No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1466 |
4. Check minimum number of eventsNone |
1466 |
5. Include endpointsNone |
1466 |
6. Filter based on genotype QC (FinnGen only) |
1466 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_CIRCULATO_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF6v3
Similar endpoints
↥List of similar endpoints to
Atrial septal defect
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of cardiac septa
- Congenital malformations of the circulatory system
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13463 | 7684 | 5736 |
| Only index persons | 10427 | 6013 | 4414 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.19 | 0.22 | 0.16 |
| Only index persons | 0.20 | 0.22 | 0.17 |
| Median age at first event (years) | |||
| Whole population | 10.26 | 11.40 | 8.49 |
| Only index persons | 19.79 | 22.50 | 16.11 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1466 | 900 | 566 |
| Unadjusted period prevalence (%) | 0.28 | 0.31 | 0.25 |
| Median age at first event (years) | 41.27 | 39.57 | 43.98 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1344
- Matched controls
- 13352
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q21.19
ICD-10 Finland
Atrial septal defect NOS
+∞
323.0
387
*
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
+∞
323.0
354
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
323.0
746
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
47.6
323.0
624
238
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
322.5
297
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
10.0
242.5
566
907
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
8.1
227.7
632
1318
XF620
NOMESCO Finland
Examination of circulation with color method
458.9
203.5
199
5
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
26.8
200.6
284
132
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
191.9
180
*
B01AA03
ATC
warfarin; systemic
7.5
165.3
450
838
XF400
NOMESCO Finland
ECG with 12 standard connections
5.4
126.7
456
1158
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.0
124.9
772
3335
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
122.5
116
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
121.4
115
*
31
HP
Congenital heart failure surgery
+∞
112.8
107
*
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
102.1
97
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
1047.0
101.2
98
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
37.2
95.6
123
36
201
Kela drug reimbursment
Chronic cardiac insufficiency
12.3
92.9
175
160
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
7.2
92.7
243
395
XF404
NOMESCO Finland
Ambulatory ECG
6.1
90.5
271
527
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
9.3
87.7
193
237
I48
ICD-10 Finland
Atrial fibrillation and flutter
4.6
85.4
346
941
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.2
85.2
253
484
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
17.8
84.9
136
84
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
84.0
80
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
4.4
83.4
355
1011
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.3
78.6
339
971
C03CA01
ATC
furosemide; systemic
3.8
77.2
398
1335
5205
FHL
ASD blockage, secondary defect
+∞
71.3
68
*
FM2CE
NOMESCO Finland
NA
10.4
68.6
140
148
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
64.9
62
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.6
63.9
203
413
C01AA05
ATC
digoxin; systemic
7.2
63.3
163
252
PA2AE
NOMESCO Finland
Ultrasound examination of brain artery
621.0
61.1
60
*
WX872
NOMESCO Finland
Intensive care
8.1
60.5
143
194
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
20.2
58.0
88
46
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
57.8
510
2415
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
55.4
53
*
C03DA01
ATC
spironolactone; oral
4.8
55.0
198
460
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
193.2
54.2
56
*
Q25.1
ICD-10 Finland
Coarctation of aorta
545.2
53.8
53
*
C07AB07
ATC
bisoprolol; oral
2.6
52.9
566
2955
TPH07
NOMESCO Finland
Cathetrisation of artery
4.2
52.8
225
616
207
Kela drug reimbursment
Chronic arrhythmias
4.1
50.3
216
594
Q21.1
ICD-10 Finland
Atrial septal defect
+∞
49.1
47
*
FFC50
NOMESCO Finland
Closure of ostium secundum type ASD using patch
+∞
49.1
47
*
TFP20
NOMESCO Finland
Cardiodefibrillation
5.6
48.4
150
293
XF622
NOMESCO Finland
Measurement of minute volume of heart
107.3
48.0
52
5
62
HP
Catheterization and pressure measurement of the right side of the heart
49.1
47.2
57
12
Q23.11
ICD-10 Finland
Bicuspid aortic valve
+∞
47.0
45
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
8.8
46.2
102
123
XF402
NOMESCO Finland
ECG with work load test
4.0
45.9
199
550
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
7.4
45.7
113
163
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
45.4
414
1942
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
47.3
45.3
55
12
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
448.8
44.4
44
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
7.1
43.6
111
167
XA800
NOMESCO Finland
Neuropsychological investigation
4.5
43.1
165
404
WX892
NOMESCO Finland
Monitored bed care
4.1
42.9
181
486
APK
HP
ASD closure
+∞
42.8
41
*
61
HP
Catheterization and pressure measurement of the left side of the heart
17.9
42.6
67
39
AF1
HP
Surgery of congenital heart defect
+∞
41.8
40
*
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
+∞
39.7
38
*
APJ
HP
PFO closure
+∞
37.6
36
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.8
37.3
173
503
7456A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[DEFECTUS SEPTI ATRIORUM NUD]
+∞
35.5
34
*
