No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
1065 |
4. Check minimum number of eventsNone |
1065 |
5. Include endpointsNone |
1065 |
6. Filter based on genotype QC (FinnGen only) |
1043 |
Control definitions (FinnGen only)
- Control exclude
- I9_OTHHEART
Extra metadata
- Level in the ICD hierarchy
- 5
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Dronedarone medication
based on the number of shared cases.
Similar with more cases:
- Atrial fibrillation and flutter
- Cardiac arrhythmias
- Other heart diseases
- Other heart diseases, wide
- Cardiovascular diseases (excluding rheumatic etc)
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4159 | 1987 | 2166 |
| Only index persons | 4146 | 1983 | 2163 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.06 |
| Only index persons | 0.08 | 0.07 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 67.74 | 70.95 | 64.81 |
| Only index persons | 67.74 | 70.93 | 64.81 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1043 | 487 | 556 |
| Unadjusted period prevalence (%) | 0.22 | 0.17 | 0.25 |
| Median age at first event (years) | 67.64 | 70.25 | 65.36 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1065
- Matched controls
- 10650
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
576.9
312.9
296
7
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
26.9
307.7
317
165
207
Kela drug reimbursment
Chronic arrhythmias
4503599627370496.0
307.7
1031
5
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
17.6
307.7
665
921
I48
ICD-10 Finland
Atrial fibrillation and flutter
17390.5
307.7
1049
40
B01AA03
ATC
warfarin; systemic
80.8
307.7
850
497
C01BD01
ATC
amiodarone; systemic
1346.0
307.7
359
*
C01BD07
ATC
dronedarone; oral
+∞
307.7
867
*
TFP20
NOMESCO Finland
Cardiodefibrillation
4513.0
307.7
727
5
I50.9
ICD-10 Finland
Heart failure, unspecified
84.7
307.7
321
54
342
Kela drug reimbursment
Dronedarone
+∞
307.7
1065
*
C01BC04
ATC
flecainide; systemic
2460.2
307.7
437
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
992.6
307.7
514
10
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
13.2
307.7
525
730
C07AB07
ATC
bisoprolol; oral
47.4
307.7
1015
3194
K78
ICPC
Atrial fibrillation/flutter
156.1
307.7
467
53
C01AA05
ATC
digoxin; systemic
223.8
307.7
429
32
B01AF02
ATC
apixaban; oral
61.2
307.7
585
208
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
+∞
307.7
305
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
4327.2
307.7
795
7
TFP34
NOMESCO Finland
Electrophysiological investigation
4173.9
307.7
314
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
307.7
702
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
554.5
307.7
337
9
XF404
NOMESCO Finland
Ambulatory ECG
41.5
307.7
408
157
C07AA07
ATC
sotalol; systemic
35.9
287.0
185
62
I50.0
ICD-10 Finland
Congestive heart failure
142.8
273.9
137
11
I48.2
ICD-10 Finland
Chronic atrial fibrillation
+∞
261.6
240
*
I48.1
ICD-10 Finland
Persistent atrial fibrillation
596.8
246.2
235
5
I47.1
ICD-10 Finland
Supraventricular tachycardia
86.0
230.3
122
16
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
898.6
228.1
216
*
TFP35
NOMESCO Finland
Electroanatomical mapping
1273.1
218.7
206
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
11.4
215.9
254
284
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
+∞
214.0
198
*
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
796.3
205.7
196
*
K80
ICPC
Cardiac arrhythmia NOS
11.3
205.5
242
270
C08DA01
ATC
verapamil; systemic
19.7
204.4
166
99
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
+∞
203.9
189
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
58.5
203.7
115
22
I49.5
ICD-10 Finland
Sick sinus syndrome
468.5
200.3
194
5
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
6.1
185.6
480
1255
C03CA01
ATC
furosemide; systemic
5.9
183.1
547
1621
WX404
NOMESCO Finland
Intravenous generell anesthesy
5.8
168.4
453
1212
B01AE07
ATC
dabigatran etexilate; oral
18.2
162.9
136
85
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.0
154.4
805
3638
XF402
NOMESCO Finland
ECG with work load test
6.9
151.8
282
529
AN1
HP
Coronary angiography
6.7
149.1
287
557
B01AF03
ATC
edoxaban; oral
42.7
148.9
90
23
I49.3
ICD-10 Finland
Ventricular premature depolarization
16.7
144.8
126
85
AR6
HP
Catheter ablation of arrhythmia, target: atrial fibrillation
+∞
140.8
132
*
XF400
NOMESCO Finland
ECG with 12 standard connections
5.3
132.2
349
896
C07AB02
ATC
metoprolol; systemic
4.9
130.1
405
1189
201
Kela drug reimbursment
Chronic cardiac insufficiency
27.7
129.2
89
35
C03DA01
ATC
spironolactone; oral
6.5
123.4
236
450
K04
ICPC
Palpitations/awareness of heart
10.5
120.7
141
152
I49.1
ICD-10 Finland
Atrial premature depolarization
21.5
119.7
91
46
AQ2
HP
Electrophysiological electroanatomical examination
+∞
119.0
112
*
I35.0
ICD-10 Finland
Aortic (valve) stenosis
27.3
117.3
81
32
XF640, ,
NOMESCO Finland
19.6
113.4
90
50
AQ1
HP
Conventional electrophysiological examination
+∞
111.4
105
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
210.4
110.8
113
6
B01AF01
ATC
rivaroxaban; oral
5.0
105.1
278
703
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
7.2
105.0
172
278
I25.1
ICD-10 Finland
Atherosclerotic heart disease
4.2
104.4
405
1371
K05
ICPC
Irregular heartbeat other
11.3
90.8
99
96
I50
ICD-10 Finland
Heart failure
36.9
89.4
56
16
I50.1
ICD-10 Finland
Left ventricular failure
921.1
88.0
85
*
C08DB01
ATC
diltiazem; oral
7.5
87.1
134
201
R06.0
ICD-10 Finland
Dyspnoea
3.6
85.9
420
1629
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
+∞
82.4
78
*
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
3.4
80.3
429
1747
AS4
HP
Physiological pacemaker insertion DDD (R)
+∞
79.2
75
*
ZXD05
NOMESCO Finland
Urgent procedure
3.4
78.4
427
1755
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
77.6
370
1399
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
+∞
76.0
72
*
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
+∞
76.0
72
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
3.2
73.9
465
2069
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
24.9
70.3
50
21
SPAT1097
SPAT
Recording of ECG
3.7
69.9
286
972
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
8.3
69.4
95
124
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
6.6
68.6
117
195
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.6
67.3
279
954
R07.4
ICD-10 Finland
Chest pain, unspecified
3.1
66.1
436
1968
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
+∞
65.3
62
*
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
