No definition available.
Sequelae of inflammatory diseases of the central nervous system
G6_NEUROINFSEQ
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
110 |
4. Check minimum number of eventsNone |
110 |
5. Include endpointsNone |
110 |
6. Filter based on genotype QC (FinnGen only) |
110 |
Control definitions (FinnGen only)
- Control exclude
- G6_NEUINFL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G00-G09
- Name in latin
- Sequelae morborum inflammatoriorum systematis nervosi centralis
Similar endpoints
↥List of similar endpoints to
Sequelae of inflammatory diseases of the central nervous system
based on the number of shared cases.
Similar with more cases:
- Inflammatory diseases of the central nervous system
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1421 | 653 | 746 |
| Only index persons | 880 | 437 | 443 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 43.55 | 45.47 | 41.45 |
| Only index persons | 36.06 | 39.65 | 32.52 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 110 | 56 | 54 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 38.41 | 32.54 | 44.49 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 97
- Matched controls
- 969
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G09
ICD-10 Finland
Sequelae of inflammatory diseases of central nervous system
+∞
59.7
51
*
32400
ICD-8 Finland
Late effects of intracranial abscess or pyogenic infection, Hydrocephalus acquisitus
+∞
20.5
19
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
14.1
14.0
24
22
A86
ICD-10 Finland
Unspecified viral encephalitis
+∞
10.6
10
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
30.6
8.7
11
*
N03AF01
ATC
carbamazepine; oral, rectal
8.2
8.6
19
28
XA800
NOMESCO Finland
Neuropsychological investigation
11.5
7.8
14
14
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
27.5
7.7
10
*
TAB00
NOMESCO Finland
Lumbar puncture
10.7
7.6
14
15
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
17.5
7.4
11
7
32401
ICD-8 Finland
Late effects of intracranial abscess or pyogenic infection, Status postencephaliticus
+∞
7.4
7
*
R51.80
ICD-10 Finland
Headache
4.4
6.7
25
71
N03AX14
ATC
levetiracetam; systemic
15.7
6.6
10
7
R4150
NOMESCO Finland
Neuropsychological rehabilitation
74.5
6.5
7
*
G06.0
ICD-10 Finland
Intracranial abscess and granuloma
+∞
6.3
6
*
2133
FHL
Suntin revisio
+∞
6.3
6
*
32408
ICD-8 Finland
Late effects of intracranial abscess or pyogenic infection, Alia definitae
+∞
6.3
6
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
8.2
6.2
13
18
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3044290) Cell count panel - Cerebral spinal fluid
11
18
6.68
6.56
3.3
1.1
—
—
—
0
0
(4027681)
9
7
13.84
5.69
1.3
1.1
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
9
8
12.11
5.39
1.2
1.0
—
—
—
0
0
(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid
11
23
5.20
5.13
3.9
1.1
e6/l
110.5
123.4
0.04
11
16
(3016543) Leukocytes [#/volume] in Cerebral spinal fluid
11
23
5.20
5.13
3.5
1.0
e6/l
454.7
2.9
0.48
11
16
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
9
9
10.76
5.13
1.2
1.0
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
8
7
12.19
4.86
1.3
1.0
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
8
10
8.52
4.13
1.5
1.0
—
—
—
0
0
(4062490)
7
8
9.24
3.83
1.1
1.0
—
—
—
0
0
(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy
6
5
12.58
3.81
1.3
1.0
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
29
146
2.34
3.46
1.7
1.7
nmol/l
1404.0
1204.9
0.67
24
112
(42870588) Differential panel, method unspecified - Blood
46
290
2.01
3.08
7.2
5.3
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
62
439
1.94
2.92
8.5
5.4
e9/l
0.0
0.0
0.04
54
393
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
5
6
8.65
2.77
1.0
1.2
—
—
—
0
0
(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay
5
6
8.65
2.77
1.4
