Benign neoplasm: Floor of mouth

CD2_BENIGN_FLOOROFMOUTH

oral cavity cancer: A primary or metastatic malignant neoplasm involving the oral cavity. The majority are squamous cell carcinomas.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D10.2&
  • Hospital discharge: ICD-9 2103
  • Hospital discharge: ICD-8 2103
  • Cause of death: ICD-10 D10.2&
  • Cause of death: ICD-9 2103
  • Cause of death: ICD-8 2103

2 out of 7 registries used, show all original rules.

129

4. Check minimum number of events

None

129

5. Include endpoints

None

129

6. Filter based on genotype QC (FinnGen only)

129

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum basis oris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1059 557 490
Only index persons 897 489 408
Unadjusted period prevalence (%)
Whole population 0.01 0.02 0.01
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 53.91 54.65 52.78
Only index persons 51.89 53.01 50.55

-FinnGen-

Key figures

All Female Male
Number of individuals 129 70 59
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 51.62 50.68 52.74

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
115
Matched controls
1150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.2
ICD-10 Finland
Benign neoplasm: Floor of mouth
+∞
124.7
96
*
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
66.7
26.8
30
6
EJB30
NOMESCO Finland
Excision of lesion of floor of mouth
183.7
15.9
16
*
21030
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Floor of mouth
+∞
14.9
14
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
85.2
7.5
8
*
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(40768804) Tissue Pathology biopsy report
70
404
2.60
6.63
2.6
2.0
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
74
487
2.22
4.67
4.7
6.1
%
2.4
2.7
0.70
65
457
(42870588) Differential panel, method unspecified - Blood
57
338
2.23
4.66
3.9
5.7
—
—
—
0
0
(3019069) Monocytes/100 leukocytes in Blood
74
488
2.21
4.63
5.0
6.4
%
8.0
8.4
0.49
67
461
(3018010) Neutrophils/100 leukocytes in Blood
74
494
2.17
4.42
4.6
5.9
%
58.3
58.0
0.05
68
464
(3002030) Lymphocytes/100 leukocytes in Blood
74
500
2.13
4.22
4.7
6.2
%
27.4
27.2
0.04
68
468
(3013115) Eosinophils [#/volume] in Blood
77
536
2.08
3.97
6.1
6.3
e9/l
0.2
0.2
0.00
66
485
(3003458) Phosphate [Moles/volume] in Serum or Plasma
28
131
2.45
3.87
4.9
7.0
mmol/l
1.0
1.0
0.31
23
121
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
62
405
2.02
3.74
2.4
2.3
nmol/l
69.7
75.2
0.84
56
353
(3052851) Hemolysis interference index of Serum or Plasma
11
30
3.92
3.72
4.6
3.9
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
74
518
2.01
3.64
4.9
6.1
e9/l
0.6
0.6
0.63
63
463
(3006315) Basophils [#/volume] in Blood
74
520
1.99
3.58
5.0
6.2
e9/l
0.0
0.0
0.36
63
464
(3022096) Basophils/100 leukocytes in Blood
69
474
1.98
3.56
4.8
6.0
%
0.7
0.6
0.14
62
442
(3023368) Bacteria identified in Blood by Culture
46
280
2.00
3.30
5.1
4.6
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
74
530
1.93
3.29
4.9
6.1
e9/l
2.2
1.8
0.55
64
482
(3013650) Neutrophils [#/volume] in Blood by Automated count
81
603
1.92
3.15
9.3
10.3
e9/l
4.4
4.2
0.34
68
538
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
9
23
4.12
2.83
1.0
1.2
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
30
167
2.04
2.71
3.0
3.7
ng/l
59.0
179.5
0.80
22
134
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
37
224
1.91
2.63
2.5
2.2
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
57
406
1.72
2.34
2.0
1.9
pmol/l
86.7
96.6
1.07
34
197
(1002224) Polysomnography panel
11
41
2.84
2.34
1.1
1.1
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
35
216
1.85
2.33
1.7
1.7
mg/l
1.1
1.2
0.26
22
173
(3037467) Urinalysis macro (dipstick) panel - Urine
87
709
1.70
2.07
4.7
4.3
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
8
26
3.21
2.05
1.5
1.4
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
109
949
1.96
2.05
20.9
14.3
%
41.1
40.6
0.34
73
713
(3030366) Cystatin C [Mass/volume] in Serum or Plasma
9
32
2.94
2.04
4.0
2.3
mg/l
1.4
1.6
—
9
27
(40758558) Short blood count panel - Blood
40
267
1.72
2.03
7.4
6.6
—
—
—
0
0
(3044889) 12 lead EKG panel
88
722
1.69
2.01