3.3
61.4
298
1118
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
10.8
61.4
68
67
K99
ICPC
Cardiovascular disease other
10.2
60.7
70
73
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
11.9
60.0
62
55
C07AB03
ATC
atenolol; systemic
5.1
59.3
137
302
R00.2
ICD-10 Finland
Palpitations
5.4
58.9
124
252
ZXE00
NOMESCO Finland
One hour or less
2.8
58.9
529
2776
WX892
NOMESCO Finland
Monitored bed care
4.8
55.5
137
319
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
54.9
250
897
R00.1
ICD-10 Finland
Bradycardia, unspecified
9.3
54.5
67
76
C01DA14
ATC
isosorbide mononitrate; oral
3.3
54.5
246
877
N02AJ06
ATC
codeine and paracetamol; systemic
2.7
53.9
549
3031
I20.09
ICD-10 Finland
Unstable angina
5.2
53.8
120
256
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
10.4
53.8
61
62
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
543.9
53.0
52
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
532.9
51.9
51
*
I34.1
ICD-10 Finland
Mitral (valve) prolapse
76.4
51.6
58
8
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
21.9
50.8
38
18
AR5
HP
Catheter ablation of arrhythmia, target: atrial flutter
+∞
49.4
47
*
I47.2
ICD-10 Finland
Ventricular tachycardia
488.8
47.7
47
*
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
12.2
47.5
48
41
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
3.9
47.3
157
455
B01AB05
ATC
enoxaparin; parenteral
2.5
47.0
465
2488
H03BB01
ATC
carbimazole; oral
6.2
46.9
84
146
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.9
46.7
294
1256
K84
ICPC
Heart disease other
8.2
46.4
63
81
I48.3
ICD-10 Finland
Typical atrial flutter
+∞
46.2
44
*
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
234.7
44.3
45
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
85.6
44.2
49
6
I48.4
ICD-10 Finland
Atypical atrial flutter
+∞
44.1
42
*
TFP40
NOMESCO Finland
Ablation treatment for a-v node re-entry activation
+∞
44.1
42
*
C09AA05
ATC
ramipril; oral
2.6
43.8
378
1884
I44.2
ICD-10 Finland
Atrioventricular block, complete
+∞
43.0
41
*
PH3AC
NOMESCO Finland
Flebography of internal organs with X-ray
+∞
41.9
40
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.6
41.5
105
248
R02
ICPC
Shortness of breath/dyspnoea
3.2
41.1
188
668
XF600
NOMESCO Finland
Bloodpressure measurement
4.3
40.3
111
280
I20.99
ICD-10 Finland
Angina pectoris, unspecified
4.1
39.3
116
308
Z3231
NOMESCO Finland
Registered nurse
2.4
38.1
370
1925
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
+∞
37.7
36
*
SPAT1104
SPAT
Monitoring of emergency patient
3.9
37.4
117
324
I42.0
ICD-10 Finland
Dilated cardiomyopathy
+∞
36.7
35
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
369.3
36.2
36
*
81
HP
Angiography of the heart and coronary arteries
4.1
35.7
104
273
Z2221
NOMESCO Finland
Medical doctor
2.4
35.7
346
1789
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
69.1
35.2
40
6
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
6.9
35.1
55
83
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.2
34.7
533
3325
GD1LA
NOMESCO Finland
GD
67.3
34.2
39
6
G47.3
ICD-10 Finland
Sleep apnoea
2.4
34.0
296
1454
PD5BD
NOMESCO Finland
Extensive CT of aorta
10.3
33.8
38
38
TFP32
NOMESCO Finland
Cathetric treatmen of cardiac arrythmia
+∞
33.5
32
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.2
33.4
462
2753
R53
ICD-10 Finland
Malaise and fatigue
2.4
33.3
283
1374
XFE00
NOMESCO Finland
Epicardial ultrasonography
8.4
32.7
43
53
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
74.3
32.0
36
5
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
6.2
31.9
56
95
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
117.0
31.8
34
*
250, ,
Kela drug reimbursment
117.0
31.8
34
*
SPAT1249
SPAT
Treatment-related counselling outside office
2.1
31.4
482
2973
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
3.4
31.0
121
387
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.5
31.0
113
346
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
4.1
30.4
89
234
WX402
NOMESCO Finland
General anaesthesia
2.4
30.0
271
1345
H02AB06
ATC
prednisolone; systemic
2.1
29.5
546
3587
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
29.3
280
1422
SPAT1263
SPAT
Sampling
2.1
29.0
492
3125
A02BC02
ATC
pantoprazole; systemic
2.2
28.3
787
5973
R04.0
ICD-10 Finland
Epistaxis
3.2
28.2
118
394
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
28.1
465
2917
SPAT1260
SPAT
Consultation of another employee
2.4
27.9
242
1175
Z50.0
ICD-10 Finland
Cardiac rehabilitation
10.3
27.5
31
31
R00.0
ICD-10 Finland
Tachycardia, unspecified
5.1
27.2
59
122
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
+∞
27.2
26
*
C01BA03
ATC
disopyramide; systemic
99.3
26.8
29
*
J01DB01
ATC
cefalexin; oral
2.5
26.8
892
7195
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
+∞
26.1
25
*
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
+∞
26.1
25
*
K77
ICPC
Heart failure
24.8
25.8
36
15
K83
ICPC
Heart valve disease NOS
266.8
25.8
26
*
C10AA05
ATC
atorvastatin; oral
2.0
25.7
564
3868
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
34.0
25.7
33
10
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
4.5
25.4
64
150
ZXE20
NOMESCO Finland
More than three and less than five hours
2.4
25.3
195
895
M10.9
ICD-10 Finland
Gout, unspecified
3.3
25.1
103
339
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
+∞
25.1
24
*
R31
ICD-10 Finland
Unspecified haematuria
2.6
25.0
160
672
R2110
NOMESCO Finland
Giving the first information
3.7
24.9
84
244
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.6
24.5
163
698
I10
ICD-10 Finland
Essential (primary) hypertension
2.1
23.9
769
5949
K29
ICPC
Cardiovascular sympt/complt other
3.8
23.7
75
208
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.8
23.6
75
209
SPAT1325
SPAT
Vaccination
1.9
23.5
450
2922
UJF32
NOMESCO Finland
Coloscopy
2.0
23.3
344
2042
N02BE01
ATC
paracetamol; systemic, rectal
3.2
23.3
987
8510
C07AG02
ATC
carvedilol; oral
3.3
23.0
93
303
C01BC03
ATC
propafenone; systemic
+∞
23.0
22
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
22.1
393
2477
M04AA01
ATC
allopurinol; systemic
2.4
22.0
172
791
H11.3
ICD-10 Finland
Conjunctival haemorrhage
3.5
22.0
77
229
SPAT1081
SPAT
Cardiorespiratory global assessment
3.2
22.0
94
317
FPB22
NOMESCO Finland
Transvenous radiofrequency ablation of aberrant pathway or focus of heart
+∞
21.9
21
*
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
+∞
21.9
21
*
R42
ICD-10 Finland
Dizziness and giddiness
2.0
21.4
291
1668
I25.2
ICD-10 Finland
Old myocardial infarction
3.3
21.4
86
279
