
1.5
1.5
—
—
—
0
0
39
177
2.31
5.28
1.3
3.2
3.5
3.2
g/l
0.72
30
143
461
4235
2.16
5.14
6.1
5.4
2.5
2.6
mmol/l
2.07
439
3869
441
3991
1.90
5.12
29.3
15.4
75.7
77.7
ml/min/173m2
1.33
409
3352
454
4156
2.02
4.98
5.4
4.8
4.2
4.5
mmol/l
4.14
432
3818
40
189
2.21
4.94
1.3
3.0
4.1
3.7
g/l
1.04
31
141
40
189
2.21
4.94
1.3
3.0
—
—
—
0
0
40
189
2.21
4.94
1.3
3.0
7.1
7.4
g/l
0.20
31
147
13
32
4.14
4.92
1.5
1.5
—
—
—
0
0
13
32
4.14
4.92
1.5
1.5
—
—
—
0
0
452
4137
1.98
4.87
5.1
5.0
6.0
6.1
mmol/l
1.20
424
3753
451
4131
1.95
4.75
5.3
4.8
1.3
1.4
mmol/l
2.46
429
3767
234
1854
1.49
4.62
2.1
2.0
96.6
93.2
pmol/l
0.59
114
996
482
4558
2.69
4.19
43.6
24.2
214.5
238.3
e9/l
16.38
475
4442
482
4560
2.67
4.15
43.7
24.2
4.3
4.5
e12/l
16.12
474
4430
151
1126
1.49
3.88
1.6
1.6
18.1
20.2
nmol/l
1.19
131
940
65
402
1.71
3.68
1.7
3.3
65.9
66.3
g/l
0.14
60
364
53
311
1.79
3.60
1.6
1.7
—
—
—
0
0
24
105
2.35
3.58
1.5
1.6
—
—
—
0
0
30
146
2.12
3.49
1.9
1.7
—
—
—
0
0
28
136
2.12
3.29
1.8
1.6
—
—
—
0
0
27
130
2.14
3.24
1.5
1.5
—
—
—
0
0
23
111
2.12
2.77
1.1
1.2
—
—
—
0
0
114
862
1.42
2.63
1.8
1.7
999.4
1183.5
nmol/l
1.50
82
659
9
25
3.65
2.58
1.2
1.4
—
—
—
0
0
110
829
1.42
2.58
3.0
3.4
2.5
2.5
mmol/l
0.13
89
733
29
158
1.89
2.54
1.4
1.7
—
163.3
—
0
6
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
12
5.05
2.41
1.7
2.4
172.8
150.1
%
—
6
12
22
111
2.03
2.39
1.1
1.2
—
—
—
0
0
79
568
1.46
2.38
11.9
7.8
—
—
—
0
0
7
18
3.93
2.26
1.0
1.1
—
—
—
0
0
188
1572
1.31
2.25
2.0
2.3
79.4
76.7
nmol/l
0.61
155
1374
172
1422
1.32
2.23
3.3
3.7
2.3
2.3
mmol/l
0.06
138
1241
426
4003
1.44
2.18
6.0
6.4
39.5
40.8
mmol/mol
3.06
399
3698
20
101
2.02
2.18
6.1
6.8
705.2
257.1
iu/ml
—
5
19
25
137
1.87
2.17
1.0
1.4
—
—
—
0
0
7
19
3.72
2.15
3.0
4.9
—
—
—
0
0
21
112
1.91
1.99
2.2
1.6
—
—
—
0
0
247
2167
1.28
1.98
2.2
2.4
—
—
—
0
0
22
121
1.86
1.91
1.5
1.9
—
—
—
0
0
34
213
1.64
1.91
2.6
2.0
0.5
2.8
ug/l
1.02
25
189
12
53
2.30
1.82
1.6
1.2
2.0
9.0
u/ml
—
5
10
26
155
1.71
1.76
1.1
1.3
—
—
—
0
0
15
75
2.03
1.71
1.8
2.8
—
788.7
—
0
9
21
120
1.78
1.65
1.5
1.9
—
—
—
0
0
14
70
2.03
1.60
1.6
1.9
—
—
—
0
0
22
131
1.71
1.52
1.2
1.3
—
—
—
0
0
21
125
1.71
1.46
1.1
1.7
4604.9
15600.5
e6/l
1.66
14
97
135
1578
0.80
1.39
3.9
3.9
—
—
—
0
0
76
951
0.76
1.37
1.6
1.8
475.2
19872216.8
pmol/l
0.69
66
780
9
42
2.16
1.34
