No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
334 |
4. Check minimum number of eventsNone |
334 |
5. Include endpointsNone |
334 |
6. Filter based on genotype QC (FinnGen only) |
334 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF6
- Parent code in ICD-10
- H70
- Name in latin
- Mastoiditis acuta
Similar endpoints
↥List of similar endpoints to
Acute mastoiditis
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3448 | 1399 | 2033 |
| Only index persons | 3116 | 1283 | 1833 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.04 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 20.70 | 22.79 | 19.10 |
| Only index persons | 20.06 | 21.89 | 18.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 334 | 174 | 160 |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | 0.07 |
| Median age at first event (years) | 25.32 | 29.84 | 20.40 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 307
- Matched controls
- 3069
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H70.0
ICD-10 Finland
Acute mastoiditis
866.0
159.2
143
*
38200
ICD-8 Finland
Acute / Acute otitis media with mastoiditis
+∞
138.3
122
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
20.7
53.6
82
53
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
590.9
52.1
50
*
DC1AD
NOMESCO Finland
Temporalbone CT
118.6
30.3
32
*
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
171.7
30.2
31
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
29.7
28
*
DFF00
NOMESCO Finland
Pure tone audiometry
8.7
27.3
62
87
H65.3
ICD-10 Finland
Chronic mucoid otitis media
76.6
25.2
28
*
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
259.3
24.0
24
*
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
23.2
22
*
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
22.1
21
*
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
21.1
20
*
H66.9
ICD-10 Finland
Otitis media, unspecified
8.9
19.8
43
55
38300
ICD-8 Finland
Mastoiditis without mention of otitis media, Acute
+∞
17.9
17
*
DEB00
NOMESCO Finland
Cortical mastoidectomy
+∞
16.8
16
*
UDC00
NOMESCO Finland
Ear microscopy
6.0
15.8
45
86
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
+∞
15.8
15
*
H65.0
ICD-10 Finland
Acute serous otitis media
89.7
15.7
17
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.6
14.7
182
1098
H60.9
ICD-10 Finland
Otitis externa, unspecified
5.0
13.1
43
97
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
12.6
12
*
3830A
ICD-9 Finland
Mastoiditis and related conditions, Acute mastoiditis
+∞
12.6
12
*
DC1BD
NOMESCO Finland
Temporal bone extensive CT
135.3
12.5
13
*
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
11.5
11
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.4
11.0
56
188
DCD00
NOMESCO Finland
Myringoplasty
+∞
10.5
