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Other endocrine disorders

DOID EFO Endpoint Browser PheWeb

E4_ENDODIS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E34, E35
  • Cause of death: ICD-10 — E34, E35

2 out of 7 registries used, show all original rules.

2085

4. Check minimum number of events

None

2085

5. Include endpoints

2201

6. Filter based on genotype QC (FinnGen only)

2089

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31129 16403 14689
Only index persons 22605 12208 10397
Unadjusted period prevalence (%)
Whole population 0.44 0.47 0.41
Only index persons 0.42 0.45 0.40
Median age at first event (years)
Whole population 7.81 8.09 7.35
Only index persons 10.77 11.10 10.40

-FinnGen-

Key figures

All Female Male
Number of individuals 2089 1249 840
Unadjusted period prevalence (%) 0.42 0.44 0.38
Median age at first event (years) 16.35 16.35 16.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2192
Matched controls
20988
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
21.5
307.7
384
205
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
+∞
307.7
591
*
H01AC01
ATC
somatropin; parenteral
592.2
307.7
319
6
E34.35
ICD-10 Finland
Abnormal growth retardation
1045.9
307.7
506
6
E34.0
ICD-10 Finland
Carcinoid syndrome
+∞
307.7
312
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
662.5
305.6
300
5
E34.30
ICD-10 Finland
Short stature NOS
+∞
232.0
222
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
214.9
206
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
47.9
173.3
105
22
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
163.1
157
*
H01CB02
ATC
octreotide; parenteral
373.9
145.4
147
*
130
Kela drug reimbursment
Malignant tumour
5.6
140.0
293
560
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
44.7
131.7
81
18
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
+∞
130.5
126
*
H02AB09
ATC
hydrocortisone; systemic
7.3
129.2
203
290
301
Kela drug reimbursment
Growth hormone
224.0
127.1
132
6
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
190.4
124.8
131
7
H01CB03
ATC
lanreotide; parenteral
317.1
121.5
124
*
E34.40
ICD-10 Finland
Constitutional tall stature
+∞
116.9
113
*
JFB00
NOMESCO Finland
Partial resection of small intestine
15.2
116.1
106
70
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
48.0
112.2
68
14
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
15.4
110.4
100
65
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
11.1
110.2
122
111
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
9.1
104.8
134
149
E34.31
ICD-10 Finland
Short stature, prenatal disorder
1022.7
103.4
102
*
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
499.3
99.7
100
*
E34.45
ICD-10 Finland
Abnormal growth increase
200.5
95.5
100
5
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.9
95.0
226
479
L01AX03
ATC
temozolomide; systemic
21.3
91.6
71
33
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
886.6
90.0
89
*
D77
ICPC
Malignant digestive neopl other/NOS
36.7
86.7
56
15
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.7
85.3
213
469
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
7.4
82.2
125
171
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
33.1
81.2
54
16
JN4CD
NOMESCO Finland
Very extensive body CT
6.8
76.9
125
184
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
74.0
843
4449
ZXE00
NOMESCO Finland
One hour or less
2.2
72.2
1012
5808
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
+∞
71.1
69
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
5.4
70.2
146
274
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
94.2
68.1
76
8
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
17.7
66.7
56
31
602
Kela drug reimbursment
Children's severe malnutrition
6.5
66.1
112
172
H03AA01
ATC
levothyroxine sodium; systemic
2.5
65.7
509
2244
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.4
63.5
248
751
JN4AD
NOMESCO Finland
Body CT examination
3.6
62.7
231
673
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
61.3
700
3642
25898
ICD-8 Finland
Polyglandular dysfunction and other diseases of endocrine glands, Alii definiti
+∞
60.7
59
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
59.9
452
1960
A11CC03
ATC
alfacalcidol; systemic
6.7
58.3
95
140
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
57.6
56
*
C17.2
ICD-10 Finland
Malignant neoplasm: Ileum
196.8
57.3
60
*
JN4BD
NOMESCO Finland
Extensive body CT
3.4
56.6
227
697
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
7.2
56.3
86
118
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
55.9
926
5516
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
12.2
55.4
57
46
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.8
54.5
301
1112
8240/3-C17.9
ICD-O-3
Neuroendocrine tumor, NOS, of small intestine, NOS
528.1
53.9
54
*
Z31.5
ICD-10 Finland
Genetic counselling
3.3
53.5
226
716
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
265.9
52.5
54
*
E34.3
ICD-10 Finland
Short stature, not elsewhere classified
+∞
51.4
50
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.6
51.3
184
525
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
5.7
51.1
98
170
25899
ICD-8 Finland
Polyglandular dysfunction and other diseases of endocrine glands, Other and unspecified diseases of endocrine system
+∞
50.4
49
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.1
50.3
148
368
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
49.6
573
2956
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
48.6
524
2628
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
48.5
226
758
SPAT1262
SPAT
Handing over of treatment supplies
2.5
47.9
360
1545
XX3DW
NOMESCO Finland
Time consuming IT work
2.9
45.6
228
795
E34.8
ICD-10 Finland
Other specified endocrine disorders
+∞
45.2
44
*
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
6.3
44.4
77
121
E30.09
ICD-10 Finland
Delayed puberty NOS
407.6
41.6
42
*
E30.00
ICD-10 Finland
Familial delayed puberty
209.9
41.3
43
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
8.0
41.0
57
70
A12AA04
ATC
calcium carbonate; oral
7.9
40.5
57
71
JN3AD
NOMESCO Finland
Abdominal CT examination
2.7
40.2
236
895
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.7
39.8
131
352
A04AA02
ATC
granisetron; systemic, transdermal
3.5
38.4
139
398
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.0
38.2
114
286
UJF32
NOMESCO Finland
Coloscopy
2.1
37.4
458
2385
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
37.3
525
2874
302
Kela drug reimbursment
Interferon alfa
+∞
37.0
36
*
JFB30
NOMESCO Finland
Right hemicolectomy
8.5
36.5
48
55
127
Kela drug reimbursment
Transplant complication
5.4
36.4
73
132
XX2RW, ,
NOMESCO Finland
9.0
36.4
46
50
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
35.4
526
2925
RD210, ,
NOMESCO Finland
3.6
35.4
123
343
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.1
34.6
74
142
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
5.9
34.2
63
105
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
33.9
848
5531
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.5
33.8
238
983
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.8
33.5
62
104
T73
ICPC
Neoplasm endocrine other/unspecified
170.2
33.2
35
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.0
32.9
412
2153
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
32.8
846
5553
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.4
32.8
253
1090
JN7AN
NOMESCO Finland
Somatostatin receptor isotope imaging
318.0
32.4
33
*
C10AC01
ATC
colestyramine; oral
4.6
32.3
78
166
121
Kela drug reimbursment
Severe hypofunction of sexual glands
6.3
32.2
55
85
R62.0
ICD-10 Finland
Delayed milestone
3.5
32.2
113
317
WX723
NOMESCO Finland
CPAP therapy
3.9
32.0
97
246
WVA30, ,
SPAT
3.2
30.9
127
394
JKA20
NOMESCO Finland
Cholecystectomy
5.5
30.7
60
106
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
30.4
302
1443
JN7SN
NOMESCO Finland
Somatostatin receptor SPECT
+∞
29.8
29
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.0
29.5
134
441
E83.50
ICD-10 Finland
Hypercalcemia
9.7
29.4
35
35
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
9.0
29.4
37
40
JN4SR
NOMESCO Finland
Very extensive PET-CT of receptors in whole body
293.4
29.4
30
*
E21.0
ICD-10 Finland
Primary hyperparathyroidism
80.2
29.2
33
*
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
80.2
29.2
33
*
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
7.8
29.1
41
51
L04AA06
ATC
mycophenolic acid; systemic
4.8
28.9
67
138
ZXD05
NOMESCO Finland
Urgent procedure
1.8
28.8
624
3869
L01BC06
ATC
capecitabine; oral
3.9
28.7
86
216
XFE00
NOMESCO Finland
Epicardial ultrasonography
5.0
28.6
63
124
J01MA12
ATC
levofloxacin; systemic
2.1
28.5
301
1471
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.9
28.5
145
508
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
6.5
28.5
47
70
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
283.1
28.3
29
*
C17.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of small intestine
283.1
28.3
29
*
NH3EA
NOMESCO Finland
Feet X-ray examination with load
5.1
28.3
61
118
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
28.0
418
2310
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
6.5
27.7
46
69
L03AB05
ATC
interferon alfa-2b; parenteral
37.8
27.5
35
9
E22.1
ICD-10 Finland
Hyperprolactinaemia
62.1
27.4
32
5
N02AA05
ATC
oxycodone; systemic
2.2
27.3
258
1207
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
140.6
27.2
29
*
H02AA02
ATC
fludrocortisone; oral
11.2
26.9
29
25
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
26.8
873
6015
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
26.7
243
1119
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
26.7
26
*
106
Kela drug reimbursment
Hypoparathyroidism
+∞
26.7
26
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
26.6
328
1696
BF20A, ,
NOMESCO Finland
262.6
26.3
27
*
C25.4
ICD-10 Finland
Malignant neoplasm: Endocrine pancreas
262.6
26.3
27
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.2
26.1
71
166
B03BA03
ATC
hydroxocobalamin; parenteral
3.4
26.1
99
292
L04AA01
ATC
[U] ciclosporin
6.5
26.1
43
64
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.8
25.6
59
121
T99
ICPC
Endocr/metab/nutrit disease other
5.5
24.9
49
87
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.9
24.8
75
190
WX780
NOMESCO Finland
Remote monitoring CPAP
3.4
24.8
91
263
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
5.4
24.6
49
88
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
5.2
24.4
51
96
E22.80
ICD-10 Finland
Central precocious puberty
242.2
24.3
25
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
24.0
419
2420
C03CA01
ATC
furosemide; systemic
1.8
23.5
383
2165
A02BC01
ATC
omeprazole; systemic
1.7
23.5
481
2910
ZXD00
NOMESCO Finland
Emergency procedure
3.8
23.5
74
193
7834C
ICD-9 Finland
Symptoms concerning nutrition, metabolism and development, Lack of expected normal physiological development[HÄIRIINTYNYT PITUUSKASVU]
65.3
23.4
27
*
Z94.0
ICD-10 Finland
Kidney transplant status
5.5
23.3
46
82
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
232.2
23.3
24
*
R50.9
ICD-10 Finland
Fever, unspecified
1.8
23.0
418
2441
104
Kela drug reimbursment
Thyroid insufficiency
2.7
22.3
126
466
