This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Maze procedure for atrial fibrillation
AF_MAZE
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
154 |
4. Check minimum number of eventsNone |
154 |
5. Include endpointsNone |
154 |
6. Filter based on genotype QC (FinnGen only) |
154 |
Control definitions (FinnGen only)
- Control exclude
- AF_OPER
Extra metadata
- First used in FinnGen datafreeze
- DF4
Similar endpoints
↥List of similar endpoints to
Maze procedure for atrial fibrillation
based on the number of shared cases.
Similar with more cases:
- Operations for atrial fibrillation
- Other heart diseases
- Other heart diseases, wide
- Cardiovascular diseases (excluding rheumatic etc)
- Antihypertensive medication - note that there are other indications
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 154 | 50 | 104 |
| Unadjusted period prevalence (%) | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | 64.51 | 67.24 | 63.20 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 140
- Matched controls
- 1400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
+∞
202.3
140
*
B01AA03
ATC
warfarin; systemic
114.3
84.5
134
228
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
72.5
82.2
94
38
I34.1
ICD-10 Finland
Mitral (valve) prolapse
138.1
81.5
82
14
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
51.7
77.9
99
62
I48
ICD-10 Finland
Atrial fibrillation and flutter
79.6
75.2
133
269
TFP20
NOMESCO Finland
Cardiodefibrillation
34.2
65.3
93
76
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
267.0
64.0
61
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
24.5
59.0
112
196
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
82.6
58.9
64
14
WX872
NOMESCO Finland
Intensive care
33.5
54.5
74
45
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
21.2
53.2
116
259
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
86.7
50.0
54
10
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
56.3
43.9
51
14
C07AB07
ATC
bisoprolol; oral
35.1
42.6
134
544
C01BD01
ATC
amiodarone; systemic
29.5
39.4
54
29
207
Kela drug reimbursment
Chronic arrhythmias
12.7
39.1
87
160
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
258.1
38.9
38
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
26.6
38.8
55
33
AC4
HP
MVP
486.3
37.9
36
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
11.5
36.8
87
174
R4110
NOMESCO Finland
Physiotherapy
10.4
35.3
100
270
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
+∞
33.7
31
*
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
90.5
27.0
29
*
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
301.6
25.6
25
*
C03CA01
ATC
furosemide; systemic
7.0
25.4
93
308
GD1AA
NOMESCO Finland
Thorax X-ray examination
8.1
25.2
116
522
FFM30
NOMESCO Finland
Occlusion of atrial appendage internally by internal suture ligation
+∞
24.7
23
*
WX408
NOMESCO Finland
General anesthesy, balanced
6.8
24.6
87
271
C01AA05
ATC
digoxin; systemic
11.0
24.3
50
67
XF400
NOMESCO Finland
ECG with 12 standard connections
7.3
23.7
70
168
FKC60
NOMESCO Finland
Resection and reconstruction of leaflet of mitral valve for insufficiency
100.7
23.5
25
*
XF404
NOMESCO Finland
Ambulatory ECG
8.3
22.0
55
101
