Atrial septal defect

Q17_ASD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q21.1
  • Hospital discharge: ICD-9 7455A|7456A
  • Hospital discharge: excluded ICD-10 Q20|Q2111|Q2[2-5]|Q26[0-1]|Q26[5-9]
  • Cause of death: ICD-10 Q21.1
  • Cause of death: ICD-9 7455A|7456A
  • Cause of death: excluded ICD-10 Q20|Q2111|Q2[2-5]|Q26[0-1]|Q26[5-9]
  • Operations: NOMESCO codes ^FFC00|^FFC02|^FFC22|^FFC50|^FFC96

3 out of 7 registries used, show all original rules.

1502

4. Check minimum number of events

None

1502

5. Include endpoints

None

1502

6. Filter based on genotype QC (FinnGen only)

1443

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_CIRCULATO_SYSTEM

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6v3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13463 7684 5736
Only index persons 10427 6013 4414
Unadjusted period prevalence (%)
Whole population 0.19 0.22 0.16
Only index persons 0.20 0.22 0.17
Median age at first event (years)
Whole population 10.26 11.40 8.49
Only index persons 19.79 22.50 16.11

-FinnGen-

Key figures

All Female Male
Number of individuals 1443 887 556
Unadjusted period prevalence (%) 0.29 0.31 0.25
Median age at first event (years) 42.96 41.36 45.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1502
Matched controls
14918
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
7.2
320.1
752
1832
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
307.7
834
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
+∞
307.7
442
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
307.7
328
*
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
+∞
307.7
385
*
XF620
NOMESCO Finland
Examination of circulation with color method
216.6
307.7
223
12
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
24.8
307.7
317
159
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
44.7
307.7
712
295
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
9.5
307.7
664
1147
B01AA03
ATC
warfarin; systemic
7.9
290.0
506
901
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
41.8
237.3
145
38
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
216.5
203
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
12.9
194.5
199
175
XF400
NOMESCO Finland
ECG with 12 standard connections
5.4
189.7
500
1272
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.7
162.9
294
522
XF404
NOMESCO Finland
Ambulatory ECG
6.5
160.6
300
551
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
6.9
159.0
277
474
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
7.9
156.9
235
341
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
13.6
153.1
149
120
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.0
152.1
907
4105
I48
ICD-10 Finland
Atrial fibrillation and flutter
4.6
133.8
398
1088
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
126.6
120
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
125.5
119
*
C01AA05
ATC
digoxin; systemic
7.3
121.7
192
293
FM2CE, ,
NOMESCO Finland
10.2
121.2
143
153
31
HP
Congenital heart failure surgery
+∞
121.2
115
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
119.1
113
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.1
118.8
415
1269
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
115.9
110
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.8
115.8
236
465
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
15.4
115.2
103
71
WX872
NOMESCO Finland
Intensive care
7.8
112.7
166
234
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.9
109.5
411
1314
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
57.7
98.7
56
10
C03CA01
ATC
furosemide; systemic
3.4
97.3
466
1733
TPH07
NOMESCO Finland
Cathetrisation of artery
4.3
94.1
282
761
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
93.5
89
*
TFP20
NOMESCO Finland
Cardiodefibrillation
5.9
92.2
178
331
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
7.7
87.1
128
179
61
HP
Catheterization and pressure measurement of the left side of the heart
17.6
85.7
71
42
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
7.0
83.6
133
203
207
Kela drug reimbursment
Chronic arrhythmias
4.0
83.0
268
760
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
14.8
77.4
70
49
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
75.1
554
2574
C03DA01
ATC
spironolactone; oral
4.0
73.9
241
685
5205
FHL
ASD blockage, secondary defect
+∞
73.4
70
*
XF402
NOMESCO Finland
ECG with work load test
4.2
72.5
219
589
5253
FHL
Cardiac lung machine
30.7
72.4
48
16
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
12.3
71.1
72
61
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
69.1
66
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
6.5
67.6
116
191
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.1
67.0
151
321
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
344.8
66.9
67
*
WX892
NOMESCO Finland
Monitored bed care
4.0
65.7
204
558
I34.1
ICD-10 Finland
Mitral (valve) prolapse
8.4
65.6
88
110
K78
ICPC
Atrial fibrillation/flutter
5.1
65.5
148
315
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
63.9
695
3834
PA2AE
NOMESCO Finland
Ultrasound examination of brain artery
224.7
63.5
65
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
5.2
61.8
134
275
C07AB07
ATC
bisoprolol; oral
2.5
61.7
673
3701
Q21.1
ICD-10 Finland
Atrial septal defect
+∞
61.7
59
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
11.2
60.6
65
60
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
59.8
284
1022
XFE00
NOMESCO Finland
Epicardial ultrasonography
10.5
59.8
67
66
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
59.6
57
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
59.6
452
2091
I50.9
ICD-10 Finland
Heart failure, unspecified
3.7
59.4
209
622
XA800
NOMESCO Finland
Neuropsychological investigation
4.1
58.6
175
464
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
56.5
54
*
FFC50
NOMESCO Finland
Closure of ostium secundum type ASD using patch
+∞
56.5
54
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
5.6
56.1
112
213
62
HP
Catheterization and pressure measurement of the right side of the heart
71.2
54.4
62
9
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
10.2
54.1
62
63
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
4.3
53.8
150
377
Q23.11
ICD-10 Finland
Bicuspid aortic valve
+∞
53.3
51
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
52.1
601
3328
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
20.4
51.8
40
20
I50.0
ICD-10 Finland
Congestive heart failure
4.9
51.8
120
260
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.4
50.7
202
650
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
17.4
49.5
41
24
XF622
