No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
207 |
4. Check minimum number of eventsNone |
207 |
5. Include endpointsNone |
207 |
6. Filter based on genotype QC (FinnGen only) |
203 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Idiopathic hypercalciuria
based on the number of shared cases.
Similar with more cases:
- Disorders of calcium metabolism
- Disorders of mineral metabolism
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 203 | 108 | 95 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 55.04 | 56.78 | 53.06 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 207
- Matched controls
- 2070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E83.58
ICD-10 Finland
Idiopathic hypercalciuria
+∞
299.7
207
*
N20.1
ICD-10 Finland
Calculus of ureter
28.4
79.7
58
28
N20.0
ICD-10 Finland
Calculus of kidney
33.5
69.9
47
18
N20.9
ICD-10 Finland
Urinary calculus, unspecified
32.6
65.1
44
17
KH1AD
NOMESCO Finland
CT of urinary organs
21.6
49.3
39
22
C03AA03
ATC
hydrochlorothiazide; oral
9.1
38.0
54
77
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
8.9
33.3
47
66
M05BA04
ATC
alendronic acid; oral
9.0
31.9
44
60
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
5.4
24.9
62
153
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
47.9
24.3
29
7
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
30.8
20.6
27
10
UKC02
NOMESCO Finland
Cystoscopy
4.7
20.0
57
155
E21.0
ICD-10 Finland
Primary hyperparathyroidism
21.4
16.0
23
12
E83.50
ICD-10 Finland
Hypercalcemia
29.7
14.6
19
7
KAE12
NOMESCO Finland
Retrograde ureteronephroscopic lithotripsy in pelvis of kidney
57.5
14.0
16
*
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
36.8
13.7
17
5
KH1AA
NOMESCO Finland
Urinary tract X-ray examination without contrast
18.9
12.8
19
11
M81.5
ICD-10 Finland
Idiopathic osteoporosis
74.6
12.8
14
*
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
26.3
12.7
17
7
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
19.6
12.3
18
10
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
24.6
11.8
16
7
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
24.6
11.8
16
7
N20.2
ICD-10 Finland
Calculus of kidney with calculus of ureter
29.8
10.9
14
5
M81.9
ICD-10 Finland
Osteoporosis, unspecified
10.0
10.8
21
23
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
10.1
88
457
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.6
10.0
25
60
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
18.6
9.5
14
8
R31
ICD-10 Finland
Unspecified haematuria
3.6
8.8
31
96
M80.5
ICD-10 Finland