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
6.6
21.0
66
167
WX404
NOMESCO Finland
Intravenous generell anesthesy
6.5
21.0
67
173
K78
ICPC
Atrial fibrillation/flutter
9.2
20.7
47
73
I50.9
ICD-10 Finland
Heart failure, unspecified
6.9
20.3
59
133
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
47.7
20.2
24
6
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
23.0
19.6
28
15
AN1
HP
Coronary angiography
6.3
18.4
57
137
FKD10
NOMESCO Finland
Replacement of mitral valve using biological prosthesis
204.9
18.0
18
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.6
17.4
40
62
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.8
17.2
58
153
C07AA07
ATC
sotalol; systemic
12.4
16.5
30
30
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
5.5
16.2
56
150
AH2
HP
Treatment of atrial fibrillation by maze surgery or its modification as the only procedure
+∞
15.9
15
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
9.2
15.7
34
47
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
51.2
15.5
18
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.3
14.8
43
92
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
48.0
14.5
17
*
C03DA01
ATC
spironolactone; oral
5.8
14.0
44
103
TPH04
NOMESCO Finland
Cathetrisation of vein
4.6
13.9
58
186
PD5BD
NOMESCO Finland
Extensive CT of aorta
14.3
13.2
22
18
C01BC04
ATC
flecainide; systemic
10.6
12.9
25
28
AP3
HP
Catheterization of the right and left side of the heart
35.8
12.9
16
5
B01AB05
ATC
enoxaparin; parenteral
3.8
12.3
75
329
FFM10
NOMESCO Finland
Occlusion or excision of atrial appendage externally with a closing device
+∞
11.6
11
*
AD1
HP
TVP
130.3
11.6
12
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
6.8
11.6
30
54
I50.0
ICD-10 Finland
Congestive heart failure
6.0
11.5
33
68
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
65.1
10.8
12
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
5.5
10.3
32
72
B01AF02
ATC
apixaban; oral
4.8
9.9
35
91
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.5
9.9
56
223
WX892
NOMESCO Finland
Monitored bed care
5.5
9.9
30
66
FKC20
NOMESCO Finland
Plastic repair of mitral valve leaflet for insufficiency
107.0
9.5
10
*
AC2
HP
MVR bio
+∞
9.5
9
*
C09AA05
ATC
ramipril; oral
3.2
9.4
65
295
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
5.7
9.3
27
56
K83
ICPC
Heart valve disease NOS
20.3
9.1
13
7
WZC30
NOMESCO Finland
Teaching
3.7
8.9
43
149
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
5.9
8.9
25
50
201
Kela drug reimbursment
Chronic cardiac insufficiency
6.9
8.6
21
35
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
6.9
8.6
21
35
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
8.4
8
*
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
8.4
8
*
FKC96
NOMESCO Finland
Other repair of mitral valve for insufficiency
+∞
8.4
8
*
XF620
NOMESCO Finland
Examination of circulation with color method
35.6
8.2
10
*
XF402
NOMESCO Finland
ECG with work load test
3.7
8.2
38
127
WX402
NOMESCO Finland
General anaesthesia
3.6
8.1
40
141
I47.1
ICD-10 Finland
Supraventricular tachycardia
7.9
7.8
17
24
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
26.7
7.7
10
*
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
