endocrine system disease: A disease involving the endocrine system.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2051 |
4. Check minimum number of eventsNone |
2051 |
5. Include endpoints |
2167 |
6. Filter based on genotype QC (FinnGen only) |
2167 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other endocrine disorders
based on the number of shared cases.
Similar with more cases:
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 31129 | 16403 | 14689 |
| Only index persons | 22605 | 12208 | 10397 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.44 | 0.47 | 0.41 |
| Only index persons | 0.42 | 0.45 | 0.40 |
| Median age at first event (years) | |||
| Whole population | 7.81 | 8.09 | 7.35 |
| Only index persons | 10.77 | 11.10 | 10.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2167 | 1294 | 873 |
| Unadjusted period prevalence (%) | 0.42 | 0.44 | 0.38 |
| Median age at first event (years) | 15.85 | 15.95 | 15.70 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1937
- Matched controls
- 18807
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E34.35
ICD-10 Finland
Abnormal growth retardation
1301.2
323.0
421
*
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
+∞
323.0
558
*
E34.0
ICD-10 Finland
Carcinoid syndrome
+∞
291.2
275
*
H01AC01
ATC
somatropin; parenteral
1448.0
269.3
259
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
930.0
258.8
251
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
21.1
217.5
334
184
E34.30
ICD-10 Finland
Short stature NOS
+∞
206.9
197
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
189.8
181
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
137.7
132
*
H01CB02
ATC
octreotide; parenteral
170.3
124.5
131
8
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
+∞
110.3
106
*
E34.40
ICD-10 Finland
Constitutional tall stature
+∞
108.2
104
*
301
Kela drug reimbursment
Growth hormone
530.7
104.5
104
*
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
97.9
102.9
114
12
H01CB03
ATC
lanreotide; parenteral
195.9
92.1
96
5
E34.45
ICD-10 Finland
Abnormal growth increase
428.6
84.8
85
*
E34.31
ICD-10 Finland
Short stature, prenatal disorder
829.0
83.2
82
*
130
Kela drug reimbursment
Malignant tumour
6.1
82.0
241
428
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
49.8
76.2
93
19
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
259.5
75.1
77
*
H02AB09
ATC
hydrocortisone; systemic
7.4
69.6
175
249
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
224.3
64.8
67
*
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
63.0
64.0
75
12
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
14.1
57.8
101
73
25898
ICD-8 Finland
Polyglandular dysfunction and other diseases of endocrine glands, Alii definiti
+∞
56.9
55
*
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
18.1
56.2
89
50
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
+∞
55.9
54
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.8
55.4
197
431
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
+∞
54.8
53
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
8.1
54.3
127
161
H03AA01
ATC
levothyroxine sodium; systemic
2.6
53.2
451
1936
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
52.8
51
*
C17.2
ICD-10 Finland
Malignant neoplasm: Ileum
111.9
51.4
56
5
JN4CD
NOMESCO Finland
Very extensive body CT
8.5
50.4
114
137
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
50.0
49.4
60
12
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.8
48.2
170
367
25899
ICD-8 Finland
Polyglandular dysfunction and other diseases of endocrine glands, Other and unspecified diseases of endocrine system
+∞
47.6
46
*
8240/3-C17.9
ICD-O-3
Neuroendocrine tumor, NOS, of small intestine, NOS
238.6
46.6
48
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
46.5
626
3360
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
101.6
46.4
51
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
45.3
767
4534
JFB00
NOMESCO Finland
Partial resection of small intestine
11.0
44.6
87
80
E34.3
ICD-10 Finland
Short stature, not elsewhere classified
+∞
44.5
43
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
42.4
230
729
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
5.7
41.9
125
223
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
41.0
375
1652
E34.8
ICD-10 Finland
Other specified endocrine disorders
+∞
39.3
38
*
JN4BD
NOMESCO Finland
Extensive body CT
3.3
38.7
210
664
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
38.1
499
2604
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
38.1
411
1962
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
7.2
37.6
94
132
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
35.8
195
617
E30.00
ICD-10 Finland
Familial delayed puberty
353.1
35.7
36
*
E30.09
ICD-10 Finland
Delayed puberty NOS
353.1
35.7
36
*
D77
ICPC
Malignant digestive neopl other/NOS
39.7
34.9
44
11
JN4AD
NOMESCO Finland
Body CT examination
3.8
34.2
153
413
Z31.5
ICD-10 Finland
Genetic counselling
3.3
34.2
182
566
L01AX03
ATC
temozolomide; systemic
27.5
34.2
47
17
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
23.2
34.0
49
21
XX3DW
NOMESCO Finland
Time consuming IT work
3.0
32.3
199
685
SPAT1262
SPAT
Handing over of treatment supplies
2.4
31.3
308
1391
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.4
31.2
161
488
JN7AN
NOMESCO Finland
Somatostatin receptor isotope imaging
+∞
31.0
30
*
602
Kela drug reimbursment
Children's severe malnutrition
5.8
30.6
89
154
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
16.8
30.5
49
29
302
Kela drug reimbursment
Interferon alfa
157.8
30.4
32
*
UJF32
NOMESCO Finland
Coloscopy
2.1
29.4
397
2069
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
152.8
29.4
31
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
29.3
466
2595
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
16.7
29.2
47
28
A11CC03
ATC
alfacalcidol; systemic
6.5
28.6
76
117
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
28.6
757
5016
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.0
28.3
120
309
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
277.0
27.5
28
*
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
142.8
27.4
29
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
27.3
446
2497
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
26.9
235
994
A03FA01
ATC
metoclopramide; systemic, rectal
2.1
26.7
332
1664
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
26.4
710
4694
JN7SN
NOMESCO Finland
Somatostatin receptor SPECT
+∞
25.8
25
*
106
Kela drug reimbursment
Hypoparathyroidism
+∞
25.8
25
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
25.8
348
1802
E22.1
ICD-10 Finland
Hyperprolactinaemia
71.5
25.5
29
*
T73
ICPC
Neoplasm endocrine other/unspecified
91.9
25.4
28
*
A09AA02
ATC
multienzymes (lipase, protease etc.)
7.8
24.4
57
73
C17.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of small intestine