NOMESCO Finland
Measurement of minute volume of heart
92.7
49.0
54
6
R4150
NOMESCO Finland
Neuropsychological rehabilitation
12.2
48.6
49
41
B01AC04
ATC
clopidogrel; oral
3.1
48.2
236
858
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
+∞
48.1
46
*
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
47.0
45
*
APK
HP
ASD closure
+∞
47.0
45
*
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
6.0
46.7
85
148
XF600
NOMESCO Finland
Bloodpressure measurement
3.5
46.2
177
554
AF1
HP
Surgery of congenital heart defect
+∞
46.0
44
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.1
45.7
220
791
R4110
NOMESCO Finland
Physiotherapy
2.3
44.7
501
2705
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.5
43.7
111
259
Z2221
NOMESCO Finland
Medical doctor
2.2
42.6
496
2711
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
16.6
42.5
36
22
Q21.12
ICD-10 Finland
Defective sinus venosus
+∞
41.8
40
*
APJ
HP
PFO closure
+∞
40.7
39
*
C07AA07
ATC
sotalol; systemic
5.8
40.4
75
133
C01BD01
ATC
amiodarone; systemic
6.7
39.4
64
99
XF640, ,
NOMESCO Finland
6.7
39.4
64
99
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
39.4
304
1386
G04BE03
ATC
sildenafil; oral
10.7
39.1
43
41
Q21.21
ICD-10 Finland
Atrioventricular duct
+∞
38.6
37
*
I49.5
ICD-10 Finland
Sick sinus syndrome
5.3
37.9
78
152
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.0
37.9
191
702
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
37.5
360
1805
7456A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[DEFECTUS SEPTI ATRIORUM NUD]
+∞
36.5
35
*
AA1AD
NOMESCO Finland
CT of head and brain
2.2
36.2
374
1928
XX3BT
NOMESCO Finland
Other labeling with X-ray guidance
8.3
36.2
48
59
FFC42
NOMESCO Finland
Percutaneous closure of patent foramen ovale
+∞
34.4
33
*
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
122.0
33.7
36
*
B01AB05
ATC
enoxaparin; parenteral
2.1
33.5
424
2357
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.4
32.2
120
367
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
13.1
32.1
31
24
AN1
HP
Coronary angiography
3.0
31.9
148
517
WX882
NOMESCO Finland
High dependency care
3.3
31.3
127
410
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
+∞
31.3
30
*
B01AF02
ATC
apixaban; oral
2.8
30.4
161
605
I48.2
ICD-10 Finland
Chronic atrial fibrillation
4.6
30.0
72
160
WX402
NOMESCO Finland
General anaesthesia
2.0
29.5
386
2158
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.8
29.2
91
247
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
28.1
27
*
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
28.1
27
*
ZXD05
NOMESCO Finland
Urgent procedure
1.9
27.8
461
2791
K90
ICPC
Stroke/cerebrovascular accident
5.3
27.7
57
111
R4120
NOMESCO Finland
Occupational therapy
2.8
27.7
147
553
AP2
HP
Catheterization of the right side of the heart
47.8
27.4
33
7
K84
ICPC
Heart disease other
5.6
27.1
52
95
Q20.48
ICD-10 Finland
Single ventricle
+∞
27.1
26
*
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
4.5
27.1
68
157
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
273.9
26.7
27
*
Q26.3
ICD-10 Finland
Partial anomalous pulmonary venous connection
+∞
26.0
25
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
25.8
363
2071
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
94.5
25.6
28
*
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
5.5
25.1
49
91
RS224, ,
NOMESCO Finland
7.7
24.9
35
46
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
21.5
24.7
36
17
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
91.0
24.6
27
*
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
9.2
24.6
30
33
I44.2
ICD-10 Finland
Atrioventricular block, complete
5.4
24.1
48
91
FFC96
NOMESCO Finland
Other closure of isolated atrial septal defect
+∞
24.0
23
*
C01BC04
ATC
flecainide; systemic
4.1
23.5
66
166
ZXE00
NOMESCO Finland
One hour or less
1.7
23.2
607
4174
TFP34
NOMESCO Finland
Electrophysiological investigation
3.9
23.1
68
177
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
22.9
22
*
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
+∞
22.9
22
*
PD5BD
NOMESCO Finland
Extensive CT of aorta
7.4
22.8
33
45
Z98.8
ICD-10 Finland
Other specified postsurgical states
6.2
22.7
39
64
R06.0
ICD-10 Finland
Dyspnoea
1.9
22.3
366
2184
C07AB02
ATC
metoprolol; systemic
2.1
22.2
238
1224
Q26.1
ICD-10 Finland
Persistent left superior vena cava
+∞
21.9
21
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.3
21.5
56
133
AP3
HP
Catheterization of the right and left side of the heart
43.7
21.4
26
6
C09AA05
ATC
ramipril; oral
2.0
21.2
284
1582
Z3231
NOMESCO Finland
Registered nurse
1.8
21.1
464
3018
WX704
NOMESCO Finland
Intubation
2.6
21.0
133
546
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
20.8
20
*
Q21.30
ICD-10 Finland
Tetralogy of Fallot
+∞
20.8
20
*
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.8
20.8
109
406
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.3
20.8
54
128
R04.0
ICD-10 Finland
Epistaxis
2.7
20.8
115
441
I35.0
ICD-10 Finland
Aortic (valve) stenosis
3.4
20.7
75
225
TFP35
NOMESCO Finland
Electroanatomical mapping
5.7
20.7
39
70
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.2
20.6
191
927
I50.1
ICD-10 Finland
Left ventricular failure
3.8
20.5
63
169
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
30.3
20.5
27
9
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.3
20.3
169
784
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
20.3
201
1001
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.0
20.3
58
148
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
6.7
20.3
32
48
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.9
20.1
60
158
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
5.1
19.8
42
84
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
19.8
19
*
Q21.29
ICD-10 Finland
Atrioventricular septal defect UNS
+∞
19.8
19
*
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
201.2
19.5
20
*
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.9
19.5
43
89
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.3
19.3
39
75
Z3226
NOMESCO Finland
Physiotherapist
1.8
19.1
320
1912
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
22.7
19.0
27
12
74646
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium primum
+∞
18.7
18
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
18.7
18
*
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
+∞
18.7
18
*
81
HP
Angiography of the heart and coronary arteries
3.2
18.3
72
228
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
18.2
356
2224
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.7
17.9
57
157
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.9
17.8
85
301
