Conductive hearing loss, unspecified

H8_HL_CON_NAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H90.0, H90.1, H90.2
  • Hospital discharge: ICD-9 3890
  • Cause of death: ICD-10 H90.0, H90.1, H90.2
  • Cause of death: ICD-9 3890

2 out of 7 registries used, show all original rules.

3426

4. Check minimum number of events

None

3426

5. Include endpoints

None

3426

6. Filter based on genotype QC (FinnGen only)

3426

Control definitions (FinnGen only)

Control exclude
H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 29372 15605 13612
Only index persons 27163 14637 12526
Unadjusted period prevalence (%)
Whole population 0.41 0.45 0.38
Only index persons 0.51 0.54 0.48
Median age at first event (years)
Whole population 47.02 48.69 45.13
Only index persons 47.49 49.19 45.51

-FinnGen-

Key figures

All Female Male
Number of individuals 3426 1986 1440
Unadjusted period prevalence (%) 0.66 0.68 0.63
Median age at first event (years) 53.03 50.98 55.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3083
Matched controls
30827
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
44.6
323.0
474
125
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
1209.6
323.0
419
*
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
1500.5
323.0
866
8
Z01.1
ICD-10 Finland
Examination of ears and hearing
17.9
323.0
1273
1162
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
148.5
323.0
1108
116
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
97.9
323.0
363
42
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
265.5
323.0
353
15
UDC00
NOMESCO Finland
Ear microscopy
15.2
323.0
745
632
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
+∞
323.0
336
*
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
9443.9
323.0
2076
8
DFF00
NOMESCO Finland
Pure tone audiometry
35.6
323.0
996
408
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
118.1
313.5
337
32
H80.9
ICD-10 Finland
Otosclerosis, unspecified
81.9
312.0
350
48
DDA00
NOMESCO Finland
Stapedotomy
115.5
297.8
321
31
DFF15
NOMESCO Finland
Speech audiometry
40.4
294.6
374
105
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
526.2
293.7
288
6
Z97.4
ICD-10 Finland
Presence of external hearing-aid
50.0
269.1
327
73
DC1AD
NOMESCO Finland
Temporalbone CT
61.7
239.9
281
50
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
36.4
217.1
282
85
DAX08
NOMESCO Finland
Fitting of hearing aid
54.3
208.8
250
50
H71
ICD-10 Finland
Cholesteatoma of middle ear
47.9
188.6
231
52
R5120
NOMESCO Finland
Preparation of an aid
29.5
181.4
248
91
H91.9
ICD-10 Finland
Hearing loss, unspecified
18.1
166.7
266
160
H02
ICPC
Hearing complaint
5.6
157.8
507
1048
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
124.4
153.8
165
14
H93.1
ICD-10 Finland
Tinnitus
12.2
152.3
288
259
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
43.2
149.7
187
46
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
17.4
139.2
225
139
DCD10
NOMESCO Finland
Tympanoplasty
153.1
138.6
146
10
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.1
126.6
560
1588
H65.3
ICD-10 Finland
Chronic mucoid otitis media
11.0
122.2
242
237
ZXC10
NOMESCO Finland
Use of laser
11.1
116.6
230
223
N07CA01
ATC
betahistine; oral
5.7
114.6
353
680
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
9.1
104.7
230
271
H91.1
ICD-10 Finland
Presbycusis
10.7
90.3
180
177
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
12.0
85.6
161
141
H80.1
ICD-10 Finland
Otosclerosis involving oval window, obliterative
106.5
85.4
93
9
SPAT1043
SPAT
Audiometry
4.1
83.6
354
942
TDA90
NOMESCO Finland
Removal wax from ear
18.1
77.3
122
70
R5140
NOMESCO Finland
Monitoring the use of the aid
3.3
75.5
423
1412
R4135
NOMESCO Finland
Rehabilitation for hearing problems
62.4
72.9
85
14
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
101.3
72.2
79
8
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
114.3
72.2
78
7
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.7
69.3
329
962
H74.1
ICD-10 Finland
Adhesive middle ear disease
45.4
68.3
84
19
3890A
ICD-9 Finland
Deafness, Conductive deafness
+∞
65.9
63
*
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
25.6
65.3
92
37
DCD00
NOMESCO Finland
Myringoplasty
23.5
60.4
87
38
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
64.1
59.6
69
11
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
21.6
56.8
84
40
DDD05
NOMESCO Finland
Plastic repair of ossicular chain
+∞
56.4
54
*
H65.2
ICD-10 Finland
Chronic serous otitis media
9.8
55.7
115
121
H60.9
ICD-10 Finland
Otitis externa, unspecified
3.5
54.0
274
840
H80.8
ICD-10 Finland
Other otosclerosis
139.9
52.0
55
*
H29
ICPC
Ear symptom/complaint other
2.9
50.5
343
1289
H66.9
ICD-10 Finland
Otitis media, unspecified
3.5
50.2
254
776
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
134.7
49.9
53
*
H60.3
ICD-10 Finland
Other infective otitis externa
6.8
47.1
122
185
DCA30
NOMESCO Finland
Exploration of middle ear
165.9
47.0
49
*
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
15.4
46.8
78
52
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
13.9
45.6
79
58
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
5.0
45.4
151
312
H81.0
ICD-10 Finland
Ménière disease
7.5
44.2
107
147
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
30.0
44.0
59
20
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
33.5
42.9
56
17
DFE00
NOMESCO Finland
Insertion of cochlear implant
+∞
42.8
41
*
DDB00
NOMESCO Finland
Stapedectomy
79.6
42.0
47
6
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
40.3
255
909
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
74.5
39.0
44
6
H80
ICD-10 Finland
Otosclerosis
138.4
38.8
41
*
H92.0
ICD-10 Finland
Otalgia
3.6
38.5
181
520
R42
ICD-10 Finland
Dizziness and giddiness
2.0
37.9
607
3441
H70.1
ICD-10 Finland
Chronic mastoiditis
26.4
37.6
52
20
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
8.4
37.6
84
102
DEA10
NOMESCO Finland
Attico-antrotomy
39.8
37.5
47
12
H60.8
ICD-10 Finland
Other otitis externa
4.9
36.3
124
264
H61.2
ICD-10 Finland
Impacted cerumen
3.1
35.6
204
681
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
13.1
35.6
63
49
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
32.6
34.4
45
14
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
34.3
838
5455
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
25.1
33.6
47
19
S02CA02
ATC
flumetasone and antiinfectives; otic
2.9
32.6
207
740
H91.8
ICD-10 Finland
Other specified hearing loss
15.8
32.5
53
34
ZXA00
NOMESCO Finland
Right side
1.7
32.3
789
5116
H13
ICPC
Plugged feeling ear
1.9
31.3
493
2758
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
21.2
31.3
46
22
RK520
NOMESCO Finland
NA
29.6
30.7
41
14
ZXA05
NOMESCO Finland
Left side
1.7
30.5
727
4668
H65.0
ICD-10 Finland
Acute serous otitis media
5.9
30.5
87
151
DGW00
NOMESCO Finland
Dilatation of eustachian tube
52.0
30.3
36
7
H01
ICPC
Ear pain/earache
2.2
30.3
331
1591
J01CA04
ATC
amoxicillin; systemic
1.7
30.1
2398
20945
4122
FHL
Tympanostomy (tympanic tube)
5.8
30.0
87
154
38699
ICD-8 Finland
NA
20.3
29.6
44
22
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
6.3
29.1
79
129
3870A
ICD-9 Finland
Otosclerosis involving oval window, nonobliterative
23.1
28.7
41
18
R01AD09
ATC
mometasone; nasal
1.6
28.6
1260
9488
4133
FHL
Stapedectomy sampling
29.6
28.5
38
13
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
28.2
27
*
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
9.5
27.6
57
61
DEB30
NOMESCO Finland
Radical mastoidectomy
47.6
27.4
33
7
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
+∞
27.1
26
*
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
21.9
26.9
39
18
RK320
NOMESCO Finland
NA
10.0
26.4
53
54
H91
ICD-10 Finland
Other hearing loss
13.3
26.4
46
35
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
26.3
1453
11445
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
25.9
492
2923
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
15.7
25.9
42
27
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
27.2
25.8
35
13
H74.3
ICD-10 Finland
Other acquired abnormalities of ear ossicles
94.2
25.7
28
*
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
16.0
25.4
41
26
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
7.3
25.2
61
85
DFX00
