Benign neoplasm: Floor of mouth

CD2_BENIGN_FLOOROFMOUTH

oral cavity cancer: A primary or metastatic malignant neoplasm involving the oral cavity. The majority are squamous cell carcinomas.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D10.2& Hospital discharge: ICD-9 — 2103 Hospital discharge: ICD-8 — 2103 Cause of death: ICD-10 — D10.2& Cause of death: ICD-9 — 2103 Cause of death: ICD-8 — 2103 2 out of 7 registries used, show all original rules.	133
4. Check minimum number of events None	133
5. Include endpoints None	133
6. Filter based on genotype QC (FinnGen only)	128

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D10
Name in latin: Neoplasma benignum basis oris

NAME	CD2_BENIGN_FLOOROFMOUTH
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D102
HD_ICD_9	2103
HD_ICD_8	2103
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D102
COD_ICD_9	2103
COD_ICD_8	2103
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Floor of mouth based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1059	557	490
Only index persons	897	489	408
Unadjusted period prevalence (%)
Whole population	0.01	0.02	0.01
Only index persons	0.02	0.02	0.02
Median age at first event (years)
Whole population	53.91	54.65	52.78
Only index persons	51.89	53.01	50.55

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	128	69	59
Unadjusted period prevalence (%)	0.03	0.02	0.03
Median age at first event (years)	53.05	53.32	52.74

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
133: Matched controls
1330

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D10.2

ICD-10 Finland

Benign neoplasm: Floor of mouth

+∞

144.4

111

EJA10

NOMESCO Finland

Biopsy of tongue or floor of mouth

54.1

28.4

EJB30

NOMESCO Finland

Excision of tumor or other lesion of floor of the mouth

219.7

19.1

21030

ICD-8 Finland

Benign neoplasm of buccal cavity and pharynx, Floor of mouth

+∞

15.9

EP1CG

NOMESCO Finland

Extensive MRI examination of soft tissue of neck with high intesity magnet

84.6

7.5

PJD71

NOMESCO Finland

Extended sparing excision of cervical lymph nodes

84.6

7.5

EP1AE

NOMESCO Finland

Neck ultrasound examination

6.3

7.4

2103A

ICD-9 Finland

Benign neoplasm of lip, oral cavity and pharynx, Floor of mouth

+∞

7.4

ECA20

NOMESCO Finland

Biopsy of gingiva

31.9

7.2

WZC00

NOMESCO Finland

Treatment plan or consultation

2.7

7.1

304

EB1HA

NOMESCO Finland

Panorama tomography of teeth and jaws or similar X-ray examination

2.6

6.8

358

Z2221

NOMESCO Finland

Medical doctor

2.7

6.7

228

SAA03

NOMESCO Finland

Extended examination of mouth

2.5

6.3

358

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768804) Tissue Pathology biopsy report