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
+∞
17.7
17
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
+∞
17.7
17
*
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
17.7
17
*
K83
ICPC
Heart valve disease NOS
14.7
17.6
29
20
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.3
17.6
66
203
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
180.8
17.5
18
*
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
5.8
17.5
32
56
I48.1
ICD-10 Finland
Persistent atrial fibrillation
3.9
17.4
52
137
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
18.7
17.3
26
14
FFC32
NOMESCO Finland
Percutaneous transluminal closure of sinus venosus type ASD
+∞
16.7
16
*
Q22.5
ICD-10 Finland
Ebstein anomaly
+∞
16.7
16
*
Q90.9
ICD-10 Finland
Down syndrome, unspecified
90.5
16.5
18
*
K80
ICPC
Cardiac arrhythmia NOS
2.4
16.3
112
477
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
6.1
16.3
28
46
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
16.1
146
701
FM1CD
NOMESCO Finland
Very extensive CT of heart
30.2
16.1
21
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
16.0
240
1378
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.2
16.0
139
656
602
Kela drug reimbursment
Children's severe malnutrition
3.9
15.7
47
124
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
+∞
15.6
15
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
+∞
15.6
15
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
+∞
15.6
15
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
15.6
15
*
I47.2
ICD-10 Finland
Ventricular tachycardia
4.7
15.5
36
78
ZXY02
NOMESCO Finland
Neuropsychologist
6.7
15.2
24
36
I48.4
ICD-10 Finland
Atypical atrial flutter
15.1
14.8
24
16
I27.0
ICD-10 Finland
Primary pulmonary hypertension
31.8
14.8
19
6
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
56.9
14.8
17
*
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
6.8
14.8
23
34
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
14.6
201
1121
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
+∞
14.6
14
*
51
HP
Other heart surgery
+∞
14.6
14
*
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
+∞
14.6
14
*
I97.0
ICD-10 Finland
Postcardiotomy syndrome
36.2
14.4
18
5
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
6.6
14.4
23
35
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.9
14.1
41
106
B01AE07
ATC
dabigatran etexilate; oral
3.5
14.0
49
144
Q87.14
ICD-10 Finland
Noonan's syndrome
53.5
13.8
16
*
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
20.1
13.7
20
10
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
14.8
13.5
22
15
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
+∞
13.5
13
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
+∞
13.5
13
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
18.3
13.3
20
11
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.4
13.0
88
372
I44.1
ICD-10 Finland
Atrioventricular block, second degree
4.7
13.0
30
65
GE1BE
NOMESCO Finland
Mediastinal ultrasound examinaiton through oesophagus
28.4
12.9
17
6
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
4.2
12.9
34
82
WX002
NOMESCO Finland
Sedation and analgesia
1.7
12.6
240
1473
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
3.1
12.6
54
180
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
4.2
12.6
33
79
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
70.0
12.6
14
*
R50.9
ICD-10 Finland
Fever, unspecified
1.7
12.5
262
1652
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
4.8
12.5
28
59
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
+∞
12.5
12
*
Q21.2
ICD-10 Finland
Atrioventricular septal defect
+∞
12.5
12
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
12.5
12
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
+∞
12.5
12
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
130.2
12.4
13
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
12.4
624
4814
250, ,
Kela drug reimbursment
6.2
12.4
21
34
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
5.0
12.3
26
52
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
11.7
12.3
22
19
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
12.2
422
3003
J01CA04
ATC
amoxicillin; systemic
1.7
12.2
1260
11277
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
12.1
298
1957
AC4
HP
MVP
26.7
12.0
16
6
I44.0
ICD-10 Finland
Atrioventricular block, first degree
5.7
11.9
22
39
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
46.7
11.8
14
*
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
65.0
11.6
13
*
AD1
HP
TVP
65.0
11.6
13
*
K99
ICPC
Cardiovascular disease other
4.0
11.6
32
80
Z2445
NOMESCO Finland
Psychologist
2.1
11.5
115
573
R62.0
ICD-10 Finland
Delayed milestone
2.8
11.5
57
207
C10AA05
ATC
atorvastatin; oral
1.5
11.5
409
2926
H53.4
ICD-10 Finland
Visual field defects
3.9
11.5
33
85
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
+∞
11.4
11
*
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
11.4
11
*
I51.0
ICD-10 Finland
Cardiac septal defect, acquired
+∞
11.4
11
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
11.4
11
*
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
11.4
11
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
11.4
11
*
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
+∞
11.4
11
*
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
+∞
11.4
11
*
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
4.2
11.4
30
72
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
120.1
11.4
12
*
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
120.1
11.4
12
*
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.1
11.3
47
154
K77
ICPC
Heart failure
4.2
11.2
29
69
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
4.5
10.9
26
58
7AX01, ,
NOMESCO Finland
15.5
10.8
17
11
R42
ICD-10 Finland
Dizziness and giddiness
1.6
10.7
266
1747
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
10.7
90
419
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
4.9
10.6
23
47
R1260
NOMESCO Finland
Evaluation of communicative skills
3.3
10.5
39
120
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.1
10.4
101
497
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
10.4
10
*
APX
HP
Other cardiac catheter operation
+∞
10.4
10
*
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
10.4
10
*
Q24.6
ICD-10 Finland
Congenital heart block
+∞
10.4
10
*
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
10.4
10
*
Q25.3
ICD-10 Finland
Stenosis of aorta
110.0
10.4
11
*
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
3.8
10.4
31
82
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
32.5
10.3
13
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.1
10.3
104