Idiopathic osteoporosis with pathological fracture
52.2
8.8
10
*
M05BX04
ATC
denosumab; parenteral
4.5
8.7
22
53
N21.0
ICD-10 Finland
Calculus in bladder
19.3
7.7
11
6
KCE02
NOMESCO Finland
Transluminal endoscopic extraction of calculus from bladder
26.1
7.6
10
*
KBT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of ureter
26.1
7.6
10
*
KBV10
NOMESCO Finland
Removal of stent from ureter
31.2
7.2
9
*
M81.8
ICD-10 Finland
Other osteoporosis
20.9
7.2
10
5
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
9.3
7.2
14
16
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
9.3
7.2
14
16
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
7.1
85
491
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
6.9
57
281
E83.59
ICD-10 Finland
Other disorders of calcium metabolism
72.0
6.5
7
*
M821, E8358,
ICD-10 Finland
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
131
36
97.39
227.39
4.6
1.7
7.97
4.95
mmol/24h
4.22
118
31
116
123
20.18
109.45
3.8
3.7
60.46
76.39
ng/l
1.52
104
113
107
202
9.89
61.81
2.8
6.8
0.91
1.03
mmol/l
4.70
99
190
159
680
6.77
34.72
4.4
2.3
77.89
76.96
nmol/l
0.18
146
607
170
795
7.37
32.78
10.1
7.4
1.23
1.22
mmol/l
2.10
147
689
159
734
6.03
30.10
8.4
6.4
1.23
1.22
mmol/l
1.53
149
670
48
93
6.42
25.02
3.1
2.3
45.17
40.87
u/l
0.50
41
80
19
10
20.74
13.18
1.7
1.1
166.79
180.57
mmol/24h
—
19
10
92
461
2.79
11.62
2.3
2.9
335.85
5336.92
umol/l
1.68
80
403
63
273
2.88
10.29
2.2
3.8
0.83
0.83
mmol/l
0.30
57
259
177
1301
3.49
9.91
4.5
4.2
8.31
10.56
mm/h
1.58
166
1198
99
548
2.55
9.85
3.6
3.3
2.35
2.35
mmol/l
0.14
86
485
177
1345
3.18
8.45
6.9
8.1
77.36
77.47
u/l
0.01
170
1261
32
119
3.00
6.72
1.7
3.4
68.76
66.60
g/l
1.25
27
109
40
174
2.61
6.26
2.5
2.0
345.65
382.61
nmol/l
0.54
40
161
71
404
2.15
6.02
1.4
1.3
1.13
1.25
u/ml
0.08
20
109
86
536
2.03
5.66
2.3
2.5
56.37
54.71
u/l
0.22
78
490
92
588
2.02
5.64
4.0
2.9
—
—
—
0
0
167
1327
2.34
5.60
4.9
4.0
14.87
14.60
pmol/l
0.72
151
1211
190
1619
3.11
5.20
6.0
4.6
1.82
1.89
mu/l
0.40
171
1489
9
9
10.39
5.07
1.3
1.7
47.60
68.88
ug/l
—
9
9
25
95
2.86
5.03
3.1
4.1
1.81
1.72
mmol/l
0.04
19
70
195
1712
3.40
4.53
5.3
4.5
5.85
5.91
mmol/l
0.32
179
1585
41
212
2.16
4.31
5.4
4.4
33.48
31.82
%
0.44
25
141
14
41
3.59
4.26
3.1
2.7
25.65
24.82
mmol/l
0.31
14
41
39
206
2.10
3.87
5.8
6.7
—
—
—
0
0
98
703
1.75
3.78
3.8
4.8
36.70
36.15
g/l
0.49
92
671
11
25
4.59
3.68
1.4
1.2
—
—
—
0
0
89
626
1.74
3.65
1.7
1.9
104.53
98.18
pmol/l
0.43
41
298
153
1254
1.84
3.65
2.8
3.3
46.00
47.97
u/l
0.14
143
1180
22
95
2.47
3.48
1.0
1.0
—
—
—
0
0
9
18
5.18
3.41
1.0