NOMESCO Finland
Connecting cochlear implant
+∞
25.0
24
*
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
23.6
24.8
35
15
H81
ICPC
Excessive ear wax
1.9
24.2
411
2348
H04
ICPC
Ear discharge
3.6
24.1
110
310
DCB10
NOMESCO Finland
Freeing of adhesions of middle ear
+∞
24.0
23
*
Q16.1
ICD-10 Finland
Congenital absence, atresia and stricture of auditory canal (external)
241.7
23.7
24
*
WX110
NOMESCO Finland
Local anesthesy
1.5
22.8
1946
16571
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
40.4
22.7
28
7
DDD10
NOMESCO Finland
Interposition between malleus and stapes
231.6
22.6
23
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
20.8
22.5
33
16
YPA00
NOMESCO Finland
Excision of blood vessel for transplantation
115.8
21.6
23
*
ZXA10
NOMESCO Finland
Bilateral
1.7
21.6
515
3270
R01AD08
ATC
fluticasone; nasal
1.5
21.1
766
5422
N02BE01
ATC
paracetamol; systemic, rectal
1.5
20.9
2441
21970
RK110
NOMESCO Finland
NA
8.3
20.9
46
56
DDA10
NOMESCO Finland
Exploration of ossicular chain
+∞
20.9
20
*
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
14.9
20.7
34
23
J01DB01
ATC
cefalexin; oral
1.5
20.3
2348
20989
H84
ICPC
Presbyacusis
4.6
20.0
70
155
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
19.9
193
873
H90
ICD-10 Finland
Conductive and sensorineural hearing loss
36.0
19.8
25
7
H73.1
ICD-10 Finland
Chronic myringitis
46.3
19.2
23
5
H81.3
ICD-10 Finland
Other peripheral vertigo
3.5
19.2
89
256
DDD20
NOMESCO Finland
Interposition between eardrum and footplate of stapes
+∞
18.8
18
*
4141
FHL
Myringoplasty (also for reasons other than inflammation)
12.4
18.1
32
26
Q17.2
ICD-10 Finland
Microtia
52.8
17.9
21
*
H28
ICPC
Limited function/disability (H)
8.7
17.9
38
44
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.8
17.7
75
200
Q16.3
ICD-10 Finland
Congenital malformation of ear ossicles
+∞
17.7
17
*
RK420
NOMESCO Finland
NA
67.0
17.7
20
*
R51.80
ICD-10 Finland
Headache
1.7
17.7
396
2457
AA1AD
NOMESCO Finland
CT of head and brain
1.6
17.7
576
3946
1450
FHL
Otomicroscopy
9.8
17.6
35
36
RK120
NOMESCO Finland
NA
21.0
17.3
25
12
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
8.9
17.1
36
41
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
17.1
554
3787
H61.8
ICD-10 Finland
Other specified disorders of external ear
5.6
16.9
49
89
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
+∞
16.7
16
*
H60
ICD-10 Finland
Otitis externa
2.5
16.6
132
541
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
3.2
16.2
84
264
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
16.8
16.1
25
15
DE2CM
NOMESCO Finland
Acoustic channel extensive MRI examination with 3 Tesla magnet
47.7
16.0
19
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
15.7
728
5377
WX002
NOMESCO Finland
Sedation and analgesia
1.6
15.5
510
3492
4151
FHL
Reoperation for chronic otitis media
160.7
15.5
16
*
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.7
15.3
51
109
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.9
15.2
214
1138
J01MA02
ATC
ciprofloxacin; systemic
1.4
15.1
971
7622
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
15.0
1936
17041
J01DA01
ATC
[U] cefalexin; systemic
1.4
15.0
1691
14567
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
14.9
599
4287
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
14.9
923
7190
UDC10
NOMESCO Finland
Tympanoscopy
56.9
14.8
17
*
H02AB06
ATC
prednisolone; systemic
1.4
14.7
1207
9864
H80.20
ICD-10 Finland
Otosclerosis involving round window
+∞
14.6
14
*
DEB00
NOMESCO Finland
Cortical mastoidectomy
80.5
14.6
16
*
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.9
14.6
233
1296
4161
FHL
Exploratory tympanotomy
150.7
14.5
15
*
DFF59
NOMESCO Finland
Other assessment of balance
6.1
13.9
37
61
S02.11
ICD-10 Finland
Fracture of base of skull, open
15.8
13.9
22
14
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
12.7
13.9
24
19
H83.1
ICD-10 Finland
Labyrinthine fistula
30.2
13.9
18
6
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
53.6
13.8
16
*
DDW99
NOMESCO Finland
Other operation on ossicles of ear
53.6
13.8
16
*
Q78.00
ICD-10 Finland
Congenital osteogenesis imperfecta
75.5
13.6
15
*
H74.0
ICD-10 Finland
Tympanosclerosis
75.5
13.6
15
*
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
6.6
13.5
34
52
DFF16
NOMESCO Finland
Speech-in-noise audiometry
140.6
13.5
14
*
H66
ICD-10 Finland
Suppurative and unspecified otitis media
2.9
13.2
79
277
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
40.2
13.1
16
*
R06.0
ICD-10 Finland
Dyspnoea
1.5
13.1
595
4357
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
13.1
202
1112
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
13.0
433
2963
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
12.7
417
2845
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
12.7
1027
8324
J01FA10
ATC
azithromycin; systemic
1.3
12.7
1567
13534
A02BC05
ATC
esomeprazole; systemic
1.3
12.4
1019
8271
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
11.7
12.3
22
19
M79.6
ICD-10 Finland
Pain in limb
1.4
12.3
892
7096
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
12.1
1120
9245
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
12.1
764
5935
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
21.4
12.0
17
8
J01AA02
ATC
doxycycline; systemic
1.3
12.0
2103
19035
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
11.9
705
5408
A98
ICPC
Health maint/preventive medicine
1.6
11.9
2850
27243
A02BC03
ATC
lansoprazole; oral
1.4
11.9
713
5487
A02BC02
ATC
pantoprazole; systemic
1.3
11.6
1678
14731
R5599
NOMESCO Finland
Other rehabilitation service
2.7
11.5
76
283
R01AD12
ATC
fluticasone furoate; nasal
1.4
11.5
735
5714
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
+∞
11.5
11
*
3891A
ICD-9 Finland
Deafness, Sensorineural deafness
+∞
11.5
11
*
EMB30
NOMESCO Finland
Adenotomy
2.5
11.5
85
340
Z71.8
ICD-10 Finland
Other specified counselling
1.4
11.3
599
4502
RK290
NOMESCO Finland
NA
11.8
11.3
20
17
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
35.1
11.3
14
*
D33.30
ICD-10 Finland
Acoustic neuroma
10.6
11.2
21
20
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
11.2
1430
12316
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
11.0
1067
8835
G47.3
ICD-10 Finland
Sleep apnoea
1.4
11.0
490
3563
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
10.9
1745
15467
SPAT1301
SPAT
No procedures
1.4
10.8
775
6129
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
7.2
10.7
25
35
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
21.5
10.7
15
7
RK530
NOMESCO Finland
NA
60.2
10.6
12
*
DC1AI
NOMESCO Finland
Cone beam CT of ear
60.2
10.6
12
*
S02.10
ICD-10 Finland
Fracture of base of skull, closed
8.0
10.6
23
29
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
10.5
1061
8824
R03AC02
ATC
salbutamol; inhalant
1.3
10.5
1374
11837
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
10.5
1152
9696
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
10.4
1237
10521
P20
ICPC
Memory disturbance
1.6
10.4
242
1516
H92.1
ICD-10 Finland
Otorrhoea
16.1
10.3
16
10
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.0
10.3
138
723
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
2.4
10.2
83
349
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
4.1
10.1
38
94
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
10.1
935
7669
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
9.9
182
1061
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
9.9
245
1560
N03AX16
ATC
pregabalin; oral
1.4
9.8
554
4205
4144
FHL
Mastoidectomy or aticomastoidectomy
20.1
9.8
14
7
DC1BD
NOMESCO Finland
Temporal bone extensive CT
20.1
9.8
14
7
N03AX12
ATC
gabapentin; oral
1.5
9.8
353
2455
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
10.6
9.8
18
17
DEB35
NOMESCO Finland
Radical mastoidectomy with tympanoplasty
55.2
9.6
11
*
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
15.1
9.5
15
10
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
100.3
9.4
10
*
DBD30
NOMESCO Finland
Correction of atresia of external auditory canal
100.3
9.4
10
*
N06AX11
ATC
mirtazapine; oral
1.3
9.4
769
6186
38990
ICD-8 Finland
Other deafness, Partialis uni-sive bilateralis
+∞
9.4
9
*
3851A
ICD-9 Finland
Other disorders of middle ear and mastoid, Adhesive middle ear disease
