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Neuroendocrine tumor and carcinoma of small intestine

C3_SMALL_INTESTINE_NEUROENDOCRINE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C17
  • Cancer registry: Morphology ICD-O-3 8240|824[2-4]|8246|8249
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

450

4. Check minimum number of events

None

450

5. Include endpoints

None

450

6. Filter based on genotype QC (FinnGen only)

450

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF8

Similar endpoints

List of similar endpoints to Neuroendocrine tumor and carcinoma of small intestine based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 450 217 233
Unadjusted period prevalence (%) 0.09 0.07 0.10
Median age at first event (years) 63.05 61.11 64.85

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
419
Matched controls
4188
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
2056.9
295.5
252
*
JFB00
NOMESCO Finland
Partial resection of small intestine
132.5
189.6
194
27
130
Kela drug reimbursment
Malignant tumour
26.5
162.0
248
217
8240/3-C17.9
ICD-O-3
Neuroendocrine tumor, NOS, of small intestine, NOS
+∞
153.9
138
*
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
422.9
148.9
141
5
H01CB03
ATC
lanreotide; parenteral
953.1
142.8
132
*
C17.2
ICD-10 Finland
Malignant neoplasm: Ileum
630.6
141.2
132
*
E34.0
ICD-10 Finland
Carcinoid syndrome
1711.0
132.8
122
*
H01CB02
ATC
octreotide; parenteral
851.0
131.0
122
*
8240/3-C17.2
ICD-O-3
Neuroendocrine tumor, NOS, of ileum
+∞
117.3
107
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
14.2
69.6
126
123
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
763.8
68.0
65
*
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
264.8
67.3
67
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
26.0
66.5
94
46
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
127.8
61.8
65
6
JN3BD
NOMESCO Finland
Extensive abdominal CT
7.9
61.0
161
305
JN4BD
NOMESCO Finland
Extensive body CT
7.7
60.3
163
319
8249/3-C17.9
ICD-O-3
Neuroendocrine tumor, grade 2 of small intestine, NOS
+∞
52.2
49
*
D77
ICPC
Malignant digestive neopl other/NOS
103.0
50.2
54
6
8249/3-C17.2
ICD-O-3
Neuroendocrine tumor, grade 2 of ileum
+∞
50.0
47
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
50.5
47.7
57
13
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
180.1
46.9
48
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
13.2
46.6
85
79
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
14.5
46.5
81
68
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
37.0
43.2
55
17
C17.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of small intestine
232.6
41.7
42
*
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
13.6
40.9
73
64
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
4.1
40.3
234
983
B01AB05
ATC
enoxaparin; parenteral
4.0
39.0
227
948
JN4CD
NOMESCO Finland
Very extensive body CT
10.6
38.9
79
90
JN4AD
NOMESCO Finland
Body CT examination
6.5
36.0
102
196
JFB30
NOMESCO Finland
Right hemicolectomy
18.3
35.8
56
35
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
6.6
34.0
95
178
302
Kela drug reimbursment
Interferon alfa
+∞
32.7
31
*
UJF32
NOMESCO Finland
Coloscopy
3.6
31.2
190
780
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.5
30.5
199
859
T73
ICPC
Neoplasm endocrine other/unspecified
+∞
29.5
28
*
JAH00
NOMESCO Finland
Laparotomy
13.3
29.4
52
44
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
15.8
29.2
48
34
C10AC01
ATC
colestyramine; oral
12.2
28.7
53
49
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
11.5
28.4
54
53
WX408
NOMESCO Finland
General anesthesy, balanced
3.4
28.3
182
764
JFB20
NOMESCO Finland
Ileocaecal resection
83.6
28.2
31
*
C17.1
ICD-10 Finland
Malignant neoplasm: Jejunum
300.4
28.1
28
*
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
20.5
27.6
41
22
JKA20
NOMESCO Finland
Cholecystectomy
10.5
26.6
53
57
TPH07
NOMESCO Finland
Cathetrisation of artery
4.7
26.6
101
266
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
37.0
24.6
31
9
L03AB05
ATC
interferon alfa-2b; parenteral
59.8
24.3
28
5
8246/3-C17.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of small intestine, NOS
+∞
23.1
22
*
C17.0
ICD-10 Finland
Malignant neoplasm: Duodenum
242.6
22.8
23
*
JN7AN
NOMESCO Finland
Somatostatin receptor isotope imaging
+∞
22.1
21
*
JN7SN
NOMESCO Finland
Somatostatin receptor SPECT
+∞
22.1
21
*
JN3AD
NOMESCO Finland
Abdominal CT examination
4.9
21.7
76
181
8240/3-C17.0
ICD-O-3
Neuroendocrine tumor, NOS, of duodenum
+∞
21.0
20
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
18.1
20.8
32
19
UJF30
NOMESCO Finland
Ileoscopy through colon
4.2
20.1
82
227
A09AA02
ATC
multienzymes (lipase, protease etc.)
11.8
20.1
37
34
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
14.4
18.5
31
23
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.5
18.1
55
111
JAH01
NOMESCO Finland
Laparoscopy
7.8
18.1
42
59
L01AX03
ATC
temozolomide; systemic
21.2
18.0
26
13
