Ventricular septal defect, a heart condition

Q17_VENTRICULAR_SEPTAL_DEFECT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q21.0
  • Cause of death: ICD-10 Q21.0

2 out of 7 registries used, show all original rules.

886

4. Check minimum number of events

None

886

5. Include endpoints

None

886

6. Filter based on genotype QC (FinnGen only)

843

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 843 521 322
Unadjusted period prevalence (%) 0.17 0.18 0.15
Median age at first event (years) 11.24 12.08 9.88

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
886
Matched controls
8833
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
307.7
342
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
307.7
370
*
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
307.7
528
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
9.3
214.3
336
546
Q21.10
ICD-10 Finland
Persistent ostium secundum
25.9
207.0
150
69
201
Kela drug reimbursment
Chronic cardiac insufficiency
19.8
200.8
165
101
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
12.9
200.1
217
216
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
16.8
193.3
174
127
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
7.1
187.0
429
1026
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
154.7
144
*
31
HP
Congenital heart failure surgery
65.0
129.8
72
12
Q21.19
ICD-10 Finland
Atrial septal defect NOS
50.2
104.6
61
13
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
41.5
101.6
62
16
XF400
NOMESCO Finland
ECG with 12 standard connections
4.8
98.7
294
824
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
12.8
97.7
99
86
B01AA03
ATC
warfarin; systemic
6.4
94.7
179
335
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
507.9
94.1
92
*
Q25.1
ICD-10 Finland
Coarctation of aorta
26.3
93.9
66
27
XF404
NOMESCO Finland
Ambulatory ECG
6.8
92.0
162
282
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.7
91.9
165
293
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
16.9
87.8
75
48
C01AA05
ATC
digoxin; systemic
11.1
87.0
97
97
FM2CE, ,
NOMESCO Finland
7.2
82.2
133
211
61
HP
Catheterization and pressure measurement of the left side of the heart
24.2
78.8
57
25
Q25.0
ICD-10 Finland
Patent ductus arteriosus
15.0
78.1
71
51
C03CA01
ATC
furosemide; systemic
4.5
77.1
233
648
C03DA01
ATC
spironolactone; oral
6.1
76.0
147
279
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.5
72.6
157
330
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
14.7
72.0
66
48
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
9.0
72.0
93
113
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
18.6
69.1
56
32
XF402
NOMESCO Finland
ECG with work load test
6.3
68.9
127
229
XF620
NOMESCO Finland
Examination of circulation with color method
88.1
66.0
73
9
TPH07
NOMESCO Finland
Cathetrisation of artery
4.7
65.9
177
445
XFE00
NOMESCO Finland
Epicardial ultrasonography
13.3
60.9
59
47
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.9
60.8
218
678
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
60.2
434
2078
XF640, ,
NOMESCO Finland
13.5
58.3
56
44
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
19.4
51.9
41
22
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
275.3
51.6
52
*
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
17.3
51.4
43
26
ZXE20
NOMESCO Finland
More than three and less than five hours
3.8
50.6
186
583
XF600
NOMESCO Finland
Bloodpressure measurement
4.0
48.4
156
445
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
47.3
45
*
TFP20
NOMESCO Finland
Cardiodefibrillation
6.8
45.7
74
116
Q23.11
ICD-10 Finland
Bicuspid aortic valve
12.7
45.4
45
37
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
43.9
329
1551
Z2221
NOMESCO Finland
Medical doctor
2.8
43.5
325
1529
I48
ICD-10 Finland
Atrial fibrillation and flutter
4.1
43.5
134
369
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
73.6
43.4
49
7
ZXD10
NOMESCO Finland
Scheduled procedure
2.6
42.4
401
2115
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
225.0
42.2
43
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.7
41.9
354
1765
I50.9
ICD-10 Finland
Heart failure, unspecified
4.9
41.7
99
222
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
6.7
39.6
65
103
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
8.0
38.9
54
71
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
10.0
38.7
45
47
62
HP
Catheterization and pressure measurement of the right side of the heart
65.8
38.4
44
7
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
37.7
36
*
5207
FHL
VSD closure
+∞
36.7
35
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
6.9
36.0
57
87
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.4
35.0
93
228
G04BE03
ATC
sildenafil; oral
13.6
34.9
33
25
C01BD01
ATC
amiodarone; systemic
11.3
34.7
37
34
Z98.8
ICD-10 Finland
Other specified postsurgical states
9.7
33.7
40
43
WX872
NOMESCO Finland
Intensive care
6.4
32.5
55
90
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.3
31.5
135
459
XF622
NOMESCO Finland
Measurement of minute volume of heart
32.0
28.3
37
12
WX882
NOMESCO Finland
High dependency care
3.5
27.8
105
329
Q20.1
ICD-10 Finland
Double outlet right ventricle
77.4
26.9
30
*
WX892
NOMESCO Finland
Monitored bed care
3.4
26.5
105
339
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
24.9
25.8
36
15
C07AB07
ATC
bisoprolol; oral
2.3
25.7
274
1458
I35.0
ICD-10 Finland
Aortic (valve) stenosis
5.6
24.0
46
85
Z3231
NOMESCO Finland
Registered nurse
2.1
23.8
325
1898
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
8.8
23.7
30
35
K84
ICPC
Heart disease other
8.3
22.7
30
37
RS224, ,
NOMESCO Finland
6.6
22.2
36
56
207
Kela drug reimbursment
Chronic arrhythmias
3.5
21.8
80
245
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
20.6
21.8
32
16
ZXE00
NOMESCO Finland
One hour or less
2.0
21.8
380
2409
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
7.3
21.7
32
45
Q21.30
ICD-10 Finland
Tetralogy of Fallot
19.4
21.4
32
17
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
21.3
21.3
31
15
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
8.9
20.7
26
30
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
20.3
235
1276
C07AA07
ATC
sotalol; systemic
6.9
20.0
31
46
I37.0
ICD-10 Finland
Pulmonary valve stenosis
107.1
19.6
21
*
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
7.0
19.5
30
44
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
17.1
19.2
30
18
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
4.2
19.1
52
129
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.7
19.1
109