+∞
9.4
9
*
DDD30
NOMESCO Finland
Fixation of tympanic membrane to stapes
+∞
9.4
9
*
H91.0
ICD-10 Finland
Ototoxic hearing loss
+∞
9.4
9
*
S18
ICPC
Laceration/cut
1.3
9.3
1023
8567
J01DA08
ATC
[U] cefaclor; oral
1.5
9.3
292
1967
G44.2
ICD-10 Finland
Tension-type headache
1.5
9.3
300
2039
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
9.2
497
3740
M25.5
ICD-10 Finland
Pain in joint
1.3
9.0
684
5431
H02AB04
ATC
methylprednisolone; systemic
1.5
9.0
343
2416
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
8.9
512
3889
4451
FHL
Guitar cutting
2.3
8.9
77
336
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.0
8.9
104
519
R1260
NOMESCO Finland
Evaluation of communicative skills
3.1
8.8
47
155
J35.2
ICD-10 Finland
Hypertrophy of adenoids
2.6
8.8
64
254
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
8.8
1860
16851
M54.5
ICD-10 Finland
Low back pain
1.3
8.8
778
6319
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
8.7
615
4831
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
50.1
8.7
10
*
DCB00
NOMESCO Finland
Excision of lesion of middle ear
50.1
8.7
10
*
R01AD01
ATC
beclometasone; nasal
1.4
8.6
358
2561
R06.5
ICD-10 Finland
Mouth breathing
1.6
8.6
202
1268
M03BX02
ATC
tizanidine; oral
1.3
8.5
1567
13945
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
27.6
8.5
11
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
8.5
417
3081
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
8.5
368
2660
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
8.4
1369
12003
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
8.4
510
3910
Z45.3
ICD-10 Finland
Adjustment and management of implanted hearing device
+∞
8.3
8
*
75650
ICD-8 Finland
Other congenital anomalies of musculoskeletal system, Chondrodystrophy
+∞
8.3
8
*
38799
ICD-8 Finland
Other disease of ear and mastoid process, Other
+∞
8.3
8
*
L12
ICPC
Hand/finger symptom/complaint
1.5
8.3
330
2344
R05
ICPC
Cough
1.4
8.2
528
4079
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
8.2
577
4524
R05
ICD-10 Finland
Cough
1.4
8.0
443
3339
KMAK
NOMESCO Finland
NA
1.2
8.0
1313
11502
H60.4
ICD-10 Finland
Cholesteatoma of external ear
7.2
7.9
18
25
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
7.9
220
1444
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
7.9
174
1076
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
7.9
660
5306
DFF20
NOMESCO Finland
Audiometry for children
13.0
7.9
13
10
H72
ICD-10 Finland
Perforation of tympanic membrane
13.0
7.9
13
10
RK220
NOMESCO Finland
NA
6.1
7.8
20
33
M79.1
ICD-10 Finland
Myalgia
1.5
7.8
284
1977
Z98.8
ICD-10 Finland
Other specified postsurgical states
3.2
7.8
38
119
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
7.8
209
1361
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.7
7.8
142
831
SPAT1041
SPAT
Comprehensive hearing test
4.1
7.8
28
68
T16
ICD-10 Finland
Foreign body in ear
4.2
7.7
27
64
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.6
7.6
173
1079
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.6
462
3538
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
7.6
685
5564
DFX03
NOMESCO Finland
Review, maintenance and user education for hearing aid
25.1
7.6
10
*
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
7.5
976
8304
Z01.2
ICD-10 Finland
Dental examination
1.3
7.4
1039
8908
Q16.0
ICD-10 Finland
Congenital absence of (ear) auricle
80.3
7.4
8
*
H80.28
ICD-10 Finland
Cochlear otosclerosis
80.3
7.4
8
*
4146
FHL
Radical cutting (bridge broken)
80.3
7.4
8
*
Q78.08
ICD-10 Finland
Osteogenesis imperfecta tarda
80.3
7.4
8
*
H74.4
ICD-10 Finland
Polyp of middle ear
80.3
7.4
8
*
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.5
7.4
229
1542
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
7.4
368
2723
A28
ICPC
Limited function/disability NOS
1.5
7.4
294
2087
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
7.4
284
2003
RK240
NOMESCO Finland
NA
+∞
7.3
7
*
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
10.9
7.3
13
12
R00.1
ICD-10 Finland
Bradycardia, unspecified
2.2
7.3
71
328
R4130
NOMESCO Finland
Speech therapy
2.5
7.2
54
219
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
15.8
7.2
11
7
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
7.2
814
6798
T90.5
ICD-10 Finland
Sequelae of intracranial injury
3.4
7.2
32
94
4143
FHL
Atticotomy or atticoanthromy through the ear canal
30.1
7.1
9
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
7.1
403
3049
ZZG00
NOMESCO Finland
Graft of cartilage
12.0
7.1
12
10
SPAT1044
SPAT
Tympanometry
2.5
7.1
53
216
R06AE07
ATC
cetirizine; oral
1.2
7.0
1085
9396
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.0
1465
13102
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.6
7.0
171
1086
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
4.1
7.0
25
61
SPAT1153
SPAT
Removal of sutures
1.3
6.9
736
6094
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.3
6.9
480
3748
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
6.9
2502
23748
N17
ICPC
Vertigo/dizziness
1.5
6.9
227
1553
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.3
6.8
593
4786
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
6.8
938
8012
H03
ICPC
Tinnitus, ringing/buzzing ear
3.0
6.8
37
126
WX400
NOMESCO Finland
Inhalation anesthesy
1.8
6.8
106
591
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
6.8
138
838
R4110
NOMESCO Finland
Physiotherapy
1.3
6.7
642
5243
H70.0
ICD-10 Finland
Acute mastoiditis
16.7
6.7
10
6
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.0
6.7
82
420
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
6.7
767
6409
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.1
6.7
72
348
L03
ICPC
Low back symptom/complaint
1.3
6.7
544
4349
J45.1
ICD-10 Finland
Nonallergic asthma
1.6
6.7
165
1055
H02AB07
ATC
prednisone; oral
1.4
6.7
325
2398
R21
ICPC
Throat symptom/complaint
1.3
6.7
472
3698
L28
ICPC
Limited function/disability (L)
1.4
6.6
328
2429
E0000UV
ATC
NA
1.2
6.6
959
8238
H70
ICPC
Otitis externa
2.5
6.5
48
196
H69.0
ICD-10 Finland
Patulous Eustachian tube
4.8
6.5
20
42
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
6.5
519
4135
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.4
6.5
252
1783
H91.3
ICD-10 Finland
Deaf mutism, not elsewhere classified
70.0
6.4
7
*
M01AE02
ATC
naproxen; oral, rectal
1.2
6.4
1456
13088
R06AX27
ATC
desloratadine; oral
1.3
6.4
644
5293
UKC02
NOMESCO Finland
Cystoscopy
1.4
6.4
329
2448
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
6.4
1053
9160
Z31.5
ICD-10 Finland
Genetic counselling
1.7
6.4
117
687
J02AC01
ATC
fluconazole; systemic
1.2
6.4
957
8238
R03BA02
ATC
budesonide; inhalant
1.3
6.4
405
3122
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
6.3
638
5240
SPAT1053
SPAT
Memory test
1.4
6.3
273
1971
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.9
6.3
86
458
R13
ICD-10 Finland
Dysphagia
1.6
6.2
138
858
SPAT1216
SPAT
Assessment of functional ability
1.4
6.2
316
2345
4129
FHL
Other measure in this category
26.7
6.2
8
*
DE2BM
NOMESCO Finland
Acoustic channel MRI examination with 3 Tesla magnet
26.7
6.2
8
*
J01DA06
ATC
[U] cefuroxime; systemic
1.4
6.2
342
2578
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
6.2
1445
13004
A02BC01
ATC
omeprazole; systemic
1.3
6.2
632
5198
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
6.2
419
3261
M02AA07
ATC
piroxicam; topical
1.2
6.2
837
7124
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
6.2
403
3118
D07AC13
ATC
mometasone; topical
1.3
6.1
662
5483
R12
ICD-10 Finland
Heartburn
1.6
6.1
154
988
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
3.4
6.1
27
80
D07AC01
ATC
betamethasone; topical
1.2
6.1
802
6799
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.2
6.1
740
6217
Z01.9
ICD-10 Finland
Special examination, unspecified
1.7
6.1
123
744
S82
ICPC
Naevus/mole
1.4
6.1
269
1952
J01FA09
ATC
clarithromycin; systemic
1.2
6.1
752
6328
SPAT1312
SPAT
General health counselling
1.2
6.1
780
6593
RK510
NOMESCO Finland
NA
12.5
6.1
10
8
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
6.1
721
6044
R49.01
ICD-10 Finland
Functional dysphonia
2.1
6.1
65
315
Z97.8
ICD-10 Finland
Presence of other specified devices
8.6
6.0
12
14
H25.8
ICD-10 Finland
Other senile cataract
1.5
6.0
198
1355