10
*
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
10.5
10
*
4122
FHL
Tympanostomy (tympanic tube)
+∞
10.5
10
*
DEB30
NOMESCO Finland
Radical mastoidectomy
+∞
10.5
10
*
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
10.5
10
*
TDA90
NOMESCO Finland
Removal wax from ear
19.6
10.4
15
8
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
9.4
9
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
28.4
8.5
11
*
H70.9
ICD-10 Finland
Mastoiditis, unspecified
92.5
8.5
9
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
8.4
8
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
8.4
8
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.8
8.2
22
40
J01MA02
ATC
ciprofloxacin; systemic
2.1
8.2
118
700
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.4
8.1
74
353
H02AB04
ATC
methylprednisolone; systemic
2.6
8.0
59
253
H60.3
ICD-10 Finland
Other infective otitis externa
7.8
7.8
17
23
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
7.6
122
750
J01FF01
ATC
clindamycin; systemic
2.2
7.4
89
483
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
7.3
7
*
38204
ICD-8 Finland
NA
+∞
7.3
7
*
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
20.6
7.2
10
5
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
7.1
89
490
J01DB01
ATC
cefalexin; oral
2.2
7.1
253
2091
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
14.2
6.9
11
8
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
17.1
6.8
10
6
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
2.7
6.7
45
181
G51.0
ICD-10 Finland
Bell palsy
5.7
6.4
17
31
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
9.5
6.3
12
13
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
6.3
6
*
DCD10
NOMESCO Finland
Tympanoplasty
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
19
40
4.98
8.70
1.7
1.3
—
—
—
0
0
23
72
3.36
6.27
2.0
2.6
—
—
—
0
0
138
1005
1.64
4.50
9.6
6.0
1.2
1.2
mmol/l
0.02
133
933
15
51
3.03
3.62
1.2
1.6
265.2
7.6
e6/l
—
10
40
15
51
3.03
3.62
1.2
1.7
8690.7
131.4
e6/l
—
10
44
56
343
1.76
3.41
1.8
1.7
988.7
1291.8
nmol/l
1.73
47
275
7
10
7.12
3.38
1.3
1.5
—
—
—
0
0
58
360
1.74
3.37
2.6
1.7
—
—
—
0
0
144
1121
1.50
3.24
12.1
6.6
1.2
1.2
mmol/l
0.25
121
962
40
233
1.81
2.88
3.6
3.2
—
—
—
0
0
11
36
3.13
2.83
1.7
1.5
—
—
—
0
0
10
31
3.29
2.79
1.1
1.7
—
—
—
0
0
34
191
1.87
2.75
1.1
1.3
—
18.1
—
0
13
11
37
3.04
2.72
1.2
1.1
—
—
—
0
0
11
37
3.04
2.72
1.7
1.5
—
—
—
0
0
11
37
3.04
2.72
1.7
1.5
—
—
—
0
0
11
37
3.04
2.72
1.7
1.5
—
—
—
0
0
11
37
3.04
2.72
1.2
1.1
—
—
—
0
0
11
37
3.04
2.72
1.7
1.5
—
—
—
0
0
32
177
1.89
2.71
2.1
1.6
—
—
—
0
0
24
122
2.04
2.58
2.8
1.4
—
—
—
0
0
281
2564
1.60
2.57
15.5
10.7
85.9
87.3
ml/min/173m2
0.46
240
2094
6
11
5.53
2.55
1.0
1.3
—
—
—
0
0
15
63
2.45
2.50
3.3
1.5
—
—
—
0
0
77
553
1.51
2.47
2.8
2.2
3.3
3.0
mg/l