1.0
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
19
87
2.43
2.77
3.5
8.0
mmol/l
1.0
1.1
0.03
12
74
(3032080) INR in Blood by Coagulation assay
51
343
1.91
2.76
6.7
7.8
inr
1.2
1.2
0.30
12
104
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
6
10
6.27
2.73
1.2
1.1
—
—
—
0
0
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
15
63
2.60
2.59
1.4
1.3
—
51.3
—
0
6
(3019198) Lymphocytes [#/volume] in Blood
62
451
1.86
2.58
8.7
5.4
e9/l
1.9
1.8
0.54
56
408
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
5
7
7.41
2.57
1.0
1.0
—
—
—
0
0
(40761535) Cells panel - Urine sediment
14
57
2.67
2.57
2.6
3.7
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
9
27
3.54
2.45
1.4
1.0
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
60
440
1.80
2.36
8.8
5.3
e9/l
0.6
0.6
0.76
52
393
(3023511) Choriogonadotropin [Units/volume] in Urine
7
18
4.08
2.29
1.9
1.3
—
—
—
0
0
(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma
27
155
1.98
2.27
2.3
2.7
mmol/l
2.5
2.5
0.45
21
136
(3013115) Eosinophils [#/volume] in Blood
61
457
1.75
2.17
11.0
5.8
e9/l
0.2
0.2
0.47
55
410
(3000330) Specific gravity of Urine by Test strip
10
37
2.87
2.17
9.1
3.7
—
—
—
0
0
(3036481) Cortisol [Moles/volume] in Serum or Plasma
17
83
2.24
2.15
2.8
1.7
nmol/l
276.2
388.1
2.65
17
75
(3037467) Urinalysis macro (dipstick) panel - Urine
75
599
1.79
2.11
7.1
4.0
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
21
115
2.02
2.00
1.4
2.0
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
37
245
1.77
1.99
4.9
3.0
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
20
108
2.04
1.98
2.2
1.5
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
20
108
2.04
1.98
1.8
1.5
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
71
566
1.72
1.93
5.7
4.1
—
52.0
—
0
14
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
18
95
2.07
1.89
8.2
6.8
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
66
520
1.67
1.84
13.6
9.9
e9/l
4.5
4.3
0.28
61
463
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
7
23
3.18
1.83
1.6
1.3
—
—
—
0
0
(3008037) Lactate [Moles/volume] in Venous blood
6
18
3.46
1.77
3.7
2.9
mmol/l
2.0
1.2
—
6
18
(3038515) Glucose [Moles/volume] in Venous blood
6
18
3.46
1.77
3.7
2.9
mmol/l
7.0
6.5
—
6
18
(3019832) Treponema pallidum Ab [Presence] in Serum
16
83
2.09
1.75
1.5
1.7
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
5
13
3.97
1.73
1.6
1.5
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
5
13
3.97
1.73
3.4
2.7
mmol/l
106.0
107.8
—
5
13
(3029634) Reagin Ab [Titer] in Serum by VDRL
5
13
3.97
1.73
2.2
1.4
—
—
—
0
0
(3033705) Calcium.ionized [Moles/volume] in Venous blood
5
13
3.97
1.73
3.4
2.7
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
5
13
3.97
1.73
3.4
2.7
mmol/l
4.2
3.8
—
5
13
(3023368) Bacteria identified in Blood by Culture
34
229
1.70
1.70
4.6
4.4
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
13
63
2.21
1.67
1.7
1.3
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
5
14
3.69
1.63
1.0
1.1
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
5
14
3.69
1.63
1.8
1.1
—
—
—
0
0
(3028707) Methadone [Presence] in Urine by Screen method
5
14
3.69
1.63
2.0
1.6
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
54
416
1.59
1.57
8.5
7.0
mmol/l
1.2
1.2
0.60
48
357
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
22
134
1.80
1.54
1.7
2.0
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
47
355
1.57
1.46
2.1
2.0
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
5
16
3.22
1.45
1.6
1.2
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
5
16
3.22
1.45
1.0
1.8
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
5
16
3.22
1.45
1.0
1.8
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
28
187
1.67
1.43
3.7
3.5
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
9
41
2.30
1.41
3.0
2.1
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