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
21.2
223
1162
A12BA01
ATC
potassium chloride; oral
4.1
21.1
60
154
C03AA03
ATC
hydrochlorothiazide; oral
2.6
21.1
133
553
I20.00
ICD-10 Finland
Unstable angina
4.7
21.0
49
108
SPAT1251
SPAT
Organisation of medication
4.4
20.9
54
129
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
+∞
20.9
20
*
WX002
NOMESCO Finland
Sedation and analgesia
2.1
20.9
264
1473
FM1CD
NOMESCO Finland
Very extensive CT of heart
214.0
20.6
21
*
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
3.4
20.2
75
232
Z71.8
ICD-10 Finland
Other specified counselling
1.9
20.1
323
1956
S18
ICPC
Laceration/cut
1.8
20.1
568
4106
R03AC02
ATC
salbutamol; inhalant
1.8
20.1
540
3845
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
7.7
20.0
28
37
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
19.9
355
2223
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
19.9
280
1620
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
19.9
19
*
71
HP
Electrophysiological Special Examination
+∞
19.9
19
*
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.2
19.8
204
1051
A10BK01
ATC
dapagliflozin; oral
2.9
19.8
96
348
E05.89
ICD-10 Finland
Other thyrotoxicosis
107.0
19.6
21
*
AP1
HP
Catheterization of the left side of the heart
7.0
19.6
30
44
C10AA01
ATC
simvastatin; oral
1.8
19.6
568
4126
A02BC05
ATC
esomeprazole; systemic
1.8
19.3
460
3148
J01CA04
ATC
amoxicillin; systemic
2.0
19.2
822
6715
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.4
19.2
49
116
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
4.0
19.1
56
147
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
3.1
19.1
83
282
C09DX04
ATC
valsartan and sacubitril; oral
+∞
18.8
18
*
AA1AD
NOMESCO Finland
CT of head and brain
1.9
18.7
333
2076
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.4
18.6
70
218
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.8
18.5
97
366
-69
ICPC
Other reason for encounter NEC
3.7
18.4
60
170
FN1AD
NOMESCO Finland
CT of coronary arteries
6.7
18.4
29
44
R00.8
ICD-10 Finland
Other and unspecified abnormalities of heart beat
8.0
18.3
25
32
XF409
NOMESCO Finland
Other special ECG
44.8
18.3
22
5
C10AX09
ATC
ezetimibe; oral
2.0
18.0
217
1183
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.3
17.8
142
657
WX902
NOMESCO Finland
External defibrillation of heart
+∞
17.8
17
*
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
+∞
17.8
17
*
FK1BT
NOMESCO Finland
Implantation of cardiac pacemaker with X-ray guidance
+∞
17.8
17
*
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
17.8
17
*
A10BK03
ATC
empagliflozin; oral
2.4
17.7
132
592
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
17.5
139
642
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
3.4
17.5
63
191
205
Kela drug reimbursment
Chronic hypertension
1.8
17.5
345
2215
C10AA03
ATC
pravastatin; oral
2.5
17.1
116
498
C09AA04
ATC
perindopril; oral
3.1
17.0
75
257
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.3
17.0
66
210
I20.90
ICD-10 Finland
Angina pectoris, unspecified
3.8
16.9
53
146
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
3.4
16.9
63
195
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.8
16.8
88
332
E66.01
ICD-10 Finland
Obesity due to excess calories
3.0
16.8
79
281
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
+∞
16.7
16
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.7
16.7
91
351
WX872
NOMESCO Finland
Intensive care
3.5
16.6
59
177
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.2
16.6
67
218
C07AB04
ATC
acebutolol; systemic
6.1
16.6
29
49
I25
ICD-10 Finland
Chronic ischaemic heart disease
3.0
16.5
74
256
WVA40
NOMESCO Finland
Initiation and monitoring of intravenous hydration
6.2
16.4
28
46
SPAT1310
SPAT
Counselling related to known health issue
1.8
16.3
373
2492
I49
ICD-10 Finland
Other cardiac arrhythmias
13.0
16.2
28
22
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.3
16.2
130
602
C07AA05
ATC
propranolol; systemic
2.0
16.2
193
1046
R55
ICD-10 Finland
Syncope and collapse
2.3
16.1
135
637
A98
ICPC
Health maint/preventive medicine
5.3
16.0
1044
9624
-34
ICPC
Blood test
4.0
16.0
45
115
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
15.9
434
3040
FN1CB
NOMESCO Finland
Coronary flow reserve measurement with pressure wire
4.3
15.7
41
99
H26.4
ICD-10 Finland
After-cataract
2.2
15.7
154
775
FPE40
NOMESCO Finland
Replacement of transvenous cardiac pacemaker electrode
+∞
15.7
15
*
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
+∞
15.7
15
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
15.6
504
3688
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
15.6
279
1727
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
15.6
720
8374
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
38.7
15.4
19
5
I44.1
ICD-10 Finland
Atrioventricular block, second degree
38.7
15.4
19
5
R07.3
ICD-10 Finland
Other chest pain
2.3
15.3
124
576
J01AA02
ATC
doxycycline; systemic
1.8
15.3
823
6911
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
15.1
348
2320
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.2
15.0
59
189
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.5
15.0
100
426
N05CF01
ATC
zopiclone; oral
1.7
14.9
361
2437
N05BA04
ATC
oxazepam; oral
1.8
14.7
279
1754
FPB32
NOMESCO Finland
Transvenous radiofrequency ablation of pulmonary vein pathway or focus
+∞
14.6
14
*
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
+∞
14.6
14
*
FPB10
NOMESCO Finland
Cryoablation of ectopic heart focus
+∞
14.6
14
*
72
HP
Catheter ablation of arrhythmia
+∞
14.6
14
*
J01FF01
ATC
clindamycin; systemic
1.8
14.5
285
1811
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
15.6
14.4
23
15
K22
ICPC
Risk factor cardiovascular disease
2.6
14.4
89
365
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.8
14.4
72
265
K79
ICPC
Paroxysmal tachycardia
43.1
14.1
17
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
14.1
134
664
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
14.1
717
5844
C08CA13
ATC
lercanidipine; oral
1.9
14.0
187
1050
B01AC04
ATC
clopidogrel; oral
1.9
13.8
209
1224
A46
ICD-10 Finland
Erysipelas
2.0
13.7
162
871
TFP33
NOMESCO Finland
Simple electrophysiological investigation (e.g. ventricular stimulation)
+∞
13.6
13
*
AC4
HP
MVP
+∞
13.6
13
*
73
HP
Initial pacemaker installation
+∞
13.6
13
*
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
+∞
13.6
13
*
C07AB08
ATC
celiprolol; oral
3.5
13.6
47
139
SPAT1153
SPAT
Removal of sutures
1.7
13.3
394
2789
FPW96
NOMESCO Finland
Other operation for arhythmia or disturbance of impulse propagation