0.26
66
480
9
27
3.40
2.41
1.1
1.8
—
—
—
0
0
123
972
1.42
2.40
7.8
5.1
35.5
36.4
g/l
0.99
114
918
78
565
1.50
2.40
4.0
2.1
—
—
—
0
0
18
84
2.21
2.39
1.9
2.0
—
—
—
0
0
143
1169
1.39
2.27
5.4
3.9
—
—
—
0
0
230
2037
1.41
2.24
3.6
3.3
—
—
—
0
0
15
68
2.26
2.14
1.5
1.4
—
—
—
0
0
10
37
2.76
2.12
1.8
1.5
—
—
—
0
0
94
722
1.42
2.12
2.7
2.2
211.5
201.9
u/l
0.07
86
689
79
588
1.45
2.11
1.9
1.5
—
—
—
0
0
43
281
1.61
2.08
4.6
3.8
32.2
30.9
%
0.30
37
191
128
1039
1.38
2.08
2.5
2.3
75.2
74.4
nmol/l
0.11
115
947
16
77
2.13
2.00
1.8
1.8
—
—
—
0
0
30
180
1.73
2.00
19.4
8.5
8.8
8.3
mmol/l
0.14
30
173
36
228
1.65
1.97
9.2
8.3
1.3
1.3
mmol/l
0.03
28
180
31
189
1.71
1.95
9.9
7.6
1.2
1.4
mmol/l
1.01
31
184
9
33
2.77
1.94
1.0
1.2
—
—
—
0
0
75
563
1.43
1.91
1.9
1.8
0.7
1.2
mg/l
1.59
60
435
5
12
4.21
1.83
1.2
1.8
—
—
—
0
0
5
12
4.21
1.83
1.2
1.8
—
—
—
0
0
5
12
4.21
1.83
1.2
1.8
—
—
—
0
0
84
649
1.39
1.81
4.1
2.6
0.6
0.5
e6/l
0.10
62
473
52
367
1.49
1.81
3.7
2.3
1.3
2.7
e6/l
1.34
26
184
24
139
1.78
1.81
2.2
1.3
—
—
—
0
0
35
227
1.61
1.76
9.5
8.2
5.2
5.1
kpa
0.23
35
217
35
227
1.61
1.76
9.4
8.2
13.4
12.4
kpa
0.50
35
219
9
36
2.54
1.75
1.3
1.1
—
—
—
0
0
110
894
1.34
1.72
2.3
1.8
97.7
96.6
pmol/l
0.06
59
474
44
303
1.52
1.72
4.3
2.2
24.6
24.8
%
0.05
38
262
11
48
2.34
1.72
1.5
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
13
3.89
1.72
1.0
1.3
—
—
—
0
0
106
859
1.34
1.69
4.9
2.8
—
—
—
0
0
38
255
1.55
1.67
2.8
1.6
—
—
—
0
0
6
19
3.20
1.67
3.5
2.3
—
—
—
0
0
223
2012
1.33
1.64
3.7
3.9
14.5
14.5
pmol/l
0.05
207
1864
74
570
1.38
1.62
3.4
3.3
1207.5
937.2
ng/l
0.22
68
477
8
32
2.54
1.60
1.0
1.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
12
57
2.15
1.57
3.2
3.9
0.3
0.3
u/ml
—
7
29
290
2735
1.46
1.54
20.3
12.0
21.4
21.5
mg/l
0.02
243
2129
109
898
1.32
1.54
4.7
3.4
51.9
36.5
ng/l
0.21
71
574
5
15
3.37
1.53
1.2
1.7
—
—
—
0
0
5
15
3.37
1.53
1.2
1.7
—
—
—
0
0
5
15
3.37
1.53
1.2
1.7
—
—
—
0
0
5
15
3.37
1.53
1.2
1.7
—
—
—
0
0
7
27
2.63
1.52
1.1
1.0
—
—
—
0
0
38
261
1.51
1.52
2.9
1.7
—
—
—
0
0
6
21
2.89
1.51
1.2
1.7
—
—
—
0
0
6
21
2.89
1.51
1.2
1.7
—
—
—
0
0
6
21
2.89
1.51
1.2
1.7
—
—
—
0
0
289
2726
1.45
1.51
21.8
13.0
139.4
139.6
mmol/l
0.80
281
2659
50
364
1.44
1.50
1.7
1.7
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
—
—
—
0
0
5
16
3.16
1.44
1.4
1.4
4.5
1.8
mmol/l
—
5
16
10
46
2.21
1.41
1.9
1.6
—
—
—
0
0
53
397
1.40
1.37
3.8
2.2
1.3
1.3
e6/l
0.01
28
213
289
2743
1.40
1.28
22.1
13.1
4.0
4.0
mmol/l
0.51
281
2673
29
197
1.52
1.24
8.2
3.9
1.3
2.2
mmol/l
0.94
22
153
82
668
1.30
1.24
3.6
2.6
8108.3
5375.1
umol/l
0.17
71
594
220
2021
1.26
1.20
3.3
3.3
48.2
46.7
u/l
0.11
208
1932
12
64
1.91
1.19
1.4
1.6
—
—
—
0
0
8
38
2.13
1.19
1.3
1.6
—
—
—
0
0
16
95
1.72
1.16
1.4
1.6
—
—
—
0
0
12
65
1.88
1.15
1.4
1.6
—
—
—
0
0
143
1259
1.24
1.12