431
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
15.2
19.0
31
21
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
101.9
18.6
20
*
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
20.5
17.8
26
13
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
67.8
17.8
20
*
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
17.7
17
*
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
+∞
17.7
17
*
90492, ,
NOMESCO Finland
96.7
17.6
19
*
R4110
NOMESCO Finland
Physiotherapy
2.0
17.4
259
1529
I34.1
ICD-10 Finland
Mitral (valve) prolapse
6.2
16.9
29
48
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
15.4
16.7
27
18
I44.2
ICD-10 Finland
Atrioventricular block, complete
6.6
16.7
27
42
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.6
16.4
39
87
I50.0
ICD-10 Finland
Congestive heart failure
4.3
16.3
42
100
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
16.1
199
1096
C07AB02
ATC
metoprolol; systemic
2.4
15.7
114
505
WX402
NOMESCO Finland
General anaesthesia
1.9
15.7
231
1353
FHB00
NOMESCO Finland
Transatrial suture of VSD
+∞
15.6
15
*
Q20.48
ICD-10 Finland
Single ventricle
26.8
15.6
21
8
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
26.8
15.6
21
8
Q21.80
ICD-10 Finland
Communication from left ventricle to right atrium
162.3
15.5
16
*
Q26.1
ICD-10 Finland
Persistent left superior vena cava
38.7
15.4
19
5
ZX199
NOMESCO Finland
Other rote
6.8
15.3
24
36
UGC02
NOMESCO Finland
Rigid bronchoscopy
7.1
15.3
23
33
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.1
15.1
42
106
ZXD05
NOMESCO Finland
Urgent procedure
1.9
14.9
252
1542
5253
FHL
Cardiac lung machine
32.2
14.8
19
6
WX704
NOMESCO Finland
Intubation
2.8
14.7
78
296
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
152.0
14.5
15
*
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
36.6
14.5
18
5
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
43.1
14.1
17
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
24.2
13.8
19
8
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.1
13.7
58
194
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
13.6
13
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
34.5
13.5
17
5
Q22.0
ICD-10 Finland
Pulmonary valve atresia
34.5
13.5
17
5
Q21.21
ICD-10 Finland
Atrioventricular duct
34.5
13.5
17
5
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
13.5
174
969
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.3
13.4
27
52
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
15.3
13.1
21
14
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
11.1
13.0
24
22
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.8
12.8
67
253
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
11.2
12.5
23
21
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
17.6
12.5
19
11
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
+∞
12.5
12
*
FHB96
NOMESCO Finland
Other closure of congenital ventricular septal defect
+∞
12.5
12
*
Q21.8
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
12.5
12
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
131.4
12.4
13
*
C09AA05
ATC
ramipril; oral
2.2
12.2
113
555
I42.0
ICD-10 Finland
Dilated cardiomyopathy
6.1
12.1
21
35
Q25.40
ICD-10 Finland
Aortic hypoplasia
18.3
12.1
18
10
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
27.0
12.1
16
6
C09AA02
ATC
enalapril; systemic
2.3
12.0
94
431
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
11.9
148
811
Z3226
NOMESCO Finland
Physiotherapist
1.8
11.8
193
1159
I50.1
ICD-10 Finland
Left ventricular failure
4.7
11.7
27
59
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
30.4
11.7
15
5
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
23.2
11.6
16
7
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
11.5
11
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
11.5
11
*
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
121.2
11.4
12
*
Q21.1
ICD-10 Finland
Atrial septal defect
121.2
11.4
12
*
7AX01, ,
NOMESCO Finland
12.0
11.3
20
17
ZX120
NOMESCO Finland
Intravenous
2.3
11.3
89
408
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
35.4
11.3
14
*
I49.5
ICD-10 Finland
Sick sinus syndrome
5.2
11.3
23
45
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.6
11.2
21
38
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.6
11.1
63
248
ZX108
NOMESCO Finland
Inhalation
5.3
11.1
22
42
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
10.9
156
896
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
21.7
10.7
15
7
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
10.6
171
1018
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.4
10.6
38
115
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
10.4
162
953
AF1
HP
Surgery of congenital heart defect
111.0
10.4
11
*
51
HP
Other heart surgery
+∞
10.4
10
*
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
+∞
10.4
10
*
Q90.9
ICD-10 Finland
Down syndrome, unspecified
23.6
10.2
14
6
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.9
10.1
152
884
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
40.4
10.0
12
*
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
40.4
10.0
12
*
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.9
9.9
47
168
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
26.3
9.8
13
5
K83
ICPC
Heart valve disease NOS
26.3
9.8
13
5
B01AB05
ATC
enoxaparin; parenteral
1.8
9.8
164
987
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
9.7
267
1839
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.9
9.7
46
165
Q21.3
ICD-10 Finland
Tetralogy of Fallot
55.4
9.6
11
*
Q20.00
ICD-10 Finland
Common arterial trunk
55.4
9.6
11
*
I47.2
ICD-10 Finland
Ventricular tachycardia
4.8
9.5
21
44
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
10.2
9.5
18
18
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
100.8
9.4
10
*
C02KX01
ATC
bosentan; oral
100.8
9.4
10
*
Z50.1
ICD-10 Finland
Other physical therapy
3.1
9.4
38
124
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
9.4
9
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
+∞
9.4
9
*
7451A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[TRANSPOSITIO CORDIS COMPLETA]
+∞
9.4
9
*
R06.0
ICD-10 Finland
Dyspnoea
1.8
9.4
175
1086
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
21.9
9.4
13
6
I48.1
ICD-10 Finland
Persistent atrial fibrillation
5.2
9.3
19
37
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.0
9.2
99
514
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
4.8
9.1
20
42
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
37.0
9.0
11
*
Z2446
NOMESCO Finland
Social worker
1.9
8.9