40.6
13.2
16
*
PD5AD
NOMESCO Finland
CT of aorta
5.1
12.9
27
54
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
22.9
12.9
18
8
E66.00
ICD-10 Finland
Metabolic syndrome
2.9
12.9
63
229
A13
ICPC
Concern/fear medical treatment
4.8
12.9
29
62
M03BX02
ATC
tizanidine; oral
1.6
12.9
598
4713
C10AA07
ATC
rosuvastatin; oral
1.6
12.8
378
2665
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
5.4
12.8
25
47
FL1AC
NOMESCO Finland
Left cardioangiography
5.9
12.8
23
40
C08CA01
ATC
amlodipine; oral
1.6
12.6
468
3492
M25.5
ICD-10 Finland
Pain in joint
1.7
12.5
320
2172
AS2
HP
Ventricular pacemaker insertion VVI (R)
+∞
12.5
12
*
ARB
HP
Catheter ablation of arrhythmia: Cutiing or modification of the AV node
+∞
12.5
12
*
FFM10
NOMESCO Finland
Occlusion or excision of atrial appendage externally with a closing device
+∞
12.5
12
*
C01B
ATC
ANTIARRHYTHMICS, CLASS I AND III
+∞
12.5
12
*
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
+∞
12.5
12
*
UKC02
NOMESCO Finland
Cystoscopy
1.8
12.5
207
1243
R01AD12
ATC
fluticasone furoate; nasal
1.7
12.5
268
1736
J01FA06
ATC
roxithromycin; oral
1.6
12.4
401
2889
SPAT1285
SPAT
Provision of consultation response
2.7
12.4
70
275
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.9
12.3
164
919
A02BC01
ATC
omeprazole; systemic
1.7
12.2
296
1981
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.9
12.2
35
91
M25.0
ICD-10 Finland
Haemarthrosis
6.1
12.2
21
35
R01AD08
ATC
fluticasone; nasal
1.7
12.1
273
1790
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
12.1
302
2035
AN4
HP
Balloon angioplasty and drug eluding stent
3.1
12.0
51
171
WX722
NOMESCO Finland
PEEP
2.9
12.0
58
210
L15
ICPC
Knee symptom/complaint
1.7
12.0
274
1804
C08CA02
ATC
felodipine; oral
2.1
11.9
118
594
C01BA01
ATC
quinidine; oral
47.2
11.9
14
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
11.8
462
3474
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
11.7
183
1078
M10
ICD-10 Finland
Gout
2.8
11.7
61
230
SPAT1255
SPAT
Intravenous administration of medicine
2.4
11.6
83
365
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.7
11.6
280
1868
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
11.5
159
900
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.9
11.5
148
818
C09CA06
ATC
candesartan; oral
1.7
11.5
256
1670
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
+∞
11.5
11
*
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
+∞
11.5
11
*
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
+∞
11.5
11
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
121.3
11.4
12
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
11.4
111
554
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
11.4
126
661
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
11.3
333
2332
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
11.3
195
1182
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
9.7
11.3
22
23
ZX120
NOMESCO Finland
Intravenous
2.1
11.2
107
530
R05
ICD-10 Finland
Cough
1.7
11.2
224
1417
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
11.2
332
2328
A04
ICPC
Weakness/tiredness general
1.9
11.1
149
835
A11
ICPC
Chest pain NOS
2.2
11.1
101
492
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
11.1
149
836
SPAT1312
SPAT
General health counselling
1.6
10.9
324
2272
-60
ICPC
Result test/procedure
2.4
10.9
74
318
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
3.9
10.8
32
85
SPAT1301
SPAT
No procedures
1.6
10.8
345
2462
FM1BD
NOMESCO Finland
Extensive CT of heart
28.3
10.7
14
5
Q23.11
ICD-10 Finland
Bicuspid aortic valve
60.6
10.6
12
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.2
10.6
97
473
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
10.6
132
722
S80.0
ICD-10 Finland
Contusion of knee
2.4
10.5
71
305
L03
ICPC
Low back symptom/complaint
1.6
10.4
283
1937
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
+∞
10.4
10
*
AH2
HP
Treatment of atrial fibrillation by maze surgery or its modification as the only procedure
+∞
10.4
10
*
AP3
HP
Catheterization of the right and left side of the heart
+∞
10.4
10
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
10.4
68
287
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
10.4
471
3627
C10AA04
ATC
fluvastatin; oral
2.0
10.3
116
612
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
10.3
271
1842
R50.9
ICD-10 Finland
Fever, unspecified
1.9
10.2
145
827
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
10.1
277
1901
SPAT1094
SPAT
Continuous Positive Airway Pressure
4.9
10.0
22
46
K30
ICD-10 Finland
Functional dyspepsia
2.0
10.0
115
611
XF405
NOMESCO Finland
Symptom ECG
16.9
9.9
15
9
K07
ICPC
Swollen ankles/oedema
2.6
9.8
58
233
AN2
HP
Balloon angioplasty, including several vessels
3.0
9.8
42
142
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.8
9.8
29
77
AN3
HP
Balloon angioplasty and metallic stent
3.2
9.8
38
121
G44.2
ICD-10 Finland
Tension-type headache
1.9
9.7
126
697
J01MA02
ATC
ciprofloxacin; systemic
1.5
9.7
410
3096
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.9
9.7
28
73
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.2
9.6
79
369
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.9
9.6
44
155
I44.0
ICD-10 Finland
Atrioventricular block, first degree
11.5
9.6
17
15
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
9.6
606
4976
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
9.5
78
364
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
9.5
673
5653
E66.8
ICD-10 Finland
Other obesity
3.0
9.4
41
140
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
100.9
9.4
10
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
9.4
472
3689
I97.0
ICD-10 Finland
Postcardiotomy syndrome
30.3
9.4
12
*
J01FA10
ATC
azithromycin; systemic
1.5
9.4
502
3975
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
+∞
9.4
9
*
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
+∞
9.4
9
*
AB2
HP
AVR bio, stent
+∞
9.4
9
*
I45.6
ICD-10 Finland
Pre-excitation syndrome
+∞
9.4
9
*
R05
ICPC
Cough
1.6
9.3
243
1641
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.8
9.3
140
812
N19
ICD-10 Finland
Unspecified kidney failure
3.0
9.3
40
136
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
9.3
78
368
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
9.2
365
2713
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.1
9.2
83
403
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.8
9.1
44
160
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
9.0
517
4140
R51.80
ICD-10 Finland
Headache
1.8
9.0
130
745
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
