No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
342 |
4. Check minimum number of eventsNone |
342 |
5. Include endpointsNone |
342 |
6. Filter based on genotype QC (FinnGen only) |
328 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF6
- Parent code in ICD-10
- H70
- Name in latin
- Mastoiditis acuta
Similar endpoints
↥List of similar endpoints to
Acute mastoiditis
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3448 | 1399 | 2033 |
| Only index persons | 3116 | 1283 | 1833 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.04 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 20.70 | 22.79 | 19.10 |
| Only index persons | 20.06 | 21.89 | 18.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 328 | 172 | 156 |
| Unadjusted period prevalence (%) | 0.07 | 0.06 | 0.07 |
| Median age at first event (years) | 25.24 | 29.62 | 20.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 342
- Matched controls
- 3420
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H70.0
ICD-10 Finland
Acute mastoiditis
+∞
189.8
164
*
38200
ICD-8 Finland
Acute / Acute otitis media with mastoiditis
+∞
145.5
129
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
14.7
95.8
98
91
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
349.0
59.3
58
*
DFF00
NOMESCO Finland
Pure tone audiometry
7.2
43.9
75
129
DC1AD
NOMESCO Finland
Temporalbone CT
146.2
37.6
39
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
30.7
29
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
169.9
30.2
31
*
H66.9
ICD-10 Finland
Otitis media, unspecified
7.0
28.2
46
74
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
+∞
27.5
26
*
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
36.3
26.1
33
10
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
25.3
24
*
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
24.3
23
*
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
23.2
22
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
4.9
22.7
55
128
UDC00
NOMESCO Finland
Ear microscopy
5.3
22.3
49
105
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.0
21.5
70
205
38300
ICD-8 Finland
Mastoiditis without mention of otitis media, Acute
+∞
20.0
19
*
DEB00
NOMESCO Finland
Cortical mastoidectomy
+∞
20.0
19
*
H02AB04
ATC
methylprednisolone; systemic
3.4
17.7
74
255
H70.9
ICD-10 Finland
Mastoiditis, unspecified
+∞
16.8
16
*
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
167.3
15.6
16
*
DC1BD
NOMESCO Finland
Temporal bone extensive CT
+∞
14.7
14
*
3830A
ICD-9 Finland
Mastoiditis and related conditions, Acute mastoiditis
+∞
14.7
14
*
H65.0
ICD-10 Finland
Acute serous otitis media
21.1
13.9
20
10
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