119
665
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
18.8
8.9
13
7
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
18.8
8.9
13
7
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.0
8.9
38
128
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
12.7
8.9
15
12
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.6
8.8
50
197
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
8.8
59
252
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
8.7
92
474
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.2
8.7
23
56
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
14.2
8.7
14
10
FJD96
NOMESCO Finland
Other operation on right ventricle outlet for congenital or acquired obstruction
50.3
8.7
10
*
Q22.5
ICD-10 Finland
Ebstein anomaly
50.3
8.7
10
*
602
Kela drug reimbursment
Children's severe malnutrition
2.9
8.6
40
142
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
4.8
8.6
19
40
FM1BD
NOMESCO Finland
Extensive CT of heart
16.4
8.6
13
8
I48.4
ICD-10 Finland
Atypical atrial flutter
20.2
8.5
12
6
AP3
HP
Catheterization of the right and left side of the heart
90.6
8.4
9
*
FM1AD
NOMESCO Finland
CT of heart
90.6
8.4
9
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
90.6
8.4
9
*
J01CA04
ATC
amoxicillin; systemic
1.9
8.4
789
7152
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
12.9
8.4
14
11
5609
FHL
Other measure in this category
+∞
8.3
8
*
74646
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium primum
+∞
8.3
8
*
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
+∞
8.3
8
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
7.1
8.3
19
27
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.7
8.2
45
174
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.7
8.2
45
174
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
14.6
8.2
13
9
AP2
HP
Catheterization of the right side of the heart
33.6
8.1
10
*
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
33.6
8.1
10
*
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
11.8
8.1
14
12
WZC30
NOMESCO Finland
Teaching
1.9
7.9
105
587
1EA01, ,
NOMESCO Finland
15.1
7.7
12
8
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
15.1
7.7
12
8
APK
HP
ASD closure
45.2
7.7
9
*
R62.0
ICD-10 Finland
Delayed milestone
2.4
7.6
51
218
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
25.2
7.6
10
*
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
6.2
7.5
19
31
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
6.2
7.5
19
31
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
80.5
7.4
8
*
Q76.48
ICD-10 Finland
Congenital anomalies of other vertebrae, not associated with scoliosis
80.5
7.4
8
*
Q87.06
ICD-10 Finland
Velocardiofacial syndrome
80.5
7.4
8
*
Q22.41
ICD-10 Finland
Tricuspid atresia
80.5
7.4
8
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
80.5
7.4
8
*
FDB20
NOMESCO Finland
Arterial switch operation for other congenital heart defect
80.5
7.4
8
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
80.5
7.4
8
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
80.5
7.4
8
*
R04.0
ICD-10 Finland
Epistaxis
2.4
7.4
52
228
Z31.5
ICD-10 Finland
Genetic counselling
2.0
7.3
76
389
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.1
7.3
29
94
Q21.88
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
7.3
7
*
5501
FHL
Pulmonary artery stenosis
+∞
7.3
7
*
4168X
ICD-9 Finland
Chronic pulmonary heart disease, Other chronic pulmonary heart diseases
+∞
7.3
7
*
42700
ICD-8 Finland
Symptomatic heart disease, Congestive heart failure
+∞
7.3
7
*
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
4.2
7.3
19
46
205
Kela drug reimbursment
Chronic hypertension
1.9
7.3
96
535
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
6.3
7.2
18
29
Q25.3
ICD-10 Finland
Stenosis of aorta
15.8
7.2
11
7
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
30.2
7.1
9
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
20.1
7.1
10
5
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
20.1
7.1
10
5
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.3
7.0
51
227
R50.9
ICD-10 Finland
Fever, unspecified
1.6
6.9
173
1156
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
5.7
6.8
18
32
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
40.2
6.8
8
*
I27.0
ICD-10 Finland
Primary pulmonary hypertension
40.2
6.8
8
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
40.2
6.8
8
*
Q87.14
ICD-10 Finland
Noonan's syndrome
16.8
6.7
10
6
AN1
HP
Coronary angiography
2.5
6.7
42
174
F83
ICD-10 Finland
Mixed specific developmental disorders
2.5
6.7
41
168
TK800
NOMESCO Finland
Hemodialysis
3.9
6.7
19
49
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
22.6
6.7
9
*
GD1LA
NOMESCO Finland
GD
6.5
6.6
16
25
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
7.9
6.6
14
18
I44.1
ICD-10 Finland
Atrioventricular block, second degree
6.9
6.5
15
22
AA1AD
NOMESCO Finland
CT of head and brain
1.7
6.5
131
827
4302
FHL
Tooth patching under general anesthesia
70.1
6.4
7
*
Q17.2
ICD-10 Finland
Microtia
70.1
6.4
7
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
70.1
6.4
7
*
7454X
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[VSD ALIA DEFINITA]
70.1
6.4
7
*
5205
FHL
ASD blockage, secondary defect
70.1
6.4
7
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.8
6.4
99
579
B01AF02
ATC
apixaban; oral
2.3
6.3
45
198
XG460
NOMESCO Finland
Short time oxymetry
5.2
6.3
18
35
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
5.2
6.3
18
35
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.2
6.3
24
76
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.1
6.3
56
271
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
+∞
6.2
6
*
7454E
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[VSD MULTIPLEX]
+∞
6.2
6
*
7456C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[ASD CANALIS ATRIOVENTRICULARIS COMMUNIS]
+∞
6.2
6
*
FM2FN
NOMESCO Finland
Intra cardiac shunt isotope imaging
+∞
6.2
6
*
1201, ,
NOMESCO Finland
26.8
6.2
8
*
Q24.0
ICD-10 Finland
Dextrocardia
26.8
6.2
8
*
K78
ICPC
Atrial fibrillation/flutter
2.7
6.2
31
115
81
HP
Angiography of the heart and coronary arteries
3.1
6.2
25
82
RS220, ,
NOMESCO Finland
3.1
6.2
25
82
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
6.2
41
175
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.6
6.2
20
57
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
6.1
531
6020
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.1
6.1
16
39
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.1
6.0
24
78
UDC00
NOMESCO Finland
Ear microscopy
1.9
6.0
76
417