3.5
9.0
30
87
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.5
8.9
56
232
R06.2
ICD-10 Finland
Wheezing
2.8
8.9
45
167
M10.0
ICD-10 Finland
Idiopathic gout
2.8
8.9
43
156
J01FA09
ATC
clarithromycin; systemic
1.6
8.9
282
1993
C07AB12
ATC
nebivolol; oral
3.1
8.9
36
118
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
8.9
269
1881
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.7
8.9
48
185
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
4.5
8.9
21
47
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.0
8.8
38
129
T92
ICPC
Gout
3.6
8.8
29
83
R01AD09
ATC
mometasone; nasal
1.5
8.8
392
2978
A02BC03
ATC
lansoprazole; oral
1.5
8.8
304
2188
-44
ICPC
Preventive immunization/medic
2.0
8.8
105
565
SPAT1211
SPAT
Application of soft bandage
2.0
8.7
100
530
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
8.7
422
3261
J01DC02
ATC
cefuroxime; systemic
2.5
8.7
55
229
AB1
HP
AVR mechanical
50.4
8.7
10
*
R07.2
ICD-10 Finland
Precordial pain
3.4
8.7
31
94
E0000UV, ,
ATC
1.5
8.7
399
3051
R60.0
ICD-10 Finland
Localized oedema
1.8
8.5
136
804
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
8.5
170
1071
K60
ICPC
Cardiovascular, Result test/procedure
7.4
8.5
19
26
I20.01
ICD-10 Finland
Unstable angina
3.0
8.5
37
127
K02.1
ICD-10 Finland
Caries of dentine
1.5
8.4
524
4242
D07AC01
ATC
betamethasone; topical
1.5
8.4
366
2761
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
90.8
8.4
9
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
8.4
60
264
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
3.4
8.4
29
86
K01
ICPC
Heart pain
4.7
8.4
19
41
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
8.4
171
1083
R04.2
ICD-10 Finland
Haemoptysis
2.9
8.3
39
139
FM1GD
NOMESCO Finland
CT of pulmonary arteries and left atrium
+∞
8.3
8
*
42792
ICD-8 Finland
Symptomatic heart disease, Fibrillatio auricularis
+∞
8.3
8
*
FPJ00
NOMESCO Finland
Revision of pacemaker pulse generator or electrode
+∞
8.3
8
*
FPJ02
NOMESCO Finland
Revision of ventricular pacemaker generator
+∞
8.3
8
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
8.3
47
185
SPAT1281
SPAT
Other administrative function
2.0
8.3
87
447
R4110
NOMESCO Finland
Physiotherapy
1.5
8.3
290
2090
H02AB07
ATC
prednisone; oral
1.8
8.3
139
833
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
8.3
138
826
J01MA12
ATC
levofloxacin; systemic
1.6
8.2
190
1242
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
6.6
8.2
20
31
A10
ICPC
Bleeding/haemorrhage NOS
7.6
8.2
18
24
ZXD00
NOMESCO Finland
Emergency procedure
3.2
8.2
32
103
FPH96
NOMESCO Finland
Other removal of cardiac pacemaker or cardioverter-defibrillator
33.6
8.1
10
*
M01AX05
ATC
glucosamine; oral
1.6
8.0
248
1737
M79.6
ICD-10 Finland
Pain in limb
1.5
8.0
406
3152
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
7.9
131
782
SPAT1254
SPAT
Administration of medicine
1.7
7.9
149
923
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.1
7.8
72
352
R06.5
ICD-10 Finland
Mouth breathing
2.0
7.8
89
471
L01
ICPC
Neck symptom/complaint
1.7
7.8
144
888
M54.5
ICD-10 Finland
Low back pain
1.5
7.8
331
2481
61
HP
Catheterization and pressure measurement of the left side of the heart
3.9
7.7
22
57
F2680, ,
NOMESCO Finland
45.3
7.7
9
*
N06AX11
ATC
mirtazapine; oral
1.5
7.7
322
2402
XG466
NOMESCO Finland
Sleep oxymetry
3.2
7.7
29
91
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
4.4
7.7
19
44
R13
ICD-10 Finland
Dysphagia
2.0
7.6
81
418
N05BA01
ATC
diazepam; systemic, rectal
1.8
7.6
131
790
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
7.6
137
837
J20
ICD-10 Finland
Acute bronchitis
1.9
7.6
100
556
I45.9
ICD-10 Finland
Conduction disorder, unspecified
25.2
7.6
10
*
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
3.2
7.6
29
92
K59.1
ICD-10 Finland
Functional diarrhoea
2.2
7.6
62
290
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.6
7.5
175
1144
R52.9
ICD-10 Finland
Pain, unspecified
1.9
7.5
99
550
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.3
7.5
56
252
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.1
7.5
72
359
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
4.4
7.4
18
41
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
2.4
7.4
52
227
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.1
7.4
72
360
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
7.4
75
381
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
13.5
7.4
12
9
SPAT1353
SPAT
Intensive monitoring
13.5
7.4
12
9
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.2
7.4
59
273
SFA10
NOMESCO Finland
One-surface restoration
1.4
7.4
501
4090
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
7.3
251
1794
L17
ICPC
Foot/toe symptom/complaint
1.5
7.3
289
2128
R11
ICD-10 Finland
Nausea and vomiting
2.0
7.3
80
418
FPG40
NOMESCO Finland
Replacement of pulse generator in transvenous cardioverter-defibrillator
+∞
7.3
7
*
42798
ICD-8 Finland
Symptomatic heart disease, Alia arrhytmia definita
+∞
7.3
7
*
21
HP
Aortic Valve Replacement (AVR)
+∞
7.3
7
*
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
+∞
7.3
7
*
I30.9
ICD-10 Finland
Acute pericarditis, unspecified
+∞
7.3
7
*
I42.8
ICD-10 Finland
Other cardiomyopathies
+∞
7.3
7
*
FPE24
NOMESCO Finland
Implantation of biventricular cardiac pacemaker, ventricular electrodes, CRT-P (VVIR)
+∞
7.3
7
*
ATX
HP
Other pacemaker replacement or related action, such as cord removal or replacement
+∞
7.3
7
*
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
+∞
7.3
7
*
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
+∞
7.3
7
*
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
+∞
7.3
7
*
S21
ICPC
Skin texture symptom/complaint
1.6
7.3
161
1040
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
7.2
216
1498
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
7.2
61
289
Z3226
NOMESCO Finland
Physiotherapist
1.6
7.2
185
1239
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
7.2
110
641
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.5
7.2
237
1680
D19
ICPC
Teeth/gum symptom/complaint
1.5
7.2
249
1784
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
7.2
105
604
XG410
NOMESCO Finland
Flow-volume spirometry
2.6
7.2
41
163
C09CA01
ATC
losartan; oral
1.5
7.2
285
2101
F1246, ,
NOMESCO Finland
30.2
7.2
9
*
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.0
7.1
75
387
FM1EE, ,
SPAT
5.7
7.1
19
34
R03BA05
ATC
fluticasone; inhalant
1.6
7.1
155
999
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.5
7.0
44
183
-50
ICPC
Medication/prescr/renewal
2.4
7.0
46
196
S16
ICPC
Bruise/contusion
2.7
6.9