245.8
24.4
25
*
E21.0
ICD-10 Finland
Primary hyperparathyroidism
127.8
24.3
26
*
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
23.7
23
*
E22.80
ICD-10 Finland
Central precocious puberty
235.7
23.4
24
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.4
23.2
116
343
BF20A
NOMESCO Finland
NA
+∞
22.7
22
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.1
22.5
133
443
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
6.0
22.5
63
105
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.5
21.9
190
796
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.4
21.9
203
881
L03AB05
ATC
interferon alfa-2b; parenteral
23.5
21.8
31
13
C25.4
ICD-10 Finland
Malignant neoplasm: Endocrine pancreas
215.8
21.4
22
*
8240/3-C17.2
ICD-O-3
Neuroendocrine tumor, NOS, of ileum
215.8
21.4
22
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
21.3
677
4625
JFB30
NOMESCO Finland
Right hemicolectomy
8.9
21.1
45
50
C10AC01
ATC
colestyramine; oral
5.2
20.9
66
127
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.1
20.4
116
377
A02BC01
ATC
omeprazole; systemic
1.8
20.4
406
2406
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.5
20.3
73
162
A12AA04
ATC
calcium carbonate; oral
7.4
20.2
48
64
RD210
NOMESCO Finland
NA
3.4
20.1
102
306
J01MA12
ATC
levofloxacin; systemic
2.1
19.9
259
1310
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
8.2
19.7
44
53
R50.9
ICD-10 Finland
Fever, unspecified
1.9
19.6
341
1927
104
Kela drug reimbursment
Thyroid insufficiency
3.0
19.6
114
378
E30.1
ICD-10 Finland
Precocious puberty
196.0
19.3
20
*
N02AA05
ATC
oxycodone; systemic
2.3
19.3
184
809
JKA20
NOMESCO Finland
Cholecystectomy
5.8
19.2
55
95
R62.0
ICD-10 Finland
Delayed milestone
3.4
19.0
93
272
A04AA02
ATC
granisetron; systemic, transdermal
3.2
18.7
103
329
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.5
18.6
89
255
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
+∞
18.6
18
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
5.5
18.4
55
100
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
186.1
18.3
19
*
127
Kela drug reimbursment
Transplant complication
4.7
18.3
62
130
B03BA03
ATC
hydroxocobalamin; parenteral
3.4
18.2
89
260
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
7.6
17.9
42
55
7834C
ICD-9 Finland
Symptoms concerning nutrition, metabolism and development, Lack of expected normal physiological development[HÄIRIINTYNYT PITUUSKASVU]
32.2
17.7
23
7
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
17.7
147
604
102
Kela drug reimbursment
Diabetes insipidus
+∞
17.5
17
*
C03CA01
ATC
furosemide; systemic
1.9
17.5
305
1722
WX723
NOMESCO Finland
CPAP therapy
4.1
17.4
68
164
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
8.0
17.3
39
48
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.4
17.2
63
143
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
16.7
336
1985
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
+∞
16.5
16
*
E34.1
ICD-10 Finland
Other hypersecretion of intestinal hormones
+∞
16.5
16
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.2
16.5
51
97
121
Kela drug reimbursment
Severe hypofunction of sexual glands
5.5
16.5
49
89
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.9
16.4
100
343
E26.0
ICD-10 Finland
Primary hyperaldosteronism
166.3
16.3
17
*
8249/3-C17.9
ICD-O-3
Neuroendocrine tumor, grade 2 of small intestine, NOS
166.3
16.3
17
*
XX9AD
NOMESCO Finland
Complementary CT
166.3
16.3
17
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.4
16.3
59
133
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.1
16.1
63
153
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
8.8
16.1
34
38
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
16.0
254
1382
L01BC06
ATC
capecitabine; oral
3.9
15.9
65
164
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
15.5
370
2297
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
+∞
15.5
15
*
8246/3-C17.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of small intestine, NOS
+∞
15.5
15
*
E34.5
ICD-10 Finland
Androgen resistance syndrome
+∞
15.5
15
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
4.3
15.4
57
131
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
25.7
15.4
21
8
JAH00
NOMESCO Finland
Laparotomy
3.9
15.3
64
165
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
156.5
15.3
16
*
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
37.2
15.2
19
5
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
5.3
15.1
46
86
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
15.1
276
1576
UKC02
NOMESCO Finland
Cystoscopy
2.1
15.0
189
941
G02CB01
ATC
bromocriptine; systemic
6.4
15.0
39
60
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
5.5
15.0
44
79
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
22.9
14.9
21
9
WZC30
NOMESCO Finland
Teaching
2.0
14.8
204
1053
T99
ICPC
Endocr/metab/nutrit disease other
5.8
14.6
41
70
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
+∞
14.4
14
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
14.4
206
1077
C17.0
ICD-10 Finland
Malignant neoplasm: Duodenum
78.3
14.4
16
*
SPAT1377
SPAT
Polysomnography
3.7
14.3
63
170
JN4DD
NOMESCO Finland
Scout CT scan of torso
35.2
14.2
18
5
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.1
14.1
172
846
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
13.9
425
2811
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
6.6
13.9
35
52
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.7
13.8
60
161
-50
ICPC
Medication/prescr/renewal
3.0
13.7
81
273
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
13.7
189
977
L04AA01
ATC
[U] ciclosporin; systemic
5.4
13.5
40
73
A12AA06
ATC
calcium lactate gluconate; oral
136.8
13.3
14
*
L04AA06
ATC
mycophenolic acid; systemic
4.0
13.3
53
132
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.1
13.2
148
702
N04BC06
ATC
cabergoline; oral (dopamine agonists)
20.7
13.1
19
9
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
13.0
324
2027
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
12.9
136
627
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.7
12.8
55
146
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
6.7
12.8
32
47
E83.50
ICD-10 Finland
Hypercalcemia
7.7
12.8
29
37
H02AA02
ATC
fludrocortisone; oral
10.7
12.8
24
22
E27.0
ICD-10 Finland
Other adrenocortical overactivity
68.2
12.4
14
*
XF404
NOMESCO Finland
Ambulatory ECG
2.1
12.4
151
743
2592A
ICD-9 Finland
Other endocrine disorders, Carcinoid syndrome
+∞
12.4
12
*
BB1BQ
NOMESCO Finland
Extensive scintigraphy of parathyroid gland, 2 isotopes, SPECT and low-dose CT
+∞
12.4
12
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
+∞
12.4
12
*
2594A
ICD-9 Finland
Other endocrine disorders, Dwarfism, not elsewhere classified
+∞
12.4
12
*
E23.6
ICD-10 Finland
Other disorders of pituitary gland
+∞
12.4
12
*
UDC00
NOMESCO Finland
Ear microscopy