414

2.53

6.47

2.6

2.0

—

(3006504) Eosinophils/100 leukocytes in Blood

502

2.13

4.39

4.8

6.1

2.42

2.73

0.65

473

(3019069) Monocytes/100 leukocytes in Blood

503

2.13

4.35

5.2

6.5

8.02

8.39

0.45

476

(40760892) CBC W Ordered Manual Differential panel - Blood

508

2.09

4.19

5.4

6.9

—

(3018010) Neutrophils/100 leukocytes in Blood

510

2.08

4.12

4.7

5.9

58.10

58.00

0.02

481

(3003458) Phosphate [Moles/volume] in Serum or Plasma

134

2.49

4.12

4.7

7.1

1.00

1.04

mmol/l

0.27

124

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

412

2.07

4.06

2.4

2.3

69.26

75.28

nmol/l

0.98

359

(3023368) Bacteria identified in Blood by Culture

287

2.12

3.98

4.9

4.5

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

2.84

3.93

1.7

2.8

0.21

0.22

g/l

0.14

(3002030) Lymphocytes/100 leukocytes in Blood

516

2.04

3.93

4.9

6.2

27.61

27.32

0.06

488

(3013115) Eosinophils [#/volume] in Blood

554

2.05

3.92

6.2

0.19

e9/l

0.04

503

(3001604) Monocytes [#/volume] in Blood

537

1.97

3.57

5.1

6.1

0.63

0.58

e9/l

0.70

482

(3006315) Basophils [#/volume] in Blood

538

1.96

3.54

5.1

6.1

0.04

e9/l

0.28

482

(3022096) Basophils/100 leukocytes in Blood

488

1.92

3.36

4.9

6.0

0.67

0.65

0.09

456

(3019198) Lymphocytes [#/volume] in Blood

550

1.89

3.20

5.1

6.1

2.17

1.79

e9/l

0.62

504

(3052851) Hemolysis interference index of Serum or Plasma

3.90

3.17

4.5

3.7

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

622

1.89

3.09

9.7

10.4

4.41

4.21

e9/l

0.32

557

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

4.12

2.83

1.0

1.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

229

1.92

2.73

2.6

2.2

—

(1002224) Polysomnography panel

2.97

2.72

1.1

—

(3042936) Bacteria identified in Isolate by Culture

147

2.05

2.57

2.1

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.46

2.53

1.4

1.7

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

171

1.97

2.52

3.0

3.6

59.05

175.64

ng/l

0.78

137

(3044889) 12 lead EKG panel

739

1.79

2.47

3.9

3.8

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

414

1.71

2.34

2.0

1.8

86.69

96.34

pmol/l

1.04

204

(40758558) Short blood count panel - Blood

275

1.77

2.29

8.0

6.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

730

1.72

2.21

4.6

4.3

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

220

1.80

2.18

1.7

1.05

1.23

mg/l

0.25

175

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

118

2.04

2.17

4.8

4.5

231.32

248.58

u/l

0.41

113

(3022217) INR in Platelet poor plasma by Coagulation assay

469

1.65

2.12

19.7

13.5

1.23

1.19

inr

0.12

143

(3021589) Normoblasts [#/volume] in Blood

471

1.64

2.08

8.5

10.2

0.00

e9/l

0.74

393

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

3.21

2.05

1.5

1.4

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

2.57

1.99

3.5

5.1

25.64

23.92

mmol/l

0.54

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

2.85

1.97

4.0

2.4

1.38

1.60

mg/l

—

(4035726) Immunohistochemistry procedure

2.12

1.95

1.8

1.3

—

(3044640) Blood type and Crossmatch panel - Blood

322

1.66

1.94

2.9

2.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

786

1.67

1.92

4.1

3.9

14.98

14.82

pmol/l

0.21

703

(3013826) Glucose [Moles/volume] in Serum or Plasma

623

1.61

1.91

6.5

4.5

6.34

6.65

mmol/l

0.91

569

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.33

1.91

2.4

2.2

146.82

231.28

ng/l

0.52

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.68

1.84

1.4

2.3

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.68

1.84

1.4

2.5

—

(3022145) Colonoscopy Study observation

103

1.99

1.83

1.6

1.4

—

(3000991) Gas panel - Venous blood

2.13

1.78

13.6

9.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

471

1.55

1.66

2.7

2.5

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

110

974

1.75

1.64

5.5

4.6

1.93

1.85

mu/l

0.26

101

875

(3000494) Fungus identified in Specimen by Culture

131

1.81

1.62

1.4

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

2.78

1.60

2.0

2.2

199.71

193.15

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.17

1.54

1.6

1.7

—

(3022948) Iron [Moles/volume] in Serum or Plasma

159

1.70

1.48

2.5

13.64

13.41

umol/l

0.05

145

(40761511) CBC panel - Blood by Automated count

122

1125

2.02

1.43

16.3

13.2

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

334

1.52

1.43

3.8

3.4

2.38

2.34

mmol/l

0.90

292

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.34

1.43

1.4

1.8

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.49

1.41

1.0

1.3

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.49

1.41

1.0

1.3