37
142
I95.1
ICD-10 Finland
Orthostatic hypotension
2.5
6.9
44
184
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
5.9
6.9
18
31
X58
ICD-10 Finland
Exposure to other specified factors
1.7
6.9
121
734
A60
ICPC
General and Unspecified, Result test/procedure
2.3
6.9
52
235
J01CA08
ATC
pivmecillinam; oral
1.4
6.9
334
2556
R78
ICPC
Acute bronchitis/bronchiolitis
3.3
6.9
25
77
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
6.8
126
775
K02.0
ICD-10 Finland
Caries limited to enamel
1.7
6.8
128
791
K02
ICPC
Pressure/tightness of heart
2.8
6.8
32
115
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
6.8
109
645
3A064, ,
NOMESCO Finland
40.3
6.8
8
*
A06AC51
ATC
ispaghula, combinations; oral
2.2
6.8
57
270
XF620
NOMESCO Finland
Examination of circulation with color method
16.8
6.7
10
6
B04AB02, ,
ATC
3.4
6.7
23
68
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.7
6.7
34
127
WX780
NOMESCO Finland
Remote monitoring CPAP
2.4
6.7
43
181
N17
ICPC
Vertigo/dizziness
1.7
6.7
133
836
I95.2
ICD-10 Finland
Hypotension due to drugs
7.9
6.6
14
18
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.9
6.6
19
50
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
6.5
71
370
K76
ICPC
Ischaemic heart dis without angina
2.7
6.5
34
129
R06AE07
ATC
cetirizine; oral
1.4
6.5
379
2992
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.5
192
1327
SDA03
NOMESCO Finland
Periodontal treatment
1.4
6.5
354
2762
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.1
6.5
60
295
C02AC05
ATC
moxonidine; oral
2.2
6.4
52
242
K08.80
ICD-10 Finland
Toothache NOS
2.0
6.4
67
344
L13
ICPC
Hip symptom/complaint
1.5
6.4
213
1508
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
70.3
6.4
7
*
I47.0
ICD-10 Finland
Re-entry ventricular arrhythmia
70.3
6.4
7
*
742, ,
NOMESCO Finland
70.3
6.4
7
*
E06.4
ICD-10 Finland
Drug-induced thyroiditis
70.3
6.4
7
*
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.9
6.4
29
102
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
6.4
88
497
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
6.4
110
665
B01AB04
ATC
dalteparin; parenteral
2.2
6.3
51
237
C09CA03
ATC
valsartan; oral
1.8
6.3
101
596
M35.3
ICD-10 Finland
Polymyalgia rheumatica
2.2
6.3
53
251
Z71
ICD-10 Finland
Persons encountering health services for other counselling and medical advice, not elsewhere classified
2.9
6.3
29
103
A10BJ06
ATC
semaglutide; parenteral
2.2
6.3
49
225
Q21.19
ICD-10 Finland
Atrial septal defect NOS
18.1
6.3
9
5
4276B
ICD-9 Finland
Cardiac dysrhythmias, Premature beats[EXTRASYSTOLIA VENTRICULARIS]
+∞
6.3
6
*
FKD10
NOMESCO Finland
Replacement of mitral valve using biological prosthesis
+∞
6.3
6
*
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
+∞
6.3
6
*
4270A
ICD-9 Finland
Cardiac dysrhythmias, Paroxysmal supraventricular tachycardia
+∞
6.3
6
*
AR1
HP
Catheter ablation of arrhythmia, target: AV node reentry activation (AVNRT)
+∞
6.3
6
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
+∞
6.3
6
*
AR2
HP
Catheter ablation of arrhythmia, target: extra pathway (WPW, AVRT, PJRT)
+∞
6.3
6
*
I34.8
ICD-10 Finland
Other nonrheumatic mitral valve disorders
+∞
6.3
6
*
FFM30
NOMESCO Finland
Occlusion of atrial appendage internally by internal suture ligation
+∞
6.3
6
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
6.3
6
*
Z01.2
ICD-10 Finland
Dental examination
1.4
6.2
393
3139
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
6.2
176
1203
Z95.9
ICD-10 Finland
Presence of cardiac and vascular implant and graft, unspecified
26.8
6.2
8
*
ANC
HP
Coronary artery pressure measurement (FFR, fractional flow reserve)
7.1
6.2
14
20
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.8
6.2
84
472
G04CA02
ATC
tamsulosin; oral
1.4
6.2
279
2100
J46
ICD-10 Finland
Status asthmaticus
3.2
6.2
23
72
Z01.9
ICD-10 Finland
Special examination, unspecified
2.0
6.1
64
329
K87
ICPC
Hypertension complicated
2.6
6.1
33
128
T82
ICPC
Obesity
2.8
6.1
30
111
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.7
6.0
31
117
A97
ICPC
No disease
1.5
6.0
185
1288
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
197
18
134.06
307.65
3.8
1.7
0.80
1.04
nmol/l
—
171
5
958
3962
15.11
241.31
55.8
5.8
1.91
1.10
inr
68.86
345
1043
691
2182
7.17
224.94
4.4
1.8
1606.72
491.56
ng/l
12.30
613
1782
668
3185
3.94
103.69
7.0
2.8
21.25
184.62
ng/l
0.65
535
2346
191
358
6.28
100.68
3.7
3.2
4.28
4.46
pmol/l
0.92
172
310
232
591
4.74
85.69
3.5
1.8
252.57
91.89
ng/l
13.02
218
514
392
1501
3.55
81.08
6.0
2.9
168.72
495.89
ng/l
3.08
361
1221
824
5288
3.47
65.83
6.5
3.9
6.57
6.77
mmol/l
2.70
804
4915
327
1300
3.19
61.13
3.0
3.1
0.81
0.81
mmol/l
0.44
299
1208
912
6367
4.01
60.79
5.8
3.7
15.45
14.99
pmol/l
5.74
815
5553
187
567
3.79
53.11
3.6
2.2
4.54
4.36
kpa
0.49
182
554
210
696
3.51
52.09
3.7
2.6
5.90
5.74
kpa
1.45
205
678
721
4628
2.73
50.87
5.8
6.7
13.45
11.41
umol/l
6.30
682
4375
207
693
3.47
50.44
3.6
2.7
1.89
1.91
mmol/l
0.03
188
567
723
4703
2.67
48.67
6.4
5.7
1.20
1.22
mmol/l
6.20
593
3966
942
7076
3.87
48.20
8.9
7.5
75.40
79.68
u/l
3.04
882
6577
675
4280
2.58
47.39
6.0
5.0
1.21
1.22
mmol/l
4.44
602
3819
184
603
3.48
46.12
3.4
2.0
9.57
6.11
ug/l
0.72
167
512
1006
7990
5.68
45.58
7.4
4.5
2.13
2.16
mu/l
0.07
900
7018
259
1064
2.90
44.02
6.3
5.9
104.83
104.10
mmol/l
1.78
259
1064
247
997
2.92
43.30
2.2
2.0
20.93
23.94
%
3.00
214
849
252
1054
2.82
41.15
2.2
2.0
2.42
2.29
g/l
2.80
234
972
265
1148
2.74
40.37
2.2
2.0
12.76
13.43
umol/l
0.80
243
1067
290
1335
2.61
38.95
1.9
1.7
—
—
—
0
0
1033
8737
7.07
34.93
22.9
13.0
23.41
26.88
mg/l
2.54
919
6794
449
2654
2.20
33.08
2.3
2.0
155.75
206.96
u/l
1.77
419
2473
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
81
198
4.35
30.49
3.4
2.2
0.49
0.34
u/ml
0.97
46
98
206
922
2.53
28.47
1.8
1.7
—
—
—
0
0
481
3061
2.04
27.86
3.1
2.4
134.56
162.71
ug/l
2.05
421
2743
421
2576
2.05
26.96
3.4
3.3
33.57
33.71
u/l
0.02
386
2440
160
653
2.71
26.58
4.5
5.3
9.51
8.95
mmol/l
0.45
154
621
421
2590
2.03
26.44
3.5
3.0
0.39
0.47
e6/l
0.34
323
1953
782
6004
2.14
26.06
5.8
4.5
43.70
1888.99
e6/l
—
10
90
200
926
2.43
25.49
7.0
6.2
5.01
5.10
kpa
0.76
190
888
200
927
2.43
25.42
1.8
1.6
—
—
—
0
0
200
927
2.43
25.42
7.0
6.2
11.89
12.61
kpa
0.85
190
887
677
4967
2.00
25.11
7.3
9.5
4.33
4.12
e9/l
1.42
558
4280
504
3348
1.96
25.01
3.5
3.1
—
—
—
0
0
349
2050
2.04
24.54
2.6
2.0
3.39
2.90
mg/l
2.19
293
1685
440
2813
1.96
24.23
3.7
3.1
194.49
75.47
e6/l
0.66
334
2156
195
922
2.36
23.58
7.1
6.3
0.95
0.92
mmol/l
0.04
157
727
372
2268
1.98
23.32
2.9
2.5
6737.57
7209.43
umol/l
0.06
284
1927
330
1932
2.03