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
391
1070
5.73
141.29
6.7
4.2
1218.27
981.03
ng/l
0.55
360
883
185
337
6.65
100.89
4.9
4.4
187.60
191.89
ng/l
0.04
172
299
386
2099
2.48
37.02
27.1
8.5
1.49
1.15
inr
5.04
100
639
220
940
2.77
34.39
5.3
3.3
1336.52
670.36
ng/l
1.97
178
586
31
27
11.83
30.06
5.3
7.0
—
—
—
0
0
31
28
11.40
29.36
5.4
6.8
—
—
—
0
0
527
3589
2.14
26.41
4.4
2.9
—
—
—
0
0
202
982
2.36
23.17
9.7
9.2
0.83
0.82
mmol/l
0.58
193
937
300
1769
2.04
20.87
8.8
6.7
73.90
89.79
%
17.65
294
1738
280
1627
2.05
20.16
2.9
2.8
—
—
—
0
0
103
406
2.73
18.15
5.7
6.9
23.93
22.98
s
0.67
98
387
320
2014
1.91
17.88
3.0
2.9
—
—
—
0
0
26
18
14.80
15.88
2.5
2.0
—
—
—
0
0
167
866
2.14
15.87
3.4
2.7
20.54
22.52
%
1.32
152
792
56
169
3.46
15.62
10.9
16.7
—
—
—
0
0
75
275
2.88
15.10
28.7
14.4
—
—
—
0
0
80
308
2.75
14.71
2.3
2.4
17.99
6.53
ug/l
2.78
68
270
412
2936
1.75
14.49
3.4
3.0
—
—
—
0
0
113
521
2.33
14.23
21.4
10.9
0.34
0.51
mmol/l
0.20
99
415
169
928
2.01
13.62
3.4
2.6
2.48
2.47
g/l
0.12
161
863
137
700
2.13
13.40
11.1
10.1
105.73
104.96
mmol/l
1.22
137
700
252
1590
1.81
13.25
3.9
3.0
46.60
40.36
ng/l
0.21
155
840
179
1019
1.94
12.96
3.5
2.6
12.86
13.78
umol/l
1.06
171
961
90
410
2.32
11.61
17.7
10.7
123.28
121.92
g/l
0.21
90
402
71
294
2.53
11.28
8.4
11.5
0.73
0.63
%
1.56
71
294
147
819
1.95
11.23
2.5
1.9
—
—
—
0
0
191
1159
1.82
11.20
11.4
10.2
1.30
1.26
mmol/l
0.86
186
1098
173
1024
1.85
10.97
18.4
11.1
—
—
—
0
0
394
2926
1.62
10.83
9.6
7.1
20.21
17.29
umol/l
0.93
362
2735
178
1072
1.82
10.65
12.7
9.7
7.41
7.41
ph
0.28
11
48
35
103
3.49
10.18
10.5
24.2
11.95
11.49
%
0.47
35
103
482
3810
1.57
9.82
11.2
6.5
6.09
6.25
mmol/l
1.14
455
3508
420
3230
1.56
9.56
13.8
10.4
1.22
1.22
mmol/l
1.40
372
2889
154
918
1.81
9.45
12.7
9.9
—
—
—
0
0
398
3030
1.56
9.44
17.7
10.7
1.21
1.23
mmol/l
3.07
380
2829
760
6756
1.85
9.40
22.6
13.3
139.27
139.51
mmol/l
2.20
747
6553
213
1401
1.68
9.22
4.6
4.2
—
—
—
0
0
759
6761
1.83
9.10
22.7
13.3
3.97
3.94
mmol/l
1.81
745
6534
328
2407
1.57
9.05
7.9
6.5
36.62
37.10
g/l
0.73
312
2272
203
1347
1.65
8.41
4.0
3.4
1.42
1.39
mg/l
0.03
152
992
75
364
2.15
8.31
10.0
11.3
133.24
127.84
g/l
0.94
75
359
24
63
3.88
8.24
4.1
4.0
1.00
3.17
%
—
6
27
190
1248
1.66
8.17
4.4
3.1
—
—
—
0
0
806
7376
1.99
8.07
16.1
9.7
—
—
—
0
0
48
205
2.41
7.20
1.5
2.3
1.29
1.27
g/l
0.05
35
180
164
1071
1.65
7.15
8.9
9.7
5.07
4.99
kpa
0.24
159
1047
171
1130
1.63
7.11
9.4
9.7
1.09
1.10
mmol/l
0.01
146
899
171
1135
1.62
6.97
9.3
9.7
5.89
5.77
kpa
0.96
166
1110
35
130
2.75
6.96
4.4
6.2
—
—
—
0
0
283
2139
1.47
6.30
4.9
4.0
34.70
32.44
u/l
0.28
276
2042
241
1785
1.48
5.89
2.9
2.7
3.23
2.74
mg/l
1.14
217
1570
34
136
2.55
5.89
4.8
4.1
—
—
—
0
0
30
113
2.70
5.84
3.0
3.1
17.11
17.05
%
0.03
20
68
113
709
1.68
5.71
1.9
1.6
—
—
—
0
0
299
2347
1.41
5.24
1.7
1.6
—
—
—
0
0
23
80
2.92
5.19
4.3
4.2
—
—
—
0
0
732
6702
1.51
5.11
23.2
15.4
14.17
13.92
%
0.89
726
6602
12
19
6.37
5.07
1.0
1.3
—
—
—
0
0
525
4537
1.38
5.06
8.0
6.5
96.66
97.13
u/l
0.05
500
4256
35
153
2.33
5.05
2.2
2.7
133.18
132.61
g/l
0.05
28
120
29
116
2.54
5.05
6.7
5.0
2.13
1.88
mmol/l
0.21
15
61
198
1461
1.45
4.83
2.9
2.2
429.44
282.29
u/l
0.67
188
1390
434
3666
1.35
4.69
10.6
10.6
0.00
0.00
e9/l
0.44
353
2855
100
641
1.63
4.66
1.3
1.2
—
—
—
0
0
44
219
2.06
4.65
4.0
3.2
—
—
—
0
0
421
3553
1.35
4.52
3.5
3.1
77.34
76.07
ug/l
0.08
402
3325
62
351
1.82
4.51
2.5
3.0
65.65
65.88
g/l
0.06
56
325
86
535
1.67
4.50
5.8
7.1
73.18
58.80
ng/l
0.95
78
507
24
93
2.62
4.47
4.2
3.8
—
—
—
0
0
127
877
1.52
4.29
2.1
1.7
—
—
—
0
0
461
3970