Q21.21
ICD-10 Finland
Atrioventricular duct
+∞
35.5
34
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
5.2
35.4
116
240
I50.9
ICD-10 Finland
Heart failure, unspecified
3.7
35.0
165
485
B01AC04
ATC
clopidogrel; oral
3.3
34.5
194
655
5253
FHL
Cardiac lung machine
33.0
34.5
45
14
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
6.1
34.3
97
168
Q21.12
ICD-10 Finland
Defective sinus venosus
+∞
33.4
32
*
I34.1
ICD-10 Finland
Mitral (valve) prolapse
8.3
33.2
75
94
K78
ICPC
Atrial fibrillation/flutter
4.6
32.9
121
283
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
15.0
32.3
54
37
R4110
NOMESCO Finland
Physiotherapy
2.2
32.3
427
2336
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
12.8
32.3
58
47
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
115.3
31.7
34
*
XF600
NOMESCO Finland
Bloodpressure measurement
3.3
29.3
157
509
R4150
NOMESCO Finland
Neuropsychological rehabilitation
18.4
29.2
45
25
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
+∞
29.2
28
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
28.9
306
1496
FFC42
NOMESCO Finland
Percutaneous closure of patent foramen ovale
+∞
28.1
27
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.1
28.0
167
583
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
10.0
27.7
56
58
AA1AD
NOMESCO Finland
CT of head and brain
2.4
27.2
278
1332
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
27.1
26
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
274.3
26.7
27
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
25.5
263
1260
I50.0
ICD-10 Finland
Congestive heart failure
4.7
25.5
90
202
R4120
NOMESCO Finland
Occupational therapy
3.3
25.2
136
442
Q20.48
ICD-10 Finland
Single ventricle
+∞
25.0
24
*
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
25.0
24
*
Q26.3
ICD-10 Finland
Partial anomalous pulmonary venous connection
+∞
25.0
24
*
B01AB05
ATC
enoxaparin; parenteral
2.1
24.5
342
1878
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.8
24.3
106
291
XFE00
NOMESCO Finland
Epicardial ultrasonography
7.4
24.1
58
81
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
5.5
24.0
72
135
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
4.2
23.8
93
231
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.0
23.2
141
497
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
20.3
23.0
34
17
AP2
HP
Catheterization of the right side of the heart
36.7
23.0
29
8
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
8.3
22.9
51
63
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
84.3
22.7
25
*
WX882
NOMESCO Finland
High dependency care
3.3
22.6
121
391
AN1
HP
Coronary angiography
3.1
22.3
132
458
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
21.9
21
*
C07AA07
ATC
sotalol; systemic
5.5
21.8
66
125
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
21.8
305
1667
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
14.0
21.8
37
27
I49.5
ICD-10 Finland
Sick sinus syndrome
5.3
21.4
66
128
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.2
21.4
83
205
AP3
HP
Catheterization of the right and left side of the heart
50.5
21.1
25
5
Q21.30
ICD-10 Finland
Tetralogy of Fallot
+∞
20.8
20
*
FFC96
NOMESCO Finland
Other closure of isolated atrial septal defect
+∞
20.8
20
*
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
20.8
20
*
Q26.1
ICD-10 Finland
Persistent left superior vena cava
+∞
20.8
20
*
C01BD01
ATC
amiodarone; systemic
6.5
20.2
53
84
XX3BT
NOMESCO Finland
Other labeling with X-ray guidance
7.4
20.2
48
66
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
58.0
19.9
23
*
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
16.6
19.6
31
19
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
12.3
19.5
35
29
R06.0
ICD-10 Finland
Dyspnoea
2.0
19.2
286
1593
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
+∞
18.7
18
*
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
+∞
18.7
18
*
XF640
NOMESCO Finland
NA
5.6
18.4
54
99
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.5
18.0
147
618
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
17.7
17
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
+∞
17.7
17
*
C09AA05
ATC
ramipril; oral
2.0
17.5
236
1257
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
95.6
17.5
19
*
K90
ICPC
Stroke/cerebrovascular accident
6.2
17.4
47
78
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
4.7
17.3
59
129
C07AB02
ATC
metoprolol; systemic
2.1
17.2
208
1059
C01BC04
ATC
flecainide; systemic
4.8
17.0
57
122
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
25.8
16.9
23
9
TFP34
NOMESCO Finland
Electrophysiological investigation
4.9
16.7
55
116
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
+∞
16.7
16
*
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
16.7
16
*
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
+∞
16.7
16
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
16.6
298
1764
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
12.8
16.6
29
23
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.0
16.5
66
169
I49.3
ICD-10 Finland
Ventricular premature depolarization
3.1
16.4
93
313
G04BE03
ATC
sildenafil; oral
9.6
16.4
33
35
WX704
NOMESCO Finland
Intubation
2.8
16.1
110
418
81
HP
Angiography of the heart and coronary arteries
3.8
15.9
68
185
WX402
NOMESCO Finland
General anaesthesia
1.9
15.8
267
1543
FFC32
NOMESCO Finland
Percutaneous transluminal closure of sinus venosus type ASD
+∞
15.6
15
*
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
+∞
15.6
15
*
Z98.8
ICD-10 Finland
Other specified postsurgical states
7.0
15.6
38
55
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
5.3
15.6
47
90
B01AF02
ATC
apixaban; oral
2.8
15.5
102
377
74646