2.0
12.1
153
763
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
4.5
12.1
42
92
-44
ICPC
Preventive immunization/medic
2.1
12.1
140
675
N06AA09
ATC
amitriptyline; systemic
2.2
12.0
126
581
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
12.0
156
785
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.1
11.9
143
699
A02BC05
ATC
esomeprazole; systemic
1.5
11.9
511
3645
SPAT1325
SPAT
Vaccination
1.4
11.8
642
4805
R4190
NOMESCO Finland
Nutritional therapy
2.0
11.8
148
735
B81
ICPC
Anaemia vit B12/folate deficiency
3.4
11.8
57
168
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.0
11.6
45
110
A02BA02
ATC
ranitidine; systemic
1.8
11.5
225
1310
WX780
NOMESCO Finland
Remote monitoring CPAP
3.1
11.5
62
198
E28.3
ICD-10 Finland
Primary ovarian failure
63.4
11.5
13
*
G47.3
ICD-10 Finland
Sleep apnoea
1.7
11.4
244
1460
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
11.4
227
1329
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
+∞
11.3
11
*
8240/3-C34.9
ICD-O-3
Neuroendocrine tumor, NOS, of lung, NOS
+∞
11.3
11
*
E35.8
ICD-10 Finland
Disorders of other endocrine glands in diseases classified elsewhere
+∞
11.3
11
*
E25.01
ICD-10 Finland
Congenital adrenal hyperplasia
+∞
11.3
11
*
321
Kela drug reimbursment
Paricalcitol and cinacalcet
117.1
11.3
12
*
E21.1
ICD-10 Finland
Secondary hyperparathyroidism, not elsewhere classified
117.1
11.3
12
*
WX402
NOMESCO Finland
General anaesthesia
1.6
11.3
321
2075
R11
ICD-10 Finland
Nausea and vomiting
1.9
11.3
176
953
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
9.0
11.2
23
25
N02AX02
ATC
tramadol; systemic, rectal
1.5
11.2
508
3658
205
Kela drug reimbursment
Chronic hypertension
1.7
11.2
277
1726
C17.1
ICD-10 Finland
Malignant neoplasm: Jejunum
34.2
11.1
14
*
BCA30
NOMESCO Finland
Unilateral adrenalectomy
34.2
11.1
14
*
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.7
11.1
73
264
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
6.8
11.1
27
39
SPAT1153
SPAT
Removal of sutures
1.5
11.0
419
2899
C18.99
ICD-10 Finland
Malignant tumor in unspecified location in the colon other or unspecified histology
16.6
11.0
17
10
R06.0
ICD-10 Finland
Dyspnoea
1.6
11.0
328
2147
C18.09
ICD-10 Finland
Malignant tumor of caecum other or unspecified histology
24.4
11.0
15
6
B01AB10
ATC
tinzaparin; parenteral
2.4
10.9
95
400
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.6
10.9
27
40
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
5.3
10.9
32
59
F83
ICD-10 Finland
Mixed specific developmental disorders
2.9
10.8
67
233
N06AX16
ATC
venlafaxine; oral
1.8
10.8
207
1200
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
10.8
297
1905
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
5.9
10.8
29
48
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
4.3
10.7
39
90
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.0
10.7
62
207
SPAT1324
SPAT
Screening procedure
0.5
10.6
73
1429
H02AB06
ATC
prednisolone; systemic
1.4
10.6
645
4907
C18.90
ICD-10 Finland
Malignant tumor in unspecified location in the colon without histology
27.3
10.6
14
5
Z56.5
ICD-10 Finland
Uncongenial work
27.3
10.6
14
5
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
10.3
10.6
20
19
JF1BD
NOMESCO Finland
Very extensive small bowel CT
8.6
10.5
22
25
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.7
10.5
45
121
Z01.9
ICD-10 Finland
Special examination, unspecified
2.4
10.5
89
371
Z94.0
ICD-10 Finland
Kidney transplant status
4.3
10.5
38
88
E29.1
ICD-10 Finland
Testicular hypofunction
12.6
10.4
18
14
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
10.4
181
1018
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.9
10.3
60
202
E23.03
ICD-10 Finland
Lack of ACTH
+∞
10.3
10
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.4
10.2
48
139
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
10.2
328
2181
C18.19
ICD-10 Finland
Malignant tumor in appendix other or unspecified histology
15.6
10.2
16
10
RL140
NOMESCO Finland
NA
4.9
10.2
32
64
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
10.2
132
667
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.0
10.1
132
668
E87.6
ICD-10 Finland
Hypokalaemia
3.4
10.1
48
141
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
6.9
10.0
24
34
H05BX01
ATC
cinacalcet; oral
39.0
9.8
12
*
A11CC02
ATC
dihydrotachysterol; oral
39.0
9.8
12
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
9.8
758
5992
SPAT1312
SPAT
General health counselling
1.4
9.8
680
5278
A06AD11
ATC
lactulose; oral
1.8
9.8
165
917
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.0
9.7
127
644
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
5.9
9.7
26
43
K03.66
ICD-10 Finland
Tooth plaque
1.8
9.7
168
938
C25.2
ICD-10 Finland
Malignant neoplasm: Tail of pancreas
25.4
9.7
13
5
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
9.7
164
912
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
9.6
134
697
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
8.5
9.6
20
23
JFB20
NOMESCO Finland
Ileocaecal resection
9.3
9.6
19
20
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
9.5
139
734
158
Kela drug reimbursment
Everolimus
53.6
9.5
11
*
E23.2
ICD-10 Finland
Diabetes insipidus
53.6
9.5
11
*
Z51.5
ICD-10 Finland
Palliative care
2.6
9.5
68
261
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
4.1
9.5
35
83
WX110
NOMESCO Finland
Local anesthesy
1.4
9.4
1248
10727
L04AD01
ATC
ciclosporin; systemic
3.1
9.4
49
154
ZXA10
NOMESCO Finland
Bilateral
1.6
9.3
292
1928
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2.7
9.3
63
233
P05.1
ICD-10 Finland
Small for gestational age
6.2
9.3
24
38
D44.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Endocrine gland, unspecified
97.5
9.3
10
*
E27.5
ICD-10 Finland
Adrenomedullary hyperfunction
97.5
9.3
10
*
E340, C179
ICD-10 Finland
NA
+∞
9.3
9
*
8240/3-C20.9
ICD-O-3
Neuroendocrine tumor, NOS, of rectum, NOS
+∞
9.3
9
*
2520A
ICD-9 Finland
Disorders of parathyroid gland, Hyperparathyroidism
+∞
9.3
9
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.8
9.2
59
212
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
9.2
115
574
A41.9
ICD-10 Finland
Sepsis, unspecified
2.6
9.2
67
260
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
7.3
9.2
21
28
A55
ICPC
General and Unspecified, Local injection/infiltration
6.4
9.2
23
35
WZA10
NOMESCO Finland
Long statement of health and health related matters
3.7
9.2
38
100
ZX120
NOMESCO Finland
Intravenous
1.8
9.2
151
832
C03DA01
ATC
spironolactone; oral
1.9
9.1
130
679
R68.8
ICD-10 Finland
Other specified general symptoms and signs
5.7
9.1
25
43
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
9.1
107
520
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.5
9.0
68
267
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.0
9.0
49
159
A02BC02
ATC
pantoprazole; systemic
1.3
9.0
828
6702
XKC03
NOMESCO Finland
Water cystometry