521
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
7.5
10.1
23
31
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.3
10.1
79
357
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
10.1
114
594
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
3.0
10.0
44
150
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.0
9.9
43
145
FM1AD
NOMESCO Finland
CT of heart
16.7
9.8
15
9
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.7
9.8
52
196
F83
ICD-10 Finland
Mixed specific developmental disorders
2.9
9.8
45
157
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
26.0
9.8
13
5
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
26.0
9.8
13
5
WW502
NOMESCO Finland
Autotransfusion
10.6
9.7
18
17
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
10.6
9.7
18
17
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.1
9.7
41
136
C01BD07
ATC
dronedarone; oral
9.5
9.7
19
20
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.7
9.7
53
203
FM1BD
NOMESCO Finland
Extensive CT of heart
11.4
9.5
17
15
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
11.4
9.5
17
15
342
Kela drug reimbursment
Dronedarone
8.4
9.5
20
24
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
9.1
9.5
19
21
I63
ICD-10 Finland
Cerebral infarction
9.1
9.5
19
21
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
100.0
9.4
10
*
3A064, ,
NOMESCO Finland
17.5
9.4
14
8
AE1
HP
Pulmonary artery thrombendarterectomy
+∞
9.4
9
*
Q24.0
ICD-10 Finland
Dextrocardia
+∞
9.4
9
*
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
9.4
9
*
5207
FHL
VSD closure
+∞
9.4
9
*
FDE10
NOMESCO Finland
Ligature of patent ductus arteriosus
+∞
9.4
9
*
Q90
ICD-10 Finland
Down syndrome
+∞
9.4
9
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
21.7
9.3
13
6
ZX199
NOMESCO Finland
Other rote
6.9
9.3
22
32
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.4
9.3
63
268
Z31.5
ICD-10 Finland
Genetic counselling
2.0
9.3
104
541
GD1LA
NOMESCO Finland
GD
4.1
9.2
25
62
73
HP
Initial pacemaker installation
13.7
9.1
15
11
UGC02
NOMESCO Finland
Rigid bronchoscopy
7.7
9.1
20
26
L04AD02
ATC
tacrolimus; systemic
3.5
9.0
30
86
I49.1
ICD-10 Finland
Atrial premature depolarization
2.6
8.9
50
194
C09AA02
ATC
enalapril; systemic
1.7
8.9
183
1144
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
2.6
8.8
50
195
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
4.9
8.8
19
39
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
8.7
154
925
TKC20
NOMESCO Finland
Catheterisation of bladder
2.2
8.6
70
323
K91
ICPC
Cerebrovascular disease
4.8
8.5
19
40
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
27.5
8.5
11
*
C02KX01
ATC
bosentan; oral
27.5
8.5
11
*
AB2
HP
AVR bio, stent
20.0
8.4
12
6
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
8.4
212
1393
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
7.3
8.4
19
26
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
8.4
401
3015
GD1AD
NOMESCO Finland
Thorax CT examination
2.2
8.3
69
320
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
8.3
8
*
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
+∞
8.3
8
*
7456C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[ASD CANALIS ATRIOVENTRICULARIS COMMUNIS]
+∞
8.3
8
*
Q21.80
ICD-10 Finland
Communication from left ventricle to right atrium
+∞
8.3
8
*
FGD00
NOMESCO Finland
Repair of tricuspid valve using suture
+∞
8.3
8
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
+∞
8.3
8
*
1EA01, ,
NOMESCO Finland
+∞
8.3
8
*
127
Kela drug reimbursment
Transplant complication
2.9
8.3
37
127
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
8.5
8.3
17
20
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
4.0
8.3
23
58
Z2446
NOMESCO Finland
Social worker
1.7
8.2
152
923
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.7
8.2
44
167
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
7.1
8.2
19
27
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
7.1
8.2
19
27
FKC60
NOMESCO Finland
Resection and reconstruction of leaflet of mitral valve for insufficiency
14.5
8.2
13
9
AP1
HP
Catheterization of the left side of the heart
3.9
8.1
23
59
FFW96
NOMESCO Finland
Other operation on atria
33.3
8.1
10
*
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
4.7
8.0
18
38
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
10.0
8.0
15
15
RS221, ,
NOMESCO Finland
2.9
8.0
37
130
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
8.0
210
1395
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.3
7.9
59
262
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.2
7.9
31
99
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
7.9
103
565
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.0
7.8
89
465
PA7BD
NOMESCO Finland
CT angiography of neck and brain
3.9
7.8
22
56
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
10.8
7.8
14
13
RK260, ,
NOMESCO Finland
10.8
7.8
14
13
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
3.8
7.7
23
61
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
3.0
7.7
33
111
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
15.0
7.7
12
8
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
7.6
1007
11007
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.5
7.6
47
192
ZX120
NOMESCO Finland
Intravenous
1.8
7.5
121
706
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
25.0
7.5
10
*
1CX08, ,
NOMESCO Finland
11.8
7.5
13
11
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
7.5
251
1755
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.5
7.5
47
193
A02BC02
ATC
pantoprazole; systemic
1.3
7.5
773
6563
ZX108
NOMESCO Finland
Inhalation
4.1
7.5
20
49
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.4
7.5
26
77
FFC40
NOMESCO Finland
Closure of Patent Foramen Ovale
79.9
7.4
8
*
90492, ,
NOMESCO Finland
79.9
7.4
8
*
Z94.1
ICD-10 Finland
Heart transplant status
7.6
7.4
16
21
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
3.4
7.3
25
73
WX870
NOMESCO Finland
Other postsurgical intensive care
8.3
7.3
15
18
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.7
7.3
37
137
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
7.3
7
*
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
+∞
7.3
7
*
FFF96
NOMESCO Finland
Other operation for partially anomalous pulmonary veins
+∞
7.3
7
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
7.3
7
*
FK1AC
NOMESCO Finland
Right cardioangiography
+∞
7.3
7
*
Q21
ICD-10 Finland
Congenital malformations of cardiac septa
+∞
7.3
7
*
FHB00
NOMESCO Finland
Transatrial suture of VSD
+∞
7.3
7
*
FFF20
NOMESCO Finland
Anastomosis to left atrium from partially anomalous pulmonary veins
+∞
7.3
7
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