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
22.2
243
1200
SPAT1377
SPAT
Polysomnography
3.5
22.0
77
216
R4190
NOMESCO Finland
Nutritional therapy
2.2
21.9
198
907
-50
ICPC
Medication/prescr/renewal
3.2
21.8
89
275
Z51.5
ICD-10 Finland
Palliative care
2.7
21.7
118
428
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
6.7
21.7
35
51
8249/3-C17.9
ICD-O-3
Neuroendocrine tumor, grade 2 of small intestine, NOS
+∞
21.5
21
*
JAH00
NOMESCO Finland
Laparotomy
3.6
21.4
73
201
Z3226
NOMESCO Finland
Physiotherapist
1.7
21.4
427
2558
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
7.3
20.9
31
41
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.0
20.9
45
87
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
20.7
173
767
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.6
20.5
68
184
8240/3-C17.2
ICD-O-3
Neuroendocrine tumor, NOS, of ileum
74.3
20.3
23
*
G02CB01
ATC
bromocriptine; systemic
5.1
20.3
43
82
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
202.9
20.2
21
*
E30.1
ICD-10 Finland
Precocious puberty
106.4
20.2
22
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.5
20.1
71
200
E34.1
ICD-10 Finland
Other hypersecretion of intestinal hormones
+∞
19.5
19
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.0
19.3
218
1087
WX402
NOMESCO Finland
General anaesthesia
1.7
19.3
479
3034
Z2445
NOMESCO Finland
Psychologist
2.1
19.2
189
895
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
19.2
737
5176
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.9
19.0
57
144
A41.9
ICD-10 Finland
Sepsis, unspecified
3.0
18.9
85
278
Z01.9
ICD-10 Finland
Special examination, unspecified
2.5
18.9
127
512
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
4.6
18.9
45
95
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
30.2
18.8
25
8
L04AX01
ATC
azathioprine; systemic
2.6
18.8
108
403
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
18.6
415
2554
B03XA01
ATC
erythropoietin; parenteral
6.2
18.6
32
50
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
7.1
18.5
28
38
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
+∞
18.5
18
*
E34.5
ICD-10 Finland
Androgen resistance syndrome
+∞
18.5
18
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
18.3
165
755
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
18.3
246
1303
XX9AD
NOMESCO Finland
Complementary CT
183.4
18.2
19
*
A55
ICPC
General and Unspecified, Local injection/infiltration
6.3
18.1
31
48
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
6.7
18.1
29
42
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
5.8
18.0
33
55
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
18.0
161
735
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.9
17.9
88
303
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
7.8
17.8
25
31
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.1
17.7
74
232
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
5.7
17.6
33
56
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
17.6
332
1949
WZC30
NOMESCO Finland
Teaching
1.8
17.5
274
1523
102
Kela drug reimbursment
Diabetes insipidus
+∞
17.4
17
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
17.4
17
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.1
17.4
48
114
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
17.3
168
791
E26.0
ICD-10 Finland
Primary hyperaldosteronism
91.8
17.3
19
*
JLC10
NOMESCO Finland
Distal pancreatectomy
35.5
17.2
22
6
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.4
17.2
121
498
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
16.8
212
1097
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
16.7
495
3259
RL140, ,
NOMESCO Finland
4.7
16.7
39
81
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2.8
16.5
83
289
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
5.7
16.4
31
53
ZXA10
NOMESCO Finland
Bilateral
1.7
16.4
360
2198
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.7
16.4
87
312
8246/3-C17.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of small intestine, NOS
+∞
16.4
16
*
N18.8
ICD-10 Finland
Other chronic renal failure
4.0
16.4
47
115
B81
ICPC
Anaemia vit B12/folate deficiency
3.2
16.2
64
194
Z2446
NOMESCO Finland
Social worker
1.8
16.2
248
1367
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.0
16.1
182
906
A79
ICPC
Malignancy NOS
5.2
16.1
33
61
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
15.7
16.1
26
16
XF404
NOMESCO Finland
Ambulatory ECG
2.1
16.0
166
801
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
12.9
16.0
28
21
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
38.6
16.0
20
5
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
15.9
168
816
P05.1
ICD-10 Finland
Small for gestational age
5.8
15.9
29
48
R11
ICD-10 Finland
Nausea and vomiting
1.9
15.9
227
1224
UDC00
NOMESCO Finland
Ear microscopy
2.0
15.8
180
899
UKC02
NOMESCO Finland
Cystoscopy
1.9
15.8
218
1162
L04AD01
ATC
ciclosporin; systemic
3.3
15.8
59
173
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
15.7
143
657
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
6.1
15.4
27
43
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.9
15.3
72
242
107
Kela drug reimbursment
Pernicious anaemia
5.0
15.3
33
64
C17.0
ICD-10 Finland
Malignant neoplasm: Duodenum
82.1
15.3
17
*
205
Kela drug reimbursment
Chronic hypertension
1.7
15.2
308
1839
D76
ICPC
Malignant neoplasm pancreas
21.3
15.2
22
10
N06AA09
ATC
amitriptyline; systemic
2.2
15.1
135
615
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.5
15.1
51
140
JAH01
NOMESCO Finland
Laparoscopy
2.6
15.0
91
350
-44
ICPC
Preventive immunization/medic
2.1
15.0
153
735
T10
ICPC
Growth delay
5.5
15.0
29
51
OAB50, ,
SPAT
2.4
14.8
101
410
E28.3
ICD-10 Finland
Primary ovarian failure
43.4
14.8
18
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
14.7
453
2999
XKC03
NOMESCO Finland
Water cystometry
3.3
14.6
56
167
SPAT1312
SPAT
General health counselling
1.5
14.6
779
5776
E29.1
ICD-10 Finland
Testicular hypofunction
6.4
14.5
24
36
XA800
NOMESCO Finland
Neuropsychological investigation
2.1
14.4
134
621
C18.99
ICD-10 Finland
Malignant tumor in unspecified location in the colon other or unspecified histology
24.1
14.4
20
8
N04BC06
ATC
cabergoline; oral
17.7
14.3
22
12
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.6
14.2
34
72
340
Kela drug reimbursment
Everolimus
144.6
14.2
15
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
14.1
414
2710
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
14.1
128
588
F83
ICD-10 Finland
Mixed specific developmental disorders
2.7
14.0
76
276
C03DA01
ATC
spironolactone; oral
1.9
14.0
172
882
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
14.0
339
2119
137
Kela drug reimbursment
Uraemia requiring dialysis
5.0
14.0
30
58
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.8
13.9
69
239
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
5.3
13.9
28
51
R68.8
ICD-10 Finland
Other specified general symptoms and signs
4.7
13.8
32
66
158
Kela drug reimbursment
Everolimus
41.0
13.8
17
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
13.7
221
1235
OAB72
NOMESCO Finland
Weight control and weight loss guidance
5.2
13.6
28
52
K06.18
ICD-10 Finland
Another gingival hyperplasia
5.2
13.6
28
52
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.8
13.6
68
237
JN4DD
NOMESCO Finland
Scout CT scan of torso
28.9
13.6
18
6
L04AD02
ATC
tacrolimus; systemic
3.9
13.6
40
100
KH1AD
NOMESCO Finland
CT of urinary organs
3.0
13.5
60
196
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.5
13.5
82
316
2594A
ICD-9 Finland
Other endocrine disorders, Dwarfism, not elsewhere classified
+∞
13.3
13
*
E23.6
ICD-10 Finland
Other disorders of pituitary gland
+∞
13.3
13
*
BB1BQ
NOMESCO Finland
Extensive scintigraphy of parathyroid gland, 2 isotopes, SPECT and low-dose CT
+∞
13.3
13
*
XF602
NOMESCO Finland
Bloodpressure monitoring
3.9
13.3
39
97
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.7
13.2
69
246
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.8
13.2
30
61
TK800
NOMESCO Finland
Hemodialysis
3.7
13.1
41
107
WZA10
NOMESCO Finland
Extensive medical or dental certificate
3.7
13.1
41
107
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
3.4
13.1
46
130
H02AB06
ATC
prednisolone; systemic
1.4
13.0
777
5851
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.0
13.0
58
190
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
4.5
12.9
31
66
C18.19
ICD-10 Finland
Malignant tumor in appendix other or unspecified histology
38.5
12.9
16
*
XX4AW, ,
NOMESCO Finland
3.4
12.8
46
132
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
12.8
198
1094
A06AD11
ATC
lactulose; oral
1.8
12.8
201
1116
SPAT1153
SPAT
Removal of sutures
1.5
12.7
473
3250
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.7
12.7
40
105
321
Kela drug reimbursment
Paricalcitol and cinacalcet
27.3
12.7
17
6
C18.09
ICD-10 Finland
Malignant tumor of caecum other or unspecified histology
27.3
12.7
17
6
YHMAS, ,
NOMESCO Finland
5.8
12.6
23
38
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
12.6
183
990
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
12.6
153
781
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
48.2
12.6
15
*
E27.0
ICD-10 Finland
Other adrenocortical overactivity
48.2
12.6
15
*
C17.1
ICD-10 Finland
Malignant neoplasm: Jejunum
48.2
12.6
15
*
A02BA02
ATC
ranitidine; systemic
1.7
12.5
244
1439
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.5
12.5
77
299
ZY010
NOMESCO Finland
Hospital outpatient
1.8
12.5
177
952
SPAT1325
SPAT
Vaccination
1.4
12.4
723
5407
Z3231
NOMESCO Finland
Registered nurse
1.4
12.4
593
4278
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
4.9
12.4
27
53
AA1AD
NOMESCO Finland
CT of head and brain
1.6
12.4
370
2426
A12AA06
ATC
calcium lactate gluconate; oral
67.3
12.4
14
*
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
67.3
12.4
14
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
12.3
82
330
2592A
ICD-9 Finland
Other endocrine disorders, Carcinoid syndrome
+∞
12.3
12
*
E25.01
ICD-10 Finland
Congenital adrenal hyperplasia
+∞
12.3
12
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
12.3
143
720
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
125.2
12.2
13
*
318
Kela drug reimbursment
Teriparatide
125.2
12.2
13
*
SPAT1281
SPAT
Other administrative function
1.8
12.2
185
1015
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
5.0
12.2
26
50
H05BX01
ATC
cinacalcet; oral
23.4
12.2
17
7
R4180
NOMESCO Finland
Podiatric therapy
4.7
12.1
28
58
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.2
12.0
32
74
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
12.0
129
632
SPAT1260
SPAT
Consultation of another employee
1.6
11.9
335
2164
B01AB10
ATC
tinzaparin; parenteral
1.9
11.9
148
763
K65.0
ICD-10 Finland
Acute peritonitis
5.3
11.9
24
44
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
11.8
808
6200
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
4.6
11.8
28
59
SPAT1301
SPAT
No procedures
1.4
11.7
613
4493
G47.3
ICD-10 Finland
Sleep apnoea
1.6
11.6
303
1922
C08CA02
ATC
felodipine; oral
2.1
11.6
113
533
JF1BD
NOMESCO Finland
Very extensive small bowel CT
9.7
11.6
23
23
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.7
11.6
27
56
N06AX16
ATC
venlafaxine; oral
1.6
11.6
257
1567
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.7