1.3
—
—
—
0
0
51
310
1.86
3.38
1.3
1.3
18.42
29.76
iu/ml
0.59
16
104
7
11
6.54
3.21
1.7
2.5
358.14
827.27
u/ml
—
7
11
202
1896
3.71
3.00
9.9
10.7
29.65
27.87
u/l
0.66
194
1841
49
305
1.79
2.99
1.3
1.3
16.57
7.51
u/ml
0.31
16
119
187
1674
2.21
2.96
13.3
12.0
85.39
84.54
ml/min/173m2
0.25
164
1354
67
458
1.68
2.94
3.8
2.8
0.18
0.49
e6/l
1.19
54
337
22
103
2.27
2.93
3.0
3.7
4.63
4.56
pmol/l
0.10
17
88
14
53
2.76
2.86
1.6
1.3
—
—
—
0
0
193
1762
2.41
2.70
13.6
13.0
19.05
22.71
mg/l
0.79
155
1362
84
623
1.59
2.61
4.0
3.2
16.64
36.60
ng/l
2.15
62
399
9
25
3.71
2.60
1.3
1.1
—
—
—
0
0
103
807
1.55
2.49
7.0
4.8
0.00
0.00
estimate
-0.00
21
149
97
750
1.55
2.49
7.6
9.4
1.13
1.15
inr
0.10
29
208
103
810
1.54
2.43
5.0
3.5
0.00
0.01
estimate
0.50
20
157
104
821
1.54
2.40
4.9
3.5
0.14
0.00
estimate
0.48
21
140
137
1153
1.56
2.33
3.2
3.1
—
—
—
0
0
120
985
1.52
2.26
5.2
4.8
6.69
6.68
mmol/l
0.02
115
919
181
1643
1.81
2.13
6.3
5.6
39.11
39.61
mmol/mol
0.33
163
1542
193
1795
2.11
2.00
5.4
5.0
2.96
2.85
mmol/l
0.96
177
1669
185
1709
1.78
1.79
4.7
4.0
1.41
1.31
mmol/l
0.99
165
1578
55
400
1.51
1.78
2.5
2.3
—
—
—
0
0
38
254
1.61
1.77
1.5
1.6
1263.89
1226.73
nmol/l
0.09
26
185
41
280
1.58
1.75
3.2
2.5
0.81
0.85
e6/l
0.05
25
157
89
717
1.42
1.69
2.9
2.6
110.58
121.97
ug/l
0.23
83
666
80
633
1.43
1.68
5.0
3.6
—
—
—
0
0
13
63
2.13
1.63
2.4
1.7
—
—
—
0
0
6
20
3.06
1.59
1.8
1.8
—
—
—
0
0
6
20
3.06
1.59
1.8
1.8
—
—
—
0
0
6
20
3.06
1.59
1.8
1.8
—
—
—
0
0
13
64
2.10
1.58
1.4
2.6
—
—
—
0
0
52
383
1.48
1.57
1.8
1.7
1.50
1.11
mg/l
0.22
33
295
5
15
3.39
1.53
3.0
2.2
—
—
—
0
0
6
21
2.91
1.51
1.2
1.4
—
—
—
0
0
67
522
1.42
1.51
4.0
3.9
4.29
8.45
mg/mmol
0.95
45
331
189
1772
1.77
1.51
5.1
4.5
4.82
4.76
mmol/l
0.38
172
1655
188
1762
1.73
1.47
5.3
4.4
1.43
1.47
mmol/l
0.70
172
1634
27
174
1.63
1.46
1.5
1.8
—
—
—
0
0
51
380
1.45
1.45
2.1
1.9
2.60
3.17
mg/l
1.02
44
331
9
39
2.37
1.45
1.3
1.1
—
—
—
0
0
37
259
1.52
1.42
3.3
2.6
1.17
2.66
e6/l
1.03
21
137
11
53
2.14
1.41
1.2
1.1
—
12.84
—
0
8
95
794
1.36
1.39
2.6
2.5
—
—
—
0
0
12
62
1.99
1.30
4.5
7.5
1.57
1.69
%
0.30
12
55
44
326
1.44
1.29
1.6
1.7
422.50
455.89
pmol/l
0.38
34
282
107
921
1.33
1.25
4.3
6.9
10.14
10.67
umol/l
0.40
100
874
10
49
2.09
1.24
1.2
1.2
—
—
—
0
0
5
19
2.67
1.22
2.8
1.7
12.40
13.53
%
—
5
19
5
20
2.54
1.16
2.0
1.8
—
—
—
0
0
11
58
1.95
1.14
1.5
1.1
—
—
—
0
0
20
129
1.61
1.10
1.5
1.2
34.29
118.08
iu/ml
—
8
48
5
21
2.41
1.09
2.0
1.8
—
—
—
0
0
5
21
2.41
1.09
2.0
1.8
—
—
—
0
0
54
429
1.35
1.06
4.9
3.8
0.00
0.01
estimate
0.50
20
146
9
46
2.00
1.05
1.1
1.2
—
1.08
—
0
5
9
52
1.76