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
605
3144
2.12
55.41
2.1
1.7
—
—
—
0
0
2329
20233
1.47
23.44
4.3
4.0
12.1
11.9
mm/h
0.21
2174
18734
1350
10697
1.43
21.83
2.0
2.0
96.3
94.8
pmol/l
0.48
689
5566
1486
12053
1.41
20.73
6.9
6.1
1.2
1.2
mmol/l
0.67
1362
10958
2381
20992
1.44
20.43
7.6
7.4
77.5
78.9
u/l
0.74
2236
19818
3046
28340
1.67
19.57
17.8
15.4
139.8
139.7
mmol/l
2.58
2979
27626
3051
28426
1.67
19.15
18.0
15.5
4.0
4.0
mmol/l
0.29
2982
27658
1596
13310
1.37
17.90
7.3
6.8
1.2
1.2
mmol/l
0.52
1376
11264
1066
8345
1.40
17.45
2.8
2.6
56.6
57.6
u/l
0.24
988
7715
3135
29551
1.72
17.15
11.1
10.1
26.1
26.5
u/l
0.54
3031
28571
2865
26449
1.51
17.11
4.6
4.3
5.9
5.9
mmol/l
0.86
2621
24214
2770
25409
1.47
16.99
5.1
4.6
1.9
2.1
mu/l
1.37
2543
23386
2390
21391
1.39
16.54
4.3
3.9
14.7
14.7
pmol/l
0.28
2181
19542
2979
27802
1.55
16.16
15.6
13.6
22.6
23.7
mg/l
1.04
2386
21885
2138
18846
1.36
15.95
4.7
4.2
—
—
—
0
0
3082
29031
1.61
15.56
14.6
12.6
—
—
—
0
0
1842
15933
1.34
15.25
5.5
4.7
6.6
6.7
mmol/l
0.43
1726
14852
1193
9700
1.35
14.88
3.8
3.4
41.8
98.3
ng/l
0.59
758
6371
526
3760
1.47
13.76
1.9
2.1
—
—
—
0
0
3247
31134
1.82
13.74
22.9
19.9
252.9
253.0
e9/l
0.04
3171
30349
776
5956
1.39
13.69
1.6
1.5
21.1
20.4
nmol/l
0.61
663
5122
3248
31152
1.82
13.65
22.7
19.9
90.8
90.8
fl
0.11
3204
30732
3248
31154
1.82
13.62
22.7
19.8
30.2
30.3
pg
0.21
3203
30731
3248
31158
1.82
13.55
22.8
19.9
4.5
4.5
e12/l
1.03
3167
30294
3248
31167
1.81
13.41
22.9
20.0
6.7
6.7
e9/l
0.38
3167
30295
3248
31168
1.81
13.40
23.0
20.0
134.8
135.4
g/l
1.44
3202
30743
2026
17961
1.31
13.15
4.6
4.3
1057.5
1589.4
e6/l
0.26
28
244
1663
14400
1.30
12.63
6.6
6.2
0.2
0.2
e9/l
0.11
1494
12595
983
7935
1.33
12.35
2.3
2.1
215.1
228.0
u/l
0.15
919
7461
1624
14072
1.29
12.05
6.3
6.2
10.8
11.4
umol/l
1.06
1540
13348
1328
11210
1.30
12.02
2.5
2.3
76.7
76.6
nmol/l
0.07
1196
10141
1256
10524
1.31
12.02
8.2
9.2
1.2
1.2
inr
2.11
334
3079
2679
24855
1.36
11.86
5.8
5.5
39.4
39.6
mmol/mol
0.39
2476
23111
1600
13885
1.29
11.54
6.3
5.9
0.6
0.6
e9/l
0.63
1423
11939
1605
13936
1.29
11.52
6.4
6.0
0.0
0.0
e9/l
0.36
1427
11983
1237
10388
1.30
11.50
3.5
3.2
—
5.8
—
0
9
437
3136
1.45
11.07
1.5
1.4
—
—
—
0
0
1636
14323
1.27
10.67
6.4
6.0
1.9
1.9
e9/l
1.56
1487
12574
2049
18446
1.28
10.58
3.3
3.1
44.5
47.4
u/l
0.86
1917
17256
611
4684
1.37
10.56
1.7
1.7
1160.9
1168.7
nmol/l
0.07
453
3555
1505
13107
1.26
10.03
6.6
6.1
2.9
2.8
%
0.36
1419
12233
1512
13178
1.26
10.00
6.9
6.4
8.7
8.6
%
0.67
1430
12354
871
7090
1.31
9.93
3.3
3.0
1527.1
1446.5
ng/l
0.15
727
6071
604
4667
1.36
9.87
1.3
1.3
30.6
32.4
iu/ml
0.09
171
1486
961
7941
1.29
9.75
4.1
4.0
7.4
7.4
ph
0.23
148
1514
2907
27536
1.37
9.58
5.1
4.7
2.8
2.8
mmol/l
0.10
2686
25481
1462
12735
1.26
9.58
6.6
6.2
0.7
0.7
%
0.37
1372
11895
494
3716
1.38
9.53
1.4
1.3
611.1
524.9
titre
0.42
94
774
1524
13369
1.25
9.29
6.4
6.0
56.7
56.9
%
0.29
1437
12542
572
4428
1.35
9.19
1.4
1.2
11.2
11.4
u/ml
0.02
220
1712
2089
19023
1.25
9.00
3.9
3.6
—
—
—
0
0
1334
11574
1.25
8.82
4.9
5.0
35.8
35.6
g/l
0.71
1234
10776
771
6274
1.30
8.64
1.3
1.3
2.0
1.7
u/ml
0.19
223
1628
1537
13570
1.24
8.61
6.6
6.2
28.4
28.3
%
0.13
1444
12675
1106
9416
1.26
8.57
6.3
6.1
—
—
—
0
0
1514
13350
1.24
8.57
3.8
3.5
0.0
0.0
estimate
0.50
230
2469
2744
25884
1.30
8.47
4.0
3.8
1.3
1.3
mmol/l
0.22
2525
23847
1515
13380
1.24
8.38
5.3
4.7
0.0
0.0
estimate
0.50
245
2544
2833
26861
1.32
8.26
4.5
4.2
1.5
1.5
mmol/l
0.23
2607
24888
2851
27056
1.32
8.26
4.5
4.2
4.7
4.7
mmol/l
0.09
2648
25204
884
7356
1.27
8.25
4.0
3.7
—
—
—
0
0
1529
13535
1.23
8.22
3.9
3.5
0.0
0.0
estimate
1.06
238
2457
739
6017
1.29
8.20
2.2
1.8
1.3
1.2
mg/l
0.60
576
4546
1061
9035
1.25
8.11
3.1
3.4
2.4
2.4
mmol/l
0.24
905
7956
1027
8718
1.25
8.06
2.4
2.4
—
—
—
0
0
684
5527
1.30
8.03
1.7
1.5
2.5
2.4
g/l
0.68
419
3354
837
6940
1.27
8.01
2.7
2.7
2541.7
4701.9
umol/l
1.40
720
6079
1790
16146
1.23
7.93
8.9
9.2
4.0
4.1
e9/l
0.62
1585
14030
448
3425
1.35
7.74
2.2
2.4
102.5
131.9
ug/g
1.35
341
2716
769
6334
1.28
7.73
3.7
3.4
—
—
—
0
0
947
8030
1.25
7.38
3.2
3.0
—
—
—
0
0
436
3353
1.34
7.24
9.2
7.0
104.6
104.4
mmol/l
0.27
424
3277
162
1033
1.60
7.19
1.3
1.2
0.3
0.9
u/ml
1.15
15
84
1460
12983
1.22
7.17
4.2
4.0
—
—
—
0
0
853
7184
1.25
7.01
4.5
4.3
—
—
—
0
0
343
2559
1.38
6.91
5.5
4.2
2.0
1.9
mmol/l
0.20
279
2064
2498
23499
1.23
6.69
19.0
16.6
13.7
13.6
%
0.14
2453
22980
852
7214
1.24
6.62
7.1
6.8
—
—
—
0
0
341
2560
1.37
6.61
5.5
4.2
5.9
5.8
kpa
0.65
331
2484
468
3683
1.31
6.60
1.2
1.2
—
—
—
0
0
349
2631
1.36
6.59
5.5
4.2
—
7.4
—
0
13
788
6654
1.24
6.23
2.4
2.3
—
—
—
0
0
1361
12152
1.20
6.09
3.0
2.8
108.4
118.4
ug/l
0.76
1270
11291
2718
25889
1.24
6.01
17.3
14.6
39.4
39.9
%
1.98
1994
19189
802
6833
1.23
5.77
2.3
2.3
2.9
2.9
mg/l
0.01
690
5827
695
5836
1.24
5.74
4.2
3.8
1.0
1.0
kg/l
0.23
96
864
1104
9717
1.20
5.68
4.0
3.7
134.3
98.5
e6/l
0.39
777
6821
881
7596
1.22
5.62
3.4
3.1
0.4
0.4
e6/l
0.55
665
5716
2548
24162
1.21
5.60
20.2
17.3
332.4
332.5
g/l
0.15
2526
23976
1243
11074
1.19
5.56
2.2
2.1
—
—
—
0
0
281
2105
1.36
5.54
5.8
3.5
4.4
4.6
kpa
1.48
271
2036