11.6
63
230
SPAT1263
SPAT
Sampling
1.4
11.5
843
6534
Z50.0
ICD-10 Finland
Cardiac rehabilitation
5.8
11.4
21
35
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
5.3
11.4
23
42
BCA30
NOMESCO Finland
Unilateral adrenalectomy
28.9
11.4
15
5
E23.2
ICD-10 Finland
Diabetes insipidus
62.5
11.4
13
*
C25.2
ICD-10 Finland
Malignant neoplasm: Tail of pancreas
18.2
11.3
17
9
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
+∞
11.3
11
*
E30.8
ICD-10 Finland
Other disorders of puberty
+∞
11.3
11
*
8249/3-C25.9
ICD-O-3
Neuroendocrine tumor, grade 2 of pancreas, NOS
+∞
11.3
11
*
E340, C179,
ICD-10 Finland
+∞
11.3
11
*
E27.5
ICD-10 Finland
Adrenomedullary hyperfunction
+∞
11.3
11
*
E35.8
ICD-10 Finland
Disorders of other endocrine glands in diseases classified elsewhere
+∞
11.3
11
*
E21.1
ICD-10 Finland
Secondary hyperparathyroidism, not elsewhere classified
115.5
11.2
12
*
8249/3-C17.2
ICD-O-3
Neuroendocrine tumor, grade 2 of ileum
115.5
11.2
12
*
A02BC05
ATC
esomeprazole; systemic
1.4
11.2
599
4397
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.0
11.2
131
661
C07AB02
ATC
metoprolol; systemic
1.6
11.2
248
1512
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.3
11.1
85
364
E0000UV, ,
ATC
1.4
11.1
881
6909
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
11.1
264
1639
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.8
11.1
54
186
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
11.0
128
644
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
10.9
141
735
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
10.9
287
1823
TJD20
NOMESCO Finland
Change of gastrostomy tube
4.3
10.9
28
63
N02AX02
ATC
tramadol; systemic, rectal
1.4
10.9
597
4398
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
10.9
107
507
ZX120
NOMESCO Finland
Intravenous
1.8
10.9
170
942
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.4
10.7
74
303
Q87.19
ICD-10 Finland
Congenital malformation syndromes predominantly associated with short stature
41.7
10.7
13
*
KAC00
NOMESCO Finland
Nephrectomy
5.7
10.7
20
34
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
8.9
10.7
22
24
A50
ICPC
General and Unspecified, Medication/prescr/renewal
2.5
10.6
67
263
B03XA02
ATC
darbepoetin alfa; parenteral
3.6
10.6
35
95
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.0
10.6
110
532
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
4.9
10.6
23
45
N05BA04
ATC
oxazepam; oral
1.5
10.6
411
2840
R06.0
ICD-10 Finland
Dyspnoea
1.5
10.6
414
2865
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.8
10.5
157
857
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.9
10.4
143
761
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
2.7
10.4
55
198
E87.6
ICD-10 Finland
Hypokalaemia
2.7
10.4
56
204
L02AE02
ATC
leuprorelin; implant, parenteral
2.6
10.4
61
232
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
10.3
224
1358
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
10.3
187
1081
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
10.3
1505
12906
H05AA02
ATC
teriparatide; parenteral
105.8
10.2
11
*
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
10.2
151
822
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
10.2
89
403
N91.0
ICD-10 Finland
Primary amenorrhoea
9.7
10.2
20
20
E03
ICD-10 Finland
Other hypothyroidism
2.1
10.2
96
448
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
3.7
10.2
32
84
B01AB05
ATC
enoxaparin; parenteral
1.5
10.1
421
2944
V03AG01
ATC
sodium cellulose phosphate; systemic
4.9
10.1
22
43
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
4.0
10.1
28
67
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
4.7
10.1
23
47
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
2.0
10.1
102
489
A06AH03
ATC
naloxegol; oral
4.3
10.1
26
59
Z56.5
ICD-10 Finland
Uncongenial work
18.1
10.0
15
8
XKD00
NOMESCO Finland
Uroflowmetry
1.7
10.0
186
1084
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.1
9.9
97
459
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
9.9
67
272
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
4.0
9.9
28
68
K85
ICD-10 Finland
Acute pancreatitis
4.0
9.9
28
68
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
4.8
9.9
22
44
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
3.0
9.9
42
134
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
9.9
254
1605
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.7
9.9
191
1124
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
3.4
9.8
35
100
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
4.5
9.8
24
52
L01BA01
ATC
methotrexate; systemic
2.5
9.8
62
244
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
9.8
207
1246
FM2CE, ,
NOMESCO Finland
2.1
9.8
89
410
BC00A, ,
NOMESCO Finland
10.9
9.8
18
16
8240/3-C34.9
ICD-O-3
Neuroendocrine tumor, NOS, of lung, NOS
38.4
9.8
12
*
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
8.1
9.7
21
25
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.6
9.6
55
206
XX9TE
NOMESCO Finland
Compementary ultrasound examination
5.4
9.6
19
34
A07AA02
ATC
nystatin; oral
2.1
9.6
90
419
Q87.14
ICD-10 Finland
Noonan's syndrome
25.0
9.6
13
5
ZXF10
NOMESCO Finland
Interruption caused by technical failure of equipment
19.3
9.6
14
7
H02AB04
ATC
methylprednisolone; systemic
1.7
9.6
202
1216
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.5
9.5
59
230
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
2.1
9.5
92
434
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
8.4
9.5
20
23
E23.05
ICD-10 Finland
Lack of TSH
52.9
9.5
11
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
9.2
9.5
19
20
WX610
NOMESCO Finland
Patient controlled analgesia
4.6
9.4
22
46
WF049
NOMESCO Finland
Radiotherapy of metastasis
2.7
9.4
48
170
-56
ICPC
Dressing/pressure/compress/tamponade
3.2
9.4
36
108
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
5.2
9.3
19
35
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.6
9.3
52
193
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
9.3
355
2440
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
9.3
267
1730
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.5
9.3
363
2507
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
9.3
151
847
8240/3-C20.9
ICD-O-3
Neuroendocrine tumor, NOS, of rectum, NOS
96.2
9.2
10
*
E21.2
ICD-10 Finland
Other hyperparathyroidism
96.2
9.2
10
*
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
96.2
9.2
10
*
E23.03
ICD-10 Finland
Lack of ACTH
96.2
9.2
10
*
2520A
ICD-9 Finland
Disorders of parathyroid gland, Hyperparathyroidism
+∞
9.2
9
*
E20.8
ICD-10 Finland
Other hypoparathyroidism
+∞
9.2
9
*
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
+∞
9.2
9
*
8249/3-C80.9
ICD-O-3
Neuroendocrine tumor, grade 2 of unknown primary site
+∞
9.2
9
*
T90
ICPC
Diabetes non-insulin dependent
1.5
9.2
271
1765
S02.51
ICD-10 Finland
Fracture of tooth, open
1.7
9.2
155
878
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
9.2
127
678
197
Kela drug reimbursment
Sunitinib
16.9
9.2
14
8
SPAT1139
SPAT
Nutrition survey
2.4
9.1
62
253
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.4
9.1
63
259
SPAT1255
SPAT
Intravenous administration of medicine
2.0
9.1
95
462
H52.0
ICD-10 Finland
Hypermetropia
2.2
9.0
74
327
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.0
889
7134
L01CB01
ATC
etoposide; systemic
7.7
9.0
20
25
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
9.0
153
868
H50.31
ICD-10 Finland
Intermittent exotropia
2.8
9.0
44
152
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.1
9.0
82
378
-54
ICPC
Repair/fix-suture/cast/prosth device
3.0
9.0
39
126
A02BC02
ATC
pantoprazole; systemic
1.3
9.0
1018
8330
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
9.0
169
987
SPAT1298
SPAT
Other function in accordance with nutritional therapy nomenclature
3.8
8.9
27
69
SPAT1094
SPAT
Continuous Positive Airway Pressure
4.4
8.9
22
48
C18.90
ICD-10 Finland
Malignant tumor in unspecified location in the colon without histology
13.1
8.9
15
11
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
2.6
8.9
50
186
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.0
8.9
102
512
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
8.9
115
601
WW500
NOMESCO Finland
Blood transfusion
2.1
8.9
79
361
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
8.9
201
1231
8240/3-C18.2
ICD-O-3
Neuroendocrine tumor, NOS, of ascending colon
35.3
8.8
11
*
D44.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Endocrine gland, unspecified
35.3
8.8
11
*
SAA04
NOMESCO Finland
Special examination of mouth
1.7
8.8
169
992
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
5.0
8.8
19
37
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.8
8.8
138
766
R55
ICD-10 Finland
Syncope and collapse
1.7
8.8
171
1008
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
4.7
8.7
20
41
SPAT1324
SPAT
Screening procedure
0.5
8.7
93
1641
A11CC02
ATC
dihydrotachysterol; oral
23.1
8.7
12
5
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.3
8.7
65
277
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
1.8
8.6
134
741
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
12.0
8.6
15
12
K29.4
ICD-10 Finland
Chronic atrophic gastritis
3.5
8.6
29
80
SPAT1238
SPAT
Brief therapy
2.6
8.6
48
178
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
8.6
51
195
E86
ICD-10 Finland
Volume depletion
2.8
8.6
41
140
R63.4
ICD-10 Finland
Abnormal weight loss
2.2
8.6
70
309
B05DB
ATC
Hypertonic solutions
4.8
8.5
19
38
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
8.5
357
2494
8240/3-C25.9
ICD-O-3
Neuroendocrine tumor, NOS, of pancreas, NOS
48.1
8.5
10
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.2
8.5
68
298
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
8.5
155
898
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
3.1
8.5
35
110
H03BB01
ATC
carbimazole; oral
2.2
8.5
66
286
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
8.3
296
2003
D13.7
ICD-10 Finland
Benign neoplasm: Endocrine pancreas
26.4
8.3
11
*
N06AX21
ATC
duloxetine; oral
1.6
8.3
177
1069
B05DA
ATC
Isotonic solutions
4.3
8.3
21
47
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
9.6
8.3
16
16
SCA02
NOMESCO Finland
Preventive oral health care
1.4
8.3
430
3122
8240/3-C16.9
ICD-O-3
Neuroendocrine tumor, NOS, of stomach, NOS
86.6
8.3
9
*
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
86.6
8.3
9
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
86.6
8.3
9
*
K03.66
ICD-10 Finland
Tooth plaque
1.6
8.3
218
1385
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
6.7
8.2
20
29
T29
ICPC
Endocr/metab/nutr sympt/compl other
3.1
8.2
34
107
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
3.5
8.2
28
78
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
8.2
8
*
L01EG02
ATC
everolimus; oral
+∞
8.2
8
*
E20.0
ICD-10 Finland
Idiopathic hypoparathyroidism
+∞
8.2
8
*
E21.5
ICD-10 Finland
Disorder of parathyroid gland, unspecified
+∞
8.2
8
*
E20.1
ICD-10 Finland
Pseudohypoparathyroidism
+∞
8.2
8
*
1CB02, ,
NOMESCO Finland
+∞
8.2
8
*
S55
ICPC
Skin, Local injection/infiltration
12.3
8.1
14
11
I15.8
ICD-10 Finland
Other secondary hypertension
4.8
8.1
18
36
SPAT1104
SPAT
Monitoring of emergency patient
1.9
8.0
105
552
A03FA02
ATC
cisapride; oral, rectal
1.9
8.0
107
566