1.0
1.0
—
—
—
0
0
8
34
2.37
1.29
1.1
1.4
—
—
—
0
0
17
102
1.69
1.17
1.5
1.3
—
—
—
0
0
8
39
2.07
1.15
1.0
1.2
—
—
—
0
0
8
41
1.97
1.09
1.0
1.0
320.1
292.7
mg/l
—
8
36
15
89
1.71
1.08
1.5
2.0
—
—
—
0
0
44
333
1.35
1.06
4.0
4.0
139.7
92.8
ng/l
1.48
37
290
9
46
1.97
1.04
1.2
1.4
—
—
—
0
0
10
53
1.90
1.02
1.6
2.0
—
—
—
0
0
12
68
1.78
1.01
1.3
1.4
—
—
—
0
0
18
272
0.65
1.01
3.2
3.0
0.1
0.2
e6/l
1.69
18
265
9
49
1.85
0.99
1.0
1.1
—
—
—
0
0
5
23
2.19
0.98
1.0
2.4
2255.6
948.1
u/ml
—
5
23
17
108
1.59
0.97
1.5
2.5
127.1
126.9
g/l
—
8
79
25
175
1.45
0.95
1.2
1.2
16.7
131.8
iu/ml
—
5
59
161
1438
1.18
0.93
2.6
2.6
65.4
57.9
u/l
0.81
151
1345
9
52
1.74
0.93
3.0
2.9
—
—
—
0
0
6
28
2.16
0.91
2.5
1.5
—
—
—
0
0
291
2735
1.15
0.84
3.4
3.4
71.6
58.0
u/l
1.30
271
2549
25
180
1.41
0.83
1.2
1.5
—
—
—
0
0
21
294
0.70
0.82
2.1
1.8
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
38
479
0.78
0.76
1.9
2.3
11.6
13.1
nmol/l
0.79
33
423
218
2018
1.14
0.76
3.4
3.7
0.0
0.0
estimate
0.00
25
388
13
83
1.58
0.75
1.1
1.1
—
—
—
0
0
7
38
1.85
0.74
1.7
1.9
—
—
—
0
0
25
185
1.37
0.73
1.6
3.0
—
—
—
0
0
48
584
0.80
0.73
4.9
4.8
34.6
31.5
%
1.39
38
395
29
221
1.33
0.71
17.0
5.4
1.9
1.6
%
0.88
24
211
10
63
1.60
0.62
1.3
1.6
—
—
—
0
0
8
50
1.61
0.61
1.1
1.2
83.8
112.0
%
—
8
45
0
20
0.00
0.60
0.0
3.3
—
—
—
0
0
0
20
0.00
0.60
0.0
3.3
—
—
—
0
0
56
476
1.20
0.59
4.4
3.6
—
—
—
0
0
218
2048
1.11
0.56
3.5
3.7
0.0
0.0
estimate
0.00
26
377
8
55
1.46
0.56
2.0
3.6
—
—
—
0
0
8
55
1.46
0.56
1.1
1.1
—
—
—
0
0
10
65
1.55
0.56
1.4
1.6
—
—
—
0
0
10
65
1.55
0.56
1.4
1.6
—
—
—
0
0
10
65
1.55
0.56
1.4
1.6
—
—
—
0
0
6
38
1.59
0.54
1.0
1.1
—
—
—
0
0
6
39
1.54
0.53
1.2
1.9
—
—
—
0
0
10
66
1.53
0.53
1.4
1.6
—
—
—
0
0
214
2016
1.11
0.52
4.9
5.0
0.0
0.0
estimate
0.00
27
394
101
1115
0.88
0.51
3.7
3.9
0.0
0.0
estimate
0.50
25
370
9
65
1.39
0.51
1.4
1.6
—
—
—
0
0
21
163
1.30
0.49
1.2
1.4
—
—
—
0
0
7
46
1.53
0.48
1.3
1.9
—
—
—
0
0
22
173
1.28
0.47
1.5
1.8
—
—
—
0
0
20
253
0.78
0.45
1.3
1.4
—
—
—
0
0
7
50
1.41
0.45
1.3
1.8
—
—
—
0
0
7
50
1.41
0.45
1.3
1.8
—
—
—
0
0
7
50
1.41
0.45
1.3
1.8
—
—
—
0
0
160
1498
1.10
0.43
2.7
3.1
0.7
0.8
ug/l
0.36
98
1015
5
31
1.62
0.43
1.0
1.2
—
—
—
0
0
8
59
1.36
0.41
1.8
2.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
23
188
1.23
0.38
1.7
2.0
—
—
—
0
0
155
1460