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
13.4
17.4
30
24
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
8.4
17.2
38
49
JF1BD
NOMESCO Finland
Very extensive small bowel CT
52.3
17.1
20
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.8
16.9
130
573
UJF92
NOMESCO Finland
Capsular endoscopy
10.7
16.7
32
32
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
6.3
16.4
44
76
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
15.9
89
318
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.4
15.7
178
973
8246/3-C17.2
ICD-O-3
Neuroendocrine carcinoma, NOS, of ileum
+∞
15.7
15
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
15.7
131
607
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
39.7
15.5
19
5
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.4
15.5
47
95
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
29.9
15.3
20
7
A79
ICPC
Malignancy NOS
11.0
14.9
28
27
B01AB10
ATC
tinzaparin; parenteral
3.9
14.3
61
174
K56.7
ICD-10 Finland
Ileus, unspecified
11.5
14.2
26
24
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
11.5
13.7
25
23
R4190
NOMESCO Finland
Nutritional therapy
6.5
13.5
35
58
XX9AD
NOMESCO Finland
Complementary CT
+∞
12.6
12
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.0
12.0
49
135
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
48.1
11.9
14
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
11.9
59
191
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.1
11.7
209
1356
Z51.88
ICD-10 Finland
Other specified medical care
8.0
11.3
25
33
JN4DD
NOMESCO Finland
Scout CT scan of torso
28.9
10.8
14
5
JFA73
NOMESCO Finland
Excision of lesion of small intestine
112.7
10.5
11
*
Z51.5
ICD-10 Finland
Palliative care
3.4
10.3
50
159
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
24.1
10.3
14
6
ZX114
NOMESCO Finland
Intramuscular
11.7
10.1
18
16
A02BC02
ATC
pantoprazole; systemic
2.0
10.0
293
2245
WX402
NOMESCO Finland
General anaesthesia
2.5
10.0
87
398
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
9.4
9.6
19
21
N02AA05
ATC
oxycodone; systemic
2.4
9.5
91
440
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
9.1
213
1482
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.1
8.9
49
169
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
51.1
8.7
10
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
8.6
77
358
K56.0
ICD-10 Finland
Paralytic ileus
11.9
8.6
15
13
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
28.1
8.5
11
*
R10.0
ICD-10 Finland
Acute abdomen
5.2
8.5
25
50
8240/3-C17.1
ICD-O-3
Neuroendocrine tumor, NOS, of jejunum
+∞
8.4
8
*
JN5SR
NOMESCO Finland
Very extensive PET-CT of receptors in upper body
+∞
8.4
8
*
1522B
ICD-9 Finland
Malignant neoplasm of small intestine, including duodenum, Ileum[NEOPLASMA MALIGNUM ILEI,ALIA DEFINITA SEU NUD]
+∞
8.4
8
*
N02BE01
ATC
paracetamol; systemic, rectal
2.4
8.2
372
3229
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.2
8.1
93
487
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
17.6
8.1
12
7
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
34.0
8.1
10
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.5
7.9
36
110
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
15.4
7.8
12
8
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
8.3
7.7
16
20
D75
ICPC
Malignant neoplasm colon/rectum
12.1
7.6
13
11
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
7.5
58
250
C17
ICD-10 Finland
Malignant neoplasm of small intestine
81.4
7.4
8
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
11.1
7.3
13
12
C17.3
ICD-10 Finland
Malignant neoplasm: Meckel diverticulum
+∞
7.3
7
*
E340, C179
ICD-10 Finland
NA
+∞
7.3
7
*
C18.09
ICD-10 Finland
Malignant tumor of caecum other or unspecified histology
16.1
7.3
11
7
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
7.2
94
517
6402
FHL
Small bowel resection
30.6
7.2
9
*
L01BC06
ATC
capecitabine; oral
3.7
7.2
30
86
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.7
7.2
30
86
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
7.1
78
397
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
7.7
7.0
15
20
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.5
6.8
51
217
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.4
6.8
31
96
C26.0
ICD-10 Finland
Malignant neoplasm: Intestinal tract, part unspecified
22.9
6.7
9
*
D99
ICPC
Disease digestive system other
12.5
6.6
11
9
C26.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of digestive system
70.9
6.4
7
*
C18.99
ICD-10 Finland
Malignant tumor in unspecified location in the colon other or unspecified histology
14.6
6.4
10
7
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
6.4
61
294
B03BA03
ATC
hydroxocobalamin; parenteral
3.0
6.4
36
128
A04AA02
ATC
granisetron; systemic, transdermal
3.0
6.3
36
129
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
7.2
6.3
14
20
JJA20
NOMESCO Finland
Open biopsy of liver
27.1
6.2
8
*
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.1
6.2
32
109
ZX112
NOMESCO Finland
Subcutaneous
4.7
6.0
19
42