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
8.0
171
1034
H02AB02
ATC
dexamethasone; systemic
1.7
7.9
150
878
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.3
7.9
56
233
L01XE10
ATC
[U] everolimus
32.0
7.9
10
*
D35.31
ICD-10 Finland
Cyst in Rathke's pocket
32.0
7.9
10
*
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.2
7.9
63
276
H65.3
ICD-10 Finland
Chronic mucoid otitis media
1.8
7.9
125
696
WX002
NOMESCO Finland
Sedation and analgesia
1.5
7.9
282
1911
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
7.9
227
1471
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
2.3
7.9
60
258
XLA10, ,
NOMESCO Finland
2.3
7.8
57
240
V03AE01
ATC
polystyrene sulfonate; oral
4.3
7.8
20
45
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
7.8
7.8
17
21
A04AA01
ATC
ondansetron; systemic, rectal
1.7
7.8
136
778
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
3.4
7.8
27
76
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.6
7.8
43
159
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
7.8
646
5035
Y0099
ICD-8 Finland
Investigation of endocrine system and metabolism
9.6
7.8
15
15
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.5
7.8
46
176
ZX070
NOMESCO Finland
Intensity modified radiotherapy
3.3
7.8
28
81
K92.1
ICD-10 Finland
Melaena
2.0
7.7
77
368
N06AB04
ATC
citalopram; systemic
1.5
7.7
285
1942
HAHOM, ,
NOMESCO Finland
2.8
7.7
37
127
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
6.0
7.7
20
32
5AB14, ,
NOMESCO Finland
6.9
7.7
18
25
E83.51
ICD-10 Finland
Hypocalcemia
6.9
7.7
18
25
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
3.7
7.7
24
63
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.3
7.6
57
243
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
7.6
328
2301
SPAT1110
SPAT
Measurement of pain intensity
4.6
7.6
18
38
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.9
7.6
101
533
XF600
NOMESCO Finland
Bloodpressure measurement
1.6
7.6
156
933
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.1
7.6
67
306
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
2.8
7.6
36
123
JN5SR
NOMESCO Finland
Very extensive PET-CT of receptors in upper body
43.2
7.6
9
*
M05BX04
ATC
denosumab; parenteral
2.2
7.6
65
294
J94.8
ICD-10 Finland
Other specified pleural conditions
3.9
7.5
22
55
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
6.7
7.5
18
26
IGY99
NOMESCO Finland
Other psychiatric treatment contact
1.8
7.5
102
543
WX730
NOMESCO Finland
Conventional respirator
3.0
7.5
32
103
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.1
7.5
31
98
RL130, ,
NOMESCO Finland
3.1
7.5
30
93
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
7.1
7.4
17
23
JJA20
NOMESCO Finland
Open biopsy of liver
7.1
7.4
17
23
C74.9
ICD-10 Finland
Malignant neoplasm: Adrenal gland, unspecified
24.0
7.4
10
*
Z49.2
ICD-10 Finland
Other dialysis
4.3
7.4
19
43
L68.0
ICD-10 Finland
Hirsutism
4.4
7.4
18
39
T81.2
ICD-10 Finland
Accidental puncture and laceration during a procedure, not elsewhere classified
4.4
7.4
18
39
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.3
7.4
27
79
R03AC02
ATC
salbutamol; inhalant
1.3
7.4
1096
9206
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.4
420
3091
SPAT1310
SPAT
Counselling related to known health issue
1.3
7.3
629
4918
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
7.3
1112
9360
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
6.4
7.3
18
27
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.7
7.3
37
131
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
3.4
7.3
25
70
A01AB09
ATC
miconazole; local oral
1.7
7.3
140
823
8246/3-C80.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of unknown primary site
76.9
7.3
8
*
E21
ICD-10 Finland
Hyperparathyroidism and other disorders of parathyroid gland
76.9
7.3
8
*
E35.0
ICD-10 Finland
Disorders of thyroid gland in diseases classified elsewhere
76.9
7.3
8
*
E26.9
ICD-10 Finland
Hyperaldosteronism, unspecified
76.9
7.3
8
*
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
3.6
7.3
23
61
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.3
7.3
54
230
N05BA01
ATC
diazepam; systemic, rectal
1.6
7.2
186
1175
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
3.2
7.2
28
85
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
6.8
7.2
17
24
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
12.8
7.2
12
9
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
7.2
157
954
WX204
NOMESCO Finland
Axillary plexus blockaced
2.3
7.2
50
207
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.3
7.2
533
4082
J01MA02
ATC
ciprofloxacin; systemic
1.3
7.2
517
3942
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
4.5
7.2
17
36
BB1AN
NOMESCO Finland
Parathyroid gland isotope imaging, 1 isotope
+∞
7.2
7
*
E34.4
ICD-10 Finland
Constitutional tall stature
+∞
7.2
7
*
E22.9
ICD-10 Finland
Hyperfunction of pituitary gland, unspecified
+∞
7.2
7
*
E35.1
ICD-10 Finland
Disorders of adrenal glands in diseases classified elsewhere
+∞
7.2
7
*
E23.1
ICD-10 Finland
Drug-induced hypopituitarism
+∞
7.2
7
*
E23.08
ICD-10 Finland
Hypopituitarism
+∞
7.2
7
*
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
2.9
7.2
33
111
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
6.2
7.1
18
28
TJF80
NOMESCO Finland
Ostomy education
3.3
7.1
26
76
JFB20
NOMESCO Finland
Ileocaecal resection
5.7
7.1
19
32
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
10.4
7.1
13
12
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
9.0
7.1
14
15
F50.1
ICD-10 Finland
Atypical anorexia nervosa
3.5
7.0
24
67
TPX15
NOMESCO Finland
Removal of vascular injection port
6.6
7.0
17
25
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
2.7
7.0
37
134
C05AA08
ATC
fluocortolone; rectal, topical
1.6
7.0
160
983
K56.7
ICD-10 Finland
Ileus, unspecified
3.4
7.0
25
72
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
2.2
7.0
55
240
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
3.3
7.0
26
77
T50
ICPC
Metabolic, Medication/prescr/renewal
19.2
7.0
10
5
WZC15, ,
NOMESCO Finland
7.0
6.9
16
22
N03AX09
ATC
lamotrigine; oral
1.8
6.9
103
564
A10AE04
ATC
insulin glargine; parenteral
1.7
6.9
126
731
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.4
6.9
45
181
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.3
6.9
50
211
AQ2
HP
Electrophysiological electroanatomical examination
11.5
6.9
12
10
I15.9
ICD-10 Finland
Secondary hypertension, unspecified
3.9
6.9
20
50
HA1AA
NOMESCO Finland
X-ray mammography
1.8
6.9
92
488
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.0
6.9
74
365
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
8.4
6.8
14
16
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.6
6.8
37
136
S50
ICPC
Skin, Medication/prescr/renewal
5.8
6.8
18
30
Z51.88
ICD-10 Finland
Other specified medical care
2.7
6.8
34
120
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.4
6.7
44
177
Z3229
NOMESCO Finland
Other healthcare associate professional
1.6
6.7
164
1023
C08CA01
ATC
amlodipine; oral
1.4
6.7
418
3114
RT160, ,
NOMESCO Finland
3.3
6.7
25
74
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.6
6.7
155
955
F50.0
ICD-10 Finland
Anorexia nervosa
2.8
6.7
32
110
ZX112
NOMESCO Finland
Subcutaneous
2.4
6.7
43
172
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
2.3
6.7
50
214
UJF92
NOMESCO Finland
Capsular endoscopy
2.3
6.7
50
214
A12BA01
ATC
potassium chloride; oral
2.4
6.7
44
178
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
7.2
6.7
15
20
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
38.4
6.6
8
*
C80.98
ICD-10 Finland
Malignant tumor without specified localization other specified histology
38.4
6.6
8
*
4AA09, ,
NOMESCO Finland
7.9
6.6
14
17
JJB10
NOMESCO Finland
Atypcal resection of liver
10.5
6.6
12
11
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
1.7
6.6
117
674
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
6.6
204
1342
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
2.3
6.6
48
203
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
6.6
565
4408
62
HP
Catheterization and pressure measurement of the right side of the heart
8.9
6.6
13
14
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
6.6
144
876
N03AX16
ATC
[U] pregabalin
1.4
6.6
294
2075
L03AA04, ,
ATC
16.0
6.6
10
6
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.6
6.6
146
892
B01AA03
ATC
warfarin; systemic
1.5
6.5
189
1227
R4110
NOMESCO Finland
Physiotherapy
1.3
6.5
472
3597
R51.80
ICD-10 Finland
Headache
1.4
6.5
331
2390
RS220, ,
NOMESCO Finland
2.5
6.5
40
157
K02
ICD-10 Finland
Dental caries
1.7
6.5
122
715
WX882
NOMESCO Finland
High dependency care
1.7
6.4
114
657
SPAT1254
SPAT
Administration of medicine
1.4
6.4
321
2312
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
6.4
79
409
C02CA01
ATC
prazosin; oral
3.9
6.4
18
44
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.0
6.4
67
328
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.5
6.4
206
1368
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.6
6.3
35
130
SPAT1229
SPAT
Assessment of need for aid
1.8
6.3
87
466
C26.0
ICD-10 Finland
Malignant neoplasm: Intestinal tract, part unspecified
67.1
6.3
7
*
1522B
ICD-9 Finland
Malignant neoplasm of small intestine, including duodenum, Ileum[NEOPLASMA MALIGNUM ILEI,ALIA DEFINITA SEU NUD]
67.1
6.3
7
*
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.8
6.3
30
103
-51
ICPC
I&d/flush/aspiration
3.7
6.3
19
49
E03.89
ICD-10 Finland
Other specified hypothyroidism
2.1
6.2
55
252
SPAT1211
SPAT
Application of soft bandage
1.5
6.2
185
1207
R03BA05
ATC
fluticasone; inhalant
1.3
6.2
383
2847
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
2.5
6.2
36
137
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.2
6.2
50
221
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
5.1
6.2
18
34
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
6.2
332
2416
TAB24
NOMESCO Finland
Implantation of epidural injection gate
+∞
6.1
6
*
E34.2
ICD-10 Finland
Ectopic hormone secretion, not elsewhere classified
+∞
6.1
6
*
E27.2
ICD-10 Finland
Addisonian crisis
+∞
6.1
6
*
8246/3-C25.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of pancreas, NOS
+∞
6.1
6
*
2533A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Pituitary dwarfism[NANISMUS HYPOPHYSARIUS]
+∞
6.1
6
*
F50.9
ICD-10 Finland
Eating disorder, unspecified
2.3
6.1
44
185
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
1.9
6.1
69
346
XJC10
NOMESCO Finland
Oesophageal pH monitoring
3.4
6.1
21
59
E000003, ,
ATC
1.8
6.1
91
499
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
17.3
6.1
9
5
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
17.3
6.1
9
5
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.8
6.1
84
450
322
Kela drug reimbursment
Sunitinib
25.6
6.1
8
*
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
4.2
6.1
16
37
JN6AD
NOMESCO Finland
CT of torso and neck
3.1
6.1
25
79
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
2.5
6.1
35
133
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
5.7
6.1
16
27
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
6.0
126
758
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
1.9
6.0
69
348
WVA20
NOMESCO Finland
Medicine administration
2.2
6.0
50
224
T78.4
ICD-10 Finland
Allergy, unspecified
1.7
6.0
105
603
6BA02, ,
NOMESCO Finland
3.8
6.0
18
46