13.6
13
*
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
12.6
12
*
H92.0
ICD-10 Finland
Otalgia
4.1
12.5
36
95
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
12.3
210
1402
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
11.6
103
520
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
11.5
11
*
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
11.5
11
*
DCD00
NOMESCO Finland
Myringoplasty
+∞
11.5
11
*
H65.2
ICD-10 Finland
Chronic serous otitis media
+∞
11.5
11
*
J01MA02
ATC
ciprofloxacin; systemic
2.2
11.0
140
818
H60.3
ICD-10 Finland
Other infective otitis externa
8.6
10.5
22
27
4122
FHL
Tympanostomy (tympanic tube)
102.8
9.5
10
*
DEB30
NOMESCO Finland
Radical mastoidectomy
102.8
9.5
10
*
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
31.0
9.5
12
*
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
22.4
9.4
13
6
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
9.4
9
*
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
9.4
9
*
J01FF01
ATC
clindamycin; systemic
2.2
9.2
103
566
J01DC02
ATC
cefuroxime; systemic
3.5
9.2
33
102
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
16.1
9.1
14
9
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
2.8
9.0
48
187
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
19.2
9.0
13
7
TDA90
NOMESCO Finland
Removal wax from ear
11.1
8.9
16
15
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
8.7
148
947
38204, ,
ICD-8 Finland
+∞
8.4
8
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
8.4
8
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
8.1
51
217
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.1
8.0
22
56
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.6
7.8
50
214
G51.0
ICD-10 Finland
Bell palsy
6.7
7.5
18
28
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
7.3
7
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
7.3
7
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
7.3
121
757
N02AX02
ATC
tramadol; systemic, rectal
1.9
7.2
146
975
H02AB06
ATC
prednisolone; systemic
1.9
7.2
164
1136
AA1AD
NOMESCO Finland
CT of head and brain
2.0
7.2
87
488
S02CA02
ATC
flumetasone and antiinfectives; otic
3.6
7.1
24
71
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
14.2
6.9
11
8
D07AB08
ATC
desonide; topical
2.5
6.8
44
189
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
6.8
52
242
H01
ICPC
Ear pain/earache
2.4
6.7
49
223
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.2
6.7
18
45
H60.8
ICD-10 Finland
Other otitis externa
4.1
6.5
18
46
J01MA12
ATC
levofloxacin; systemic
2.1
6.5
65
338
J01DB01
ATC
cefalexin; oral
2.2
6.4
288
2435
DCD10
NOMESCO Finland
Tympanoplasty
+∞
6.3
6
*