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium primum
160.6
15.5
16
*
I35.0
ICD-10 Finland
Aortic (valve) stenosis
3.8
15.0
63
169
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.5
14.9
117
483
I48.4
ICD-10 Finland
Atypical atrial flutter
56.9
14.8
17
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
56.9
14.8
17
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.3
14.6
144
667
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
+∞
14.6
14
*
Q22.5
ICD-10 Finland
Ebstein anomaly
+∞
14.6
14
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
+∞
14.6
14
*
Q21.29
ICD-10 Finland
Atrioventricular septal defect UNS
+∞
14.6
14
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
14.6
14
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
14.5
157
758
RS224
NOMESCO Finland
NA
7.3
14.4
34
47
Q87.14
ICD-10 Finland
Noonan's syndrome
150.5
14.4
15
*
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
6.2
14.4
38
62
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
14.3
122
526
FM1CD
NOMESCO Finland
Very extensive CT of heart
27.3
14.2
19
7
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
8.1
14.0
31
39
TFP35
NOMESCO Finland
Electroanatomical mapping
8.9
13.9
29
33
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
15.8
13.9
22
14
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
75.4
13.6
15
*
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
+∞
13.5
13
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
+∞
13.5
13
*
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
12.9
13.4
23
18
C10AA05
ATC
atorvastatin; oral
1.7
13.3
327
2126
I48.2
ICD-10 Finland
Chronic atrial fibrillation
6.1
13.1
35
58
GE1BE
NOMESCO Finland
Mediastinal ultrasound examinaiton through oesophagus
40.2
13.1
16
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.9
13.1
36
62
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.7
13.1
57
158
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.4
13.0
47
110
I47.1
ICD-10 Finland
Supraventricular tachycardia
3.1
13.0
71
235
K84
ICPC
Heart disease other
5.0
12.7
40
81
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
9.7
12.7
25
26
I44.2
ICD-10 Finland
Atrioventricular block, complete
5.4
12.7
37
69
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
+∞
12.5
12
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
+∞
12.5
12
*
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
+∞
12.5
12
*
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
+∞
12.5
12
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
12.5
12
*
R04.0
ICD-10 Finland
Epistaxis
2.6
12.2
88
346
I27.0
ICD-10 Finland
Primary pulmonary hypertension
21.3
12.0
17
8
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
13.4
11.9
20
15
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
14.7
11.7
19
13
Q21.2
ICD-10 Finland
Atrioventricular septal defect
+∞
11.4
11
*
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
+∞
11.4
11
*
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
+∞
11.4
11
*
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
+∞
11.4
11
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
+∞
11.4
11
*
602
Kela drug reimbursment
Children's severe malnutrition
3.9
11.4
46
120
R1260
NOMESCO Finland
Evaluation of communicative skills
4.6
11.4
39
87
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
11.4
537
4079
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
11.8
11.3
20
17
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
15.1
11.3
18
12
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
11.2
211
1257
Q90.9
ICD-10 Finland
Down syndrome, unspecified
25.1
11.1
15
6
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
11.1
354
2451
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
43.4
10.9
13
*
I44.1
ICD-10 Finland
Atrioventricular block, second degree
6.1
10.7
28
46
I47.2
ICD-10 Finland
Ventricular tachycardia
5.1
10.6
32
63
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.3
10.5
38
90
I50.1
ICD-10 Finland
Left ventricular failure
3.5
10.5
48
140
K83
ICPC
Heart valve disease NOS
8.5
10.5
22
26
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.0
10.5
41
105
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
10.4
10
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
10.4
10
*
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
10.4
10
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
10.4
10
*
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
10.4
10
*
J01CA04
ATC
amoxicillin; systemic
1.6
10.3
1105
9907
I97.0
ICD-10 Finland
Postcardiotomy syndrome
16.1
10.3
16
10
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.1
10.3
55
181
WX002
NOMESCO Finland
Sedation and analgesia
1.7
10.2
215
1322
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
13.1
10.1
17
13
7AX01
NOMESCO Finland
NA
13.1
10.1
17
13
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
10.0
162
914
R50.9
ICD-10 Finland
Fever, unspecified
1.7
10.0
218
1355
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
9.9
242
1555
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
40.1
9.9
12
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.5
9.9
79
329
AC4
HP
MVP
16.7
9.8
15
9
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
26.0
9.8
13
5
R42
ICD-10 Finland
Dizziness and giddiness
1.7
9.8
219
1375
H53.4
ICD-10 Finland
Visual field defects
5.0
9.7
30
61
ZX199
NOMESCO Finland
Other rote
7.4
9.7
22
30
51
HP
Other heart surgery
55.0
9.6
11
*
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
5.8
9.6
26
45
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.3
9.5
34
80
I63
ICD-10 Finland
Cerebral infarction
11.4
9.5
17
15
I44.0
ICD-10 Finland
Atrioventricular block, first degree
8.4
9.5
20
24
