Eustachian salpingitis and obstruction

H8_EUSTSALP

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H68
  • Hospital discharge: ICD-9 3816
  • Hospital discharge: ICD-8 3840[0-2]
  • Cause of death: ICD-10 H68
  • Cause of death: ICD-9 3816
  • Cause of death: ICD-8 3840[0-2]

2 out of 7 registries used, show all original rules.

3543

4. Check minimum number of events

None

3543

5. Include endpoints

None

3543

6. Filter based on genotype QC (FinnGen only)

3432

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31754 13543 18131
Only index persons 30023 12880 17143
Unadjusted period prevalence (%)
Whole population 0.45 0.39 0.51
Only index persons 0.58 0.47 0.65
Median age at first event (years)
Whole population 5.11 5.81 4.58
Only index persons 5.10 5.83 4.54

-FinnGen-

Key figures

All Female Male
Number of individuals 3432 1936 1496
Unadjusted period prevalence (%) 0.69 0.69 0.69
Median age at first event (years) 6.67 7.10 6.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3543
Matched controls
35430
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
307.7
409
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
6.7
307.7
614
1077
H65.2
ICD-10 Finland
Chronic serous otitis media
118.0
307.7
242
22
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
238.3
307.7
285
13
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
85.1
307.7
1035
171
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
20.1
307.7
1936
2004
38400
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) acuta
+∞
307.7
469
*
4122
FHL
Tympanostomy (tympanic tube)
149.4
307.7
338
25
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
307.7
764
*
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
307.7
1305
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
180.9
307.7
358
22
UDC00
NOMESCO Finland
Ear microscopy
7.7
307.7
557
839
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
64.1
307.7
267
45
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
245.9
307.7
413
19
DC1AD
NOMESCO Finland
Temporalbone CT
38.9
283.1
174
47
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
282.1
267
*
DFF00
NOMESCO Finland
Pure tone audiometry
5.4
237.7
515
1074
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
225.5
214
*
H66.9
ICD-10 Finland
Otitis media, unspecified
5.4
218.5
472
979
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.1
211.7
677
1921
H68.0
ICD-10 Finland
Eustachian salpingitis
50.1
209.3
121
25
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
27.0
182.1
125
48
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
82.0
165.5
88
11
H65.0
ICD-10 Finland
Acute serous otitis media
11.6
150.3
157
141
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
17.9
142.5
116
67
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
136.3
130
*
DCD00
NOMESCO Finland
Myringoplasty
1262.2
125.8
122
*
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
119.4
114
*
4451
FHL
Guitar cutting
5.0
114.2
257
545
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
6.9
99.1
156
235
H74.1
ICD-10 Finland
Adhesive middle ear disease
501.6
99.0
98
*
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
23.5
93.0
67
29
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
9.5
91.3
109
118
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
16.6
89.2
75
46
R01AD08
ATC
fluticasone; nasal
2.1
87.8
1284
7609
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
42.2
83.1
50
12
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.2
81.8
346
1148
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
19.4
80.7
63
33
H92.0
ICD-10 Finland
Otalgia
3.3
80.7
329
1067
TDA90
NOMESCO Finland
Removal wax from ear
11.2
75.5
80
73
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
73.9
2028
14630
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.7
63.6
363
1417
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.0
61.8
950
5598
R01AD09
ATC
mometasone; nasal
1.8
59.1
1820
13237
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
128.3
59.0
63
5
H69.0
ICD-10 Finland
Patulous Eustachian tube
17.9
56.8
46
26
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
14.9
56.2
50
34