172
1182
1.48
5.50
5.4
2.8
0.7
0.7
%
0.09
164
1138
565
4664
1.25
5.42
2.9
2.7
1.3
1.1
e6/l
0.47
328
2624
175
1211
1.47
5.41
5.4
2.9
1.2
1.3
%
0.12
175
1202
96
589
1.65
5.08
4.0
3.5
—
—
—
0
0
961
8428
1.19
5.03
3.2
3.2
7.3
7.6
mmol/l
1.14
797
7152
533
4410
1.25
4.99
3.8
3.6
0.8
0.8
mmol/l
0.32
495
4126
189
1349
1.42
4.98
2.5
2.3
—
—
—
0
0
941
8254
1.19
4.89
3.5
3.2
33.2
78.0
e6/l
3.72
733
6322
173
1221
1.44
4.86
4.2
3.4
25.4
25.3
mmol/l
0.10
166
1181
618
5214
1.23
4.82
3.9
3.6
377.0
634.4
ng/l
0.54
480
3949
1373
12457
1.17
4.74
9.8
9.3
0.0
0.0
e9/l
0.66
1120
10129
157
1098
1.45
4.64
2.1
1.5
11.9
18.4
u/ml
—
8
31
501
4168
1.24
4.45
2.6
2.5
13.4
13.3
umol/l
0.23
466
3871
498
4141
1.24
4.45
2.7
2.3
29.7
29.8
s
0.09
486
4024
393
3183
1.27
4.42
3.0
2.8
6.8
8.0
umol/l
0.66
337
2762
623
5304
1.21
4.42
3.0
2.7
553.9
551.0
mosm/kgh2o
0.10
525
4516
45
230
1.97
4.39
1.4
1.4
12.3
12.5
mmol/l
—
10
54
244
1857
1.34
4.38
2.5
2.3
25.8
23.7
au/ml
—
9
115
148
1037
1.45
4.35
3.6
5.6
1.6
1.6
%
0.22
138
962
340
2712
1.28
4.34
8.1
7.9
95.7
95.7
%
0.02
325
2612
323
2561
1.29
4.32
4.2
4.3
—
—
—
0
0
299
2347
1.30
4.32
10.2
8.5
—
—
—
0
0
821
7196
1.19
4.22
1.7
1.6
1.4
1.4
mmol/l
0.23
692
6109
223
1689
1.34
4.15
1.3
1.3
26.3
45.5
au/ml
—
10
69
82
511
1.62
4.15
3.4
3.2
7.6
7.4
mmol/l
0.16
82
497
433
3573
1.24
4.15
2.7
2.6
22.5
23.0
%
0.31
365
3080
86
545
1.59
4.07
3.3
3.1
1.6
1.5
mmol/l
0.20
86
527
881
7790
1.18
4.06
4.9
4.7
2.6
2.8
ug/l
0.20
786
6984
460
3830
1.23
4.05
2.6
2.5
2.4
2.3
g/l
0.47
421
3545
638
5488
1.20
4.04
1.7
1.7
37454300.8
25600950.1
pmol/l
0.22
542
4621
363
2945
1.26
4.04
3.1
2.8
1.8
1.8
%
0.23
325
2627
844
7444
1.18
4.01
3.3
3.0
—
—
—
0
0
239
1840
1.32
3.99
1.6
1.4
—
—
—
0
0
286
2258
1.29
3.97
1.1
1.2
—
—
—
0
0
113
768
1.49
3.92
3.6
3.3
1.4
2.3
ratio
0.51
15
58
144
1029
1.42
3.85
3.6
5.7
0.9
0.9
%
0.26
133
958
65
391
1.68
3.80
1.4
1.4
32.8
25.1
u/l
1.03
51
328
190
1426
1.35
3.78
6.2
4.7
24.3
24.1
mmol/l
0.42
165
1304
45
244
1.86
3.74
1.6
1.6
—
—
—
0
0
115
793
1.47
3.72
4.0
3.4
75.8
129.6
mg/l
0.31
101
643
115
794
1.46
3.70
4.0
3.4
29.3
62.1
mg/l
1.26
102
644
274
2176
1.28
3.65
2.8
2.7
71.8
70.4
e9/l
0.18
206
1615
315
2549
1.26
3.60
2.4
2.2
353.1
373.6
nmol/l
1.23
295
2338
655
5706
1.18
3.58
2.7
2.6
5.4
6.2
e6/l
0.61
565
5004
48
271
1.78
3.53
3.9
3.5
—
—
—
0
0
368
3040
1.24
3.50
7.9
7.5
1.4
1.1
mmol/l
0.49
296
2384
244
1920
1.29
3.50
2.4
2.2
13.1
12.6
nmol/l
0.38
211
1690
309
2511
1.25
3.42
8.4
8.2
121.7
122.1
g/l
0.14
295
2419
368
3049
1.23
3.41
7.8
7.5
12.9
12.5
kpa
0.64
352
2904
511
4380
1.20
3.35
3.1
2.9
2.7
2.6
e6/l
0.04
276
2353
92
622
1.49
3.32
5.0
4.0
—
—
—
0
0
367
3049
1.23
3.32
7.9
7.5
5.1
5.1
kpa
0.15
351
2903
51
299
1.72
3.32
2.4
2.4
—
—
—
0
0
59
360
1.65
3.31
2.5
2.3
6.3
4.9
umol/l
0.38
44
259
39
211
1.86
3.30
2.8
2.3
16.9
11.8
%
1.42
20
101
221
1738
1.29
3.21
3.1
2.3
—
—
—
0
0
157
1183
1.34
3.10
1.1
1.1
16.1
1.3
u/ml
—
5
16
39
216
1.81
3.09
2.8
2.3
69.8
72.6
%
0.46
39
204
396
3343
1.21
3.06
24.5
23.2
1.4
1.3
inr
0.27
45
494
113
810
1.41
3.04
1.9
2.8
—
—
—
0
0
46
270
1.71
3.01
2.6
2.5
1.0
1.1
e9/l
0.41
33
168
270
2195
1.25
3.00
3.1
2.8
149.2
200.7
ng/l
2.45
245
1986
238
1909
1.27
2.97
2.8
3.0
3.9
4.1
e9/l
0.76
181
1535
114
822
1.40
2.97
3.4
3.2
—
—
—
0
0
199
1562
1.29
2.95
1.3
1.2
—
—
—
0
0
258
2094
1.25
2.92
3.8
2.7
10.6
10.5
g/l
0.16
238
1910
219
1744
1.27
2.91
1.4
1.3
156.8
212.9
u/ml
0.98
201
1610
147
1109
1.34
2.90
1.1
1.2
—
—
—
0
0
892
8072
1.14
2.90
4.1
4.0
9.1
8.8
mg/mmol
0.06
542
5143
422
3614
1.19
2.81
6.3
6.2
1.0
1.1
mmol/l
0.47
395
3362
8
18
4.45
2.79
1.4
1.3
—
—
—
0
0
266
2182
1.24
2.75
2.3
2.3
6.0
7.2
ug/l
1.03
221
1928
205
1633
1.27
2.73
2.5
1.8
1.3
1.3
g/l
0.06
188
1485
38
219
1.74
2.68
8.6
3.7
10.1
11.3
%
0.84
38
219
344
2906
1.20
2.66
1.3
1.3
—
—
—
0
0
203
1622
1.27
2.65
5.6
7.2
24.9
24.6
mmol/l
0.43
186
1505
78
537
1.46
2.65
1.9
2.5
—
—
—
0
0
132
1000
1.33
2.57
1.1
1.1
—
—
—
0
0
287
2393
1.22
2.55
10.3
7.1
1.3
1.3
mmol/l
0.21
277
2301
549
4844
1.16
2.54
2.9
3.0
2.5
2.5
mmol/l
0.13
469
4243
26
136
1.92
2.50
1.3
1.3
161.6
336.9
u/l
1.25
26
125
113
1496
0.75
2.43
1.6
1.7
—
—
—
0
0
107
794
1.36
2.41
1.4
1.4
287.5
277.8
ug/g
0.16
61
453
213
1739
1.24
2.34
10.8
7.7
24.9
24.9
mmol/l
0.02
208
1732
86
619
1.40
2.33
1.9
1.6
14553.3
12660.7
e6/l
0.15
64
447
15
65
2.31
2.31
1.3
1.1
—
—
—
0
0
122
931
1.32
2.29
1.6
2.0
—
—
—
0
0
107
804
1.34
2.24
1.5
1.5
9.7
10.0
u/l
0.07
86
643
256
2141
1.21
2.24
3.4
2.6
67.0
66.5
g/l
0.45
234
1960
167
1334
1.26
2.23
4.3
3.1
—
—
—
0
0
140
1096
1.29
2.20
1.7
2.0
—
—
—
0
0
15
67
2.24
2.17
1.2
1.1
—
—
—
0
0
23
123
1.88
2.11
2.4
2.0
31.6
27.9
umol/l
0.59
23
117
838
7691
1.12
2.11
3.4
3.3
131.2
300.0
mg/l
1.20
518
4918
220
1825
1.22
2.10
1.3
1.2
—
—
—
0
0
131
1024
1.29
2.10
6.3
4.6
—
—
—
0
0
35
214
1.64
2.06
1.2
1.2
—
—
—
0
0
42
269
1.57
2.06
2.0
1.9
—
—
—
0
0
178
1448
1.24
2.05
10.3
10.2
—
—
—
0
0
67
474
1.42
2.04
1.5
1.5
—
—
—
0
0
241
2024
1.21
2.04
4.2
4.1
83.1
87.9
ng/l
0.34
213
1767
287
2453
1.19
2.01
8.3
7.8
9.5
9.5
mmol/l
0.07
273
2348
37
233
1.59
1.96
1.3
1.2
—
—
—
0
0
102
779
1.32
1.95
3.8
