Hepatic failure, not elsewhere classified

K11_HEPFAIL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K72
  • Hospital discharge: ICD-9 570
  • Hospital discharge: ICD-8 570
  • Hospital discharge: excluded ICD-8 57001
  • Cause of death: ICD-10 K72
  • Cause of death: ICD-9 570
  • Cause of death: ICD-8 570
  • Cause of death: excluded ICD-8 57001

2 out of 7 registries used, show all original rules.

1439

4. Check minimum number of events

None

1439

5. Include endpoints

None

1439

6. Filter based on genotype QC (FinnGen only)

1408

Control definitions (FinnGen only)

Control exclude
K11_LIVER

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K70-K77
Name in latin
Insufficientia hepatis non alibi classificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13134 5721 7234
Only index persons 9949 4454 5495
Unadjusted period prevalence (%)
Whole population 0.19 0.16 0.20
Only index persons 0.19 0.16 0.21
Median age at first event (years)
Whole population 60.26 60.66 59.96
Only index persons 60.52 60.24 60.75

-FinnGen-

Key figures

All Female Male
Number of individuals 1408 643 765
Unadjusted period prevalence (%) 0.29 0.23 0.35
Median age at first event (years) 60.62 57.78 63.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1439
Matched controls
14390
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.0
307.9
557
1051
C03DA01
ATC
spironolactone; oral
8.6
307.7
559
992
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
+∞
307.7
594
*
K72.9
ICD-10 Finland
Hepatic failure, unspecified
11241.6
307.7
650
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
40.2
307.7
225
66
R18
ICD-10 Finland
Ascites
43.6
307.7
256
71
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
10.5
307.7
473
640
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
+∞
304.3
281
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
31.4
273.6
182
66
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
+∞
272.8
253
*
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
216.2
202
*
A06AD11
ATC
lactulose; oral
5.3
187.4
503
1314
N17.9
ICD-10 Finland
Acute renal failure, unspecified
9.7
183.9
233
281
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
340.1
179.4
178
6
127
Kela drug reimbursment
Transplant complication
22.1
176.6
133
66
A05AA02
ATC
ursodeoxycholic acid; oral
34.9
172.7
110
34
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
21.0
171.3
132
69
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.4
169.1
745
2825
C03CA01
ATC
furosemide; systemic
4.3
163.1
779
3112
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
67.7
162.3
89
14
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.3
141.4
498
1571
L04AA06
ATC
mycophenolic acid; systemic
16.5
135.5
117
77
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
6.3
135.1
254
471
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
29.1
126.3
85
31
Z94.4
ICD-10 Finland
Liver transplant status
444.7
124.8
123
*
L04AD02
ATC
tacrolimus; systemic
26.1
122.9
86
35
TK800
NOMESCO Finland
Hemodialysis
11.4
117.8
127
121
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
37.5
109.3
68
19
JJC00
NOMESCO Finland
Allogenic transplantation of liver
1130.5
108.9
105
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.6
105.9
224
460
A07AA11
ATC
rifaximin; oral
277.2
102.2
103
*
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
20.1
100.3
78
41
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
+∞
100.2
95
*
K70.4
ICD-10 Finland
Alcoholic hepatic failure
992.1
96.1
93
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.5
94.9
445
1648
K70.1
ICD-10 Finland
Alcoholic hepatitis
+∞
93.8
89
*
L04AD01
ATC
ciclosporin; systemic
11.7
92.7
97
88
D64.9
ICD-10 Finland
Anaemia, unspecified
4.1
91.7
304
891
K83.0
ICD-10 Finland
Cholangitis
14.2
88.4
82
61
D97
ICPC
Liver disease NOS
32.3
81.6
53
17
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
27.2
80.1
55
21
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
+∞
79.9
76
*
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
409.1
78.6
78
*
A41.9
ICD-10 Finland
Sepsis, unspecified
6.3
76.6
137
238
K76.9
ICD-10 Finland
Liver disease, unspecified
97.8
75.8
83
9
JN3AD
NOMESCO Finland
Abdominal CT examination
3.7
75.5
284
900
WX872
NOMESCO Finland
Intensive care
5.0
75.0
177
396
K92.0
ICD-10 Finland
Haematemesis
8.2
74.7
102
132
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
263.5
74.1
75
*
P15
ICPC
Chronic alcohol abuse
7.1
72.5
113
170
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
67.4
848
5113
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
10.0
67.1
78
82
57009
ICD-8 Finland
Acute and subacute necrosis of liver, Unspecified
+∞
65.1
62
*
K76.7
ICD-10 Finland
Hepatorenal syndrome
+∞
65.1
62
*
A10AB05
ATC
insulin aspart; parenteral
4.0
64.1
199
549
UJK02
NOMESCO Finland
ERCP
7.1
61.7
96
144
JN4AD
NOMESCO Finland
Body CT examination
3.4
61.0
251
836
C07AA05
ATC
propranolol; systemic
2.8
60.8
385
1644
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.0
60.4
112
201
N17.8
ICD-10 Finland
Other acute renal failure
11.1
59.6
64
60
L04AX01
ATC
azathioprine; systemic
5.5
58.9
120
235
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
8.0
58.2
81
107
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
8.4
58.0
77
96
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.7
57.9
112
209
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
+∞
57.7
55
*
AA1AD
NOMESCO Finland
CT of head and brain
2.5
57.3
534
2745
WW500
NOMESCO Finland
Blood transfusion
5.0
57.3
129
276
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
56.2
441
2087
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
8.9
54.5
69
81
F10.20
ICD-10 Finland
Alcohol dependence currently independent
8.2
54.4
74
95
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.0
53.4
164
447
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
53.3
224
753
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.9
52.2
97
174
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.7
52.2
186
562
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
52.1
255
938
I50.9
ICD-10 Finland
Heart failure, unspecified
2.8
51.6
310
1276
K70.0
ICD-10 Finland
Alcoholic fatty liver
95.3
50.2
55
6
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
6.1
50.0
89
153
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
8.5
49.4
65
80
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.9
49.0
112
242
K92.1
ICD-10 Finland
Melaena
3.9
46.6
145
398
JJ5AT, ,
NOMESCO Finland
+∞
46.1
44
*
TK810
NOMESCO Finland
Hemofiltration
15.0
46.1
41
28
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
6.6
46.1
76
121
K83.1
ICD-10 Finland
Obstruction of bile duct
8.4
45.5
60
74
F10.25
ICD-10 Finland
Alcohol dependence continuous use
7.8
44.8
63
84
WX892
NOMESCO Finland
Monitored bed care
3.3
44.8
187
623
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.3
44.4
121
301
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
232.1
44.2
45
*
A10AE04
ATC
insulin glargine; parenteral
3.1
43.9
213
775
ZXD05
NOMESCO Finland
Urgent procedure
2.2
43.9
533
3002
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.6
43.7
85
159
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.4
43.7
74
121
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
43.5
223
837
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
43.5
245
968
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
10.1
42.9
49
50
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.1
42.7
123
319
N19
ICD-10 Finland
Unspecified kidney failure
4.6
42.7
105
241
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
8.2
41.5
56
71
C07AG02
ATC
carvedilol; oral
3.6
41.4
149
451
G93.4
ICD-10 Finland
Encephalopathy, unspecified
77.5
40.1
45
6
F10.24
ICD-10 Finland
Alcohol depence active use
7.7
40.1
57
77
N07BB01
ATC
disulfiram; oral
4.3
39.8
107
263
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
39.6
556
3288
WX882
NOMESCO Finland
High dependency care
5.1
39.5
85
174
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
205.6
39.0
40
*
R50.9
ICD-10 Finland
Fever, unspecified
2.5
39.0
283
1266
F05.9
ICD-10 Finland
Delirium, unspecified
6.2
38.2
66
110
N02AA05
ATC
oxycodone; systemic
2.4
38.0
341
1678
K74.3
ICD-10 Finland
Primary biliary cirrhosis
+∞
37.7
36
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.9
37.4
118
326
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.8
37.0
117
324
B18.2
ICD-10 Finland
Chronic viral hepatitis C
9.8
36.9
43
45
ZX120
NOMESCO Finland
Intravenous
2.9
36.5
193
734
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
9.4
35.8
43
47
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
7.3
35.8
53
75
A02BC02
ATC
pantoprazole; systemic
2.1
35.7
1034
7844
A41.8
ICD-10 Finland
Other specified sepsis
6.0
35.6
64
111
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
11.9
35.3
36
31
UJF32
NOMESCO Finland
Coloscopy
2.1
35.1
449
2540
Z51.5
ICD-10 Finland
Palliative care
3.0
34.9
173
634
H02AB04
ATC
methylprednisolone; systemic
2.5
34.6
261
1183
K70.2
ICD-10 Finland
Alcoholic fibrosis and sclerosis of liver
+∞
34.5
33
*
N02AX02
ATC
tramadol; systemic, rectal
2.0
34.1
701
4684
I50.0
ICD-10 Finland
Congestive heart failure
3.0
33.1
164
600
R11
ICD-10 Finland
Nausea and vomiting
2.9
32.7
166
616
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
5.3
32.5
67
132
57008
ICD-8 Finland
Acute and subacute necrosis of liver, Alii definiti
+∞
32.4
31
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
31.4
439
2547
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
31.4
210
897
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
31.4
30
*
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
6.6
31.3
51
80
R41.0
ICD-10 Finland
Disorientation, unspecified
4.4
31.1
81
194
Z2446
NOMESCO Finland
Social worker
3.1
30.7
137
472
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.8
30.5
98
274
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
8.5
30.1
39
47
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
8.5
30.1
39
47
H02AB06
ATC
prednisolone; systemic
1.9
29.8
724
5035
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.8
29.7
55
98
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
29.7
412
2378
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.2
29.5
127
428
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.2
29.4
61
121
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
29.2
454
2724
J01MA02
ATC
ciprofloxacin; systemic
1.9
29.2
617
4098
A28
ICPC
Limited function/disability NOS
2.2
29.1
300
1545
A46
ICD-10 Finland
Erysipelas
2.3
29.0
266
1306
ZX108
NOMESCO Finland
Inhalation
9.6
28.9
34
36
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
28.6
183
764
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
6.7
28.2
45
69
K29.6
ICD-10 Finland
Other gastritis
7.2
28.1
42
60
E87.6
ICD-10 Finland
Hypokalaemia
4.0
28.0
83
219
JN4BD
NOMESCO Finland
Extensive body CT
2.5
28.0
200
879
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
27.9
206
919
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.9
27.8
30
28
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.8
27.8
87
239
E87.5
ICD-10 Finland
Hyperkalaemia
5.5
27.0
53
100
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
6.2
26.8
46
76
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
26.7
519
3333
WX730
NOMESCO Finland
Conventional respirator
6.2
26.4
45
74
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
5.4
26.2
52
99
N05CF01
ATC
zopiclone; oral
1.9
26.2
505
3230
N05BA04
ATC
oxazepam; oral
1.9
26.1
403
2396
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
+∞
26.1
25
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
25.9
143
553
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.0
25.7
74
191
J01MA12
ATC
levofloxacin; systemic
2.0
25.6
318
1751
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
8.8
25.5
32
37
N05AH04
ATC
quetiapine; oral
2.1
25.4
275
1438
I81
ICD-10 Finland
Portal vein thrombosis
25.6
25.3
35
14
P16
ICPC
Acute alcohol abuse
5.8
25.3
47
84
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
25.3
140
542
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
25.3
271
1411
K76.6
ICD-10 Finland
Portal hypertension
+∞
25.1
24
*
UJD02
NOMESCO Finland
Gastroscopy
3.3
25.0
99
317
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.5
24.9
41
65
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
5.9
24.6
44
76
R4110
NOMESCO Finland
Physiotherapy
1.9
24.3
433
2688
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
24.3
70
181
JN4CD
NOMESCO Finland
Very extensive body CT
3.5
24.1
84
248
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
+∞
24.0
23
*
N06AX11
ATC
mirtazapine; oral
1.8
24.0
505
3300
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.4
23.8
89
275
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.8
23.4
43
76
Z3231
NOMESCO Finland
Registered nurse
1.9
23.3
425
2653
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
25.1
23.1
32
13
K86.1
ICD-10 Finland
Other chronic pancreatitis
7.8
23.0
32
42
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
7.0
23.0
35
51
R60.9
ICD-10 Finland
Oedema, unspecified
3.0
22.7
102
352
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.7
22.7
128
500
R94.5
ICD-10 Finland
Abnormal results of liver function studies
7.6
22.5
32
43
A10AE05
ATC
insulin detemir; parenteral
3.0
22.5
106
376
L04AA01
ATC
[U] ciclosporin
6.3
22.4
38
62
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
6.9
22.1
34
50
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
7.2
22.1
33
47
WX002
NOMESCO Finland
Sedation and analgesia
1.9
21.9
315
1815
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
21.8
316
1826
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.8
21.7
68
187
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
21.6
217
1098
XW000
NOMESCO Finland
Bone marrow biopsy
3.2
21.6
88
287
N18.8
ICD-10 Finland
Other chronic renal failure
4.3
21.5
56
134
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.3
21.4
184
874
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
21.1
261
1425
K74.0
ICD-10 Finland
Hepatic fibrosis
+∞
20.9
20
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
20.7
266
1471
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.7
20.7
116
451
Z3226
NOMESCO Finland
Physiotherapist
1.9
20.6
287
1633
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
5.1
20.5
43
86
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.4
20.4
74
224
ZXE90
NOMESCO Finland
More than 22 hours
8.5
20.2
26
31
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
6.5
20.1
33
52
L28
ICPC
Limited function/disability (L)
1.9
20.1
281
1599
K29.7
ICD-10 Finland
Gastritis, unspecified
3.4
20.0
75
232
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.9
19.9
59
156
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
5.6
19.7
37
67
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
7.8
19.6
27
35
S97
ICPC
Chronic ulcer skin
2.7
19.5
113
447
SPAT1262
SPAT
Handing over of treatment supplies
1.9
19.4
276
1578
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
19.3
333
2027
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.8
19.2
30
45
A98
ICPC
Health maint/preventive medicine
0.5
19.1
1143
12650
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.7
18.8
103
396
T90
ICPC
Diabetes non-insulin dependent
1.8
18.8
367
2316
Z72.1
ICD-10 Finland
Alcohol use
5.4
18.8
37
70
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
18.7
388
2490
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
18.7
103
397
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.1
18.7
79
263
SPAT1254
SPAT
Administration of medicine
2.0
18.7
229
1244
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
18.6
464
3134
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.3
18.5
37
71
N05BA01
ATC
diazepam; systemic, rectal
2.1
18.5
207
1088
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.1
18.4
50
124
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
13.7
18.3
31
23
R53
ICD-10 Finland
Malaise and fatigue
1.8
18.2
345
2155
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
18.2
219
1181
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
6.2
18.2
31
51
A10AC01
ATC
insulin (human); parenteral
2.4
18.1
132
583
M04AA01
ATC
allopurinol; systemic
2.0
17.9
221
1202
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
17.9
375
2410
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
5.4
17.8
35
66
V03AE01
ATC
polystyrene sulfonate; oral
5.4
17.8
35
66
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
17.8
228
1257
57309
ICD-8 Finland
Other diseases of liver, Unspecified
+∞
17.7
17
*
A07EA06
ATC
budesonide; oral, local oral
3.4
17.6
65
199
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.1
17.5
172
859
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.4
17.5
129
572
A40.8
ICD-10 Finland
Other streptococcal sepsis
6.1
17.4
30
50
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.8
17.2
53
144
J01FF01
ATC
clindamycin; systemic
1.7
17.1
393
2587
P19
ICPC
Drug abuse
13.4
17.0
29
22
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.3
16.8
34
66
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
6.3
16.8
28
45
K76.89
ICD-10 Finland
Other specified diseases of liver
+∞
16.7
16
*
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
35.5
16.7
21
6
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.1
16.3
67
220
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
16.2
252
1476
A02BC01
ATC
omeprazole; systemic
1.7
16.1
395
2638
B01AA03
ATC
warfarin; systemic
1.8
16.0
303
1885
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
16.0
93
369
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
15.9
496
3522
N03AX14
ATC
levetiracetam; systemic
3.4
15.9
56
167
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.5
15.7
101
420
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.7
15.7
50
139
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
3.8
15.6
47
126
3AC01, ,
NOMESCO Finland
6.3
15.5
26
42
A10BH05
ATC
linagliptin; oral
2.6
15.5
89
351
WX419
NOMESCO Finland
Other general anesthesy
6.5
15.4
25
39
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.1
15.3
65
217
E86
ICD-10 Finland
Volume depletion
3.5
15.3
52
151
JAH00
NOMESCO Finland
Laparotomy
3.3
15.2
57
177
N05CD07
ATC
temazepam; oral
2.0
15.1
188
1023
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.1
15.0
62
204
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.6
15.0
49
139
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
5.1
14.8
31
62
8000/3-C22.0
ICD-O-3
Neoplasm, malignant of liver
57.3
14.8
17
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
3.5
14.8
51
150
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
14.7
562
4169
N06AB04
ATC
citalopram; systemic
1.7
14.7
292
1838
Z94.0
ICD-10 Finland
Kidney transplant status
5.7
14.6
27
48
JCA20
NOMESCO Finland
Ligature of oesophageal varices
+∞
14.6
14
*
57300
ICD-8 Finland
Other diseases of liver, Hepatitis NUD
+∞
14.6
14
*
J94.8
ICD-10 Finland
Other specified pleural conditions
4.4
14.6
36
83
OAB43, ,
SPAT
0.4
14.5
93
1998
SPAT1265
SPAT
Breathalyser
5.5
14.5
28
52
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
5.5
14.5
28
52
C01AA05
ATC
digoxin; systemic
2.1
14.3
139
690
RS220, ,
NOMESCO Finland
4.9
14.3
31
64
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
4.7
14.3
33
72
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
13.5
14.2
24
18
C07AB07
ATC
bisoprolol; oral
1.5
14.1
709
5570
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
42.9
14.1
17
*
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
11.0
14.0
26
24
A10BH01
ATC
sitagliptin; oral
2.0
14.0
152
788
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
15.9
13.9
22
14
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.5
13.8
92
389
H02AB09
ATC
hydrocortisone; systemic
3.6
13.7
45
128
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
5.8
13.7
25
44
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.0
13.7
61
210
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.9
13.6
66
238
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.1
13.5
57
190
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
13.5
253
1563
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
13.5
121
583
R40.2
ICD-10 Finland
Coma, unspecified
6.1
13.4
23
38
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.7
13.4
42
116
N05BA02
ATC
chlordiazepoxide; systemic
3.3
13.3
49
150
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.2
13.3
115
545
K65.0
ICD-10 Finland
Acute peritonitis
5.4
13.3
26
49
N03AX16
ATC
[U] pregabalin
1.7
13.2
326
2169
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
15.2
13.1
21
14
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
15.2
13.1
21
14
R60.0
ICD-10 Finland
Localized oedema
1.9
13.1
179
1003
Z2221
NOMESCO Finland
Medical doctor
1.6
13.1
373
2569
N06AX16
ATC
venlafaxine; oral
1.9
13.1
187
1064
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.6
13.0
77
308
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
13.0
347
2352
N30.0
ICD-10 Finland
Acute cystitis
1.8
13.0
205
1203
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.3
12.9
48
148
B01AB05
ATC
enoxaparin; parenteral
1.6
12.9
442
3177
A07AA09
ATC
vancomycin; oral
4.8
12.9
29
62
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
3.2
12.8
50
159
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
5.4
12.8
25
47
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.6
12.8
77
311
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
12.8
206
1216
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
12.7
222
1341
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.9
12.6
59
209
198
Kela drug reimbursment
Sorafenib
32.3
12.6
16
5
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.8
12.6
62
226
57000
ICD-8 Finland
Acute and subacute necrosis of liver, Hepatitis acuta degenerativa
+∞
12.5
12
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
12.5
142
747
R06.0
ICD-10 Finland
Dyspnoea
1.6
12.5
377
2629
Z72.2
ICD-10 Finland
Drug use
20.2
12.5
18
9
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
12.4
312
2079
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.6
12.4
71
280
TJA10
NOMESCO Finland
Laparocentesis
14.5
12.3
20
14
E66.8
ICD-10 Finland
Other obesity
2.6
12.3
73
293
I42.0
ICD-10 Finland
Dilated cardiomyopathy
3.1
12.2
50
164
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
16.0
12.1
19
12
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.3
12.1
94
427
2BD01, ,
NOMESCO Finland
21.5
12.0
17
8
N05AH03
ATC
olanzapine; systemic
2.3
12.0
90
402
SPAT1216
SPAT
Assessment of functional ability
1.7
12.0
229
1418
A04
ICPC
Weakness/tiredness general
1.8
12.0
198
1176
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.5
12.0
41
120
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
11.9
110
2082
RS221, ,
NOMESCO Finland
4.1
11.9
32
79
K81.9
ICD-10 Finland
Cholecystitis, unspecified
5.4
11.8
23
43
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.3
11.8
30
71
C10AC01
ATC
colestyramine; oral
3.2
11.7
45
142
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
5.6
11.7
22
40
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
19.1
11.6
17
9
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
11.6
96
448
SPAT1255
SPAT
Intravenous administration of medicine
2.1
11.5
105
509
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.7
11.5
62
237
K71.1
ICD-10 Finland
Toxic liver disease with hepatic necrosis
+∞
11.5
11
*
WW408, ,
NOMESCO Finland
+∞
11.5
11
*
A10BB12
ATC
glimepiride; oral
2.1
11.4
111
551
R4190
NOMESCO Finland
Nutritional therapy
2.7
11.4
61
232
K77
ICPC
Heart failure
3.3
11.4
42
129
N06AB10
ATC
escitalopram; oral
1.7
11.4
249
1598
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.9
11.4
33
86
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.4
11.3
75
317
B01AB04
ATC
dalteparin; parenteral
2.4
11.3
79
342
SPAT1263
SPAT
Sampling
1.5
11.3
545
4186
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
10.6
11.3
21
20
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.5
11.3
68
275
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.7
11.3
35
96
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
11.3
327
2252
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.4
11.3
28
65
I50.1
ICD-10 Finland
Left ventricular failure
2.3
11.3
87
394
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
11.2
50
173
E000001, ,
ATC
1.7
11.1
256
1664
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
12.8
11.1
19
15
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
11.1
168
972
3A064, ,
NOMESCO Finland
14.0
11.0
18
13
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.7
11.0
57
214
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.6
10.9
65
261
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.5
10.9
66
267
N05BA12
ATC
alprazolam; oral
1.9
10.8
139
762
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.1
10.8
44
144
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
4.5
10.8
26
59
L04AA05
ATC
[U] tacrolimus
28.2
10.7
14
5
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
3.7
10.7
33
90
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
5.6
10.7
20
36
3A422, ,
NOMESCO Finland
60.5
10.6
12
*
N06AB06
ATC
sertraline; oral
1.9
10.6
144
804
D64.8
ICD-10 Finland
Other specified anaemias
3.5
10.6
36
105
I86.4
ICD-10 Finland
Gastric varices
+∞
10.4
10
*
PC2DT
NOMESCO Finland
Embolisation of lesion of liver
+∞
10.4
10
*
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
10.4
10
*
UJC12
NOMESCO Finland
Flexible oesophagoscopy
5.5
10.4
20
37
RS120, ,
NOMESCO Finland
16.2
10.4
16
10
K86.3
ICD-10 Finland
Pseudocyst of pancreas
12.1
10.4
18
15
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
10.3
155
893
UJK12
NOMESCO Finland
Peroral cholangioscopy
32.8
10.3
13
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
4.0
10.3
29
74
J96.0
ICD-10 Finland
Acute respiratory failure
4.0
10.3
29
74
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.1
10.3
96
469
E66.00
ICD-10 Finland
Metabolic syndrome
2.2
10.3
84
390
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
23.5
10.2
14
6
B03BA03
ATC
hydroxocobalamin; parenteral
2.2
10.2
86
404
A08
ICPC
Swelling
2.3
10.2
80
365
S01.0
ICD-10 Finland
Open wound of scalp
1.9
10.2
123
661
A10BA02
ATC
metformin; oral
1.5
10.1
399
2928
A11CC03
ATC
alfacalcidol; systemic
3.1
10.1
42
139
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
4.4
10.1
25
58
K08.3
ICD-10 Finland
Retained dental root
2.0
10.1
114
599
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
9.2
10.0
20
22
B03XA02
ATC
darbepoetin alfa; parenteral
3.1
10.0
42
140
K07
ICPC
Swollen ankles/oedema
2.3
10.0
73
323
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
40.4
10.0
12
*
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.5
9.9
33
95
ZXE00
NOMESCO Finland
One hour or less
1.5
9.9
512
3961
ZY010
NOMESCO Finland
Hospital outpatient
2.4
9.9
70
305
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
5.2
9.8
20
39
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
8.2
9.8
21
26
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
10.7
9.8
18
17
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.9
9.7
45
159
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
13.5
9.7
16
12
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
9.7
262
1770
D70.89
ICD-10 Finland
Neutropenic splenomegaly
4.2
9.7
25
60
R77.0
ICD-10 Finland
Abnormality of albumin
55.4
9.7
11
*
J01DB01
ATC
cefalexin; oral
1.5
9.6
1117
10015
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.8
9.6
48
177
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
11.5
9.6
17
15
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.4
9.5
66
285
A07EC02
ATC
mesalazine; oral, rectal
2.3
9.5
74
336
N05AA02
ATC
levomepromazine; systemic
2.5
9.5
61
255
K70
ICD-10 Finland
Alcoholic liver disease
100.7
9.4
10
*
B17.8
ICD-10 Finland
Other specified acute viral hepatitis
100.7
9.4
10
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
9.4
194
1224
A12BA01
ATC
potassium chloride; oral
2.3
9.4
71
319
F61.0
ICD-10 Finland
Mixed personality disorders
4.0
9.3
26
66
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
10.7
9.3
17
16
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.1
9.3
87
427
SPAT1240
SPAT
Therapeutic discussion
1.9
9.3
122
675
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.2
9.3
73
334
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.8
9.2
137
788
T89
ICPC
Diabetes insulin dependent
2.5
9.1
58
241
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.0
9.1
40
137
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.9
9.1
42
148
M10.9
ICD-10 Finland
Gout, unspecified
2.0
9.1
105
556
UJF92
NOMESCO Finland
Capsular endoscopy
3.3
9.1
34
106
PC2ET
NOMESCO Finland
Extensive embolisation of lesion of liver
36.9
9.0
11
*
SPAT1229
SPAT
Assessment of need for aid
1.9
9.0
110
594
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.1
9.0
80
385
NG4AA
NOMESCO Finland
Lower leg X-ray examination
2.6
9.0
52
207
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.2
8.9
34
107
JDA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in stomach or pylorus
24.2
8.9
12
5
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.7
8.9
45
167
JJA20
NOMESCO Finland
Open biopsy of liver
12.6
8.9
15
12
JN1AD
NOMESCO Finland
CT examination of upper part of abdomen
8.0
8.9
19
24
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.0
8.9
97
504
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
8.7
112
614
A02BC05
ATC
esomeprazole; systemic
1.4
8.7
523
4135
2BB01, ,
NOMESCO Finland
50.3
8.7
10
*
RD210, ,
NOMESCO Finland
3.4
8.7
30
89
WW200
NOMESCO Finland
Immunization
2.8
8.6
41
147
N05AB01
ATC
dixyrazine; systemic
4.0
8.6
24
61
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
8.6
479
3736
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
11.6
8.6
15
13
SPAT1247
SPAT
Outpatient detoxication and monitoring
11.6
8.6
15
13
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
7.0
8.6
20
29
R02
ICPC
Shortness of breath/dyspnoea
1.7
8.5
167
1038
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
9.0
8.5
17
19
GD1AD
NOMESCO Finland
Thorax CT examination
2.0
8.5
88
448
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
2.8
8.5
42
154
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.2
8.5
71
333
N06AX17
ATC
milnacipran; oral
4.2
8.5
22
53
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
8.5
86
435
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.1
8.4
81
401
OAA67, ,
SPAT
0.4
8.4
39
968
205
Kela drug reimbursment
Chronic hypertension
1.5
8.4
374
2798
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
3.4
8.4
29
86
L01BB02
ATC
mercaptopurine; oral
4.9
8.4
18
37
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
3.3
8.4
30
91
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
4.7
8.4
19
41
E0000UV, ,
ATC
1.4
8.4
514
4075
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.3
8.4
65
296
160
Kela drug reimbursment
exenatide
3.0
8.3
35
117
I85
ICD-10 Finland
Oesophageal varices
+∞
8.3
8
*
K75.2
ICD-10 Finland
Nonspecific reactive hepatitis
+∞
8.3
8
*
57308
ICD-8 Finland
Other diseases of liver, Alii definiti
+∞
8.3
8
*
5714B
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ACTIVA (HBSAG-)]
+∞
8.3
8
*
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
8.3
8
*
5CM18, ,
NOMESCO Finland
8.6
8.3
17
20
Z08
ICPC
Social welfare problem
3.9
8.3
24
63
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
8.3
246
1694
D07AC01
ATC
betamethasone; topical
1.4
8.2
453
3520
W19
ICD-10 Finland
Unspecified fall
1.8
8.2
133
784
A40.9
ICD-10 Finland
Streptococcal sepsis, unspecified
14.6
8.2
13
9
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.7
8.2
25
68
N06AB03
ATC
fluoxetine; oral
1.7
8.2
156
963
P29
ICPC
Psychological sympt/compl other
2.1
8.1
74
359
D07AD01
ATC
clobetasol; topical
1.6
8.1
204
1350
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
4.8
8.1
18
38
F41.00
ICD-10 Finland
Moderate panic disorder
4.0
8.1
22
55
XF612
NOMESCO Finland
Measurement of central venous pressure
17.3
8.1
12
7
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
9.0
8.0
16
18
WX704
NOMESCO Finland
Intubation
1.9
8.0
106
587
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.9
8.0
105
580
NB6AA
NOMESCO Finland
Humerus X-ray examination
3.0
8.0
35
120
N05AF03
ATC
chlorprothixene; systemic
2.9
8.0
37
131
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.1
7.9
32
105
F10.41
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol with seizures
13.1
7.9
13
10
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
13.1
7.9
13
10
L76
ICPC
Fracture: other
2.6
7.9
45
178
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.2
7.8
30
95
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.3
7.8
29
90
N06AB05
ATC
paroxetine; oral
2.1
7.8
74
365
E83.1
ICD-10 Finland
Disorders of iron metabolism
10.9
7.8
14
13
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.8
173
1111
F10.03
ICD-10 Finland
Alcohol-related acute intoxication with delirium
9.5
7.8
15
16
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
7.0
7.8
18
26
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
7.8
212
1430
S72.0
ICD-10 Finland
Fracture of neck of femur
2.2
7.8
64
299
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
7.7
117
676
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
7.7
120
699
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
15.1
7.7
12
8
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.9
7.7
35
123
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
7.7
117
678
H02AB07
ATC
prednisone; oral
1.6
7.7
178
1156
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.6
7.6
42
163
K50.8
ICD-10 Finland
Other Crohn disease
3.8
7.6
23
62
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.1
7.6
71
348
Z02.7
ICD-10 Finland
Issue of medical certificate
1.9
7.6
92
495
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
7.6
135
817
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
7.6
831
7196
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.6
491
3912
H26.3
ICD-10 Finland
Drug-induced cataract
6.2
7.5
19
31
K85.8
ICD-10 Finland
Other acute pancreatitis
6.2
7.5
19
31
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
4.1
7.5
20
49
JDA42
NOMESCO Finland
Other endoscopic haemostatic procedure in stomach or pylorus
8.9
7.5
15
17
D05AX52
ATC
calcipotriol, combinations; topical
2.1
7.5
70
343
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
7.5
314
2315
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
7.4
72
358
RS321, ,
NOMESCO Finland
80.5
7.4
8
*
474, ,
NOMESCO Finland
80.5
7.4
8
*
OAA62, ,
SPAT
0.2
7.3
5
307
ZXD35
NOMESCO Finland
Usual procedure
2.4
7.3
49
209
P03
ICPC
Feeling depressed
1.9
7.3
96
531
GBB00
NOMESCO Finland
Tracheostomy
3.6
7.3
23
64
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
3.0
7.3
32
110
F13.24
ICD-10 Finland
Addiction relationship caused by sedative and hypnotic active addiction
10.9
7.3
13
12
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
2.6
7.3
42
167
K72
ICD-10 Finland
Hepatic failure, not elsewhere classified
+∞
7.3
7
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
7.3
7
*
K76.1
ICD-10 Finland
Chronic passive congestion of liver
+∞
7.3
7
*
5700A
ICD-9 Finland
Acute and subacute necrosis of liver[NECROSIS HEPATIS TOXICA ACUTA, SINE COMATE HEPATICO]
+∞
7.3
7
*
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
9.4
7.3
14
15
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.7
7.3
125
750
C10AA07
ATC
rosuvastatin; oral
0.7
7.2
230
3195
A10AB04
ATC
insulin lispro; parenteral
2.5
7.2
45
186
B82
ICPC
Anaemia other/unspecified
2.5
7.2
42
168
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
4.0
7.2
20
51
K86.0
ICD-10 Finland
Alcohol-induced chronic pancreatitis
30.2
7.2
9
*
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
20.1
7.1
10
5
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
3.4
7.1
25
75
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.7
7.1
129
786
S42.0
ICD-10 Finland
Fracture of clavicle
2.5
7.1
44
182
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
10.1
7.0
13
13
K85
ICD-10 Finland
Acute pancreatitis
3.1
7.0
28
91
S76
ICPC
Skin infection other
2.0
7.0
73
374
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.0
7.0
74
381
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
7.0
173
1141
G41.9
ICD-10 Finland
Status epilepticus, unspecified
6.4
6.9
17
27
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
6.9
104
600
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
5.5
6.9
19
35
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
7.6
6.9
15
20
K73.80
ICD-10 Finland
Non-alcoholic fatty liver (NASH, Non Alcoholic Steatohepatitis)
13.8
6.9
11
8
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
13.8
6.9
11
8
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.1
6.9
27
87
N06AX26
ATC
vortioxetine; oral
1.9
6.9
82
440
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
6.9
93
520
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.8
6.9
95
535
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.5
6.9
23
67
C09AA05
ATC
ramipril; oral
1.4
6.8
345
2628
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.8
6.8
95
536
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.8
6.8
91
507
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
9.4
6.8
13
14
V03AE02
ATC
sevelamer; oral
9.4
6.8
13
14
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
2.9
6.8
30
104
N06AX03
ATC
mianserin; oral
2.1
6.7
64
317
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.3
6.7
24
73
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.8
6.6
94
533
W10
ICD-10 Finland
Fall on and from stairs and steps
2.0
6.6
72
374
TPX15
NOMESCO Finland
Removal of vascular injection port
7.8
6.6
14
18
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
7.8
6.6
14
18
ZY000
NOMESCO Finland
Hospital inpatient
3.6
6.6
21
59
SPAT1260
SPAT
Consultation of another employee
1.5
6.6
215
1506
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.8
6.6
98
564
F11.20
ICD-10 Finland
Addiction-induced dependence caused by opiates currently independent
12.3
6.6
11
9
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.8
6.5
19
50
JDA32
NOMESCO Finland
Endoscopic injection in stomach or pylorus
10.1
6.5
12
12
SPAT1272
SPAT
Drug screening
10.1
6.5
12
12
B81
ICPC
Anaemia vit B12/folate deficiency
2.2
6.5
52
240
I50
ICD-10 Finland
Heart failure
2.3
6.5
47
208
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.4
6.5
43
183
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.7
6.5
34
129
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.1
6.5
57
274
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
6.5
151
982
R60.1
ICD-10 Finland
Generalized oedema
5.7
6.5
17
30
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.2
6.4
51
235
K83.3
ICD-10 Finland
Fistula of bile duct
70.2
6.4
7
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.4
6.4
42
178
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.2
6.4
50
229
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
14.4
6.4
10
7
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.4
6.4
40
166
JKA20
NOMESCO Finland
Cholecystectomy
2.4
6.4
40
166
S29
ICPC
Skin symptom/complaint other
1.5
6.4
226
1610
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
4.1
6.4
17
42
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
6.6
6.3
15
23
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.1
6.3
61
304
ED1AA
NOMESCO Finland
Mandibular X-ray examination
5.5
6.3
17
31
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
5.5
6.3
17
31
K50.9
ICD-10 Finland
Crohn disease, unspecified
3.4
6.3
22
66
L30.3
ICD-10 Finland
Infective dermatitis
2.2
6.3
48
218
J01MA14
ATC
moxifloxacin; systemic
1.7
6.3
119
734
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
18.1
6.3
9
5
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
18.1
6.3
9
5
B17.1
ICD-10 Finland
Acute hepatitis C
18.1
6.3
9
5
GBB03
NOMESCO Finland
Percutaneous tracheostomy
+∞
6.3
6
*
K74
ICD-10 Finland
Fibrosis and cirrhosis of liver
+∞
6.3
6
*
Z944, K720,
ICD-10 Finland
+∞
6.3
6
*
JDA22
NOMESCO Finland
Endoscopic ligature of varices of stomach
26.8
6.2
8
*
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
26.8
6.2
8
*
H04AA01
ATC
glucagon; nasal, parenteral
2.9
6.2
28
98
N06AX21
ATC
duloxetine; oral
1.6
6.2
138
887
SPAT1227
SPAT
Substance abuse rehabilitation
6.3
6.2
15
24
A04AA01
ATC
ondansetron; systemic, rectal
1.8
6.2
98
576
S06.0
ICD-10 Finland
Concussion
1.6
6.1
135
865
R04.0
ICD-10 Finland
Epistaxis
1.7
6.1
104
623
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.7
6.1
31
116
P76
ICPC
Depressive disorder
1.9
6.1
68
357
742, ,
NOMESCO Finland
12.6
6.1
10
8
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
6.1
54
261
R06AE07
ATC
cetirizine; oral
1.3
6.1
511
4209
K90.0
ICD-10 Finland
Coeliac disease
2.5
6.1
37
152
D63.8
ICD-10 Finland
Anaemia in other chronic diseases classified elsewhere
8.6
6.1
12
14
WX004
NOMESCO Finland
Patient-controlled sedation
8.6
6.1
12
14
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
6.7
6.0
14
21
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
10.1
6.0
11
11
JFB00
NOMESCO Finland
Partial resection of small intestine
3.2
6.0
23
73
K51.8
ICD-10 Finland
Other ulcerative colitis
3.2
6.0
23
73
D10
ICPC
Vomiting
2.0
6.0
58
289
SPAT1211
SPAT
Application of soft bandage
1.7
6.0
107
649
N06AA09
ATC
amitriptyline; systemic
1.7
6.0
118
735

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
187
44
48.70
317.84
1.1
1.0
—
—
—
0
0
191
44
49.90
307.65
1.1
1.0
—
—
—
0
0
454
577
11.03
307.65
1.8
1.9
1.50
1.38
g/l
0.35
425
528
401
173
31.75
307.65
1.5
1.2
91.33
72.86
titre
0.33
45
14
532
204
40.79
307.65
8.4
1.8
48.74
30.65
umol/l
13.20
514
176
705
1015
12.66
307.65
5.8
1.9
0.16
0.22
g/l
42.00
637
946
488
750
9.33
307.65
2.8
2.9
12.36
10.45
g/l
8.25
461
684
176
50
39.97
284.85
2.3
1.1
—
—
—
0
0
224
129
20.38
280.58
1.2
1.1
—
—
—
0
0
227
136
19.63
279.03
1.2
1.1
—
—
—
0
0
199
96
23.90
269.15
1.2
1.1
1.68
1.46
g/l
4.87
182
87
569
1252
6.86
266.38
10.5
2.5
32.24
7.90
umol/l
21.14
532
1102
499
1054
6.72
241.13
1.7
1.6
—
—
—
0
0
497
1066
6.59
235.90
13.5
7.3
11.28
9.87
mmol/l
2.91
480
1014
536
1248
6.25
232.94
1.7
1.6
—
—
—
0
0
117
14
90.88
222.84
2.2
1.2
—
—
—
0
0
115
18
69.35
210.53
1.5
1.1
9.29
17.04
g/l
2.15
73
13
113
21
58.31
200.59
2.2
1.3
10188.26
5476.79
e6/l
0.28
61
14
126
40
34.43
196.57
1.1
1.1
294.40
296.46
mg/l
0.05
118
35
556
1594
5.05
184.88
9.9
5.7
1.08
1.04
mmol/l
1.67
531
1469
541
1533
5.05
182.15
3.3
2.6
28.42
22.43
%
7.34
470
1304
102
19
57.70
180.78
2.2
1.3
—
—
—
0
0
115
36
34.63
179.96
4.0
2.0
—
—
—
0
0
190
182
11.88
176.86
1.3
1.2
280.97
238.54
u/ml
0.79
128
106
554
1635
4.88
176.60
3.2
2.5
2.09
2.31
g/l
9.89
513
1511
498
1359
5.07
174.72
1.6
1.3
404.62
464.41
titre
0.41
130
272
868
3650
4.47
171.35
11.6
3.0
90.16
32.48
u/l
10.53
837
3470
594
1938
4.52
164.60
7.0
3.4
0.78
0.82
mmol/l
11.50
570
1821
566
1784
4.58
164.10
3.3
2.5
13.24
12.89
umol/l
0.41
536
1655
183
198
10.44
156.02
1.4
1.5
—
—
—
0
0
177
184
10.83
155.29
2.3
1.2
—
—
—
0
0
108
44
26.46
154.70
1.9
2.1
153.94
74.04
umol/l
0.82
49
25
209
279
8.59
151.19
1.3
1.2
—
—
—
0
0
1000
5041
4.22
144.14
14.7
4.6
31.07
35.40
g/l
70.61
962
4682
121
76
17.29
143.65
1.4
1.1
184.00
70.00
titre
0.72
15
12
163
180
10.08
136.52
1.4
1.5
124.04
110.51
u/ml
0.83
25
33
1098
6065
4.42
134.96
22.4
5.9
32.34
11.26
umol/l
37.50
1066
5761
802
3643
3.71
131.30
5.5
2.5
59.12
82.38
u/l
0.54
772
3372
210
330
7.28
131.11
5.7
2.6
2.62
3.70
g/l
14.93
202
313
752
3323
3.65
127.56
6.8
4.3
—
—
—
0
0
1034
5629
3.97
126.09
27.5
15.8
1.38
1.29
inr
1.96
290
1628
306
722
5.11
124.38
1.4
1.5
—
—
—
0
0
204
331
7.02
123.38
5.5
3.1
1.78
1.56
mg/l
2.43
195
303
259
540
5.63
121.11
1.9
1.9
1.11
1.57
g/l
9.57
197
470
85
39
23.10
115.98
32.3
28.4
128.08
128.45
ug/l
0.01
73
33
514
1868
3.72
115.96
3.9
2.1
32.16
29.87
s
8.73
500
1810
535
2041
3.58
111.33
1.9
1.5
4.08
2.39
g/l
23.86
449
1195
656
2936
3.27
103.82
16.5
3.7
69.86
88.86
%
45.70
645
2873
399
1343
3.73
99.16
3.1
2.6
2.49
1.77
%
10.70
359
1198
68
26
27.40
99.16
1.0
1.1
—
—
—
0
0
135
180
8.17
96.80
1.2
1.2
—
—
—
0
0
332
1004
4.00
96.19
3.2
2.7
85.56
69.53
e9/l
5.86
270
778
354
1135
3.81
94.10
6.6
3.5
5.42
5.84
kpa
10.68
337
1098
69
32
22.60
93.54
1.5
5.9
—
—
—
0
0
351
1128
3.79
92.88
6.7
3.5
1.28
1.91
mmol/l
1.77
274
909
634
2942
3.06
91.69
3.2
2.1
3.68
3.01
mg/l
5.64
572
2477
66
31
22.27
88.97
1.0
1.0
—
—
—
0
0
445
1710
3.32
88.62
3.4
2.0
—
—
—
0
0
65
30
22.64
88.23
1.0
1.1
—
—
—
0
0
94
89
11.23
87.22
1.5
1.1
—
—
—
0
0
227
564
4.59
84.95
6.7
3.9
23.29
24.02
mmol/l
2.25
220
550
194
437
4.98
81.76
3.1
3.4
82.67
3362.02
u/ml
0.82
171
375
303
996
3.59
76.30
17.4
9.2
—
—
—
0
0
947
5827
2.83
75.51
17.0
6.9
1.19
1.21
mmol/l
14.50
837
4949
307
1049
3.45
72.50
4.9
2.3
35.56
39.22
u/l
0.32
273
903
883
5318
2.71
72.14
15.3
6.3
1.18
1.21
mmol/l
18.34
843
4836
89
105
8.97
70.21
1.2
1.3
—
—
—
0
0
888
5409
2.68
70.12
11.0
6.2
—
—
—
0
0
91
111
8.68
69.91
2.3
2.5
—
—
—
0
0
864
5219
2.64
68.98
10.6
5.8
0.71
0.67
%
1.48
827
4853
884
5408
2.65
68.60
11.0
6.2
9.38
8.75
%
6.15
847
5047
880
5385
2.63
68.03
10.6
5.8
2.86
2.87
%
0.06
844
5019
804
4715
2.60
67.91
4.6
2.7
375.17
140.18
ug/l
6.22
766
4316
50
23
22.49
67.78
1.0
1.1
—
—
—
0
0
890
5526
2.60
65.91
10.8
6.0
25.01
27.34
%
7.56
853
5175
879
5446
2.58
65.06
10.1
5.8
58.52
57.53
%
1.46
844
5097
905
5733
2.56
63.11
10.3
5.7
0.04
0.04
e9/l
0.06
812
4943
900
5722
2.53
61.70
10.3
5.7
0.62
0.59
e9/l
1.48
805
4934
922
5933
2.54
61.49
10.8
5.9
0.18
0.19
e9/l
1.33
827
5203
292
1066
3.18
61.08
14.8
7.8
2.25
1.37
mmol/l
6.44
282
1035
912
5865
2.52
60.48
10.4
5.7
1.61
1.95
e9/l
6.73
828
5172
663
3732
2.44
58.54
4.8
2.5
—
—
—
0
0
71
79
9.40
58.49
2.2
1.3
0.60
1.29
promille
2.62
61
60
53
38
14.44
58.11
2.5
2.8
38850.94
39736.97
ug/l
0.10
53
38
309
1203
3.00
57.52
3.2
4.1
10.36
23.43
ug/l
0.87
265
992
1067
7535
2.61
55.45
12.5
2.9
161.07
48.22
u/l
34.54
1028
6991
90
143
6.65
54.71
1.6
1.8
0.82
0.88
g/l
0.12
67
108
337
1414
2.81
54.34
18.1
8.5
11.45
11.98
kpa
1.47
320
1351
337
1414
2.81
54.34
18.1
8.5
4.78
5.12
kpa
6.57
319
1350
160
424
4.12
54.19
3.4
2.2
24.73
21.56
s
6.89
149
387
368
1631
2.69
53.21
2.0
1.7
—
—
—
0
0
94
162
6.14
52.74
6.9
6.9
12.79
11.74
mg/l
0.96
85
147
333
1409
2.77
52.68
18.3
8.5
0.16
1.17
mmol/l
2.99
258
1117
606
3433
2.32
50.88
7.1
4.1
7.41
7.40
ph
1.04
126
662
967
6693
2.36
49.78
15.3
8.9
4.14
4.18
e9/l
0.21
882
5850
153
420
3.96
49.24
3.1
2.2
844.62
463.81
ug/l
0.72
141
393
305
1274
2.77
49.16
19.4
8.9
95.88
95.49
%
0.68
297
1232
170
506
3.68
48.67
3.2
1.9
3.71
2.01
ug/l
0.84
154
449
529
2872
2.33
48.60
4.7
2.4
—
—
—
0
0
223
800
3.12
47.31
6.0
3.5
7.43
7.41
ph
2.09
22
106
41
28
15.04
46.06
1.1
1.1
—
—
—
0
0
222
810
3.06
45.66
6.0
3.5
4.87
5.18
kpa
5.79
208
781
981
6981
2.27
45.00
14.6
5.0
7.33
6.74
mmol/l
7.68
950
6583
441
2279
2.35
44.80
2.1
1.7
1205.07
1197.21
nmol/l
0.06
345
1711
459
2423
2.31
44.29
3.7
2.8
505.82
550.72
mosm/kgh2o
4.61
413
2086
242
944
2.88
44.05
6.2
2.8
5.19
4.57
kpa
3.01
228
911
1164
9037
2.51
41.63
25.4
7.2
127.19
77.79
u/l
50.46
1139
8496
183
642
3.12
40.06
19.9
11.0
23.17
24.37
mmol/l
3.67
175
621
269
1161
2.62
39.97
21.6
9.4
111.11
121.32
g/l
10.52
262
1133
238
968
2.75
39.78
2.5
2.9
63.89
66.51
g/l
3.51
212
879
597
3627
2.10
39.54
4.5
3.2
143.38
90.04
e6/l
0.32
499
2838
248
1038
2.68
39.15
2.1
2.2
346.54
369.73
nmol/l
1.08
232
949
296
1355
2.49
38.79
2.2
1.7
—
—
—
0
0
806
5501
2.06
38.54
5.0
2.6
—
—
—
0
0
574
3476
2.08
37.97
3.9
3.2
—
—
—
0
0
451
2497
2.17
37.69
2.7
1.8
2.62
1.18
mg/l
8.81
390
1923
63
104
6.29
36.81
1.3
1.2
—
—
—
0
0
178
653
2.97
35.89
25.9
12.1
—
—
—
0
0
545
3325
2.03
34.56
4.3
3.1
1.09
0.44
e6/l
2.84
459
2568
88
209
4.42
34.19
1.5
1.3
50.51
63.56
mmol/l
2.03
61
171
92
229
4.22
33.63
3.1
3.3
1111.59
616.63
u/ml
0.23
82
212
163
592
2.98
33.38
6.8
3.6
—
—
—
0
0
445
2549
2.08
33.32
3.3
2.5
7.07
5.38
e6/l
1.25
409
2305
577
3627
1.99
33.32
2.8
2.2
277.20
226.96
u/l
0.58
553
3402
688
4633
1.93
32.06
3.5
2.2
72.04
77.42
nmol/l
4.52
638
4123
634
4160
1.94
31.90
5.4
3.7
88.82
121.28
e6/l
0.55
509
3029
207
872
2.60
31.89
4.9
3.8
0.67
0.67
%
0.01
137
293
524
3231
1.98
31.61
4.2
3.1
—
—
—
0
0
410
2320
2.07
31.44
1.4
1.2
3.60
1.63
u/ml
0.68
85
621
310
1577
2.23
31.26
1.4
1.2
—
—
—
0
0
218
962
2.49
30.40
5.3
4.0
0.72
0.95
%
1.02
143
344
703
4844
1.88
29.82
2.5
2.0
90.67
94.04
pmol/l
1.06
389
2535
142
509
2.99
29.68
7.5
3.8
24.31
24.97
mmol/l
1.33
134
479
194
828
2.55
28.96
12.6
5.6
—
—
—
0
0
350
1922
2.08
28.75
3.7
2.9
3.20
2.05
e6/l
1.29
222
1076
557
3595
1.90
28.65
4.5
3.1
2745.53
1456.56
ng/l
3.33
494
3077
506
3167
1.92
28.58
4.5
2.7
3764.60
5809.34
umol/l
0.55
450
2758
465
2831
1.95
28.52
2.0
1.6
18.61
20.44
nmol/l
2.04
417
2397
200
877
2.49
28.17
5.3
3.9
98.63
89.71
ng/l
0.55
176
773
220
1008
2.40
28.14
1.7
1.4
—
—
—
0
0
360
2048
2.01
26.57
3.4
2.7
1.27
1.03
e6/l
0.64
227
1199
200
911
2.39
25.81
5.4
4.1
0.02
0.11
%
3.17
125
293
34
13
26.74
24.92
3.4
1.2
—
—
—
0
0
178
783
2.45
24.77
21.3
10.3
1.48
1.35
%
1.25
178
777
103
340
3.19
24.75
1.5
1.5
214.63
292.23
ug/g
2.58
51
207
58
129
4.64
24.44
1.7
1.3
—
—
—
0
0
71
185
3.99
24.39
3.4
4.0
2.18
1.53
%
0.37
65
168
147
597
2.63
24.16
5.9
3.0
23.97
25.13
mmol/l
3.23
137
575
173
763
2.44
23.91
7.8
3.0
115.34
128.50
g/l
9.60
162
745
961
7616
1.79
22.95
6.5
4.4
5906.67
2188.02
e6/l
0.38
12
126
63
160
4.07
22.41
1.7
1.4
25.79
32.58
g/l
3.35
55
142
208
1022
2.21
22.30
3.4
3.0
323.82
214.47
ng/l
1.69
193
935
547
3729
1.75
22.05
4.1
3.1
7.05
7.74
mmol/l
3.26
480
3117
61
155
4.07
21.68
2.7
2.4
—
—
—
0
0
177
823
2.31
21.64
2.1
2.6
—
—
—
0
0
105
379
2.91
21.59
18.8
7.9
1.93
1.31
mmol/l
2.24
90
336
127
509
2.64
21.39
16.4
6.4
1.98
1.60
%
3.38
115
482
57
142
4.14
20.81
2.3
2.4
33.26
32.69
pg
0.39
57
142
111
422
2.77
20.72
3.5
3.3
0.41
0.22
g/l
1.42
66
174
82
266
3.21
20.27
3.7
4.2
—
—
—
0
0
179
860
2.24
20.19
5.3
4.1
0.01
0.47
%
0.69
102
242
33
53
6.35
19.78
3.9
4.8
313.48
71.44
mg/l
0.45
25
39
369
2302
1.81
19.76
5.5
3.9
240.71
428.35
ng/l
1.27
312
1840
122
502
2.56
19.46
17.0
6.4
0.90
0.89
%
0.16
111
476
220
1168
2.04
19.13
8.3
4.1
—
—
—
0
0
27
36
7.62
19.13
2.1
1.5
—
—
—
0
0
79
262
3.13
18.83
1.5
1.7
—
—
—
0
0
979
8019
1.69
18.49
6.6
4.2
—
—
—
0
0
52
133
4.02
18.34
1.4
1.4
273.51
278.66
mosm/kgh2o
0.72
41
96
55
147
3.85
18.26
1.8
1.3
1541.63
1789.34
e6/l
0.17
38
105
163
786
2.21
18.17
17.1
7.9
23.30
24.68
mmol/l
3.38
155
751
251
4087
0.53
18.08
3.2
2.9
—
—
—
0
0
53
140
3.89
17.89
4.2
4.5
—
—
—
0
0
78
267
3.03
17.62
7.2
2.9
—
—
—
0
0
51
134
3.91
17.34
4.9
1.9
—
—
—
0
0
40
88
4.65
17.11
1.4
1.3
0.49
0.33
g/l
1.58
26
61
40
88
4.65
17.11
1.4
1.3
7.71
6.58
g/l
0.79
26
61
40
88
4.65
17.11
1.4
1.3
2.84
2.72
g/l
0.14
26
61
91
347
2.73
16.88
4.9
3.5
—
—
—
0
0
244
1406
1.89
16.57
2.2
1.4
—
—
—
0
0
50
134
3.83
16.55
1.7
1.3
28390.77
125034.11
e6/l
1.12
30
81
426
2887
1.68
16.53
11.8
6.6
—
—
—
0
0
40
91
4.49
16.43
1.4
1.3
—
—
—
0
0
75
263
2.95
16.25
6.1
5.0
2.92
2.71
mmol/l
0.20
49
175
622
4648
1.60
16.18
5.4
3.8
74.94
61.95
ng/l
0.23
518
3345
36
77
4.77
15.93
1.1
1.1
—
—
—
0
0
78
285
2.84
15.69
1.9
3.8
—
—
—
0
0
38
87
4.46
15.49
4.2
2.2
39.89
4.99
umol/l
2.85
32
58
497
3551
1.61
15.42
3.6
3.2
558.25
291.30
mg/l
0.59
359
2276
519
3748
1.60
15.39
4.1
3.8
22.97
8.18
mg/mmol
2.61
367
2369
94
384
2.55
15.21
2.2
3.6
1.35
1.27
ratio
—
7
31
95
392
2.52
15.05
2.2
3.6
69.54
68.59
mg/l
0.02
75
321
95
394
2.51
14.89
2.2
3.6
43.05
54.76
mg/l
0.33
74
324
71
254
2.89
14.85
3.1
2.6
14.49
16.42
%
2.54
31
133
378
2549
1.65
14.67
1.8
1.7
571.09
31389707.57
pmol/l
2.36
322
2109
24
39
6.24
14.22
1.0
1.0
—
—
—
0
0
43
116
3.79
14.13
3.5
3.9
62.09
53.11
%
1.65
38
102
41
107
3.91
14.10
1.2
1.1
—
—
—
0
0
64
224
2.94
13.93
4.3
1.6
—
—
—
0
0
73
275
2.74
13.88
25.1
9.1
12.06
11.14
mmol/l
0.98
65
252
73
275
2.74
13.88
25.1
9.1
105.62
105.58
mmol/l
0.02
65
252
59
199
3.05
13.70
1.5
1.6
—
—
—
0
0
148
770
2.03
13.45
3.4
3.0
6.67
5.89
e9/l
0.17
120
617
44
130
3.46
12.67
1.8
1.5
—
—
—
0
0
58
204
2.92
12.54
5.0
2.1
—
—
—
0
0
62
229
2.78
12.26
2.9
2.6
—
—
—
0
0
70
278
2.60
12.03
3.2
3.2
0.87
0.87
nmol/l
0.02
58
220
41
120
3.49
11.99
1.8
1.3
—
—
—
0
0
525
3980
1.50
11.73
4.6
3.3
2.29
2.35
mmol/l
12.08
463
3477
150
828
1.91
11.46
1.2
1.2
—
—
—
0
0
187
1108
1.79
11.40
2.5
2.5
9.67
7.20
ug/l
0.83
158
976
646
5149
1.46
11.01
20.1
9.4
0.00
0.00
e9/l
0.52
548
4219
66
272
2.50
10.53
4.9
1.7
—
—
—
0
0
31
82
3.84
10.51
1.7
1.4
20.03
13.56
u/l
1.36
31
77
22
45
4.95
10.28
1.4
1.3
71.53
51.51
%
1.43
15
35
30
79
3.86
10.24
1.3
1.3
29.27
34.95
mmol/l
0.73
25
71
179
2809
0.59
10.12
2.6
3.0
0.74
0.75
ug/l
0.05
124
1842
62
253
2.52
10.11
2.3
2.2
115.22
131.84
g/l
5.59
46
190
30
81
3.76
9.90
6.9
3.8
—
—
—
0
0
42
141
3.04
9.90
1.3
1.3
—
—
—
0
0
39
127
3.13
9.68
1.0
1.1
—
—
—
0
0
158
940
1.76
9.46
6.0
3.8
1.20
1.23
mmol/l
5.33
150
818
67
295
2.33
9.28
4.8
1.7
—
—
—
0
0
983
8617
1.44
9.28
6.8
4.0
19.62
12.30
mm/h
25.39
931
7933
67
297
2.32
9.15
4.9
1.7
—
—
—
0
0
19
38
5.05
9.10
1.4
1.4
—
—
—
0
0
66
292
2.32
9.05
1.1
1.1
—
—
—
0
0
459
3530
1.44
8.99
5.2
3.9
—
—
—
0
0
66
297
2.28
8.71
4.9
1.7
—
—
—
0
0
38
130
2.98
8.70
1.4
1.1
—
—
—
0
0
39
970
0.39
8.47
1.1
1.4
—
—
—
0
0
1215
12888
0.63
8.46
58.7
21.4
4.08
4.50
e12/l
82.09
1184
12527
58
250
2.38
8.45
1.3
1.7
0.94
0.80
nmol/l
0.61
48
211
1215
12886
0.63
8.41
58.4
21.3
30.78
30.39
pg
7.74
1198
12686
1059
11536
0.69
8.34
5.5
4.5
4.26
4.60
mmol/l
20.20
978
10668
1216
12891
0.63
8.33
59.2
21.5
123.50
135.86
g/l
92.41
1197
12687
1084
11755
0.68
8.28
5.7
5.0
2.46
2.72
mmol/l
18.57
995
10795
1216
12886
0.64
8.20
58.4
21.3
92.55
91.21
fl
13.06
1198
12688
1215
12876
0.64
8.16
60.8
21.5
36.95
40.23
%
54.25
1112
12029
64
293
2.24
8.13
1.3
1.2
3.33
9.47
u/ml
0.68
12
39
1216
12883
0.64
8.13
58.6
21.4
210.35
246.36
e9/l
41.14
1186
12557
1052
11459
0.70
8.09
5.4
4.4
1.32
1.44
mmol/l
14.28
966
10505
110
616
1.85
8.05
1.4
1.2
—
—
—
0
0
1217
12887
0.64
8.02
58.6
21.4
6.99
6.76
e9/l
2.17
1187
12526
35
120
2.96
8.00
6.8
3.5
—
—
—
0
0
37
131
2.87
7.99
1.3
1.7
—
—
—
0
0
50
207
2.47
7.97
2.7
2.2
262.04
3693.81
u/l
1.79
20
81
94
504
1.93
7.86
7.8
4.7
—
—
—
0
0
403
3089
1.42
7.85
1.6
1.4
—
—
—
0
0
25
71
3.57
7.71
1.2
1.2
—
—
—
0
0
51
217
2.40
7.67
4.4
3.1
3.32
4.40
e9/l
3.07
51
217
63
294
2.20
7.66
4.5
1.7
—
—
—
0
0
62
288
2.20
7.62
1.2
1.2
2.14
2.67
u/ml
—
7
22
52
225
2.36
7.54
4.6
3.4
55.42
58.09
%
0.90
52
225
66
317
2.13
7.47
2.3
2.1
12.42
11.72
mg/l
0.24
61
289
189
1257
1.58
7.36
1.5
1.3
—
—
—
0
0
81
424
1.96
7.28
1.9
2.8
12.24
10.48
g/l
1.25
69
379
10
5
20.12
7.13
1.1
1.0
—
—
—
0
0
23
66
3.53
7.00
1.5
1.4
1.26
1.11
nmol/l
0.35
18
52
32
113
2.87
6.97
1.1
1.2
—
—
—
0
0
73
389
1.92
6.26
6.4
4.3
3.90
3.93
mmol/l
0.17
73
384
17
32
5.36
6.16
1.6
1.5
—
—
—
0
0
68
359
1.94
6.01
2.0
2.7
33.17
37.64
g/l
5.13
57
315
24
632
0.37
5.96
1.2
1.4
—
—
—
0
0
27
95
2.88
5.96
1.7
2.2
1.07
1.16
e9/l
0.22
21
87
15
26
5.82
5.84
1.6
1.3
23.80
24.45
%
—
10
20
10
9
11.18
5.79
1.4
1.0
—
—
—
0
0
20
60
3.37
5.73
5.4
3.1
3102.80
1448.77
u/ml
0.85
20
60
16
41
3.94
5.72
1.4
1.6
—
—
—
0
0
15
27
5.60
5.69
1.7
1.9
—
—
—
0
0
12
17
7.11
5.44
1.0
1.4
—
—
mmol/l
—
0
0
177
1243
1.48
5.35
2.6
2.2
219.86
137.52
ug/g
1.33
151
991
1030
11079
0.75
5.34
5.1
4.0
1.35
1.31
mmol/l
0.96
948
10086
33
137
2.44
5.32
1.3
1.2
—
—
—
0
0
20
65
3.11
5.07
1.5
2.9
9.82
9.77
mmol/l
0.02
20
65
26
99
2.66
5.00
1.2
1.4
1.13
1.37
nmol/l
0.50
26
86
21
71
2.99
4.99
3.9
2.8
—
—
—
0
0
202
1482
1.42
4.85
1.3
1.3
—
—
—
0
0
20
68
2.97
4.72
1.0
1.2
148.66
146.60
nmol/l
0.05
20
68
46
232
2.02
4.68
1.4
1.4
—
—
—
0
0
14
30
4.70
4.68
1.7
1.1
—
—
—
0
0
10
14
7.19
4.65
1.2
1.2
—
—
—
0
0
12
22
5.49
4.60
1.7
1.2
—
—
—
0
0
1067
11361
0.76
4.56
5.7
4.6
6.34
6.00
mmol/l
8.40
979
10301
14
32
4.41
4.44
14.9
7.1
—
—
—
0
0
15
37
4.09
4.41
1.1
2.1
—
—
—
0
0
51
273
1.90
4.40
1.4
1.3
296.78
200.26
miu/ml
0.52
11
125
20
71
2.84
4.39
1.8
2.4
448.93
473.34
e6/l
0.08
14
62
534
4577
1.27
4.33
4.8
3.4
5.81
5.81
ph
0.01
13
306
401
4775
0.78
4.33
4.0
4.9
2.52
2.85
ug/l
0.28
358
4270
36
171
2.13
4.31
1.9
2.7
—
—
—
0
0
49
261
1.91
4.30
1.4
1.5
544.02
604.90
e6/l
0.04
40
213
49
261
1.91
4.30
1.3
1.4
3.00
43.11
e6/l
1.09
37
207
21
504
0.41
4.29
1.9
1.7
—
—
—
0
0
36
174
2.10
4.13
1.1
1.1
20.34
113.40
iu/ml
—
5
40
10
17
5.91
4.13
2.1
1.2
—
—
—
0
0
21
80
2.65
4.07
2.3
3.0
39.00
40.70
%
—
9
40
528
4546
1.26
4.06
2.4
2.1
—
—
—
0
0
19
69
2.78
4.02
1.9
2.5
0.21
0.20
e9/l
0.09
14
62
14
43
3.28
3.91
1.5
1.2
—
—
—
0
0
23
94
2.47
3.89
3.5
1.9
9.91
11.40
%
0.82
23
94
10
19
5.29
3.83
2.0
1.5
—
—
—
0
0
7
8
8.79
3.77
3.0
2.4
—
—
—
0
0
6
5
12.04
3.76
3.7
3.0
4.52
4.40
mmol/l
—
6
5
96
640
1.54
3.76
2.7
3.4
4.09
4.50
pmol/l
2.31
78
565
27
122
2.24
3.68
1.6
2.3
—
—
—
0
0
11
25
4.43
3.62
15.2
7.8
—
—
—
0
0
11
25
4.43
3.62
2.4
1.9
43.33
259.09
e6/l
—
6
11
10
21
4.79
3.55
1.2
1.1
—
—
—
0
0
6
6
10.03
3.50
1.0
1.2
—
—
—
0
0
640
5694
1.22
3.49
5.3
3.6
0.00
0.00
estimate
0.50
144
1140
35
182
1.95
3.35
1.3
1.4
—
—
—
0
0
14
48
2.94
3.30
1.6
1.2
—
69.86
%
—
0
7
12
33
3.66
3.29
1.6
1.2
10.82
113.95
ug/l
—
6
13
33
170
1.96
3.25
1.3
1.2
3.95
6.44
u/ml
0.58
22
73
1192
12403
0.77
3.25
46.5
17.0
93.29
79.82
umol/l
10.53
1192
12398
39
213
1.85
3.24
1.7
1.3
90.38
42.38
u/l
0.65
31
180
23
104
2.23
3.16
1.0
1.4
—
33.57
—
0
7
87
1244
0.68
3.07
1.5
1.6
—
—
—
0
0
22
99
2.24
3.07
1.2
1.2
—
—
—
0
0
6
8
7.53
3.05
1.0
1.0
—
—
—
0
0
21
93
2.28
3.04
1.6
2.1
39.87
37.61
%
0.28
21
93
317
2650
1.25
3.04
5.0
3.6
—
—
—
0
0
76
509
1.52
2.97
1.2
1.2
—
—
—
0
0
8
17
4.73
2.92
9.9
9.1
9.94
6.12
mmol/l
—
8
17
908
9691
0.83
2.92
51.8
18.9
332.28
332.65
g/l
0.53
898
9619
10
276
0.36
2.89
1.4
1.7
—
—
—
0
0
25
122
2.07
2.88
1.3
1.5
—
—
—
0
0
22
102
2.17
2.87
2.0
2.2
708.00
647.27
ml
0.21
12
63
7
13
5.40
2.87
1.3
1.5
—
—
—
0
0
23
109
2.13
2.85
2.9
3.2
76.19
26.61
mg/l
0.52
17
81
23
110
2.11
2.79
1.6
1.5
0.15
0.34
nmol/l
2.49
18
85
133
1005
1.36
2.73
5.7
3.3
—
—
—
0
0
10
29
3.46
2.69
1.0
1.5
—
—
—
0
0
50
313
1.62
2.64
2.1
2.3
205.42
98.82
ug/min
0.67
28
183
628
5684
1.19
2.61
7.0
4.9
0.00
0.00
estimate
0.50
137
1068
45
275
1.66
2.61
1.3
1.4
8.37
9.25
u/l
0.18
34
223
35
201
1.76
2.53
3.9
3.0
—
—
—
0
0
17
75
2.28
2.51
1.2
1.5
—
—
—
0
0
633
5750
1.18
2.49
5.3
3.6
0.00
0.01
estimate
0.80
135
1034
14
309
0.45
2.44
1.1
1.2
—
—
—
0
0
6
12
5.02
2.40
2.0
3.7
—
—
—
0
0
51
330
1.57
2.38
1.5
1.2
—
—
—
0
0
5
8
6.27
2.37
1.0
1.3
—
—
—
0
0
24
125
1.94
2.36
2.1
2.5
2.23
1.76
g/24h
0.19
15
60
10
33
3.04
2.36
1.2
1.2
—
—
—
0
0
1169
12104
0.82
2.28
37.3
13.9
—
—
—
0
0
13
53
2.47
2.28
1.2
1.1
1.08
1.05
ratio
—
7
16
84
608
1.41
2.27
2.5
2.4
—
—
—
0
0
14
60
2.35
2.22
5.5
15.0
—
—
—
0
0
5
9
5.57
2.21
1.0
1.4
—
—
—
0
0
22
114
1.94
2.21
1.4
1.2
—
—
—
0
0
17
80
2.14
2.19
1.9
2.1
516.91
501.31
min
0.28
11
52
1201
12390
0.81
2.16
31.0
10.2
57.91
26.47
u/l
9.67
1183
11943
262
2230
1.21
2.10
3.6
3.1
2.47
2.45
mmol/l
2.43
217
1959
11
43
2.57
2.08
1.3
1.0
1717.91
1672.44
miu/ml
0.04
11
43
32
191
1.69
2.07
1.3
1.5
—
—
—
0
0
32
191
1.69
2.07
2.4
2.7
—
—
—
0
0
5
10
5.01
2.07
1.0
1.0
—
—
—
0
0
21
114
1.85
1.87
1.1
1.4
367101.33
100937.19
e6/l
0.36
12
78
43
285
1.52
1.86
1.3
1.8
27508.09
16648.45
e6/l
0.49
32
212
27
159
1.71
1.86
3.9
2.6
4.13
4.06
mmol/l
0.24
27
159
27
159
1.71
1.86
3.9
2.6
106.30
105.59
mmol/l
0.30
27
159
19
100
1.91
1.86
1.6
2.2
2.75
1.86
u/field
0.29
12
44
125
994
1.28
1.85
5.1
3.8
—
—
—
0
0
5
12
4.18
1.82
1.0
1.0
0.01
0.09
u/ml
—
5
12
18
94
1.93
1.80
1.8
1.4
—
—
—
0
0
16
80
2.01
1.80
3.2
1.1
—
—
—
0
0
12
54
2.23
1.74
1.5
1.9
—
—
—
0
0
29
457
0.63
1.73
1.0
1.1
—
—
—
0
0
1197
11601
1.19
1.69
41.4
14.6
24.69
25.42
mg/l
0.41
1124
9218
23
379
0.60
1.66
22.3
9.8
—
—
—
0
0
5
14
3.58
1.61
3.0
1.4
144.00
114.64
ng/l
—
5
14
45
312
1.46
1.60
6.2
4.7
—
—
—
0
0
347
3098
1.16
1.59
6.2
4.0
0.00
0.00
estimate
0.88
125
1030
6
21
2.86
1.50
1.0
2.0
18.42
17.37
umol/l
—
6
21
25
155
1.62
1.47
4.1
2.6
—
—
—
0
0
20
117
1.72
1.45
1.9
2.1
—
—
—
0
0
7
29
2.42
1.39
1.0
1.1
—
17.00
%
—
0
5
84
663
1.28
1.38
1.4
1.3
260.27
244.85
u/ml
0.06
79
605
14
75
1.88
1.34
1.2
2.7
—
—
—
0
0
53
393
1.36
1.34
1.6
1.7
—
—
—
0
0
283
2523
1.15
1.33
6.3
4.0
1.02
1.02
kg/l
0.27
53
356
135
1136
1.21
1.27
1.5
1.5
—
—
—
0
0
6
25
2.41
1.24
1.3
1.8
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
91
739
1.25
1.21
4.0
3.0
—
—
—
0
0
20
125
1.61
1.18
3.9
2.6
—
—
—
0
0
7
31
2.26
1.10
1.6
1.5
—
—
—
0
0
335
3080
1.11
0.97
4.9
3.3
—
—
—
0
0
15
92
1.64
0.97
1.2
1.1
—
—
—
0
0
23
330
0.69
0.97
1.3
1.1
—
—
—
0
0
7
37
1.90
0.94
1.4
1.9
—
—
—
0
0
30
217
1.39
0.94
1.4
1.6
—
—
—
0
0
6
28
2.15
0.91
1.0
1.1
—
—
—
0
0
6
28
2.15
0.91
1.0
1.1
—
—
—
0
0
6
28
2.15
0.91
1.0
1.1
—
—
—
0
0
1057
10836
0.91
0.89
8.3
5.8
40.90
40.08
mmol/mol
1.56
992
9975
71
841
0.84
0.75
1.3
1.4
—
—
—
0
0
9
53
1.70
0.75
1.1
1.3
6.10
6.33
mmol/l
—
9
53
11
67
1.65
0.75
1.4
3.0
—
—
—
0
0
28
369
0.75
0.75
1.1
1.1
—
—
—
0
0
5
24
2.09
0.74
2.0
1.1
—
—
—
0
0
62
516
1.21
0.73
2.4
2.8
—
—
—
0
0
26
194
1.35
0.71
1.5
1.4
—
—
—
0
0
7
40
1.75
0.71
2.7
2.9
—
—
—
0
0
18
127
1.42
0.68
1.3
1.6
—
—
—
0
0
96
838
1.16
0.67
1.5
1.4
—
—
—
0
0
7
43
1.63
0.67
2.7
2.3
—
—
—
0
0
13
86
1.52
0.66
2.2
1.5
101.85
81.93
umol/l
0.94
13
86
7
46
1.52
0.48
2.7
3.3
—
—
—
0
0
79
701
1.13
0.48
1.1
1.2
96.43
146.72
iu/ml
0.91
25
275
1039
10565
0.94
0.47
5.3
4.6
2.08
2.04
mu/l
0.11
966
9592
7
51
1.37
0.44
1.0
1.3
145.71
182.68
mmol/24h
—
7
51
329
3137
1.06
0.43
2.0
1.6
1.47
1.38
mmol/l
0.76
296
2608
9
128
0.70
0.43
5.9
2.9
13.68
13.22
%
—
9
128
820
8375
0.95
0.41
4.8
4.0
—
—
—
0
0
11
79
1.40
0.40
1.0
1.0
729.00
566.21
ng/l
—
6
43
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
16
124
1.29
0.38
1.4
1.3
—
—
nmol/l
—
0
0
15
192
0.78
0.38
1.3
1.1
—
12.94
—
0
10
9
68
1.33
0.37
1.1
1.0
—
—
—
0
0
107
986
1.09
0.36
2.0
2.2
13.20
12.81
nmol/l
0.17
96
875
200
1891
1.07
0.35
1.3
1.3
64.73
32.59
iu/ml
1.59
70
601
10
73
1.37
0.34
1.1
1.2
—
—
—
0
0
18
145
1.24
0.33
1.4
1.6
84.67
61.80
%
—
9
93
78
711
1.10
0.33
1.5
1.6
—
—
—
0
0
7
52
1.35
0.31
1.0
1.1
528.39
215.16
iu/ml
—
7
52
80
738
1.09
0.28
1.1
1.3
—
—
—
0
0
31
271
1.15
0.27
2.1
1.8
2.09
5.35
iu/l
—
8
89
64
586
1.10
0.27
5.2
3.7
—
—
—
0
0
12
95
1.27
0.26
2.8
1.8
—
—
—
0
0
16
132
1.21
0.25
1.5
1.3
—
—
—
0
0
18
152
1.19
0.23
1.7
1.2
—
—
—
0
0
14
116
1.21
0.22
1.3
1.2
—
—
—
0
0
39
353
1.11
0.21
1.5
1.4
24.91
28.30
iu/l
0.30
31
304
26
294
0.88
0.21
2.3
2.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
18
156
1.16
0.18
1.1
1.1
0.26
2.11
u/ml
—
10
82
21
237
0.88
0.17
1.3
1.3
—
—
—
0
0
7
62
1.13
0.17
1.3
1.4
7.07
8.54
ug/l
—
7
52
6
79
0.76
0.15
4.3
2.2
—
—
—
0
0
16
140
1.14
0.15
1.4
1.3
0.68
0.63
nmol/l
0.25
16
132
1207
12123
0.97
0.13
49.9
17.1
3.98
3.99
mmol/l
0.09
1183
11797
178
1822
0.97
0.11
1.3
1.2
11.95
11.67
u/ml
0.02
53
699
874
8685
1.02
0.10
4.4
3.8
14.80
14.86
pmol/l
0.27
801
7836
6
55
1.09
0.09
1.2
1.1
—
—
—
0
0
7
64
1.09
0.08
1.3
1.4
—
—
—
0
0
52
505
1.03
0.05
1.7
1.9
—
—
—
0
0
27
260
1.04
0.03
4.3
3.8
29.22
26.42
mg/l
0.16
18
166
997
9986
0.99
0.02
48.0
17.2
16.40
15.00
%
11.28
983
9801
1208
12090
0.99
0.01
49.8
17.0
138.19
139.68
mmol/l
48.22
1185
11781
14
136
1.03
0.00
1.1
1.0
1.98
2.02
u/ml
—
7
58
17
166
1.02
0.00
1.5
1.2
—
—
—
0
0
17
166
1.02
0.00
1.1
1.1
—
—
—
0
0
17
166
1.02
0.00
1.1
1.1
—
—
—
0
0
11
109
1.01
0.00
1.4
1.4
8.83
30.98
%
—
6
68
14
139
1.01
0.00
1.1
1.0
5.68
5.17
u/ml
—
7
68
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
67
0.90
-0.00
1.2
1.4
—
—
—
0
0
5
51
0.98
-0.00
1.4
1.1
—
316.68
—
0
13
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
1.71
—
0
7
5
56
0.89
-0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
330.60
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
9.39
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
1484.17
—
0
6
6
66
0.91
-0.00
3.3
7.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_HEPFAIL and mortality.

Females

Parameter HR [95% CI] p-value
K11_HEPFAIL 5.676 [4.64, 6.95] < 0.001
Birth year 0.999 [0.99, 1.01] 0.734

During the follow-up period (1.1.1998 — 31.12.2019), 1261 out of 2843 females with K11_HEPFAIL died.

Males

Parameter HR [95% CI] p-value
K11_HEPFAIL 8.309 [6.57, 10.51] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 1973 out of 3664 males with K11_HEPFAIL died.

Mortality risk

Mortality risk for people of age

years, who have K11_HEPFAIL.

N-year risk Females Males
1 0.605% 0.979%
5 3.398% 8.39%
10 9.095% 20.469%
15 16.851% 36.282%
20 27.438% 53.177%

Relationships between endpoints

Index endpoint: K11_HEPFAIL – Hepatic failure, not elsewhere classified

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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