3.9
3.8
—
—
—
0
0
(4035726)
17
85
2.15
2.01
1.8
1.3
—
—
—
0
0
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
11
45
2.58
1.99
3.5
5.1
mmol/l
25.6
24.0
0.52
11
39
(3044640) Blood type and Crossmatch panel - Blood
45
314
1.67
1.93
2.9
2.2
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
21
117
1.95
1.88
4.7
4.4
u/l
230.8
248.5
0.40
21
112
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
9
35
2.69
1.84
1.4
2.3
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
9
35
2.69
1.84
1.4
1.7
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
9
35
2.69
1.84
1.4
2.5
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
14
68
2.19
1.78
1.3
1.7
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
24
144
1.82
1.73
2.1
1.7
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
60
460
1.57
1.72
8.6
10.3
e9/l
0.0
0.0
0.74
45
383
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
10
43
2.44
1.65
1.0
1.0
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
53
399
1.56
1.62
8.5
8.2
inr
1.2
1.2
0.02
19
130
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
90
763
1.59
1.62
4.0
3.9
pmol/l
15.0
14.8
0.27
83
681
(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay
7
26
2.79
1.60
2.0
2.2
%
199.7
193.2
—
7
26
(3022145) Colonoscopy Study observation
18
101
1.91
1.58
1.6
1.4
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
12
58
2.18
1.55
1.6
1.7
—
—
—
0
0
(3012544) pH of Venous blood
16
88
1.93
1.49
3.1
4.7
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
12
59
2.14
1.49
2.5
2.2
ng/l
157.1
231.3
0.42
12
51
(3022948) Iron [Moles/volume] in Serum or Plasma
25
159
1.71
1.49
2.5
2.5
umol/l
13.6
13.4
0.04
25
143
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
7
28
2.58
1.47
1.0
1.3
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
7
28
2.58
1.47
1.0
1.3
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
7
28
2.58
1.47
1.0
1.3
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
106
944
1.69
1.46
5.4
4.6
mu/l
1.9
1.9
0.25
97
847
(3013826) Glucose [Moles/volume] in Serum or Plasma
74
609
1.50
1.46
6.5
4.5
mmol/l
6.4
6.7
0.84
68
556
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
5
16
3.21
1.45
1.8
1.1
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
5
16
3.21
1.45
1.8
1.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
58
457
1.49
1.40
3.9
4.1
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
118
1088
1.99
1.38
16.3
13.4
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
5
17
3.02
1.37
1.4
1.3
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
14
76
1.94
1.36
1.6
2.5
ug/l
3.3
7.5
1.98
14
67
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
9
43
2.17
1.33
1.9
1.7
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
110
997
1.70
1.32
4.2
4.5
mmol/l
6.2
5.9
1.03
96
906
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
6
25
2.47
1.26
1.3
1.2
—
—
—
0
0
(3019225) pH of Specimen
15
86
1.84
1.25
3.5
5.4
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
20
126
1.70
1.23
1.4
1.4
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
24
159
1.63
1.23
1.8
1.9
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
43
327
1.47
1.21
3.8
3.4
mmol/l
2.4
2.3
0.91
36
284
(3000991) Gas panel - Venous blood
13
73
1.87
1.15
15.3
9.4
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
112
1029
1.67
1.15
19.9
14.4
mg/l
24.6
21.5
0.48
95
807
(3019309) Folate [Moles/volume] in Red Blood Cells
28
196
1.55
1.15
1.6
1.7
nmol/l
825.0
1210.0
2.09
20
145
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
7
30
2.41
1.14
2.1
1.7
%
94.9
90.0
—
7
30
(3009214) Lutropin [Units/volume] in Serum or Plasma
7
30
2.41
1.14
2.0
1.3
u/l
5.1
9.6
—
7
24
(3016921) Smith extractable nuclear Ab [Units/volume] in Serum
7
30
2.41
1.14
1.3
1.3
—
4.1
—
0
5
(3013139) Helicobacter pylori Ag [Presence] in Stool
11
59
1.94
1.11
1.4
1.2
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
5
21
2.43
1.10
3.6
2.8
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
12
67
1.87
1.09
4.0
5.0
ng/l
128.3
86.0
0.52
12
60
(3026782) Osmolality of Urine
30
217
1.50
1.06
3.9
2.7
mosm/kgh2o
460.4
573.4
2.45
30
183
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
23
157
1.57
1.05