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
344
17
855.80
307.65
9.3
2.2
344.7
69.5
nmol/l
8.38
344
17
189
347
8.67
108.84
1.6
1.4
—
—
—
0
0
173
461
5.47
64.04
3.2
4.3
3.4
37.3
ug/l
1.24
135
390
134
367
4.78
46.40
2.6
2.2
0.2
0.2
g/l
1.59
126
343
68
119
6.55
38.46
1.4
1.5
208.2
277.0
ug/g
2.27
56
72
333
1953
3.71
34.39
8.4
6.9
1.2
1.2
mmol/l
2.01
277
1663
307
1796
3.23
30.05
7.0
6.0
1.2
1.2
mmol/l
0.89
295
1625
342
2147
3.47
29.35
15.8
9.4
3.7
4.2
e9/l
4.68
319
1878
232
1180
2.99
28.85
5.8
4.1
7.4
7.4
ph
0.46
54
213
201
959
2.98
27.87
11.8
7.0
—
—
—
0
0
408
2944
5.13
26.78
19.3
7.9
88.7
80.0
u/l
1.76
402
2751
72
182
4.52
26.69
2.1
3.4
18.6
7096.6
u/ml
0.69
66
153
234
1238
2.85
26.38
3.0
2.3
—
—
—
0
0
135
545
3.11
24.78
2.9
2.4
21.0
22.0
%
0.28
116
464
29
6
51.46
24.58
2.0
2.3
50.7
102.5
pmol/l
—
23
6
237
1302
2.73
24.23
4.3
3.1
1351.1
1350.1
ng/l
0.00
212
1113
292
1790
2.80
23.87
4.6
4.0
—
—
—
0
0
118
459
3.13
22.91
2.8
2.8
9.8
10.0
umol/l
0.03
106
410
226
1238
2.66
22.87
9.4
5.6
—
—
—
0
0
142
618
2.90
22.51
3.0
2.4
12.2
12.7
umol/l
0.28
136
570
97
339
3.37
22.47
3.4
3.1
113.8
209.3
ng/l
3.32
88
308
183
935
2.61
20.93
2.6
2.3
—
—
—
0
0
25
28
9.39
20.49
1.1
1.2
—
—
—
0
0
336
2311
2.79
20.28
6.3
4.8
6.7
6.8
mmol/l
0.25
331
2177
230
1328
2.50
20.07
7.4
3.5
2.3
2.4
mmol/l
0.42
213
1151
270
1681
2.52
19.94
8.7
9.2
1.3
1.3
inr
0.14
87
447
216
1248
2.41
18.36
3.0
2.5
60.0
56.9
u/l
0.36
207
1158
268
1723
2.37
17.56
10.0
5.7
3.2
2.9
%
1.55
258
1602
261
1680
2.32
16.76
10.1
5.7
0.7
0.7
%
1.02
252
1567
278
1838
2.34
16.75
10.0
5.6
0.6
0.6
e9/l
0.78
249
1576
266
1734
2.31
16.47
10.3
6.0
9.6
8.8
%
3.82
257
1621
281
1875
2.33
16.45
10.0
5.7
1.6
1.9
e9/l
4.36
250
1653
278
1847
2.32
16.43
10.0
5.6
0.0
0.0
e9/l
1.29
247
1596
269
1766
2.30
16.31
10.2
5.9
26.5
27.0
%
0.31
260
1641
175
963
2.34
16.16
2.7
2.1
3.2
3.2
mg/l
0.14
157
833
281
1906
2.26
15.37
10.1
5.9
0.2
0.2
e9/l
0.10
251
1674
88
358
2.81
15.29
2.9
2.4
33.4
31.9
u/l
0.15
77
301