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
10.0
9.5
18
18
PD5BD
NOMESCO Finland
Extensive CT of aorta
4.8
9.4
30
63
R62.0
ICD-10 Finland
Delayed milestone
3.1
9.4
51
170
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
30.0
9.4
12
*
Q24.0
ICD-10 Finland
Dextrocardia
+∞
9.4
9
*
APX
HP
Other cardiac catheter operation
+∞
9.4
9
*
Q25.3
ICD-10 Finland
Stenosis of aorta
+∞
9.4
9
*
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
9.4
9
*
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
9.4
9
*
I51.0
ICD-10 Finland
Cardiac septal defect, acquired
+∞
9.4
9
*
5207
FHL
VSD closure
+∞
9.4
9
*
Q24.6
ICD-10 Finland
Congenital heart block
+∞
9.4
9
*
K80
ICPC
Cardiac arrhythmia NOS
2.3
9.3
84
372
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
21.7
9.3
13
6
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
6.9
9.3
22
32
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
8.7
9.2
19
22
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
3.1
9.2
48
156
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.4
9.1
73
307
Z94.1
ICD-10 Finland
Heart transplant status
11.5
9.0
16
14
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
5.9
9.0
24
41
RK260
NOMESCO Finland
NA
15.6
9.0
14
9
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
7.4
8.9
20
27
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
24.0
8.9
12
5
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
8.0
8.8
19
24
UGC02
NOMESCO Finland
Rigid bronchoscopy
8.6
8.8
18
21
B01AE07
ATC
dabigatran etexilate; oral
3.3
8.7
42
129
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.0
8.7
47
157
WW502
NOMESCO Finland
Autotransfusion
14.0
8.7
14
10
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
14.0
8.7
14
10
C02KX01
ATC
bosentan; oral
49.9
8.7
10
*
3A064
NOMESCO Finland
NA
16.3
8.5
13
8
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
3.2
8.5
43
137
1CX08
NOMESCO Finland
NA
20.0
8.4
12
6
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
4.0
8.4
32
81
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
89.9
8.4
9
*
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
89.9
8.4
9
*
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
8.3
8
*
Q21.80
ICD-10 Finland
Communication from left ventricle to right atrium
+∞
8.3
8
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
8.3
8
*
FDE10
NOMESCO Finland
Ligature of patent ductus arteriosus
+∞
8.3
8
*
7456C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[ASD CANALIS ATRIOVENTRICULARIS COMMUNIS]
+∞
8.3
8
*
AE1
HP
Pulmonary artery thrombendarterectomy
+∞
8.3
8
*
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
9.4
8.2
16
17
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.3
8.2
39
119
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.4
8.2
38
114
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
6.0
8.1
21
35
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
8.0
211
1377
AD1
HP
TVP
22.0
8.0
11
5
C09AA02
ATC
enalapril; systemic
1.7
7.8
163
996
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
25.0
7.5
10
*
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
8.8
7.5
15
17
AP1
HP
Catheterization of the left side of the heart
5.4
7.5
21
39
ZX120
NOMESCO Finland
Intravenous
1.9
7.4
114
634
1EA01
NOMESCO Finland
NA
79.9
7.4
8
*
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
79.9
7.4
8
*
I48.3
ICD-10 Finland
Typical atrial flutter
13.3
7.4
12
9
FPW96
NOMESCO Finland
Other operation for arhythmia or disturbance of impulse propagation
13.3
7.4
12
9
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
5.3
7.3
21
40
R00.2
ICD-10 Finland
Palpitations
2.0
7.3
87
441
WX870
NOMESCO Finland
Other postsurgical intensive care
8.4
7.3
15
18
90492
NOMESCO Finland
NA
+∞
7.3
7
*
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
+∞
7.3
7
*
FHB00
NOMESCO Finland
Transatrial suture of VSD
+∞
7.3
7
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
+∞
7.3
7
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
+∞
7.3
7
*
FFF20
NOMESCO Finland
Anastomosis to left atrium from partially anomalous pulmonary veins
+∞
7.3
7
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
7.3
7
*
74629
ICD-8 Finland
Congenital anomalies of heart, Tetralogy of Fallot
+∞
7.3
7
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
7.3
7
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
+∞
7.3
7
*
FM1BD
NOMESCO Finland
Extensive CT of heart
10.8
7.3
13
12
C01BD07
ATC
dronedarone; oral
9.3
7.3
14
15
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
9.3
7.3
14
15
I49.1
ICD-10 Finland
Atrial premature depolarization
3.0
7.2
39
132
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
7.2
370
2799
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
30.0
7.1
9
*
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
30.0
7.1
9
*
XQ903
NOMESCO Finland
Production of other scan or drawing
30.0
7.1
9
*
K91
ICPC
Cerebrovascular disease
6.6
7.1
17
26
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
3.9
7.0
27
70
K99
ICPC
Cardiovascular disease other
3.8
7.0
28
75
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
7.0
168
1072
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
4.3
7.0
24
56
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
4.7
7.0
22
47
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
7.0
7.0
16
23
R47.0
ICD-10 Finland
Dysphasia and aphasia
7.0
7.0
16
23
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
6.9
102
560
J96.1
ICD-10 Finland
Chronic respiratory failure
5.5
6.9
19
35
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
13.7
6.9
11
8
FKC60
NOMESCO Finland
Resection and reconstruction of leaflet of mitral valve for insufficiency
13.7
6.9
11
8
F83
ICD-10 Finland