3.7
2.8
e6/l
1.4
2.7
—
10
89
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
5
22
2.32
1.04
1.0
1.6
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
24
166
1.55
1.04
3.7
2.7
e6/l
0.9
0.7
0.22
11
96
(3007853) Bacteria identified in Skin by Aerobe culture
18
116
1.64
1.03
2.0
1.6
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
28
0.00
0.99
0.0
1.3
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
28
0.00
0.99
0.0
2.0
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
47
377
1.39
0.96
5.4
3.7
e6/l
64.0
60.0
0.04
38
273
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
107
985
1.51
0.95
18.9
13.4
ml/min/173m2
79.8
81.1
0.24
89
785
(40768797) Stomach Pathology biopsy report
21
145
1.54
0.92
1.5
1.2
—
—
—
0
0
(3018418) pH of Serum or Plasma
38
296
1.40
0.92
4.1
4.4
ph
7.4
7.4
—
9
57
(3000492) Spirometry study
13
79
1.72
0.92
1.6
1.5
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
117
1100
1.68
0.92
11.1
10.4
u/l
29.0
26.5
0.43
112
1064
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
15
96
1.64
0.89
2.2
2.6
u/l
46.7
32.5
0.54
15
78
(1761868) Lipid panel - Serum or Plasma
33
418
0.72
0.86
3.0
2.9
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
32
245
1.41
0.85
5.1
6.1
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
12
73
1.71
0.85
1.2
1.5
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
37
292
1.37
0.83
5.1
2.9
e6/l
0.4
0.3
0.11
31
215
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
33
415
0.72
0.82
3.6
4.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
45
367
1.35
0.82
4.8
3.2
—
—
—
0
0
(3000850) Epithelial cells [#/volume] in Urine
30
229
1.40
0.81
4.2
2.6
e6/l
5.6
4.6
0.34
30
200
(3020564) Creatinine [Moles/volume] in Serum or Plasma
116
1096
1.58
0.78
22.6
16.4
umol/l
78.6
79.4
0.12
116
1096
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
23
168
1.45
0.78
1.2
1.2
u/ml
0.8
6.4
—
5
76
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
6
34
1.80
0.77
2.7
2.4
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
41
333
1.34
0.76
4.9
3.0
e6/l
57.7
227.8
0.42
34
259
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
5
25
2.04
0.73
1.2
1.6
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
36
289
1.34
0.72
5.0
2.8
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
38
308
1.33
0.71
3.5
3.1
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
5
27
1.89
0.69
1.0
1.7
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
28
1.82
0.67
1.0
1.2
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
5
28
1.82
0.67
1.0
1.6
—
—
—
0
0
(3002256) Pathology report gross observation
17
121
1.47
0.66
1.4
1.2
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
111
1048
1.42
0.66
4.8
4.8
mmol/l
2.8
2.7
0.02
100
961
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
49
418
1.28
0.63
3.2
3.8
ng/l
22.8
38.7
0.98
35
287
(3041096) Erythrocytes [Presence] in Urine by Automated
24
305
0.74
0.63
3.8
3.5
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
5
30
1.69
0.62
2.0
1.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
29
231
1.33
0.61
2.5
3.9
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
20
150
1.39
0.60
4.9
1.8
s
30.2
29.5
0.15
20
143
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
16
115
1.45
0.60
3.6
4.0
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
8
53
1.54
0.59
2.8
2.5
%
0.9
1.3
—
8
53
(3004716) Salmonella sp identified in Stool by Organism specific culture
8
54
1.51
0.58
1.0
1.3
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
11
73
1.55
0.58
1.5
1.5
—
—
—
0
0
(4010399)
11
73
1.55
0.58
1.5
1.4
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
6
36
1.70
0.57
1.7
1.8
nmol/l
37.3
40.9
—
6
36
(3012516) Albumin [Mass/volume] in Urine
34
280
1.29
0.57
3.5
3.1
mg/l
2280.9
289.1
0.41
21
176
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
53
463
1.25
0.55
9.3
7.7
mmol/l
1.2
1.2
0.24
47
389
(3013512) EKG study
36
302
1.27
0.52
4.5
3.7
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
6
40
1.52
0.52
1.2
1.2
—
—
—
0
0
(3008898) HLA-B27 [Presence]
6
40
1.52
0.52
1.2
1.1
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
14
101
1.43
0.52
3.6
1.9
nmol/l
387.4
351.1
0.44
14
88