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.1
55.6
159
405
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
12.1
54.9
55
46
4141
FHL
Myringoplasty (also for reasons other than inflammation)
275.2
53.3
54
*
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
53.3
51
*
H01
ICPC
Ear pain/earache
2.2
52.5
478
2306
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
5.5
51.6
100
185
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
51.2
49
*
EMB30
NOMESCO Finland
Adenotomy
5.9
50.1
90
155
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
8.3
48.8
64
78
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
7.5
45.8
66
90
1450
FHL
Otomicroscopy
11.9
45.5
46
39
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
44.9
43
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
44.9
43
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
44.9
43
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.4
42.7
320
1416
H29
ICPC
Ear symptom/complaint other
2.3
39.8
335
1556
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
38.6
37
*
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
7.1
38.6
58
83
50300
ICD-8 Finland
Chronic sinusitis, Maxillaris cum empyemate
10.6
38.4
42
40
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
37.9
1030
7012
ZXA10
NOMESCO Finland
Bilateral
1.9
37.7
503
2778
J01FA10
ATC
azithromycin; systemic
1.6
37.0
2092
16906
R01AD12
ATC
fluticasone furoate; nasal
1.6
37.0
1304
9450
H71
ICPC
Acute otitis media/myringitis
5.1
35.7
76
153
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.9
35.1
173
622
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
34.4
33
*
4452
FHL
Tonsil surgery
2.7
34.3
198
773
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
57.8
34.2
40
7
H60.8
ICD-10 Finland
Other otitis externa
3.2
34.1
135
428
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.5
33.8
120
355
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
33.4
32
*
H02AB06
ATC
prednisolone; systemic
1.5
33.2
1467
11118
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.2
32.4
305
1479
J01CA04
ATC
amoxicillin; systemic
1.7
31.9
2872
25399
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.4
31.8
118
359
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
88.4
31.8
35
*
S02CA02
ATC
flumetasone and antiinfectives; otic
2.8
31.7
169
633
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.3
31.2
122
384
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
3.5
30.6
105
304
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
29.4
790
5308
DFF15
NOMESCO Finland
Speech audiometry
3.3
28.9
111
345
ZXE00
NOMESCO Finland
One hour or less
1.5
26.5
1251
9490
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
34.3
26.5
34
10
H69.9
ICD-10 Finland
Eustachian tube disorder, unspecified
7.6
26.3
37
49
J01DA01
ATC
[U] cefalexin
1.5
26.0
2040
17056
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
25.8
1134
8465
48509
ICD-8 Finland
Bronchopneumonia, unspecified
4.2
25.7
68
164
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
24.2
25.7
36
15
H02AB04
ATC
methylprednisolone; systemic
1.8
25.5
429
2532
H02
ICPC
Hearing complaint
2.1
25.3
268
1357
UDM02
NOMESCO Finland
Sinoscopy
3.4
25.3
92
277
J01FA09
ATC
clarithromycin; systemic
1.5
25.1
1032
7590
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
25.0
24
*
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.8
25.0
128
470
DCD10
NOMESCO Finland
Tympanoplasty
70.4
24.8
28
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.2
24.3
218
1036
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
24.3
371
2125
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.9
24.2
116
411
H13
ICPC
Plugged feeling ear
1.8
23.7
424
2546
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
2.7
22.6
119
444
J01DA08
ATC
[U] cefaclor
1.8
22.5
342
1954
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
2.3
22.3
164
717
R01AD58
ATC
fluticasone, combinations; nasal
1.5
22.3
988
7346
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
22.1
224
1116
J32.4
ICD-10 Finland
Chronic pansinusitis
3.6
22.0
73
207
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
22.0
147
616
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
21.9
180
826