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.49

1.41

1.0

1.3

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.22

1.37

1.0

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

3.01

1.37

1.8

1.1

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

3.01

1.37

1.8

1.1

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

3.01

1.37

1.4

1.3

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.91

1.31

1.6

2.5

3.29

7.48

ug/l

2.03

(3009542) Hematocrit [Volume Fraction] of Blood

126

1187

2.17

1.30

29.2

20.8

40.22

40.65

0.45

118

1127

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.46

1.26

1.3

1.2

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

113

1029

1.65

1.25

4.2

4.5

6.17

5.92

mmol/l

0.91

936

(3019309) Folate [Moles/volume] in Red Blood Cells

201

1.57

1.24

1.6

1.7

911.18

1204.27

nmol/l

1.15

148

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

116

1064

1.71

1.24

19.9

14.1

24.26

21.67

mg/l

0.40

833

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

159

1.62

1.23

3.7

2.8

1.40

2.74

e6/l

—

(3018418) pH of Serum or Plasma

299

1.48

1.21

4.0

4.4

7.40

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

169

1.59

1.18

3.6

2.7

0.95

0.72

e6/l

0.24

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

111

1011

1.59

1.17

19.2

13.2

81.24

81.51

ml/min/173m2

0.04

808

(3007853) Bacteria identified in Skin by Aerobe culture

120

1.68

1.16

1.9

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

162

1.59

1.14

1.8

1.9

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

2.41

1.14

2.1

1.7

94.86

90.03

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

2.41

1.14

1.3

—

4.14

—

(3000492) Spirometry study

1.81

1.14

1.6

1.5

—

(3019225) pH of Specimen

1.77

1.13

3.5

5.4

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.94

1.11

1.4

1.2

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

2.43

1.10

3.6

2.8

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.72

1.09

2.2

2.6

47.25

32.38

u/l

0.63

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.12

1.04

2.4

—

(3009214) Lutropin [Units/volume] in Serum or Plasma

2.12

1.04

2.0

1.3

5.11

9.30

u/l

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

2.32

1.04

1.0

1.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.79

1.03

1.2

1.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.94

1.03

1.6

1.8

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

121

1134

1.74

1.02

11.2

10.3

28.83

26.91

u/l

0.31

116

1097

(1761868) Lipid panel - Serum or Plasma

429

0.69

1.02

3.0

2.9

—

(3018095) Leukocytes [#/volume] in Urine

384

1.39

1.00

5.3

3.7

63.99

59.19

e6/l

0.05

277

(3026782) Osmolality of Urine

220

1.47

0.99

3.9

2.9

460.40

564.61

mosm/kgh2o

2.17

186

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.99

0.0

2.0

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.99

0.0

1.3

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.79

0.96

4.0

4.9

128.33

83.82

ng/l

0.56

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

472

1.36

0.95

8.9

7.6

1.22

1.21

mmol/l

0.06

400

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.78

0.94

2.9

2.4

0.60

0.66

—

(3030467) Casts [#/volume] in Urine by Automated count

296

1.40

0.91

5.0

2.9

0.40

0.34

e6/l

0.12

219

(40768797) Stomach Pathology biopsy report

146

1.52

0.89

1.5

1.2

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

173

1.47

0.87

1.2

0.80

8.93

u/ml

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

374

1.35

0.85

4.7

3.2

—

(3002582) Erythrocytes [#/volume] in Urine

337

1.36

0.84

4.9

3.0

57.66

224.42

e6/l

0.42

263

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

426

0.73

0.82

3.5

4.0

—

(36304419) Bacteria [Presence] in Urine

293

1.36

0.80

4.9

2.8

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

124

1.52

0.80

16.0

7.3

102.94

104.37

mmol/l

0.56

124

(3011397) Hemoglobin [Presence] in Urine by Test strip

240

1.38

0.77

2.5

3.9

—

(3000850) Epithelial cells [#/volume] in Urine

231

1.39

0.77

4.2

2.6

5.57

4.52

e6/l

0.39

204

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.68

0.75

2.9

2.5

1.27

1.29

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

152

1.45

0.75

4.8

1.7

29.92

29.51

0.09

145

(3045414) Leukocytes [Presence] in Urine

1.89

0.75

1.1

1.6

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.59

0.71

22.3

5.1

25.26

24.94

mmol/l

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

1.96

0.71

1.2

1.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

311

0.72

0.70

3.8

3.5

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.88

0.69

1.0