262
1740
2.21
14.94
10.2
5.6
57.8
57.6
%
0.10
252
1630
126
634
2.37
13.99
5.5
3.2
0.8
0.8
mmol/l
1.41
120
596
232
1507
2.11
13.54
2.7
2.2
—
—
—
0
0
246
1646
2.09
13.12
18.1
9.7
0.0
0.0
e9/l
0.54
216
1347
12
0
+∞
12.56
1.8
0.0
—
—
—
0
0
176
1058
2.09
12.34
3.6
3.1
—
—
—
0
0
139
782
2.12
11.46
3.3
2.9
582.5
555.4
mosm/kgh2o
0.73
118
670
137
772
2.11
11.22
5.7
3.1
2.5
2.5
mmol/l
0.07
129
677
178
1105
2.01
11.18
3.6
3.2
0.6
0.6
e6/l
0.07
141
835
224
1511
1.96
11.03
3.5
2.6
158.2
150.1
ug/l
0.18
211
1383
190
1213
1.98
10.97
3.8
3.3
48.9
110.7
e6/l
0.57
152
948
180
1128
1.99
10.96
5.7
4.3
—
—
—
0
0
142
831
2.04
10.38
2.7
2.6
5.2
4.6
e6/l
0.30
119
735
95
477
2.26
10.31
1.5
1.3
—
—
—
0
0
203
1379
1.86
9.31
4.4
3.8
395.3
97.0
e6/l
0.61
157
1012
115
648
2.04
9.19
3.3
2.9
2.9
2.0
e6/l
0.38
64
368
87
443
2.19
9.05
1.4
1.3
—
—
—
0
0
228
1620
1.83
8.93
2.3
2.0
85.4
95.7
pmol/l
2.91
151
828
68
320
2.33
8.51
4.8
4.0
1.2
1.2
mmol/l
0.38
68
277
19
42
4.68
8.19
1.2
1.2
0.6
0.5
nmol/l
0.70
19
37
97
538
2.02
8.00
1.6
1.2
—
—
—
0
0
67
328
2.23
7.62
6.6
8.3
—
—
—
0
0
412
3647
2.54
7.35
27.9
15.7
28.5
24.8
mg/l
1.62
383
2923
88
491
1.98
7.09
4.1
7.3
12.6
12.1
kpa
0.39
82
473
88
491
1.98
7.09
4.1
7.3
5.1
5.1
kpa
0.18
83
473
17
39
4.49
7.02
1.1
1.2
—
—
—
0
0
28
92
3.18
7.02
1.1
1.1
—
91.7
titre
—
0
6
331
2728
1.81
7.01
4.9
4.2
—
—
—
0
0
44
187
2.50
6.87
1.3
2.0
1.5
1.5
g/l
0.10
35
167
76
407
2.04
6.85
4.2
7.9
119.7
121.4
g/l
0.28
71
397
48
214
2.39
6.77
5.0
9.5
—
—
—
0
0
147
988
1.72
6.46
1.8
1.6
21.6
21.1
nmol/l
0.15
137
821
86
492
1.92
6.41
4.2
7.3
0.2
1.2
mmol/l
1.52
67
393
16
39
4.22
6.14
1.2
1.2
—
—
nmol/l
—
0
0
32
125
2.68
5.93
3.8
3.6
—
—
—
0
0
325
2732
1.68
5.67
4.7
3.8
14.3
14.9
pmol/l
4.62
303
2432
116
755
1.72
5.62
1.7
1.8
1272.2
1210.0
nmol/l
0.22
93
574
167
1196
1.63
5.61
3.7
3.3
—
—
—
0
0
16
42
3.91
5.58
1.3
1.4
16002.0
32982.8
e6/l
—
5
27
307
2559
1.63
5.38
4.4
4.4
—
—
—
0
0
82
490
1.82
5.30
2.5
2.5
1.7
1.8
%
0.20
75
451
68
385
1.90
5.19
2.1
2.2