23.19
2.6
2.4
3.50
5.00
e6/l
1.95
281
1728
689
5169
1.94
22.92
4.0
3.0
55.02
54.88
u/l
0.02
616
4671
484
3238
1.91
22.90
4.2
3.6
80.11
100.70
e6/l
0.31
345
2300
991
8585
3.22
22.72
24.5
12.8
71.07
76.29
ml/min/173m2
16.09
890
6897
233
1206
2.19
22.62
2.2
1.9
33.30
28.65
s
16.34
228
1168
1054
9529
11.27
22.57
32.5
15.0
139.53
139.68
mmol/l
0.95
1046
9226
989
8570
3.16
22.43
7.6
6.2
40.99
40.20
mmol/mol
2.09
875
7739
573
4077
1.88
22.11
5.7
5.9
25.30
27.65
%
4.97
519
3765
1054
9557
10.96
21.84
33.1
15.1
4.03
3.98
mmol/l
8.02
1046
9231
114
432
2.84
21.68
9.1
7.7
24.81
24.42
mmol/l
0.65
108
427
975
8423
2.86
21.49
5.0
4.1
1.29
1.29
mmol/l
0.11
846
7402
195
958
2.27
21.42
3.3
3.0
—
—
—
0
0
59
153
4.02
20.50
1.3
1.2
—
—
—
0
0
59
153
4.02
20.50
1.3
1.2
—
—
—
0
0
558
4010
1.82
20.15
5.4
5.7
59.39
57.10
%
4.28
504
3704
1048
9555
7.06
19.31
17.1
10.5
26.15
25.42
u/l
0.94
1010
9088
992
8761
2.93
18.75
5.8
4.6
1.35
1.48
mmol/l
18.05
875
7787
997
8847
2.99
18.30
5.7
4.6
4.19
4.62
mmol/l
27.98
883
7931
1003
8934
3.11
18.17
6.1
4.9
6.07
6.03
mmol/l
0.50
858
7899
276
1648
1.91
17.58
1.9
1.6
0.93
1.46
mg/l
2.94
173
1314
355
2322
1.79
16.75
4.6
3.6
62.74
93.37
%
58.36
350
2273
541
3988
1.72
16.72
2.4
2.2
—
—
—
0
0
1011
9107
3.17
16.70
6.7
5.2
2.37
2.70
mmol/l
23.36
895
8113
54
156
3.59
16.11
1.2
1.6
3.56
4.33
iu/l
0.24
12
49
1055
9815
8.98
15.76
36.4
19.9
6.84
6.70
e9/l
1.01
1040
9398
1055
9818
8.94
15.68
37.0
19.9
40.61
39.96
%
3.04
1010
9037
1055
9820
8.92
15.64
36.4
19.9
4.49
4.47
e12/l
0.71
1041
9404
1055
9822
8.89
15.59
36.7
20.0
136.05
135.45
g/l
0.70
1050
9610
1054
9817
8.13
15.29
36.4
19.9
224.84
245.57
e9/l
28.66
1044
9447
395
2725
1.71
15.12
2.7
2.5
61.87
61.47
u/l
0.02
360
2479
797
6638
1.80
15.08
4.9
4.0
13.21
12.72
mm/h
0.41
702
6026
174
938
2.02
14.69
3.0
2.7
6.95
8.69
umol/l
1.15
153
835
185
1031
1.96
14.18
3.8
4.4
1.01
0.99
mmol/l
0.29
163
958
259
1615
1.80
13.96
3.0
2.7
0.82
1.32
e6/l
1.17
155
920
217
1284
1.87
13.86
1.3
1.2
14.04
43.40
iu/ml
9.68
48
385
50
157
3.29
13.14
2.1
3.7
2.03
2.05
mmol/l
0.01
33
112
172
963
1.94
12.94
3.0
4.1
247.11
243.94
u/l
0.12
159
900
533
4091
1.61
12.78
4.3
4.4
35.23
35.37
g/l
0.23
492
3772
284
1863
1.72
12.66
1.9
1.7
1225.86
1130.78
nmol/l
0.69
194
1361
171
966
1.92
12.50
1.8
2.3
1.81
1.73
%
0.49
149
838
147
791
2.00
12.38
2.8
3.5
1.22
1.23
mmol/l
0.48
123
686
241
1525
1.75
12.16
3.4
2.9
2.94
2.36
e6/l
0.30
140
837
546
4254
1.58
12.00
2.5
2.5
—
—
—
0
0
412
3011
1.60
11.87
3.1
3.2
205.57
255.97
mg/l
0.10
243
1847
109
537
2.15
11.62
1.8
1.6
—
—
—
0
0
859
7519
1.74
11.28
28.0
16.1
15.45
15.34
%
0.20
852
7366
412
3049
1.57
11.05
2.9
3.1
6.94
7.51
mmol/l
2.07
314
2514
243
1604
1.67
10.32
1.2
1.2
2.02
1.15
u/ml
0.30
60
385
420
3182
1.53
9.84
3.5
3.8
4.62
4.60
mg/mmol
0.01
233
1969
96
484
2.08
9.63
1.6
1.4
—
—
—
0
0
52
206
2.60
9.09
1.8
1.5
—
—
—
0
0
195
1258
1.67
8.93
1.3
1.2
8.31
17.25
u/ml
1.02
56
416
214
1415
1.64
8.91
1.5
1.4
2.58
2.73
g/l
0.43
100
780
532
4300
1.47
8.76
5.7
5.0
0.00
0.00
estimate
-0.00
133
799
327
2395
1.53
8.75
1.6
1.5
19.94
20.69
nmol/l
0.30
252
1958
519
4181
1.47
8.66
2.3
2.0
89.14
94.10
pmol/l
1.36
250
2089
119
673
1.86
8.58
3.7
2.7
58.48
63.87
ml/min/173m2
0.81
42
260
530
4296
1.47
8.51
4.3
3.7
0.00
0.00
estimate
0.75
142
869
99
531
1.95
8.37
3.8
2.8
5.14
5.05
kpa
0.41
90
506
307
2240
1.52
8.28
2.4
2.4
—
—
—
0
0
423
3312
1.46
7.97
3.1
3.6
2.35
2.36
mmol/l
1.83
346
2825
54
238
2.34
7.56
1.4
1.4
—
—
—
0
0
531
4370
1.43
7.51
4.3
3.7
0.00
0.00
estimate
0.50
123
774
92
503
1.91
7.36
3.8
2.8
1.77
1.46
mmol/l
0.29
65
359
331
2526
1.45
6.93
1.6
1.6
1.33
1.35
mmol/l
0.19
253
2084
39
157
2.54
6.66
2.2
1.7
—
—
—
0
0
41
170
2.47
6.59
1.3
1.5
—
—
—
0
0
134
854
1.65
6.36
1.9
2.0
161.55
138.84
ug/g
0.20
95
662
447
3647
1.39
6.26
2.3
2.1
78.42
80.56
nmol/l
0.84
356
3140
66
342
1.99
6.20
4.5
2.9
24.85
24.65
mmol/l
0.22
60
320
75
408
1.90
6.12
1.2
1.1
244.47
126.09
iu/ml
1.04
19
138
184
1279
1.53
6.04
10.5
6.0
—
—
—
0
0
47
220
2.19
5.77
1.8
1.6
10559.42
13753.17
e6/l
0.26
31
155
65
344
1.95
5.76
1.9
1.8
1.50
2.73
ug/l
0.54
53
309
66
352
1.93
5.72
2.1
1.8
—
—
—
0
0
38
164
2.37
5.64
1.6
2.4
17.14
16.67
%
0.25
14
82
37
158
2.39
5.62
1.3
1.6
—
—
—
0
0
24
82
2.97
5.60
1.4
1.7
—
—
—
0
0
124
806
1.61
5.44
2.6
2.3
41.26
38.55
u/l
0.16
98
695
108
678
1.66
5.44
2.1
2.4
313.54
367.14
nmol/l
1.90
96
623
105
657
1.66
5.36
2.9
2.9
96.40
79.57
ng/l
1.36
84
565
30
119
2.57
5.32
1.4
1.6
—
—
—
0
0
10
13
7.75
4.85
5.1
1.1
—
—
—
0
0
95
598
1.65
4.75
1.8
1.5
—
—
—
0
0
26
102
2.59
4.74
1.4
1.6
—
—
—
0
0
392
3259
1.32
4.45
4.8
4.0
—
—
—
0
0
43
217
2.02
4.41
1.6
1.8
—
—
—
0
0
293
2337
1.35
4.41
4.7
4.0
0.00
0.00
estimate
0.50
128
778
272
2158
1.35
4.22
1.7
1.7
48039647.51
30251560.87
pmol/l
0.14
204
1752
43
225
1.95
4.01
2.8
3.7
3.91
3.86
mmol/l
0.37
43
225
60
355
1.73
3.81
4.4
4.7
1.54
1.51
%
0.11
53
333
6
5
12.06
3.76
1.2
1.0
—
—
—
0
0
242
1918
1.34
3.74
3.4
3.2
2.46
2.46
mmol/l
0.19
207
1697
28
130
2.19
3.60
1.0
1.2
—
—
—
0
0
17
62
2.77
3.60
1.4
1.5
—
—
—
0
0
57
339
1.72
3.57
2.1
1.7
—
—
—
0
0
124
888
1.45
3.50
1.4
1.3
—
—
—
0
0
39
209
1.90
3.43
1.7
1.3
—
—
—
0
0
52
305
1.74
3.43
2.3
2.5
—
—
—
0
0
14
48
2.94
3.30
1.3
1.5
—
—
—
0
0
34
178
1.94
3.22
1.3
2.1
135.24
130.68
g/l
0.37
17
121
24
111
2.19
3.14
1.2
1.5
—
—
—
0
0
24
111
2.19
3.14
1.2
1.5
—
—
—
0
0
21
95
2.23
2.91
1.4
1.5
—
—
—
0
0
106
766
1.43
2.88
2.0
2.7
65.55
66.96
g/l
1.19
93
692
120
891
1.39
2.80
2.5
2.2
0.21
0.21
g/l
0.16
107
843
40
234
1.74
2.72
2.8
2.1
60.46
74.81
ug/min
0.11
22
135
459
4069
1.23
2.70
5.6
5.4
2.95
2.93
ug/l
0.01
398
3653
8
218
0.36
2.67
1.1
1.2
3.36
3.78
mmol/l
—
8
204
17
73
2.35
2.66
1.7
1.2
11326.50
73751.62
e6/l
1.03
12
39
49
307
1.62
2.60
1.8
1.6
36.56
40.79
u/l
0.94
39
270
57
374
1.55
2.51
1.6
1.6
1.36
1.60
g/l
1.34
48
322
33
188
1.78
2.47
4.1
2.0
85.64
89.96
%
0.43
33
182
22
109
2.04
2.47
1.0
1.4
—
—
—
0
0
22
109
2.04
2.47
1.0
1.4
—
—
—
0
0
25
130
1.95
2.47
1.3
1.2
—
—
—
0
0
22
110
2.02
2.42
1.0
1.4
—
—
—
0
0
14
58
2.43
2.37
1.0
1.3
—
—
—
0
0
14
58
2.43
2.37
1.0
1.3
—
—
—
0
0
14
58
2.43
2.37
1.0
1.3
—
—
—
0
0
22
111
2.00
2.37
1.0
1.4
—
—
—
0
0
23
118
1.97
2.36
1.4
1.4
—
—
—
0
0
111
839
1.36
2.35
1.3
1.3
—
—
—
0
0
52
340
1.56
2.34
1.1
1.1
—
—
—
0
0
45
285
1.60
2.31
2.3
3.2
28.55
85.36
mg/l
1.35
34
242
21
106
2.00
2.26
3.4
1.8
4.07
4.00
mmol/l
0.39
21
106
21
106
2.00
2.26
3.4
1.8
106.10
104.84
mmol/l
0.94
21
106
45
287
1.59
2.26
2.3
3.1
46.77
228.85
mg/l
0.48
35
243
15
66
2.29
2.25
2.5
2.8
—
—
—
0
0
41
257
1.62
2.21
1.7
1.4
246.10
267.56
ug/g
0.42
27
140
33
196
1.71
2.17
1.1
1.3
—
—
—
0
0