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
451
994
5.21
185.94
6.3
3.6
1.22
1.23
mmol/l
0.74
412
855
566
1554
4.35
176.99
2.9
2.1
313.98
366.55
nmol/l
6.47
542
1438
207
251
8.62
151.96
1.8
1.5
—
—
—
0
0
501
1426
4.06
146.92
4.4
3.5
—
—
—
0
0
299
669
4.80
118.58
2.3
1.5
6.52
7.02
u/l
0.29
201
476
184
296
6.41
104.35
4.5
4.8
2.64
2.17
mmol/l
1.12
142
176
588
2326
2.94
98.29
11.2
8.1
1.20
1.20
mmol/l
0.10
557
2202
817
3910
2.60
93.43
6.2
3.5
7.40
7.40
ph
0.48
402
705
906
4578
2.53
92.09
4.6
3.1
2.36
2.36
mmol/l
0.05
849
4074
1359
8275
2.51
91.60
17.6
9.5
0.00
0.00
e9/l
0.55
1173
6590
297
838
3.77
85.47
2.3
1.5
11.84
19.48
iu/l
4.82
213
642
173
324
5.46
83.52
3.9
3.9
—
—
—
0
0
129
208
6.25
72.67
4.6
4.3
—
—
—
0
0
167
353
4.82
70.03
3.7
3.6
56.28
54.65
%
0.75
167
353
1150
7056
2.18
68.09
12.9
8.0
1.23
1.22
mmol/l
3.72
1077
6554
1758
12896
2.54
66.36
5.7
3.7
14.86
14.56
pmol/l
4.97
1631
11748
144
286
5.09
64.89
2.9
2.5
16.72
16.84
%
0.09
75
169
1197
7602
2.12
63.03
12.5
7.9
1.22
1.22
mmol/l
0.96
833
6693
320
1136
2.99
62.76
4.2
4.2
0.46
0.55
%
0.43
96
372
314
1121
2.96
60.88
4.6
4.6
0.10
0.38
%
0.45
86
303
285
965
3.10
60.62
3.4
3.3
4.61
4.73
pmol/l
0.73
255
860
384
1560
2.65
58.08
3.4
3.3
0.21
0.21
g/l
0.09
368
1487
319
1179
2.86
57.91
4.6
4.5
0.06
0.10
%
0.52
94
368
639
3271
2.23
57.66
3.8
2.8
529.39
562.98
mosm/kgh2o
2.85
579
2813
328
1237
2.81
57.30
4.6
4.5
0.73
0.91
%
0.56
103
425
1548
11115
2.14
55.38
11.6
6.6
100.63
88.74
u/l
9.36
1476
10454
443
2002
2.40
53.06
3.6
2.5
21.25
22.44
%
1.08
395
1780
1036
6509
1.99
52.96
4.2
2.5
74.54
72.93
nmol/l
1.12
968
5985
1240
8301
1.99
52.67
10.3
7.2
0.65
0.65
%
0.01
1199
7841
975
6007
2.00
52.62
8.4
5.5
36.27
36.47
g/l
0.56
895
5626
1264
8561
1.98
51.38
10.3
7.1
3.08
2.96
%
0.97
1223
8082
276
1008
2.86
50.92
3.0
1.9
9.46
12.17
nmol/l
5.15
242
888
1267
8619
1.97
50.47
10.6
7.3
8.64
8.34
%
3.09
1223
8150
747
4235
2.04
50.45
4.5
3.6
0.00
0.00
estimate
0.04
436
1498
252
891
2.93
49.27
2.6
1.4
368.48
311.51
mu/l
1.60
223
793
1238
8437
1.93
48.09
12.0
7.5
—
—
—
0
0
757
4382
2.00
47.67
4.4
2.9
—
—
—
0
0
54
7
75.79
47.22
2.6
2.3
52.79
101.30
pmol/l
—
39
7
448
2142
2.26
46.50
3.6
2.5
2.47
2.45
g/l
0.29
414
1998
1290
8973
1.92
46.38
10.3
7.0
31.58
31.44
%
0.15
1250
8512
624
3404
2.06
46.11
4.1
2.6
6.21
6.73
e6/l
0.40
572
3027
477
2369
2.19
44.94
3.6
2.5
12.79
13.60
umol/l
1.54
441
2236
279
1097
2.64
44.39
7.3
5.2
72.61
64.43
ng/l
0.65
233
1014
468
2324
2.18
44.01
10.3
6.2
0.81
0.82
mmol/l
0.79
444
2197
287
1161
2.57
43.04
1.7
1.5
—
—
—
0
0
502
2584
2.12
42.92
2.1
1.6
40955244.07
25011901.50
pmol/l
0.22
398
2179
1259
8832
1.86
42.44
10.0
6.8
53.29
53.73
%
0.55
1219
8384
1391
10093
1.87
41.82
14.4
9.4
3.80
3.84
e9/l
0.25
1263
8648
1270
8960
1.85
41.74
10.1
7.0
0.60
0.56
e9/l
4.09
1134
7633
1270
8965
1.85
41.60
10.1
7.0
0.04
0.04
e9/l
0.91
1134
7636
151
438
3.47
40.94
1.4
1.4
301.82
309.49
ug/g
0.16
102
236
1298
9273
1.83
40.36
10.9
7.4
0.21
0.20
e9/l
0.76
1167
8047
1069
7267
1.80
38.52
10.6
6.4
12.96
14.27
umol/l
0.85
1011
6800
93
200
4.61
38.02
3.5
3.7
78.04
1493.33
u/ml
0.62
81
189
1288
9282
1.80
37.79
10.1
6.9
2.12
2.11
e9/l
0.08
1164
8134
1856
15094
2.16
36.74
6.1
4.3
1.81
1.97
mu/l
1.23
1734
14017
787
5016
1.78
34.14
5.0
3.4
66.58
69.44
e6/l
0.03
653
3795
735
4632
1.78
32.86
4.7
3.3
0.28
0.33
e6/l
0.45
616
3454
677
4167
1.80
32.76
2.9
2.5
3.13
2.77
mg/l
3.67
600
3603
1262
9266
1.72
32.39
8.2
5.5
6.36
6.38
mmol/l
0.15
1203
8560
68
130
5.14
31.91
1.8
1.2
—
—
nmol/l
—
0
0
726
4618
1.76
31.06
4.7
3.2
—
—
—
0
0
66
130
4.98
29.95
2.7
2.1
—
—
—
0
0
61
112
5.34
29.94
1.0
1.0
—
—
—
0
0
788
5177
1.71
29.74
1.5
1.6
1.07
2.47
u/ml
4.12
188
1153
856
5771
1.69
29.22
15.7
11.4
1.18
1.20
inr
0.48
490
1701
683
4340
1.74
28.91
3.5
2.6
58.88
76.92
u/l
0.47
620
4020
1489
11620
1.71
28.73
5.5
4.0
11.03
9.95
mm/h
2.27
1381
10788
575
3493
1.78
28.39
3.8
3.4
—
—
—
0
0
69
149
4.55
28.08
1.8
1.2
—
—
—
0
0
403
2218
1.91
27.23
4.5
2.8
2.45
2.43
mmol/l
1.05
363
1919
717
4706
1.68
26.46
1.8
1.5
1.96
1.98
g/l
0.06
371
2656
521
3137
1.77
26.22
4.2
3.8
925.33
1183.29
ng/l
1.34
437
2648
1574
12611
1.69
25.95
5.9
4.7
38.00
38.48
mmol/mol
1.20
1469
11743
290
1465
2.03
24.98
1.4
1.4
—
—
—
0
0
1863
15743
1.89
24.51
24.2
14.7
16.21
14.15
%
0.48
1838
15469
569
3590
1.70
23.92
6.3
4.0
—
—
—
0
0
861
6040
1.60
23.73
5.9
3.9
76.11
83.61
e6/l
0.12
668
4046
1426
15762
0.62
23.69
23.1
15.1
333.51
333.74
g/l
0.42
1417
15626
199
899
2.23
22.83
21.2
13.6
1.39
1.14
mg/l
4.73
188
867
96
302
3.14
22.81
8.4
3.6
—
—
—
0
0
704
4743
1.62
22.71
10.3
7.5
—
—
—
0
0
1085
8092
1.56
22.58
5.8
4.6
0.00
0.00
estimate
0.50
455
1552
1084
8092
1.56
22.40
4.5
3.3
0.00
0.00
estimate
0.75
460
1584
263
1332
2.01
22.39
4.4
3.5
66.97
68.07
e9/l
0.19
185
909
1089
8164
1.55
21.89
4.5
3.4
0.00
0.00
estimate
0.50
448
1502
335
1855
1.86
21.85
5.7
4.2
1.59
1.60
%
0.07
300
1702
664
4485
1.60
20.83
4.2
3.2
34.61
49.09
ng/l
0.60
448
2687
61
154
3.87
20.29
1.3
1.3
2057.43
355.48
pmol/l
0.53
54
136
90
296
2.99
19.84
1.7
1.4
0.31
0.40
nmol/l
0.70
69
238
1072
8194
1.49
18.44
4.1
2.9
99.43
85.98
ug/l
1.35
979
7654
27
36
7.26
18.08
2.3
1.1
470.76
69.03
nmol/24h
0.50
27
36
275
1523
1.83
17.74
4.8
3.0
9.34
9.93
g/l
1.73
251
1417
193
953
2.03
17.52
1.3
1.2
—
—
—
0
0
721
5123
1.52
17.39
3.3
2.4
—
—
—
0
0
33
60
5.33
16.42
8.4
9.0
2.28
2.48
mg/l
0.19
27
50
203
1045
1.95
16.36
3.6
4.2
9.65
22.70
ug/l
0.84
150
834
540
3666
1.54
15.83
1.8
1.7
1.47
1.32
mmol/l
3.18
377
3184
106
429
2.44
15.65
2.1
2.0
1.92
2.28
ug/l
0.15
87
377
29
49
5.73
15.58
2.3
1.8
—
—
—
0
0
45
113
3.87
15.13
1.3
1.1
—
—
—
0
0
52
145
3.49
15.04
2.7
3.2
—
—
—
0
0
92
360
2.51
14.61
3.0
2.3
130.24
132.02
g/l
0.27
85
291
77
279
2.70
14.27
4.4
2.9
1.52
1.43
e9/l
0.24
70
218
302
1831
1.67
14.04
1.6
1.2
—
—
—
0
0
334
2080
1.63
13.98
2.4
1.7
1566.61
1153.98
nmol/l
9.88
242
1564
414
2717
1.57
13.90
2.8
2.8
102.80
111.64
ug/g
0.33
311
2175
1327
10901
1.42
13.70
5.7
4.0
1165.13
1720.97
e6/l
0.22
24
131
28
52
5.21
13.63
1.1
1.2
—
—
—
0
0
216
1204