1.33
4.20
7.6
8.2
0.04
0.04
e9/l
0.12
400
3355
461
3970
1.33
4.20
7.6
8.2
0.59
0.56
e9/l
1.41
401
3358
437
3744
1.32
4.09
8.2
8.7
—
—
—
0
0
78
486
1.66
4.07
3.8
5.3
0.87
0.85
%
0.02
26
175
73
447
1.68
4.07
3.5
4.9
0.74
0.48
%
0.57
25
149
14
36
3.92
3.99
2.0
1.2
—
—
—
0
0
72
443
1.68
3.95
3.8
5.5
0.05
0.06
%
0.09
20
125
63
374
1.73
3.93
4.5
4.4
1.22
1.23
mmol/l
0.43
56
322
235
1855
1.36
3.79
3.1
3.0
2.38
2.38
mmol/l
0.03
217
1663
470
4097
1.31
3.76
8.3
8.8
0.20
0.20
e9/l
0.21
410
3523
12
29
4.17
3.70
2.0
1.2
—
—
—
0
0
27
122
2.24
3.67
1.5
1.7
9.92
10.28
g/l
0.21
21
113
73
461
1.63
3.64
3.8
5.5
0.05
0.09
%
0.35
20
148
34
631
0.52
3.57
1.2
1.2
—
52.49
—
0
7
205
1599
1.36
3.55
5.1
3.7
7.40
7.40
ph
0.21
45
274
768
7220
1.45
3.53
17.7
11.7
24.75
21.68
mg/l
1.87
614
5298
427
3695
1.29
3.53
8.1
8.4
0.62
0.64
%
0.38
413
3500
467
4102
1.29
3.38
7.7
8.1
1.91
2.21
e9/l
6.91
413
3573
21
90
2.36
3.24
2.5
1.7
14365.81
19200.75
e6/l
0.21
16
68
7
11
6.38
3.18
1.0
1.1
—
—
—
0
0
242
1964
1.31
3.17
4.4
3.8
0.71
0.30
e6/l
0.79
184
1455
13
40
3.27
3.13
1.5
1.3
—
—
—
0
0
42
241
1.77
3.00
8.7
6.0
—
—
—
0
0
5
5
10.02
2.97
1.8
1.4
—
—
—
0
0
495
4430
1.26
2.88
10.4
10.5
3.92
3.74
e9/l
1.03
431
3747
6
9
6.68
2.86
16.3
17.1
—
—
—
0
0
239
1966
1.29
2.79
4.2
3.7
—
—
—
0
0
256
2125
1.28
2.79
4.8
3.9
28.85
66.18
e6/l
0.58
198
1590
434
3836
1.25
2.77
8.4
8.4
8.92
8.26
%
5.38
420
3643
72
1033
0.67
2.76
1.2
1.2
—
—
—
0
0
23
112
2.08
2.67
1.3
1.6
37.54
39.13
g/l
0.44
17
104
257
2147
1.27
2.64
7.7
8.5
—
—
—
0
0
430
3811
1.24
2.64
8.2
8.3
3.01
3.01
%
0.02
416
3614
847
8200
1.68
2.60
28.9
17.6
39.76
39.97
%
0.46
818
7816
847
8208
1.65
2.48
26.1
17.0
88.64
88.23
fl
1.58
840
8097
16
69
2.34
2.48
48.8
42.2
7.36
6.43
ug/l
1.31
16
60
36
210
1.74
2.47
1.6
2.1
—
—
—
0
0
8
21
3.82
2.46
1.1
1.4
187.00
149.26
mmol/24h
—
8
21
847
8210
1.65
2.45
26.1
17.0
29.63
29.55
pg
0.65
840
8100
12
45
2.68
2.44
5.8
2.8
—
—
—
0
0
112
842
1.37
2.44
4.2
5.9
1.63
1.51
%
0.43
103
785
847
8211
1.65
2.44
26.2
17.1
4.55
4.57
e12/l
0.47
826
7893
847
8213
1.64
2.41
26.2
17.1
6.91
6.88
e9/l
0.10
825
7898
847
8215
1.63
2.38
27.4
17.3
133.66
134.35
g/l
0.60
841
8105
42
259
1.65
2.37
8.2
6.1
24.91
24.29
mmol/l
0.60
42
253
846
8204
1.62
2.36
26.2
17.1
247.96
263.85
e9/l
9.93
828
7911
10
33
3.04
2.35
1.1
1.5
—
—
—
0
0
444
3983
1.22
2.33
8.2
8.2
29.17
33.07
%
9.85
429
3804
9
28
3.23
2.30
1.9
1.5
—
—
—
0
0
16
72
2.24
2.27
2.6
1.6
—
—
—
0
0
174
1412
1.28
2.24
4.3
3.0
6.02
7.16
e6/l
0.50
156
1246
8
24
3.34
2.17
1.4
2.0
—
—
—
0
0
214
2518
0.80
2.17
1.5
1.6
1.39
2.86
u/ml
1.08
53
533
293
2540
1.22
2.10
5.4
4.5
67.93
63.69
e6/l
0.08
203
1688
30
175
1.73
2.10
3.1
1.9
3.45
6.19
iu/l
—
9
63
169
1380
1.27
2.07
4.2
3.1
567.48
568.80
mosm/kgh2o
0.02
151
1181
110
848
1.33
2.06
7.7
5.6
9.92
7.36
umol/l
0.59
97
708
434
3928
1.20
1.96
8.0
8.0
55.12
51.99
%
5.77
420
3753
22
120
1.85
1.92
10.7
9.5
1.22
1.17
mmol/l
0.12
22
106
200
2341
0.81
1.90
1.6
1.6
1.84
1.83
g/l
0.03
133
1272
13
58
2.25
1.90
2.8
1.4
—
—
—
0
0
23
128
1.81
1.89
1.4
1.3
—
—
—
0
0
476
4368
1.19
1.77
5.0
4.0
746.22
341.57
e6/l
—
9
51
82
621
1.35
1.75
1.9
2.4
3262.08
6503.87
u/l
0.88
24
232
18
95
1.91
1.75
7.6
5.3
—
—
—
0
0
28
170
1.66
1.74
3.8
3.7
1.20
1.52
e9/l
1.35
22
126
150
1234
1.26
1.73
3.3
3.4
0.59
0.85
e6/l
1.14
85
698
147
1208
1.26
1.71
3.5
3.5
1.98
2.62
e6/l
0.63
80
675
19
103
1.86
1.71
1.0
1.0
166.74
162.78
g/l
0.39
19
103
52
718
0.70
1.68
1.2
1.2
—
—
—
0
0
29
180
1.63
1.66
6.5
6.1
—
—
—
0
0
23
134
1.73
1.66
2.9
2.6
—
—
—
0
0
6
19
3.16
1.66
1.3
5.0
—
—
—
0
0
25
151
1.67
1.59
10.0