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
+∞
6.3
6
*
38202, ,
ICD-8 Finland
+∞
6.3
6
*
ZXD05
NOMESCO Finland
Urgent procedure
1.8
6.3
113
721
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
6.2
93
558
H66
ICD-10 Finland
Suppurative and unspecified otitis media
5.9
6.2
16
28
WX402
NOMESCO Finland
General anaesthesia
2.0
6.1
75
420
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
12.8
6.1
10
8
ZXA05
NOMESCO Finland
Left side
2.0
6.1
76
429
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
20
40
5.25
9.69
1.6
1.4
—
—
—
0
0
24
72
3.51
6.97
2.0
2.6
—
—
—
0
0
17
53
3.32
4.68
1.2
1.7
7244.08
139.09
e6/l
0.47
12
46
17
53
3.32
4.68
1.2
1.6
221.50
7.86
e6/l
0.47
12
42
62
362
1.87
4.42
2.6
1.7
—
—
—
0
0
149
1146
1.53
3.62
12.6
6.6
1.21
1.22
mmol/l
0.13
128
990
35
181
2.04
3.54
2.0
1.5
—
—
—
0
0
7
10
7.12
3.38
1.3
1.5
—
—
—
0
0
13
38
3.51
3.35
1.2
1.1
—
—
—
0
0
13
38
3.51
3.35
1.2
1.1
—
—
—
0
0
83
569
1.61
3.30
2.7
2.1
3.25
3.01
mg/l
0.21
71
494
26
123
2.21
3.29
2.8
1.4
—
—
—
0
0
39
217
1.90
3.22
2.1
2.3
—
13.31
—
0
17
141
1094
1.49
3.19
20.4
11.0
1.14
1.17
inr
0.20
44
342
56
350
1.72
3.17
1.8
1.7
988.74
1291.15
nmol/l
1.73
47
281
7
12
5.93
3.03
1.0
1.2
—
—
—
0
0
35
192
1.92
3.02
11.8
9.2
119.06
122.13
g/l
0.40
35
186
41
238
1.82
2.98
3.7
3.2
—
—
—
0
0
83
584
1.56
2.93
3.9
2.1
—
—
—
0
0
35
194
1.90
2.93
1.1
1.2
—
33.99
—
0
16
81
571
1.55
2.83
1.9
1.8
0.70
1.17
mg/l
1.74
63
440
289
2629
1.64
2.80
16.0
10.7
86.17
87.34
ml/min/173m2
0.38
247
2152
238
2079
1.48
2.76
3.7
3.3
—
—
—
0
0
99
734
1.49
2.73
2.6
2.1
206.25
200.21
u/l
0.04
91
701
39
231
1.78
2.66
10.6
8.4
1.47
1.24
mmol/l
0.19
32
184
42
255
1.74
2.64
2.9
1.6
—
—
—
0
0
33
187
1.85
2.60
17.8
8.4
8.62
8.36
mmol/l
0.09
33
180
16
68
2.42
2.60
1.5
1.4
—
—
—
0
0
10
31
3.29
2.54
1.1
1.7
—
—
—
0
0
42
261
1.69
2.44
2.9
1.6
—
—
—
0
0
11
38
2.96
2.43
1.7
1.4
—
—
—
0
0
126
997
1.42
2.43
8.1
5.0
35.40
36.42
g/l
1.17
116
947
38
230
1.73
2.42
11.4
8.3
5.23
5.10
kpa
0.29
38
220
38
230
1.73
2.42
11.4
8.3
13.62
12.41
kpa
0.53
38
222
9
27
3.39
2.41
1.1
1.8
—
—
—
0
0
148
1206
1.40
2.41
3.8
2.4
—
—
—
0
0
133
1064
1.41
2.41
2.4
2.3
75.20
74.16
nmol/l
0.15
118
971
89
663
1.46
2.37
4.1
2.6
0.59
0.51
e6/l
0.08
66
489
11
39
2.88
2.36
1.7
1.4
—
—
—
0
0
11
39
2.88
2.36
1.7
1.4
—
—
—
0
0
11
39
2.88
2.36
1.7
1.4
—
—
—
0
0
11
39
2.88
2.36
1.7
1.4
—
—
—
0
0
18
85
2.18
2.33
1.9
2.0
—
—
—
0
0
26
142
1.90
2.30
4.8
3.2
0.73
1.49
mmol/l
0.49
21
103
190
1623
1.38
2.29
5.7
3.8
—
120.93
—
0
27
116
913
1.41
2.28
2.3
1.8
98.42
96.49
pmol/l
0.12
63
484
15
67
2.30
2.21
3.3
1.5
—
—
—
0
0
82
609
1.46
2.21
1.9
1.6
—
—
—
0
0
43
277
1.63
2.19
9.2
6.8
104.70
103.84
mmol/l
0.52
43
277