5
17
3.03
1.37
6.6
5.9
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
14
76
1.96
1.37
3.6
2.6
nmol/l
10.8
13.4
0.89
14
71
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
35
251
1.58
1.34
2.9
3.0
ng/l
808.0
1045.6
0.19
30
210
(3021589) Normoblasts [#/volume] in Blood
48
370
1.53
1.34
11.5
10.0
e9/l
0.0
0.0
0.50
39
306
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
9
43
2.19
1.34
1.6
1.8
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
11
55
2.11
1.32
4.2
3.6
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
8
34
2.46
1.32
2.4
2.5
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
8
37
2.25
1.24
1.6
1.4
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
8
37
2.25
1.24
1.6
1.4
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
8
37
2.25
1.24
1.6
1.4
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
8
37
2.25
1.24
1.8
1.8
nmol/l
39.6
33.4
—
8
37
(3035350) Ketones [Presence] in Urine by Test strip
53
423
1.49
1.23
5.0
3.5
estimate
0.0
0.0
—
10
86
(3021601) Nitrite [Presence] in Urine by Test strip
53
423
1.49
1.23
7.4
4.9
estimate
0.0
0.0
0.00
11
81
(1761868) Lipid panel - Serum or Plasma
23
329
0.62
1.21
3.1
2.9
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
8
38
2.19
1.21
1.5
2.3
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
8
38
2.19
1.21
1.6
1.4
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
20
128
1.69
1.19
2.6
2.6
e6/l
1.7
3.2
0.52
12
61
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
15
88
1.82
1.18
1.5
1.8
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
8
39
2.13
1.18
3.4
3.5
mmol/l
27.0
24.6
—
8
39
(3028026) IgM [Mass/volume] in Serum or Plasma
11
58
2.00
1.17
3.8
1.4
g/l
1.7
1.1
0.30
11
52
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
13
73
1.89
1.16
3.0
2.5
g/l
0.2
0.2
0.79
13
68
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
79
877
0.65
1.16
4.3
4.2
mmol/l
1.5
1.4
0.07
74
819
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
20
2.57
1.16
1.0
1.1
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
15
89
1.79
1.14
1.4
1.8
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
7
31
2.34
1.12
1.6
1.5
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
7
31
2.34
1.12
1.7
1.3
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
21
2.44
1.10
1.2
1.2
—
—
—
0
0
(3012544) pH of Venous blood
12
67
1.89
1.09
3.7
3.1
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
7
33
2.20
1.07
2.0
2.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
29
209
1.53
1.07
12.0
7.6
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
39
300
1.46
1.06
3.9
2.9
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
80
881
0.66
1.05
4.3
4.3
mmol/l
4.7
4.7
0.02
75
828
(3029937) Albumin [Presence] in Urine by Test strip
30
219
1.51
1.05
3.4
3.8
estimate
0.0
0.0
—
9
78
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
7
34
2.13
1.05
3.9
2.5
%
3.5
1.2
—
7
34
(3052851) Hemolysis interference index of Serum or Plasma
5
22
2.33
1.04
4.0
2.9
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
5
22
2.33
1.04
17.2
5.5
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
17
108
1.68
1.04
2.2
1.5
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
82
898
0.66
1.03
4.6
4.8
mmol/l
2.8
2.8
0.13
76
841
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
7
35
2.07
1.02
4.0
3.0
%
45.0
51.8
—
7
35
(3005322) IgE [Units/volume] in Serum or Plasma
9
49
1.91
1.01
1.0
1.2
u/ml
126.8
144.2
—
9
44
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
43
340
1.43
1.01
3.7
3.6
ng/l
27.9
49.9
0.70
36
229
(3016879) Cocaine [Presence] in Urine
7
36
2.01
0.99
1.7
1.4
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
52
429
1.40
0.95
5.0
3.6
estimate
0.0
0.0
—
9
79
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
77
847
0.70
0.90
3.9
3.9
mmol/l
1.4
1.3
0.24
71