8.8
0.91
0.88
%
0.16
25
142
21
121
1.75
1.58
1.1
1.2
3.85
4.33
u/ml
0.10
13
58
11
50
2.21
1.56
3.6
2.7
4.13
4.03
mmol/l
0.31
11
50
42
289
1.47
1.56
2.5
2.1
137.40
94.08
u/ml
—
5
32
6
21
2.86
1.50
2.8
2.6
—
—
—
0
0
88
692
1.30
1.48
1.3
1.4
160.62
282.37
u/ml
1.44
82
643
47
336
1.42
1.45
2.9
4.0
10.18
20.86
ug/l
0.33
34
258
101
813
1.27
1.42
1.9
2.4
2.43
2.43
mmol/l
0.05
88
690
143
1198
1.23
1.41
4.5
3.6
3546.58
4351.35
umol/l
0.09
132
1069
25
384
0.64
1.41
1.0
1.1
—
—
—
0
0
52
381
1.38
1.40
1.7
1.5
—
—
—
0
0
196
1696
1.20
1.39
3.3
2.7
58.41
59.74
u/l
0.13
177
1585
25
158
1.59
1.37
3.9
3.7
0.37
0.17
e9/l
1.34
18
113
493
4604
1.15
1.31
4.8
4.1
—
—
—
0
0
9
172
0.52
1.30
2.3
1.2
—
—
—
0
0
9
43
2.10
1.30
1.0
1.2
—
—
—
0
0
144
1675
0.83
1.27
1.6
1.7
—
—
—
0
0
17
100
1.71
1.23
1.1
1.1
—
—
—
0
0
736
7101
1.20
1.22
11.7
9.2
25.23
26.28
u/l
0.83
716
6853
10
49
2.05
1.21
3.9
2.7
104.00
105.88
mmol/l
—
10
49
10
49
2.05
1.21
3.9
2.7
—
—
—
0
0
8
37
2.17
1.21
1.8
2.3
—
—
—
0
0
41
297
1.39
1.20
2.6
2.0
—
—
—
0
0
55
707
0.76
1.17
2.1
1.8
—
—
—
0
0
55
707
0.76
1.17
2.3
1.9
—
—
—
0
0
239
2140
1.16
1.12
2.0
1.9
—
—
—
0
0
10
51
1.97
1.10
1.1
7.1
—
—
—
0
0
191
1684
1.17
1.09
4.4
3.5
0.00
0.00
estimate
0.50
64
611
24
160
1.51
1.09
3.9
3.6
415.61
552.44
e6/l
1.30
18
113
52
665
0.77
1.08
2.4
1.9
—
—
—
0
0
14
81
1.73
1.08
1.3
1.4
—
—
—
0
0
43
561
0.75
1.04
2.7
1.9
—
—
—
0
0
46
350
1.33
1.03
1.5
1.3
—
—
—
0
0
57
714
0.78
1.02
2.4
1.9
—
—
—
0
0
11
60
1.84
1.02
2.5
4.2
—
—
—
0
0
13
75
1.74
1.02
16.5
12.8
11.54
10.84
mmol/l
0.54
13
67
57
712
0.78
1.00
2.3
1.8
—
—
—
0
0
73
593
1.25
1.00
3.6
4.7
68.70
66.78
e9/l
0.13
49
398
13
76
1.72
0.98
16.5
12.6
105.92
105.51
mmol/l
0.16
13
68
25
173
1.45
0.97
1.2
1.2
—
—
—
0
0
23
157
1.47
0.95
10.0
8.7
1.46
1.55
%
0.27
23
146
6
28
2.14
0.91
1.3
1.2
—
—
—
0
0
6
28
2.14
0.91
1.3
1.3
—
—
—
0
0
86
720
1.21
0.91
3.5
3.6
9.28
9.20
g/l
0.06
81
678
112
1288
0.85
0.89
2.6
2.9
99.63
106.11
ug/g
0.11
95
1016
201
1808
1.14
0.88
3.4
2.5
—
—
—
0
0
10
56
1.79
0.87
2.6
2.4
31.90
32.54
pg
—
10
56
6
30
2.00
0.87
1.2
1.2
—
—
—
0
0
10
57
1.76
0.83
1.0
1.2
—
—
—
0
0
10
57
1.76
0.83
1.0
1.0
—
—
—
0
0
51
626
0.80
0.80
2.6
2.4
32.29
29.44
u/l
0.32
45
515
44
348
1.27
0.78
1.4
1.3
158.25
257.80
miu/ml
1.04
16
167
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
0
26
0.00
0.78
0.0
1.4
—
—
—
0
0
11
174
0.63
0.78
1.2
1.1
94.60
202.12
iu/ml
—
5
53
20
140
1.43
0.76
1.6
1.5
—
—
—
0
0
17
242
0.69
0.74
1.0
1.1
0.06
0.69
u/ml
—
7
116
7
38
1.84
0.73
2.7
4.8
—
—
—
0
0
21
150
1.41
0.73
2.8
2.0
5.62
3.32
ug/l
0.22
21
132
566
5440
1.10
0.72
4.4
3.7
14.67
14.48
pmol/l
1.08
517
4958
17
240
0.70
0.71
2.0
3.8
336.18
421.61
mg/l
0.88
17
232
45
362
1.25
0.71
1.7
1.9
287.46
193.55
u/ml
1.04
26
178
55
453
1.22
0.71
2.1
1.6
—
—
—
0
0
20
143
1.40
0.69
3.7
4.2
53.65
53.79
%
0.01
20
143
23
169
1.37
0.69
9.3
8.0
—
—
—
0
0
87
994
0.86
0.67
1.3
1.2
2.58
9.67
u/ml
2.17
37
356
33
258
1.29
0.66
5.9
4.4
30.77
22.12
nmol/l
2.03
33
250
5
28
1.78
0.66
4.0
2.8
—
—
—
0
0
20
145
1.38
0.65
3.4
4.0
489.09
380.97
e6/l
0.32
11
93
83
719
1.17
0.64
1.4
1.3
—
—
—
0
0
48
396
1.22
0.63
1.1
1.2
—
—
—
0
0
123
1099
1.13
0.62
1.6
1.4
18.29
19.97
nmol/l
0.78
106
939
0
22
0.00
0.59
0.0
1.4
—
125.36
—
0
22
19
253
0.74
0.59
1.0
1.1
3.37
8.93
u/ml
2.83
14
147
0
23
0.00
0.58
0.0
1.2
—
88.84
—
0
15
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
10
64
1.56
0.58
3.0
3.8
5962.85
486.66
u/ml
—
10
59
71
614
1.17
0.57
1.3
1.3
154.46
146.81
iu/ml
0.07
32
233
21
274
0.76
0.57
1.1
1.1
7.13
6.98
u/ml
0.02
16
175
125
1374
0.89
0.56
1.9