H60.3
ICD-10 Finland
Other infective otitis externa
3.2
21.3
83
261
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.6
21.3
124
487
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
3.2
21.1
84
268
J35.2
ICD-10 Finland
Hypertrophy of adenoids
3.8
21.1
64
171
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.2
20.9
82
259
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
77.3
20.7
23
*
J01AA02
ATC
doxycycline; systemic
1.4
20.6
2467
21794
J01DA06
ATC
[U] cefuroxime
1.7
20.2
425
2661
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
19.8
19
*
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
19.8
19
*
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
15.4
19.7
32
21
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
19.6
311
1798
DEB30
NOMESCO Finland
Radical mastoidectomy
105.6
19.6
21
*
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.4
19.5
70
209
H72
ICD-10 Finland
Perforation of tympanic membrane
34.5
18.9
24
7
J34.2
ICD-10 Finland
Deviated nasal septum
2.0
18.9
202
1027
H61.2
ICD-10 Finland
Impacted cerumen
2.1
18.8
177
858
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
18.8
18
*
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
18.7
301
1748
4221
FHL
Polyp removal from the nasal cavity, sinus puncture or irrigation, or biopsy under general anesthesia or operating room
4.3
18.3
46
107
H60.4
ICD-10 Finland
Cholesteatoma of external ear
19.4
18.2
27
14
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
4.2
18.1
47
112
4741A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PALATINAE]
4.4
18.0
44
100
H61.8
ICD-10 Finland
Other specified disorders of external ear
4.9
17.8
39
81
48609
ICD-8 Finland
Pneumonia, unspecified
3.1
17.8
75
248
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
66.9
17.7
20
*
G47.3
ICD-10 Finland
Sleep apnoea
1.5
17.7
672
4815
H04
ICPC
Ear discharge
2.8
17.4
89
327
R06AE07
ATC
cetirizine; oral
1.4
17.2
1473
12160
J01DB01
ATC
cefalexin; oral
1.4
16.7
2808
25728
SPAT1043
SPAT
Audiometry
2.0
16.6
181
927
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
16.5
1183
9473
R03AC02
ATC
salbutamol; inhalant
1.3
16.5
1802
15395
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
170.8
16.5
17
*
49099
ICD-8 Finland
Bronchitis, unspecified
4.1
16.1
44
109
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
16.1
902
6933
H60
ICD-10 Finland
Otitis externa
1.9
15.9
195
1040
Q35.1
ICD-10 Finland
Cleft hard palate
33.5
15.7
20
6
SPAT1172
SPAT
Guidance concerning hydration
4.2
15.5
41
99
DHB50
NOMESCO Finland
Turbinoplasty
2.3
15.3
112
490
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
15.1
686
5073
R06.0
ICD-10 Finland
Dyspnoea
1.5
15.0
636
4642
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
15.0
951
7447
4224
FHL
Endonasal anthrostomy
3.8
14.8
44
116
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
56.9
14.8
17
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.0
14.7
169
881
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
2.5
14.6
88
352
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
14.6
14
*
N07CA01
ATC
betahistine; oral
2.0
14.6
152
766
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
14.6
1031
8206
DAX08
NOMESCO Finland
Fitting of hearing aid
2.6
14.6
85
335
J01DC02
ATC
cefuroxime; systemic
1.9
14.5
188
1021
4364
FHL
Pharyngeal tongue plastic
27.3
14.3
19
7
S02AA03
ATC
boric acid; otic
4.5
14.2
34
76
R01AD05
ATC
budesonide; nasal
1.7
14.2
241
1421
R42
ICD-10 Finland
Dizziness and giddiness
1.5
14.0
525
3735
A02BC05
ATC
esomeprazole; systemic
1.3
14.0
1135
9214
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
13.9
513
3641
SPAT1263
SPAT
Sampling
1.3
13.9
1217
9990
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
13.7
101
444
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
+∞
13.5
13
*
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
13.5
13
*
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
+∞
13.5
13
*
WX723
NOMESCO Finland
CPAP therapy
2.0
13.5
142
718
4740A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Chronic tonsillitis
2.0
13.5
141
712
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
13.4
968
7713
H92.1
ICD-10 Finland
Otorrhoea