(3004588) Protein electrophoresis panel - Serum or Plasma
9
65
1.41
0.52
1.7
2.3
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
18
231
0.74
0.50
3.1
4.2
kg/l
1.0
1.0
—
5
24
(3029937) Albumin [Presence] in Urine by Test strip
24
295
0.77
0.50
3.4
4.2
estimate
0.0
0.0
—
10
107
(3026493) Urate [Moles/volume] in Serum or Plasma
34
286
1.26
0.48
3.5
2.9
umol/l
351.3
8652.8
1.50
28
242
(3001019) Free T4 and TSH panel - Serum or Plasma
7
50
1.42
0.46
2.6
1.9
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
15
113
1.37
0.45
1.9
1.6
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
16
123
1.34
0.43
4.9
4.3
%
26.1
30.4
—
10
75
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
8
58
1.40
0.42
25.0
5.1
mmol/l
24.8
24.9
—
8
58
(3020682) Albumin/Creatinine [Ratio] in Urine
35
300
1.23
0.42
4.3
3.9
mg/mmol
13.3
8.6
0.36
23
190
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
101
959
1.25
0.42
5.4
5.7
mmol/mol
41.3
40.1
0.48
93
892
(3023511) Choriogonadotropin [Units/volume] in Urine
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
16
0.00
0.41
0.0
3.2
—
58.8
—
0
16
(3017143) Hepatitis C virus Ab [Presence] in Serum
16
124
1.33
0.41
1.5
1.5
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
(3022621) pH of Urine by Test strip
9
66
1.39
0.39
2.8
2.5
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
5
36
1.40
0.38
1.2
1.5
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
6
41
1.49
0.36
3.0
2.3
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
77
719
1.18
0.36
2.7
3.0
u/l
45.3
51.4
0.40
70
673
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
107
1028
1.24
0.35
4.1
4.4
mmol/l
4.7
4.7
0.14
97
950
(3027273) Bicarbonate [Moles/volume] in Venous blood
6
45
1.35
0.34
1.5
3.6
mmol/l
23.3
24.3
—
6
45
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
6
46
1.32
0.33
1.3
2.1
u/l
44.8
42.6
—
6
41
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
6
46
1.32
0.33
1.3
2.1
g/l
1.4
1.6
—
6
36
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
18
147
1.26
0.33
1.3
1.3
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
40
358
1.17
0.31
5.0
4.5
ug/l
2.2
2.0
0.23
33
319
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
8
64
1.27
0.28
1.3
1.2
—
33.9
—
0
5
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
72
677
1.14
0.28
2.8
3.0
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
13
104
1.28
0.27
1.4
1.9
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
21
179
1.21
0.27
1.3
1.5
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
10
77
1.32
0.27
1.4
1.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
14
114
1.26
0.26
2.1
1.7
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
14
115
1.24
0.24
12.2
7.8
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
102
988
1.15
0.22
3.9
3.9
mmol/l
1.4
1.3
0.90
88
897
(4268621)
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
10
0.00
0.21
0.0
4.7
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3051014) Leukocytes [#/area] in Urine sediment by Automated count
0
10
0.00
0.21
0.0
1.8
—
0.2
—
0
5
(4281824)
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
(3019977) pH of Arterial blood
0
13
0.00
0.21
0.0
8.0
—
7.4
—
0
5
(3021601) Nitrite [Presence] in Urine by Test strip
49
524
0.90
0.20
5.1
5.3
estimate
0.0
0.0
0.00
11
111
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
6
50
1.21
0.20
2.3
2.7
—
—
—
0
0
(3015736) pH of Urine
44
410
1.11
0.18
2.6
3.7
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
81
779
1.11
0.18
4.1
4.1
mm/h
11.9
11.9
0.02
75
709
(40761535) Cells panel - Urine sediment
8
69
1.17
0.17
2.0
3.7
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
50
529
0.91
0.16
3.4
3.9
estimate
0.0
0.0
0.00
11
108
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
9
82
1.10
0.15
2.8
5.2
mmol/l
1.2
1.2
—
9
71
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
24
218
1.12
0.15
3.4
2.7
ug/l
0.7
0.7
0.02
16
141
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
8
99
0.80
0.14
1.6
1.9
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
21
190
1.13
0.14
1.6
1.8
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
5
43
1.17
0.10
3.2
4.3
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