3.1
9.0
48
154
B01AB05
ATC
enoxaparin; parenteral
1.5
9.0
348
2412
SPAT1301
SPAT
No procedures
1.4
8.9
531
3995
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.1
8.9
47
150
E0000UV
ATC
NA
1.4
8.9
704
5561
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.8
8.8
164
938
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
8.8
231
1458
JLC10
NOMESCO Finland
Distal pancreatectomy
18.1
8.8
13
7
D76
ICPC
Malignant neoplasm pancreas
23.4
8.8
12
5
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
8.8
135
728
SPAT1263
SPAT
Sampling
1.3
8.6
726
5784
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
8.6
101
490
N03AX16
ATC
pregabalin; oral
1.6
8.6
265
1742
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
3.0
8.6
47
154
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.4
8.6
74
312
8249/3-C17.2
ICD-O-3
Neuroendocrine tumor, grade 2 of ileum
48.7
8.6
10
*
Q87.19
ICD-10 Finland
Congenital malformation syndromes predominantly associated with short stature
48.7
8.6
10
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
8.6
196
1195
L04AX01
ATC
azathioprine; systemic
2.2
8.5
87
398
137
Kela drug reimbursment
Uraemia requiring dialysis
5.0
8.5
26
51
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.9
8.4
26
52
B03XA01
ATC
erythropoietin; parenteral
5.1
8.4
25
48
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.3
8.4
24
44
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
8.4
695
5520
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
8.7
8.3
17
19
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
8.3
275
1834
AA1AD
NOMESCO Finland
CT of head and brain
1.5
8.3
262
1730
C07AB02
ATC
metoprolol; systemic
1.6
8.3
215
1352
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
87.8
8.3
9
*
E21.2
ICD-10 Finland
Other hyperparathyroidism
87.8
8.3
9
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
8.3
163
952
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
8.3
120
634
K85
ICD-10 Finland
Acute pancreatitis
4.6
8.3
27
57
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.5
8.3
64
257
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
8.3
125
670
OAB72
NOMESCO Finland
Weight control and weight loss guidance
7.1
8.2
19
26
G44.2
ICD-10 Finland
Tension-type headache
1.6
8.2
196
1207
8249/3-C25.9
ICD-O-3
Neuroendocrine tumor, grade 2 of pancreas, NOS
+∞
8.2
8
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
+∞
8.2
8
*
E20.8
ICD-10 Finland
Other hypoparathyroidism
+∞
8.2
8
*
E83.51
ICD-10 Finland
Hypocalcemia
12.4
8.2
14
11
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
8.2
206
1288
A07AA02
ATC
nystatin; oral
2.2
8.1
82
374
BC00A
NOMESCO Finland
NA
9.2
8.1
16
17
JAH01
NOMESCO Finland
Laparoscopy
2.3
8.1
71
303
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
5.1
8.1
24
46
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
8.1
242
1581
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.5
8.1
59
230
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.3
8.0
68
287
XX4AW
NOMESCO Finland
NA
3.3
8.0
38
113
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.3
8.0
28
64
E23.05
ICD-10 Finland
Lack of TSH
32.5
8.0
10
*
8240/3-C18.2
ICD-O-3
Neuroendocrine tumor, NOS, of ascending colon
32.5
8.0
10
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
8.0
79
360
XA800
NOMESCO Finland
Neuropsychological investigation
1.9
7.9
105
539
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.7
7.9
150
865
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.2
7.9
28
65
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
7.8
215
1375
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.9
7.8
45
151
XKD00
NOMESCO Finland
Uroflowmetry
1.7
7.8
158
929
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.9
7.8
45
152
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
2.1
7.7
88
423
R53
ICD-10 Finland
Malaise and fatigue
1.5
7.7
291
2000
I15.9
ICD-10 Finland
Secondary hypertension, unspecified
6.4
7.7
19
29
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
7.7
280
1910
XF602
NOMESCO Finland
Bloodpressure monitoring
3.7
7.7
32
86
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
2.8
7.6
47
167
L01CB01
ATC
etoposide; systemic
10.5
7.6
14
13
C74.9
ICD-10 Finland
Malignant neoplasm: Adrenal gland, unspecified
43.8
7.6
9
*
L01XE10
ATC
[U] everolimus; oral
43.8
7.6
9
*
340
Kela drug reimbursment
Everolimus
43.8
7.6
9
*
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
7.5
121
664
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
2.8
7.5
46
163
S02.51
ICD-10 Finland
Fracture of tooth, open
1.8
7.5
135
767
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
5.8
7.5
20
34
T90
ICPC
Diabetes non-insulin dependent
1.6
7.5
221
1437
T10
ICPC
Growth delay
5.4
7.5
21
38
318
Kela drug reimbursment
Teriparatide
24.4
7.5
10
*
Q87.14
ICD-10 Finland
Noonan's syndrome
24.4
7.5
10
*
SPAT1260
SPAT
Consultation of another employee
1.5
7.4
277
1900
Y0099
ICD-8 Finland
Investigation of endocrine system and metabolism
8.6
7.4
15
17
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
7.4
157
938
N03AX09
ATC
lamotrigine; oral
2.0
7.3
88
434
E21
ICD-10 Finland
Hyperparathyroidism and other disorders of parathyroid gland
78.0
7.3
8
*
8240/3-C25.9
ICD-O-3
Neuroendocrine tumor, NOS, of pancreas, NOS
78.0
7.3
8
*
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
78.0
7.3
8
*
K65.0
ICD-10 Finland
Acute peritonitis
5.3
7.3
21
39
N05BA04
ATC
oxazepam; oral
1.4
7.3
321
2275
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
4.2
7.3
26
61
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
13.0
7.2
12
9
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.6
7.2
48
179
1522B
ICD-9 Finland
Malignant neoplasm of small intestine, including duodenum, Ileum[NEOPLASMA MALIGNUM ILEI,ALIA DEFINITA SEU NUD]
+∞
7.2
7
*
E26.9
ICD-10 Finland
Hyperaldosteronism, unspecified
+∞
7.2
7
*
E22.9
ICD-10 Finland
Hyperfunction of pituitary gland, unspecified
+∞
7.2
7
*
E34.4
ICD-10 Finland
Constitutional tall stature
+∞
7.2
7
*
E21.5
ICD-10 Finland
Disorder of parathyroid gland, unspecified
+∞
7.2
7
*
8249/3-C80.9
ICD-O-3
Neuroendocrine tumor, grade 2 of unknown primary site
+∞
7.2
7
*
BB1AN
NOMESCO Finland
Parathyroid gland isotope imaging, 1 isotope
+∞
7.2
7
*
E35.0
ICD-10 Finland
Disorders of thyroid gland in diseases classified elsewhere
+∞
7.2
7
*
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.4
7.2
55
222
SPAT1094
SPAT
Continuous Positive Airway Pressure
5.8
7.2
19
32
H02AB04
ATC
methylprednisolone; systemic
1.6
7.2
173
1070
N91.0
ICD-10 Finland
Primary amenorrhoea
8.1
7.2
15
18
Z99.2
ICD-10 Finland
Dependence on renal dialysis
8.1
7.2
15
18
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
10.6
7.2
13
12
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.1
7.1
36
113
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
4.2
7.1
25
58