Mixed specific developmental disorders
2.8
6.8
41
149
RS221
NOMESCO Finland
NA
3.2
6.8
33
104
AAL10
NOMESCO Finland
Intracranial endovascular thrombolysis
10.9
6.8
12
11
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
5.0
6.8
20
40
I48.1
ICD-10 Finland
Persistent atrial fibrillation
4.0
6.7
25
63
Z31.5
ICD-10 Finland
Genetic counselling
2.0
6.7
83
427
TKC20
NOMESCO Finland
Catheterisation of bladder
2.2
6.7
65
302
FFW96
NOMESCO Finland
Other operation on atria
40.0
6.7
8
*
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
4.3
6.7
23
54
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.3
6.6
31
95
C10AA01
ATC
simvastatin; oral
1.4
6.6
314
2336
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.0
6.5
77
388
B01AF01
ATC
rivaroxaban; oral
1.9
6.5
95
519
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.1
6.5
73
363
FFC40
NOMESCO Finland
Closure of Patent Foramen Ovale
69.7
6.4
7
*
FGD00
NOMESCO Finland
Repair of tricuspid valve using suture
69.7
6.4
7
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
69.7
6.4
7
*
Q90.1
ICD-10 Finland
Trisomy 21, mosaicism (mitotic nondisjunction)
69.7
6.4
7
*
A12BA01
ATC
potassium chloride; oral
2.9
6.4
37
130
342
Kela drug reimbursment
Dronedarone
7.4
6.4
14
19
73
HP
Initial pacemaker installation
8.1
6.3
13
16
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.9
6.3
36
125
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
6.3
190
1284
FM2FN
NOMESCO Finland
Intra cardiac shunt isotope imaging
+∞
6.2
6
*
FLE10
NOMESCO Finland
Myotomy or myectomy of left ventricle for outlet obstruction
+∞
6.2
6
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
6.2
6
*
Q21
ICD-10 Finland
Congenital malformations of cardiac septa
+∞
6.2
6
*
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
6.2
6
*
Q20.60
ICD-10 Finland
Left isomerism of atrial appendages
+∞
6.2
6
*
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
6.2
6
*
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
+∞
6.2
6
*
Q21.15
ICD-10 Finland
Common atrium
+∞
6.2
6
*
FDE32
NOMESCO Finland
Percutaneous transluminal closure of patent ductus arteriosus
+∞
6.2
6
*
FFF96
NOMESCO Finland
Other operation for partially anomalous pulmonary veins
+∞
6.2
6
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
6.2
6
*
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
+∞
6.2
6
*
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
+∞
6.2
6
*
FM1AD
NOMESCO Finland
CT of heart
26.6
6.2
8
*
FKC96
NOMESCO Finland
Other repair of mitral valve for insufficiency
26.6
6.2
8
*
Z95.9
ICD-10 Finland
Presence of cardiac and vascular implant and graft, unspecified
26.6
6.2
8
*
GD1LA
NOMESCO Finland
GD
4.5
6.1
20
45
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
4.5
6.1
20
45
127
Kela drug reimbursment
Transplant complication
3.0
6.1
32
107
H52.2
ICD-10 Finland
Astigmatism
2.8
6.1
36
130
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.3
6.0
28
86
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
296
504
7.05
171.42
3.7
6.3
94.9
92.9
%
0.69
288
483
881
3702
4.42
171.38
14.9
7.2
1.5
1.2
inr
10.62
189
1105
554
1674
4.68
168.06
3.6
3.5
31.0
29.9
s
3.22
544
1630
656
2326
4.26
159.17
6.0
3.2
1134.3
1069.9
ng/l
0.18
596
1929
297
651
5.43
130.38
3.6
3.4
221.0
175.0
ng/l
0.74
260
582
645
2877
3.19
100.18
6.0
5.4
80.5
91.8
%
21.33
638
2808
605
2636
3.18
97.27
2.6
2.6
—
—
—
0
0
136
182
8.08
96.32
1.1
1.1
—
—
—
0
0
136
195
7.53
90.63
1.3
1.3
4.0
4.9
u/ml
0.30
67
89
460
1789
3.26
88.41
4.1
3.5
1355.9
469.2
ng/l
2.12
368
1220
110
129
9.07
86.62
1.1
1.1
96.9
94.8
%
0.27
110
122
125
194
6.90
77.29
1.4
1.3
3.9
2.9
u/ml
0.24
49
77
855
5058
2.63
70.18
4.0
4.1
—
—
—
0
0
298
1019
3.39
69.07
44.2
18.6
2.0
1.2
inr
5.13
26
150
219
715
3.40
53.87
2.2
2.3
16.0
6.8
ug/l
3.83
196
626
377
1707
2.61
51.05
6.9
6.3
0.8
0.8
mmol/l
0.70
361
1615
536
2931
2.29
47.09
2.7
2.3
247.5
252.4
u/l
0.04
511
2785
161
478
3.63
45.59
4.6
5.9
3.0
3.3
g/l
1.64
156
461
947
6676
2.15
41.79
8.1
5.5
6.2
6.5
mmol/l
5.69
905
6219
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
109
261
4.40
41.51
11.1
7.2
0.3
0.4
u/ml
0.14
79
140
36
28
13.06
37.23
4.0
9.0
—
—
—
0
0
41
44
9.49
34.28
1.0
1.0
100.0
94.7
%
0.43
36
38
553
3441
1.96
31.67
4.7
3.3
59.6
45.0
ng/l
0.36
379
2123
228
1029
2.42
29.70
15.5
9.0
5.3
5.2
kpa
1.41
223
990
228
1029
2.42
29.70
15.5
9.0
13.2
12.7
kpa
0.47
223
994
227
1031
2.40
29.13
15.6
9.0
1.2
1.0
mmol/l
0.27
198
823
45
67
6.85
28.71
1.2
1.1
—
—
—
0
0
138
494
2.96
28.47
21.6
12.4
—
—
—
0
0
44
70
6.40
26.38
1.0
1.1
1.1
1.1
ratio
—
5
31
1352
11773
2.81
26.13
23.2
14.3
139.5
139.6
mmol/l
0.76
1344
11465
1353
11794
2.81
25.94
23.2
14.4
4.0
4.0
mmol/l
1.62
1344
11456
728
5199
1.78
25.13
12.5
8.4
1.2
1.2
mmol/l
7.97
686
4793
407
2456
1.89
24.34
3.2
2.5
1.2
1.3
mg/l
0.08
295
1837
143
590
2.56
22.35
20.3
10.8
0.7
0.7
%
0.20
143
585
143
594
2.54
22.04
20.0
10.7
1.3
1.4
%
0.77
143
588
264
1448
1.99
20.59
16.1
12.8
25.4
24.6
mmol/l
5.64
264
1442
177
835
2.26
20.48
14.2
9.7
121.1
122.5
g/l
0.36
170
813
755
5646
1.68
20.46
10.8
8.6
1.2
1.2
mmol/l
5.67
673
4927
733
5452
1.67
20.18
8.7
6.8
16.9
14.1
umol/l
2.07
690
5140
625
4466
1.68
20.02
5.8
5.7
36.3
36.3
g/l
0.08
585
4194
307
1796
1.88
19.69
8.4
8.2
1.2
1.2
mmol/l
1.06
298
1689
266
1487
1.95
19.56
3.3
2.7
21.2
22.9
%
1.47
247
1329
1347
11998
2.42
19.54
18.7
12.6
23.8
22.2
mg/l
1.11
1120
9074
299
1747
1.88
19.20
3.2
2.6
12.8
13.6
umol/l
1.30
282
1637
279
1600
1.90
18.96
3.2
2.6
2.4
2.4
g/l
0.16
263
1501
285
1671
1.86
18.00
1.9
2.0
—
—
—
0
0
198
1047
2.02
16.94
17.3
9.2
1.3
1.4
mmol/l
0.45
193
979
206
1109
1.98
16.74
4.5
5.0
267.5
270.6
u/l
0.06
198
1058
242
1384
1.88
16.41
9.9
7.8
1.8
1.0
mmol/l
5.96
199
989
49
133
3.75
15.75
3.0
3.0
0.8
0.9
nmol/l