223.6
138.0
ug/g
0.55
59
305
55
303
1.93
4.56
4.5
3.7
119.4
83.4
ng/l
1.60
50
265
14
39
3.67
4.52
1.2
1.4
—
—
—
0
0
15
45
3.41
4.36
1.3
1.4
15858.4
1150.4
e6/l
—
7
33
39
197
2.07
4.12
1.4
1.3
—
—
—
0
0
200
1579
1.48
4.00
3.7
3.9
59.2
35.2
ng/l
0.49
142
1206
20
78
2.64
3.77
5.4
4.4
4.8
2.2
mmol/l
2.05
15
51
9
16
5.72
3.67
3.2
1.5
23.8
29.3
umol/l
—
9
16
8
13
6.24
3.51
1.0
1.2
—
—
—
0
0
410
3814
1.84
3.44
27.2
14.7
—
—
—
0
0
87
596
1.57
3.33
2.2
2.0
—
—
—
0
0
19
78
2.50
3.26
2.7
3.8
—
—
—
0
0
9
19
4.81
3.25
5.7
4.8
—
—
—
0
0
12
38
3.22
3.23
1.6
1.4
—
—
—
0
0
7
12
5.90
3.03
1.0
1.1
—
—
—
0
0
13
46
2.88
2.94
3.2
3.1
—
—
—
0
0
123
930
1.44
2.91
1.4
1.3
—
—
—
0
0
49
301
1.70
2.89
4.5
4.1
—
—
—
0
0
113
848
1.44
2.78
2.0
1.8
98990298.1
427.3
pmol/l
0.50
99
696
59
387
1.60
2.71
5.5
3.6
—
—
—
0
0
9
24
3.80
2.68
1.2
1.2
—
—
—
0
0
57
373
1.60
2.65
5.6
3.5
1.2
2.0
mmol/l
0.59
46
301
80
567
1.50
2.62
26.5
24.7
1.2
1.3
inr
—
8
68
354
3238
1.44
2.55
32.6
16.9
37.6
39.5
%
3.87
274
2189
76
1032
0.68
2.39
1.7
1.6
1.4
1.4
mmol/l
0.24
61
840
12
46
2.65
2.37
1.3
1.5
—
—
—
0
0
55
369
1.56
2.32
2.5
2.6
66.0
70.7
e9/l
0.46
40
295
5
9
5.60
2.22
3.2
1.4
—
—
—
0
0
11
42
2.66
2.20
3.6
3.2
—
—
—
0
0
19
95
2.04
2.14
2.8
2.8
28.6
33.3
umol/l
0.55
14
78
213
1832
1.31
2.12
5.4
5.2
0.0
0.0
estimate
0.00
61
338
341
3647
0.73
2.07
4.2
4.7
1.4
1.5
mmol/l
0.92
309
3323
9
32
2.85
2.01
2.9
2.9
—
—
—
0
0
354
3760
0.73
2.00
4.5
5.3
2.5
2.7
mmol/l
2.69
319
3425
98
1234
0.74
1.93
2.9
3.2
—
—
—
0
0
12
52
2.34
1.89
1.2
1.8
—
—
—
0
0
330
3534
0.75
1.88
3.9
4.3
1.4
1.3
mmol/l
1.29
296
3205
8
28
2.89
1.87
2.3
1.9
—
—
—
0
0
345
3670
0.74
1.86
4.2
4.8
4.4
4.6
mmol/l
3.13
312
3373
213
1858
1.28
1.82
3.9
3.9
0.0
0.0
estimate
0.00
60
324
21
116
1.85
1.81
1.1
1.2
—
—
—
0
0
210
1833
1.27
1.77
3.9
3.9
0.0
0.0
estimate
0.00
61
338
28
171
1.68
1.75
4.5
3.9
—
—
—
0
0
9
36
2.53
1.75
1.1
1.1
—
—
—
0
0
41
278
1.52
1.69
4.8
6.5
24.0
24.6
mmol/l
0.49
35
262
34
221
1.58
1.68
1.1
1.2
—
—
—
0
0
13