1.80
13.54
2.4
1.8
1.10
1.19
g/l
0.61
203
1127
640
4643
1.45
13.15
3.2
2.7
—
—
—
0
0
461
3140
1.51
12.98
3.6
3.0
1709.09
5276.66
umol/l
2.34
415
2802
35
82
4.14
12.94
2.4
2.5
—
—
—
0
0
1863
16427
1.57
12.58
23.5
13.2
3.94
3.94
mmol/l
0.00
1817
15894
59
199
2.89
12.53
2.4
1.6
283.84
289.28
mosm/kgh2o
1.12
49
151
21
32
6.33
12.47
1.2
1.3
—
—
—
0
0
1860
16402
1.57
12.47
23.1
13.2
139.43
139.52
mmol/l
1.09
1820
15915
46
138
3.24
11.93
1.5
1.6
—
—
—
0
0
313
2011
1.57
11.38
14.6
7.5
7.41
7.40
ph
0.13
65
115
1157
9449
1.37
11.34
4.5
3.2
—
—
—
0
0
1975
17747
1.66
11.28
18.8
10.4
—
—
—
0
0
1364
11440
1.37
11.26
5.7
4.0
—
—
—
0
0
26
55
4.57
10.94
2.3
3.3
—
—
—
0
0
68
266
2.49
10.88
4.2
2.4
72.36
72.22
mmol/l
0.01
56
229
687
5187
1.39
10.87
4.4
3.6
30.84
32.09
u/l
0.65
643
4948
26
57
4.41
10.48
2.5
3.4
7.41
7.42
ph
0.17
20
17
274
1749
1.57
10.20
1.2
1.2
—
—
—
0
0
567
4181
1.40
10.20
8.1
5.4
89.20
89.45
%
0.08
555
4095
307
2018
1.53
10.02
1.3
1.2
—
—
—
0
0
1922
17292
1.52
9.33
14.8
9.2
26.28
25.76
u/l
0.50
1861
16694
28
73
3.71
9.02
2.8
2.5
530.30
509.83
min
0.45
23
53
305
2059
1.49
8.72
2.3
1.9
—
—
—
0
0
51
195
2.54
8.62
3.0
4.1
—
—
—
0
0
24
58
3.99
8.58
1.3
1.9
20.25
19.47
nmol/l
—
8
19
32
95
3.26
8.51
3.5
1.8
—
—
—
0
0
265
1760
1.50
8.19
13.7
7.4
23.36
23.68
mmol/l
1.36
265
1749
513
3839
1.36
8.19
2.5
2.3
145.23
255.72
u/l
3.97
470
3647
325
2264
1.44
7.86
1.7
1.4
485.07
522.27
titre
0.13
71
423
1231
10448
1.29
7.82
5.1
3.2
49.94
38.69
u/l
2.78
1147
9885
52
212
2.38
7.70
1.3
1.3
7.13
6.39
g/l
0.75
32
169
52
212
2.38
7.70
1.3
1.3
0.37
0.37
g/l
0.01
32
167
52
212
2.38
7.70
1.3
1.3
2.41
2.39
g/l
0.02
32
168
156
932
1.65
7.63
2.7
3.1
65.92
66.28
g/l
0.22
145
861
52
213
2.37
7.63
1.4
1.3
—
—
—
0
0
294
2022
1.45
7.61
2.1
1.6
—
—
—
0
0
408
2977
1.38
7.56
1.6
1.5
21.78
20.37
nmol/l
0.95
344
2550
231
1524
1.50
7.36
1.6
1.3
322.99
257.17
u/ml
0.50
211
1424
50
207
2.34
7.18
5.1
3.2
300.27
396.59
e6/l
0.66
37
129
29
91
3.08
7.09
2.7
2.5
717.17
617.49
ml
0.47
23
63
271
1861
1.45
7.06
6.7
4.3
5.95
7.01
umol/l
0.70
209
1570
25
72
3.35
7.01
3.9
3.8
—
—
—
0
0
142
852
1.64
6.85
5.3
5.0
22.93
22.43
s
0.39
129
788
60
274
2.13
6.84
3.5
3.8
52.06
72.49
mg/l
0.40
25
230
60
274
2.13
6.84
3.5
3.8
34.10
41.71
mg/l
0.28
25
230
445
3354
1.34
6.63
3.0
2.6
2.10
1.22
mg/l
0.96
324
2454
575
4498
1.30
6.57
4.0
3.6
6.87
7.92
mmol/l
5.90
480
3943
288
2027
1.41
6.55
15.2
9.6
—
—
—
0
0
20
52
3.71
6.51
1.6
1.6
—
—
—
0
0
157
980
1.58
6.45
5.1
3.8
217.34
181.15
ng/l
0.30
146
883
78
401
1.89
6.43
1.7
1.3
9.00
4.02
ug/l
1.04
71
381
19
49
3.74
6.26
2.8
3.3
8.72
26.50
mg/l
—
5
21
55
252
2.12
6.24
5.0
3.0
670.73
567.11
e6/l
0.60
45
189
813
6680
1.26
6.21
3.7
3.1
6.10
6.04
ph
0.23
70
625
54
249
2.10
6.04
5.0
3.0
0.17
0.20
e9/l
0.48
45
189
98
552
1.73
6.02
2.7
1.8
—
—
—
0
0
38
151
2.43
6.02
5.4
7.6
1362.69
78.87
g/mol
0.47
33
140
95
531
1.75
5.99
2.8
1.8
77.21
97.59
u/ml
0.68
13
67
19
51
3.59
5.93
2.0
1.4
2.71
5.58
%
—
7
12
309
2238
1.37
5.92
14.6
7.0
0.94
1.46
mmol/l
1.68
234
1809
2095
19474
1.68
5.89
29.0
17.3
264.50
259.73
e9/l
2.28
2049
18828
16
38
4.05
5.89
1.1
1.3
—
—
—
0
0
2094
19470
1.67
5.77
29.6
17.6
39.52
40.19
%
1.88
2022
18458
254
1791
1.40
5.71
2.0
1.5
—
—
—
0
0
2095
19489
1.66
5.66
28.9
17.2
88.84
89.02
fl
0.80
2075
19212
2095
19490
1.66
5.65
28.9
17.1
29.60
29.77
pg
3.84
2075
19212
30
110
2.63
5.61
2.5
6.2
73.32
90.64
mg/l
0.64
25
100
28
99
2.73
5.61
2.1
1.5
28.74
38.72
%
0.72
19
67
2095
19493
1.66
5.60
29.0
17.2
6.87
6.83
e9/l
0.34
2048
18794
2095
19493
1.66
5.60
29.0
17.2
4.49
4.54
e12/l
4.78
2047
18791
35
139
2.43
5.57
2.0
1.6
69.79
54.46
%
1.47
24
98
2095
19502
1.65
5.47
29.4
17.4
132.14
134.57
g/l
11.79
2073
19228
1881
17169
1.35
5.45
20.5
11.7
21.05
22.60
mg/l
1.23
1526
12897
682
5565
1.25
5.36
2.1
1.9
—
—
—
0
0
39
166
2.27
5.34
1.7
1.4
2.60
7.10
u/ml
1.52
21
107
19
55
3.33
5.33
1.1
1.3
148.74
152.19
mmol/24h
0.07
19
55
82
456
1.75
5.30
4.1
3.3
36.72
33.53
umol/l
0.73
76
418
81
450
1.75
5.26
1.8
1.5
85.45
70.95
titre
0.38
11
42
121
1738
0.65
5.14
1.1
1.3
—
—
—
0
0
32
127
2.43
5.12
1.3
1.1
—
—
—
0
0
109
663
1.60
5.05
2.7
1.6
256.30
190.21
u/ml
1.40
68
336
336
2529
1.32
4.97
1.3
1.2
32.72
27.43
iu/ml
0.22
93
736
42
191
2.13
4.93
1.7
1.5
—
—
—
0
0
198
1381
1.41
4.75
1.3
1.2
119.35
159.49
iu/ml
0.65
62
499
24
87
2.66
4.63
4.0
3.0
972.71
965.76
u/ml
0.01
24
87
329
2494
1.31
4.62
4.6
3.9
30.54
30.27
s
0.48
316
2438
41
190
2.09
4.60
2.2
2.1
—
—
—
0
0
16
46
3.35
4.55
1.4
1.2
—
—
—
0
0
38
172
2.14
4.53
7.3
4.0
—
—
—
0
0
44
212
2.01
4.47
1.2
1.4
—
—
—
0
0
66
1056
0.59
4.46
1.3
1.3
—
—
—
0
0
105
655
1.56
4.41
2.1
2.5
—
—
—
0
0
113
718
1.53
4.37
6.6
5.5
0.35
0.29
g/l
0.19
91
440
60
324
1.79
4.34
1.4
1.7
0.75
0.82
g/l
0.17
39
266
231
1682
1.35
4.28
16.2
7.7
—
—
—
0
0
46
229
1.94
4.27
1.7
1.6
—
—
—
0
0
98
607
1.57
4.25
2.3
1.7
0.21
0.22
g/l
0.37
93
579
49
250
1.90
4.24
1.3
1.3
—
—
—
0
0
25
97
2.48
4.24
1.2
1.2
1.07
1.06
ratio
0.21
15
44
45
224
1.94
4.19
4.0
3.4
0.83
1.08
%
0.38
45
204
416
3292
1.26
4.15
3.4
3.4
118.82
244.40
mg/l
0.96
261
2196
311
2376
1.30
4.12
1.3
1.2
6.03
10.85
u/ml
1.15
118
868
19
65
2.81
4.10
1.1
1.4
132.26
141.79
nmol/l
0.39
19
65
99
621
1.55
4.08
2.4
1.7
1.15
1.16
g/l
0.19
93
590
171
1197
1.40
4.05
1.2
1.1
—
39.75
—
0
10
11
21
5.04
3.98
7.0
5.9
39.27
19.89
ug/min
0.72
11
15
51
271
1.82
3.92
2.6
2.6
—
—
—
0
0
87
543
1.56
3.70
2.4
2.0
1.23
1.42
g/l
1.03
71
483
10
19
5.06
3.68
1.3
1.4
—
—
—
0
0
8
12
6.40
3.55
1.6
1.8
104.13
91.83
ng/l
—
8
12
18
65
2.67
3.54
2.8
2.9
—
—
—
0
0
19
71
2.58
3.51
2.9
1.9
—
—
—
0
0
167
1195
1.37
3.50
2.3
1.5
—
—
—
0
0
69
416
1.61
3.41
2.0
3.6
33.41
3452.49
u/ml
0.79
56
351
73
449
1.58
3.33
1.6
1.4
—
1276.25
titre
—
0
8
22
91
2.33
3.31
1.5
1.2
—
—
—
0
0
31
150
1.99
3.19
3.2
1.6
—
—
—
0
0
71
442
1.56
3.10
2.5
3.0
—
—
—
0
0
21
415
0.48
2.95
8.5
9.0
—
—
—
0
0
5
5
9.59
2.90
2.0
1.2
546.00
1087.60
nmol/l
—
5
5
200
1515
1.29
2.86
1.6
1.4
—
—
—
0
0
19
79
2.31
2.85
1.3
1.4
—
—
—
0
0
316
3588
0.82
2.80
4.2
3.5
1.02
1.02
kg/l
0.43
66
578
18
74
2.34
2.77
3.9