4.3
3.9
3.9
mmol/l
0.04
90
724
5
11
4.55
1.94
1.2
1.7
158.4
200.6
ng/l
—
5
11
147
1179
1.26
1.94
1.7
2.0
—
—
—
0
0
60
423
1.43
1.89
1.7
1.4
—
—
—
0
0
205
1710
1.21
1.88
3.9
5.1
—
—
—
0
0
147
1184
1.25
1.88
1.7
2.0
—
—
—
0
0
28
166
1.69
1.87
5.0
3.6
—
—
—
0
0
119
936
1.28
1.85
2.1
2.3
9.9
10.3
g/l
0.48
101
804
79
587
1.35
1.84
4.1
7.6
11.0
11.1
mmol/l
0.08
69
520
208
1743
1.21
1.83
3.5
3.3
4.5
4.5
pmol/l
0.10
187
1552
34
214
1.59
1.82
1.1
1.2
—
242.9
—
0
7
34
214
1.59
1.82
1.1
1.2
60.0
176.7
titre
—
6
45
79
588
1.35
1.82
4.1
7.6
104.6
105.3
mmol/l
0.65
69
521
174
1434
1.22
1.81
12.1
9.5
24.3
24.3
mmol/l
0.08
160
1350
20
108
1.86
1.81
3.8
2.7
28.3
29.3
%
0.11
20
101
40
262
1.53
1.81
1.4
1.3
—
—
—
0
0
100
773
1.30
1.78
1.2
1.3
101.3
92.2
titre
—
8
65
302
2625
1.17
1.75
1.4
1.4
—
—
—
0
0
144
1168
1.24
1.75
1.7
1.8
1.6
1.5
g/l
0.54
130
1020
99
769
1.30
1.72
1.3
1.2
—
—
—
0
0
78
587
1.34
1.69
2.0
1.6
—
—
—
0
0
17
306
0.55
1.68
2.6
2.4
—
—
—
0
0
66
485
1.37
1.67
1.0
1.1
—
—
—
0
0
104
819
1.28
1.64
3.8
6.6
1.3
1.2
mmol/l
0.13
89
712
39
261
1.50
1.63
1.3
1.3
0.4
0.4
g/l
0.04
27
187
39
261
1.50
1.63
1.3
1.3
3.1
3.0
g/l
0.13
27
187
39
261
1.50
1.63
1.3
1.3
7.5
6.7
g/l
0.55
27
186
19
105
1.81
1.62
1.7
1.9
—
—
—
0
0
116
928
1.26
1.61
2.9
3.5
0.4
0.3
g/l
0.44
50
408
82
627
1.32
1.61
1.9
1.6
209.5
1329.0
e6/l
1.54
71
505
20
113
1.77
1.60
3.7
2.9
13.8
10.8
%
0.46
20
105
114
912
1.26
1.59
2.6
2.4
385.7
519.3
ug/l
0.38
105
852
115
921
1.26
1.59
1.4
1.3
183.5
224.6
miu/ml
0.70
51
433
143
1174
1.23
1.58
1.7
2.0
—
—
—
0
0
16
287
0.56
1.57
1.1
1.1
—
—
—
0
0
48
340
1.42
1.52
1.6
1.5
—
—
—
0
0
126
1026
1.24
1.51
2.1
2.0
1.9
2.2
ug/l
0.10
108
910
133
1090
1.23
1.51
4.3
4.3
25.1
24.8
mmol/l
0.72
126
1015
117
946
1.25
1.50
2.9
2.5
—
—
—
0
0
58
426
1.37
1.50
1.7
1.2
103.5
45.9
u/l
0.75
49
368
81
626
1.30
1.49
1.9
1.6
53.6
32.0
e6/l
0.31
65
479
140
1156
1.22
1.48
1.7
1.9
—
—
—
0
0
246
2139
1.16
1.46
3.8
3.4
—
—
—
0
0
395
3549
1.13
1.45
1.3
1.3
—
—
—
0
0
9
38
2.37
1.45
2.1
1.6
—
—
—
0
0
20
117
1.71
1.44
3.6
3.0
—
—
—
0
0
223
1926
1.17
1.44
1.2
1.2
166.5
150.2
iu/ml
0.21
88
718
376
3370
1.13
1.44
1.7
1.6
—
—
—
0
0
26
164
1.59
1.43
1.7
2.3
0.2
0.2
e9/l
0.02
26
158
150
1253
1.21
1.42
3.9
4.1
—
—
—
0
0
19
110
1.73
1.42
1.7
1.9
8.7
8.5
%
0.01
19
105
35
237
1.48
1.41
2.9
2.3
55.2
45.3
%
—
5
24
107
869
1.24
1.35
13.2
9.2
—
—
—
0
0
89
710
1.26
1.31
1.4
1.2
1.4
8.1
u/ml
0.83
11
67
39
275
1.42
1.30
1.6
1.4
282.0
281.3
mosm/kgh2o
0.08
34
209
764
7145
1.09
1.30
4.3
3.8
0.0
0.0
estimate
1.34
240
2454
21
129
1.63
1.29
3.4
2.9
—
—
—
0
0
14
76
1.85
1.29
1.1
1.2
40.8
38.0
g/l
—
7
43
761
7120
1.09
1.28
4.6
4.0
89.8
90.3
%
0.23
744
6944
22
342
0.64
1.28
1.1
1.0
0.5
0.3
u/ml
—
6
90
75
588
1.28
1.28
6.6
3.3
—
—
—
0
0
19
114
1.67
1.28
2.6
3.0
—
—
—
0
0
776
7269
1.09
1.27
3.5
3.1
—
—
—
0
0
6
25
2.40
1.24
1.7
1.5
0.6
0.4
%
—
6
15
8
36
2.23
1.24
1.1
1.1
—
—
—
0
0
585
5419
1.10
1.23
1.9
1.9
—
—
—
0
0
101
826
1.23
1.22
1.2
1.2
—
—
—
0
0
46
339
1.36
1.21
1.6
1.5
—
—
—
0
0
27
180
1.50
1.20
1.1
1.0
—
—
—
0
0
148
1259
1.18
1.19
1.7
1.9
—
—
—
0
0
13
71
1.83
1.19
2.2
2.3
—
—
—
0
0
497
4578
1.10
1.19
2.9
3.0
0.7
0.8
ug/l
2.20
308
3022
67
524
1.28
1.18
2.2
1.7
—
—
—
0
0
6
26
2.31
1.18
1.5
1.3
—
—
—
0
0
76
604
1.26
1.18
1.6
1.3
256.9
255.7
u/ml
0.01
55
365
43
315
1.37
1.18
1.3
1.5
67.9
59.8
%
0.70
23
201
22
141
1.56
1.17
2.5
1.7
—
—
—
0
0
10
185
0.54
1.15
21.5
18.1
1785.2
1510.8
nmol/l
—
10
180
125
1052
1.20
1.15
1.6
1.6
—
—
—
0
0
71
563
1.27
1.14
4.0
3.8
56.5
56.7
%
0.03
71
563
92
752
1.23
1.13
1.7
1.8
45.2
39.5
nmol/l
1.22
87
729
15
88
1.71
1.11
1.2
1.3
—
—
—
0
0
97
800
1.22
1.10
1.9
2.1
37.6
37.9
g/l
0.24
83
700
10
182
0.55
1.10
13.5
13.0
963.4
851.9
nmol/l
—
10
174
5
21
2.38
1.09
1.0
1.1
—
—
—
0
0
54
416
1.30
1.09
2.4
1.3
—
—
—
0
0
336
3050
1.11
1.08
1.8
1.7
—
—
—
0
0
45
592
0.76
1.07
1.4
1.5
—
—
—
0
0
13
74
1.76
1.06
5.7
1.3
—
—
—
0
0
7
33
2.12
1.05
7.4
10.3
—
—
—
0
0
21
137
1.54
1.05
1.6
1.6
—
9.5
—
0
7
70
561
1.25
1.05
1.4
1.3
—
—
—
0
0
32
229
1.40
1.03
2.7
2.8
25.9
38.0
mg/l
0.31
23
162
19
123
1.55
0.99
2.8
2.0
2.3
1.9
umol/l
0.81
19
117
147
1274
1.16
0.99
1.4
1.4
30.8
28.5
iu/l
0.32
124
1057
5
23
2.18
0.98
1.4
1.7
—
—
—
0
0
22
148
1.49
0.97
1.6
1.3
134.1
135.3
nmol/l
0.06
22
148
9
50
1.80
0.96
1.1
1.2
—
—
—
0
0
9
50
1.80
0.96
1.1
1.2
—
—
—
0
0
9
50
1.80
0.96
1.1
1.2
—
—
—
0
0
22
149
1.48
0.95
2.0
2.2
—
—
—
0
0
6
27
2.22
0.93
1.7
1.5
—
—
—
0
0
9
52
1.73
0.92
1.4
2.8
—
—
—
0
0
45
577
0.78
0.92
1.3
1.4
—
—
—
0
0
37
487
0.76
0.92
1.0
1.2
—
—
—
0
0
6
28
2.14
0.91
1.2
1.1
—
—
—
0
0
45
575
0.78
0.90
1.3
1.4
—
—
—
0
0
71
582
1.22
0.90
3.6
3.4
28.6
27.5
mg/l
0.08
44
359
14
219
0.64
0.90
1.0
1.1
—
—
—
0
0
54
432
1.25
0.86
2.1
1.5
—
—
—
0
0
74
613
1.21
0.86
1.8
1.4
—
—
—
0
0
39
299
1.31
0.86
2.9
2.0
—
—
—
0
0
22
153
1.44
0.85
2.2
2.6
36.3
41.0
%
0.46
12
48
6
31
1.94
0.84
1.2
1.1
—
—
—
0
0
6
31
1.94
0.84
1.0
1.3
—
—
—
0
0
15
96
1.56
0.84
1.0
1.2
—
—
—
0
0
43
336
1.28
0.83
1.3
1.4
304.4
285.7
pmol/l
0.12
33
263
29
214
1.36
0.82
1.3
1.2
—
46.2
—
0
13
49
390
1.26
0.82
2.5
2.0
—
3.7
—
0
8
6
32
1.88
0.81
1.2