21.4
7.2
10
5
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
21.4
7.2
10
5
N02BE01
ATC
paracetamol; systemic, rectal
4.5
7.1
130
1037
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
8.3
7.1
15
20
AA1
HP
Conventional CABG
7.4
7.1
16
24
I50.1
ICD-10 Finland
Left ventricular failure
6.1
6.9
18
33
I49.5
ICD-10 Finland
Sick sinus syndrome
6.1
6.9
18
33
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
5.1
6.6
20
44
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
5.1
6.6
20
44
TFP32
NOMESCO Finland
Cathetric treatmen of cardiac arrythmia
73.0
6.5
7
*
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
5.4
6.3
18
37
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
28.1
6.3
8
*
C01BA03
ATC
disopyramide; systemic
28.1
6.3
8
*
FKC10
NOMESCO Finland
Suture of cleft mitral leaflet
+∞
6.3
6
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.5
6.1
21
53
K84
ICPC
Heart disease other
7.8
6.1
13
18
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
82
134
11.95
54.65
2.6
2.9
29.1
9.1
ug/l
3.70
82
116
71
101
12.19
52.46
2.7
3.6
317.7
273.3
ng/l
0.27
66
92
102
314
7.66
35.15
2.6
2.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
39
48
10.54
30.96
4.3
1.8
0.3
0.3
u/ml
0.59
23
26
30
33
11.05
25.61
2.3
2.0
204.6
198.2
%
0.11
30
33
72
225
5.13
22.34
3.9
3.5
0.8
0.8
mmol/l
0.72
67
213
19
20
10.70
16.45
1.6
1.5
—
—
—
0
0
19
20
10.70
16.45
1.6
1.5
—
—
—
0
0
113
618
4.11
14.41
3.5
4.3
—
—
—
0
0
134
828
5.76
14.40
9.2
4.6
6.5
6.9
mmol/l
1.38
129
784
43
130
4.20
13.10
3.4
4.3
1.7
1.8
mmol/l
0.06
37
99
50
176
3.73
12.21
15.1
6.9
-0.2
1.0
mmol/l
1.52
42
145
56
214
3.54
12.05
3.6
3.0
0.7
1.7
e6/l
0.86
24
116
59
238
3.40
11.60
3.3
2.7
0.8
1.1
e6/l
0.63
27
139
18
29
6.90
11.00
1.1
1.1
—
—
—
0
0
101
627
2.77
8.33
11.4
5.8
1.2
1.2
mmol/l
1.48
95
561
65
324
2.74
8.32
2.8
2.0
2.9
3.3
mg/l
0.72
57
283
73
400
2.57
7.56
4.6
3.0
0.4
0.4
e6/l
0.02
50
305
40
168
2.87
6.94
1.8
1.9
—
—
—
0
0
136
1037
3.66
6.90
9.2
7.9
77.2
79.8
u/l
0.34
131
971
39
165
2.83
6.66
1.8
1.8
—
—
—
0
0
23
74
3.48
6.19
1.6
1.8
—
—
—
0
0
80
493
2.30
6.01
3.1
2.6
142.3
167.4
ug/l
0.53
74
453
100
678
2.35
5.97
11.4
7.0
1.2
1.2
mmol/l
2.46
93
565
82
515
2.27
5.84
4.9
3.2
—
—
—
0
0
28
110
2.89
5.42
2.7
2.6
63.5
61.1
ml/min/173m2
—
8
50
23
82
3.12
5.25
3.4
2.8
1.5
1.3
%
0.19
23
82
106
760
2.27
5.22
8.4
9.8
4.3
4.3
e9/l
0.01
84
666
53
293
2.23
4.99
2.2
1.7
1.5
1.6
mg/l
0.10
44
236
43
228
2.23
4.42
2.0
1.9
—
—
—
0
0
27
526
0.41
4.39
3.2
4.1
—
—
—
0
0
79
539
1.96
4.05
2.3
2.0
95.5
92.5
pmol/l
0.28
42
279
143
1232
3.25
3.81
33.0
15.0
75.6
77.3
ml/min/173m2
0.44
133
1020
137
1160
2.64
3.68
6.8
4.4
2.0
2.0
mu/l
0.14
127
1025
116
922
2.05
3.61
5.2
3.6
15.5
15.0
pmol/l
1.01
106
806
7
9
8.08
3.59
1.3
1.0
—
—
—
0
0
7
9
8.08
3.59
1.0
1.8
14.0
12.4
u/l
—
7
9
7
9
8.08
3.59
1.3
1.0
—
—
—
0
0
13
42
3.29
3.46
1.6
1.4
—
—
—
0
0
12
38
3.34
3.29
1.8
1.3
—
—
—
0
0
132
1116
2.28
3.27
47.1
16.3
38.2
39.9
%
2.60
117
744
144
1270
3.06
3.18
31.1
15.9
36.1
25.5
mg/l
3.19
133
1042
19
81
2.54
3.13
1.9
1.3
—
—
—
0
0
43
259
1.92
3.05
3.6
3.0
2.5
2.5
mmol/l
0.33
33
232
6
10
6.19
2.72
1.3
1.3
6.3
6.5
u/l
—
6
10
6
11
5.62
2.57
1.3
1.2
—
—
—
0
0
13
51
2.69
2.51
1.3
1.7
35.4
37.7
g/l
0.89
13
45