0.25
37
105
264
1578
1.81
15.47
6.5
7.8
1.5
1.4
mmol/l
0.03
222
1259
55
164
3.42
15.38
8.5
6.7
11.8
11.2
mg/l
0.28
47
152
95
394
2.49
14.65
2.5
2.1
1.2
1.4
g/l
1.92
79
349
211
1197
1.88
14.58
7.0
8.7
24.2
23.7
mmol/l
1.40
205
1138
31
64
4.89
14.15
2.1
1.3
27184.8
32817.5
e6/l
0.14
21
36
794
6351
1.53
13.89
7.2
7.6
28.6
31.4
%
10.49
755
6017
414
2914
1.57
12.75
2.8
2.5
3.2
2.9
mg/l
1.55
370
2525
207
1218
1.80
12.63
1.8
2.0
—
—
—
0
0
31
71
4.41
12.52
2.1
1.3
1520.3
1869.8
e6/l
0.23
23
50
205
1216
1.78
12.16
1.8
1.9
—
—
—
0
0
511
3810
1.51
11.94
4.3
3.8
33.3
32.8
u/l
0.05
484
3635
872
7253
1.48
11.67
9.2
10.1
3.9
3.9
e9/l
0.06
769
6232
224
1388
1.71
11.36
4.9
4.7
8.6
7.5
umol/l
0.43
204
1171
994
8512
1.50
11.30
4.7
4.1
10.3
10.4
mm/h
0.09
950
7939
975
8340
1.48
10.96
8.4
6.9
89.1
90.0
u/l
0.16
930
7831
133
726
1.90
10.26
2.1
3.1
65.0
66.4
g/l
0.97
120
671
214
1351
1.67
10.07
3.4
4.6
1.9
1.6
%
1.95
199
1244
77
353
2.23
9.53
1.7
2.0
—
—
—
0
0
76
348
2.23
9.43
1.7
2.1
—
—
—
0
0
63
268
2.39
9.27
1.9
2.1
—
—
—
0
0
66
288
2.34
9.17
1.7
1.5
—
—
—
0
0
677
5519
1.41
9.16
3.7
3.0
108.2
96.5
ug/l
0.74
637
5175
136
780
1.81
8.98
2.6
2.6
70.0
70.9
ml/min/173m2
0.08
48
300
15
26
5.78
8.26
1.5
1.6
—
—
—
0
0
21
53
3.98
7.54
1.3
1.3
72.7
86.6
%
0.59
14
22
21
54
3.90
7.36
1.2
1.0
79.9
89.3
%
0.53
14
23
18
41
4.40
7.36
1.2
1.0
77.3
87.0
%
—
6
10
96
530
1.85
7.19
9.9
8.0
24.8
24.5
mmol/l
0.23
89
499
224
1560
1.50
6.82
1.7
1.7
1146.7
1196.7
nmol/l
0.35
170
1183
1087
9814
1.39
6.80
16.5
10.8
87.4
87.5
ml/min/173m2
0.05
944
7774
169
1115
1.57
6.58
8.2
6.1
—
—
—
0
0
17
41
4.15
6.49
2.2
2.0
—
—
—
0
0
39
160
2.46
6.29
1.4
1.6
—
—
—
0
0
48
217
2.24
6.23
1.4
1.6
—
—
—
0
0
45
198
2.30
6.23
1.6
1.6
—
—
—
0
0
420
3326
1.36
6.18
3.9
3.5
0.5
0.4
e6/l
0.33
332
2472
1165
10694
1.40
6.17
22.6
15.9
13.6
13.5
%
2.22
1153
10485
28
98
2.87
6.14
1.8
1.8
—
—
—
0
0
28
98
2.87
6.14
1.8
1.8
—
—
—
0
0
28
98
2.87
6.14
1.8
1.8
—
—
—
0
0
51
238
2.17
6.14
1.4
2.0
—
—
—
0
0
62
315
2.00
5.98
1.5
2.4
—
—
—
0
0
16
40
4.00
5.84
2.2
2.0
—
—
—
0
0
16
40
4.00
5.84
2.2
2.0
—
—
—
0
0
115
719
1.64
5.61
3.2
3.1
4.5
4.8
pmol/l
1.65
103
648
23
76
3.04
5.59
6.9
5.3
115.0
71.5
mg/l
0.62
18
67
59
303
1.97
5.54
2.5
2.7
—
—
—
0
0
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
16
42
3.81
5.48
1.4
1.0
52.8
70.0
%
—
5
10
849
7514
1.29
5.32
4.8
4.2
234.2
2668.5
e6/l
1.64
15
95
68
374
1.84
5.22
1.5
1.8
—
—
—
0
0
18
54
3.34
5.11
2.1
1.9
—
—
—
0
0
18
54
3.34
5.11
2.1
1.9
—
—
—
0
0
18
54
3.34
5.11
2.1
1.9
—
—
—
0
0
18
54
3.34
5.11
2.1
1.9
—
—
—
0
0
1413
13591
1.90
5.10
27.7
18.5
4.5
4.5
e12/l
3.76
1387
13123
34
145
2.36
5.10
1.3
1.6
—
—
—
0
0
139
932
1.53
5.06
3.3
3.0
—
—
—
0
0
1412
13582
1.88
5.04
27.7
18.5
246.2
259.8
e9/l
12.35
1389
13154
1413
13596
1.89
5.02
27.7
18.5
6.8
6.8
e9/l
0.07
1390
13124
37
165
2.26
5.02
1.3
1.6
—
—
—
0
0
1413
13597
1.88
5.00
28.6
18.6
133.0
135.0
g/l
5.21
1407
13423
44
211
2.10
5.00
1.5
2.0
—
—
—
0
0
84
499
1.71
4.99
1.6
1.8
—
—
—
0
0
272
2074
1.37
4.98
2.7
3.0
0.9
1.0
e6/l
0.15
156
1159
312
2435
1.35
4.92
3.5
2.8
5.1
6.4
e6/l
0.99
278
2123
1246
11679
1.40
4.91
22.4
14.3
39.5
39.8
%
0.96
999
9386
1163
10786
1.34
4.89
5.2
4.5
2.0
2.1
mu/l
0.40
1092
10031
16
46
3.48
4.84
1.6
1.1
10.3
12.0
u/l
0.24
16
41
63
347
1.84
4.84
2.5
3.7
30.2
35.5
umol/l
1.66
58
303
401
3252
1.31
4.83
2.9
2.6
62.5
56.2
u/l
1.25
372
3024
34
153
2.24
4.54
2.0
1.9
—
—
—
0
0
43
214
2.03
4.46
3.0
2.7
17.3
16.7
%
0.41
26
125
426
3524
1.28
4.34
3.0
3.2
2.4
2.4
mmol/l
0.13
373
3137
279
2183
1.33
4.28
1.6
1.5
20.8
21.0
nmol/l
0.07
249
1881
47
248
1.91
4.16
1.5
2.1
37.5
38.2
g/l
0.23
40
221
844
7585
1.25
4.14
4.0
3.5
48.0
44.2
u/l
0.80
806
7186
49
263
1.88
4.12
1.9
2.2
0.5
1.0
g/l
0.79
42
241
1039
9566
1.27
4.11
5.1
5.0
37.9
39.0
mmol/mol
3.93
977
8977
57
324
1.78
4.00
1.5
1.4
—
—
—
0
0
64
377
1.72
3.98
2.2
2.0
—
—
—
0
0
40
206
1.95
3.82
1.8
1.4
—
—
—
0
0
462
3916
1.25
3.75
2.1
1.8
99.3
96.3
pmol/l
0.68
260
2023
26
114
2.29
3.73
2.6
2.2
32.0
32.7
pg
0.27
26
114
50
280
1.80
3.71
2.0
2.1
11.1
10.4
g/l
0.36
42
248
37
188
1.98
3.68
2.1
1.8
—
—
—
0
0
42
224
1.89
3.63
1.5
2.2
0.0
0.0
g/l
0.00
37
211
147
1066
1.41
3.63
2.4
2.4
38.4
82.6
u/l
0.47
129
888
142
1025
1.42
3.60
1.2
1.4
151.5
310.0
u/ml
2.31
135
961
72
451
1.62
3.58
1.3
1.6
1.1
1.2
g/l
0.85
66
431
44
240
1.85
3.56
1.5
2.1
0.0
0.0
g/l
0.50
39
226
42
226
1.87
3.54
1.5
2.2
0.0
0.0
g/l
0.00
37
212
50
286
1.76
3.48
2.0
2.1
3.1
3.1
g/l
0.03
42
234
310
2529
1.28
3.45
3.7
3.0
2712.1
5490.7
umol/l
0.56
271
2234
107
739
1.47
3.44
1.9
1.7
—
—
—
0
0
22
97
2.27
3.15
1.8
1.7
65.5
56.6
%
0.69
16
69
43
244
1.77
3.10
1.2
1.3
36.8
6.7
u/ml
—
5
17
90
619
1.47
2.99
1.8
1.7
—
—
—
0
0
249
2014
1.27
2.96
3.0
3.2
3.2
2.5
e6/l
0.46
135
1109
50
302
1.67
2.91
2.0
2.0
3.8
3.8
g/l
0.09
41
230
50
302
1.67
2.91
2.0
2.0
—
—
—
0
0
50
302
1.67
2.91
2.0
2.0
7.0
7.4
g/l
0.88
42
240
11
35
3.14
2.90
1.5
4.1
—
—
—
0
0
1292
12369
1.31
2.89
12.3
9.8
26.2
26.6
u/l
0.27
1263
11972
52
318
1.65
2.89
1.5
1.4
—
—
—
0
0
52
318
1.65
2.89
1.5
1.4
—
—
—
0
0
989
9205
1.21
2.84
4.5
3.9
14.8
14.6
pmol/l
2.78
918
8458
12
41
2.92
2.82
1.8
1.5
—
—
—
0
0
67
439
1.54
2.81
1.4
1.6
0.2
0.2
g/l
0.64
62
421
124
916
1.38
2.79
5.5
5.4
77.8
68.0
ng/l
1.30
109
846
40
233
1.72
2.68
1.7
1.4
—
—
—
0
0
16
67
2.39
2.59
1.1
1.1
226.9
222.4
iu/ml
0.02
16
67
50
313
1.61
2.57
1.2
1.3
3.5
8.0
u/ml
0.64
14
41
17
74
2.30
2.54
1.2
1.2
—
—
—
0
0
49
307
1.61
2.51
1.3
1.3
2.1
5.0
u/ml
—
9
28
29
157
1.85
2.48
1.0
1.1
—
—
—
0
0
212
1719
1.26
2.47
2.4
2.7
2.4
2.4
mmol/l
1.57
179
1492
28
150
1.87
2.47
1.0
1.1
—
—
—
0
0
54
348
1.56
2.47
2.6
2.0
0.8
2.2
ug/l
0.95
49
312
57
375
1.53
2.39
1.1
1.2
—
—
—
0
0
48
304
1.59
2.37
2.1
1.8
5.2
5.3
iu/l
0.01
17
105
53
344
1.55