0.93
1.4
1.4
—
—
—
0
0
20
138
1.50
0.85
2.0
2.6
65.00
62.47
ml/min/173m2
—
6
59
8
45
1.81
0.85
1.5
1.2
—
—
—
0
0
54
443
1.30
0.85
2.6
3.0
313.16
809.41
ng/l
5.00
45
373
114
1024
1.25
0.84
7.6
10.3
3.56
4.01
e9/l
2.26
102
898
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
0
26
0.00
0.79
0.0
2.1
—
—
—
0
0
71
609
1.25
0.78
2.5
3.8
31.52
31.79
u/l
0.04
71
579
10
60
1.70
0.73
2.4
2.1
—
—
—
0
0
7
41
1.73
0.70
1.7
1.6
—
—
—
0
0
5
91
0.54
0.69
1.4
1.6
—
—
—
0
0
34
270
1.31
0.68
1.6
1.5
—
—
—
0
0
5
29
1.74
0.64
1.2
3.9
61.20
56.86
%
—
5
29
43
357
1.26
0.62
1.4
1.5
25.24
21.59
nmol/l
0.57
36
299
15
105
1.46
0.62
1.6
1.7
—
—
—
0
0
5
30
1.68
0.62
1.8
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.5
—
—
—
0
0
41
341
1.25
0.58
1.5
1.5
—
—
—
0
0
39
323
1.26
0.58
2.6
3.4
168.76
298.65
ng/l
0.35
27
236
43
361
1.24
0.57
5.2
3.8
1.02
1.02
kg/l
0.24
13
50
9
59
1.55
0.55
1.7
1.8
—
—
—
0
0
25
198
1.30
0.52
7.6
7.3
105.44
103.86
mmol/l
0.79
25
198
0
15
0.00
0.41
0.0
1.0
—
578.75
—
0
8
0
15
0.00
0.41
0.0
1.0
—
45.43
—
0
7
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
52
461
1.17
0.40
4.6
4.1
18.66
21.83
%
1.01
27
206
31
264
1.20
0.37
1.7
2.1
—
—
—
0
0
9
71
1.28
0.36
2.2
1.7
—
—
—
0
0
6
43
1.41
0.35
1.2
1.2
—
—
—
0
0
7
56
1.26
0.29
2.3
1.6
—
—
—
0
0
18
151
1.21
0.26
3.7
3.1
—
—
—
0
0
9
73
1.24
0.26
1.4
1.7
—
—
—
0
0
9
75
1.21
0.25
7.0
4.0
59.92
55.37
%
—
9
75
14
168
0.82
0.23
1.9
1.9
—
—
—
0
0
5
40
1.26
0.22
1.6
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
21
184
1.16
0.20
1.6
4.3
5.01
31.24
ug/l
0.59
15
153
17
194
0.87
0.17
1.4
2.0
—
—
—
0
0
16
181
0.87
0.15
2.1
2.0
—
—
—
0
0
36
335
1.09
0.14
2.7
2.8
0.68
0.73
ug/l
0.37
24
204
5
45
1.11
0.10
1.2
1.4
—
—
—
0
0
10
87
1.16
0.09
1.5
1.8
—
—
—
0
0
17
155
1.11
0.09
10.6
9.0
127.88
123.78
g/l
0.37
17
149
8
90
0.88
0.07
1.6
1.3
—
—
—
0
0
8
92
0.86
0.07
1.4
1.3
—
—
—
0
0
20
188
1.07
0.05
1.3
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
52.40
—
0
5
48
480
1.00
-0.00
1.8
1.7
1.39
1.38
mmol/l
0.01
43
405
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
23.28
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.87
-0.00
1.8
2.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
1438.29
—
0
7
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
14.00
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
5.67
—
0
6
5
53
0.94
-0.00
3.0
1.8
—
—
—
0
0
5
55
0.91
-0.00
2.6
1.7
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: E4_IDIOPATHIC_HYPERCALCIURIA – Idiopathic hypercalciuria
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).