+∞
7.3
7
*
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
+∞
7.3
7
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
7.3
7
*
Q20.60
ICD-10 Finland
Left isomerism of atrial appendages
+∞
7.3
7
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
+∞
7.3
7
*
B01AF01
ATC
rivaroxaban; oral
1.7
7.2
122
723
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
2.3
7.2
52
228
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
7.2
123
731
I21.19
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
5.8
7.2
19
33
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
7.2
93
509
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
30.0
7.1
9
*
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
20.0
7.1
10
5
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
7.1
358
2706
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.3
7.0
26
80
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.5
7.0
41
163
AAL10
NOMESCO Finland
Intracranial endovascular thrombolysis
10.0
7.0
13
13
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.8
7.0
34
123
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
6.9
324
2414
R07.2
ICD-10 Finland
Precordial pain
3.2
6.9
26
81
R00.2
ICD-10 Finland
Palpitations
1.8
6.9
103
589
C10AA01
ATC
simvastatin; oral
1.4
6.9
363
2764
C08DA01
ATC
verapamil; systemic
2.3
6.8
50
221
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
6.8
120
720
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.2
6.8
56
260
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
40.0
6.7
8
*
I48.3
ICD-10 Finland
Typical atrial flutter
5.6
6.7
18
32
742, ,
NOMESCO Finland
22.5
6.7
9
*
J96.1
ICD-10 Finland
Chronic respiratory failure
3.3
6.6
24
73
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
6.6
81
436
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
5.5
6.6
18
33
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.1
6.6
58
277
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.6
6.5
37
145
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.9
6.5
81
438
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
6.5
275
2013
H65.3
ICD-10 Finland
Chronic mucoid otitis media
1.9
6.5
76
403
P07.3
ICD-10 Finland
Other preterm infants
2.7
6.4
33
123
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
3.6
6.4
20
55
Q90.1
ICD-10 Finland
Trisomy 21, mosaicism (mitotic nondisjunction)
69.7
6.4
7
*
FGE10
NOMESCO Finland
Replacement of tricuspid valve using biological prosthesis
69.7
6.4
7
*
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
69.7
6.4
7
*
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.4
456
3639
FKD00
NOMESCO Finland
Replacement of mitral valve using mechanical prosthesis
14.3
6.4
10
7
M41.9
ICD-10 Finland
Scoliosis, unspecified
3.4
6.4
22
65
3AC01, ,
NOMESCO Finland
4.1
6.3
17
42
R47.0
ICD-10 Finland
Dysphasia and aphasia
5.5
6.3
17
31
I50
ICD-10 Finland
Heart failure
2.8
6.3
30
108
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
+∞
6.2
6
*
FM2FN
NOMESCO Finland
Intra cardiac shunt isotope imaging
+∞
6.2
6
*
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
6.2
6
*
0034, ,
NOMESCO Finland
+∞
6.2
6
*
FMC96
NOMESCO Finland
Other operation on aortic valve for insufficiency
+∞
6.2
6
*
Q21.88
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
6.2
6
*
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
+∞
6.2
6
*
Q89.30
ICD-10 Finland
Situs inversus with dextrocardia
+∞
6.2
6
*
K73
ICPC
Congenital anomaly cardiovascular
+∞
6.2
6
*
Q21.8
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
6.2
6
*
FDE32
NOMESCO Finland
Percutaneous transluminal closure of patent ductus arteriosus
+∞
6.2
6
*
3AE00, ,
NOMESCO Finland
+∞
6.2
6
*
ZF61V, ,
NOMESCO Finland
+∞
6.2
6
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
6.2
6
*
7456B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[DEFECTUS SEPTI ATRIORUM, OSTII PRIMII]
+∞
6.2
6
*
Q21.15
ICD-10 Finland
Common atrium
+∞
6.2
6
*
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
+∞
6.2
6
*
H50.30
ICD-10 Finland
Intermittent esotropy
3.5
6.2
21
61
A12BA01
ATC
potassium chloride; oral
2.4
6.2
40
167
FN1AD
NOMESCO Finland
CT of coronary arteries
3.3
6.2
23
71
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
2.9
6.2
27
92
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
2.8
6.2
29
103
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.9
6.2
76
409
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
1.9
6.2
78
424
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.0
6.1
61
305
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
6.1
82
454
D68.8
ICD-10 Finland
Other specified coagulation defects
3.5
6.1
20
57
FP1C5
NOMESCO Finland
Resting ECG, 15 leads
3.5
6.1
20
57
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
12.5
6.1
10
8
FKC96
NOMESCO Finland
Other repair of mitral valve for insufficiency
12.5
6.1
10
8
AS4
HP
Physiological pacemaker insertion DDD (R)
4.1
6.0
16
39
42792
ICD-8 Finland
Symptomatic heart disease, Fibrillatio auricularis
8.6
6.0
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
564
1720
4.61
168.61
3.6
3.5
30.96
29.92
s
3.08
554
1675
677
2410
4.26
163.45
5.9
3.2
1170.63
1063.68
ng/l
0.33
617
1997
955
4349
4.24
161.81
28.3
11.1
1.56
1.18
inr
13.38
220
1317
301
673
5.30
128.94
3.6
3.4
221.31
176.45
ng/l
0.72
264
601
261
556
5.43
117.61
3.2
5.0
21.62
22.09
s
0.69
220
517
655
2956
3.13
98.91
6.0
5.3
80.65
91.82
%
21.11
648
2886
616
2707
3.14
97.10
2.5
2.6
—
—
—
0
0
138
200
7.45
91.07
1.3
1.3
4.00
4.86
u/ml
0.29
67
92
471
1842
3.24
89.55
4.1
3.5
1333.51
462.48
ng/l
2.13
376
1260
689
3481
2.78
80.57
2.7
2.6
—
—
—
0
0
877
5190
2.63
71.97
3.0
2.7
—
—
—
0
0
57
39
15.05
63.67
1.2
1.4
—
—
—
0
0
223
734
3.37
54.10
2.2
2.3
15.70
6.75
ug/l
3.82
200
641
389
1757
2.62
53.03
6.8
6.3
0.82
0.81
mmol/l
0.58
374
1667
1036
7295
2.32
48.87
5.0
3.3
—
—
—
0
0
552
3016
2.29
48.69
2.7
2.3
243.52
250.25
u/l
0.05
527
2867
163
485
3.62
45.99
4.5
5.8
3.01
3.26
g/l
1.63
158
466
974
6855
2.17
43.49
8.0
5.5
6.18
6.47
mmol/l
6.23
932
6392
36
29
12.61
36.46
4.0
8.1
—
—
—
0
0
35
27
13.16
36.36
3.7
8.1
—
—
—
0
0
569
3572
1.94
31.54
4.6
3.2
58.91
44.73
ng/l
0.37
393
2203
235
1054
2.44
31.07
15.3
9.0
5.31
5.15
kpa
1.38
230
1013
235
1054
2.44
31.07
15.3
9.0
13.20
12.71
kpa
0.57
230
1017
234
1058
2.42
30.35
15.3
9.0
1.21
0.97
mmol/l
0.44
207
850
143
508
2.98
29.92
21.1
12.4
—
—
—
0
0
45
71
6.46
27.19
1.0
1.1
1.08
1.05
ratio
—
6
32
1388
12088
2.85
27.05
23.1
14.3
139.48
139.57
mmol/l
0.77
1380
11769
752
5334
1.80
27.02
12.5
8.4
1.20
1.22
mmol/l
8.60
713
4936
1389
12111
2.85
26.82
23.2
14.4
3.97
3.95
mmol/l
1.67
1380
11764
279
1428
2.16
26.71
15.0
10.3
—
—
—
0
0
419
2551
1.88
24.27
3.1
2.5