25.8
13.4
18
7
A02BC02
ATC
pantoprazole; systemic
1.3
13.2
1949
17140
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.6
13.2
313
2014
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
13.2
2004
17695
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
13.1
228
1354
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
13.1
312
2012
WX780
NOMESCO Finland
Remote monitoring CPAP
2.0
13.0
150
783
R03AK08
ATC
formoterol and beclometasone; inhalant
2.0
12.9
132
662
J01MA12
ATC
levofloxacin; systemic
1.5
12.8
411
2830
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
3.1
12.8
52
169
J01FF01
ATC
clindamycin; systemic
1.4
12.7
773
5988
H68
ICD-10 Finland
Eustachian salpingitis and obstruction
5.1
12.7
26
51
R5120
NOMESCO Finland
Preparation of an aid
2.9
12.6
57
197
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
70.1
12.6
14
*
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
12.5
12
*
J33.8
ICD-10 Finland
Other polyp of sinus
2.7
12.5
64
237
H73.1
ICD-10 Finland
Chronic myringitis
130.5
12.4
13
*
EMB10
NOMESCO Finland
Tonsillectomy
1.7
12.4
256
1591
WX402
NOMESCO Finland
General anaesthesia
1.4
12.4
633
4759
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
12.3
997
8062
4129
FHL
Other measure in this category
37.7
12.2
15
*
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.0
12.2
129
655
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
12.0
563
4168
50709
ICD-8 Finland
Hay fever, Unspecified
5.2
12.0
24
46
H02AB07
ATC
prednisone; oral
1.5
11.9
332
2219
74920
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis unilateralis
19.0
11.6
17
9
N02BE01
ATC
paracetamol; systemic, rectal
1.4
11.5
2813
26230
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
11.5
1226
10273
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
11.4
1316
11132
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
4.1
11.4
31
77
M01AE02
ATC
naproxen; oral, rectal
1.3
11.4
1792
15764
SPAT1153
SPAT
Removal of sutures
1.4
11.4
697
5395
J01DA09
ATC
[U] cefadroxil
1.3
11.4
784
6179
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
11.3
488
3559
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
3.8
11.2
33
87
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
11.2
618
4703
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
11.1
136
726
R03BA05
ATC
fluticasone; inhalant
1.4
11.0
519
3845
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
10.9
258
1660
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
1.9
10.9
129
682
R03DC03
ATC
montelukast; oral
1.4
10.8
511
3784
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
10.8
166
951
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
10.7
2376
21716
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
10.7
507
3756
ZFX00
NOMESCO Finland
Use of balloon dilatation
21.5
10.7
15
7
J01FA01
ATC
erythromycin; systemic
1.4
10.6
450
3268
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
10.6
449
3260
1451
FHL
Otomicroscopy and paper place
60.2
10.6
12
*
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.2
10.6
85
388
R06AX27
ATC
desloratadine; oral
1.3
10.6
1023
8440
J01FA15
ATC
telithromycin; oral
1.5
10.6
289
1922
4151
FHL
Reoperation for chronic otitis media
110.3
10.4
11
*
DCB10
NOMESCO Finland
Freeing of adhesions of middle ear
110.3
10.4
11
*
38200
ICD-8 Finland
Acute / Acute otitis media with mastoiditis
+∞
10.4
10
*
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
10.4
10
*
J01MA02
ATC
ciprofloxacin; systemic
1.3
10.4
961
7881
J02AC01
ATC
fluconazole; systemic
1.3
10.4
1238
10488
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
10.3
661
5143
J01FA06
ATC
roxithromycin; oral
1.3
10.3
1134
9506
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
8.2
10.3
22
27
J01DC04
ATC
cefaclor; oral
3.0
10.3
45
153
DPA30
NOMESCO Finland
Sphenotomy
3.9
10.3
29
74
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
10.3
333
2297
UJF32
NOMESCO Finland
Coloscopy
1.4
10.1
545
4124
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
7.9
10.1
22
28
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
3.8
10.0
30
80
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
14.6
10.0
16
11
DCA30
NOMESCO Finland