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.4
7.1
59
247
SPAT1310
SPAT
Counselling related to known health issue
1.3
7.1
559
4379
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
6.1
7.1
18
29
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.5
7.0
51
200
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
7.0
92
470
ED1AA
NOMESCO Finland
Mandipular X-ray examination
7.1
7.0
16
22
JJA20
NOMESCO Finland
Open biopsy of liver
7.7
6.9
15
19
E03
ICD-10 Finland
Other hypothyroidism
2.1
6.9
76
362
M03BX01
ATC
baclofen; systemic
3.8
6.9
27
69
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
6.9
284
1988
TK800
NOMESCO Finland
Hemodialysis
3.2
6.9
34
105
N18.8
ICD-10 Finland
Other chronic renal failure
2.9
6.9
40
137
N06AB04
ATC
citalopram; systemic
1.5
6.8
256
1754
YHMAS
NOMESCO Finland
NA
4.6
6.8
22
47
TJD20
NOMESCO Finland
Change of gastrostomy tube
4.2
6.8
24
56
FM2CE
NOMESCO Finland
NA
2.0
6.8
77
373
H03BB01
ATC
carbimazole; oral
2.3
6.8
57
241
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
3.3
6.7
31
91
WX610
NOMESCO Finland
Patient controlled analgesia
5.0
6.7
20
39
KAC00
NOMESCO Finland
Nephrectomy
5.7
6.7
18
31
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
5.3
6.7
19
35
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.2
6.7
33
102
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
6.7
139
825
R03AC02
ATC
salbutamol; inhalant
1.3
6.7
886
7445
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.4
6.7
51
206
E30.8
ICD-10 Finland
Other disorders of puberty
38.9
6.7
8
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
6.7
131
768
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
6.5
6.6
16
24
5AB14
NOMESCO Finland
NA
6.5
6.6
16
24
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
4.7
6.6
21
44
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
16.2
6.6
10
6
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.5
6.6
48
189
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.0
6.6
76
370
V03AG01
ATC
sodium cellulose phosphate; systemic
4.9
6.6
20
40
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
5.9
6.6
17
28
WW500
NOMESCO Finland
Blood transfusion
2.2
6.6
66
301
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
5.5
6.6
18
32
A79
ICPC
Malignancy NOS
4.4
6.6
22
49
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
3.0
6.5
35
115
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
6.5
126
731
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.5
6.5
49
194
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.6
6.5
21
45
N06AX21
ATC
duloxetine; oral
1.7
6.5
136
810
BAA60
NOMESCO Finland
Total thyroidectomy
3.2
6.5
31
94
AA1AA
NOMESCO Finland
Head X-ray examination
4.8
6.5
20
41
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.8
6.5
108
600
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
6.4
53
223
SPAT1281
SPAT
Other administrative function
1.6
6.4
151
927
C08CA01
ATC
amlodipine; oral
1.4
6.4
327
2380
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.4
438
3346
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
9.8
6.4
12
12
C01BD07
ATC
dronedarone; oral
9.8
6.4
12
12
A01AB09
ATC
miconazole; local oral
1.7
6.4
118
679
GD2SN
NOMESCO Finland
Lung ventilation SPECT
6.7
6.4
15
22
R01AD08
ATC
fluticasone; nasal
1.4
6.4
385
2884
1CB02
NOMESCO Finland
NA
68.0
6.3
7
*
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
68.0
6.3
7
*
8246/3-C80.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of unknown primary site
68.0
6.3
7
*
E20.0
ICD-10 Finland
Idiopathic hypoparathyroidism
68.0
6.3
7
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
6.3
181
1170
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
6.3
121
702
C08CA02
ATC
felodipine; oral
1.9
6.3
90
473
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.2
6.3
64
294
197
Kela drug reimbursment
Sunitinib
13.9
6.3
10
7
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.4
6.3
339
2490
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
4.4
6.3
21
47
R4180
NOMESCO Finland
Podiatric therapy
4.4
6.3
21
47
K06.18
ICD-10 Finland
Another gingival hyperplasia
4.4
6.3
21
47
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
7.2
6.3
14
19
E000003
ATC
NA
1.9
6.2
84
436
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.6
6.2
41
153
-1
SPAT
NA
1.8
6.2
102
563
E23.08
ICD-10 Finland
Hypopituitarism
+∞
6.2
6
*
2522
FHL
Removal of parathyroidism or multiple parathyroidism (including removal of adenoma or total removal)
+∞
6.2
6
*
8246/3-C25.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of pancreas, NOS
+∞
6.2
6
*
E35.1
ICD-10 Finland
Disorders of adrenal glands in diseases classified elsewhere
+∞
6.2
6
*
E89.30
ICD-10 Finland
Postprocedural hypopituitarism
+∞
6.2
6
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
6.2
6
*
E20.1
ICD-10 Finland
Pseudohypoparathyroidism
+∞
6.2
6
*
E27.2
ICD-10 Finland
Addisonian crisis
+∞
6.2
6
*
R55
ICD-10 Finland
Syncope and collapse
1.7
6.2
136
822
XLA10
NOMESCO Finland
NA
2.3
6.2
53
226
Z50.0
ICD-10 Finland
Cardiac rehabilitation
4.8
6.2
19
39
ZX070
NOMESCO Finland
Intensity modified radiotherapy
3.3
6.2
28
82
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
4.3
6.1
21
48
Q87.4
ICD-10 Finland
Marfan syndrome
26.0
6.1
8
*
8240/3-C16.9
ICD-O-3
Neuroendocrine tumor, NOS, of stomach, NOS
26.0
6.1
8
*
H05AA02
ATC
teriparatide; parenteral
26.0
6.1
8
*
6402
FHL
Small bowel resection
26.0
6.1
8
*
J20
ICD-10 Finland
Acute bronchitis
1.7
6.1
131
787
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.2
6.1
59
268
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
6.1
450
3477
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.4
6.1
280
1999
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.9
6.1
33
110
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
6.1
260
1830
SPAT1238
SPAT
Brief therapy
2.6
6.1
40
149
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
2.3
6.1
53
230
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.5
6.1
43
166
H52.0
ICD-10 Finland
Hypermetropia
2.2
6.0
55
242
L02AE02
ATC
leuprorelin; implant, parenteral
2.4
6.0
49
203
C07AB07
ATC
bisoprolol; oral
1.3
6.0
464
3610
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.6
6.0
170
1097
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.8
6.0
97
535
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
435
982
5.08
175.11
6.1
3.7
1.2
1.2
mmol/l
0.70
396
844
557
1548
4.32
172.47
2.9
2.1
316.7
364.1
nmol/l
5.36
533
1430
430
1284
3.77
116.84
4.1
2.9
—
—
—
0
0
296
683
4.67
113.73
2.3
1.5
6.5
7.0
u/l
0.29
201
484
179
297
6.23
99.02
4.3
4.8
2.7
2.2
mmol/l
1.13
139
175
570
2319
2.85
90.60
10.1
8.4
1.2
1.2
mmol/l
0.06
539
2196
883
4545
2.47
86.12
4.5
3.1
2.4
2.4
mmol/l
0.06
827
4024
294
848
3.70
82.51
2.3
1.5
11.8
19.3
iu/l
4.76
213
646
164
351
4.78
68.22
3.6
3.7
56.3
54.7
%
0.69
164
351
1732
12789
2.53
64.67
5.7
3.7
14.9
14.6
pmol/l
4.86
1606