1.21
1.25
mg/l
0.11
306
1910
147
602
2.58
23.34
20.0
10.8
0.68
0.69
%
0.23
147
597
147
605
2.57
23.10
19.8
10.8
1.25
1.36
%
0.82
147
599
28
7
40.49
22.63
2.6
4.4
—
—
—
0
0
272
1467
2.03
22.34
15.8
12.7
25.42
24.60
mmol/l
5.98
272
1461
777
5790
1.69
21.58
11.1
8.6
1.21
1.22
mmol/l
5.90
697
5077
277
1532
1.98
21.09
3.3
2.7
21.12
22.86
%
1.55
257
1364
754
5612
1.67
20.72
8.6
6.8
16.70
13.97
umol/l
2.11
710
5304
290
1646
1.93
20.41
3.2
2.6
2.44
2.42
g/l
0.17
274
1540
310
1799
1.90
20.40
3.2
2.6
12.75
13.70
umol/l
1.60
293
1694
314
1835
1.88
20.20
8.7
8.2
1.21
1.17
mmol/l
1.28
305
1728
1382
12313
2.44
20.14
18.7
12.6
23.59
22.15
mg/l
0.96
1150
9315
642
4614
1.67
19.96
5.9
5.7
36.33
36.34
g/l
0.02
601
4333
524
3583
1.69
19.61
1.4
1.5
—
—
—
0
0
81
267
3.13
19.23
5.7
9.9
—
—
—
0
0
415
2697
1.73
18.52
4.6
4.3
—
—
—
0
0
802
6187
1.62
18.17
7.4
8.0
—
—
—
0
0
218
1165
2.00
18.13
10.2
8.1
—
—
—
0
0
840
6578
1.61
17.69
7.0
7.4
0.58
0.57
e9/l
0.87
728
5621
859
6771
1.61
17.53
7.0
7.5
1.88
2.10
e9/l
5.16
761
5938
411
2703
1.70
17.39
5.8
3.4
—
—
—
0
0
838
6579
1.60
17.29
7.0
7.5
0.04
0.04
e9/l
0.86
727
5620
101
407
2.57
16.53
2.4
2.1
1.17
1.44
g/l
2.24
85
361
57
166
3.51
16.51
8.4
6.7
11.75
11.18
mg/l
0.29
49
154
248
1428
1.87
16.43
9.9
7.7
7.40
7.41
ph
0.20
18
90
269
1601
1.81
16.00
6.4
7.8
1.37
1.44
mmol/l
0.13
231
1297
853
6795
1.57
15.98
7.5
8.0
0.19
0.20
e9/l
1.90
752
5902
49
135
3.69
15.42
3.0
3.0
0.80
0.84
nmol/l
0.21
37
107
776
6082
1.55
15.38
7.4
7.7
0.65
0.66
%
0.17
741
5765
1398
12750
2.29
15.26
17.7
11.1
—
—
—
0
0
796
6300
1.54
14.91
7.4
7.9
8.77
8.38
%
3.16
762
5982
213
1212
1.87
14.55
7.0
8.6
23.95
23.65
mmol/l
0.83
213
1203
815
6514
1.53
14.37
7.3
7.6
28.56
31.31
%
9.75
781
6202
788
6268
1.52
14.10
7.3
7.6
2.88
3.00
%
0.74
754
5944
428
2985
1.59
13.84
2.8
2.5
3.19
2.85
mg/l
1.50
383
2585
32
72
4.49
13.20
2.0
1.3
—
—
—
0
0
31
68
4.60
13.19
2.1
1.3
27184.76
32038.62
e6/l
0.12
21
37
798
6423
1.50
13.10
7.0
7.4
56.12
53.71
%
6.66
766
6114
488
3564
1.53
12.66
6.9
8.1
—
—
—
0
0
895
7430
1.49
12.22
9.2
10.2
3.85
3.86
e9/l
0.06
788
6385
1023
8737
1.51
12.07
4.7
4.1
10.40
10.46
mm/h
0.05
979
8150
31
75
4.17
11.69
2.1
1.3
1520.30
1851.06
e6/l
0.22
23
51
522
3920
1.49
11.65
4.2
3.8
33.01
32.72
u/l
0.03
495
3741
743
5986
1.46
11.56
10.1
10.2
0.00
0.00
e9/l
0.11
593
4767
42
128
3.32
11.41
5.5
16.8
11.48
11.20
%
0.28
42
128
1001
8567
1.48
11.22
8.4
7.0
88.74
89.65
u/l
0.16
956
8064
113
566
2.06
11.13
6.1
5.6
—
—
—
0
0
222
1383
1.70
11.00
3.4
4.6
1.87
1.63
%
1.98
207
1272
421
3055
1.51
10.96
4.3
3.9
7.40
7.40
ph
0.05
85
562
227
1437
1.67
10.57
4.8
4.6
8.51
7.48
umol/l
0.44
207
1214
237
1528
1.64
10.27
2.6
2.0
—
—
—
0
0
700
5660
1.43
10.22
3.7
3.0
108.77
96.28
ug/l
0.84
658
5302
135
751
1.86
9.82
2.1
3.0
65.02
66.42
g/l
0.97
122
692
18
19
9.51
9.23
1.1
1.1
—
—
—
0
0
25
63
3.99
8.97
2.1
1.3
—
—
—
0
0
162
1006
1.67
8.07
3.1
3.7
77.48
68.99
e9/l
1.58
115
710
29
89
3.28
7.86
41.8
41.4
7.19
6.71
ug/l
0.69
29
80
93
495
1.92
7.77
1.1
1.5
—
11.29
—
0
12
934
8144
1.37
7.70
4.6
4.2
—
—
—
0
0
1228
11248
1.46
7.34
22.4
15.8
14.49
14.33
%
0.51
1217
11066
231
1608
1.50
7.05
1.7
1.7
1151.31
1198.25
nmol/l
0.33
175
1215
50
224
2.26
6.62
6.7
5.0
1.64
2.31
mmol/l
1.54
31
139
433
3413
1.37
6.60
3.8
3.5
0.45
0.38
e6/l
0.31
340
2561
533
4370
1.33
6.17
4.5
4.1
40.00
83.98
e6/l
1.91
385
3000
17
32
5.32
6.12
1.1
1.1
—
—
—
0
0
94
558
1.72
5.57
1.8
2.3
—
—
—
0
0
118
745
1.62
5.54
3.1
3.2
4.48
4.76
pmol/l
1.85
106
672
420
3371
1.33
5.52
3.8
3.4
—
—
—
0
0
455
3696
1.32
5.50
4.0
3.6
238.06
70.92
e6/l
0.38
360
2812
23
77
3.00
5.47
6.9
5.3
115.00
73.22
mg/l
0.58
18
68
1449
13935
1.93
5.36
27.7
18.5
89.76
89.38
fl
2.10
1442
13759
23
78
2.96
5.36
2.3
1.6
—
—
—
0
0
1448
13923
1.92
5.35
29.4
18.8
39.65
40.43
%
1.42
1393
13208
1449
13938
1.92
5.31
27.6
18.4
29.92
29.86
pg
0.57
1442
13762
869
7704
1.29
5.31
4.7
4.1
234.20
2640.84
e6/l
1.64
15
96
1198
11095
1.36
5.28
5.2
4.5
1.96
2.10
mu/l
0.41
1126
10316
1449
13940
1.92
5.28
27.8
18.5
4.49
4.54
e12/l
3.85
1422
13463
1449
13941
1.92
5.26
27.8
18.5
6.76
6.76
e9/l
0.01
1425
13461
15
30
5.01
5.22
1.1
12.1
—
—
—
0
0
279
2120
1.38
5.22
2.7
3.0
0.90
0.99
e6/l
0.16
158
1188
1448
13931
1.90
5.22
27.8
18.5
246.64
259.74
e9/l
11.70
1425
13494
67
367
1.85
5.21
1.4
1.3
—
—
—
0
0
46
221
2.10
5.19
3.0
2.7
17.20
16.67
%
0.41
27
128
1449
13946
1.91
5.18
28.7
18.6
133.03
135.02
g/l
5.37
1443
13767
415
3352
1.32
5.17
2.9
2.6
62.19
82.54
u/l
0.40
387
3118
231
1706
1.41
5.12
1.4
1.4
734.88
505.93
titre
0.80
43
327
291
2240
1.36
5.01
1.6
1.5
20.87
20.90
nmol/l
0.01
260
1931
67
372
1.83
5.01
3.8
3.5
—
—
—
0
0
318
2511
1.33
4.59
3.4
2.8
5.10
6.43
e6/l
1.12
291
2236
16
48
3.34
4.56
1.6
1.1
10.25
11.84
u/l
0.22
16
43
65
369
1.78
4.55
5.6
5.4
—
—
—
0
0
19
64
2.97
4.50
5.1
3.4
—
—
—
0
0
439
3631
1.28
4.48
3.0
3.2
2.36
2.37
mmol/l
0.19
388
3253
1070
9842
1.28
4.37
5.1
5.0
37.87
39.00
mmol/mol
4.64
1008
9235
46
238
1.95
4.30
5.7
4.2
—
—
—
0
0
28
120
2.34
4.20
2.5
2.4
31.79
32.62
pg
0.33
28
120
180
1321
1.40
4.13
1.8
1.5
—
—
—
0
0
478
4028
1.26
4.13
2.1
1.8
99.68
96.31
pmol/l
0.84
270
2091
197
1471
1.38
4.08
2.1
1.7
—
—
—
0
0
48
257
1.88
4.07
1.5
2.1
37.64
38.29
g/l
0.24
41
234
323
2607
1.29
3.93
3.7
3.0
2564.26
5299.36
umol/l
0.60
289
2320
864
7800
1.24
3.92
4.0
3.5
47.69
44.13
u/l
0.74
825
7389
43
225
1.92
3.91
4.5
4.6
—
—
—
0
0
1201
11268
1.29
3.83
23.2
16.2
333.31
333.41
g/l
0.15
1196
11177
26
113
2.31
3.80
5.3
4.6
—
—
—
0
0
27
120
2.26
3.75
2.4
3.5
—
—
—
0
0
51
289
1.78
3.65
2.0
2.0
11.01
10.39
g/l
0.31
44
265
150
1092
1.40
3.62
2.4
2.4
38.14
83.34
u/l
0.50
131
911
74
466
1.61
3.60
1.4
1.6
1.12
1.18
g/l
0.83
68
445
259
2055
1.30
3.57
3.0
3.2
3.17
2.53
e6/l
0.39
140
1134
15
51
2.94
3.53
1.5
1.9
—
—
—
0
0
28
130
2.16
3.53
1.2
1.1
—
—
—
0
0
130
932
1.42
3.43
5.8
5.5
77.58
69.00
ng/l
1.10
115
864
9
18
4.99
3.35
1.7
1.7
38.58
21.45
g/l
—
9
13
1020
9446
1.23
3.33
4.5
3.9
14.84
14.58
pmol/l
2.79
948
8675
46
262
1.77
3.26
5.9
3.8
3.86
3.86
mmol/l
0.05
46
257
25
115
2.18
3.24
2.4
2.2
—
—
—
0
0
297
2431
1.27
3.20
3.8
3.0
553.69
553.21
mosm/kgh2o
0.01
269
2098
391
3307
1.24
3.15
2.9
2.8
—
—
—
0
0
143
1059
1.38
3.14
1.2
1.4
151.13
304.62
u/ml
2.27
136
989
1327
12703
1.32
3.03
12.3
9.9
26.01
26.52
u/l
0.40
1298
12297
123
894
1.40
3.03
4.6
4.8
1.04
0.90
%
0.22
49
327
118
853
1.41
3.00
4.7
4.9
0.20
0.10
%
0.53
43
284
114
822
1.41
2.95
4.2
4.5
0.77
0.60
%
0.47
42
283
32
169
1.90
2.90
1.9
1.7
—
—
—
0
0
111
799
1.41
2.90
3.6
3.5
—
—
—
0
0
69
454
1.53
2.84
1.4
1.6
0.21
0.23
g/l
0.57
64
435
112
813
1.40
2.80
4.8
5.0
0.09
0.50
%
0.57
35
238
61
392
1.57
2.79
1.1
1.2
—
—
—
0
0
27
497
0.53
2.78
1.0
1.2
3.35
3.32
u/ml
0.00
18
347
340
2868
1.23