Exploration of middle ear
40.2
10.0
12
*
AA1AD
NOMESCO Finland
CT of head and brain
1.4
9.9
540
4092
H93.1
ICD-10 Finland
Tinnitus
1.7
9.8
178
1072
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.2
9.7
83
390
R01AD11
ATC
triamcinolone; nasal
1.6
9.6
253
1669
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
100.3
9.4
10
*
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
100.3
9.4
10
*
7490B
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS INCOMPLETA]
+∞
9.4
9
*
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
9.4
9
*
A02BC01
ATC
omeprazole; systemic
1.3
9.4
636
4985
M01AH05
ATC
etoricoxib; oral
1.2
9.4
1977
17816
R01AD01
ATC
beclometasone; nasal
1.4
9.3
475
3560
R4135
NOMESCO Finland
Rehabilitation for hearing problems
4.0
9.3
26
66
H73.0
ICD-10 Finland
Acute myringitis
4.7
9.3
21
45
D82
ICPC
Teeth/gum disease
1.3
9.2
1221
10434
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
9.2
1004
8388
E0000UV, ,
ATC
1.3
9.2
1205
10289
SPAT1211
SPAT
Application of soft bandage
1.6
9.1
193
1209
R74
ICPC
Upper respiratory infection acute
1.3
9.1
1185
10109
WX320
NOMESCO Finland
Spinalanesthesy
1.3
9.0
558
4311
N02AX02
ATC
tramadol; systemic, rectal
1.3
9.0
1099
9298
ZXA00
NOMESCO Finland
Right side
1.4
9.0
543
4181
H70
ICPC
Otitis externa
2.4
8.9
61
261
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.8
8.9
125
699
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
8.8
2354
21700
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
8.8
324
2291
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
8.8
1788
15997
WX002
NOMESCO Finland
Sedation and analgesia
1.4
8.8
416
3078
R01BA01
ATC
phenylpropanolamine; oral
1.8
8.8
128
724
J37.0
ICD-10 Finland
Chronic laryngitis
2.0
8.7
85
421
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
50.1
8.7
10
*
M79.6
ICD-10 Finland
Pain in limb
1.3
8.7
1182
10120
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
8.5
559
4356
J20
ICD-10 Finland
Acute bronchitis
1.5
8.5
280
1938
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
20.1
8.5
12
6
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
8.4
1320
11465
H74.0
ICD-10 Finland
Tympanosclerosis
90.3
8.4
9
*
3851A
ICD-9 Finland
Other disorders of middle ear and mastoid, Adhesive middle ear disease
+∞
8.3
8
*
4362
FHL
Nozzle reconstruction
+∞
8.3
8
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
8.3
929
7762
M03BX02
ATC
tizanidine; oral
1.2
8.2
2081
18993
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
2.4
8.2
53
221
N03AX16
ATC
[U] pregabalin
1.3
8.2
561
4399
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.8
8.1
128
741
R06AX13
ATC
loratadine; oral
1.3
8.1
485
3725
H91
ICD-10 Finland
Other hearing loss
3.8
8.1
24
64
H65
ICD-10 Finland
Nonsuppurative otitis media
2.7
8.1
42
158
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
3.0
8.0
33
109
SPAT1262
SPAT
Handing over of treatment supplies
1.4
7.9
364
2680
ZXA05
NOMESCO Finland
Left side
1.3
7.9
492
3804
L15
ICPC
Knee symptom/complaint
1.3
7.9
540
4233
H81.3
ICD-10 Finland
Other peripheral vertigo
2.3
7.8
57
251
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
2.1
7.8
73
356
SPAT1310
SPAT
Counselling related to known health issue
1.3
7.7
776
6393
Q35.9
ICD-10 Finland
Cleft palate, unspecified
45.1
7.7
9
*
74929
ICD-8 Finland
Cleft palate and cleft lip, Unspecified
45.1
7.7
9
*
R96
ICPC
Asthma
1.5
7.7
210
1398
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
7.7
493
3826
RK520, ,
NOMESCO Finland
7.4
7.7
17
23
SGA01
NOMESCO Finland
Emergency treatment
1.3
7.6
587
4672
XLA10, ,
NOMESCO Finland
1.8
7.6
118
682
J45
ICD-10 Finland
Asthma
1.4
7.6
286
2034
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.5
7.5
246
1700
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
7.5
638
5144
05209
ICD-8 Finland
Chickenpox, Unspecified
4.1
7.5
20
49
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.1
7.5
67
321
P01AB01
ATC
metronidazole; oral, rectal
1.2
7.5
1137
9810
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
7.5
155
968
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
3.0
7.5
31
103
R05FB02
ATC
cough suppressants and expectorants; systemic
1.3
7.4
867
7273
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