11650
1124
6977
2.15
64.52
12.0
8.2
1.2
1.2
mmol/l
3.31
1046
6436
46
20
22.58
61.02
2.1
1.7
—
—
—
0
0
138
282
4.96
60.55
2.8
2.5
16.9
16.9
%
0.05
70
167
283
964
3.10
60.14
3.4
3.3
4.6
4.7
pmol/l
0.80
253
858
81
98
8.22
59.37
2.4
1.7
0.1
0.2
nmol/l
1.08
63
71
1169
7522
2.08
59.11
11.6
8.1
1.2
1.2
mmol/l
0.83
802
6586
373
1554
2.58
53.93
3.4
3.3
0.2
0.2
g/l
0.02
357
1484
1519
11006
2.10
52.76
11.5
6.6
100.1
88.9
u/l
8.32
1446
10340
272
1002
2.84
49.86
3.1
1.9
10.5
12.3
nmol/l
2.26
220
852
252
893
2.94
49.58
2.6
1.4
363.8
313.7
mu/l
1.32
223
795
1012
6472
1.95
48.78
4.1
2.5
74.6
72.9
nmol/l
1.20
945
5956
733
4204
2.03
48.32
4.4
3.6
0.0
0.0
estimate
0.05
426
1483
946
5963
1.94
47.12
8.0
5.6
36.3
36.5
g/l
0.35
867
5577
425
1993
2.31
46.84
3.5
2.6
21.4
22.5
%
0.92
378
1775
1266
8885
1.90
44.37
10.0
7.1
31.6
31.5
%
0.15
1223
8390
609
3377
2.02
43.26
4.1
2.7
6.3
6.8
e6/l
0.36
551
2950
489
2551
2.09
40.71
2.1
1.6
41795342.7
19991130.7
pmol/l
0.32
390
2151
430
2136
2.17
40.66
3.5
2.5
2.5
2.4
g/l
0.32
397
1993
48
8
58.98
40.64
2.7
2.1
44.4
98.0
pmol/l
—
34
8
1235
8748
1.84
40.37
9.6
6.9
53.3
53.7
%
0.53
1193
8291
459
2360
2.11
39.59
3.5
2.5
12.9
13.6
umol/l
1.15
423
2217
1364
10004
1.85
39.34
13.8
9.5
3.8
3.8
e9/l
0.21
1237
8582
450
2308
2.11
39.01
9.6
6.4
0.8
0.8
mmol/l
0.69
427
2171
268
1106
2.52
38.81
6.9
5.4
73.3
66.0
ng/l
0.53
226
1022
146
433
3.41
38.55
1.4
1.4
304.7
312.0
ug/g
0.15
99
232
145
436
3.36
37.45
2.0
1.5
—
—
—
0
0
1826
14929
2.14
35.80
6.1
4.3
1.8
2.0
mu/l
1.30
1705
13860
1043
7189
1.77
35.67
10.4
6.4
12.6
14.1
umol/l
1.09
985
6724
666
4132
1.80
31.81
2.8
2.5
3.1
2.8
mg/l
3.17
590
3578
70
140
4.94
31.42
1.6
1.5
3.4
5.1
umol/l
3.39
65
125
717
4599
1.75
30.22
4.4
3.4
0.3
0.3
e6/l
0.45
600
3413
1232
9161
1.68
29.79
7.5
5.6
6.4
6.4
mmol/l
0.13
1175
8454
779
5136
1.72
29.61
1.5
1.6
1.1
2.5
u/ml
4.06
184
1144
82
197
4.12
29.33
3.7
3.8
86.7
1477.8
u/ml
0.59
71
187
1464
11514
1.69
27.47
5.4
4.0
10.9
9.9
mm/h
1.99
1356
10695
666
4297
1.71
26.84
3.5
2.6
56.5
56.2
u/l
0.04
602
3978
709
4669
1.69
26.38
1.8
1.5
1.9
2.0
g/l
0.14
366
2641
393
2196
1.88
25.64
4.4
2.8
2.4
2.4
mmol/l
0.87
354
1895
1549
12471
1.69
25.46
5.8
4.7
38.0
38.5
mmol/mol
1.27
1444
11615
853
5956
1.62
24.86
4.3
3.4
—
—
—
0
0
98
302
3.22
24.30
1.8
1.9
—
—
—
0
0
1803
15225
1.84
24.10
23.5
14.9
13.6
13.4
%
5.59
1776
14930
503
3091
1.74
23.72
4.2
3.8
923.7
1184.5
ng/l
1.32
423
2603
87
264
3.26
22.14
1.8
1.9
—
—
—
0
0
1063
8008
1.55
21.23
4.3
3.4
0.0
0.0
estimate
0.00
441
1479
1064
8018
1.54
21.22
5.5
4.7
0.0
0.0
estimate
0.50
443
1540
37
59
6.12
21.17
1.5
1.7
—
—
—
0
0
1068
8090
1.53
20.55
4.3
3.4
0.0
0.0
estimate
0.50
437
1490
36
58
6.05
20.39
1.5
1.7
—
—
—
0
0
60
152
3.88
20.02
1.4
1.3
476.5
343.0
pmol/l
0.31
50
118
27
33
7.96
19.56
2.4
2.0
—
—
—
0
0
190
902
2.13
19.45
18.6
14.4
1.4
1.1
mg/l
4.04
179
871
323
1840
1.81
19.41
5.5
4.3
1.6
1.6
%
0.06
288
1689
648
4437
1.58
19.36
4.1
3.2
34.8
49.5
ng/l
0.59
432
2641
45
97
4.54
18.54
1.6
1.7
—
—
—
0
0
88
301
2.89
18.28
1.7
1.4
0.3
0.4
nmol/l
0.66
68
242
37
69
5.23
18.02
1.5
1.6
—
—
—
0
0
195
967
2.03
17.75
2.0
1.7
—
—
—
0
0
1054
8144
1.48
17.26
4.0
2.9
98.4
85.4
ug/l
1.30
963
7611
104
402
2.56
17.09
12.0
7.5
3557.3
279.3
iu/ml
0.60
16
53
93
344
2.67
16.69
2.1
1.9
—
—
—
0
0
112
456
2.44
16.50
2.3
1.9
—
—
—
0
0
112
458
2.43
16.34
2.3
1.9
—
—
—
0
0
267
1512
1.80
16.22
4.7
3.0
9.4
9.9
g/l
1.51
244
1405
62
186
3.27
16.13
1.5
1.5
—
—
—
0
0
526
3638
1.52
14.29
1.8
1.7
1.5
1.3
mmol/l
2.77
368
3164
411
2694
1.58
14.23
2.8
2.8
101.8
111.3
ug/g
0.37
308
2149
193
1033
1.88
14.02
3.6
4.2
9.9
22.8
ug/l
0.82
145
826
69
240
2.82
13.96
4.3
3.1
—
—
—
0
0
327
2048
1.63
13.64
2.5
1.7
1573.0
1158.0
nmol/l
9.81
238
1538
74
271
2.68
13.59
1.7
1.5
—
—
—
0
0
85
341
2.46
12.97
12.4
7.3
379.4
1065.5
u/ml
—
9
33
211
1189
1.78
12.96
2.4
1.8
1.1
1.2
g/l
0.41
198
1111
87
355
2.41
12.80
2.8
2.3
131.8
132.0
g/l
0.03
80
289
1304
10811
1.40
12.76
5.7
4.0
1165.1
1747.6
e6/l
0.23
24
129
69
252
2.69
12.75
4.1
3.0
8.5
10.0
%
0.65
43
206
98
426
2.27
12.50
2.0
2.0
1.9
2.3
ug/l
0.17
80
374
1834
16241
1.57
12.44
22.4
13.3
3.9
3.9
mmol/l
0.03
1787
15715
451
3100
1.50
12.40
3.3
3.1
1743.9
5379.2
umol/l
2.33
405
2745
1831
16216
1.57
12.33
22.1
13.3
139.4
139.5
mmol/l
1.07
1790
15738
57
201
2.77
11.30
2.4
1.6
283.6
289.2
mosm/kgh2o
1.16
48
152
51
175
2.85
10.64
1.8
1.6
—
—
—
0
0
28
66
4.12
10.38
9.4
8.5
2.1
2.5
mg/l
0.49
23
55
63
246
2.51
10.24
1.7
1.4
—
—
—
0
0
25
55
4.41
10.11
6.1
6.7
—
—
—
0
0
25
55
4.41
10.11
6.2
7.0
—
—
—
0
0
241
1505
1.61
10.06
5.1
5.0
248.2
263.6
u/l
0.57
224
1437
671
5142
1.37
9.80
4.4
3.7
30.8
32.1
u/l
0.65
627
4909
56
212
2.58
9.71
1.7
1.6
—
—
—
0
0
297
1969
1.52
9.52
14.0
7.6
1.2
1.1
mmol/l
0.20
212
1438
333
2264
1.49
9.46
2.2
1.9
—
—
—
0
0
1892
17115
1.51
8.97
14.5
9.2
26.3
25.7
u/l
0.51
1831
16523
21
45
4.52
8.78
9.7
7.8
—
—
—
0
0
27
71
3.69
8.67
13.0
7.7
—
—
—
0
0
20
44
4.40
8.11
1.7
2.1
1.8
2.8
mg/l
0.34
14
38
20
44
4.40
8.11
1.7
2.1
1.0
1.3
mg/l
0.28
14
34
20
44
4.40
8.11
1.7
2.1
1.1
1.2
mg/l
0.07
13
38
20
44
4.40
8.11
1.7
2.1
1.6
6.5
mg/l
2.64
15
34
20
44
4.40
8.11
1.7
2.1
3.5
3.9
mg/l
0.10
13
33
20
44
4.40
8.11
1.7
2.1
0.9
0.7
mg/l
0.17
14
36
20
44
4.40
8.11
1.7
2.1
0.9
1.2
mg/l
0.38
15
38
20
44
4.40
8.11
1.7
2.1
1.2
3.0
mg/l
1.08
14
37
20
44
4.40
8.11
1.7
2.1
0.9
1.6
mg/l
0.66
15
38
502
3788
1.36
7.81
2.5
2.3
146.4
256.2
u/l
3.84
460
3596
23
59
3.78
7.66
1.3
1.9
20.3
19.5
nmol/l
—
8
19
1213
10353
1.29
7.61
5.1
3.3
49.5
38.5
u/l
2.62
1130
9800
31
98
3.07
7.54
2.1
1.3
—
—
—
0
0
36
125
2.80
7.44
1.2
1.1
83.0
149.9
u/l
0.76
28
92
60
266
2.20
7.42
3.5
3.9
34.1
40.9
mg/l
0.24
25
223
60
266
2.20
7.42
3.6
3.9
52.1
72.5
mg/l
0.39
25
223
63
286
2.15
7.36
1.2
1.2
—
—
—
0
0
82
412
1.95
7.29
2.0
1.3
—
—
—
0
0
401
2957
1.37
7.15
1.6
1.4
21.8
20.4
nmol/l
0.97
339
2534
151
921
1.62
6.95
2.6
3.1
66.1
66.2
g/l
0.04
140
850
227
1519
1.49
6.92
1.6
1.3
330.2
257.1
u/ml
0.56
207
1421
143
862
1.64
6.90
6.1
7.1
92.7
91.4
%
0.28
136
830
28
88
3.09
6.90
2.5
2.5
660.2
611.5
ml
0.23
22
61
266
1844
1.44
6.76
6.7
4.4
6.0
7.0
umol/l
0.69
206
1553
254
1751
1.45
6.65
12.5
7.7
23.4
23.8
mmol/l
1.55
249
1663
155
963
1.59
6.63
5.0
3.8
219.5
181.2
ng/l
0.32
144
868
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
81
422
1.88
6.50
7.1
10.5
0.3
0.3
u/ml
0.11
55
240
27
87
3.01
6.40
5.0
5.3
—
—
—
0
0
437
3332
1.33
6.19
2.9
2.6
2.1
1.2
mg/l
0.94
316
2440
24
613
0.37
5.98
1.2
1.4
—
—
—
0
0
19
51
3.61
5.98
2.0
1.4
2.7
5.2
%
—
7
13
77
408
1.85
5.90
1.7
1.3
9.2
4.0
ug/l
1.10
70
387
28
97
2.80
5.87
2.1
1.5
28.7
38.7
%
0.72
19
67
95
1486
0.60
5.72
1.5
1.5
—
—
—
0
0
558
4445
1.28
5.65
3.9
3.7
6.9
7.9
mmol/l
5.11
464
3861
2063
19282
1.65
5.52
28.1
17.3
264.3
259.8
e9/l
2.02
2018
18656
43
189
2.21
5.51
1.2
1.2
—
—
—
0
0
1502
13398
1.26
5.51
19.5
9.9
90.3
90.8
ml/min/173m2
0.35
1304
10358
15
36
4.03
5.49
3.9
3.4
—
—
—
0
0
96
1482
0.61
5.49
6.4