2.78
3.3
3.4
—
—
—
0
0
22
105
2.10
2.65
1.8
1.7
65.50
54.16
%
0.98
16
76
189
1498
1.29
2.64
1.2
1.3
—
—
—
0
0
17
73
2.33
2.61
1.8
1.5
25.20
36.29
%
—
10
51
26
134
1.94
2.56
1.5
3.8
—
—
—
0
0
8
20
3.99
2.55
2.1
2.1
—
—
—
0
0
16
68
2.35
2.52
1.1
1.1
226.88
222.86
iu/ml
0.02
16
68
219
1779
1.26
2.51
2.4
2.8
2.42
2.44
mmol/l
1.79
184
1546
55
356
1.55
2.47
2.6
2.0
0.75
2.13
ug/l
0.94
49
318
20
96
2.08
2.39
1.2
1.1
—
—
—
0
0
27
146
1.85
2.33
5.1
4.0
—
—
—
0
0
1115
10552
1.19
2.32
4.5
3.9
5.70
5.80
mmol/l
2.35
1038
9702
50
323
1.56
2.28
1.2
1.3
3.52
11.52
u/ml
0.92
14
42
93
680
1.38
2.27
1.2
1.2
—
—
—
0
0
160
1269
1.28
2.24
1.2
1.2
—
—
—
0
0
49
317
1.55
2.23
1.3
1.3
2.10
5.04
u/ml
—
9
28
31
511
0.59
2.21
1.0
1.2
1.41
0.98
u/ml
0.15
16
333
32
523
0.60
2.21
1.0
1.2
2.91
5.67
u/ml
0.79
20
370
535
4798
1.17
2.16
3.2
3.2
5.92
5.99
ph
0.19
40
487
12
48
2.49
2.16
1.6
1.2
—
—
—
0
0
12
48
2.49
2.16
1.6
1.2
—
—
—
0
0
12
48
2.49
2.16
1.6
1.2
—
—
—
0
0
145
1142
1.29
2.15
3.4
3.3
10.16
9.73
g/l
0.46
137
1071
42
265
1.59
2.13
3.2
2.5
136.88
131.02
g/l
0.85
33
205
7
19
3.67
2.13
8.1
9.8
—
—
—
0
0
97
1267
0.74
2.13
1.7
1.7
—
—
—
0
0
641
5836
1.16
2.11
3.6
3.5
0.00
0.00
estimate
0.50
109
1107
49
322
1.53
2.10
5.8
3.9
1.16
1.37
mmol/l
1.76
49
314
23
123
1.87
2.08
1.5
1.3
—
—
—
0
0
5
10
4.98
2.06
2.4
1.8
—
—
—
0
0
473
4215
1.17
2.05
2.0
2.0
—
—
—
0
0
45
292
1.55
2.04
2.7
2.5
—
—
—
0
0
36
560
0.63
2.04
1.1
1.2
6.71
3.27
u/ml
0.34
21
389
234
1962
1.22
2.02
1.3
1.3
16.94
28.25
iu/ml
3.56
68
585
1139
10842
1.18
2.02
4.6
4.0
4.34
4.69
mmol/l
25.12
1083
10193
48
317
1.52
2.02
2.1
1.8
5.23
5.39
iu/l
0.02
17
111
15
297
0.50
2.01
1.0
1.1
0.02
0.34
u/ml
—
6
141
8
26
3.07
2.00
2.4
1.8
—
—
—
0
0
45
294
1.54
1.99
4.3
4.0
9.62
9.83
umol/l
0.02
32
236
34
209
1.63
1.94
1.3
2.3
78.62
72.46
mmol/l
0.24
26
183
5
11
4.53
1.93
1.4
1.3
—
—
—
0
0
73
529
1.39
1.92
4.3
5.8
0.24
0.31
g/l
0.45
49
318
17
317
0.53
1.91
1.1
1.1
5.42
9.06
u/ml
—
8
171
30
180
1.67
1.88
2.0
1.6
—
—
—
0
0
19
339
0.55
1.85
1.1
1.1
1.87
7.87
u/ml
—
10
206
11
43
2.55
1.84
1.2
1.2
—
—
—
0
0
334
2920
1.17
1.83
1.6
1.7
1.32
1.38
mmol/l
0.58
288
2523
15
73
2.05
1.78
1.0
1.3
—
—
—
0
0
8
29
2.75
1.77
2.4
2.2
—
—
—
0
0
1087
10358
1.15
1.71
4.3
3.6
1.19
1.28
mmol/l
4.82
1020
9652
27
163
1.66
1.68
1.1
1.8
—
—
—
0
0
102
1274
0.78
1.65
1.3
1.3
—
—
—
0
0
1144
10963
1.15
1.57
5.0
4.3
2.57
2.81
mmol/l
16.25
1075
10244
115
920
1.26
1.57
5.6
4.2
—
—
—
0
0
37
248
1.49
1.51
4.7
4.3
55.57
55.80
%
0.03
37
248
108
863
1.26
1.49
2.8
4.3
3.65
16.64
ug/l
1.51
88
696
46
324
1.42
1.47
1.4
3.2
—
—
—
0
0
1124
10775
1.14
1.47
4.6
3.9
1.41
1.46
mmol/l
4.15
1063
10080
15
79
1.89
1.47
1.2
1.1
—
—
—
0
0
99
786
1.27
1.45
1.5
1.5
—
—
—
0
0
9
38
2.36
1.45
1.1
1.5
66.87
85.84
nmol/24h
—
9
38
5
16
3.11
1.43
1.6
1.5
—
—
—
0
0
29
187
1.55
1.42
8.4
4.4
—
—
—
0
0
6
22
2.72
1.42
1.3
1.7
—
—
—
0
0
635
5894
1.12
1.41
3.7
3.5
0.00
0.01
estimate
0.80
102
1027
19
110
1.72
1.40
1.3
2.0
—
—
—
0
0
9
40
2.24
1.39
1.2
1.4
—
—
—
0
0
629
5848
1.12
1.34
5.0
4.8
0.00
0.00
estimate
0.50
106
1067
48
348
1.38
1.33
1.4
2.8
3.60
3.54
mmol/l
0.16
43
332
9
42
2.13
1.32
1.1
1.4
176.33
171.20
mmol/24h
—
9
42
8
35
2.28
1.26
2.5
2.3
—
—
—
0
0
6
25
2.39
1.23
1.5
1.1
—
—
—
0
0
18
107
1.68
1.23
1.7
1.7
—
—
—
0
0
27
178
1.52
1.23
1.9
4.0
—
—
—
0
0
49
363
1.35
1.21
1.4
1.4
266.24
319.40
ug/g
0.88
25
210
8
37
2.15
1.20
1.1
1.6
—
—
—
0
0
213
1867
1.16
1.15
1.3
1.2
10.94
8.95
u/ml
0.14
75
685
106
875
1.22
1.14
2.2
2.3
21.70
23.09
au/ml
—
8
71
369
3357
1.12
1.13
1.5
1.6
2.07
2.04
g/l
0.11
225
1892
65
508
1.28
1.13
2.4
2.5
—
—
—
0
0
34
242
1.40
1.09
4.1
3.8
4.12
4.12
e9/l
0.00
34
242
46
346
1.33
1.06
1.5
3.1
178.86
536.99
e6/l
0.77
37
270
46
346
1.33
1.06
1.5
3.0
2.06
7.72
e6/l
1.81
36
263
23
334
0.68
1.05
4.7
2.2
0.83
0.71
nmol/l
0.32
18
286
25
169
1.48
1.04
1.4
1.2
—
—
—
0
0
33
237
1.39
1.01
2.0
3.7
51.05
73.16
mg/l
0.35
25
187
33
237
1.39
1.01
2.0
3.7
32.04
43.86
mg/l
0.41
25
188
30
213
1.41
0.99
1.3
1.1
—
—
—
0
0
60
475
1.27
0.97
1.0
1.1
—
—
—
0
0
32
231
1.38
0.96
1.9
1.7
12377.08
13706.12
e6/l
0.09
24
176
99
829
1.20
0.96
2.5
2.8
5.11
5.96
e9/l
0.28
84
721
145
1645
0.86
0.95
1.6
1.7
—
—
—
0
0
24
168
1.43
0.87
1.0
1.4
—
—
—
0
0
326
2993
1.10
0.85
4.1
3.7
0.00
0.01
estimate
1.28
101
1039
15
226
0.66
0.85
1.1
1.5
10.29
15.54
u/ml
—
6
145
8
44
1.81
0.85
1.6
1.2
—
—
—
0
0
81
675
1.20
0.85
1.9
2.3
7442.84
4766.18
u/l
0.27
27
250
8
45
1.77
0.83
1.3
1.5
—
—
—
0
0
62
504
1.23
0.83
1.4
1.3
—
—
—
0
0
6
32
1.87
0.81
1.8
3.0
—
—
—
0
0
18
121
1.48
0.80
1.2
1.2
—
—
—
0
0
22
155
1.42
0.79
1.5
1.5
—
—
—
0
0
26
189
1.37
0.78
1.5
1.4
21.16
20.18
u/l
0.05
19
160
17
114
1.49
0.77
1.5
1.7
—
—
—
0
0
45
356
1.26
0.77
2.6
3.3
25.30
3711.74
u/ml
0.71
40
300
395
3680
1.09
0.76
1.4
1.5
0.92
2.70
u/ml
5.50
97
838
182
1630
1.12
0.76
1.6
1.6
—
—
—
0
0
135
1186
1.14
0.76
1.7
1.4
—
—
—
0
0
8
131
0.60
0.73
1.4
1.4
—
—
—
0
0
25
183
1.36
0.73
2.8
2.5
—
—
—
0
0
31
235
1.32
0.73
1.2
1.2
—
—
—
0
0
26
192
1.35
0.72
2.9
4.3
—
—
—
0
0
50
405
1.23
0.71
2.2
1.9
—
—
—
0
0
19
133
1.42
0.71
1.4
1.2
—
—
—
0
0
290
2674
1.10
0.71
3.5
3.3
524.69
275.72
mg/l
0.33
190
1768
527
4984
1.08
0.70
3.1
2.6
76.27
74.40
nmol/l
0.79
478
4566
7
41
1.70
0.69
2.7
2.5
—
—
—
0
0
9
58
1.54
0.69
1.2
1.1
1229.56
1499.43
miu/ml
—
9
58
280
2584
1.09
0.67
3.8
3.6
1.02
1.02
kg/l
0.12
36
389
92
795
1.16
0.67
1.3
1.2
15.15
48.10
au/ml
—
8
42
36
283
1.27
0.67
1.7
1.7
—
—
—
0
0
12
77
1.55
0.67
1.0
1.1
—
—
—
0
0
12
78
1.53
0.64
1.0
1.0
—
—
—
0
0
42
339
1.24
0.63
1.2
1.2
—
—
—
0
0
391
4101
0.93
0.62
2.5
2.5
—
—
—
0
0
29
224
1.29
0.62
3.1
3.5
1.10
1.45
e9/l
1.60
24
183
14
95
1.47
0.62
1.4
1.2
—
—
—
0
0
17
230
0.73
0.59
1.0
1.5
1.62
3.89
u/ml
0.80
11
153
15
105
1.42
0.58
1.3
1.7
—
—
—
0
0
12
80
1.49
0.58
2.2
2.2
—
—
—
0
0
11
72
1.52
0.57
1.0
1.2
—
—
—
0
0
10
64
1.56
0.57
1.0
1.2
—
—
—
0
0
6
36
1.66
0.56
1.2
1.6
—
—
—
0
0
5
86
0.58
0.56
1.0
1.1
—
1.32
nmol/l
—
0
19
41
337
1.21
0.55
1.3
1.2
—
—
—
0
0
9
60
1.49
0.54
4.3
3.5
80.24
135.17
ug/l
—
9
60
6
38
1.57
0.54
3.0
2.9
—
—
—
0
0
256
2383
1.08
0.52
3.9
4.2
1.62
2.13
ug/l
1.78
224
2169
6
39
1.53
0.52
1.3
1.2
—
—
—
0
0
145
1317
1.10
0.51
3.1
2.4
334.44
354.19
nmol/l
0.48
135
1240
64
552
1.16
0.51
2.9
2.8
0.07
0.17
e6/l
1.90
64
533
19
246
0.76
0.51
1.6
1.3
—
—
—
0
0
13
178
0.72
0.50
1.0
1.2
0.75
2.48
u/ml
—
8
105
7
45
1.55
0.48
2.3
2.3
—
—
—
0
0
10
67
1.49
0.48
2.8
2.7
51650.00
38632.91
ug/l
—
10
67
88
781
1.13
0.48
1.3
1.2
—
—
—
0
0
299
2811
1.07
0.48
4.1
3.9
11.43
8.32
mg/mmol
0.33
194
1824
70
787
0.88
0.47
1.8
1.9
—
—
—
0
0
25
198
1.26
0.47
1.5
1.4
—
—
—
0
0
20
154
1.29
0.46
2.5
4.2
10629.75
1907.17
u/ml
0.37
20
147
61
691
0.87
0.46
2.6
2.6
—
—
—
0
0
47
543
0.86
0.46
2.6
2.5