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
14
4.34
2.16
1.0
1.3
—
—
—
0
0
111
877
1.39
2.11
4.9
2.7
—
—
—
0
0
54
375
1.52
2.01
3.7
2.3
1.30
2.74
e6/l
1.38
26
190
116
931
1.37
1.99
3.6
3.4
30.28
33.75
u/l
0.71
111
889
78
585
1.43
1.99
3.4
3.3
1154.48
961.59
ng/l
0.16
72
490
10
39
2.61
1.95
1.8
1.4
—
—
—
0
0
9
33
2.77
1.94
1.0
1.2
—
—
—
0
0
43
286
1.58
1.94
4.6
3.8
32.24
30.85
%
0.32
37
197
16
78
2.10
1.94
1.8
1.8
—
—
—
0
0
230
2056
1.36
1.93
3.8
3.9
14.53
14.52
pmol/l
0.01
214
1902
156
1317
1.34
1.92
9.4
6.0
57.64
57.22
%
0.19
151
1256
114
919
1.36
1.89
4.6
3.4
50.66
36.56
ng/l
0.20
73
591
157
1330
1.33
1.87
9.5
6.2
27.80
28.13
%
0.15
152
1269
11
46
2.44
1.87
1.8
1.6
—
—
—
0
0
6
17
3.57
1.84
1.3
1.4
3.95
1.87
mmol/l
—
6
17
5
12
4.21
1.83
1.2
1.8
—
—
—
0
0
5
12
4.21
1.83
1.2
1.8
—
—
—
0
0
5
12
4.21
1.83
1.2
1.8
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
60
2.21
1.80
3.2
4.0
0.27
0.33
u/ml
—
8
31
297
2785
1.50
1.79
22.6
13.0
139.44
139.64
mmol/l
0.77
289
2715
63
463
1.44
1.79
6.0
3.2
239.90
406.69
ng/l
0.28
45
329
9
36
2.54
1.75
1.3
1.1
—
—
—
0
0
298
2800
1.50
1.74
20.9
11.9
21.75
21.35
mg/l
0.09
250
2184
11
48
2.33
1.72
1.5
1.6
—
—
—
0
0
45
312
1.51
1.70
4.2
2.2
24.08
24.71
%
0.11
39
271
24
143
1.73
1.66
2.2
1.3
—
—
—
0
0
10
41
2.48
1.65
1.5
1.6
—
—
—
0
0
10
41
2.48
1.65
1.5
1.6
—
—
—
0
0
67
507
1.40
1.62
1.7
1.4
19.18
21.46
nmol/l
0.87
62
432
5
14
3.61
1.62
1.0
1.0
—
—
—
0
0
13
63
2.11
1.62
1.4
1.6
—
—
—
0
0
15
77
1.99
1.62
2.3
2.4
—
—
—
0
0
8
32
2.54
1.60
1.0
1.2
—
—
—
0
0
7
26
2.73
1.59
1.1
1.0
—
—
—
0
0
6
20
3.03
1.59
3.5
2.2
—
—
—
0
0
13
64
2.07
1.56
1.4
1.6
—
—
—
0
0
55
405
1.43
1.55
3.7
2.2
1.33
1.28
e6/l
0.03
28
219
297
2803
1.45
1.54
23.0
13.1
3.98
3.96
mmol/l
0.62
289
2728
5
15
3.37
1.53
1.4
1.7
—
—
—
0
0
5
15
3.37
1.53
1.0
3.7
—
—
—
0
0
5
15
3.37
1.53
1.2
1.7
—
—
—
0
0
5
15
3.37
1.53
1.2
1.7
—
—
—
0
0
54
398
1.42
1.52
2.7
2.7
2.46
2.43
mmol/l
0.86
43
348
6
21
2.89
1.51
1.2
1.7
—
—
—
0
0
6
21
2.89
1.51
1.2
1.7
—
—
—
0
0
6
21
2.89
1.51
1.2
1.7
—
—
—
0
0
9
38
2.40
1.46
1.2
1.6
—
—
—
0
0
6
22
2.76
1.44
1.2
1.6
75.50
78.00
umol/l
—
6
22
7
29
2.44
1.40
1.0
1.1
—
—
—
0
0
17
97
1.79
1.37
1.4
1.6
—
—
—
0
0
97
798
1.30
1.36
3.8
3.2
2.35
2.35
mmol/l
0.01
87
732
226
2064
1.28
1.35
3.3
3.3
47.84
46.37
u/l
0.10
214
1973
84
679
1.31
1.34
3.6
2.6
7790.54
4822.45
umol/l
0.20
74
608
6
24
2.53
1.31
1.0
1.3
—
—
—
0
0
6
24
2.53
1.31
1.0
1.3
—
—
—
0
0
149
1300
1.26
1.30
3.5
3.1
0.00
0.00
estimate
0.50
38
259
6
25
2.42
1.25
1.0
1.3
—
—
—
0
0
6
25
2.42
1.25
1.0
1.3
—
—
—
0
0
6
25
2.42
1.25
1.0
1.3
—
—
—
0
0
8
38
2.13
1.19
1.0
1.5
—
—
—
0
0
49
372
1.37
1.18
1.8
1.7
—
—
—
0
0
139
1214
1.24
1.17
4.1
2.7
120.15
114.37
ug/l
0.11