5.7
—
—
—
0
0
2063
19299
1.63
5.27
28.0
17.3
4.5
4.5
e12/l
3.84
2016
18615
29
109
2.58
5.24
2.6
6.2
76.4
89.0
mg/l
0.42
24
100
333
2502
1.33
5.17
1.3
1.2
33.6
26.0
iu/ml
0.33
90
712
2063
19306
1.62
5.17
28.2
17.3
6.9
6.8
e9/l
0.28
2017
18626
34
139
2.37
5.16
2.0
1.6
69.0
54.9
%
1.24
23
99
2063
19309
1.62
5.12
28.4
17.5
132.3
134.5
g/l
9.93
2041
19039
85
488
1.70
5.01
2.7
2.0
—
—
—
0
0
38
167
2.21
4.91
1.8
1.4
0.8
0.8
u/ml
0.02
12
50
1850
17006
1.32
4.90
19.9
11.7
21.0
22.6
mg/l
1.23
1496
12778
16
44
3.52
4.89
4.0
6.0
—
—
—
0
0
51
253
1.96
4.81
5.0
3.0
682.6
564.5
e6/l
0.71
44
188
224
1608
1.38
4.67
2.2
1.9
—
—
—
0
0
297
2228
1.33
4.65
12.6
7.4
1.0
1.5
mmol/l
1.38
221
1771
90
536
1.64
4.65
2.7
1.9
79.3
97.1
u/ml
0.52
12
69
50
250
1.95
4.63
5.0
3.0
0.2
0.2
e9/l
0.42
44
188
196
1381
1.40
4.57
1.3
1.2
119.3
160.1
iu/ml
0.66
62
497
45
220
1.99
4.45
1.7
1.2
—
—
—
0
0
27
107
2.45
4.42
1.6
1.6
—
—
—
0
0
107
675
1.55
4.37
2.4
1.6
—
—
—
0
0
77
448
1.68
4.37
4.3
3.3
37.2
33.5
umol/l
0.85
68
392
25
96
2.52
4.37
1.2
1.1
1.1
1.1
ratio
0.25
15
43
14
38
3.56
4.36
1.8
1.5
—
—
—
0
0
46
229
1.95
4.33
1.9
1.7
—
—
—
0
0
45
223
1.96
4.30
1.2
1.4
—
—
—
0
0
10
21
4.60
4.29
6.2
6.5
27.8
19.9
ug/min
—
10
15
308
2349
1.30
4.29
1.3
1.2
6.0
10.7
u/ml
1.09
118
860
65
365
1.74
4.20
2.7
2.5
—
—
—
0
0
104
662
1.54
4.10
2.5
1.7
268.5
188.9
u/ml
1.75
64
335
29
125
2.25
3.97
1.2
1.1
—
—
—
0
0
27
113
2.31
3.95
1.2
1.6
—
—
—
0
0
13
36
3.49
3.95
1.2
1.2
—
—
—
0
0
86
529
1.59
3.95
2.5
2.0
1.2
1.4
g/l
0.89
70
470
96
606
1.55
3.94
2.2
1.7
0.2
0.2
g/l
0.25
91
578
42
210
1.94
3.93
4.2
2.6
1006.3
760.8
e6/l
—
7
44
168
1186
1.39
3.90
1.2
1.1
—
44.1
—
0
9
22
85
2.51
3.82
1.3
1.5
4.0
6.7
u/l
—
9
44
97
621
1.53
3.75
2.2
1.7
1.2
1.2
g/l
0.08
91
590
8
11
7.02
3.75
1.6
1.8
104.1
94.1
ng/l
—
8
11
22
86
2.48
3.74
4.3
3.0
823.8
1021.7
u/ml
0.44
22
86
8
12
6.43
3.56
5.1
1.3
—
—
—
0
0
214
1598
1.32
3.49
2.1
1.8
—
—
—
0
0
68
411
1.61
3.40
2.0
3.6
34.0
3491.5
u/ml
0.79
55
347
313
2464
1.26
3.39
4.6
3.9
30.5
30.3
s
0.38
300
2409
65
389
1.63
3.38
1.8
2.3
—
—
—
0
0
7
10
6.75
3.27
3.9
5.8
—
—
—
0
0
19
75
2.45
3.19
1.4
1.7
—
875521.4
—
0
7
72
451
1.55
3.12
1.3
1.4
—
—
—
0
0
72
451
1.55
3.12
1.3
1.4
—
—
—
0
0
43
240
1.74
2.93
1.9
1.7
—
—
—
0
0
6
9
6.43
2.79
3.5
2.0
—
—
—
0
0
312
3555
0.82
2.74
4.2
3.5
1.0
1.0
kg/l
0.40
66
570
11
35
3.03
2.74
1.5
2.2
—
—
—
0
0
20
88
2.20
2.69
1.4
2.5
228.4
145.9
umol/l
—
7
51
56
821
0.65
2.68
1.5
1.9
—
—
—
0
0
186
1416
1.29
2.67
2.7
2.3
32.4
37.3
u/l
0.43
170
1192
18
77
2.26
2.58
1.4
1.1
270.1
97.2
u/l
0.39
18
67
36
199
1.75
2.57
2.0
1.9
—
—
—
0
0
26
130
1.94
2.53
1.2
1.2
—
—
—
0
0
11
37
2.87
2.51
1.2
1.1
—
—
—
0
0
16
66
2.34
2.49
2.6
3.8
92.5
153.4
ug/l
0.78
16
66
26
131
1.92
2.48
1.2
1.2
81.5
77.6
%
0.19
26
131
26
131
1.92
2.48
1.3
1.2
—
—
—
0
0
8
20
3.86
2.47
1.9
1.3
—
—
—
0
0
35
195
1.74
2.45
1.4
1.5
—
—
—
0
0
100
1293
0.73
2.43
22.8
21.4
1.2
1.3
inr
0.26
19
196
7
16
4.22
2.39
2.7
2.7
—
—
—
0
0
21
100
2.03
2.35
4.2
2.1
1.6
2.2
u/field
0.46
16
52
405
3396
1.18
2.33
5.3
4.2
14.7
14.1
mg/mmol
0.03
254
2219
597
5182
1.15
2.19
1.9
1.8
95.3
96.0
pmol/l
0.13
331
2714
48
691
0.66
2.16
15.5
7.5
0.6
0.7
%
0.46
48
672
107
780
1.34
2.15
1.8
1.8
—
—
—
0
0
1788
16694
1.18
2.15
18.8
13.6
39.2
39.7
%
2.50
1315
13461
5
9
5.35
2.15
6.4
2.4
—
—
—
0
0
5
9
5.35
2.15
1.0
1.1
—
—
—
0
0
29
160
1.75
2.13
1.9
1.6
—
—
—
0
0
50
318
1.52
2.12
1.3
1.2
—
5.1
—
0
24
74
512
1.40
2.06
4.3
3.6
9.8
8.2
umol/l
0.40
64
412
17
79
2.08
2.05
1.3
1.3
—
—
—
0
0
78
546
1.39
2.04
1.6
1.5
—
—
—
0
0
172
1354
1.24
1.93
2.6
2.3
9397.3
7287.5
u/l
0.20
56
525
10
38
2.54
1.86
2.4
1.6
—
—
—
0
0
6
16
3.61
1.86
1.2
1.3
—
—
—
0
0
14
63
2.15
1.84
1.4
1.2
—
—
—
0
0
7
22
3.07
1.80
1.3
1.9
—
—
—
0
0
29
169
1.66
1.80
2.6
4.0
74.0
83.4
u/ml
0.08
12
49
99
1218
0.77
1.76
1.5
1.3
—
—
—
0
0
15
71
2.04
1.75
1.3
1.3
—
—
—
0
0
110
833
1.28
1.73
1.5
1.5
—
—
—
0
0
188
2148
0.83
1.73
3.7
4.1
22.9
21.1
%
1.00
99
977
12
52
2.23
1.72
1.5
2.1
200.3
205.2
u/l
0.10
12
52
325
2748
1.16
1.70
4.0
3.1
4.0
2.7
e6/l
0.81
192
1498
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
24
135
1.72
1.70
1.3
1.2
—
—
—
0
0
62
433
1.39
1.69
2.0
1.9
2.3
4.6
iu/l
4.55
23
151
65
459
1.37
1.66
2.4
2.8
3.6
3.5
mmol/l
0.55
59
435
5
13
3.71
1.65
5.6
4.9
5.3
7.5
mmol/l
—
5
13
54
370
1.41
1.64
1.3
1.2
12.6
183.2
iu/ml
4.95
19
117
6
19
3.04
1.59
1.2
1.1
—
—
—
0
0
37
237
1.51
1.59
1.1
1.1
1.4
1.5
g/l
0.08
37
218
64
455
1.36
1.58
2.5
2.6
227.1
447.0
ug/l
1.11
57
427
128
1505
0.81
1.58
3.6
3.8
32.9
32.3
%
0.23
94
1040
177
1431
1.21
1.58
10.4
10.3
1.6
1.3
mmol/l
1.45
169
1339
5
14
3.44
1.55
1.2
1.3
—
—
—
0
0
39
255
1.48
1.53
1.4
1.1
—
—
—
0
0
44
295
1.44
1.52
1.4
1.4
—
—
—
0
0
6
20
2.89
1.51
4.3
4.4
3.1
3.9
mg/l
—
6
20
14
247
0.54
1.50
1.8
1.5
—
—
—
0
0
64
460
1.35
1.49
2.6
2.9
10.6
12.5
e6/l
0.13
47
339
64
461
1.35
1.47
2.7
2.9
328.6
8604.1
e6/l
0.49
51
351
9
37
2.35
1.44
1.2
1.1
—
—
—
0
0
256
2159
1.16
1.41
1.8
1.7
1.5
1.4
%
1.03
219
1929
22
128
1.66
1.41
2.1
3.5
—
—
—
0
0
22
128
1.66
1.41
2.1
3.5
—
—
—
0
0
84
1020
0.78
1.40
1.7
1.5
—
—
—
0
0
6
134
0.43
1.39
1.0
1.3
—
—
—
0
0
6
22
2.63
1.37
1.3
1.2
—
—
—
0
0
42
286
1.42
1.36
1.3
1.3
1.9
4.3
u/ml
1.37
18
107
10
45
2.14
1.34
1.2
1.6
—
—
—
0
0
5
17
2.83
1.30
1.4
1.2
—
—
—
0
0
76
922
0.79
1.28
1.6
1.5
—
—
—
0
0
76
921
0.79
1.27
1.6
1.5
—
—
—
0
0
76
920
0.79
1.26
1.6
1.4
—
—
—
0
0
1481
13819
1.10
1.25
4.5
3.7
5.7
5.7
mmol/l
0.25
1338
12642
25
156
1.55
1.25
1.3
1.2
—
—
—
0
0
25
156
1.55
1.25
1.3
1.2
—
—
—
0
0
25
156
1.55
1.25
1.3
1.2
—
—
—
0
0
25
156
1.55
1.25
1.3
1.2
—
—
—
0
0
76
918
0.79
1.24
1.6
1.5
—
—
—
0
0
825
7505
1.09
1.23
5.1
4.0
—
—
—
0
0
178
1478
1.17
1.22
1.0
1.1
—
—
—
0
0
25
157
1.54
1.22
1.3
1.2
—
—
—
0
0
7
137
0.49
1.21
1.6
2.7
106.6
105.5
mmol/l
—
7
137
1517
14190
1.10
1.16
3.7
3.7
—
—
—
0
0
5
19
2.53
1.16
1.4
1.3
—
—
—
0
0
14
76
1.78
1.16
1.1
1.1
—
—
—
0
0
611
5498
1.10
1.15
1.8
1.8
—
—
—
0
0
39
272
1.39
1.14
1.5
1.5
—
—
—
0
0
79
611
1.25
1.13
1.1
1.1
0.9
9.1
u/ml
—
6
92
55
679
0.77
1.10
1.7
1.6
3.3
4.3
mg/l
0.41
39
463
18
109
1.59
1.04
1.3
1.2
—
—
—
0
0
39
278
1.36
1.03
3.6
2.6
69.9
99.0
ug/min
0.27
27
181
16
95
1.62
1.00
1.0
1.1
1217.9
1486.9
miu/ml
0.44
16
95
15
88
1.64
0.98
1.0
1.2
98.9
82.1
%
—
8
40
18
111
1.56
0.98
1.2
1.2
—
—
—
0
0
20
127
1.52
0.96
1.7
1.6
—
—
—
0
0
39
282
1.34
0.95
1.3
1.3
2.2
4.3
u/ml
2.38
21
131
45
333
1.31
0.94
1.9
2.1
8.4
11.1
mg/l
0.99
38
309
12
67
1.73
0.93
1.1
1.4
—
264.3
—
0
7
6
27
2.14
0.91
1.2
1.1
—
—
—
0
0
233
2478
0.89
0.90
2.0
2.1
—
—
—
0
0
14
83
1.63
0.89
1.1
1.3
—
—
—
0
0
356
3702
0.91
0.89
2.3
2.3
—
—
—
0
0
15
91
1.59
0.88
1.1
1.1
96.3
89.4
%
—
8
41
8
41
1.88
0.87
1.5
1.1
—
—
—
0
0
38
475
0.77
0.87
1.2
1.9
—
—
—
0
0
194
1669
1.13
0.87
10.1
8.2
105.1
104.8
mmol/l
0.38
189
1634
17
107
1.53
0.86
6.5
4.6
—
—
—
0
0
54
416
1.26
0.85
1.2
1.1
—
—
—
0
0
335
2976
1.10
0.84
1.5
1.5
—
—
—
0
0
9
144
0.60
0.79
1.1
1.1
—
—
—
0
0
11