790
(4035726)
13
80
1.71
0.89
1.4
1.3
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
41
328
1.40
0.88
5.3
3.6
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
6
31
1.99
0.86
2.8
1.1
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
35
275
1.40
0.83
2.9
2.3
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
20
141
1.51
0.82
2.6
2.4
e6/l
0.9
1.1
0.08
12
74
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
24
0.00
0.80
0.0
1.3
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
18
125
1.53
0.79
1.5
1.4
titre
464.0
402.2
—
5
37
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
0
27
0.00
0.78
0.0
1.4
—
191.9
—
0
15
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
6
34
1.81
0.77
1.8
2.1
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
6
109
0.52
0.77
1.0
1.3
—
—
—
0
0
(3019060) Gas panel - Arterial blood
9
55
1.69
0.76
3.9
4.1
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
5
24
2.13
0.75
1.0
1.3
—
—
—
0
0
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
5
24
2.13
0.75
1.2
1.3
—
—
—
0
0
(3044889) 12 lead EKG panel
55
629
0.75
0.75
3.3
3.7
—
—
—
0
0
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
5
25
2.05
0.73
1.8
4.8
g/l
0.0
0.0
—
5
25
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
7
40
1.80
0.73
1.6
1.7
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
37
300
1.35
0.72
3.1
2.7
u/l
29.4
31.3
0.20
37
283
(3020891) Body temperature
5
26
1.97
0.71
3.8
2.9
—
—
—
0
0
(3013512) EKG study
31
245
1.37
0.70
4.3
3.8
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
23
174
1.41
0.67
5.2
2.9
ng/l
21.1
111.3
1.12
18
131
(3022948) Iron [Moles/volume] in Serum or Plasma
19
139
1.44
0.66
2.7
2.3
umol/l
10.6
14.0
0.62
19
128
(3015377) Calcium [Moles/volume] in Serum or Plasma
37
305
1.32
0.64
2.7
3.4
mmol/l
2.4
2.4
0.08
32
267
(40761536) Microorganisms panel - Urine sediment
10
65
1.59
0.58
5.1
3.9
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
23
179
1.36
0.57
1.9
1.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
46
396
1.28
0.57
5.3
3.7
—
—
—
0
0
(3022621) pH of Urine by Test strip
9
61
1.52
0.55
2.6
2.2
—
—
—
0
0
(3000991) Gas panel - Venous blood
9
63
1.47
0.54
3.0
7.0
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
11
75
1.52
0.53
6.8
4.2
%
1.4
0.8
—
6
25
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
6
40
1.53
0.52
5.5
7.5
—
—
—
0
0
(3020630) Protein [Mass/volume] in Serum or Plasma
10
67
1.54
0.51
4.3
3.7
g/l
62.7
67.6
—
10
62
(40768797) Stomach Pathology biopsy report
17
128
1.39
0.51
1.1
1.2
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
6
95
0.61
0.44
2.0
1.5
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
77
819
0.80
0.44
6.1
5.4
mmol/mol
39.9
39.4
0.26
72
775
(3021440) Promyelocytes/100 leukocytes in Blood
10
70
1.47
0.43
7.3
4.3
%
0.1
0.2
—
5
22
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
5
32
1.59
0.43
1.6
1.4
—
—
—
0
0
(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
32
1.59
0.43
1.8
4.1
g/l
3.1
3.3
—
5
27
(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
33
1.54
0.42
1.8
4.0
g/l
3.5
3.6
—
5
27
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
5
33
1.54
0.42
8.2
1.9
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
5
33
1.54
0.42
1.8
4.0
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
17
133
1.33
0.41
2.0
1.5
—
—
—
0
0
(3023150) Myeloperoxidase Ab [Units/volume] in Serum
0
19
0.00
0.39
0.0
2.6
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
16
126
1.32
0.38
1.4
1.8
%
1.4
1.5
0.08
16
108
(3019150) Specific gravity of Urine by Refractometry
23
191
1.26
0.37
4.6
3.7
kg/l
1.0
1.0
—
5
22
(36304419) Bacteria [Presence] in Urine
28
240
1.22
0.35
3.9
2.8
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
23
193
1.24
0.34
2.6
1.3
g/l
2.3
2.5
0.31
18
122
(3004789) Transferrin [Mass/volume] in Serum or Plasma
16