5
46
1.09
0.09
1.4
3.2
%
51.1
52.5
—
5
46
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
17
155
1.11
0.09
1.6
1.6
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
21
195
1.09
0.08
1.4
1.5
g/l
2.7
2.7
0.02
11
121
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
5
63
0.79
0.08
1.4
1.2
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
50
518
0.94
0.08
3.4
3.9
estimate
0.0
0.0
0.00
11
109
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
31
294
1.07
0.08
4.7
4.2
%
24.0
22.1
0.33
12
136
(3003694) ABO and Rh group [Type] in Blood
27
255
1.07
0.07
1.4
1.5
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
8
93
0.85
0.07
24.4
8.6
g/l
107.9
120.7
—
8
88
(21494755) Public health laboratory ask at order entry panel
9
103
0.86
0.06
1.1
1.4
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
10
110
0.90
0.05
1.5
2.1
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
11
119
0.92
0.04
2.3
1.6
%
1.5
1.4
0.21
11
102
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
29
298
0.97
0.02
1.4
1.6
mmol/l
1.6
1.5
0.25
24
251
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
11
103
1.07
0.02
1.9
1.7
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
103
1023
1.03
0.01
4.3
4.3
mmol/l
1.4
1.5
0.59
91
935
(3019832) Treponema pallidum Ab [Presence] in Serum
10
96
1.05
0.00
2.0
1.7
—
—
—
0
0
(3019060) Gas panel - Arterial blood
7
73
0.96
0.00
4.9
4.2
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(4211845)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
8
0.00
0.00
0.0
9.6
—
—
—
0
0
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
11.0
—
0
5
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum
0
6
0.00
0.00
0.0
1.5
—
17.0
—
0
6
(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
9
0.00
0.00
0.0
2.9
—
13.7
—
0
9
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
5
0.00
0.00
0.0
1.2
—
6.5
—
0
5
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
4.1
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
8
80
1.00
0.00
1.9
2.5
g/l
11.7
10.1
—
8
71
(3035933) Granulocytes/100 leukocytes in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
6
66
0.90
0.00
1.3
1.7
g/l
0.8
1.2
—
6
59
(40761536) Microorganisms panel - Urine sediment
9
98
0.91
0.00
5.7
3.9
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
8
0.00
0.00
0.0
4.1
—
—
—
0
0
(3026470) Cobalt [Mass/volume] in Blood
0
7
0.00
0.00
0.0
2.1
—
2.9
—
0
7
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
72.0
—
0
5
(3015076) Soybean IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
9
90
1.00
0.00
1.0
1.5
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028679) Herpes simplex virus Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017569) Oxygen content in Arterial blood
0
8
0.00
0.00
0.0
9.5
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014891) Appearance of Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3020876) Protein [Mass/time] in 24 hour Urine
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
52
0.96
0.00
21.8
7.3
—
—
—
0
0
(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate
0
5
0.00
0.00
0.0
10.0
—
—
—
0
0
(21491868) Cryoglobulin [Mass/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3036071) Salmonella sp Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_FLOOROFMOUTH and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_FLOOROFMOUTH 1.587 [1.24, 2.04] < 0.001
Birth year 0.996 [0.99, 1.01] 0.416

During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 431 females with CD2_BENIGN_FLOOROFMOUTH died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_FLOOROFMOUTH 1.841 [1.37, 2.48] < 0.001
Birth year 0.991 [0.98, 1.0] 0.045

During the follow-up period (1.1.1998 — 31.12.2019), 106 out of 342 males with CD2_BENIGN_FLOOROFMOUTH died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_FLOOROFMOUTH.

N-year risk Females Males
1 0.164% 0.368%
5 0.817% 2.139%
10 2.325% 5.75%
15 4.773% 10.59%
20 8.665% 17.4%

Relationships between endpoints

Index endpoint: CD2_BENIGN_FLOOROFMOUTH – Benign neoplasm: Floor of mouth

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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