—
—
—
0
0
17
128
1.32
0.46
1.3
1.5
—
29.50
—
0
8
107
964
1.11
0.46
1.2
1.2
132.24
146.61
iu/ml
0.14
40
362
49
420
1.16
0.44
1.3
1.2
—
—
—
0
0
47
540
0.86
0.44
1.1
1.1
—
—
—
0
0
45
385
1.17
0.42
2.3
1.9
99.33
102.12
u/ml
—
9
42
24
193
1.24
0.41
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
0.09
—
0
9
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
33
1.51
0.41
1.2
1.2
—
—
—
0
0
358
3405
1.06
0.41
3.6
3.6
7.56
7.79
mmol/l
0.41
312
2977
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
5
34
1.46
0.40
2.6
2.0
—
—
—
0
0
5
36
1.38
0.38
1.4
1.3
—
—
—
0
0
8
112
0.71
0.37
1.4
1.2
—
—
—
0
0
99
902
1.10
0.36
2.3
2.2
11.09
11.67
nmol/l
0.27
89
808
23
188
1.22
0.35
1.5
1.7
3.54
5.03
mmol/24h
1.24
18
168
6
42
1.42
0.35
1.0
1.0
—
—
—
0
0
9
123
0.73
0.35
1.1
1.3
5.13
3.06
u/ml
—
9
116
12
155
0.77
0.34
1.5
1.7
—
—
—
0
0
24
198
1.21
0.34
3.2
3.6
0.31
0.20
e9/l
0.70
19
157
12
90
1.33
0.34
2.9
2.6
42.57
43.03
%
—
7
48
68
610
1.11
0.34
1.8
1.9
8.79
7.60
u/l
0.30
43
415
19
231
0.81
0.34
1.0
1.0
19.37
19.42
mmol/l
0.03
19
223
36
309
1.16
0.34
1.1
1.2
—
—
—
0
0
6
44
1.36
0.34
1.2
1.2
—
—
—
0
0
6
44
1.36
0.34
1.5
1.6
—
—
—
0
0
67
735
0.90
0.34
1.8
2.0
—
—
—
0
0
130
1205
1.08
0.33
1.3
1.3
—
—
—
0
0
98
898
1.09
0.33
1.9
1.5
—
—
—
0
0
6
46
1.30
0.33
1.3
2.4
14.73
18.58
umol/l
—
6
46
298
2844
1.05
0.31
1.9
1.9
—
—
—
0
0
23
271
0.84
0.31
1.2
1.1
1.83
4.43
u/ml
—
10
107
19
155
1.22
0.31
1.4
1.9
—
—
—
0
0
32
275
1.16
0.31
1.4
1.2
—
—
—
0
0
24
201
1.19
0.30
3.1
3.6
367.58
537.25
e6/l
1.62
19
157
19
227
0.83
0.30
1.0
1.0
-2.11
-2.17
mmol/l
—
8
48
19
227
0.83
0.30
1.0
1.0
—
—
—
0
0
110
1020
1.08
0.29
1.5
1.5
—
—
—
0
0
7
56
1.24
0.29
2.1
3.4
8.13
10.42
mg/l
—
7
48
30
258
1.16
0.29
1.4
1.4
84.32
126.14
pmol/l
0.45
30
252
10
75
1.33
0.29
1.1
1.2
—
—
—
0
0
73
787
0.92
0.28
1.8
2.0
—
—
—
0
0
75
807
0.92
0.27
1.4
1.4
—
—
—
0
0
8
64
1.24
0.27
1.5
2.3
—
—
—
0
0
10
76
1.31
0.27
1.2
2.4
—
—
—
0
0
24
204
1.17
0.27
1.1
1.1
—
—
—
0
0
74
795
0.92
0.26
1.9
2.0
—
—
—
0
0
20
168
1.18
0.25
1.4
1.8
—
1474.29
—
0
7
74
793
0.92
0.25
1.8
2.0
—
—
—
0
0
12
95
1.26
0.25
3.3
2.8
—
—
—
0
0
9
74
1.21
0.25
3.1
3.3
1256.44
989.19
u/ml
—
9
74
57
518
1.10
0.25
1.9
1.8
—
—
—
0
0
27
234
1.15
0.24
4.0
4.3
—
—
—
0
0
11
136
0.80
0.24
1.2
1.3
—
—
nmol/l
—
0
0
47
424
1.10
0.24
1.1
1.1
3.20
6.13
u/ml
—
6
73
103
966
1.06
0.22
4.8
3.7
—
—
—
0
0
239
2294
1.04
0.21
1.7
1.6
—
—
—
0
0
25
218
1.14
0.21
1.8
4.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
19
162
1.17
0.21
1.2
1.3
—
—
—
0
0
5
42
1.18
0.21
1.0
1.2
—
—
—
0
0
37
332
1.11
0.21
13.7
8.8
—
—
—
0
0
8
104
0.76
0.21
1.0
1.1
350.38
290.92
mg/l
—
8
95
11
133
0.82
0.20
1.3
1.2
—
—
—
0
0
18
207
0.86
0.20
4.6
3.1
1.84
1.49
mmol/l
0.61
18
200
0
14
0.00
0.20
0.0
5.9
—
—
—
0
0
140
1453
0.95
0.20
1.2
1.2
—
—
—
0
0
187
1927
0.96
0.20
2.0
2.8
107.03
109.67
ug/g
0.04
141
1558
6
50
1.19
0.19
4.3
2.4
513.17
512.22
min
—
6
37
16
136
1.17
0.19
6.8
4.1
23.75
26.23
umol/l
0.81
16
136
30
330
0.90
0.18
1.5
1.4
—
—
—
0
0
15
127
1.17
0.18
1.1
1.1
—
—
—
0
0
7
58
1.20
0.18
4.4
7.0
—
—
—
0
0
50
461
1.08
0.18
1.8
1.7
276.67
209.88
u/ml
0.82
36
237
35
380
0.91
0.17
2.3
2.4
—
—
—
0
0
23
203
1.13
0.17
1.0
1.1
12.78
8.51
iu/ml
—
6
31
30
328
0.91
0.17
1.5
1.4
—
—
—
0
0
31
337
0.91
0.16
1.5
1.5
—
—
—
0
0
10
82
1.21
0.16
1.2
1.4
78.10
74.59
umol/l
—
10
82
8
72
1.10
0.16
1.3
1.4
—
—
—
0
0
35
320
1.09
0.15
5.4
4.0
25.11
21.83
nmol/l
0.54
35
312
31
282
1.09
0.15
1.1
1.2
—
—
—
0
0
9
80
1.12
0.15
1.1
1.1
—
—
—
0
0
9
81
1.10
0.15
7.4
9.9
0.73
0.60
mmol/l
—
9
75
17
189
0.89
0.13
4.2
3.0
7.67
7.32
mmol/l
0.17
17
183
9
108
0.83
0.13
1.1
1.0
—
—
—
0
0
21
189
1.11
0.12
1.8
3.2
—
—
—
0
0
12
104
1.15
0.11
1.0
1.0
—
—
—
0
0
12
104
1.15
0.11
2.0
2.1
—
—
—
0
0
38
355
1.06
0.11
1.6
1.5
64.00
85.00
titre
—
5
34
207
2015
1.02
0.10
1.5
1.6
462.89
37113234.52
pmol/l
2.41
173
1711
19
206
0.91
0.10
1.8
1.6
—
—
—
0
0
13
115
1.12
0.09
3.6
2.4
—
—
—
0
0
6
55
1.08
0.08
1.2
1.4
—
—
—
0
0
22
203
1.08
0.08
1.1
1.1
—
—
—
0
0
14
153
0.91
0.08
1.0
1.3
3.51
24.08
u/ml
—
8
118
50
477
1.04
0.07
1.5
1.3
291.91
241.92
miu/ml
0.38
24
224
8
75
1.06
0.07
1.3
1.3
1.44
1.53
g/l
—
8
75
8
77
1.03
0.07
1.0
1.2
—
—
—
0
0
28
294
0.94
0.07
2.9
2.3
—
—
—
0
0
310
3113
0.99
0.06
3.5
3.1
—
—
—
0
0
10
89
1.12
0.06
3.8
2.6
73.70
53.42
umol/l
—
10
78
10
90
1.10
0.04
1.6
1.5
0.92
1.01
g/l
—
10
90
25
237
1.05
0.04
1.2
1.7
0.63
0.78
g/l
0.40
20
195
214
2107
1.01
0.03
1.7
1.7
—
—
—
0
0
13
138
0.94
0.03
1.2
1.3
—
—
—
0
0
62
628
0.98
0.03
1.9
2.0
—
—
—
0
0
21
218
0.96
0.03
2.1
1.9
—
4.80
—
0
5
43
437
0.98
0.02
1.7
1.7
—
—
—
0
0
12
127
0.94
0.02
1.0
1.1
—
—
—
0
0
10
92
1.08
0.02
1.0
1.1
—
—
—
0
0
27
260
1.03
0.02
1.1
1.1
—
—
—
0
0
143
1411
1.01
0.01
2.6
2.7
0.79
0.72
ug/l
0.21
88
833
78
767
1.01
0.01
1.7
1.6
—
—
—
0
0
67
673
0.99
0.01
1.8
1.6
—
—
—
0
0
22
212
1.03
0.01
2.4
2.3
126.25
131.27
ug/min
0.02
12
138
17
165
1.02
0.00
2.5
3.9
390.83
383.39
e6/l
0.02
12
112
13
131
0.99
0.00
1.1
1.3
—
—
—
0
0
15
150
0.99
0.00
1.3
1.3
0.68
0.56
nmol/l
0.68
15
142
17
166
1.02
0.00
1.3
1.5
—
—
—
0
0
51
509
0.99
0.00
2.9
3.2
—
—
—
0
0
78
772
1.00
0.00
1.8
1.7
23.30
21.63
iu/l
0.16
61
579
7
69
1.01
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
592.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
1520.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
177.86
—
0
7
6
67
0.89
-0.00
1.3
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
5
55
0.90
-0.00
1.0
1.3
121.60
143.33
nmol/l
—
5
55
8
81
0.98
-0.00
1.5
1.2
168.52
171.61
pmol/l
—
8
81
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
76
0.91
-0.00
1.1
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
6
59
1.01
-0.00
1.3
1.4
—
88.00
%
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
88
0.90
-0.00
2.3
1.8
119.38
124.88
ng/l
—
8
77
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
3.06
—
0
8

Mortality – FinRegistry

Association

Association between endpoint Q17_ASD and mortality.

Females

Parameter HR [95% CI] p-value
Q17_ASD 1.807 [1.57, 2.09] < 0.001
Birth year 0.999 [0.99, 1.01] 0.845

During the follow-up period (1.1.1998 — 31.12.2019), 451 out of 5990 females with Q17_ASD died.

Males

Parameter HR [95% CI] p-value
Q17_ASD 1.752 [1.5, 2.04] < 0.001
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 363 out of 4494 males with Q17_ASD died.

Mortality risk

Mortality risk for people of age

years, who have Q17_ASD.

N-year risk Females Males
1 0.2% 0.337%
5 1.099% 2.003%
10 2.988% 5.23%
15 5.839% 9.857%
20 10.621% 15.809%

Relationships between endpoints

Index endpoint: Q17_ASD – Atrial septal defect

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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