2.36
1.9
1.8
—
—
—
0
0
50
321
1.57
2.34
11.4
8.7
1013.0
322.0
iu/ml
—
10
48
17
77
2.21
2.34
1.3
1.8
—
—
—
0
0
30
168
1.79
2.32
3.5
3.9
1.1
1.4
%
0.19
25
135
142
1106
1.30
2.28
3.4
3.4
10.1
9.7
g/l
0.43
134
1040
20
99
2.02
2.22
1.4
1.9
—
—
—
0
0
57
382
1.50
2.21
1.1
1.2
—
—
—
0
0
1084
10266
1.19
2.18
4.4
3.9
5.7
5.8
mmol/l
2.08
1008
9440
35
557
0.61
2.17
1.1
1.2
7.3
2.7
u/ml
0.43
19
342
22
115
1.91
2.12
1.1
1.1
—
—
—
0
0
626
5692
1.16
2.11
3.6
3.4
0.0
0.0
estimate
0.00
96
1001
48
314
1.54
2.10
5.9
4.0
1.2
1.4
mmol/l
1.50
48
306
26
146
1.78
2.03
1.0
1.0
—
—
—
0
0
6
15
3.98
2.02
2.2
2.3
—
—
—
0
0
41
261
1.58
2.02
3.1
2.5
137.6
131.3
g/l
0.93
32
202
1108
10540
1.18
2.00
4.6
4.0
4.3
4.7
mmol/l
25.26
1050
9895
19
97
1.96
1.97
1.9
1.6
—
—
—
0
0
15
294
0.50
1.96
1.0
1.1
0.0
0.4
u/ml
—
6
128
15
71
2.11
1.89
1.5
1.2
—
42.7
—
0
6
226
1903
1.21
1.88
1.3
1.3
17.5
28.2
iu/ml
3.00
64
548
36
548
0.64
1.88
1.5
1.8
—
—
—
0
0
44
291
1.52
1.86
4.4
4.1
9.8
9.9
umol/l
0.00
31
233
14
65
2.15
1.85
4.4
4.9
—
—
—
0
0
24
401
0.59
1.85
1.3
1.4
—
—
—
0
0
83
624
1.34
1.76
1.5
1.4
—
—
—
0
0
6
18
3.32
1.73
1.0
1.1
—
—
—
0
0
7
24
2.91
1.71
1.7
1.4
—
—
—
0
0
323
2834
1.17
1.69
1.6
1.7
1.3
1.4
mmol/l
0.66
278
2457
62
449
1.39
1.67
5.1
4.4
55.5
51.4
%
0.64
62
440
1057
10069
1.15
1.66
4.2
3.6
1.2
1.3
mmol/l
4.99
991
9384
19
105
1.81
1.60
1.6
2.4
41.2
25.3
mg/l
—
5
29
104
831
1.26
1.45
2.8
4.2
3.7
17.1
ug/l
1.50
84
670
1111
10658
1.15
1.44
5.0
4.3
2.6
2.8
mmol/l
17.41
1041
9946
19
109
1.74
1.44
1.5
1.2
357.9
116.4
u/l
0.36
11
80
139
1152
1.22
1.40
4.3
4.0
34.0
31.7
%
1.54
109
797
48
345
1.39
1.39
1.4
2.8
3.6
3.6
mmol/l
0.12
43
329
35
237
1.48
1.38
4.9
4.3
56.0
55.9
%
0.02
35
237
1092
10474
1.14
1.38
4.6
3.9
1.4
1.5
mmol/l
3.95
1030
9786
620
5759
1.12
1.35
3.7
3.5
0.0
0.0
estimate
0.80
100
997
105
848
1.25
1.35
2.1
2.3
23.7
19.5
au/ml
—
7
50
0
37
0.00
1.34
0.0
1.1
—
—
—
0
0
18
104
1.73
1.34
1.2
1.1
—
—
—
0
0
16
90
1.77
1.30
2.6
3.7
—
—
—
0
0
614
5713
1.12
1.28
5.0
4.8
0.0
0.0
estimate
0.50
103
1034
17
98
1.73
1.28
1.2
1.2
—
—
—
0
0
8
36
2.21
1.23
2.3
1.9
0.3
1.3
mg/l
—
8
27
8
36
2.21
1.23
2.3
1.9
1.6
6.3
mg/l
—
8
29
8
36
2.21
1.23
2.3
1.9
1.4
1.1
mg/l
—
8
30
8
36
2.21
1.23
2.3
1.9
1.8
2.0
mg/l
—
8
30
8
36
2.21
1.23
2.3
1.9
1.5
1.6
mg/l
—
8
28
8
36
2.21
1.23
2.3
1.9
0.3
0.8
mg/l
—
8
30
8
36
2.21
1.23
2.3
1.9
1.9
1.5
mg/l
—
8
30
8
36
2.21
1.23
2.3
1.9
1.5
3.4
mg/l
—
8
29
0
34
0.00
1.16
0.0
1.3
—
—
—
0
0
10
50
1.99
1.14
1.3
1.8
—
—
—
0
0
19
118
1.61
1.12
1.2
1.3
—
—
—
0
0
19
118
1.61
1.12
1.2
1.3
—
—
—
0
0
32
224
1.43
1.11
1.9
1.8
12377.1
14104.1
e6/l
0.12
24
170
46
343
1.34
1.11
1.5
3.1
2.1
7.5
e6/l
1.68
36
260
46
343
1.34
1.11
1.5
3.1
178.9
542.3
e6/l
0.77
37
267
11
58
1.89
1.10
1.3
1.7
—
—
—
0
0
24
159
1.51
1.09
1.5
1.2
—
—
—
0
0
19
119
1.59
1.09
1.2
1.3
—
—
—
0
0
19
119
1.59
1.09
1.2
1.3
—
—
—
0
0
19
119
1.59
1.09
1.2
1.3
—
—
—
0
0
23
151
1.52
1.09
1.5
1.5
—
—
—
0
0
33
234
1.41
1.08
2.0
3.6
32.0
44.3
mg/l
0.42
25
185
33
234
1.41
1.08
2.0
3.6
51.1
73.9
mg/l
0.36
25
184
206
1813
1.15
1.06
1.3
1.2
11.7
9.0
u/ml
0.17
70
665
47
355
1.33
1.05
1.5
1.4
266.2
318.9
ug/g
0.87
25
204
10
52
1.92
1.04
1.3
1.8
—
—
—
0
0
95
786
1.21
1.02
1.3
1.3
—
—
—
0
0
85
1016
0.82
1.00
1.1
1.1
—
—
—
0
0
7
134
0.52
0.98
1.3
2.0
—
—
—
0
0
10
54
1.84
0.95
1.1
1.1
—
—
—
0
0
23
326
0.70
0.94
4.7
2.2
0.8
0.7
nmol/l
0.33
18
279
8
144
0.55
0.93
1.5
2.0
0.1
0.1
nmol/l
—
8
102
32
233
1.37
0.92
4.3
3.9
4.2
4.1
e9/l
0.06
32
233
9
52
1.72
0.91
1.1
1.2
—
—
—
0
0
9
52
1.72
0.91
1.1
1.2
—
—
—
0
0
81
670
1.21
0.90
1.9
2.3
7442.8
4415.2
u/l
0.31
27
247
21
142
1.48
0.90
1.2
1.3
—
—
—
0
0
6
29
2.06
0.89
2.7
7.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
16
102
1.56
0.88
1.1
1.2
—
—
—
0
0
13
79
1.64
0.86
1.5
1.2
—
—
—
0
0
319
2925
1.11
0.86
4.1
3.7
0.0
0.0
estimate
1.28
99
1006
187
2066
0.88
0.85
2.1
2.3
—
—
—
0
0
389
3605
1.10
0.84
1.4
1.5
0.9
2.7
u/ml
5.31
93
820
6
31
1.93
0.84
2.3
2.1
—
—
—
0
0
10
57
1.75
0.82
2.8
4.2
—
—
—
0
0
8
46
1.73
0.82
1.6
1.2
—
—
—
0
0
91
770
1.19
0.81
1.2
1.3
15.9
42.7
au/ml
—
7
31
42
527
0.79
0.80
1.6
1.4
—
—
—
0
0
26
188
1.38
0.80
1.2
1.1
—
—
—
0
0
50
400
1.25
0.78
1.5
1.4
—
—
—
0
0
5
23
2.16
0.76
1.6
1.8
—
—
—
0
0
9
53
1.69
0.75
1.1
1.1
—
—
—
0
0
61
502
1.22
0.74
1.5
1.3
—
—
—
0
0
9
54
1.66
0.74
1.1
1.2
—
—
—
0
0
9
54
1.66
0.74
1.9
1.4
—
—
—
0
0
9
54
1.66
0.74
1.9
1.4
—
—
—
0
0
21
287
0.72
0.74
1.4
1.8
—
—
—
0
0
5
25
1.99
0.72
1.2
1.8
—
—
—
0
0
171
1875
0.89
0.70
2.0
2.1
—
—
—
0
0
5
26
1.91
0.70
3.0
2.7
—
—
—
0
0
25
185
1.35
0.69
1.5
1.4
17.2
19.9
u/l
0.20
18
157
449
4229
1.08
0.67
3.7
3.5
—
—
—
0
0
14
200
0.69
0.65
1.1
1.3
—
—
—
0
0
7
44
1.58
0.64
2.1
1.5
—
—
—
0
0
7
44
1.58
0.64
2.1
1.5
—
—
—
0
0
55
457
1.20
0.63
1.7
2.0
37.3
39.9
u/l
0.49
48
415
293
2722
1.09
0.61
4.1
4.0
11.3
7.7
mg/mmol
0.39
188
1768
143
1282
1.12
0.61
3.1
2.4
333.9
354.2
nmol/l
0.49
133
1206
11
72
1.52
0.57
1.2
1.8
—
—
—
0
0
5
86
0.58
0.56
1.0
1.1
—
1.3
nmol/l
—
0
19
273
2541
1.08
0.56
3.7
3.6
1.0
1.0
kg/l
0.11
36
381
41
490
0.83
0.56
1.6
1.7
3.3
3.4
mg/l
0.03
25
336
6
37
1.61
0.55
5.8
2.4
—
—
—
0
0
6
37
1.61
0.55
1.0
1.1
—
—
—
0
0
510
4857
1.07
0.55
3.0
2.6
76.0
74.4
nmol/l
0.62
461
4446
9
59
1.52
0.54
4.3
3.5
80.2
137.0
ug/l
—
9
59
9
59
1.52
0.54
5.2
8.5
—
—
—
0
0
6
38
1.57
0.54
2.2
2.3
—
—
—
0
0
6
38
1.57
0.54
1.0
1.1
—
—
—
0
0
24
187
1.28
0.50
2.5
3.8
—
—
—
0
0
351
3312
1.07
0.50
3.5
3.6
7.5
7.8
mmol/l
0.54
303
2872
26
322
0.80
0.50
1.5
1.5
—
—
—
0
0
12
83
1.44
0.50
1.1
1.5
—
—
—
0
0
17
222
0.76
0.49
1.5
1.6
—
—
—
0
0
10
142
0.70
0.47
2.6
1.9
—
—
—
0
0
17
128
1.32
0.46
1.1
1.1
—
—
—
0
0
5
84
0.59
0.45
1.4
1.4
—
—
—
0
0
73
815
0.88
0.45
1.5
1.5
—
—
—
0
0
247
2316
1.07
0.43
4.0
4.2
1.6
2.1
ug/l
1.70
215
2108
5
31
1.60
0.43
1.0