1.7

—

(3049717) Cytology report of Urine Cyto stain

1.66

0.68

2.7

2.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

424

1.29

0.67

3.2

3.8

22.32

38.63

ng/l

1.03

288

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.82

0.67

1.0

1.6

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.82

0.67

1.0

1.2

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

104

1.50

0.66

3.8

1.9

387.20

350.86

nmol/l

0.48

(3002256) Pathology report gross observation

124

1.43

0.59

1.4

1.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

116

1.43

0.57

3.6

4.0

—

(3026008) Bacteria identified in Urine by Culture

317

1.28

0.57

3.6

3.1

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

1.61

0.55

1.7

2.0

37.33

40.58

nmol/l

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.51

0.52

1.5

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.52

0.52

1.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.41

0.52

1.7

2.3

—

(4200892) Spirometry reversibility

1.49

0.50

1.5

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

120

1.38

0.49

11.9

7.7

—

(3022621) pH of Urine by Test strip

1.51

0.48

2.6

2.5

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.52

0.48

1.9

3.6

23.60

24.16

mmol/l

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

104

983

1.27

0.48

5.2

5.6

41.09

40.02

mmol/mol

0.44

916

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

113

1079

1.31

0.48

4.7

2.76

mmol/l

0.01

102

992

(3012516) Albumin [Mass/volume] in Urine

287

1.25

0.47

3.5

3.1

2280.92

279.91

mg/l

0.42

185

(3001019) Free T4 and TSH panel - Serum or Plasma

1.42

0.46

2.6

1.9

—

(3013512) EKG study

308

1.23

0.44

4.5

3.7

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.48

0.44

1.0

1.3

—

(3019150) Specific gravity of Urine by Refractometry

237

0.77

0.44

3.0

4.2

1.02

kg/l

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.64

0.43

2.0

1.3

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

741

1.20

0.43

2.7

3.0

44.23

50.83

u/l

0.47

694

(3017143) Hepatitis C virus Ab [Presence] in Serum

132

1.33

0.43

1.5

1.6

—

(36660697) Celiac disease serology panel - Serum

1.43

0.42

1.4

1.1

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.41

0.0

1.1

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.41

0.0

3.1

—

56.53

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.41

0.0

1.2

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.41

0.0

1.6

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

116

1.33

0.39

1.9

1.6

—

(3026493) Urate [Moles/volume] in Serum or Plasma

293

1.22

0.39

3.5

2.9

351.29

8385.00

umol/l

1.50

250

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

154

1.27

0.36

1.3

1.4

—

(3029937) Albumin [Presence] in Urine by Test strip

305

0.82

0.36

3.2

4.1

0.00

estimate

-0.00

110

(3008898) HLA-B27 [Presence]

1.45

0.36

1.2

1.1

—

(3013707) Erythrocyte sedimentation rate by Westergren method

799

1.18

0.35

4.3

4.1

11.95

11.75

mm/h

0.06

727

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

127

1.30

0.35

4.9

4.3

26.10

30.10

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

1.37

0.35

2.9

3.5

72.67

64.26

ml/min/173m2

—

(3020891) Body temperature

1.38

0.35

4.2

4.7

—

(3000330) Specific gravity of Urine by Test strip

1.38

0.35

2.8

4.3

—

(3020682) Albumin/Creatinine [Ratio] in Urine

307

1.19

0.33

4.3

3.7

13.32

8.80

mg/mmol

0.34

197

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.32

0.33

1.3

2.1

44.78

42.60

u/l

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

1.32

0.33

1.3

2.1

1.44

1.56

g/l

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

360

1.16

0.28

5.0

4.5

2.18

1.95

ug/l

0.23

321

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.27

0.28

1.3

1.2

—

33.90

—

(40761535) Cells panel - Urine sediment

1.27

0.26

1.9

3.8

—

(3019060) Gas panel - Arterial blood

1.23

0.26

4.3

4.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

709

1.13

0.25

2.8

3.0

—

(3003694) ABO and Rh group [Type] in Blood

267

1.16

0.24

1.4

1.5

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

109

1059

1.16

0.22

4.1

4.3

4.69

4.67

mmol/l

0.09

980

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

117

1.22

0.21

2.1

1.7

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.21

0.0

2.2

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.21

0.0

3.1

—

13.61

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

0.21

0.0

1.7

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.21

0.0

4.3

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3051014) Leukocytes [#/area] in Urine sediment by Automated count