3.4
3.1
0.0
0.0
estimate
0.00
34
233
11
59
1.89
1.08
1.5
1.3
—
—
—
0
0
50
387
1.34
1.08
2.7
2.7
2.5
2.4
mmol/l
0.73
39
339
92
778
1.25
1.03
3.8
3.3
2.4
2.4
mmol/l
0.06
82
704
259
2443
1.27
1.03
4.6
4.5
2.0
1.8
mu/l
0.54
240
2280
13
76
1.74
1.00
2.5
2.4
—
—
—
0
0
9
50
1.82
0.97
1.3
1.2
—
—
—
0
0
61
495
1.28
0.95
1.7
1.4
19.1
21.6
nmol/l
0.92
56
422
9
52
1.75
0.93
1.2
1.5
—
—
—
0
0
56
453
1.28
0.90
5.9
3.2
178.9
410.5
ng/l
0.43
41
326
36
273
1.36
0.90
42.6
18.6
1.3
1.2
inr
—
5
43
141
1266
1.20
0.86
4.9
4.2
0.0
0.0
estimate
0.50
36
235
147
1330
1.19
0.82
7.3
6.4
10.0
10.9
umol/l
0.74
140
1275
19
131
1.48
0.80
11.9
6.7
24.0
24.9
mmol/l
0.68
19
122
5
98
0.50
0.79
1.2
1.4
—
—
—
0
0
78
668
1.22
0.78
3.3
3.4
0.0
0.0
estimate
0.68
34
229
131
1179
1.18
0.77
4.2
2.7
122.8
115.0
ug/l
0.15
118
1110
208
1946
1.18
0.76
5.0
3.8
10.2
9.8
mm/h
0.21
197
1829
141
1278
1.18
0.76
3.5
3.1
0.0
0.0
estimate
0.00
34
220
9
54
1.68
0.75
1.4
1.9
—
—
—
0
0
5
24
2.10
0.75
1.0
1.3
—
—
—
0
0
5
24
2.10
0.75
1.0
1.3
—
—
—
0
0
5
25
2.01
0.73
1.0
1.3
—
—
—
0
0
5
25
2.01
0.73
1.0
1.3
—
—
—
0
0
5
25
2.01
0.73
1.0
1.3
—
—
—
0
0
7
39
1.81
0.73
1.0
1.5
—
—
—
0
0
5
26
1.94
0.71
1.0
1.1
—
—
—
0
0
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
94
830
1.18
0.68
4.1
2.7
53.7
55.3
u/l
0.19
88
781
54
452
1.23
0.67
1.6
1.7
475.3
20960028.4
pmol/l
0.50
45
396
7
43
1.64
0.67
1.0
1.6
—
—
—
0
0
5
28
1.80
0.66
1.0
1.0
—
—
—
0
0
5
28
1.80
0.66
1.8
1.3
—
—
—
0
0
36
440
0.80
0.61
1.2
1.8
1.2
1.4
%
1.69
28
397
6
35
1.73
0.58
5.0
5.0
459.5
340.9
umol/l
—
6
26
6
35
1.73
0.58
1.5
1.4
—
—
—
0
0
12
82
1.48
0.55
1.2
1.4
—
—
—
0
0
30
242
1.26
0.53
4.0
2.4
33.2
33.5
u/l
0.01
25
206
57
493
1.19
0.53
2.2
2.5
0.8
0.7
ug/l
0.16
26
268
271
2623
1.18
0.53
18.7
12.4
40.4
41.0
%
0.50
225
2116
17
224
0.75
0.51
2.2
2.0
—
—
—
0
0
300
2932
1.23
0.50
12.1
9.6
28.3
28.4
u/l
0.02
292
2865
209
1992
1.13
0.49
10.1
7.4
80.4
75.4
u/l
0.69
199
1883
54
469
1.18
0.48
1.5
1.2
14.5
30.0
iu/ml
2.20
17
161
7
46
1.53
0.48
2.7
1.3
—
—
—
0
0
16
120
1.35
0.47
2.5
2.5
2408.0
3711.3
u/l
—
8
38
90
817
1.14
0.46
3.5
3.8
1.4
1.8
ug/l
1.19
80
748
5
31
1.62
0.43
1.8
1.6
—
—
—
0
0
10
139
0.71
0.43
1.9
1.4
—
—
—
0
0
72
648
1.14
0.42
1.2
1.3
1.0
1.0
u/ml
0.02
21
176
16
123
1.32
0.41
1.6
1.7
—
—
—
0
0
8
60
1.34
0.40
2.0
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
43.5
—
0
8
0
18
0.00
0.40
0.0
1.0
—
651.9
—
0
8
10
71
1.42
0.39
1.3
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
9.1
—
38.1
—
0
8
5
37
1.36
0.37
1.8
1.5
—
—
—
0
0
109
1016
1.11
0.36
3.3
3.1
—
—
—
0
0
38
435
0.86
0.36
2.4
2.1
—
—
—
0
0
163
1551
1.10
0.35
11.9
9.7
4.3
4.0
e9/l
0.87
142
1370
72
658
1.12
0.34
2.7
3.5
20.0
21.7
%
0.33
22
258
14
111
1.27
0.30
1.2
1.4
91.1
263.2
miu/ml
—
7
55
7
56
1.26
0.29
1.1
1.2
—
—
—
0
0
6
82
0.73