1.7
7.4
129
771
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
7.4
211
1420
SPAT1312
SPAT
General health counselling
1.3
7.3
838
7010
3816A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Obstruction of Eustachian tube
+∞
7.3
7
*
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
6.8
7.3
17
25
R02
ICPC
Shortness of breath/dyspnoea
1.4
7.2
265
1874
1290
FHL
Epipharyngoscopy
15.8
7.2
11
7
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
7.2
2437
22750
SPAT1377
SPAT
Polysomnography
1.9
7.2
91
494
R03CC02
ATC
salbutamol; systemic
1.7
7.2
132
799
S01AA01
ATC
chloramphenicol; ophthalmic
1.7
7.2
113
656
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
7.1
587
4712
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
1.5
7.1
227
1561
50499
ICD-8 Finland
Deflected nasal septum
3.6
7.1
23
65
R55
ICD-10 Finland
Syncope and collapse
1.5
7.1
205
1381
R03AC03
ATC
terbutaline; inhalant
1.4
7.0
378
2855
A99
ICPC
Disease/condition unspecnature/site
1.5
7.0
202
1361
Y0599
ICD-8 Finland
Investigation of digestive system
2.6
7.0
39
152
L90
ICPC
Osteoarthrosis of knee
1.9
7.0
89
484
ZXC10
NOMESCO Finland
Use of laser
2.2
7.0
57
264
UKC02
NOMESCO Finland
Cystoscopy
1.5
7.0
251
1768
S02AA30
ATC
antiinfectives, combinations; otic
1.8
6.9
102
581
S18
ICPC
Laceration/cut
1.2
6.9
1076
9296
Z01.2
ICD-10 Finland
Dental examination
1.2
6.9
1437
12779
R51.80
ICD-10 Finland
Headache
1.3
6.9
490
3859
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
6.8
970
8301
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
3.0
6.8
29
98
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
9.3
6.8
13
14
P85
ICPC
Mental retardation
9.3
6.8
13
14
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.3
6.7
777
6497
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
22.6
6.7
9
*
DC1AI
NOMESCO Finland
Cone beam CT of ear
22.6
6.7
9
*
UDC10
NOMESCO Finland
Tympanoscopy
22.6
6.7
9
*
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
6.7
275
1988
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
2.9
6.6
30
105
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.4
6.5
259
1860
J01.1
ICD-10 Finland
Acute frontal sinusitis
2.1
6.4
61
300
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.8
6.4
90
505
38410, ,
ICD-8 Finland
70.0
6.4
7
*
Q90
ICD-10 Finland
Down syndrome
70.0
6.4
7
*
50708
ICD-8 Finland
Hay fever, Alia definita
7.4
6.4
14
19
H72
ICPC
Serous otitis media
14.3
6.4
10
7
R03AK11
ATC
formoterol and fluticasone; inhalant
2.0
6.3
68
350
J01
ICD-10 Finland
Acute sinusitis
1.5
6.3
180
1211
XKD00
NOMESCO Finland
Uroflowmetry
1.5
6.3
206
1427
SPAT1260
SPAT
Consultation of another employee
1.3
6.3
385
2967
DDA00
NOMESCO Finland
Stapedotomy
3.3
6.3
22
66
H77
ICPC
Perforation ear drum
18.0
6.3
9
5
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
+∞
6.3
6
*
DEB35
NOMESCO Finland
Radical mastoidectomy with tympanoplasty
+∞
6.3
6
*
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
6.3
6
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
6.2
252
1815
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.5
6.2
166
1101
N03AX12
ATC
[U] gabapentin; oral
1.3
6.2
388
2997
R06.5
ICD-10 Finland
Mouth breathing
1.4
6.2
247
1774
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.5
6.2
189
1290
RK320, ,
NOMESCO Finland
3.7
6.2
19
52
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
2.0
6.2
62
312
R03BA02
ATC
budesonide; inhalant
1.3
6.2
481
3832
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.2
2084
19292
J30.0
ICD-10 Finland
Vasomotor rhinitis
1.9
6.2
69
361
R52.9
ICD-10 Finland
Pain, unspecified
1.4
6.2
242
1735
A02BA02
ATC
ranitidine; systemic
1.3
6.1
361
2765
J35.1
ICD-10 Finland
Hypertrophy of tonsils
2.0
6.1
61
306
PD5AD
NOMESCO Finland
CT of aorta
2.4
6.1
40
169
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
2.4
6.1
40
169
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.1
2015
18605
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
6.1
571
4654
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
6.1
547
4437
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.4
6.0
216
1523
DHA10
NOMESCO Finland
Biopsy of cavity of nose
3.2
6.0
23
73