0.00

0.21

0.0

1.8

—

0.20

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.21

0.0

1.0

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.21

0.0

1.5

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.21

0.0

1.2

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

193

1.17

0.21

1.3

1.5

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

108

1.23

0.21

1.4

1.9

—

(3019977) pH of Arterial blood

0.00

0.21

0.0

8.0

—

7.44

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.26

0.20

1.8

3.1

49.30

53.28

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.21

0.20

2.3

2.7

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.16

0.19

18.3

7.3

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.24

0.17

2.7

5.2

1.23

1.21

mmol/l

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.12

0.15

1.8

2.4

11.33

10.08

g/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

199

1.13

0.14

1.5

1.4

2.55

2.66

g/l

0.08

125

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

106

0.84

0.13

1.6

1.9

—

(3009261) Glucose [Presence] in Urine by Test strip

545

0.92

0.13

3.4

3.9

0.00

estimate

-0.00

111

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

104

1018

1.10

0.13

3.8

3.9

1.44

1.31

mmol/l

0.82

926

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

220

1.11

0.13

3.4

2.7

0.74

0.73

ug/l

0.03

142

(46235355) HIV 1 and 2 tests - Meaningful Use set

203

1.10

0.10

1.6

1.8

—

(40768443) Skin Pathology biopsy report

1.07

0.09

1.6

1.2

—

(3021601) Nitrite [Presence] in Urine by Test strip

540

0.94

0.09

4.9

5.3

0.00

estimate

-0.00

114

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

124

0.88

0.09

2.3

1.6

1.46

1.41

0.17

106

(3028026) IgM [Mass/volume] in Serum or Plasma

1.05

0.08

1.3

1.7

0.79

1.17

g/l

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

305

0.94

0.07

1.4

1.6

1.58

1.46

mmol/l

0.25

258

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

167

1.09

0.07

1.6

—

(40761536) Microorganisms panel - Urine sediment

101

0.88

0.06

5.7

3.9

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

296

1.06

0.06

4.7

4.2

23.98

22.07

0.35

137

(21494755) Public health laboratory ask at order entry panel

108

0.92

0.03

1.1

1.4

—

(3019832) Treponema pallidum Ab [Presence] in Serum

108

0.92

0.03

2.0

1.8

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

117

0.93

0.02

1.5

2.1

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

105

1054

0.98

0.00

4.3

1.41

1.45

mmol/l

0.48

966

(3035350) Ketones [Presence] in Urine by Test strip

535

0.98

0.00

3.3

3.9

0.00

0.01

estimate

0.50

117

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.02

0.00

1.0

1.5

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

108

1.02

0.00

1.9

1.7

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.1

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

-0.00

0.0

9.8

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.5

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3020013) Alkaline phosphatase.intestinal [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

11.30

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.1

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

11.00

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.1

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.3

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

9.6

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

9.5

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

0.86

-0.00

9.0

7.7

25.97

24.93

mmol/l

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3002079) Sodium [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.0

—

166.73

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

2.6

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.2

—

6.53

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.1

—

(3014891) Appearance of Pleural fluid

0.00

-0.00

0.0

1.2

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3015076) Soybean IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.3

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

0.95

-0.00

1.3

1.2

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.1

—

2.91

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

71.98

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

-0.00

0.0

1.5

—

17.00

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_FLOOROFMOUTH and mortality.

Females

Parameter	HR [95% CI]	p-value
CD2_BENIGN_FLOOROFMOUTH	1.587 [1.24, 2.04]	< 0.001
Birth year	0.996 [0.99, 1.01]	0.416

During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 431 females with CD2_BENIGN_FLOOROFMOUTH died.

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_FLOOROFMOUTH	1.841 [1.37, 2.48]	< 0.001
Birth year	0.991 [0.98, 1.0]	0.045

During the follow-up period (1.1.1998 — 31.12.2019), 106 out of 342 males with CD2_BENIGN_FLOOROFMOUTH died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_FLOOROFMOUTH.

N-year risk	Females	Males
1	0.164%	0.368%
5	0.817%	2.139%
10	2.325%	5.75%
15	4.773%	10.59%
20	8.665%	17.4%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_FLOOROFMOUTH – Benign neoplasm: Floor of mouth

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Floor of mouth

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints