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Hepatic failure, not elsewhere classified

DOID EFO Endpoint Browser PheWeb

K11_HEPFAIL

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K72
  • Hospital discharge: ICD-9 — 570
  • Hospital discharge: ICD-8 — 570
  • Hospital discharge: excluded ICD-8 — 57001
  • Cause of death: ICD-10 — K72
  • Cause of death: ICD-9 — 570
  • Cause of death: ICD-8 — 570
  • Cause of death: excluded ICD-8 — 57001

2 out of 7 registries used, show all original rules.

1299

4. Check minimum number of events

None

1299

5. Include endpoints

None

1299

6. Filter based on genotype QC (FinnGen only)

1299

Control definitions (FinnGen only)

Control exclude
K11_LIVER

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K70-K77
Name in latin
Insufficientia hepatis non alibi classificata

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13134 5721 7234
Only index persons 9949 4454 5495
Unadjusted period prevalence (%)
Whole population 0.19 0.16 0.20
Only index persons 0.19 0.16 0.21
Median age at first event (years)
Whole population 60.26 60.66 59.96
Only index persons 60.52 60.24 60.75

-FinnGen-

Key figures

All Female Male
Number of individuals 1299 597 702
Unadjusted period prevalence (%) 0.26 0.20 0.31
Median age at first event (years) 59.47 56.63 61.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1152
Matched controls
11521
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K72.9
ICD-10 Finland
Hepatic failure, unspecified
8753.2
323.0
516
*
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
+∞
323.0
473
*
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
2407.0
225.6
211
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
+∞
192.2
179
*
C03DA01
ATC
spironolactone; oral
9.4
175.5
411
639
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
174.5
163
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
10.8
168.2
357
461
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.2
147.8
421
853
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
41.3
147.1
185
53
R18
ICD-10 Finland
Ascites
45.8
145.5
179
46
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
245.9
129.8
131
6
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.4
114.9
583
2164
C03CA01
ATC
furosemide; systemic
4.1
105.0
587
2325
Z94.4
ICD-10 Finland
Liver transplant status
225.8
101.2
103
5
A06AD11
ATC
lactulose; oral
5.0
99.2
379
1022
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
28.2
90.0
124
49
JJC00
NOMESCO Finland
Allogenic transplantation of liver
926.5
88.9
86
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
+∞
88.7
84
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.3
82.8
368
1125
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
26.2
81.2
114
48
N17.9
ICD-10 Finland
Acute renal failure, unspecified
9.9
80.9
171
199
K70.4
ICD-10 Finland
Alcoholic hepatic failure
+∞
80.1
76
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
6.8
72.4
196
335
127
Kela drug reimbursment
Transplant complication
20.6
72.1
109
58
K70.1
ICD-10 Finland
Alcoholic hepatitis
697.3
67.7
66
*
K76.9
ICD-10 Finland
Liver disease, unspecified
180.4
65.7
68
*
A05AA02
ATC
ursodeoxycholic acid; oral
23.7
61.1
88
40
57009
ICD-8 Finland
Acute and subacute necrosis of liver, Unspecified
+∞
61.0
58
*
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
607.9
59.2
58
*
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
607.9
59.2
58
*
A07AA11
ATC
rifaximin; oral
596.8
58.2
57
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.9
57.9
174
336
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
46.4
57.4
70
16
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
56.6
307
1064
TK800
NOMESCO Finland
Hemodialysis
11.6
56.4
108
102
L04AA06
ATC
mycophenolic acid; systemic
16.2
54.7
90
60
K76.7
ICD-10 Finland
Hepatorenal syndrome
+∞
51.4
49
*
D64.9
ICD-10 Finland
Anaemia, unspecified
4.0
51.3
229
667
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
111.0
49.2
53
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
49.0
627
3693
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
31.2
48.9
65
22
K70.0
ICD-10 Finland
Alcoholic fatty liver
174.0
48.2
50
*
A41.9
ICD-10 Finland
Sepsis, unspecified
8.0
47.8
113
155
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
+∞
47.2
45
*
WX872
NOMESCO Finland
Intensive care
5.2
42.8
142
304
C07AA05
ATC
propranolol; systemic
2.9
41.1
290
1179
AA1AD
NOMESCO Finland
CT of head and brain
2.6
40.5
382
1849
JJ5AT
NOMESCO Finland
NA
411.2
40.3
40
*
L04AD01
ATC
ciclosporin; systemic
10.1
40.2
82
87
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
4.3
40.1
159
409
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
400.4
39.3
39
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
38.8
335
1533
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
24.6
38.2
54
23
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
35.7
37.5
48
14
A02BC02
ATC
pantoprazole; systemic
2.3
35.9
802
5799
K92.0
ICD-10 Finland
Haematemesis
8.0
34.5
80
106
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
22.2
33.7
49
23
L04AX01
ATC
azathioprine; systemic
5.8
33.5
99
184
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
33.2
194
683
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
32.9
198
712
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
+∞
32.4
31
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
5.4
32.1
101
202
UJK02
NOMESCO Finland
ERCP
8.0
31.6
73
96
K83.0
ICD-10 Finland
Cholangitis
11.9
31.3
58
51
N02AA05
ATC
oxycodone; systemic
2.7
30.8
238
1005
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.8
30.5
89
163
A10AE04
ATC
insulin glargine; parenteral
3.3
30.1
163
542
P15
ICPC
Chronic alcohol abuse
6.9
29.8
76
116
N02AX02
ATC
tramadol; systemic, rectal
2.1
29.7
548
3519
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
29.6
423
2437
WW500
NOMESCO Finland
Blood transfusion
4.9
29.5
101
222
JN3AD
NOMESCO Finland
Abdominal CT examination
3.6
29.4
143
437
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
29.3
187
696
R50.9
ICD-10 Finland
Fever, unspecified
2.8
29.3
215
876
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
11.5
29.3
55
50
D97
ICPC
Liver disease NOS
58.3
29.2
34
6
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
8.0
29.1
67
88
K74.3
ICD-10 Finland
Primary biliary cirrhosis
299.1
28.9
29
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
8.1
28.5
65
84
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
28.0
339
1800
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.8
27.9
124
351
WX892
NOMESCO Finland
Monitored bed care
3.4
27.7
143
457
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.4
27.6
86
170
G93.4
ICD-10 Finland
Encephalopathy, unspecified
48.4
27.5
33
7
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
8.1
27.5
63
82
R11
ICD-10 Finland
Nausea and vomiting
3.5
27.4
136
421
K70.2
ICD-10 Finland
Alcoholic fibrosis and sclerosis of liver
+∞
27.2
26
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.6
26.4
128
389
57008
ICD-8 Finland
Acute and subacute necrosis of liver, Alii definiti
+∞
26.1
25
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
6.4
26.1
70
115
K92.1
ICD-10 Finland
Melaena
4.0
26.0
108
287
N17.8
ICD-10 Finland
Other acute renal failure
11.6
25.8
48
43
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.3
25.1
96
236
JN4AD
NOMESCO Finland
Body CT examination
3.2
24.8
138
464
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.1
24.7
148
524
H02AB04
ATC
methylprednisolone; systemic
2.6
24.6
206
900
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.6
24.1
87
202
UJF32
NOMESCO Finland
Coloscopy
2.1
24.1
341
1918
F10.25
ICD-10 Finland
Alcohol dependence continuous use
9.0
24.0
51
59
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
8.8
23.7
51
60
JN4BD
NOMESCO Finland
Extensive body CT
2.7
23.5
176
721
N19
ICD-10 Finland
Unspecified kidney failure
4.9
23.4
79
171
103
Kela drug reimbursment
Diabetes, insulin-treated
2.1
23.4
354
2043
F10.20
ICD-10 Finland
Alcohol dependence currently independent
6.8
23.3
59
90
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.1
22.9
94
247
B18.2
ICD-10 Finland
Chronic viral hepatitis C
14.5
22.7
38
27
I50.9
ICD-10 Finland
Heart failure, unspecified
2.4
22.7
212
980
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.9
22.7
57
86
ZX120
NOMESCO Finland
Intravenous
2.8
22.3
155
604
J01MA12
ATC
levofloxacin; systemic
2.2
22.3
254
1290
WX882
NOMESCO Finland
High dependency care
5.4
22.1
68
133
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
+∞
21.9
21
*
J01MA02
ATC
ciprofloxacin; systemic
1.9
21.6
489
3262
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
8.5
21.5
47
57
K83.1
ICD-10 Finland
Obstruction of bile duct
10.3
21.4
42
42
N07BB01
ATC
disulfiram; oral
4.2
21.3
83
208
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
13.1
21.2
37
29
H02AB06
ATC
prednisolone; systemic
1.8
21.2
560
3925
N05AH04
ATC
quetiapine; oral
2.4
21.1
208
983
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
21.0
310
1759
N06AX11
ATC
mirtazapine; oral
1.9
21.0
370
2250
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
37.9
20.8
26
7
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
6.1
20.8
57
97
A28
ICPC
Limited function/disability NOS
2.3
20.6
217
1061
A09AA02
ATC
multienzymes (lipase, protease etc.)
6.8
20.4
52
80
N05CF01
ATC
zopiclone; oral
1.9
20.3
400
2526
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.7
20.2
147
589
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
19.7
175
782
A98
ICPC
Health maint/preventive medicine
0.5
19.3
873
9954
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.1
19.2
114
400
F10.24
ICD-10 Finland
Alcohol depence active use
8.3
19.1
42
52
TK810
NOMESCO Finland
Hemofiltration
13.0
19.0
33
26
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
18.8
398
2561
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.3
18.4
70
172
A41.8
ICD-10 Finland
Other specified sepsis
7.1
18.3
45
66
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
18.3
119
445
K76.6
ICD-10 Finland
Portal hypertension
+∞
17.7
17
*
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
17.7
17
*
JN4CD
NOMESCO Finland
Very extensive body CT
3.9
17.7
74
199
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.5
17.6
83
247
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
182.6
17.6
18
*
N05BA04
ATC
oxazepam; oral
1.9
17.5
290
1702
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
17.4
146
633
A46
ICD-10 Finland
Erysipelas
2.2
17.4
198
998
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
17.0
151
672
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.4
16.8
62
148
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
7.4
16.6
39
54
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.1
16.5
95
327
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
20.4
16.5
24
12
F05.9
ICD-10 Finland
Delirium, unspecified
5.6
16.5
48
89
WX002
NOMESCO Finland
Sedation and analgesia
2.0
16.4
246
1386
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
7.9
16.4
37
48
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.3
16.4
62
152
R41.0
ICD-10 Finland
Disorientation, unspecified
4.2
16.3
62
153
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
13.0
16.2
28
22
L28
ICPC
Limited function/disability (L)
2.1
16.2
203
1063
C07AG02
ATC
carvedilol; oral
2.9
16.0
98
352
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.3
15.9
59
142
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
12.4
15.9
28
23
P16
ICPC
Acute alcohol abuse
7.7
15.7
36
48
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
6.2
15.7
42
70
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
15.7
171
842
E87.6
ICD-10 Finland
Hypokalaemia
4.2
15.6
60
150
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
8.7
15.5
33
39
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.5
15.5
73
217
I50.0
ICD-10 Finland
Congestive heart failure
2.6
15.4
113
455
Z51.5
ICD-10 Finland
Palliative care
2.9
15.1
96
353
UJD02
NOMESCO Finland
Gastroscopy
3.3
15.1
79
255
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.9
15.1
93
336
A10AE05
ATC
insulin detemir; parenteral
3.0
15.1
87
301
SPAT1254
SPAT
Administration of medicine
2.1
15.0
183
947
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
7.1
14.9
36
52
R4110
NOMESCO Finland
Physiotherapy
1.8
14.8
318
2026
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
14.7
177
907
I81
ICD-10 Finland
Portal vein thrombosis
21.3
14.7
21
10
57309
ICD-8 Finland
Other diseases of liver, Unspecified
+∞
14.6
14
*
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.8
14.6
97
367
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
6.9
14.3
35
52
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
5.9
14.1
39
68
R53
ICD-10 Finland
Malaise and fatigue
1.9
14.0
236
1380
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
10.2
14.0
27
27
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
14.0
240
1412
A02BC01
ATC
omeprazole; systemic
1.7
13.9
322
2091
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
12.9
13.9
24
19
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.0
13.8
83
294
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
9.2
13.7
28
31
SPAT1262
SPAT
Handing over of treatment supplies
1.9
13.6
222
1281
K74.0
ICD-10 Finland
Hepatic fibrosis
+∞
13.6
13
*
57300
ICD-8 Finland
Other diseases of liver, Hepatitis NUD
+∞
13.6
13
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
13.4
312
2026
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.6
13.3
98
396
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
13.3
283
1789
N05CD07
ATC
temazepam; oral
2.1
13.2
162
836
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
13.1
124
568
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.9
13.1
36
63
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
7.5
13.0
30
41
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
13.0
195
1093
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
6.7
12.8
32
49
WX730
NOMESCO Finland
Conventional respirator
5.5
12.8
37
69
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
5.7
12.8
36
65
R94.5
ICD-10 Finland
Abnormal results of liver function studies
9.8
12.8
25
26
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
12.7
217
1268
Z72.1
ICD-10 Finland
Alcohol use
6.9
12.7
31
46
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.4
12.6
61
187
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.4
12.6
111
494
N18.8
ICD-10 Finland
Other chronic renal failure
4.0
12.5
50
130
JCA20
NOMESCO Finland
Ligature of oesophageal varices
+∞
12.5
12
*
K76.89
ICD-10 Finland
Other specified diseases of liver
+∞
12.5
12
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.9
12.4
34
59
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.4
12.4
106
461
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
12.2
187
1050
K29.7
ICD-10 Finland
Gastritis, unspecified
3.6
12.1
55
160
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
12.1
212
1251
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.2
12.1
134
664
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
27.0
12.1
16
6
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
27.0
12.1
16
6
2BD01
NOMESCO Finland
NA
21.5
12.0
17
8
P19
ICPC
Drug abuse
10.2
12.0
23
23
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
11.8
337
2305
N06AX16
ATC
venlafaxine; oral
2.1
11.8
146
754
RS220
NOMESCO Finland
NA
6.7
11.8
29
44
N05BA01
ATC
diazepam; systemic, rectal
2.0
11.8
162
877
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
11.7
84
334
N06AB10
ATC
escitalopram; oral
1.9
11.7
200
1168
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
19.1
11.6
17
9
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
19.1
11.6
17
9
SPAT1216
SPAT
Assessment of functional ability
1.9
11.6
179
1011
A07EA06
ATC
budesonide; oral, local oral
3.8
11.5
48
130
L04AA01
ATC
[U] ciclosporin; systemic
5.5
11.5
33
61
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
6.8
11.5
28
42
57000
ICD-8 Finland
Acute and subacute necrosis of liver, Hepatitis acuta degenerativa
+∞
11.5
11
*
WW408
NOMESCO Finland
NA
+∞
11.5
11
*
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
+∞
11.5
11
*
N30.0
ICD-10 Finland
Acute cystitis
2.0
11.5
148
780
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.5
11.4
52
152
A40.8
ICD-10 Finland
Other streptococcal sepsis
8.4
11.3
24
29
N06AB04
ATC
citalopram; systemic
1.8
11.3
232
1439
C07AB07
ATC
bisoprolol; oral
1.5
11.3
527
4072
E87.5
ICD-10 Finland
Hyperkalaemia
4.4
11.2
40
94
K29.6
ICD-10 Finland
Other gastritis
6.5
11.1
28
44
K86.1
ICD-10 Finland
Other chronic pancreatitis
8.1
11.1
24
30
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.7
11.1
48
135
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
7.2
11.1
26
37
T90
ICPC
Diabetes non-insulin dependent
1.7
11.1
259
1673
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.5
11.0
87
365
M04AA01
ATC
allopurinol; systemic
1.9
11.0
167
933
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.2
11.0
56
179
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
14.0
11.0
18
13
RS120
NOMESCO Finland
NA
43.7
10.9
13
*
L04AA05
ATC
[U] tacrolimus; systemic
43.7
10.9
13
*
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
43.7
10.9
13
*
V03AE01
ATC
polystyrene sulfonate; oral
5.7
10.8
30
54
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.4
10.7
88
378
XW000
NOMESCO Finland
Bone marrow biopsy
2.8
10.7
67
246
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
10.6
173
993
A10BH01
ATC
sitagliptin; oral
2.1
10.5
118
586
ZX108
NOMESCO Finland
Inhalation
7.4
10.5
24
33
8000/3-C22.0
ICD-O-3
Neoplasm, malignant of liver
111.0
10.4
11
*
R60.0
ICD-10 Finland
Localized oedema
2.0
10.4
132
687
K71.1
ICD-10 Finland
Toxic liver disease with hepatic necrosis
+∞
10.4
10
*
B01AA03
ATC
warfarin; systemic
1.7
10.4
244
1571
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
16.2
10.4
16
10
E86
ICD-10 Finland
Volume depletion
3.9
10.4
41
107
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.2
10.3
53
171
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
10.3
419
3113
N03AX14
ATC
levetiracetam; systemic
3.7
10.3
44
123
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.0
10.3
58
197
N05BA02
ATC
chlordiazepoxide; systemic
3.8
10.3
42
113
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
9.2
10.0
20
22
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
4.2
10.0
37
91
J01FF01
ATC
clindamycin; systemic
1.6
10.0
299
2056
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.0
10.0
39
101
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.5
10.0
46
137
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
4.4
9.9
35
82
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.8
9.9
24
36
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
9.9
348
2494
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.0
9.9
57
199
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.7
9.8
65
246
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
5.2
9.7
29
57
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
5.2
9.7
29
57
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.6
9.7
43
124
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.2
9.7
25
41
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
55.4
9.7
11
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
9.7
69
275
I50.1
ICD-10 Finland
Left ventricular failure
2.7
9.7
65
250
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.9
9.6
23
34
N03AX16
ATC
pregabalin; oral
1.6
9.6
254
1689
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
9.6
234
1523
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
6.4
9.6
24
38
K86.3
ICD-10 Finland
Pseudocyst of pancreas
11.5
9.6
17
15
N05AH03
ATC
olanzapine; systemic
2.6
9.6
71
288
2BB01
NOMESCO Finland
NA
100.8
9.4
10
*
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
9.4
9
*
5CM18
NOMESCO Finland
NA
12.5
9.4
16
13
S97
ICPC
Chronic ulcer skin
2.4
9.3
76
326
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.6
9.3
40
113
SPAT1265
SPAT
Breathalyser
6.1
9.2
24
40
A10BB12
ATC
glimepiride; oral
2.2
9.2
93
439
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
4.5
9.2
31
70
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
11.6
9.1
16
14
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.2
9.1
46
148
JJA20
NOMESCO Finland
Open biopsy of liver
15.7
9.0
14
9
H26.3
ICD-10 Finland
Drug-induced cataract
9.1
9.0
18
20
A10BH05
ATC
linagliptin; oral
2.6
9.0
65
261
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.7
8.9
58
220
JAH00
NOMESCO Finland
Laparotomy
3.1
8.8
46
151
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.0
8.8
120
647
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.2
8.7
44
141
3A422
NOMESCO Finland
NA
50.4
8.7
10
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.2
8.6
43
137
A04
ICPC
Weakness/tiredness general
1.9
8.6
134
758
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
5.0
8.5
26
53
K65.0
ICD-10 Finland
Acute peritonitis
6.5
8.5
21
33
F11.20
ICD-10 Finland
Addiction-induced dependence caused by opiates currently independent
27.7
8.5
11
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.9
8.5
33
86
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
6.0
8.5
22
37
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
8.4
91
446
R77.0
ICD-10 Finland
Abnormality of albumin
90.7
8.4
9
*
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
7.9
8.4
18
23
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
8.3
8
*
K70
ICD-10 Finland
Alcoholic liver disease
+∞
8.3
8
*
PC2DT
NOMESCO Finland
Embolisation of lesion of liver
+∞
8.3
8
*
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
6.3
8.3
21
34
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.5
8.3
37
108
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.0
8.3
45
152
R60.9
ICD-10 Finland
Oedema, unspecified
2.5
8.3
63
258
WX704
NOMESCO Finland
Intubation
2.2
8.2
82
387
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
8.2
624
5204
B03XA02
ATC
darbepoetin alfa; parenteral
4.0
8.2
31
79
N06AX17
ATC
milnacipran; oral
6.1
8.2
21
35
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.4
8.2
23
43
A10BA02
ATC
metformin; oral
1.5
8.2
297
2129
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
5.7
8.2
22
39
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
9.0
8.0
16
18
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
9.0
8.0
16
18
C08CA01
ATC
amlodipine; oral
1.5
8.0
379
2875
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
22.2
8.0
11
5
R06.0
ICD-10 Finland
Dyspnoea
1.6
8.0
257
1785
SPAT1240
SPAT
Therapeutic discussion
2.0
7.9
98
508
RS230
NOMESCO Finland
NA
13.1
7.9
13
10
N05BA12
ATC
alprazolam; oral
1.9
7.8
111
606
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
8.5
7.8
16
19
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
7.8
75
350
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
7.8
168
1050
SPAT1255
SPAT
Intravenous administration of medicine
2.1
7.8
83
403
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.4
7.7
19
30
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
5.6
7.7
21
38
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
7.7
178
1135
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.8
7.7
47
173
K85
ICD-10 Finland
Acute pancreatitis
4.2
7.6
27
65
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
25.2
7.6
10
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.4
7.6
34
101
3A064
NOMESCO Finland
NA
8.9
7.5
15
17
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
7.5
73
1310
SPAT1263
SPAT
Sampling
1.4
7.5
433
3406
Z94.0
ICD-10 Finland
Kidney transplant status
4.9
7.5
23
48
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
5.1
7.4
22
44
SPAT1229
SPAT
Assessment of need for aid
2.0
7.4
90
464
B17.8
ICD-10 Finland
Other specified acute viral hepatitis
80.6
7.4
8
*
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
4.6
7.4
24
53
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.7
7.4
48
183
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
4.4
7.4
25
58
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
7.3
103
561
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
10.9
7.3
13
12
5700A
ICD-9 Finland
Acute and subacute necrosis of liver[NECROSIS HEPATIS TOXICA ACUTA, SINE COMATE HEPATICO]
+∞
7.3
7
*
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.6
7.3
50
195
H02AB09
ATC
hydrocortisone; systemic
3.4
7.3
33
99
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
15.8
7.2
11
7
3AC01
NOMESCO Finland
NA
4.7
7.2
23
50
E66.00
ICD-10 Finland
Metabolic syndrome
2.4
7.2
59
253
K73.80
ICD-10 Finland
Non-alcoholic fatty liver (NASH, Non Alcoholic Steatohepatitis)
30.2
7.2
9
*
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
20.1
7.1
10
5
E66.8
ICD-10 Finland
Other obesity
2.5
7.1
51
206
J01MA14
ATC
moxifloxacin; systemic
1.9
7.1
94
502
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
7.1
180
1177
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
7.1
123
720
Y69
ICD-10 Finland
Unspecified misadventure during surgical and medical care
6.1
7.1
18
30
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
5.7
7.1
19
34
G41.9
ICD-10 Finland
Status epilepticus, unspecified
8.8
7.1
14
16
A07EC02
ATC
mesalazine; oral, rectal
2.3
7.0
61
270
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
7.0
237
1663
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
3.4
7.0
32
97
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.1
7.0
76
376
N06AX26
ATC
vortioxetine; oral
2.4
7.0
56
241
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
6.9
49
196
K50.9
ICD-10 Finland
Crohn disease, unspecified
5.5
6.9
19
35
E0000UV
ATC
NA
1.4
6.9
386
3009
WX419
NOMESCO Finland
Other general anesthesy
4.8
6.9
21
44
R4190
NOMESCO Finland
Nutritional therapy
2.8
6.8
41
150
PG1PT
NOMESCO Finland
Extensive endovascular embolisation for bleeding with radiological guidance not elsewhere classified
11.0
6.8
12
11
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
11.0
6.8
12
11
B01AB05
ATC
enoxaparin; parenteral
1.5
6.8
319
2402
TPX15
NOMESCO Finland
Removal of vascular injection port
9.4
6.8
13
14
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
9.4
6.8
13
14
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.6
6.8
47
184
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
16.8
6.7
10
6
F34.1
ICD-10 Finland
Dysthymia
2.9
6.7
39
138
J01DB01
ATC
cefalexin; oral
1.4
6.7
865
7801
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.2
6.7
67
320
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
6.7
207
1421
C01AA05
ATC
digoxin; systemic
1.9
6.7
100
560
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.0
6.6
35
118
F61.0
ICD-10 Finland
Mixed personality disorders
4.2
6.6
23
55
M10.9
ICD-10 Finland
Gout, unspecified
2.0
6.6
78
399
R40.2
ICD-10 Finland
Coma, unspecified
5.9
6.6
17
29
D07AC01
ATC
betamethasone; topical
1.4
6.6
347
2668
A07AA09
ATC
vancomycin; oral
4.1
6.6
24
60
F10.41
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol with seizures
12.3
6.6
11
9
198
Kela drug reimbursment
Sorafenib
12.3
6.6
11
9
SPAT1272
SPAT
Drug screening
12.3
6.6
11
9
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
6.5
282
2082
N05AA02
ATC
levomepromazine; systemic
2.4
6.5
52
220
A40.9
ICD-10 Finland
Streptococcal sepsis, unspecified
10.1
6.5
12
12
OAB43
SPAT
NA
0.4
6.5
35
761
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
6.5
113
663
E000001
ATC
NA
1.5
6.5
208
1440
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
5.7
6.5
17
30
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.5
6.4
28
82
G92
ICD-10 Finland
Toxic encephalopathy
70.2
6.4
7
*
D72
ICPC
Viral hepatitis
70.2
6.4
7
*
S01.0
ICD-10 Finland
Open wound of scalp
1.9
6.4
88
474
J96.0
ICD-10 Finland
Acute respiratory failure
4.7
6.4
20
43
Z72.2
ICD-10 Finland
Drug use
7.4
6.4
14
19
L30.3
ICD-10 Finland
Infective dermatitis
2.8
6.4
38
138
S72.0
ICD-10 Finland
Fracture of neck of femur
2.5
6.4
46
187
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
14.4
6.4
10
7
A08
ICPC
Swelling
2.4
6.4
49
206
JN1AD
NOMESCO Finland
CT examination of upper part of abdomen
8.2
6.3
13
16
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
6.0
6.3
16
27
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
6.0
6.3
16
27
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
5.5
6.3
17
31
GD1AD
NOMESCO Finland
Thorax CT examination
2.4
6.3
51
220
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
9.3
6.3
12
13
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
9.3
6.3
12
13
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
18.1
6.3
9
5
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.3
6.3
54
241
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
6.3
6
*
57308
ICD-8 Finland
Other diseases of liver, Alii definiti
+∞
6.3
6
*
Z944, K720
ICD-10 Finland
NA
+∞
6.3
6
*
N06AB06
ATC
sertraline; oral
1.8
6.2
100
572
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
3.5
6.2
27
79
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
26.8
6.2
8
*
K85.8
ICD-10 Finland
Other acute pancreatitis
7.1
6.2
14
20
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.2
6.2
59
277
C10AA07
ATC
rosuvastatin; oral
0.6
6.2
116
1766
SPAT1247
SPAT
Outpatient detoxication and monitoring
7.7
6.1
13
17
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.9
6.1
82
440
F93.89
ICD-10 Finland
Other childhood emotional disorders
12.6
6.1
10
8
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
12.6
6.1
10
8
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.1
6.1
63
307
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
4.9
6.1
18
37
A12BA01
ATC
potassium chloride; oral
2.2
6.0
58
273
K07
ICPC
Swollen ankles/oedema
2.3
6.0
52
231
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
6.7
6.0
14
21
TJA10
NOMESCO Finland
Laparocentesis
10.1
6.0
11
11
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
10.1
6.0
11
11
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
10.1
6.0
11
11
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.4
6.0
49
211
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
2.9
6.0
35
125
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.2
6.0
21
51
T89
ICPC
Diabetes insulin dependent
2.6
6.0
41
163

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
638
907
12.86
307.65
6.0
2.0
0.2
0.2
g/l
35.86
576
847
477
184
40.39
307.65
8.7
1.9
49.3
30.8
umol/l
10.95
438
150
356
166
29.16
307.65
1.5
1.2
79.8
81.5
titre
0.03
41
13
400
530
10.46
301.43
1.9
1.8
1.5
1.4
g/l
0.24
372
486
434
687
8.99
281.31
2.8
2.9
12.2
10.5
g/l
6.29
408
625
169
45
43.02
278.55
1.1
1.0
—
—
—
0
0
165
45
41.86
270.14
1.1
1.0
—
—
—
0
0
164
45
41.57
268.04
2.3
1.1
—
—
—
0
0
507
1122
6.77
235.47
11.1
2.5
32.4
8.0
umol/l
19.05
475
991
200
134
17.46
232.04
1.2
1.1
—
—
—
0
0
176
91
22.22
230.95
1.2
1.1
1.7
1.5
g/l
3.82
160
83
193
128
17.53
224.95
1.2
1.1
—
—
—
0
0
450
952
6.70
217.11
14.0
7.2
11.1
10.0
mmol/l
2.05
433
904
439
960
6.40
203.36
1.8
1.6
—
—
—
0
0
471
1145
5.88
193.53
1.7
1.6
—
—
—
0
0
99
11
97.34
190.10
2.3
1.3
—
—
—
0
0
101
16
68.36
184.41
1.6
1.1
9.4
17.0
g/l
1.67
65
11
99
18
59.45
176.35
2.3
1.3
10575.6
6222.9
e6/l
0.23
58
12
112
36
33.95
174.00
4.0
2.0
—
—
—
0
0
505
1439
5.11
169.62
10.2
5.6
1.1
1.0
mmol/l
1.50
480
1323
112
42
29.09
165.50
1.1
1.0
293.5
295.0
mg/l
0.03
105
37
174
163
12.17
164.51
1.3
1.2
284.0
235.7
u/ml
0.85
121
92
479
1388
4.88
155.87
3.4
2.6
28.7
22.5
%
6.84
412
1181
780
3275
4.46
154.24
12.2
3.0
94.1
32.7
u/l
9.70
751
3109
443
1224
4.97
152.57
1.6
1.3
383.5
452.5
titre
0.50
114
253
490
1481
4.71
150.43
3.2
2.5
2.1
2.3
g/l
8.51
451
1369
533
1736
4.51
148.02
7.4
3.4
0.8
0.8
mmol/l
9.60
511
1625
83
17
52.09
144.10
2.4
1.3
—
—
—
0
0
167
179
10.56
143.43
1.4
1.5
—
—
—
0
0
193
255
8.71
140.97
1.3
1.2
—
—
—
0
0
115
72
17.43
136.84
1.4
1.1
184.0
76.7
titre
—
15
9
498
1621
4.36
136.81
3.4
2.5
13.4
12.8
umol/l
0.77
469
1492
153
164
10.44
131.16
1.4
1.5
121.9
106.0
u/ml
1.01
23
30
94
42
24.05
129.89
1.9
2.1
128.2
82.3
umol/l
0.44
42
25
195
290
7.74
128.35
5.9
2.6
2.6
3.7
g/l
14.40
187
275
194
297
7.50
124.28
5.6
3.2
1.8
1.6
mg/l
2.24
185
272
885
4534
3.99
121.41
15.3
4.6
31.2
35.4
g/l
60.00
848
4203
150
175
9.56
120.51
2.4
1.3
—
—
—
0
0
84
35
25.59
119.08
31.9
30.1
128.1
135.3
ug/l
0.20
72
29
714
3282
3.61
113.42
5.5
2.5
58.7
58.1
u/l
0.11
683
3037
973
5469
4.10
112.61
23.0
5.9
32.4
11.3
umol/l
32.05
941
5194
275
657
5.04
110.06
1.5
1.5
—
—
—
0
0
660
3011
3.42
103.66
6.9
4.2
—
—
—
0
0
228
499
5.33
100.64
2.0
1.9
1.1
1.6
g/l
9.67
170
433
454
1689
3.59
97.94
4.1
2.1
32.1
29.8
s
7.62
441
1636
829
4441
3.40
97.86
20.2
9.5
1.4
1.3
inr
1.62
211
1266
63
23
28.74
93.32
1.0
1.1
—
—
—
0
0
471
1841
3.44
93.29
1.9
1.5
4.1
2.4
g/l
19.95
395
1073
66
29
23.92
91.44
1.5
5.8
—
—
—
0
0
585
2650
3.20
89.95
17.1
3.8
70.4
88.5
%
37.04
575
2593
63
27
24.47
88.08
1.0
1.0
—
—
—
0
0
62
27
24.06
86.14
1.0
1.1
—
—
—
0
0
352
1220
3.59
83.10
3.2
2.6
2.5
1.8
%
9.84
314
1088
310
1000
3.76
81.44
6.9
3.5
1.0
2.0
mmol/l
2.87
231
783
208
504
4.72
80.55
6.8
3.8
23.2
24.1
mmol/l
2.64
195
455
679
3512
2.96
79.90
9.6
5.8
—
—
—
0
0
309
1009
3.71
79.56
6.8
3.4
5.4
5.8
kpa
10.98
294
977
291
913
3.82
79.49
3.3
2.8
86.8
69.3
e9/l
6.06
241
711
84
78
11.44
78.97
1.5
1.1
—
—
—
0
0
116
168
7.48
77.29
1.2
1.2
—
—
—
0
0
87
90
10.29
75.88
1.2
1.3
—
—
—
0
0
89
96
9.88
75.30
2.3
2.5
—
—
—
0
0
558
2666
2.92
74.94
3.2
2.1
3.7
3.0
mg/l
4.49
503
2250
390
1542
3.19
73.29
3.5
2.0
—
—
—
0
0
174
401
4.86
71.32
3.1
3.4
54.2
3677.0
u/ml
0.83
153
342
363
1398
3.22
71.07
22.3
26.7
1.5
1.4
inr
0.51
44
185
48
20
24.88
67.62
1.0
1.1
—
—
—
0
0
265
888
3.49
64.54
18.5
9.2
—
—
—
0
0
837
5250
2.67
61.61
17.5
6.9
1.2
1.2
mmol/l
12.62
736
4428
270
949
3.33
60.65
4.6
2.4
35.4
40.5
u/l
0.42
243
816
770
4694
2.57
59.24
10.8
5.9
0.7
0.7
%
0.92
740
4367
781
4798
2.57
59.03
15.9
6.3
1.2
1.2
mmol/l
16.65
743
4333
785
4858
2.56
58.03
11.2
6.1
9.4
8.7
%
6.36
753
4535
782
4839
2.55
57.69
10.8
5.9
2.8
2.9
%
0.17
751
4492
791
4963
2.52
55.97
10.9
6.0
24.9
27.4
%
7.67
759
4611
780
4882
2.50
55.18
10.3
5.8
58.6
57.5
%
1.65
750
4556
707
4245
2.46
54.64
4.7
2.7
394.1
138.7
ug/l
5.81
675
3883
804
5154
2.47
53.16
10.6
5.7
0.0
0.0
e9/l
0.36
723
4435
146
370
4.32
52.64
3.5
2.1
24.9
21.5
s
7.08
136
335
798
5135
2.44
51.75
10.5
5.7
0.6
0.6
e9/l
1.65
718
4412
818
5333
2.44
51.33
11.1
6.0
0.2
0.2
e9/l
1.09
736
4678
810
5262
2.43
51.17
10.6
5.8
1.6
1.9
e9/l
5.90
735
4610
253
942
3.09
50.94
15.8
7.8
2.3
1.4
mmol/l
5.63
240
899
593
3372
2.40
50.66
4.9
2.5
—
—
—
0
0
88
148
6.31
50.66
7.0
6.9
12.7
11.7
mg/l
0.75
79
135
82
130
6.67
49.99
1.7
1.8
0.9
0.9
g/l
0.10
61
97
301
1263
2.80
48.55
19.0
8.5
4.8
5.1
kpa
6.01
284
1206
301
1263
2.80
48.55
19.0
8.5
11.5
12.0
kpa
1.24
285
1208
39
22
18.25
48.25
1.1
1.1
—
—
—
0
0
33
13
26.02
47.22
3.5
1.2
—
—
—
0
0
297
1258
2.76
46.89
19.2
8.6
0.2
1.3
mmol/l
3.11
229
984
331
1483
2.65
46.75
1.9
1.7
—
—
—
0
0
271
1097
2.86
46.62
3.1
4.1
6.6
25.1
ug/l
1.55
231
903
948
6770
2.48
46.01
12.9
2.9
153.9
48.4
u/l
34.09
912
6282
61
77
8.26
45.47
2.3
1.3
0.6
1.2
promille
1.97
51
58
272
1130
2.78
44.37
20.4
9.0
96.0
95.6
%
0.61
264
1093
137
382
3.89
43.15
3.3
2.2
918.5
493.5
ug/l
0.73
126
359
538
3097
2.26
42.80
7.2
4.0
7.4
7.4
ph
1.54
113
592
857
6001
2.26
41.24
15.2
9.0
4.2
4.2
e9/l
0.04
788
5240
467
2582
2.26
40.49
4.8
2.4
—
—
—
0
0
399
2065
2.35
40.47
2.1
1.8
1225.8
1194.1
nmol/l
0.25
311
1559
147
462
3.46
38.65
3.4
1.9
3.5
2.1
ug/l
0.59
131
408
195
726
2.98
38.64
6.3
3.6
7.4
7.4
ph
1.85
18
96
406
2162
2.28
38.14
3.6
2.7
512.3
559.0
mosm/kgh2o
4.35
367
1842
226
922
2.76
37.73
2.2
2.2
336.0
371.7
nmol/l
1.98
210
844
194
735
2.93
37.18
6.4
3.6
4.9
5.2
kpa
5.20
179
689
270
1217
2.54
36.79
2.2
1.7
—
—
—
0
0
869
6271
2.17
36.62
15.2
5.0
7.3
6.7
mmol/l
6.32
839
5917
163
568
3.14
36.15
20.9
11.1
23.3
24.5
mmol/l
3.35
154
530
238
1030
2.60
35.17
22.9
9.5
110.4
121.2
g/l
10.54
231
998
208
847
2.73
34.68
6.6
2.8
5.3
4.5
kpa
3.48
196
817
80
176
4.78
34.23
1.5
1.3
52.4
64.3
mmol/l
1.56
55
148
1031
8120
2.31
32.67
25.9
7.2
127.0
78.1
u/l
45.06
1008
7619
159
580
2.98
32.45
27.7
12.3
—
—
—
0
0
208
880
2.62
32.00
2.4
2.9
63.9
66.6
g/l
3.30
182
797
712
4934
1.98
31.40
7.6
4.1
—
—
—
0
0
397
2247
2.10
30.90
2.8
1.7
2.6
1.2
mg/l
7.73
342
1739
54
94
5.95
29.93
1.3
1.2
—
—
—
0
0
82
207
4.16
29.46
2.9
3.3
1230.2
665.6
u/ml
0.24
73
193
495
3091
1.97
28.93
4.0
3.2
—
—
—
0
0
518
3294
1.95
28.63
4.6
3.2
156.1
91.0
e6/l
0.36
444
2574
179
741
2.64
28.62
13.0
5.7
—
—
—
0
0
143
540
2.85
27.26
7.3
3.7
—
—
—
0
0
183
793
2.52
26.54
5.3
3.8
99.0
89.2
ng/l
0.58
162
698
181
781
2.53
26.49
5.0
3.9
0.5
0.6
%
0.24
66
194
609
4171
1.87
26.13
3.5
2.2
72.8
77.2
nmol/l
2.86
561
3700
199
906
2.41
25.90
1.7
1.4
—
—
—
0
0
390
2314
1.98
25.87
3.3
2.5
7.5
5.1
e6/l
1.83
357
2043
455
2845
1.92
25.84
4.6
2.7
4142.1
6079.6
umol/l
0.45
405
2449
192
863
2.44
25.70
5.4
4.0
0.6
0.9
%
1.27
93
259
502
3275
1.87
24.77
2.9
2.2
293.8
233.6
u/l
0.62
483
3076
359
2097
1.98
24.74
1.4
1.2
3.9
1.7
u/ml
0.68
77
562
266
1394
2.14
24.64
1.4
1.2
—
—
—
0
0
471
3020
1.88
24.47
4.4
3.1
1.0
0.4
e6/l
2.22
402
2307
124
464
2.85
23.98
8.1
4.0
24.5
25.0
mmol/l
0.72
116
437
455
2924
1.86
23.21
4.3
3.0
—
—
—
0
0
157
678
2.50
22.81
23.1
10.6
0.7
0.7
%
0.53
157
673
65
167
4.04
22.80
3.5
4.1
1.0
1.5
%
0.60
48
140
551
3781
1.79
22.47
5.4
3.7
90.5
119.0
e6/l
0.43
453
2753
306
1742
1.99
22.42
3.7
2.9
3.3
2.0
e6/l
1.34
206
968
176
816
2.34
21.81
5.6
4.1
0.0
0.1
%
2.12
89
238
51
114
4.62
21.39
1.4
1.5
274.2
278.4
mosm/kgh2o
0.54
40
82
96
332
3.04
21.35
19.4
8.0
1.9
1.3
mmol/l
1.97
82
295
154
683
2.42
21.07
23.0
10.5
1.5
1.4
%
0.87
154
678
51
116
4.54
20.94
1.7
1.3
—
—
—
0
0
91
311
3.07
20.66
1.5
1.5
217.2
293.4
ug/g
2.24
45
184
611
4396
1.74
20.57
2.5
2.0
90.8
94.1
pmol/l
0.92
335
2299
56
145
3.99
19.44
1.7
1.4
25.3
31.8
g/l
3.12
50
130
115
461
2.64
19.42
17.1
6.3
2.0
1.6
%
3.03
103
437
476
3241
1.74
19.15
4.5
3.1
2460.6
1468.2
ng/l
2.96
420
2782
73
229
3.32
19.10
3.7
4.0
—
—
—
0
0
183
918
2.16
18.62
3.6
3.0
343.5
218.2
ng/l
1.75
170
843
214
3653
0.50
18.55
3.1
2.9
—
—
—
0
0
31
50
6.33
18.52
4.1
2.9
336.7
72.4
mg/l
0.45
23
37
124
530
2.48
18.32
6.0
3.0
24.1
25.1
mmol/l
2.27
115
514
306
1851
1.85
18.23
3.5
2.7
1.2
1.0
e6/l
0.41
204
1073
146
676
2.31
18.04
8.5
3.0
114.1
128.1
g/l
9.15
136
662
156
746
2.24
17.84
2.0
2.7
—
—
—
0
0
49
123
4.10
17.75
5.0
2.0
—
—
—
0
0
50
128
4.02
17.64
4.3
4.5
—
—
—
0
0
87
318
2.86
17.52
5.4
3.7
—
—
—
0
0
391
2572
1.74
17.46
1.9
1.6
18.6
20.5
nmol/l
1.80
350
2165
24
31
7.87
17.46
2.2
1.3
—
—
—
0
0
481
3349
1.69
17.45
4.1
3.1
7.0
7.7
mmol/l
3.10
422
2777
110
455
2.55
17.41
17.7
6.4
0.9
0.9
%
0.24
99
431
100
395
2.66
17.37
3.5
3.2
0.3
0.2
g/l
1.43
58
164
147
703
2.23
16.79
17.9
8.0
23.3
24.7
mmol/l
3.16
139
662
197
1060
2.01
16.53
8.0
4.3
—
—
—
0
0
850
6910
1.67
16.40
6.7
4.4
6443.5
2380.8
e6/l
0.38
11
115
37
81
4.67
15.94
1.4
1.3
—
—
—
0
0
70
239
3.04
15.93
7.6
2.9
—
—
—
0
0
69
234
3.06
15.88
6.3
4.8
3.0
2.7
mmol/l
0.31
45
157
36
78
4.72
15.70
1.4
1.3
7.6
6.5
g/l
0.74
24
53
36
78
4.72
15.70
1.4
1.3
2.9
2.7
g/l
0.25
24
53
36
78
4.72
15.70
1.4
1.3
0.5
0.3
g/l
1.64
24
53
48
131
3.77
15.51
2.3
2.4
33.2
32.8
pg
0.20
48
131
322
2068
1.74
15.36
5.4
3.9
264.6
413.5
ng/l
0.81
271
1653
48
133
3.71
15.18
1.9
1.3
1510.4
1660.1
e6/l
0.09
33
94
45
120
3.85
15.03
1.7
1.3
29508.3
79447.1
e6/l
0.49
27
72
152
769
2.11
15.02
5.5
4.2
0.0
0.5
%
0.68
73
204
384
2610
1.67
14.76
12.0
6.7
—
—
—
0
0
218
1259
1.88
14.75
2.3
1.4
—
—
—
0
0
35
81
4.41
14.10
4.3
2.2
40.0
5.2
umol/l
2.56
30
52
71
263
2.80
13.97
4.6
2.8
8.6
8.1
kpa
1.43
66
243
66
235
2.91
13.96
1.4
1.7
—
—
—
0
0
38
95
4.09
13.87
1.2
1.1
—
—
—
0
0
68
250
2.82
13.57
25.6
9.0
106.0
105.4
mmol/l
0.34
60
229
68
250
2.82
13.57
25.5
9.0
12.2
11.1
mmol/l
1.17
60
229
60
206
3.01
13.54
4.5
1.6
—
—
—
0
0
74
287
2.67
13.34
6.1
4.3
7.4
7.4
ph
1.09
68
231
63
227
2.87
13.05
3.0
2.5
14.5
16.3
%
1.88
26
117
39
105
3.80
12.88
3.7
3.8
58.7
52.3
%
0.70
22
77
550
4179
1.55
12.85
5.4
3.8
78.3
63.3
ng/l
0.23
452
3001
67
252
2.75
12.82
2.0
3.8
—
—
—
0
0
862
7233
1.57
12.78
6.8
4.2
—
—
—
0
0
53
187
2.91
11.43
5.4
2.2
—
—
—
0
0
79
345
2.37
11.14
1.9
3.7
74.6
70.9
mg/l
0.06
62
280
78
339
2.38
11.12
1.9
3.7
1.4
1.3
ratio
—
6
30
451
3363
1.52
11.06
4.2
3.9
16.8
8.0
mg/mmol
2.89
320
2110
79
347
2.36
11.00
1.9
3.7
42.4
55.7
mg/l
0.34
61
283
953
10548
0.64
10.86
5.7
5.0
2.4
2.7
mmol/l
16.21
873
9674
51
182
2.88
10.79
1.5
1.7
—
—
—
0
0
430
3190
1.52
10.74
3.6
3.2
459.3
265.2
mg/l
0.41
311
2022
1076
11572
0.59
10.66
59.1
21.4
4.1
4.5
e12/l
72.83
1049
11248
62
247
2.59
10.63
3.1
3.2
0.9
0.9
nmol/l
0.01
51
193
62
247
2.59
10.63
5.1
1.8
—
—
—
0
0
1076
11570
0.59
10.60
58.9
21.3
30.7
30.4
pg
4.72
1059
11390
327
2290
1.57
10.58
1.9
1.7
577.1
26586047.8
pmol/l
1.88
279
1892
19
33
5.83
10.55
1.4
1.4
—
—
—
0
0
29
73
4.04
10.52
7.1
3.9
—
—
—
0
0
1077
11575
0.59
10.51
59.7
21.6
123.1
135.7
g/l
85.40
1058
11391
129
699
1.94
10.47
3.5
2.8
4.2
4.1
e9/l
0.18
99
533
1077
11570
0.60
10.36
58.9
21.3
92.4
91.2
fl
8.56
1059
11392
933
10349
0.65
10.32
5.5
4.5
4.3
4.6
mmol/l
16.61
861
9561
1077
11567
0.60
10.27
59.1
21.4
210.6
245.9
e9/l
37.01
1050
11273
1078
11575
0.60
10.27
59.1
21.4
7.0
6.8
e9/l
2.80
1052
11251
926
10284
0.65
10.25
5.4
4.4
1.3
1.4
mmol/l
12.31
849
9420
53
202
2.69
9.93
2.8
2.6
—
—
—
0
0
38
120
3.23
9.92
1.7
1.5
—
—
—
0
0
35
106
3.37
9.76
2.0
1.3
—
—
—
0
0
166
996
1.76
9.73
2.5
2.5
9.6
7.2
ug/l
0.69
141
872
318
2254
1.54
9.63
7.3
4.4
—
—
—
0
0
27
69
3.97
9.61
1.3
1.2
29.7
36.2
mmol/l
0.75
22
62
20
40
5.06
9.58
1.4
1.3
69.6
54.8
%
0.86
14
31
469
3606
1.47
9.58
4.6
3.3
2.3
2.4
mmol/l
9.97
407
3127
63
267
2.43
9.52
5.1
1.8
—
—
—
0
0
63
268
2.42
9.44
5.1
1.8
—
—
—
0
0
66
290
2.34
9.21
3.1
2.8
22.6
24.9
mmol/l
2.95
59
254
62
268
2.38
8.98
5.1
1.8
—
—
—
0
0
36
118
3.11
8.86
1.0
1.1
—
—
—
0
0
162
2518
0.59
8.83
2.6
3.0
0.7
0.8
ug/l
0.14
114
1654
37
124
3.04
8.78
1.4
1.4
—
—
—
0
0
571
4623
1.42
8.57
19.4
9.4
0.0
0.0
e9/l
0.41
487
3774
16
29
5.57
8.51
1.6
1.6
—
—
—
0
0
129
750
1.80
8.40
1.2
1.2
—
—
—
0
0
32
859
0.36
8.27
1.1
1.4
—
—
—
0
0
60
267
2.31
8.16
1.1
1.1
—
—
—
0
0
26
73
3.61
8.15
1.2
1.1
—
—
—
0
0
10
11
9.15
8.09
1.2
1.3
—
—
—
0
0
11
14
7.92
7.99
1.0
1.5
—
—
mmol/l
—
0
0
33
110
3.05
7.92
7.5
3.8
—
—
—
0
0
140
849
1.73
7.88
6.0
3.8
1.2
1.2
mmol/l
4.77
134
736
59
265
2.28
7.87
4.7
1.8
—
—
—
0
0
34
117
2.96
7.74
1.3
1.6
—
—
—
0
0
100
555
1.87
7.57
1.4
1.2
—
—
—
0
0
18
41
4.44
7.44
1.7
2.0
127.1
68.0
ug/l
0.78
18
41
14
26
5.43
7.26
1.6
1.8
—
—
—
0
0
34
122
2.83
7.20
1.4
1.1
—
—
—
0
0
51
226
2.31
7.04
1.3
1.6
0.9
0.8
nmol/l
0.28
43
191
83
444
1.93
7.03
8.2
4.8
—
—
—
0
0
906
9928
0.71
7.01
5.1
4.0
1.4
1.3
mmol/l
1.19
834
9041
874
7754
1.39
6.94
6.8
4.0
19.4
12.3
mm/h
21.85
827
7127
34
125
2.77
6.90
1.5
1.6
—
—
—
0
0
34
125
2.77
6.90
1.5
1.6
—
—
—
0
0
34
125
2.77
6.90
1.5
1.6
—
—
—
0
0
34
125
2.77
6.90
1.5
1.6
—
—
—
0
0
50
222
2.30
6.88
2.1
2.2
117.3
131.6
g/l
3.51
36
167
937
10188
0.71
6.65
5.6
4.7
6.3
6.0
mmol/l
6.85
858
9238
22
64
3.48
6.58
1.2
1.2
—
—
—
0
0
46
202
2.32
6.50
4.3
3.0
3.4
4.4
e9/l
2.46
46
202
18
569
0.31
6.50
1.3
1.4
—
—
—
0
0
47
209
2.30
6.46
4.6
3.3
56.2
57.9
%
0.47
47
209
44
191
2.35
6.39
2.9
2.2
308.0
3972.5
u/l
1.72
17
74
356
2764
1.40
6.38
1.7
1.4
—
—
—
0
0
32
119
2.73
6.37
1.3
1.3
—
—
—
0
0
16
38
4.25
6.29
1.1
1.0
—
—
—
0
0
12
23
5.26
6.01
1.5
1.2
29.6
25.3
%
—
7
17
21
63
3.37
6.01
1.4
1.4
1.3
1.1
nmol/l
0.51
16
49
399
3183
1.37
6.00
5.1
3.9
—
—
—
0
0
14
31
4.55
5.99
14.9
7.7
—
—
—
0
0
10
16
6.29
5.96
2.0
1.6
—
—
—
0
0
10
9
11.19
5.80
1.4
1.0
—
—
—
0
0
14
32
4.41
5.77
1.5
1.5
—
—
—
0
0
56
281
2.04
5.73
2.1
2.1
12.1
11.8
mg/l
0.10
51
254
10
17
5.92
5.63
3.1
1.3
—
—
—
0
0
14
33
4.28
5.56
1.1
2.2
—
—
—
0
0
12
25
4.84
5.50
1.8
1.1
—
—
—
0
0
8
5
16.09
5.41
1.1
1.0
—
—
—
0
0
27
103
2.66
5.17
1.1
1.2
—
—
—
0
0
24
86
2.82
5.16
1.8
2.1
0.9
1.2
e9/l
0.76
13
47
51
261
1.99
4.98
1.3
1.1
2.1
2.8
u/ml
—
7
20
59
319
1.89
4.92
1.6
2.8
33.9
37.5
g/l
3.38
48
273
18
56
3.25
4.90
5.9
3.1
3233.1
1495.3
u/ml
0.79
18
56
14
37
3.81
4.82
1.5
1.2
—
—
—
0
0
11
24
4.61
4.78
15.2
8.7
—
—
—
0
0
10
20
5.03
4.78
1.2
1.1
—
—
—
0
0
10
20
5.03
4.78
1.6
1.3
—
—
—
0
0
184
1339
1.44
4.67
1.3
1.3
—
—
—
0
0
353
4281
0.76
4.60
4.0
5.0
2.5
2.9
ug/l
0.29
314
3826
19
65
2.95
4.45
1.9
2.3
423.5
471.4
e6/l
0.16
13
57
47
244
1.96
4.44
1.4
1.3
299.6
198.3
miu/ml
—
10
111
158
1134
1.45
4.32
1.4
1.3
—
—
—
0
0
10
22
4.57
4.30
2.5
1.8
18.0
259.1
e6/l
—
5
11
18
63
2.88
4.07
1.9
2.3
0.2
0.2
e9/l
0.04
13
57
18
64
2.84
3.96
1.9
1.9
14.8
12.4
%
—
9
29
33
157
2.13
3.96
1.1
1.1
20.3
112.9
iu/ml
—
5
37
18
443
0.40
3.94
1.9
1.7
—
—
—
0
0
32
151
2.15
3.92
2.0
2.5
—
—
—
0
0
153
1112
1.43
3.91
2.8
2.2
223.4
131.5
ug/g
1.27
126
888
20
76
2.66
3.91
2.4
2.8
36.3
43.5
%
—
7
19
17
59
2.91
3.90
1.0
1.3
157.6
146.8
nmol/l
0.30
17
59
23
95
2.45
3.81
1.2
1.4
1.1
1.4
nmol/l
0.65
23
84
39
201
1.97
3.80
1.5
1.4
—
—
—
0
0
7
8
8.79
3.77
3.0
2.4
—
—
—
0
0
15
50
3.02
3.69
2.4
1.8
—
—
—
0
0
33
162
2.06
3.68
1.2
1.4
—
—
—
0
0
21
85
2.49
3.64
1.2
1.2
—
—
—
0
0
8
247
0.32
3.60
1.3
1.7
—
—
—
0
0
1062
11113
0.76
3.55
31.4
10.2
61.0
26.4
u/l
8.77
1044
10707
6
6
10.04
3.50
1.0
1.2
—
—
—
0
0
806
8700
0.81
3.43
52.7
18.9
332.2
332.6
g/l
0.54
796
8634
18
70
2.59
3.39
4.0
2.8
—
—
—
0
0
10
27
3.72
3.35
1.0
1.6
—
—
—
0
0
472
4101
1.24
3.30
2.5
2.1
—
—
—
0
0
28
135
2.10
3.29
1.4
1.2
—
—
—
0
0
8
15
5.36
3.19
9.9
9.8
9.9
6.1
mmol/l
—
8
15
124
902
1.41
3.18
5.5
3.3
—
—
—
0
0
19
79
2.43
3.14
3.9
1.6
9.5
10.8
%
0.67
19
79
70
455
1.57
3.12
1.2
1.2
—
—
—
0
0
35
188
1.89
3.08
1.8
1.3
94.5
44.3
u/l
0.58
27
159
41
232
1.79
3.07
1.4
1.4
3.0
47.9
e6/l
1.09
32
185
41
232
1.79
3.07
1.5
1.4
330.3
665.7
e6/l
0.30
34
190
1038
10851
0.78
3.01
37.7
13.9
—
—
—
0
0
83
570
1.49
2.90
2.6
3.4
4.1
4.5
pmol/l
1.53
65
506
21
96
2.21
2.84
2.5
2.1
—
—
—
0
0
20
90
2.24
2.81
1.0
1.4
—
35.3
—
0
6
13
48
2.73
2.72
1.2
1.1
1.1
1.1
ratio
—
7
14
32
176
1.84
2.65
3.8
3.0
—
—
—
0
0
28
148
1.91
2.62
1.3
1.2
4.2
6.8
u/ml
0.52
19
60
11
275
0.39
2.59
1.1
1.2
—
—
—
0
0
46
284
1.64
2.57
2.3
2.4
208.3
86.5
ug/min
0.73
26
168
27
142
1.92
2.57
2.4
2.7
—
—
—
0
0
5
7
7.17
2.55
1.0
1.0
—
—
—
0
0
5
7
7.17
2.55
1.0
1.3
—
—
—
0
0
81
1124
0.70
2.48
1.6
1.6
—
—
—
0
0
11
39
2.84
2.48
1.3
1.0
1717.9
1711.5
miu/ml
0.01
11
39
6
12
5.02
2.40
2.0
3.7
—
—
—
0
0
5
8
6.27
2.37
8.2
3.6
—
—
—
0
0
5
8
6.27
2.37
1.0
1.0
—
—
—
0
0
13
52
2.52
2.36
4.9
14.7
—
—
—
0
0
48
310
1.57
2.27
1.4
1.2
—
—
—
0
0
21
106
2.00
2.26
1.3
1.5
—
—
—
0
0
77
551
1.42
2.23
2.5
2.4
—
—
—
0
0
9
29
3.12
2.22
1.3
1.2
—
—
—
0
0
19
95
2.01
2.11
2.1
2.3
636.0
646.9
ml
0.04
11
61
21
109
1.94
2.11
1.4
1.2
—
—
—
0
0
929
9729
0.84
2.07
8.3
5.9
40.7
40.1
mmol/mol
1.02
869
8951
5
10
5.01
2.07
1.2
1.5
—
—
—
0
0
24
415
0.57
2.03
1.0
1.1
—
—
—
0
0
53
360
1.49
2.03
1.6
1.6
—
—
—
0
0
39
247
1.60
2.03
1.4
1.5
7.3
9.4
u/l
0.54
29
200
20
105
1.92
1.96
1.6
2.4
—
—
—
0
0
16
79
2.04
1.85
1.3
1.4
11.0
11.6
mmol/l
—
10
23
18
94
1.93
1.80
1.7
2.3
2.9
1.9
u/field
0.29
11
41
15
74
2.04
1.75
2.0
2.2
508.6
498.4
min
—
10
51
20
110
1.83
1.73
1.5
1.5
563.9
307.4
pmol/l
0.70
15
90
20
111
1.81
1.69
1.9
2.1
—
—
—
0
0
28
172
1.64
1.68
1.3
1.5
—
—
—
0
0
13
63
2.07
1.60
1.2
1.5
—
—
—
0
0
234
2027
1.19
1.59
3.6
3.1
2.5
2.4
mmol/l
2.56
191
1783
20
331
0.60
1.50
23.1
10.0
—
—
—
0
0
16
87
1.85
1.46
1.6
1.4
—
—
—
0
0
7
28
2.51
1.45
1.6
1.6
—
—
—
0
0
6
22
2.73
1.43
1.3
2.0
—
—
—
0
0
75
580
1.31
1.43
1.4
1.2
276.5
204.4
u/ml
0.33
70
532
17
289
0.58
1.42
1.4
1.1
—
—
—
0
0
5
17
2.95
1.36
1.0
1.0
—
—
—
0
0
14
75
1.88
1.34
3.5
1.1
—
—
—
0
0
13
231
0.56
1.29
1.8
2.2
—
—
—
0
0
547
5106
1.12
1.28
5.4
3.6
0.0
0.0
estimate
0.00
117
955
10
49
2.05
1.22
1.4
1.9
—
—
—
0
0
912
9441
0.89
1.21
5.2
4.6
2.1
2.1
mu/l
0.07
846
8564
108
895
1.23
1.20
5.0
3.8
—
—
—
0
0
6
26
2.31
1.18
1.0
1.1
—
—
—
0
0
6
26
2.31
1.18
1.0
1.1
—
—
—
0
0
6
26
2.31
1.18
1.0
1.1
—
—
—
0
0
12
65
1.85
1.13
1.2
3.0
—
—
—
0
0
11
58
1.90
1.12
25.4
21.3
1561.2
1574.2
nmol/l
0.02
11
58
14
81
1.74
1.09
1.2
1.0
—
—
—
0
0
22
144
1.54
1.09
4.0
2.5
4.1
4.1
mmol/l
0.19
22
144
22
144
1.54
1.09
4.0
2.5
105.6
105.5
mmol/l
0.01
22
144
717
7499
0.90
1.08
4.7
4.0
—
—
—
0
0
17
105
1.63
1.06
1.1
1.4
482060.0
107904.9
e6/l
—
9
75
38
280
1.37
1.05
6.2
5.0
—
—
—
0
0
9
47
1.92
1.02
1.1
1.2
6.1
6.5
mmol/l
—
9
47
262
2384
1.12
0.93
5.3
3.6
—
—
—
0
0
35
262
1.35
0.90
1.4
1.8
25875.0
17949.6
e6/l
0.29
27
194
249
2274
1.12
0.84
6.6
4.0
1.0
1.0
kg/l
0.32
51
319
18
121
1.49
0.83
3.9
2.6
—
—
—
0
0
301
2781
1.11
0.82
6.4
3.9
0.0
0.0
estimate
0.69
108
924
79
664
1.20
0.82
4.3
3.0
—
—
—
0
0
14
213
0.65
0.81
1.1
1.3
—
—
—
0
0
1068
10883
0.90
0.80
50.7
17.2
4.0
4.0
mmol/l
0.04
1044
10593
8
48
1.67
0.78
2.5
3.1
—
—
—
0
0
63
757
0.82
0.78
1.3
1.4
—
—
—
0
0
20
141
1.42
0.74
4.3
2.5
—
—
—
0
0
10
60
1.67
0.72
1.4
3.1
—
—
—
0
0
113
993
1.15
0.71
1.5
1.5
—
—
—
0
0
5
26
1.93
0.70
1.0
1.2
—
17.0
—
0
5
7
41
1.71
0.70
2.7
2.4
—
—
—
0
0
73
621
1.19
0.69
1.1
1.2
107.6
148.0
iu/ml
0.59
22
245
14
93
1.51
0.69
2.0
1.5
—
—
—
0
0
7
42
1.67
0.68
2.7
3.4
—
—
—
0
0
25
326
0.76
0.64
1.2
1.1
—
—
—
0
0
533
5102
1.08
0.64
7.2
4.9
0.0
0.0
estimate
0.50
119
960
539
5163
1.08
0.64
5.5
3.6
0.0
0.0
estimate
0.80
118
927
295
2761
1.09
0.63
4.9
3.3
—
—
—
0
0
10
63
1.59
0.62
1.1
1.2
—
—
—
0
0
16
113
1.42
0.61
1.3
1.6
—
—
—
0
0
26
200
1.31
0.61
1.4
1.6
—
—
—
0
0
56
473
1.19
0.60
2.5
2.8
—
—
—
0
0
1060
10424
1.09
0.59
42.1
14.6
24.2
25.5
mg/l
0.82
992
8283
1069
10853
0.92
0.58
50.7
17.0
138.2
139.7
mmol/l
42.04
1046
10578
6
37
1.62
0.55
2.2
3.0
—
—
—
0
0
9
64
1.41
0.51
1.1
1.0
—
—
—
0
0
840
8574
0.94
0.46
50.2
17.7
15.1
13.7
%
64.18
826
8384
14
103
1.36
0.45
1.3
1.2
—
—
—
0
0
12
86
1.40
0.44
2.8
2.3
613.3
640.5
e6/l
—
6
32
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.6
1.9
—
—
—
0
0
5
34
1.47
0.40
2.6
2.5
—
—
—
0
0
763
7790
0.95
0.39
4.4
3.8
14.8
14.9
pmol/l
0.16
698
7026
13
171
0.76
0.39
1.3
1.1
—
14.2
—
0
9
5
37
1.35
0.37
1.6
1.3
—
—
—
0
0
69
621
1.12
0.36
1.3
1.3
—
51.0
—
0
30
28
235
1.20
0.36
2.3
1.8
2.1
5.6
iu/l
—
8
78
72
651
1.11
0.35
1.5
1.6
—
—
—
0
0
84
767
1.10
0.35
1.5
1.4
—
—
—
0
0
71
643
1.11
0.34
1.1
1.2
—
—
—
0
0
6
47
1.28
0.32
1.0
1.1
279.8
223.6
iu/ml
—
6
47
930
9422
0.95
0.31
44.5
15.8
36.2
39.9
%
23.14
599
6605
7
52
1.35
0.31
1.3
1.2
7.1
6.4
ug/l
—
7
44
11
85
1.30
0.28
2.6
1.8
—
—
—
0
0
40
446
0.89
0.26
1.6
1.8
—
—
—
0
0
157
1644
0.95
0.23
1.3
1.2
6.1
12.4
u/ml
1.12
45
624
20
172
1.17
0.22
1.4
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
9
114
0.79
0.20
5.9
2.2
13.7
13.2
%
—
9
114
73
689
1.06
0.17
2.5
2.5
—
18.0
—
0
33
5
70
0.71
0.16
4.8
2.2
—
—
—
0
0
15
130
1.16
0.15
1.4
1.6
81.4
61.7
%
—
7
88
17
150
1.14
0.14
1.1
1.1
—
—
—
0
0
17
150
1.14
0.14
1.1
1.1
—
—
—
0
0
92
885
1.04
0.12
2.0
2.2
12.9
12.8
nmol/l
0.03
83
784
15
133
1.13
0.12
1.8
1.2
—
—
—
0
0
5
46
1.09
0.09
1.4
1.1
—
369.3
—
0
10
16
145
1.10
0.09
1.5
1.2
—
—
—
0
0
11
97
1.14
0.09
1.4
1.3
8.8
30.8
%
—
6
65
33
313
1.06
0.07
1.6
1.4
21.1
27.5
iu/l
0.68
26
270
173
1700
1.02
0.07
1.3
1.3
51.6
33.7
iu/ml
0.82
59
525
12
132
0.91
0.06
1.2
1.0
5.7
5.5
u/ml
—
7
63
286
2833
1.01
0.05
2.0
1.6
1.5
1.4
mmol/l
0.87
257
2353
12
129
0.93
0.03
1.2
1.0
2.0
2.0
u/ml
—
7
54
12
127
0.94
0.01
1.6
1.3
0.7
0.6
nmol/l
0.42
12
119
52
526
0.99
0.00
5.4
3.8
—
—
—
0
0
15
148
1.01
0.00
1.1
1.1
0.3
2.1
u/ml
—
8
59
23
235
0.98
0.00
4.2
3.8
32.1
25.7
mg/l
0.34
15
147
12
115
1.04
0.00
1.6
1.3
—
—
nmol/l
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
1.2
1.1
—
—
—
0
0
6
60
1.00
0.00
1.3
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
12
120
1.00
0.00
1.8
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
9.4
—
0
5
0
5
0.00
0.00
0.0
1.6
—
330.6
—
0
5
6
59
1.02
0.00
3.3
7.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint K11_HEPFAIL and mortality.

Females

Parameter HR [95% CI] p-value
K11_HEPFAIL 5.676 [4.64, 6.95] < 0.001
Birth year 0.999 [0.99, 1.01] 0.734

During the follow-up period (1.1.1998 — 31.12.2019), 1261 out of 2843 females with K11_HEPFAIL died.

Males

Parameter HR [95% CI] p-value
K11_HEPFAIL 8.309 [6.57, 10.51] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 1973 out of 3664 males with K11_HEPFAIL died.

Mortality risk

Mortality risk for people of age

years, who have K11_HEPFAIL.

N-year risk Females Males
1 0.605% 0.979%
5 3.398% 8.39%
10 9.095% 20.469%
15 16.851% 36.282%
20 27.438% 53.177%

Relationships between endpoints

↥

Index endpoint: K11_HEPFAIL – Hepatic failure, not elsewhere classified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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