128
1.29
0.34
2.8
2.3
g/l
2.3
2.4
0.22
16
112
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
37
327
1.20
0.34
2.0
2.0
pmol/l
93.6
98.6
0.28
19
163
(3003458) Phosphate [Moles/volume] in Serum or Plasma
13
101
1.33
0.33
11.9
5.7
mmol/l
0.9
1.0
0.51
13
95
(3030467) Casts [#/volume] in Urine by Automated count
28
242
1.21
0.32
4.4
2.8
e6/l
0.1
0.3
0.93
22
170
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
7
51
1.40
0.32
1.4
1.3
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
93
895
1.25
0.31
25.5
13.5
mg/l
19.9
22.3
0.38
82
714
(3018418) pH of Serum or Plasma
30
262
1.20
0.31
7.5
3.9
ph
7.4
7.4
—
6
51
(40760892) CBC W Ordered Manual Differential panel - Blood
24
208
1.20
0.27
8.8
4.6
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
30
266
1.18
0.26
4.2
2.9
e6/l
219.4
272.8
0.06
23
193
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
6
83
0.71
0.25
1.7
1.9
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
23
200
1.19
0.25
3.3
2.2
—
—
—
0
0
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
5
37
1.37
0.24
1.8
1.7
g/l
1.3
1.6
—
5
31
(40768443) Skin Pathology biopsy report
5
40
1.26
0.23
1.0
1.2
—
—
—
0
0
(3022145) Colonoscopy Study observation
8
103
0.76
0.22
1.0
1.3
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
5
42
1.20
0.22
5.8
6.3
mmol/l
24.7
24.8
—
5
42
(1617658) Protocol used for examination of sentinel lymph nodes
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3003434) Protein [Mass/volume] in Pleural fluid
0
11
0.00
0.21
0.0
1.5
—
28.2
—
0
11
(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay
0
11
0.00
0.21
0.0
1.2
—
4.6
—
0
5
(3022806) Fractional oxyhemoglobin in Capillary blood
0
10
0.00
0.21
0.0
2.6
—
86.2
—
0
10
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
10
0.00
0.21
0.0
1.3
—
203.1
—
0
10
(44790048)
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3036782) Glucose [Moles/volume] in Pleural fluid
0
12
0.00
0.21
0.0
1.2
—
6.4
—
0
12
(44790047)
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(44806118)
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(44790049)
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
13
0.00
0.21
0.0
2.8
—
89.2
—
0
13
(4268621)
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
3.4
—
3.3
—
0
13
(3013139) Helicobacter pylori Ag [Presence] in Stool
6
49
1.24
0.20
1.2
1.2
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
1.8
—
2.3
—
0
14
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
(3008898) HLA-B27 [Presence]
6
50
1.21
0.20
1.0
1.2
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
21
237
0.86
0.20
4.2
3.7
mg/mmol
8.1
11.1
0.15
13
148
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
20
176
1.17
0.19
1.4
1.3
iu/ml
13.6
33.0
—
7
60
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
57
600
0.90
0.18
2.9
3.1
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
7
58
1.22
0.18
1.6
1.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
21
235
0.87
0.18
1.4
1.4
—
—
—
0
0
(3002256) Pathology report gross observation
13
111
1.19
0.16
1.5
1.2
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
86
836
1.13
0.16
17.1
12.9
ml/min/173m2
84.3
83.0
0.20
77
684
(3000492) Spirometry study
12
102
1.20
0.16
1.3
1.3
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
10
117
0.84
0.13
2.2
2.0
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
26
239
1.12
0.13
5.7
3.3
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
9
105
0.84
0.13
1.9
1.9
—
—
—
0
0
(3019225) pH of Specimen
10
85
1.19
0.13
5.7
4.4
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
20
219
0.89
0.12
3.4
4.1
%
17.0
22.9
—
7
92
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
12
136
0.87
0.11
2.0
1.4
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
15
166
0.89
0.10
2.2
1.5
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
14
155
0.89
0.10
2.5