1.0
23.8
1.4
u/ml
—
6
22
6
32
1.88
0.81
1.0
1.1
—
—
—
0
0
942
9817
0.94
0.80
3.0
2.7
—
—
—
0
0
83
702
1.19
0.79
1.9
1.9
2.7
5.1
iu/l
3.73
34
252
68
565
1.21
0.78
3.3
2.9
34.7
36.2
umol/l
0.14
63
483
14
90
1.56
0.78
3.9
2.2
—
—
—
0
0
42
331
1.27
0.77
2.6
2.4
—
—
—
0
0
32
243
1.32
0.77
1.4
1.4
137611.9
59373.7
e6/l
0.26
16
164
20
140
1.43
0.76
2.1
1.6
28.9
25.6
umol/l
0.17
20
130
67
558
1.20
0.76
1.9
1.4
109.8
116.0
u/ml
0.19
14
100
24
175
1.37
0.74
1.3
1.2
—
—
—
0
0
191
1726
1.11
0.73
4.4
4.0
5.2
5.2
kpa
0.06
178
1603
18
125
1.44
0.72
1.6
2.0
27.1
268.1
ug/l
0.66
18
113
7
40
1.75
0.71
1.3
1.2
5.2
4.9
nmol/l
—
7
40
53
435
1.22
0.71
1.4
1.6
1.0
0.8
g/l
0.21
41
340
5
26
1.92
0.70
1.2
1.2
—
—
—
0
0
475
4479
1.07
0.70
1.6
1.6
—
—
—
0
0
214
2343
0.91
0.70
3.8
3.7
—
—
—
0
0
122
1078
1.14
0.69
3.2
2.5
20.9
21.5
s
0.91
109
947
188
1705
1.11
0.69
4.4
4.0
7.4
7.4
ph
0.02
16
199
196
1782
1.11
0.68
3.4
2.8
—
—
—
0
0
10
61
1.64
0.68
1.6
3.0
—
—
—
0
0
292
2708
1.09
0.67
2.6
2.4
35.0
56.5
u/l
0.63
251
2321
5
92
0.54
0.67
1.2
2.3
1669.2
792.1
e6/l
—
5
68
7
43
1.63
0.66
1.3
1.0
—
—
—
0
0
250
2707
0.92
0.65
1.3
1.3
—
—
—
0
0
49
403
1.22
0.65
4.9
5.3
381.7
366.9
umol/l
0.30
42
347
7
44
1.59
0.65
1.0
1.2
—
—
—
0
0
39
313
1.25
0.65
1.2
1.2
—
—
—
0
0
116
1028
1.13
0.64
1.9
1.6
316.8
298.5
mu/l
0.27
107
926
46
377
1.22
0.64
1.6
1.8
—
—
—
0
0
43
350
1.23
0.63
1.3
1.5
23.2
53.8
mu/l
2.58
38
316
41
332
1.24
0.63
1.6
1.3
—
—
—
0
0
50
414
1.21
0.63
1.2
1.2
—
—
—
0
0
35
279
1.26
0.62
5.2
4.4
—
—
—
0
0
8
50
1.60
0.61
5.1
3.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
54
454
1.19
0.59
1.4
1.5
—
—
—
0
0
34
272
1.25
0.59
1.1
1.1
—
—
—
0
0
46
381
1.21
0.59
1.1
1.1
—
—
—
0
0
25
192
1.30
0.59
2.0
2.5
780.5
680.4
e6/l
—
10
73
25
192
1.30
0.59
1.0
1.1
7.2
10.8
iu/ml
—
5
48
11
72
1.53
0.59
1.5
1.3
36.8
29.3
%
—
6
50
8
53
1.51
0.58
1.5
1.9
—
—
—
0
0
830
8004
1.05
0.58
1.4
1.5
—
—
—
0
0
13
89
1.46
0.58
4.5
2.8
152.5
170.2
e6/l
—
8
50
237
2198
1.08
0.57
1.6
1.4
—
—
—
0
0
12
81
1.48
0.57
1.3
1.3
—
—
—
0
0
20
150
1.34
0.55
1.1
1.2
—
—
—
0
0
38
311
1.22
0.55
1.2
1.3
—
—
nmol/l
—
0
0
16
217
0.74
0.55
1.3
1.3
2.2
2.1
mmol/l
0.13
16
208
647
6213
1.05
0.54
5.2
4.4
—
—
—
0
0
54
459
1.18
0.54
1.2
1.3
—
—
—
0
0
29
231
1.26
0.53
1.6
1.5
31.5
34.7
%
0.16
13
140
23
178
1.29
0.53
1.2
1.2
—
—
—
0
0
36
295
1.22
0.52
6.4
5.3
7.4
7.5
mmol/l
0.07
31
251
42
350
1.20
0.52
3.5
2.6
—
—
—
0
0
120
1084
1.11
0.51
1.8
2.3
4404.8
4123.2
u/l
0.06
38
430
40
333
1.20
0.51
1.2
1.3
—
—
—
0
0
110
991
1.11
0.50
1.5
1.3
—
—
—
0
0
10
67
1.49
0.49
2.1
2.1
—
—
—
0
0
25
199
1.26
0.48
1.1
1.1
—
—
—
0
0
7
47
1.49
0.47
1.6
1.4
—
—
—
0
0
30
245
1.23
0.46
1.1
1.1
—
—
—
0
0
37
440
0.84
0.46
1.3
1.3
7.1
4.0
u/ml
0.38
16
193
50
430
1.17
0.46
1.3
1.5
0.3
0.4
nmol/l
0.78
42
333
21
265
0.79
0.45
1.6
1.5
—
—
—
0
0
33
396
0.83
0.45
1.0
1.1
4.1
3.1
u/ml
0.24
13
180
22
174
1.27
0.44
1.3
1.1
—
—
—
0
0
276
2606
1.06
0.44
2.3
2.4
0.2
0.2
g/l
0.57
247
2431
26
211
1.23
0.43
2.3
2.3
—
—
—
0
0
19
148
1.29
0.43
2.5
3.0
7.4
7.4
ph
—
5
53
85
764
1.12
0.42
8.5
5.4
1.5
1.5
mg/l
0.29
76
707
17
131
1.30
0.42
25.6
26.8
100.3
122.4
ug/l
0.89
12
109
10
70
1.43
0.41
1.2
1.4
—
—
—
0
0
5
33
1.52
0.41
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
16
123
1.30
0.40
1.1
1.1
—
—
—
0
0
55
483
1.14
0.40
1.1
1.1
—
—
—
0
0
37
433
0.85
0.40
1.3
1.2
—
—
—
0
0
11
149
0.74
0.40
1.1
1.1
—
—
—
0
0
232
2192
1.06
0.38
4.2
3.8
1.2
1.2
mmol/l
0.21
201
1905
12
89
1.35
0.37
9.0
14.3
—
—
—
0
0
23
188
1.22
0.37
1.3
1.3
0.5
1.4
u/ml
0.64
12
80
15
116
1.29
0.37
1.2
1.1
283.3
190.1
iu/ml
0.23
15
116
5
78
0.64
0.35
1.0
1.6
—
—
—
0
0
68
612
1.11
0.35
3.3
4.2
2.4
2.7
mmol/l
0.39
39
417
6
42
1.43
0.35
1.3
1.5
134.7
116.7
ng/l
—
6
42
66
593
1.12
0.35
2.1
2.2
130.7
129.3
g/l
0.14
43
430
19
153
1.24
0.35
1.4
1.2
—
—
—
0
0
68
613
1.11
0.34
3.3
4.2
4.9
5.0
kpa
0.68
63
607
6
44
1.36
0.34
1.2
1.4
9.3
760007.6
nmol/l
—
6
35
161
1714
0.94
0.34
1.4
1.4
—
—
—
0
0
6
45
1.33
0.33
4.3
3.1
—
—
—
0
0
221
2098
1.06
0.33
4.2
4.1
0.0
0.2
%
0.70
52
494
10
132
0.76
0.32
1.3
1.4
—
—
—
0
0
27
229
1.18
0.32
1.2
1.1
25.5
44.4
mg/l
3.88
22
191
17
137
1.24
0.32
1.9
2.6
1008.2
1097.6
u/ml
0.12
17
137
17
137
1.24
0.32
1.7
1.8
—
—
—
0
0
68
617
1.10
0.32
3.3
4.2
8.9
8.6
kpa
1.10
63
610
18
147
1.23
0.30
2.1
2.0
2.1
2.3
ug/l
0.23
13
127
7
55
1.27
0.30
1.7
2.2
19.9
18.0
umol/l
—
7
55
7
55
1.27
0.30
1.0
1.0
—
—
—
0
0
20
239
0.84
0.29
1.6
1.5
—
—
—
0
0
29
335
0.86
0.29
4.2
2.8
—
—
—
0
0
17
139
1.22
0.29
1.8
2.4
—
—
—
0
0
7
57
1.23
0.29
1.1
1.1
—
—
—
0
0
21
176
1.19
0.28
1.0
1.0
844.0
704.5
ng/l
0.50
11
117
72
660
1.09
0.28
1.9
2.1
—
—
—
0
0
67
612
1.10
0.28
1.1
1.2
—
—
—
0
0
29
334
0.87
0.28
1.6
1.5
33.6
32.4
g/l
0.22
24
302
13
103
1.26
0.28
1.1
1.2
—
0.1
g/l
—
0
9
11
140
0.79
0.28
1.4
1.3
—
—
—
0
0
12
94
1.28
0.28
1.7
1.7
—
—
—
0
0
8
63
1.27
0.27
1.4
1.4
—
—
—
0
0
35
396
0.88
0.27
1.1
1.1
4.0
4.0
u/ml
0.01
21
153
16
131
1.22
0.27
1.0
1.1
1585.6
1546.8
miu/ml
0.05
16
131
20
168
1.19
0.27
1.0
1.1
1.1
1.0
ratio
—
8
62
17
204
0.83
0.27
1.4
1.4
—
—
—
0
0
10
128
0.78
0.26
1.3
1.3
—
—
—
0
0
243
2331
1.05
0.26