7.4
—
—
—
0
0
22
99
2.14
2.76
4.1
3.9
1.87
3.31
%
—
8
38
25
119
2.02
2.73
1.2
1.2
—
—
—
0
0
77
1056
0.69
2.69
3.7
3.4
—
—
—
0
0
20
89
2.16
2.59
1.4
2.5
228.43
145.88
umol/l
—
7
51
416
3454
1.19
2.54
4.6
4.0
57.26
8.83
mg/mmol
0.59
260
2252
12
42
2.75
2.54
3.3
1.8
—
—
—
0
0
14
54
2.49
2.48
1.2
1.1
—
—
—
0
0
16
66
2.33
2.47
2.6
3.9
92.51
153.83
ug/l
0.79
16
66
9
25
3.46
2.46
1.4
1.8
—
—
—
0
0
80
539
1.44
2.45
1.2
1.2
—
—
—
0
0
187
1436
1.27
2.43
2.7
2.4
32.63
37.64
u/l
0.45
172
1203
68
445
1.48
2.42
3.6
2.1
1.11
0.62
nmol/l
1.80
63
373
35
195
1.73
2.41
1.6
1.6
—
—
—
0
0
21
99
2.04
2.38
1.3
1.4
—
—
—
0
0
37
211
1.69
2.36
1.4
1.3
—
45.74
—
0
10
16
68
2.26
2.32
1.3
1.8
1.47
1.07
nmol/l
—
9
51
30
163
1.77
2.26
1.2
1.1
—
—
—
0
0
7
17
3.95
2.26
1.0
1.2
—
—
—
0
0
8
22
3.49
2.26
9.1
8.4
—
—
—
0
0
75
509
1.43
2.24
4.2
3.6
9.69
8.24
umol/l
0.37
65
410
20
95
2.03
2.23
1.7
1.4
82.65
75.00
umol/l
0.58
20
95
335
2764
1.19
2.20
4.6
3.1
3.89
2.68
e6/l
0.76
200
1503
40
238
1.62
2.19
1.3
1.4
—
—
—
0
0
24
124
1.86
2.13
1.8
2.6
0.70
1.80
g/24h
2.07
15
70
604
5234
1.14
2.11
1.9
1.8
95.25
95.96
pmol/l
0.13
336
2743
18
329
0.52
2.09
2.3
3.8
4.00
3.88
mmol/l
0.51
18
324
39
235
1.60
2.05
4.4
4.0
—
—
—
0
0
57
375
1.47
2.03
1.2
1.2
—
—
—
0
0
11
42
2.52
2.00
1.3
1.2
—
—
—
0
0
12
48
2.40
2.00
2.1
1.9
—
—
—
0
0
32
187
1.65
1.91
1.6
1.2
—
—
—
0
0
68
469
1.40
1.90
2.5
2.8
3.61
3.52
mmol/l
0.36
62
445
7
21
3.20
1.87
6.6
3.0
4.51
4.56
mmol/l
—
7
21
5
11
4.36
1.87
5.6
4.8
5.26
7.13
mmol/l
—
5
11
12
50
2.31
1.84
1.2
1.4
—
—
—
0
0
56
375
1.44
1.84
1.3
1.1
11.52
183.22
iu/ml
5.02
21
117
172
1356
1.23
1.84
2.6
2.3
9397.27
7461.23
u/l
0.18
56
527
8
27
2.84
1.84
1.8
1.4
—
—
—
0
0
8
27
2.84
1.84
1.6
2.0
—
—
—
0
0
140
1081
1.26
1.80
2.4
2.4
5.16
5.56
e9/l
0.12
121
928
848
7568
1.12
1.80
3.4
2.7
—
—
—
0
0
5
12
4.00
1.75
1.0
1.4
—
—
—
0
0
67
469
1.38
1.74
2.7
2.9
10.55
12.35
e6/l
0.12
47
343
302
2523
1.17
1.74
1.8
1.6
—
—
—
0
0
67
470
1.38
1.72
2.7
2.9
328.63
8735.05
e6/l
0.50
51
355
38
239
1.53
1.71
1.1
1.1
1.46
1.46
g/l
0.03
38
221
29
171
1.63
1.70
2.6
4.0
73.81
83.37
u/ml
0.08
12
49
373
4003
0.87
1.68
3.9
3.3
—
—
—
0
0
6
18
3.20
1.67
1.3
1.0
—
—
—
0
0
66
465
1.37
1.66
2.5
2.6
224.94
444.96
ug/l
1.14
59
434
27
158
1.64
1.64
1.4
1.2
—
—
—
0
0
31
188
1.59
1.64
1.0
1.1
—
—
—
0
0
62
434
1.38
1.63
2.0
1.9
2.33
4.58
iu/l
4.44
23
151
39
250
1.50
1.62
2.5
3.0
—
—
—
0
0
223
1828
1.19
1.62
1.7
1.9
—
—
—
0
0
24
137
1.68
1.60
1.5
1.2
—
—
—
0
0
6
20
2.88
1.50
4.3
4.4
3.08
3.87
mg/l
—
6
20
9
35
2.47
1.49
1.0
1.3
—
—
—
0
0
6
21
2.74
1.43
1.3
1.1
—
—
—
0
0
15
77
1.87
1.42
1.1
1.3
—
—
—
0
0
9
38
2.27
1.40
1.4
1.2
—
—
—
0
0
45
308
1.41
1.38
1.5
1.2
—
—
—
0
0
13
64
1.95
1.38
1.1
1.1
—
—
—
0
0
12
58
1.99
1.34
1.5
1.2
—
—
—
0
0
44
302
1.40
1.34
1.0
1.1
—
—
—
0
0
17
93
1.76
1.33
1.2
1.6
—
—
—
0
0
457
4007
1.12
1.30
1.8
1.7
—
—
—
0
0
1505
13973
1.10
1.29
4.6
3.7
5.74
5.72
mmol/l
0.34
1362
12779
575
5110
1.10
1.27
3.6
2.5
—
—
—
0
0
17
95
1.72
1.25
1.0
1.1
1155.82
1497.53
miu/ml
0.62
17
95
61
754
0.77
1.24
1.7
1.5
—
—
—
0
0
129
1464
0.83
1.22
2.0
2.0
—
—
—
0
0
129
1462
0.84
1.20
2.0
2.0
—
—
—
0
0
41
285
1.38
1.19
1.3
1.3
2.27
4.21
u/ml
2.31
22
133
128
1449
0.84
1.18
2.0
2.0
—
—
—
0
0
127
1438
0.84
1.18
2.0
2.0
—
—
—
0
0
26
166
1.51
1.16
1.1
1.1
—
—
—
0
0
5
19
2.52
1.15
1.0
1.3
—
—
—
0
0
0
34
0.00
1.15
0.0
1.0
—
—
—
0
0
80
616
1.25
1.14
1.1
1.1
0.87
9.07
u/ml
—
6
93
61
740
0.78
1.10
1.6
1.5
—
—
—
0
0
5
20
2.40
1.09
3.4
1.6
—
—
—
0
0
47
340
1.33
1.08
1.4
1.6
—
5.20
—
0
5
88
691
1.23
1.07
1.3
1.2
—
—
—
0
0
82
639
1.24
1.07
2.5
2.4
—
—
—
0
0
61
737
0.79
1.07
1.6
1.5
—
—
—
0
0
40
283
1.36
1.06
3.7
2.4
74.51
98.82
ug/min
0.23
28
182
21
131
1.54
1.05
1.2
1.2
—
—
—
0
0
142
1170
1.17
1.04
4.7
3.8
—
—
—
0
0
39
276
1.36
1.04
1.1
1.2
—
—
—
0
0
559
5706
0.92
1.02
1.9
1.7
—
—
—
0
0
326
2847
1.11
1.02
4.5
2.9
0.87
1.06
e6/l
0.45
193
1580
7
34
1.97
0.98
2.9
1.7
—
—
—
0
0
7
34
1.97
0.98
2.1
2.1
—
—
—
0
0
7
34
1.97
0.98
2.3
2.4
—
—
—
0
0
161
1348
1.15
0.98
8.8
9.6
0.69
0.82
mmol/l
0.15
130
1066
51
380
1.29
0.98
2.9
2.6
—
—
—
0
0
87
691
1.21
0.97
3.0
5.4
—
—
—
0
0
34
239
1.37
0.96
1.8
1.4
—
—
—
0
0
22
143
1.48
0.94
1.0
1.0
—
—
—
0
0
24
159
1.45
0.94
3.3
4.9
—
—
—
0
0
63
486
1.25
0.93
6.7
5.2
—
—
—
0
0
10
164
0.58
0.92
1.8
1.6
—
—
—
0
0
46
342
1.29
0.91
1.9
2.2
8.24
11.22
mg/l
1.16
39
319
6
27
2.13
0.91
1.2
1.1
—
—
—
0
0
6
27
2.13
0.91
1.2
1.1
—
—
—
0
0
6
27
2.13
0.91
1.2
1.1
—
—
—
0
0
160
1351
1.14
0.88
8.8
9.6
13.21
13.32
kpa
0.08
154
1300
120
992
1.17
0.88
1.1
1.2
—
—
—
0
0
39
285
1.32
0.88
1.1
1.1
3.39
7.47
iu/ml
—
8
51
160
1352
1.14
0.88
8.8
9.6
5.26
5.16
kpa
0.65
154
1299
123
1351
0.86
0.84
2.0
2.1
—
—
—
0
0
49
374
1.26
0.81
1.1
1.1
0.72
3.95
u/ml
2.47
13
153
0
23
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
13
191
0.65
0.79
1.1
1.4
—
183.33
—
0
9
104
1148
0.86
0.78
2.1
2.2
—
—
—
0
0
92
1023
0.85
0.76
3.2
2.5
—
—
—
0
0
13
189
0.66
0.75
1.4
1.6
—
—
—
0
0
9
54
1.60
0.72
7.4
6.8
—
—
—
0
0
84
934
0.86
0.70
2.0
2.3
5.34
7.12
ug/l
0.93
72
823
12
73
1.58
0.70
2.0
1.2
—
—
—
0
0
12
73
1.58
0.70
2.0
1.2
—
—
—
0
0
12
73
1.58
0.70
2.0
1.2
—
—
—
0
0
24
170
1.36
0.69
1.1
1.2
41.09
34.11
mg/l
0.34
14
134
5
26
1.84
0.68
1.8
1.3
—
—
—
0
0
241
2501
0.91
0.67
3.2
3.7
371.30
594.87
ng/l
0.92
154
1730
16
106
1.45
0.66
1.1
1.2
—
—
—
0
0
1478
14422
0.94
0.65
4.5
4.0
2.66
2.75
mmol/l
3.63
1336
13407
5
28
1.71
0.63
2.8
1.2
—
—
—
0
0
1392
13596
0.95
0.61
3.9
3.4
1.30
1.22
mmol/l
3.74
1252
12635
82
900
0.87
0.61
1.5
1.6
—
—
—
0
0
141
1217
1.12
0.61
9.5
10.1
94.28
95.66
%
0.95
136
1173
0
22
0.00
0.58
0.0
1.0
—
—
—
0
0
27
202
1.28
0.57
3.3
4.3
—
—
—
0
0
1454
14167
0.95
0.56
4.3
3.6
1.43
1.46
mmol/l
2.16
1314
13207
17
120
1.36
0.52
1.1
1.2
—
—
—
0
0
399
4017
0.94
0.52
3.7
2.4
—
—
—
0
0
6
95
0.60
0.52
3.3
2.3
—
—
—
0
0
22
163
1.30
0.51
1.1
1.1
177.62
217.80
mg/l
0.75
16
141
11
72
1.47
0.50
7.2
4.4
—
—
—
0
0
324
3277
0.94
0.49
1.9
1.6
—
—
—
0
0
21
257
0.78
0.49
1.1
1.2
—
—
—
0
0
96
824
1.12
0.48
1.1
1.2
4.68
6.34
u/ml
0.62
65
573
10
137
0.70
0.47
1.4
2.7