125
1143
266
2502
1.28
1.13
4.8
4.5
2.01
1.81
mu/l
0.53
247
2335
10
51
1.99
1.12
1.2
1.5
—
—
—
0
0
153
1358
1.23
1.10
7.4
6.5
9.96
10.99
umol/l
0.98
145
1303
216
1993
1.23
1.04
5.0
3.7
10.30
9.83
mm/h
0.24
205
1874
14
83
1.72
1.03
1.1
1.4
—
—
—
0
0
7
35
2.02
1.00
5.7
4.6
453.71
328.92
umol/l
—
7
26
20
132
1.55
0.99
16.3
6.7
24.03
24.75
mmol/l
0.57
20
125
9
49
1.86
0.99
1.3
1.2
—
—
—
0
0
146
1304
1.21
0.96
5.0
4.2
0.00
0.00
estimate
0.50
37
248
11
62
1.80
0.95
1.5
1.3
—
—
—
0
0
6
28
2.16
0.92
1.0
1.0
—
—
—
0
0
33
247
1.37
0.89
4.1
2.4
32.00
33.42
u/l
0.05
27
211
8
42
1.93
0.89
1.0
1.6
—
—
—
0
0
146
1315
1.19
0.85
3.5
3.1
0.00
0.00
estimate
-0.00
35
232
8
46
1.76
0.83
2.5
1.3
—
—
—
0
0
172
1578
1.18
0.80
11.9
9.7
4.33
4.04
e9/l
0.94
150
1396
5
97
0.51
0.79
1.2
1.4
—
—
—
0
0
97
847
1.20
0.79
4.1
2.6
53.71
55.31
u/l
0.19
91
798
217
2037
1.18
0.75
10.1
7.4
79.92
75.31
u/l
0.64
205
1928
9
56
1.62
0.73
1.4
1.9
—
—
—
0
0
55
458
1.24
0.71
1.6
1.7
470.63
20698689.68
pmol/l
0.50
46
401
5
26
1.94
0.71
1.8
1.6
—
—
—
0
0
5
26
1.94
0.71
1.8
1.6
—
—
—
0
0
308
2993
1.29
0.70
12.4
9.6
28.10
28.27
u/l
0.05
300
2924
57
478
1.23
0.70
1.5
1.2
13.73
29.16
iu/ml
2.41
19
170
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
5
28
1.80
0.66
1.0
1.1
—
—
—
0
0
5
28
1.80
0.66
1.8
1.3
—
—
—
0
0
79
691
1.19
0.63
3.4
3.3
0.00
0.02
estimate
0.68
35
240
324
3180
1.36
0.57
27.4
17.5
40.60
41.03
%
0.60
313
3025
17
124
1.39
0.57
1.6
1.7
—
—
—
0
0
324
3184
1.33
0.52
27.4
17.5
4.55
4.58
e12/l
0.49
316
3107
58
504
1.18
0.51
2.2
2.5
0.76
0.71
ug/l
0.18
26
275
92
832
1.14
0.49
3.6
3.8
1.43
1.81
ug/l
1.24
82
763
53
460
1.18
0.48
1.4
1.3
29.86
9.89
u/ml
0.62
20
190
17
130
1.32
0.45
3.2
2.4
2144.11
4122.98
u/l
—
9
42
74
664
1.15
0.44
1.2
1.3
1.00
1.05
u/ml
0.05
22
180
13
95
1.38
0.44
16.8
4.8
2.03
1.57
%
0.55
13
88
7
51
1.38
0.44
1.9
1.6
—
—
—
0
0
5
31
1.62
0.43
1.8
1.6
—
—
—
0
0
323
3181
1.28
0.43
27.6
17.5
252.79
253.09
e9/l
0.03
317
3110
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
74
668
1.14
0.41
2.8
3.5
20.01
21.64
%
0.32
22
262
0
18
0.00
0.40
0.0
1.0
—
651.87
—
0
8
0
18
0.00
0.40
0.0
1.0
—
43.50
—
0
8
5
35
1.43
0.39
1.4
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
9.1
—
38.13
—
0
8
39
448
0.85
0.38
1.3
1.8
1.25
1.45
%
1.43
31
404
10
72
1.40
0.37
1.3
1.3
—
—
—
0
0
5
37
1.36
0.37
1.8
1.5
—
—
—
0
0
6
42
1.44
0.35
1.2
1.1
—
—
—
0
0
276
2702
1.11
0.30
4.0
3.6
1.39
1.32
mmol/l
0.95
263
2538
7
56
1.26
0.29
1.1
1.2
—
—
—
0
0
111
1046
1.09
0.29
3.4
3.1
—
—
—
0
0
14
112
1.26
0.28
6.1
2.5
1.04
1.32
%
0.56
14
112
14
112
1.26
0.28
1.2
1.4
91.14
263.16
miu/ml
—
7
55
41
454
0.89
0.25
2.5
2.1
—
—
—
0
0
50
456
1.11
0.25
1.3
1.5
—
—
—
0
0
13
159
0.81
0.25