62
2.13
1.67
2.2
3.0
4.3
4.5
e9/l
0.17
13
62
43
297
1.50
1.63
3.2
4.3
—
—
—
0
0
8
171
0.46
1.62
1.8
1.4
—
—
—
0
0
33
218
1.55
1.54
2.7
2.5
—
—
—
0
0
0
42
0.00
1.53
0.0
1.2
—
—
—
0
0
5
15
3.36
1.52
3.2
1.5
—
—
—
0
0
60
449
1.39
1.50
1.9
1.6
—
—
—
0
0
13
65
2.03
1.50
2.4
3.5
56.8
59.4
%
0.40
13
65
27
171
1.62
1.50
1.1
1.3
—
—
—
0
0
16
87
1.87
1.47
2.3
2.8
—
—
—
0
0
356
3352
1.30
1.45
5.6
4.6
2.0
2.3
mu/l
0.52
329
3012
6
136
0.43
1.42
1.2
1.1
—
—
—
0
0
13
67
1.97
1.39
2.9
3.3
15.8
26.2
u/ml
0.50
13
67
5
17
2.96
1.36
1.0
1.2
—
—
—
0
0
95
775
1.29
1.34
3.9
4.1
82.7
239.1
ng/l
1.55
80
639
19
305
0.61
1.33
1.5
1.4
—
—
—
0
0
0
40
0.00
1.33
0.0
2.7
—
654.3
—
0
24
48
356
1.39
1.29
1.5
1.5
—
—
—
0
0
45
332
1.39
1.25
1.5
1.5
—
—
—
0
0
299
2779
1.23
1.25
3.8
4.2
17.6
13.1
mm/h
3.40
280
2542
6
25
2.42
1.24
1.0
1.4
—
—
—
0
0
11
56
1.99
1.23
1.1
1.0
—
—
—
0
0
50
377
1.37
1.22
7.0
4.4
—
—
—
0
0
370
3523
1.28
1.22
7.6
6.3
40.8
40.5
mmol/mol
0.28
358
3258
8
38
2.12
1.19
1.5
1.3
282.3
287.2
pmol/l
—
8
30
15
87
1.75
1.16
1.2
1.2
—
—
—
0
0
5
20
2.52
1.15
2.4
2.0
—
—
—
0
0
12
65
1.87
1.14
1.1
1.4
—
—
—
0
0
14
80
1.77
1.14
2.5
2.5
14.1
16.3
%
—
8
39
17
104
1.66
1.11
1.5
1.9
—
—
—
0
0
20
128
1.59
1.10
3.5
6.9
1.5
1.2
mmol/l
0.60
13
112
5
21
2.40
1.09
2.0
2.0
—
—
—
0
0
7
32
2.21
1.08
1.1
1.3
—
—
—
0
0
44
573
0.74
1.08
1.3
1.3
1.2
14.4
u/ml
3.69
17
212
138
1206
1.21
1.05
4.0
4.1
—
—
—
0
0
13
75
1.76
1.04
2.2
2.5
—
—
—
0
0
44
336
1.34
1.02
3.2
3.4
64.7
66.7
g/l
0.93
39
306
0
30
0.00
0.97
0.0
2.8
—
502.8
—
0
20
115
996
1.21
0.96
4.1
3.5
—
—
—
0
0
0
32
0.00
0.95
0.0
1.0
—
243.9
—
0
19
118
1028
1.20
0.93
4.1
4.2
0.0
0.0
estimate
0.00
48
328
101
869
1.21
0.90
3.3
3.9
—
—
—
0
0
32
240
1.36
0.85
1.9
1.8
1.1
1.4
g/l
0.66
27
215
38
298
1.30
0.77
3.3
2.6
10.0
10.6
g/l
0.42
33
271
34
264
1.31
0.74
2.8
3.6
7.4
7.4
ph
—
7
29
7
38
1.86
0.74
1.0
1.1
—
—
—
0
0
79
679
1.20
0.73
1.6
1.5
2.5
2.6
g/l
0.27
51
399
5
25
2.01
0.73
1.6
4.2
—
—
—
0
0
7
40
1.76
0.71
1.1
1.4
—
—
—
0
0