1.8
—
—
—
0
0
11
73
1.51
0.55
1.1
1.2
0.51
0.49
nmol/l
0.09
11
67
6
37
1.62
0.55
1.8
1.1
—
—
—
0
0
6
37
1.62
0.55
1.8
1.1
—
—
—
0
0
6
37
1.62
0.55
1.8
1.1
—
—
—
0
0
6
37
1.62
0.55
1.0
1.1
984.83
1313.59
miu/ml
—
6
37
27
338
0.79
0.55
3.0
2.3
—
—
—
0
0
101
901
1.13
0.54
1.5
1.6
488.23
17503659.03
pmol/l
0.80
84
777
35
285
1.23
0.53
2.3
2.5
22.08
31.43
u/ml
0.81
35
272
9
62
1.45
0.53
1.1
1.2
—
—
—
0
0
15
108
1.39
0.52
1.4
2.2
—
—
—
0
0
294
2779
1.08
0.51
3.2
3.0
73.22
71.84
nmol/l
0.37
267
2564
210
1957
1.09
0.51
1.9
1.8
94.33
97.48
pmol/l
0.42
128
1000
126
1145
1.11
0.50
3.8
3.4
83.90
250.58
mg/l
0.97
91
797
202
2149
0.92
0.48
2.2
2.1
—
—
—
0
0
7
46
1.52
0.48
2.0
2.0
—
—
—
0
0
179
1661
1.09
0.48
3.7
3.4
—
—
—
0
0
165
1762
0.92
0.43
4.3
2.9
—
—
—
0
0
9
127
0.70
0.43
3.1
4.1
—
—
—
0
0
75
668
1.13
0.43
1.5
1.5
—
—
—
0
0
130
1196
1.10
0.42
4.3
4.0
15.50
23.69
mg/mmol
0.21
92
802
6
91
0.66
0.42
2.2
2.4
1.57
2.33
mmol/l
—
6
68
6
91
0.66
0.42
1.0
1.0
—
—
—
0
0
82
736
1.12
0.42
1.6
1.6
1134.47
1172.61
nmol/l
0.16
58
553
5
32
1.56
0.42
1.8
1.1
—
—
—
0
0
8
57
1.40
0.42
1.0
1.7
—
—
—
0
0
12
161
0.74
0.42
2.8
5.0
—
—
—
0
0
23
282
0.81
0.42
1.4
1.5
—
—
—
0
0
10
70
1.43
0.41
1.1
1.2
—
—
—
0
0
8
59
1.35
0.41
1.6
1.4
—
—
—
0
0
8
59
1.35
0.41
1.3
1.5
15.00
9.56
umol/l
—
8
59
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
36
420
0.85
0.40
1.1
1.2
—
—
—
0
0
18
141
1.28
0.39
3.1
4.0
4.23
3.84
e9/l
0.25
18
141
63
559
1.13
0.39
4.3
3.5
—
—
—
0
0
29
344
0.84
0.39
1.8
1.5
—
—
—
0
0
18
224
0.80
0.38
1.9
3.8
3.55
3.48
mmol/l
0.15
18
210
23
278
0.82
0.37
1.4
1.4
—
—
—
0
0
45
392
1.15
0.37
3.5
3.5
—
—
—
0
0
8
115
0.69
0.37
11.5
3.0
—
—
—
0
0
23
277
0.82
0.36
1.4
1.4
—
—
—
0
0
87
794
1.10
0.35
3.5
2.5
383.25
354.48
nmol/l
0.47
81
750
49
433
1.14
0.34
1.2
1.2
—
26.85
—
0
19
11
83
1.33
0.31
2.7
1.8
137.27
136.48
ng/l
0.01
11
77
7
52
1.34
0.31
11.1
12.4
899.29
831.54
nmol/l
—
7
52
7
96
0.72
0.31
1.3
1.3
3.27
4.82
u/ml
—
7
91
7
97
0.72
0.31
1.4
1.5
—
—
—
0
0
8
107
0.74
0.29
1.6
1.8
2.53
3.76
u/ml
—
8
107
117
1096
1.07
0.28
1.8
1.6
—
—
—
0
0
533
5212
1.05
0.28
3.6
3.3
1.20
1.21
mmol/l
0.03
499
4876
9
116
0.77
0.27
1.2
1.4
—
—
—
0
0
88
816
1.08
0.27
3.8
4.2
1.36
2.34
ug/l
1.58
78
734
42
467
0.89
0.27
2.0
2.3
3.74
4.87
e9/l
1.22
34
421
14
171
0.81
0.27
2.6
2.2
—
—
—
0
0
24
205
1.17
0.27
1.1
1.2
—
—
—
0
0
8
67
1.19
0.26
1.1
1.1
—
—
—
0
0
43
476
0.90
0.26
2.9
2.5
—
—
—
0
0
142
1489
0.94
0.25
4.1
3.2
1.01
1.02
kg/l
0.45
18
225
19
223
0.85
0.25
1.0
1.1
—
—
—
0
0
283
2733
1.05
0.25
3.7
3.1
6.34
6.09
ph
0.72
22
275
21
244
0.85
0.25
1.6
1.7
—
—
—
0
0
174
1812
0.95
0.25
4.2
3.9
7.24
8.12
mmol/l
1.53
160
1622
9
76
1.18
0.24
4.3
4.7
23.70
21.87
ug/l
—
9
76
51
464
1.10
0.24
2.5
2.0
8.77
7.39
u/l
0.32
36
315
177
1691
1.05
0.24
1.9
1.7
—
—
—
0
0
18
211
0.85
0.24
2.2
4.2
—
—
—
0
0
11
88
1.25
0.22
1.4
1.5
—
—
—
0
0
5
41
1.22
0.22
4.8
3.7
152.60
86.97
u/ml
—
5
41
62
665
0.92
0.21
1.7
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
4.8
—
138.73
—
0
11
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
8
105
0.76
0.21
1.3
1.7
295.50
291.61
mosm/kgh2o
—
8
72
47
430
1.09
0.21
3.1
4.3
—
—
—
0
0
0
13
0.00
0.21
0.0
2.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
2.0
1.2
172.10
213.90
pmol/l
—
6
48
6
53
1.13
0.18
1.0
1.2
—
—
—
0
0
24
213
1.13
0.18
1.9
1.8
—
—
—
0
0
5
69
0.72
0.17
1.2
1.8
—
—
—
0
0
99
1033
0.95
0.16
1.3
1.2
13.39
26.41
iu/ml
2.88
25
282
24
266
0.90
0.16
3.0
2.5
—
—
—
0
0
24
266
0.90
0.16
5.9
2.5
—
—
—
0
0
11
130
0.84
0.16
2.7
4.8
—
—
—
0
0
8
73
1.09
0.15
1.4
1.2
—
—
—
0
0
30
274