107.20
105.49
mmol/l
—
10
137
49
546
0.86
0.47
1.4
1.2
—
—
—
0
0
7
46
1.46
0.46
3.3
2.3
—
—
—
0
0
1471
14297
0.95
0.46
4.4
3.7
4.49
4.60
mmol/l
4.29
1332
13407
112
1177
0.91
0.45
1.5
1.4
—
—
—
0
0
15
107
1.34
0.45
1.0
1.1
—
—
—
0
0
21
158
1.28
0.44
1.3
1.2
—
—
—
0
0
13
91
1.37
0.43
1.5
1.4
1.03
0.99
g/l
0.09
13
91
546
5043
1.05
0.43
2.1
2.1
—
—
—
0
0
60
505
1.14
0.42
1.1
1.1
8.21
8.96
u/ml
0.10
36
273
6
90
0.64
0.42
1.2
1.2
—
—
—
0
0
6
91
0.63
0.42
1.0
1.1
—
—
—
0
0
20
240
0.80
0.42
1.7
1.7
—
—
—
0
0
25
292
0.82
0.41
1.8
1.7
9396.00
13745.22
e6/l
0.66
15
214
0
15
0.00
0.41
0.0
1.0
—
26.49
—
0
9
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
5
32
1.50
0.41
46.8
10.6
—
—
—
0
0
5
32
1.50
0.41
1.6
1.1
—
—
—
0
0
20
152
1.26
0.40
1.2
1.3
—
—
—
0
0
305
2781
1.06
0.40
4.6
4.6
1.67
2.67
ug/l
2.04
263
2482
336
3366
0.95
0.39
1.8
1.8
—
—
—
0
0
25
196
1.22
0.39
30.4
16.5
10.80
11.38
%
0.35
25
196
78
827
0.90
0.39
1.3
1.3
225.52
241.50
miu/ml
0.15
36
409
10
131
0.73
0.38
1.4
2.7
—
—
—
0
0
5
35
1.37
0.37
1.8
1.6
—
—
—
0
0
13
94
1.33
0.37
1.3
1.4
—
—
—
0
0
10
69
1.39
0.36
1.0
1.4
—
—
—
0
0
9
68
1.27
0.36
1.0
1.0
—
—
—
0
0
158
1615
0.93
0.36
3.3
2.8
0.72
0.75
ug/l
0.26
109
1007
19
146
1.25
0.36
2.0
1.7
—
—
—
0
0
41
341
1.15
0.36
1.1
1.1
—
—
—
0
0
29
234
1.19
0.35
1.1
1.3
1.71
17.93
u/ml
0.94
19
185
77
812
0.90
0.35
14.2
11.6
0.98
1.29
%
2.98
77
806
45
378
1.14
0.35
1.4
1.3
—
—
—
0
0
11
138
0.76
0.33
1.4
2.7
4.34
3.99
mmol/l
0.93
11
138
6
44
1.31
0.33
1.3
1.1
—
—
—
0
0
23
263
0.84
0.33
1.2
1.6
—
1810.00
—
0
8
13
96
1.30
0.33
1.2
1.3
177.52
188.91
pmol/l
0.12
13
96
91
801
1.09
0.33
1.1
1.2
2.07
1.08
u/ml
0.30
54
511
55
472
1.12
0.32
1.1
1.1
1.21
0.33
u/ml
0.35
22
211
10
71
1.35
0.32
2.0
2.5
14.40
17.52
umol/l
—
10
71
40
435
0.88
0.32
2.4
2.2
—
—
—
0
0
23
185
1.19
0.30
3.2
3.2
0.97
0.82
nmol/l
0.55
15
149
67
584
1.10
0.30
1.5
1.6
—
—
—
0
0
78
686
1.09
0.29
12.8
13.3
—
—
—
0
0
13
98
1.27
0.29
1.0
1.1
—
—
—
0
0
13
98
1.27
0.29
1.0
1.0
—
—
—
0
0
51
542
0.90
0.29
1.1
1.1
—
—
—
0
0
8
102
0.75
0.29
1.1
1.2
—
1.87
nmol/l
—
0
16
57
496
1.10
0.27
2.7
3.4
—
—
—
0
0
9
115
0.75
0.27
2.1
2.6
—
—
—
0
0
78
690
1.09
0.27
1.5
1.7
—
—
—
0
0
99
885
1.07
0.26
1.2
1.2
1.91
3.17
u/ml
0.69
64
585
84
747
1.08
0.26
1.5
1.3
—
—
—
0
0
5
71
0.67
0.26
3.4
2.6
—
—
—
0
0
5
71
0.67
0.26
6.8
5.2
—
—
—
0
0
167
1522
1.05
0.25
1.5
1.4
—
—
—
0
0
14
109
1.23
0.25
6.9
5.5
—
42.55
—
0
15
19
154
1.18
0.24
1.7
2.3
1.59
1.97
mmol/l
—
10
123
24
199
1.16
0.24
1.1
1.4
—
—
—
0
0
13
101
1.23
0.24
1.3
1.4
541.40
46220.32
e6/l
—
5
60
43
453
0.91
0.22
1.3
1.2
—
—
—
0
0
88
790
1.07
0.22
1.1
1.2
3.45
3.01
u/ml
0.12
62
542
79
809
0.93
0.22
13.8
11.7
0.65
0.69
%
0.48
79
804
22
183
1.15
0.21
2.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
67
689
0.93
0.21
3.2
2.8
—
—
—
0
0
5
41
1.17
0.21
1.6
2.1
—
—
—
0
0
0
13
0.00
0.20
0.0
1.1
—
7.02
—
0
8
9
106
0.81
0.20
1.1
1.1
—
—
—
0
0
40
349
1.10
0.20
1.0
1.0
10.70
8.43
mu/l
0.57
33
302
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
52
460
1.08
0.20
1.4
1.2
—
—
—
0
0
6
48
1.20
0.19
2.3
1.6
—
—
—
0
0
107
973
1.06
0.19
2.6
2.7
—
—
—
0
0
12
95
1.21
0.19
1.1
1.1
135.83
229.46
iu/ml
1.28
12
95
13
104
1.20
0.19
1.1
1.2
—
54.20
—
0
11
6
50
1.15
0.19
1.0
1.2
—
—
—
0
0
52
463
1.08
0.17
1.4
1.2
—
—
—
0
0
37
325
1.09
0.17
1.3
1.4
8.86
3.12
u/ml
1.03
24
208
5
65
0.74
0.17
1.2
1.3
—
—
—
0
0
8
67
1.14
0.16
3.0
2.4
—
180.09
—
0
12
42
373
1.08
0.15
4.3
7.1
1.25
1.26
mmol/l
0.04
34
325
60
541
1.06
0.15
1.1
1.1
5.21
6.99
u/ml
0.32
37
319
9
78
1.11
0.15
3.9
2.7
—
—
—
0
0
25
263
0.91
0.14
1.2
1.2
1.23
2.39
u/ml
0.45
14
153
31
273
1.09
0.14
1.0
1.0
3.16
3.28
kpa
0.22
25
227
31
275
1.08
0.12
1.0
1.0
-0.63
-1.47
mmol/l
—
6
55
31
275
1.08
0.12
1.0
1.0
—
—
—
0
0
31
275
1.08
0.12
1.0
1.0
7.54
7.14
kpa
0.61
25
229
28
290
0.92
0.12
3.9
3.7
—
—
—
0
0
47
426
1.06
0.11
1.1
1.2
—
—
—
0
0
66
660
0.96
0.11
2.6
2.8
—
—
—
0
0
32
288
1.06
0.09
1.1
1.1
—
—
—
0
0
5
58
0.83
0.08
2.2
1.4
—
—
—
0
0
32
324
0.94
0.08
4.4
3.1
33.44
24.38
mg/l
0.72
24
202
22
196
1.08
0.08
1.4
1.4
—
—
—
0
0
42
385
1.05
0.07
22.8
9.8
—
—
—
0
0
13
113
1.10
0.07
1.3
1.4
901.67
2331.43
e6/l
—
6
79
32
321
0.95
0.06
1.2
1.4
3.07
13.97
u/ml
1.23
16
185
114
1072
1.02
0.05
1.3
1.3
53.34
43.23
au/ml
—
5
51
10
87
1.10
0.04
1.0
1.0
14.00
19.42
u/ml
—
5
56
80
780
0.98
0.04
1.1
1.1
—
—
—
0
0
124
1173
1.01
0.03
2.4
2.3
11.83
20.26
au/ml
—
6
90
104
1008
0.99
0.02
1.6
1.4
—
—
—
0
0
12
109
1.05
0.01
1.0
1.1
—
—
—
0
0
30
293
0.98
0.00
1.0
1.1
—
—
—
0
0
18
167
1.03
0.00
1.2
1.3
37.48
8.12
u/ml
0.47
18
156
11
105
1.00
0.00
1.1
1.1
—
—
—
0
0
12
111
1.04
0.00
2.8
2.6
44425.00
40274.18
ug/l
0.60
12
111
16
153
1.00
0.00
1.4
2.0
—
—
—
0
0
11
104
1.01
0.00
1.0
1.0
—
—
—
0
0
31
293
1.01
0.00
4.3
3.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.04
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.93
-0.00
1.0
1.1
3.80
3.93
u/ml
—
7
59
8
85
0.90
-0.00
5.5
3.3
—
—
—
0
0
5
57
0.84
-0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
94
0.92
-0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
8
81
0.95
-0.00
1.4
1.3
1.65
1.52
g/l
—
8
81
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.93
-0.00
1.7
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint E4_ENDODIS and mortality.

Females

Parameter HR [95% CI] p-value
E4_ENDODIS 2.214 [1.89, 2.6] < 0.001
Birth year 0.992 [0.98, 1.0] 0.06

During the follow-up period (1.1.1998 — 31.12.2019), 836 out of 14401 females with E4_ENDODIS died.

Males

Parameter HR [95% CI] p-value
E4_ENDODIS 2.624 [2.25, 3.06] < 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 808 out of 12884 males with E4_ENDODIS died.

Mortality risk

Mortality risk for people of age

years, who have E4_ENDODIS.

N-year risk Females Males
1 0.208% 0.389%
5 1.229% 2.819%
10 2.919% 6.793%
15 5.687% 13.4%
20 9.654% 22.642%

Relationships between endpoints

↥

Index endpoint: E4_ENDODIS – Other endocrine disorders

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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