10
36
2.79
2.14
1.2
1.4
189.00
173.07
mmol/24h
—
10
36
13
55
2.38
2.12
3.2
4.1
295.23
82.89
nmol/l
0.49
13
55
19
95
2.02
2.11
3.4
4.5
—
—
—
0
0
21
109
1.95
2.11
1.0
1.4
—
—
—
0
0
11
250
0.43
2.11
1.1
1.3
739.55
567.66
mg/l
0.40
11
235
281
2422
1.22
2.10
3.5
3.2
0.70
0.80
ug/l
1.11
206
1714
7
20
3.52
2.05
1.3
1.4
—
—
—
0
0
21
111
1.91
2.02
1.0
1.4
—
—
—
0
0
10
38
2.65
2.00
1.2
1.3
—
—
—
0
0
47
315
1.51
1.94
1.6
2.6
1.05
1.51
g/l
0.35
37
274
8
27
2.98
1.94
1.1
1.7
—
—
—
0
0
14
65
2.17
1.88
1.0
1.1
—
—
—
0
0
12
52
2.32
1.88
4.0
1.4
76.50
80.58
umol/l
0.32
12
52
27
159
1.72
1.86
3.0
2.9
55.52
57.37
%
0.29
27
159
37
237
1.58
1.86
1.4
1.6
—
—
—
0
0
15
75
2.01
1.70
1.3
1.6
—
—
—
0
0
15
75
2.01
1.70
1.3
1.6
—
—
—
0
0
41
276
1.50
1.68
1.7
2.5
0.01
0.06
g/l
0.68
35
256
17
90
1.90
1.65
1.3
1.2
—
—
—
0
0
94
735
1.31
1.64
1.9
2.1
12.52
13.19
nmol/l
0.33
86
649
6
20
3.01
1.58
1.8
2.6
—
—
—
0
0
7
26
2.70
1.58
1.0
2.1
692.00
2005.35
u/ml
—
7
26
5
15
3.34
1.52
1.2
1.3
—
—
—
0
0
47
333
1.43
1.52
1.9
2.4
3.13
3.03
g/l
0.23
41
294
19
108
1.77
1.51
1.7
1.5
50.20
58.76
%
—
10
70
25
154
1.64
1.51
2.5
2.8
3.89
4.16
e9/l
0.38
25
154
9
37
2.44
1.48
1.0
1.4
—
—
—
0
0
9
37
2.44
1.48
1.0
1.4
—
—
—
0
0
16
87
1.85
1.46
1.2
1.3
460617.78
109155.20
e6/l
—
9
55
22
133
1.67
1.43
1.7
1.8
34.80
27.61
mg/l
—
5
31
157
1328
1.21
1.42
5.5
4.9
33.42
32.90
%
0.21
95
804
37
255
1.47
1.40
1.4
1.2
—
—
—
0
0
19
111
1.72
1.39
1.2
1.5
—
—
—
0
0
7
29
2.42
1.39
1.4
1.4
—
—
—
0
0
36
249
1.46
1.34
1.1
1.6
—
—
—
0
0
9
44
2.05
1.27
1.7
1.5
—
—
—
0
0
9
44
2.05
1.27
2.0
2.4
—
—
—
0
0
9
44
2.05
1.27
1.7
1.5
—
—
—
0
0
17
102
1.68
1.16
1.4
1.3
—
—
—
0
0
96
790
1.24
1.16
1.5
1.6
1.50
1.62
%
1.29
74
670
13
73
1.79
1.11
1.0
1.5
—
—
—
0
0
36
260
1.40
1.10
1.7
2.5
0.00
0.00
g/l
-0.00
31
241
47
355
1.34
1.10
1.9
2.4
—
—
—
0
0
47
355
1.34
1.10
1.9
2.4
3.65
3.78
g/l
0.30
42
315
47
355
1.34
1.10
1.9
2.4
7.35
7.43
g/l
0.11
42
315
25
169
1.49
1.08
1.2
1.4
—
—
—
0
0
40
296
1.37
1.07
1.7
2.4
35.73
38.04
g/l
1.45
35
256
9
46
1.96
1.03
1.2
1.4
10.69
14.63
umol/l
—
9
41
13
77
1.70
0.95
1.1
1.1
—
79.38
—
0
8
9
51
1.77
0.94
1.7
1.4
—
—
—
0
0
6
28
2.15
0.91
1.2
1.4
—
—
—
0
0
6
28
2.15
0.91
1.0
1.4
—
—
—
0
0
6
28
2.15
0.91
1.0
1.4
—
—
—
0
0
357
3319
1.11
0.91
4.9
4.6
21.47
21.56
%
0.04
185
1766
31
227
1.38
0.91
1.1
1.5
—
—
—
0
0
6
30
2.01
0.87
1.2
1.6
—
—
—
0
0
6
30
2.01
0.87
1.2
1.6
—
—
—
0
0
35
457
0.76
0.86
2.1
1.8
—
—
—
0
0
43
336
1.29
0.84
2.0
2.5
9.56
10.57
g/l
1.12
38
293
8
45
1.78
0.84
1.5
1.5
14.00
14.46
nmol/l
—
8
40
8
47
1.71
0.80
3.0
3.9
—
—
—
0
0
0
25
0.00
0.79
0.0
1.4
—
0.39
—
0
14
23
166
1.39
0.76
1.1
1.2
—
—
—
0
0
13
83
1.57
0.75
1.0
1.1
—
—
—
0
0
7
38
1.85
0.73
1.0
1.1
—
—
—
0
0
12
76
1.59
0.72
1.8
2.2
437.14
651.62
ml
—
7
50
5
27
1.86
0.68
6.2
3.4
238.20
192.11
u/l
—
5
27
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
32
249
1.29
0.68
1.1
1.1
—
—
—
0
0
11
70
1.58
0.65
1.0
1.5
—
—
—
0
0
32
252
1.28
0.63
1.1
1.1
—
—
—
0
0
19
138
1.38
0.62
1.3
1.1
—
—
—
0
0
8
50
1.60
0.61
1.1
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
2.4
—
3.11
—
0
10
10
64
1.57
0.58
1.0
1.0
—
—
—
0
0
27
212
1.28
0.56
1.3
1.5
—
—
—
0
0
6
37
1.63
0.55
1.2
1.2
—
—
—
0
0
6
37
1.63
0.55
1.8
2.2
41683.33
38897.43
ug/l
—
6
37
23
177
1.31
0.55
1.0
1.1
—
—
—
0
0
9
60
1.50
0.54
4.3
2.0
—
—
—
0
0
129
1171
1.12
0.54
3.8
4.5
10.54
29.81
ug/l
1.17
105
974
9
62
1.46
0.53
1.8
1.6
—
—
—
0
0
9
64
1.41
0.51
1.1
1.8
—
—
—
0
0
16
118
1.36
0.50
1.0
1.1
—
—
—
0
0
12
166
0.72
0.48
1.3
1.5
—
—
—
0
0
13
94
1.39
0.46
1.1
1.0
—
—
—
0
0
13
94
1.39
0.46
1.5
1.4
—
—
—
0
0
7
50
1.40
0.45
1.0
1.2
—
—
—
0
0
38
322
1.19
0.43
1.4
1.2
—
—
—
0
0
5
32
1.57
0.42
1.2
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
4.44
—
0
6
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
1.20
—
0
15
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
20
249
0.80
0.40
2.8
1.4
2.55
2.85
mg/l
0.17
14
188
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
9
69
1.31
0.37
1.0
1.1
—
—
—
0
0
18
222
0.81
0.35
5.4
3.3
31.70
29.58
mg/l
—
8
128
6
45
1.34
0.33
1.2
1.0
—
—
—
0
0
6
45
1.34
0.33
3.8
2.4
—
—
—
0
0
6
47
1.28
0.32
1.2
1.4
—
—
—
0
0
11
83
1.33
0.32
2.1
1.1
4.00
3.13
u/ml
—
5
38
7
54
1.30
0.30
1.1
1.7
—
—
—
0
0
5
74
0.67
0.26
1.4
1.0
—
—
—
0
0
6
85
0.70
0.24
1.0
1.1
—
—
—
0
0
5
38
1.32
0.23
1.0
5.4
—
102.56
—
0
9
5
41
1.22
0.22
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
1.2
1.4
—
—
—
0
0
6
49
1.23
0.20
1.3
1.4
1.01
0.94
g/l
—
6
49
195
1886
1.04
0.18
5.0
4.1
1.01
1.02
kg/l
0.87
30
294
6
77
0.78
0.15
1.2
1.2
2.37
1.86
mmol/l
—
6
71
12
140
0.86
0.15
2.3
1.8
13.92
35.14
ug/l
1.56
12
140
8
98
0.81
0.13
1.3
1.4
—
—
—
0
0
5
47
1.06
0.09
1.2
1.3
—
—
—
0
0
5
47
1.06
0.09
1.2
1.3
—
—
—
0
0
10
88
1.14
0.08
2.2
1.1
2.60
1.38
u/ml
—
5
21
26
245
1.06
0.07
1.2
1.2
—
—
—
0
0
43
418
1.03
0.04
2.7
3.6
214.86
3343.29
u/ml
0.71
37
356
18
171
1.05
0.03
1.2
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
5.60
—
0
5
8
79
1.01
0.00
1.4
1.1
95.75
119.07
%
—
8
74
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
6.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.4
—
4.91
—
0
7
8
81
0.99
-0.00
1.3
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.0
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.0
—
—
—
0
0
9
90
1.00
-0.00
1.6
1.3
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.1
—
—
—
0
0
5
53
0.94
-0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.1
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.1
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
87
0.92
-0.00
1.4
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
9.75
—
0
8
6
67
0.89
-0.00
1.0
1.2
—
—
—
0
0
5
53
0.94
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint I9_E_DRONE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_E_DRONE | 0.927 [0.77, 1.11] | 0.406 |
| Birth year | 0.996 [0.99, 1.0] | 0.387 |
During the follow-up period (1.1.1998 — 31.12.2019), 235 out of 1798 females with I9_E_DRONE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_E_DRONE | 0.704 [0.59, 0.84] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 219 out of 2019 males with I9_E_DRONE died.
Mortality risk
Mortality risk for people of age
years, who have I9_E_DRONE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.078% | 0.177% |
| 5 | 0.57% | 0.898% |
| 10 | 1.349% | 2.186% |
| 15 | 2.555% | 4.226% |
| 20 | 4.654% | 7.241% |
Relationships between endpoints
↥Index endpoint: I9_E_DRONE – Dronedarone medication
GWS hits: 6
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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