36
284
1.29
0.70
4.3
4.5
0.5
1.1
%
0.21
11
86
9
59
1.54
0.68
1.0
1.1
—
—
—
0
0
5
27
1.86
0.68
1.6
4.1
—
—
—
0
0
73
840
0.84
0.65
4.0
4.3
1.0
1.0
kg/l
0.31
16
114
86
755
1.17
0.63
1.3
1.2
0.8
1.4
u/ml
1.22
23
201
8
52
1.55
0.59
2.3
2.0
91.4
90.5
%
—
8
52
14
194
0.71
0.56
1.3
1.3
—
—
—
0
0
6
38
1.59
0.54
1.2
1.1
—
—
—
0
0
9
134
0.66
0.52
1.8
1.4
—
—
—
0
0
37
307
1.22
0.51
4.4
4.4
0.2
0.1
%
0.06
12
103
136
1255
1.12
0.50
2.8
3.0
6.8
7.5
mmol/l
1.41
113
1025
35
291
1.22
0.48
4.6
4.2
1.0
0.3
%
0.75
11
81
112
1024
1.12
0.48
3.1
2.8
378.3
8380.7
umol/l
5.00
96
867
12
86
1.41
0.45
1.3
1.3
—
—
—
0
0
89
807
1.13
0.44
1.7
1.7
1.5
1.3
mg/l
0.44
71
643
5
31
1.62
0.43
1.4
1.2
—
—
—
0
0
14
183
0.76
0.41
5.7
2.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
2.3
—
0
15
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.6
—
67.5
—
0
11
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
86
783
1.12
0.40
4.9
4.9
—
—
—
0
0
17
133
1.29
0.39
1.6
1.6
—
—
—
0
0
131
1223
1.10
0.39
2.7
3.2
77.7
301.7
mg/l
1.24
89
786
5
37
1.36
0.37
1.0
1.2
—
—
—
0
0
25
208
1.21
0.36
1.3
1.2
143.8
143.2
iu/ml
—
5
76
6
43
1.40
0.35
2.2
2.7
—
—
—
0
0
20
242
0.82
0.33
2.8
2.6
3.5
4.1
e9/l
0.76
14
184
6
88
0.68
0.33
1.0
1.2
466.3
485.4
mg/l
—
6
82
6
46
1.31
0.33
1.5
1.3
—
—
—
0
0
25
212
1.19
0.31
4.6
3.9
—
—
—
0
0
10
76
1.32
0.28
1.4
1.5
—
—
—
0
0
42
468
0.89
0.28
1.4
1.3
537.1
472.1
titre
—
7
111
9
116
0.77
0.27
2.8
2.0
10.9
13.6
mg/l
—
9
108
9
119
0.75
0.27
8.3
10.5
—
—
—
0
0
13
160
0.81
0.26
1.1
1.1
—
6.2
—
0
5
37
330
1.13
0.26
4.4
4.2
1.0
1.0
%
0.03
12
115
9
74
1.22
0.25
1.3
1.2
—
—
—
0
0
17
142
1.20
0.25
4.5
3.2
0.5
0.2
g/l
0.53
12
51
45
408
1.11
0.24
1.7
1.6
—
—
—
0
0
12
97
1.24
0.23
1.0
1.1
—
—
—
0
0
161
1548
1.06
0.23
4.6
5.2
2.3
2.7
ug/l
0.56
141
1379
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
8
101
0.79
0.21
1.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
95
902
1.07
0.20
3.0
3.1
0.8
0.8
ug/l
0.03
68
622
371
3665
1.07
0.19
5.9
4.9
6.3
6.0