64
1.66
0.76
1.1
1.4
—
47.5
—
0
8
388
3988
0.92
0.76
3.5
2.4
—
—
—
0
0
20
135
1.43
0.75
1.3
1.3
—
—
—
0
0
1452
14266
0.94
0.75
4.4
4.0
2.7
2.7
mmol/l
3.32
1310
13230
48
373
1.24
0.73
1.1
1.1
0.7
4.0
u/ml
2.47
13
152
102
852
1.16
0.73
1.7
1.8
—
—
—
0
0
38
287
1.28
0.73
1.1
1.1
3.4
7.5
iu/ml
—
8
51
20
137
1.41
0.71
1.3
1.3
—
—
—
0
0
316
2831
1.09
0.68
4.1
3.0
0.9
1.1
e6/l
0.43
185
1575
83
924
0.86
0.67
2.0
2.3
5.3
7.1
ug/l
0.88
71
812
24
174
1.33
0.63
1.2
1.1
—
—
—
0
0
38
295
1.24
0.61
1.2
1.1
—
—
—
0
0
28
209
1.29
0.61
1.1
1.1
—
—
—
0
0
1430
14016
0.95
0.61
4.3
3.6
1.4
1.5
mmol/l
1.98
1293
13050
153
1333
1.11
0.60
7.9
9.7
0.6
0.8
mmol/l
0.22
122
1046
1370
13443
0.95
0.60
3.9
3.4
1.3
1.2
mmol/l
3.58
1232
12497
8
51
1.51
0.58
3.3
1.8
—
—
—
0
0
8
51
1.51
0.58
3.3
1.8
—
—
—
0
0
397
4030
0.94
0.57
2.4
2.4
—
—
—
0
0
237
2452
0.92
0.57
3.2
3.7
370.3
587.0
ng/l
0.86
150
1688
8
52
1.48
0.57
1.6
1.3
—
—
—
0
0
8
52
1.48
0.57
1.6
1.3
—
—
—
0
0
73
807
0.87
0.57
12.5
11.6
1.0
1.3
%
2.65
73
801
23
169
1.31
0.56
1.1
1.2
41.1
34.2
mg/l
0.33
14
132
113
976
1.12
0.54
1.7
1.9
—
—
—
0
0
152
1336
1.10
0.53
8.0
9.6
13.2
13.3
kpa
0.12
146
1285
1446
14143
0.95
0.53
4.3
3.7
4.5
4.6
mmol/l
3.81
1310
13246
152
1337
1.10
0.52
8.0
9.6
5.3
5.2
kpa
0.64
146
1284
6
38
1.52
0.52
1.7
1.5
—
—
—
0
0
20
146
1.32
0.52
1.0
1.0
—
—
—
0
0
66
553
1.15
0.50
1.7
1.9
40.7
38.9
u/l
0.31
59
506
297
2693
1.07
0.50
4.6
4.6
1.6
2.7
ug/l
2.11
256
2403
26
199
1.26
0.49
1.2
1.1
92.0
93.2
%
0.11
26
188
13
89
1.41
0.49
1.5
1.4
1.0
1.0
g/l
0.08
13
89
13
89
1.41
0.49
1.6
1.7
—
—
—
0
0
7
45
1.50
0.47
4.4
2.3
—
—
—
0
0
7
45
1.50
0.47
1.0
1.2
—
—
—
0
0
60
503
1.15
0.46
1.1
1.1
8.2
9.0
u/ml
0.10
36
273
31
361
0.82
0.46
2.5
2.4
—
—
—
0
0
22
266
0.79
0.46
1.1
1.1
—
—
—
0
0
21
158
1.28
0.46
1.0
1.1
—
—
—
0
0
10
66
1.46
0.45
1.5
1.3
—
—
—
0
0
24
286
0.81
0.45
1.7
1.6
9510.0
13968.2
e6/l
0.64
14
210
24
286
0.81
0.45
1.5
1.6
6.8
7.3
mmol/l
0.65
19
178
26
202
1.24
0.45
1.1
1.0
—
—
—
0
0
7
49
1.38
0.44
1.0
1.2
—
—
—
0
0
197
2025
0.93
0.43
1.8
2.0
—
—
—
0
0
26
203
1.23
0.43
2.6
1.8
—
—
—
0
0
8
54
1.43
0.42
3.4
1.8
—
—
—
0
0
10
67
1.44
0.42
1.5
1.3
—
—
—
0
0
77
826
0.89
0.42
1.3
1.3
225.5
241.8
miu/ml
0.15
36
410
75
804
0.89
0.41
12.1
11.7
0.6
0.7
%
0.61
75
799
112
1174
0.91
0.40
1.5
1.4
—
—
—
0
0
8
58
1.33
0.40
1.4
1.2
—
—
—
0
0
38
312
1.17
0.40
1.4
1.3
—
—
—
0
0
10
68
1.42
0.40
4.5
1.8
—
—
—
0
0
10
68
1.42
0.40
4.5
1.8
—
—
—
0
0
10
68
1.42
0.40
4.5
1.8
—
—
—
0
0
10
68
1.42
0.40
4.4
1.8
—
—
—
0
0
9
63
1.38
0.38
1.1
1.4
—
—
—
0
0
21
163
1.24
0.38
1.1
1.1
182.2
215.4
mg/l
0.55
15
141
5
35
1.38
0.38
1.2
1.1
—
—
—
0
0
55
469
1.13
0.36
1.1
1.1
1.2
0.3
u/ml
0.35
22
186
49
531
0.89
0.34
1.4
1.1
—
—
—
0
0
60
642
0.90
0.34
1.6
1.4
—
—
—
0
0
13
96
1.30
0.34
1.2
1.3
159.0
48.7
pmol/l
—
5
21
17
131
1.25
0.33
1.7
1.2
—
—
—
0
0
153
1566
0.94
0.33
3.3
2.8
0.7
0.8
ug/l
0.42
106
982
10
71
1.36
0.32
2.0
2.5
14.4
17.5
umol/l
—
10
71
87
769
1.09
0.32
1.2
1.2
—
—
—
0
0
23
261
0.85
0.29
1.2
1.6
—
1810.0
—
0
8
84
745
1.09
0.29
1.3
1.3
—
—
—
0
0
49
523
0.90
0.28
1.4
1.1
—
—
—
0
0
88
785
1.08
0.27
1.1
1.2
4.1
3.7
u/ml
0.06
30
251
16
126
1.22
0.27
3.2
1.7
—
—
—
0
0
16
126
1.22
0.27
3.2
1.7
—
—
—
0
0
16
126
1.22
0.27
3.2
1.7
—
—
—
0
0
184
1857
0.95
0.27
1.6
1.5
—
—
—
0
0
10
74
1.30
0.26
1.3
1.1
—
—
—
0
0
14
109
1.24
0.26
6.9
5.5
—
42.6
—
0
15
12
92
1.26
0.25
1.1
1.1
135.8
217.1
iu/ml
1.08
12
92
9
72
1.20
0.25
8.1
3.7
—
—
—
0
0
9
73
1.19
0.24
1.3
1.1
—
—
—
0
0
98
884
1.07
0.24
1.2
1.2
1.8
2.7
u/ml
0.41
57
521
9
74
1.17
0.24
1.3
1.1
—
—
—
0
0
10
75
1.28
0.24
1.0
1.0
—
—
—
0
0
10
75
1.28
0.24
1.3
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
6.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
5
41
1.17
0.21
1.2
1.1
—
—
—
0
0
39
413
0.91
0.21
1.5
1.5
—
—
—
0
0
8
99
0.78
0.21
1.1
1.2
—
1.5
nmol/l
—
0
15
91
825
1.06
0.20
1.8
1.6
—
—
—
0
0
10
77
1.25
0.20
1.3
1.1
—
—
—
0
0
53
472
1.08
0.19
1.3
1.2
—
—
—
0
0
85
772
1.06
0.19
1.4
1.5
—
—
—
0
0
60
539
1.07
0.18
1.1
1.1
3.2
7.6
u/ml
2.26
35
276
95
961
0.95
0.17
2.9
2.6
60.9
73.3
ml/min/173m2
1.79
40
346
18
151
1.15
0.17
1.8
2.4
1.6
2.0
mmol/l
—
10
121
6
74
0.78
0.15
1.2
1.2
—
—
—
0
0
114
1054
1.04
0.14
1.3
1.2
53.3
41.0
au/ml
—
5
43
12
99
1.17
0.13
1.3
1.4
541.4
46997.9
e6/l
—
5
59
49
443
1.07
0.13
1.1
1.1
—
—
—
0
0
25
219
1.10
0.13
2.2
2.1
—
—
—
0
0
9
104
0.83
0.13
1.3
1.2
—
—
—
0
0
19
166
1.10
0.11
1.9
2.3
—
—
—
0
0
20
176
1.09
0.10
2.9
1.8
—
—
—
0
0
5
43
1.12
0.10
1.2
1.1
—
—
—
0
0
12
102
1.13
0.09
1.1
1.1
—
40.7
—
0
6
12
103
1.12
0.08
1.1
1.2
—
69.1
—
0
10
5
61
0.79
0.08
2.4
2.4
—
—
—
0
0
20
178
1.08
0.08
3.1
3.2
0.9
0.8
nmol/l
0.31
13
143
20
179
1.08
0.07
1.7
1.4
—
—
—
0
0
22
198
1.07
0.07
1.5
1.4
8.9
11.5
mmol/l
—
7
34
20
180
1.07
0.06
1.7
1.4
—
—
—
0
0
20
180
1.07
0.06
1.7
1.4
—
—
—
0
0
11
96
1.10
0.05
1.0
1.2
—
4.2
—
0
5
20
181
1.06
0.05
1.7
1.4
—
—
—
0
0
20
181
1.06
0.05
1.7
1.4
—
—
—
0
0
32
321
0.96
0.05
1.2
1.4
3.1
14.0
u/ml
1.23
16
184
32
321
0.96
0.05
4.4
3.1
33.4
24.4
mg/l
0.72
24
199
11
97
1.09
0.04
1.2
1.0
0.9
1.0
u/l
—
5
46
11
97
1.09
0.04
1.5
1.5
—
—
—
0
0
28
259
1.04
0.03
1.0
1.0
3.3
3.3
kpa
0.09
22
213
20
183
1.05
0.03
1.7
1.4
—
—
—
0
0
93
908
0.98
0.03
1.5
1.6
—
—
—
0
0
50
492
0.98
0.03
2.5
1.8
—
—
—
0
0
13
117
1.07
0.03
2.1
2.3
—
—
—
0
0
28
262
1.03
0.01
1.0
1.0
-0.7
-1.1
mmol/l
—
5
43
28
262
1.03
0.01
1.0
1.0
7.3
7.2
kpa
0.22
22
216
67
652
0.99
0.01
1.4
1.4
—
—
—
0
0
56
544
0.99
0.00
2.7
1.9
—
—
—
0
0
35
338
1.00
0.00
1.5
1.2
—
—
—
0
0
11
104
1.02
0.00
1.0
1.1
—
—
—
0
0
13
122
1.03
0.00
1.1
1.3
—
—
u/ml
—
0
0
60
580
0.99
0.00
1.9
1.6
0.1
0.2
iu/ml
—
10
121
11
103
1.03
0.00
1.0
1.0
—
—
—
0
0
12
120
0.96
0.00
1.0
1.0
—
—
—
0
0
35
334
1.01
0.00
1.0
1.0
9.1
8.6
mu/l
0.10
29
286
7
72
0.94
0.00
1.0
1.1
3.8
3.9
u/ml
—
7
59
5
53
0.91
0.00
1.2
1.1
—
—
—
0
0
9
87
1.00
0.00
1.0
5.6
—
178.3
—
0
19
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
53
0.91
0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
8.0
—
0
8
Mortality – FinRegistry
↥Association
Association between endpoint E4_ENDODIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_ENDODIS | 2.214 [1.89, 2.6] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.06 |
During the follow-up period (1.1.1998 — 31.12.2019), 836 out of 14401 females with E4_ENDODIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_ENDODIS | 2.624 [2.25, 3.06] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 808 out of 12884 males with E4_ENDODIS died.
Mortality risk
Mortality risk for people of age
years, who have E4_ENDODIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.208% | 0.389% |
| 5 | 1.229% | 2.819% |
| 10 | 2.919% | 6.793% |
| 15 | 5.687% | 13.4% |
| 20 | 9.654% | 22.642% |
Relationships between endpoints
↥Index endpoint: E4_ENDODIS – Other endocrine disorders
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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