4.1
4.1
0.7
0.8
%
0.61
63
641
5
71
0.70
0.26
8.4
5.7
—
—
—
0
0
5
71
0.70
0.26
4.2
2.9
—
—
—
0
0
16
132
1.21
0.25
2.1
1.7
—
—
—
0
0
26
226
1.15
0.24
1.4
1.4
1.4
1.3
promille
0.10
20
183
23
198
1.16
0.24
1.5
1.4
95.0
212.9
pmol/l
—
9
60
11
87
1.27
0.24
1.5
1.6
—
—
—
0
0
22
189
1.17
0.24
1.0
1.0
—
—
—
0
0
18
152
1.19
0.23
1.9
1.6
—
—
—
0
0
11
88
1.25
0.22
1.1
1.1
—
—
—
0
0
7
91
0.77
0.22
1.0
1.1
—
—
—
0
0
33
295
1.12
0.22
2.4
1.6
—
—
—
0
0
29
257
1.13
0.22
1.1
1.1
—
—
—
0
0
59
545
1.08
0.22
1.6
1.3
—
—
—
0
0
280
2710
1.04
0.21
3.8
4.1
8.2
29.3
ug/l
2.52
222
2187
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
49
1.22
0.20
1.8
1.5
—
—
—
0
0
78
733
1.07
0.19
3.2
3.9
7.4
7.4
ph
0.55
63
606
11
90
1.22
0.19
1.5
1.7
—
—
—
0
0
220
2127
1.04
0.19
3.4
3.9
0.5
0.5
%
0.06
40
463
16
137
1.17
0.18
1.4
1.6
1.9
3.1
u/field
—
10
102
19
217
0.87
0.18
1.5
1.5
0.8
1.0
g/l
2.03
19
217
7
58
1.21
0.18
1.4
1.3
—
—
—
0
0
294
2863
1.03
0.17
1.6
1.7
—
—
—
0
0
10
82
1.22
0.17
1.0
1.0
—
—
—
0
0
25
278
0.90
0.17
1.6
1.4
10679.1
60560.9
e6/l
1.73
14
170
45
485
0.93
0.17
1.1
1.1
0.8
2.5
u/ml
1.83
16
123
229
2224
1.03
0.16
4.2
4.1
0.1
0.1
%
0.43
55
598
20
177
1.13
0.16
1.0
1.0
221.4
298.9
ng/l
1.52
11
120
249
2424
1.03
0.15
1.4
1.4
—
—
—
0
0
51
477
1.07
0.15
3.0
3.2
—
—
—
0
0
6
80
0.75
0.15
1.2
1.9
—
—
—
0
0
44
472
0.93
0.15
2.9
3.1
0.8
0.8
nmol/l
0.14
35
363
18
159
1.13
0.15
1.8
1.4
1.8
1.2
nmol/l
—
9
130
7
86
0.81
0.14
3.7
7.2
25.1
24.8
mmol/l
—
7
78
13
112
1.16
0.14
2.5
1.6
—
—
—
0
0
23
208
1.11
0.14
2.0
2.0
2.7
1.9
u/field
—
10
84
62
587
1.06
0.14
1.1
1.1
1.2
1.8
u/ml
0.29
29
251
35
324
1.08
0.14
1.6
1.5
—
—
—
0
0
35
324
1.08
0.14
1.6
1.5
—
—
—
0
0
35
324
1.08
0.14
1.6
1.5
—
—
—
0
0
35
324
1.08
0.14
1.6
1.5
—
—
—
0
0
32
295
1.09
0.14
1.6
1.3
—
—
—
0
0
54
571
0.94
0.13
2.2
2.1
0.9
0.8
nmol/l
0.35
47
478
10
85
1.18
0.12
1.1
1.1
—
—
—
0
0
54
569
0.95
0.12
2.3
2.4
16.7
16.3
%
0.26
24
295
45
477
0.94
0.12
1.1
1.1
71.0
1230.2
iu/ml
—
6
110
64
611
1.05
0.11
2.5
2.4
135.2
108.2
ug/min
0.17
38
384
13
115
1.13
0.10
1.1
1.2
—
—
—
0
0
52
495
1.05
0.10
2.7
2.9
—
—
—
0
0
65
677
0.96
0.10
4.2
3.4
24.9
25.1
mmol/l
0.15
55
594
12
106
1.13
0.09
1.1
1.0
—
—
—
0
0
291
2863
1.02
0.09
1.4
1.4
—
—
—
0
0
29
309
0.94
0.09
1.6
1.4
4441.6
2267.0
e6/l
0.37
23
224
25
268
0.93
0.09
1.6
1.4
—
—
—
0
0
61
634
0.96
0.08
1.3
1.3
—
—
—
0
0
51
489
1.04
0.08
1.4
1.6
—
—
—
0
0
24
224
1.07
0.08
1.3
1.2
—
—
—
0
0
42
440
0.95
0.08
3.0
1.4
75.1
63.2
mmol/l
0.72
31
348
13
117
1.11
0.08
1.8
1.6
—
—
—
0
0
7
67
1.04
0.08
1.0
1.0
—
—
—
0
0
7
67
1.04
0.08
1.0
1.0
—
—
—
0
0
7
67
1.04
0.08
1.0
1.0
—
—
—
0
0
26
276
0.94
0.07
2.8
2.7
—
—
—
0
0
111
1135
0.98
0.07
1.0
1.1
—
—
—
0
0
25
265
0.94
0.07
4.5
3.7
64.7
43.3
u/ml
0.27
25
265
8
92
0.87
0.06
1.0
1.0
—
—
—
0
0
25
263
0.95
0.05
5.3
4.3
151.5
101.2
u/ml
—
7
66
60
616
0.97
0.05
3.5
3.6
—
—
—
0
0
73
715
1.02
0.04
1.1
1.1
—
—
—
0
0
15
160
0.94
0.04
8.3
6.3
—
—
—
0
0
37
358
1.03
0.04
1.1
1.1
1.9
4.4
u/ml
1.53
25
154
10
109
0.92
0.04
3.3
2.7
—
—
—
0
0
44
428
1.03
0.03
3.6
3.6
2.7
1.3
%
0.77
38
328
48
468
1.03
0.03
1.0
1.1
—
—
—
0
0
73
717
1.02
0.03
4.5
3.9
8.6
8.5
kpa
0.23
67
670
26
251
1.04
0.02
1.7
1.2
—
—
—
0
0
97
959
1.01
0.02
3.3
3.4
104.2
5355.2
u/ml
1.09
80
812
18
173
1.04
0.01
1.1
1.1
7.3
5.6
nmol/l
—
5
33
21
203
1.03
0.01
2.9
2.3
611.9
654.2
ml
0.27
15
141
13
128
1.02
0.00
1.8
1.5
—
—
—
0
0
13
135
0.96
0.00
1.1
1.2
—
—
—
0
0
47
468
1.00
0.00
1.0
1.1
—
—
—
0
0
53
525
1.01
0.00
1.1
1.1
4.8
5.5
u/ml
0.20
32
283
18
181
0.99
0.00
1.1
1.0
—
—
—
0
0
54
541
1.00
0.00
2.8
3.5
1537.7
821.4
u/ml
0.19
49
504
51
507
1.01
0.00
1.1
1.1
0.2
1.5
u/ml
2.60
22
230
7
69
1.01
0.00
1.3
1.5
14.4
13.0
g/l
—
7
50
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
0.00
1.2
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
5
55
0.91
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
1642.8
—
0
6
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
6
59
1.02
0.00
10.2
8.4
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
125.3
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
268.0
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
5
54
0.93
0.00
2.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
0.00
5.6
4.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_HL_CON_NAS and mortality.

Females

Parameter HR [95% CI] p-value
H8_HL_CON_NAS 0.969 [0.88, 1.07] 0.529
Birth year 0.997 [0.99, 1.01] 0.503

During the follow-up period (1.1.1998 — 31.12.2019), 1734 out of 14162 females with H8_HL_CON_NAS died.

Males

Parameter HR [95% CI] p-value
H8_HL_CON_NAS 0.964 [0.86, 1.07] 0.505
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1735 out of 12076 males with H8_HL_CON_NAS died.

Mortality risk

Mortality risk for people of age

years, who have H8_HL_CON_NAS.

N-year risk Females Males
1 0.099% 0.181%
5 0.629% 0.973%
10 1.507% 2.45%
15 2.841% 4.827%
20 5.133% 8.084%

Relationships between endpoints

Index endpoint: H8_HL_CON_NAS – Conductive hearing loss, unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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