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
540
3016
1.93
39.24
2.0
1.6
—
—
—
0
0
876
5701
1.71
38.25
3.3
2.9
—
—
—
0
0
1201
9352
1.43
20.94
9.9
9.0
1.12
1.13
inr
0.12
446
3004
412
2545
1.70
20.65
3.8
3.5
30.06
30.53
%
0.38
300
1935
371
2312
1.68
17.90
3.5
3.2
—
—
—
0
0
1220
9730
1.39
17.80
6.0
5.7
1.22
1.21
mmol/l
1.04
1115
9033
291
1723
1.75
16.91
3.7
3.4
1.22
1.23
mmol/l
2.15
260
1511
2268
20091
1.36
16.23
4.3
3.7
9.31
9.00
mm/h
0.68
2115
18960
1330
10888
1.35
16.02
6.5
6.3
1.21
1.21
mmol/l
0.48
1075
9325
1535
12846
1.34
15.96
6.5
6.3
0.70
0.68
%
0.38
1436
12148
2075
18165
1.34
15.87
4.1
3.7
—
—
—
0
0
1578
13295
1.34
15.53
6.5
6.2
2.90
2.85
%
0.47
1483
12616
1571
13234
1.34
15.45
7.4
6.7
—
—
—
0
0
2229
19807
1.34
14.93
7.4
6.9
73.63
73.66
u/l
0.01
2105
18894
1661
14158
1.33
14.84
4.7
4.4
6.45
6.50
mmol/l
0.41
1532
13076
1607
13653
1.32
14.60
6.1
6.1
56.70
56.39
%
0.55
1524
13001
1578
13373
1.32
14.59
6.7
6.5
8.22
8.27
%
0.32
1487
12715
111
499
2.26
14.26
3.5
3.3
2.26
2.13
mmol/l
0.19
82
296
1471
12388
1.32
14.04
9.4
8.4
0.00
0.00
e9/l
0.14
1212
10147
1621
13847
1.31
13.93
6.5
6.2
28.91
29.26
%
0.77
1536
13196
123
594
2.11
13.25
4.0
3.9
57.72
57.02
%
0.24
123
594
1030
8318
1.34
12.91
3.0
2.7
33.02
40.52
ng/l
0.29
535
4162
120
580
2.11
12.90
3.9
3.6
3.92
4.01
e9/l
0.18
120
580
299
1919
1.61
12.76
3.6
3.7
—
—
—
0
0
1285
10814
1.30
11.68
1.9
1.9
—
—
—
0
0
585
4389
1.40
11.55
2.7
2.8
718.05
884.55
ng/l
0.71
461
3562
3078
29149
1.43
11.23
12.5
10.7
20.32
20.49
mg/l
0.09
2433
22272
1628
14189
1.27
10.99
6.3
6.2
0.04
0.04
e9/l
0.20
1439
12570
1626
14170
1.27
10.98
6.3
6.2
0.55
0.55
e9/l
0.07
1437
12571
57
214
2.69
10.85
2.6
2.5
—
—
—
0
0
396
2803
1.46
10.74
6.5
6.6
1.05
1.04
mmol/l
0.18
376
2651
1671
14652
1.27
10.57
6.2
6.2
1.96
1.97
e9/l
0.08
1514
13272
426
3075
1.44
10.41
1.5
1.4
—
—
—
0
0
75
329
2.31
10.30
1.7
1.7
1.87
1.70
mmol/l
0.52
75
324
1671
14698
1.26
10.13
6.5
6.5
0.19
0.19
e9/l
0.77
1501
13230
1174
9911
1.28
10.02
4.8
4.9
36.73
36.99
g/l
0.92
1091
9323
1457
12629
1.26
9.96
5.7
5.6
10.35
10.87
umol/l
1.05
1357
12010
595
4586
1.36
9.84
2.7
2.6
552.28
550.75
mosm/kgh2o
0.05
536
3940
2415
22264
1.27
9.39