0.24
1.3
1.4
—
—
—
0
0
6
82
0.73
0.24
1.3
1.4
—
—
—
0
0
6
82
0.73
0.24
1.3
1.4
—
—
—
0
0
49
449
1.11
0.23
1.3
1.3
31.4
9.1
u/ml
0.68
19
184
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
12.7
—
0
10
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
269
2646
1.09
0.21
4.0
3.6
1.4
1.3
mmol/l
1.05
256
2483
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
6
49
1.23
0.20
2.0
1.6
—
—
—
0
0
22
194
1.14
0.19
3.0
2.4
71.0
69.2
ml/min/173m2
—
10
84
15
174
0.86
0.18
1.8
2.1
—
—
—
0
0
274
2772
0.94
0.15
4.8
4.3
2.8
2.9
mmol/l
0.28
262
2600
9
83
1.09
0.14
1.1
1.1
—
—
—
0
0
47
441
1.08
0.14
1.3
1.5
—
—
—
0
0
244
2473
0.95
0.13
5.7
4.9
40.0
39.2
mmol/mol
0.51
229
2341
67
700
0.95
0.12
1.6
1.7
1.4
1.4
mmol/l
0.05
59
609
38
400
0.94
0.09
2.2
2.0
—
—
—
0
0
10
88
1.14
0.08
1.4
1.2
—
—
—
0
0
10
88
1.14
0.08
1.4
1.2
—
—
—
0
0
7
65
1.08
0.08
1.9
1.2
—
—
—
0
0
7
84
0.83
0.07
1.4
1.5
—
—
—
0
0
9
86
1.05
0.07
1.3
1.2
—
—
—
0
0
68
661
1.04
0.07
5.6
4.0
11.3
10.4
mg/mmol
0.06
39
436
8
95
0.84
0.06
1.5
1.4
—
—
—
0
0
272
2738
0.96
0.06
4.4
4.0
4.7
4.7
mmol/l
0.48
261
2585
59
574
1.03
0.05
3.3
3.4
1.0
1.0
kg/l
0.01
17
65
12
110
1.09
0.05
7.0
2.6
0.9
1.3
%
0.88
12
110
26
270
0.96
0.03
5.9
6.4
—
—
—
0
0
12
128
0.94
0.02
1.4
1.8
176.6
318.2
mu/l
3.54
12
119
260
2610
0.98
0.02
4.6
3.9
5.9
5.9
mmol/l
0.28
243
2439
272
2727
0.99
0.01
4.3
4.0
1.4
1.4
mmol/l
0.61
258
2561
13
131
0.99
0.00
1.3
2.6
0.1
0.1
e6/l
0.01
13
124
16
161
0.99
0.00
1.1
1.1
—
—
—
0
0
17
166
1.03
0.00
1.4
1.3
—
—
—
0
0
5
56
0.89
0.00
1.2
1.3
—
51.2
—
0
6
7
69
1.01
0.00
1.1
1.2
—
8.5
—
0
14
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
0.00
1.6
1.7
—
—
—
0
0
5
53
0.94
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
9
94
0.96
0.00
1.7
1.9
—
—
—
0
0
20
200
1.00
0.00
1.1
1.2
263.3
157.9
iu/ml
—
6
80
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
35.5
—
0
5
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_MASTACU and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MASTACU | 1.511 [1.14, 2.01] | 0.004 |
| Birth year | 0.996 [0.99, 1.0] | 0.347 |
During the follow-up period (1.1.1998 — 31.12.2019), 63 out of 695 females with H8_MASTACU died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MASTACU | 1.681 [1.23, 2.29] | 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 95 out of 630 males with H8_MASTACU died.
Mortality risk
Mortality risk for people of age
years, who have H8_MASTACU.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.155% | 0.291% |
| 5 | 0.85% | 1.9% |
| 10 | 2.049% | 4.692% |
| 15 | 4.027% | 8.837% |
| 20 | 7.316% | 14.976% |
Relationships between endpoints
↥Index endpoint: H8_MASTACU – Acute mastoiditis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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