11
40
2.88
2.43
1.1
1.3
—
—
—
0
0
11
41
2.81
2.33
2.1
1.4
—
—
—
0
0
7
177
0.37
2.21
4.1
4.9
36.6
31.6
%
—
7
111
60
434
1.63
2.18
3.3
3.3
2.4
2.3
mmol/l
0.33
50
379
18
90
2.13
2.10
1.8
1.6
—
—
—
0
0
13
59
2.31
1.90
1.3
1.7
13.2
10.2
g/l
0.76
13
52
10
40
2.60
1.87
1.1
1.3
—
—
—
0
0
12
53
2.37
1.86
1.1
1.3
—
—
—
0
0
5
12
4.27
1.83
2.6
1.3
155.3
129.3
u/l
—
5
12
139
1266
2.01
1.81
4.5
5.0
6.0
6.1
mmol/l
0.44
130
1137
12
54
2.33
1.79
4.8
3.5
4.1
4.0
mmol/l
0.27
12
49
146
1366
2.32
1.71
41.5
19.0
90.1
82.9
umol/l
1.43
146
1366
13
63
2.16
1.65
1.3
1.7
—
—
—
0
0
13
63
2.16
1.65
1.3
1.7
7.1
7.6
g/l
0.22
13
50
13
63
2.16
1.65
1.3
1.7
4.2
3.7
g/l
0.52
13
48
11
50
2.29
1.61
1.2
3.3
40.6
31.2
mg/l
0.40
11
40
11
50
2.29
1.61
1.2
3.3
—
3.0
—
0
8
11
50
2.29
1.61
1.2
3.3
221.1
50.6
mg/l
0.49
11
40
136
1244
1.80
1.54
4.2
4.3
1.1
1.3
mmol/l
2.82
129
1120
7
27
2.67
1.53
1.7
1.6
—
—
—
0
0
6
21
2.93
1.52
1.2
1.3
—
—
—
0
0
138
1272
1.82
1.46
4.6
4.8
1.3
1.4
mmol/l
1.32
131
1149
72
587
1.43
1.35
5.2
4.1
23.0
44.9
ng/l
1.69
56
443
44
331
1.46
1.26
1.9
1.6
14.9
20.1
nmol/l
2.05
37
278
110
978
1.44
1.21
4.1
4.2
14.4
12.6
mm/h
0.55
105
892
7
140
0.48
1.16
1.7
1.3
—
—
—
0
0
140
1313
1.73
1.14
5.6
5.4
2.5
2.7
mmol/l
0.92
134
1189
5
21
2.43
1.10
1.6
1.4
—
97.4
—
0
7
7
35
2.05
1.01
2.1
1.5
—
—
—
0
0
51
410
1.36
0.99
2.8
3.1
0.7
0.8
ug/l
0.55
37
271
7
36
1.99
0.98
1.0
1.4
—
—
—
0
0
48
383
1.37
0.97
2.7
2.9
7216.1
10756.6
umol/l
0.19
42
321
9
51
1.81
0.96
1.4
2.7
—
—
—
0
0
133
1249
1.48
0.87
5.3
6.3
39.0
40.9
mmol/mol
2.25
124
1150
14
95
1.52
0.67
1.2
1.4
—
—
—
0
0
5
28
1.81
0.66
1.4
1.8
—
—
—
0
0
5
30
1.69
0.62
1.2
1.2
32.6
12.0
u/l
—
5
25
0
21
0.00
0.60
0.0
3.5
—
40.0
—
0
5
59
514
1.24
0.60
1.9
2.3
84.1
78.3
nmol/l
0.63
50
449
15
204
0.71
0.57
1.8
1.2
39.2
45.5
iu/ml
—
6
68
8
55
1.48
0.57
1.0
1.1
—
—
—
0
0
10
141
0.69
0.47
1.8
2.1
9.9
13.3
nmol/l
—
10
133
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
5
34
1.49
0.40
1.6
1.4
—
—
—
0
0
5
35
1.44
0.39
1.4
1.6
—
—
—
0
0
22
180
1.26
0.38
15.5
8.2
—
—
—
0
0
65
708
0.86
0.38
4.5
5.1
2.2
2.7
ug/l
0.33
58
631
13
101
1.31
0.33
8.9
7.3
22.7
24.2
mmol/l
1.00
13
95
89
839
1.14
0.32
3.3
3.2
93.2
54.8
u/l
1.43
83
785
5
75
0.66
0.26
1.6
1.8
—
—
—
0
0
71
669
1.11
0.23
2.3
2.5
—
—
—
0
0
5
40
1.26
0.22
1.4
1.7
—
—
—
0
0
5
41
1.23
0.22
1.4
1.7
—
—
—
0
0
5
42
1.20
0.21
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
17.5
—
0
10
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
4.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
59
565
1.07
0.12
4.5
4.6
25.1
21.0
%
1.10
25
282
15
158
0.94
0.02
2.9
3.8
—
—
—
0
0
29
287
1.01
0.00
1.9
1.7
840.7
1260.7
nmol/l
2.50
21
219
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
5
56
0.89
0.00
1.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
14.3
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
101.5
—
0
6
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
8.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
32.0
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
1.0
2.9
7.0
3225.9
u/ml
—
6
47
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: AF_MAZE – Maze procedure for atrial fibrillation
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).