1.8
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
231.14
—
0
11
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
13
108
1.21
0.20
6.5
2.6
0.65
0.69
%
0.15
13
108
16
184
0.86
0.17
1.8
2.0
—
—
—
0
0
8
69
1.16
0.16
2.0
1.5
—
—
—
0
0
62
586
1.07
0.16
3.5
3.4
1.02
1.02
kg/l
0.01
19
66
21
234
0.89
0.15
2.0
2.0
—
—
—
0
0
9
83
1.09
0.14
1.1
1.1
—
—
—
0
0
22
199
1.11
0.13
2.9
2.4
71.00
69.20
ml/min/173m2
—
10
86
5
46
1.09
0.09
2.0
4.0
57.00
56.80
%
—
5
46
10
87
1.15
0.09
1.4
1.2
—
—
—
0
0
10
87
1.15
0.09
1.4
1.2
—
—
—
0
0
11
97
1.14
0.09
2.0
1.7
—
—
—
0
0
6
55
1.09
0.09
1.0
1.1
—
—
—
0
0
73
707
1.04
0.08
1.6
1.7
1.42
1.44
mmol/l
0.06
65
616
7
66
1.06
0.08
1.9
1.2
—
—
—
0
0
70
680
1.04
0.07
5.2
3.8
11.31
12.27
mg/mmol
0.07
39
448
9
86
1.05
0.07
1.3
1.2
—
—
—
0
0
8
93
0.86
0.07
1.4
1.4
—
—
—
0
0
8
93
0.86
0.07
1.4
1.4
—
—
—
0
0
8
93
0.86
0.07
1.4
1.4
—
—
—
0
0
40
416
0.96
0.06
2.3
2.0
—
—
—
0
0
26
274
0.94
0.06
5.9
6.7
—
—
—
0
0
280
2785
1.03
0.05
4.4
3.9
1.41
1.44
mmol/l
0.56
266
2625
16
169
0.94
0.03
1.1
1.1
—
—
—
0
0
267
2659
1.02
0.02
4.7
3.9
5.91
5.86
mmol/l
0.22
250
2485
282
2829
0.98
0.02
4.8
4.3
2.82
2.85
mmol/l
0.25
270
2662
21
203
1.04
0.01
1.1
1.2
228.14
156.01
iu/ml
—
7
81
10
94
1.07
0.01
1.4
1.8
—
—
—
0
0
280
2794
1.01
0.00
4.5
4.0
4.69
4.75
mmol/l
0.40
269
2648
252
2521
1.00
0.00
5.7
4.9
39.85
39.22
mmol/mol
0.41
237
2388
13
133
0.98
0.00
1.3
2.6
0.11
0.11
e6/l
0.01
13
126
17
167
1.02
0.00
1.4
1.3
—
—
—
0
0
7
69
1.01
0.00
1.1
1.2
—
8.49
—
0
14
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
9
95
0.95
-0.00
1.6
1.5
—
—
—
0
0
5
56
0.89
-0.00
1.2
1.3
—
51.20
—
0
6
5
56
0.89
-0.00
1.0
1.4
0.29
0.41
nmol/l
—
5
47
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
35.52
—
0
5
5
54
0.92
-0.00
2.0
1.4
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
98
0.92
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_MASTACU and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MASTACU | 1.511 [1.14, 2.01] | 0.004 |
| Birth year | 0.996 [0.99, 1.0] | 0.347 |
During the follow-up period (1.1.1998 — 31.12.2019), 63 out of 695 females with H8_MASTACU died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MASTACU | 1.681 [1.23, 2.29] | 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 95 out of 630 males with H8_MASTACU died.
Mortality risk
Mortality risk for people of age
years, who have H8_MASTACU.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.155% | 0.291% |
| 5 | 0.85% | 1.9% |
| 10 | 2.049% | 4.692% |
| 15 | 4.027% | 8.837% |
| 20 | 7.316% | 14.976% |
Relationships between endpoints
↥Index endpoint: H8_MASTACU – Acute mastoiditis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data