1.1
41.1
33.8
u/ml
—
5
31
8
58
1.37
0.41
1.3
1.1
1281.2
1556.7
miu/ml
—
8
58
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
61
536
1.14
0.40
2.6
2.8
0.1
0.2
e6/l
1.70
61
518
167
1548
1.08
0.40
1.6
1.7
1.4
1.4
%
0.03
151
1389
18
140
1.28
0.40
1.1
1.7
—
—
—
0
0
7
104
0.67
0.39
1.0
2.2
—
—
—
0
0
5
35
1.42
0.39
2.6
1.6
—
—
—
0
0
45
389
1.15
0.38
2.3
1.9
—
15.8
—
0
7
13
97
1.33
0.38
1.2
1.2
—
—
—
0
0
10
71
1.40
0.38
1.4
1.9
—
—
—
0
0
5
36
1.38
0.38
1.0
1.8
—
—
—
0
0
24
196
1.22
0.37
2.4
3.6
15.2
9.6
%
1.04
17
159
22
266
0.82
0.37
1.2
1.1
1.8
4.5
u/ml
—
10
104
15
190
0.78
0.37
1.1
1.1
—
—
—
0
0
9
71
1.26
0.36
3.1
3.4
1256.4
969.3
u/ml
—
9
71
10
72
1.38
0.35
1.0
1.1
—
—
—
0
0
43
373
1.15
0.35
2.3
1.9
99.3
101.6
u/ml
—
9
40
6
42
1.42
0.35
1.2
1.3
—
—
—
0
0
93
1005
0.91
0.35
1.9
1.9
—
—
—
0
0
19
231
0.81
0.34
1.0
1.0
19.4
19.4
mmol/l
0.03
19
223
35
401
0.86
0.34
1.5
1.5
—
—
—
0
0
31
263
1.17
0.34
1.2
1.2
—
—
—
0
0
96
878
1.09
0.33
2.3
2.2
11.1
11.9
nmol/l
0.39
81
747
40
452
0.88
0.32
1.5
1.5
—
—
—
0
0
67
605
1.10
0.31
1.8
1.9
9.0
7.4
u/l
0.41
42
410
115
1223
0.93
0.31
2.1
2.0
—
—
—
0
0
7
53
1.31
0.30
1.3
1.3
—
71.3
—
0
8
351
3367
1.05
0.30
1.9
1.8
—
—
—
0
0
19
227
0.83
0.30
1.0
1.0
-2.1
-2.2
mmol/l
—
8
48
102
942
1.08
0.30
1.2
1.2
139.2
148.0
iu/ml
0.07
37
353
47
417
1.12
0.29
1.4
1.3
—
—
—
0
0
965
9453
1.04
0.29
3.5
3.5
—
—
—
0
0
18
148
1.21
0.27
2.6
4.2
11798.3
1961.7
u/ml
0.38
18
141
10
76
1.31
0.27
1.0
1.0
—
—
—
0
0
182
1892
0.95
0.26
2.0
2.8
108.8
110.1
ug/g
0.02
136
1530
23
196
1.17
0.25
3.3
3.6
0.3
0.2
e9/l
0.78
18
155
9
73
1.23
0.25
1.2
1.5
—
—
—
0
0
34
378
0.89
0.24
1.3
1.5
—
—
—
0
0
5
37
1.34
0.23
1.0
1.2
—
—
—
0
0
33
367
0.89
0.23
1.7
1.7
—
—
—
0
0
12
96
1.24
0.23
1.2
1.2
—
—
—
0
0
5
38
1.31
0.23
1.2
1.4
9.5
9.2
ug/l
—
5
38
23
198
1.16
0.23
3.2
3.6
364.7
539.9
e6/l
1.58
18
155
28
245
1.14
0.23
1.5
1.3
86.9
126.9
pmol/l
0.40
28
239
5
39
1.27
0.22
3.2
6.8
—
—
—
0
0
5
39
1.27
0.22
3.6
6.9
—
—
—
0
0
37
407
0.90
0.22
1.5
1.4
—
—
—
0
0
60
551
1.08
0.22
1.6
1.8
—
—
—
0
0
108
1132
0.94
0.21
1.7
1.6
—
—
—
0
0
37
406
0.90
0.21
1.4
1.4
—
—
—
0
0
37
406
0.90
0.21
1.4
1.4
—
—
—
0
0
11
88
1.24
0.21
1.3
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
8.9
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
8
100
0.79
0.21
1.0
1.1
350.4
292.0
mg/l
—
8
91
46
418
1.10
0.21
1.2
1.1
3.2
6.2
u/ml
—
6
72
37
405
0.90
0.21
1.4
1.4
—
—
—
0
0
0
13
0.00
0.20
0.0
1.3
—
—
—
0
0
6
47
1.27
0.20
1.2
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
16
185
0.86
0.19
1.2
1.2
—
—
—
0
0
19
164
1.15
0.19
1.3
1.8
—
1474.3
—
0
7
10
81
1.23
0.17
1.1
1.5
—
—
—
0
0
26
232
1.11
0.17
1.2
1.3
—
—
—
0
0
56
521
1.07
0.16
1.2
1.2
—
—
—
0
0
34
310
1.09
0.15
1.0
1.1
—
—
—
0
0
12
102
1.17
0.14
1.2
3.9
—
—
—
0
0
12
102
1.17
0.14
1.3
3.9
—
—
—
0
0
18
200
0.89
0.14
4.6
3.1
1.8
1.5
mmol/l
0.63
18
195
22
199
1.10
0.12
1.0
1.1
14.9
8.5
iu/ml
—
5
28
10
85
1.17
0.11
1.0
1.2
—
—
—
0
0
10
85
1.17
0.11
1.6
1.6
0.9
1.0
g/l
—
10
85
20
181
1.10
0.11
3.6
2.9
531.5
719.1
e6/l
—
6
36
201
1954
1.02
0.10
1.5
1.6
468.5
38253448.4
pmol/l
2.41
167
1660
15
134
1.11
0.09
6.7
4.2
23.5
26.2
umol/l
0.88
15
134
5
46
1.08
0.09
1.4
2.4
14.8
18.6
umol/l
—
5
46
12
106
1.13
0.09
1.1
1.2
—
—
—
0
0
34
319
1.06
0.09
5.3
4.0
24.9
21.8
nmol/l
0.48
34
311
6
55
1.08
0.08
1.3
1.4
—
86.6
%
—
0
7
26
242
1.07
0.08
1.6
1.4
—
—
—
0
0
10
88
1.13
0.07
3.8
2.6
73.7
54.6
umol/l
—
10
75
49
468
1.04
0.07
1.5
1.3
291.9
244.8
miu/ml
0.35
24
221
8
78
1.02
0.07
8.0
10.0
0.7
0.6
mmol/l
—
8
72
9
87
1.03
0.07
1.1
2.2
—
—
—
0
0
190
1916
0.98
0.07
1.4
1.5
—
—
—
0
0
10
90
1.10
0.04
1.2
1.3
—
—
—
0
0
10
90
1.10
0.04
1.2
1.3
78.2
79.5
%
—
10
90
13
138
0.93
0.03
2.1
1.5
—
—
—
0
0
187
1840
1.01
0.03
3.8
3.8
23.8
21.2
%
1.00
70
772
46
446
1.02
0.03
1.8
1.7
271.3
207.0
u/ml
0.75
34
229
47
456
1.02
0.03
1.8
1.7
—
—
—
0
0
13
137
0.94
0.02
2.1
1.5
—
—
—
0
0
13
137
0.94
0.02
2.1
1.5
—
—
—
0
0
15
142
1.05
0.01
1.3
1.3
0.7
0.6
nmol/l
0.71
15
134
13
136
0.95
0.01
2.1
1.5
—
—
—
0
0
139
1372
1.01
0.01
2.6
2.7
0.8
0.7
ug/l
0.23
85
812
13
135
0.96
0.00
2.1
1.5
—
—
—
0
0
13
135
0.96
0.00
2.1
1.5
—
—
—
0
0
15
151
0.99
0.00
1.2
1.3
7.5
7.4
mmol/l
—
10
99
75
745
1.00
0.00
1.8
1.7
23.0
21.0
iu/l
0.20
58
555
17
171
0.99
0.00
2.4
1.6
—
—
—
0
0
10
101
0.98
0.00
1.1
1.0
—
—
—
0
0
21
209
1.00
0.00
3.1
2.4
137.4
110.2
ug/min
0.10
11
137
7
72
0.97
0.00
1.1
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
—
—
0
0
8
86
0.92
0.00
2.3
2.3
—
—
—
0
0
5
49
1.01
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
30.8
—
0
5
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
829.4
—
0
5
0
6
0.00
0.00
0.0
9.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
7.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
12.3
—
0
8
0
5
0.00
0.00
0.0
7.8
—
—
—
0
0
0
7
0.00
0.00
0.0
3.1
—
—
—
0
0
0
8
0.00
0.00
0.0
4.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_ASD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_ASD | 1.807 [1.57, 2.09] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.845 |
During the follow-up period (1.1.1998 — 31.12.2019), 451 out of 5990 females with Q17_ASD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_ASD | 1.752 [1.5, 2.04] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 363 out of 4494 males with Q17_ASD died.
Mortality risk
Mortality risk for people of age
years, who have Q17_ASD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.2% | 0.337% |
| 5 | 1.099% | 2.003% |
| 10 | 2.988% | 5.23% |
| 15 | 5.839% | 9.857% |
| 20 | 10.621% | 15.809% |
Relationships between endpoints
↥Index endpoint: Q17_ASD – Atrial septal defect
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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