2.7
ug/l
0.4
0.8
—
9
91
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
6
55
1.10
0.09
6.3
2.8
mmol/l
2.4
1.1
—
6
41
(3025941) Bacteria identified in Stool by Culture
6
58
1.04
0.08
1.3
1.2
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
7
65
1.08
0.08
3.7
1.8
ng/l
465.7
119.0
—
7
56
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
8
73
1.10
0.08
5.1
3.4
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
80
814
0.94
0.07
24.4
14.2
%
39.7
40.7
0.36
54
625
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
15
161
0.92
0.05
1.5
1.3
u/ml
1.2
8.7
—
6
59
(40761511) CBC panel - Blood by Automated count
94
930
1.07
0.04
19.6
12.4
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
21
219
0.95
0.03
2.9
3.0
mg/l
34.2
372.5
0.59
15
137
(3026493) Urate [Moles/volume] in Serum or Plasma
23
239
0.95
0.03
3.0
2.7
umol/l
19868.8
2993.0
0.40
18
209
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
28
286
0.97
0.00
4.3
4.3
ug/l
1.2
2.0
1.37
28
263
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
82
815
1.02
0.00
5.4
4.7
mu/l
1.8
1.9
0.17
76
753
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
20
205
0.97
0.00
1.5
1.2
u/ml
3.1
1.1
—
6
59
(3002385) Erythrocyte distribution width [Ratio]
74
736
1.02
0.00
26.3
17.0
%
13.8
13.7
0.30
74
725
(3018095) Leukocytes [#/volume] in Urine
31
314
0.98
0.00
5.0
3.3
e6/l
277.3
41.4
0.63
24
207
(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013637) Mi-2 Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4146454)
0
6
0.00
0.00
0.0
3.5
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
5.3
—
—
—
0
0
(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035880) pH of Pleural fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3012441) Differential panel - Pleural fluid
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4281824)
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
6
0.00
0.00
0.0
12.7
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
6
60
1.00
0.00
6.7
2.7
kpa
5.0
4.9
—
6
53
(40768441) Liver Pathology biopsy report
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(4211845)
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
5.3
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(42529582) MDA5 Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017569) Oxygen content in Arterial blood
0
6
0.00
0.00
0.0
13.0
—
—
—
0
0
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
13.0
—
0
6
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
(40768806) Pleura Pathology biopsy report
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
7
0.00
0.00
0.0
1.4
—
13.0
—
0
7
(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005011) Chlamydia sp Ab [Titer] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4010399)
6
62
0.97
0.00
1.0
1.4
—
—
—
0
0
(3045788) Cell count panel - Pleural fluid
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
7
77
0.90
0.00
1.1
1.1
—
—
—
0
0
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid
0
7
0.00
0.00
0.0
1.3
—
8.4
—
0
7
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.4
—
1.0
—
0
9
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_NEUROINFSEQ and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_NEUROINFSEQ | 2.449 [1.58, 3.79] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.263 |
During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 211 females with G6_NEUROINFSEQ died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have G6_NEUROINFSEQ.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.273% | No data |
| 5 | 1.534% | No data |
| 10 | 3.802% | No data |
| 15 | 6.743% | No data |
| 20 | 11.591% | No data |
Relationships between endpoints
↥Index endpoint: G6_NEUROINFSEQ – Sequelae of inflammatory diseases of the central nervous system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data