1.09
0.37
2.8
3.2
7.2
8.1
mmol/l
1.73
132
1207
216
2064
1.08
0.36
4.1
4.4
24.7
21.0
%
1.65
94
1004
12
90
1.34
0.36
1.2
1.7
—
—
—
0
0
9
123
0.73
0.35
1.8
2.2
—
—
—
0
0
16
129
1.25
0.30
1.4
1.5
0.0
0.0
iu/ml
—
5
27
7
56
1.25
0.29
1.9
2.0
—
—
—
0
0
5
72
0.69
0.26
1.0
1.1
1.7
1.6
g/l
—
5
64
9
73
1.24
0.25
1.1
1.8
—
—
—
0
0
27
308
0.87
0.25
2.0
3.9
1.4
1.8
mmol/l
0.19
21
238
83
777
1.08
0.24
1.2
1.2
0.8
1.4
u/ml
1.38
12
215
40
441
0.90
0.23
1.4
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
8
104
0.77
0.21
1.0
1.2
498.5
528.1
mg/l
—
8
99
0
12
0.00
0.21
0.0
1.3
—
0.7
—
0
7
49
531
0.91
0.21
3.5
4.7
5.7
37.0
ug/l
1.31
37
453
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
12
99
1.22
0.19
1.3
1.1
26.3
37.9
u/l
0.41
12
86
9
81
1.11
0.15
1.1
1.7
—
—
—
0
0
156
1516
1.04
0.14
3.3
4.0
15.5
9.6
mg/mmol
0.63
102
1001
8
98
0.81
0.14
1.0
1.1
—
11.7
—
0
9
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
7
68
1.03
0.08
1.1
1.0
—
—
—
0
0
8
77
1.04
0.07
1.0
1.1
—
—
—
0
0
9
85
1.06
0.07
1.4
1.3
—
—
—
0
0
9
86
1.05
0.07
1.2
1.7
—
—
—
0
0
16
172
0.93
0.06
1.0
1.0
—
—
—
0
0
38
395
0.96
0.06
3.0
2.2
402.6
370.0
nmol/l
0.64
33
365
252
2542
0.98
0.05
4.5
5.1
1.9
2.8
ug/l
1.44
225
2289
121
1192
1.02
0.05
1.5
1.7
1.3
1.4
mmol/l
0.57
109
994
62
633
0.98
0.03
1.3
1.2
24.8
37.5
iu/ml
0.98
27
195
91
896
1.02
0.03
4.0
4.0
1.0
1.0
kg/l
0.34
11
130
59
602
0.98
0.03
1.2
1.3
15.0
10.0
u/ml
0.16
18
230
11
102
1.08
0.03
2.5
2.9
16.2
15.7
%
—
6
52
11
116
0.95
0.00
1.5
1.5
—
—
—
0
0
24
243
0.99
0.00
1.3
1.4
—
46.1
—
0
14
28
278
1.01
0.00
2.4
2.5
—
13.5
—
0
11
50
502
1.00
0.00
1.8
1.9
1.7
1.6
%
0.41
40
414
5
49
1.02
0.00
1.2
1.0
—
2.3
—
0
16
5
49
1.02
0.00
1.8
2.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
109.2
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.0
—
—
—
0
0
9
91
0.99
0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
73.7
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
0.00
2.6
3.0
2.1
1.7
mg/l
0.64
13
117
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
12.8
—
0
5
7
71
0.99
0.00
1.1
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
27.2
—
0
5
7
74
0.95
0.00
1.1
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: AF_OPER – Operations for atrial fibrillation
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).