1.09
0.14
6.6
3.2
0.10
0.12
e6/l
0.15
30
264
37
342
1.08
0.14
1.5
1.3
—
—
—
0
0
335
3281
1.03
0.14
5.7
4.7
0.00
0.00
estimate
-0.00
71
624
556
5487
1.03
0.13
3.9
3.6
4.42
4.59
mmol/l
3.50
531
5173
35
375
0.93
0.13
2.2
2.3
—
—
—
0
0
21
189
1.11
0.13
1.5
1.6
—
74.58
—
0
24
9
110
0.81
0.13
1.1
1.1
—
—
—
0
0
11
94
1.17
0.12
1.2
1.1
—
—
—
0
0
537
5405
0.98
0.12
3.7
3.3
5.61
5.63
mmol/l
0.16
496
4963
37
346
1.07
0.11
7.0
6.5
0.22
0.33
g/l
0.73
27
233
482
4853
0.98
0.10
4.7
4.4
37.27
37.89
mmol/mol
0.80
455
4558
38
401
0.94
0.10
1.1
1.2
3.31
3.12
u/ml
0.04
29
286
11
96
1.14
0.10
1.7
1.8
—
—
—
0
0
5
46
1.08
0.09
1.0
1.2
508.00
235.66
iu/ml
—
5
46
19
206
0.92
0.09
2.1
1.6
46.95
39.08
nmol/l
0.47
19
200
202
1979
1.02
0.09
2.5
2.3
—
—
—
0
0
6
58
1.03
0.08
1.0
1.2
—
—
—
0
0
332
3272
1.02
0.08
4.3
3.4
0.03
0.00
estimate
0.49
70
637
5
62
0.80
0.08
2.8
2.3
—
—
—
0
0
5
63
0.79
0.08
1.0
1.2
—
—
—
0
0
5
63
0.79
0.08
1.2
1.1
—
—
—
0
0
12
107
1.12
0.08
5.3
4.6
23.33
25.08
umol/l
0.37
12
107
6
70
0.85
0.07
2.0
1.8
—
—
—
0
0
11
122
0.90
0.07
5.0
2.6
—
—
—
0
0
424
4193
1.02
0.07
4.5
3.6
49.04
35.46
u/l
2.63
401
4000
28
264
1.06
0.07
1.9
1.7
—
—
—
0
0
548
5431
1.02
0.07
3.8
3.5
1.41
1.45
mmol/l
1.54
518
5092
8
94
0.85
0.06
1.3
1.1
—
—
—
0
0
17
157
1.08
0.06
1.2
1.2
—
—
—
0
0
12
131
0.91
0.06
1.0
1.1
—
—
—
0
0
13
119
1.09
0.05
1.6
1.2
—
—
—
0
0
16
170
0.94
0.04
1.1
1.2
3.58
14.69
u/ml
—
5
28
43
416
1.03
0.04
1.0
1.2
7.36
6.55
u/ml
0.12
31
297
18
189
0.95
0.03
1.4
1.4
3.13
4.66
ug/l
1.24
18
172
10
108
0.92
0.03
1.4
1.3
—
—
—
0
0
44
449
0.98
0.03
1.1
1.2
5.46
3.33
u/ml
0.31
31
311
552
5519
0.99
0.02
4.2
3.8
2.69
2.76
mmol/l
1.15
523
5153
42
409
1.02
0.02
1.0
1.2
1.92
1.33
u/ml
0.30
28
272
46
449
1.02
0.02
1.4
1.3
—
—
—
0
0
47
478
0.98
0.02
2.4
2.7
0.59
0.74
ug/l
0.94
24
285
334
3316
1.01
0.02
4.3
3.4
0.00
0.00
estimate
-0.00
66
606
57
577
0.98
0.01
1.4
1.4
—
—
—
0
0
24
232
1.03
0.01
1.3
1.2
—
—
—
0
0
25
242
1.03
0.01
1.1
1.2
—
—
—
0
0
12
113
1.06
0.01
1.2
1.3
—
—
—
0
0
62
626
0.99
0.01
1.6
1.9
—
—
—
0
0
19
196
0.97
0.01
1.3
1.3
—
—
—
0
0
488
4874
1.00
0.01
4.2
4.0
9.41
9.06
mm/h
0.27
452
4503
24
233
1.03
0.01
1.3
1.2
—
—
—
0
0
22
225
0.97
0.00
1.0
1.0
—
—
—
0
0
22
225
0.97
0.00
1.0
1.0
-1.07
-3.09
mmol/l
—
9
56
21
214
0.98
0.00
1.8
1.4
282.19
362.02
ug/g
1.20
16
117
12
120
1.00
0.00
1.0
1.1
—
—
—
0
0
63
629
1.00
0.00
1.5
1.4
—
—
—
0
0
50
503
0.99
0.00
2.5
1.9
12.10
14.72
iu/l
0.47
38
358
631
6294
1.00
0.00
5.2
4.2
2.03
1.89
mu/l
1.41
588
5860
22
218
1.01
0.00
1.0
1.1
—
—
—
0
0
146
1453
1.00
0.00
1.7
1.8
1.33
1.36
mmol/l
0.10
131
1278
98
977
1.00
0.00
1.4
1.4
588.33
534.88
titre
0.09
24
172
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
7.12
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.8
—
0.50
—
0
9
0
9
0.00
-0.00
0.0
1.4
—
15.98
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
—
—
0
0
9
99
0.91
-0.00
3.8
6.1
3.77
2.27
ug/l
—
9
99
0
6
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
51
0.98
-0.00
5.4
8.4
9.00
9.34
mg/l
—
5
46
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.2
—
—
—
0
0
8
89
0.90
-0.00
1.1
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.8
3.0
55.40
54.83
%
—
5
44
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
75
0.93
-0.00
1.4
1.5
—
—
—
0
0
6
60
1.00
-0.00
1.7
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
3.4
3.1
1163.20
1272.41
u/ml
—
5
49
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_VENTRICULAR_SEPTAL_DEFECT – Ventricular septal defect, a heart condition

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).