mmol/l
2.88
359
3318
6
52
1.16
0.19
1.0
1.2
—
—
—
0
0
23
204
1.13
0.18
2.6
2.4
0.7
0.7
%
0.02
23
198
19
215
0.88
0.17
1.3
1.4
—
—
—
0
0
8
70
1.15
0.16
2.5
2.8
—
—
—
0
0
25
226
1.11
0.15
4.8
2.8
0.2
0.3
e6/l
0.42
25
221
58
612
0.94
0.14
1.1
1.3
25.3
39.4
iu/ml
0.56
23
195
14
159
0.88
0.13
1.4
2.1
—
—
—
0
0
18
200
0.90
0.12
3.5
3.6
—
—
—
0
0
27
249
1.09
0.12
1.3
1.2
—
—
—
0
0
31
288
1.08
0.12
3.5
2.7
—
—
—
0
0
31
332
0.93
0.11
1.3
1.5
—
—
—
0
0
12
106
1.14
0.10
1.2
1.1
—
—
—
0
0
5
47
1.06
0.09
1.6
1.2
—
—
—
0
0
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
5
62
0.80
0.08
1.0
1.3
—
270.4
—
0
25
5
63
0.79
0.08
1.0
1.7
—
—
—
0
0
5
64
0.78
0.08
4.4
4.0
3.2
1.7
%
—
5
54
10
88
1.14
0.08
1.2
1.2
—
—
—
0
0
6
75
0.80
0.07
1.0
1.1
3.7
3.8
mmol/l
—
6
68
132
1299
1.02
0.06
3.5
3.9
22.3
7.5
mg/mmol
0.93
84
818
11
119
0.92
0.04
1.6
1.3
0.3
0.2
g/l
0.48
11
114
51
498
1.03
0.03
1.5
1.4
—
—
—
0
0
14
132
1.06
0.02
1.1
1.0
—
—
—
0
0
11
103
1.07
0.02
5.9
5.4
—
—
—
0
0
14
147
0.95
0.01
2.1
2.1
159.9
313.2
ug/l
1.06
14
137
24
233
1.03
0.01
1.2
1.4
—
—
—
0
0
121
1204
1.01
0.00
3.0
2.1
193.4
218.1
u/l
0.24
114
1128
10
102
0.98
0.00
2.0
1.7
—
—
—
0
0
26
263
0.99
0.00
4.6
3.0
—
—
—
0
0
35
347
1.01
0.00
2.9
3.5
—
—
—
0
0
37
367
1.01
0.00
1.7
1.6
—
—
—
0
0
12
121
0.99
0.00
8.3
4.7
—
—
—
0
0
0
9
0.00
0.00
0.0
8.2
—
—
—
0
0
5
51
0.98
0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
3.8
—
—
—
0
0
6
59
1.02
0.00
1.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
41.6
—
0
8
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
9
90
1.00
0.00
1.4
2.4
—
—
—
0
0
6
64
0.94
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
7
74
0.95
0.00
1.3
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
21.9
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
4.9
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_SMALL_INTESTINE_NEUROENDOCRINE – Neuroendocrine tumor and carcinoma of small intestine

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).