4.4
3.9
14.45
14.43
pmol/l
0.18
2224
20913
2551
27156
0.78
9.17
14.1
13.3
333.90
333.92
g/l
0.04
2529
26979
142
822
1.76
9.00
3.7
3.4
24.43
24.79
mmol/l
1.10
137
772
470
3538
1.38
8.97
3.6
3.7
0.83
0.83
mmol/l
0.03
450
3350
89
443
2.04
8.96
2.6
2.1
16.98
17.24
%
0.17
33
226
318
2239
1.46
8.85
3.3
2.5
10.31
10.58
g/l
0.69
291
2075
1784
15954
1.24
8.84
8.6
9.2
4.02
4.01
e9/l
0.05
1554
14134
448
3377
1.37
8.46
1.9
1.7
1184.23
1164.21
nmol/l
0.16
331
2659
310
2192
1.45
8.43
1.3
1.3
298.19
226.20
u/ml
0.28
292
2049
201
1301
1.58
8.32
3.7
3.0
7.41
7.41
ph
0.05
26
168
59
257
2.32
8.31
3.8
2.9
—
—
—
0
0
252
1719
1.50
8.22
1.8
1.8
1.21
1.28
g/l
0.36
232
1619
70
330
2.14
8.16
1.3
1.3
—
—
—
0
0
935
7841
1.26
8.09
2.8
2.6
57.02
58.15
u/l
0.19
856
7364
2782
26246
1.28
8.08
5.0
4.5
1.72
2.02
mu/l
1.44
2583
24835
2382
22077
1.24
8.07
3.2
3.0
43.37
41.78
u/l
0.45
2247
21227
151
918
1.67
8.05
3.7
3.2
—
—
—
0
0
282
1977
1.46
8.03
4.4
4.2
0.62
0.66
%
0.10
77
584
201
1315
1.56
7.95
3.7
3.0
5.16
5.15
kpa
0.12
191
1262
783
6441
1.28
7.93
4.4
4.0
7.40
7.40
ph
0.20
227
1269
923
7768
1.25
7.68
2.8
2.7
—
—
—
0
0
549
4328
1.32
7.67
1.4
1.4
417.02
554.30
titre
0.99
94
821
1253
10909
1.23
7.63
2.4
2.3
73.53
72.95
nmol/l
0.31
1155
10210
373
2777
1.38
7.59
2.1
2.1
359.69
363.00
nmol/l
0.15
344
2573
2634
24771
1.25
7.38
4.9
4.4
38.23
38.15
mmol/mol
0.17
2445
23577
275
1964
1.43
7.11
4.5
4.5
0.06
0.61
%
1.09
68
474
436
3363
1.34
7.07
1.2
1.2
—
—
—
0
0
1010
8653
1.23
7.05
1.9
1.8
98.99
97.94
pmol/l
0.28
539
4783
609
4921
1.29
7.03
1.3
1.3
7.53
9.05
u/ml
0.27
233
2165
2945
28106
1.28
7.00
12.8
10.9
139.59
139.59
mmol/l
0.02
2865
27393
1466
13058
1.21
6.91
3.1
3.1
0.00
0.00
estimate
0.01
367
2627
284
2053
1.42
6.87
4.5
4.5
0.06
0.11
%
0.61
77
561
438
3396
1.33
6.85
2.0
2.0
—
—
—
0
0
1464
13052
1.21
6.80
4.3
4.2
0.00
0.00
estimate
0.24
360
2564
52
237
2.21
6.66
1.4
1.2
2.92
1.93
u/ml
0.32
18
121
110
649
1.72
6.62
1.7
1.4
24.54
5.91
iu/ml
—
5
16
2793
26538
1.25
6.58
3.9
3.5
5.76
5.74
mmol/l
0.47
2569
24970
159
1032
1.57
6.57
1.9
1.6
6.31
10.01
u/ml
—
7
42
1528
13717
1.20
6.50
3.1
2.9
111.82
95.96
ug/l
0.68
1440
13055
2951
28232
1.27
6.46
13.1
11.0
3.93
3.94
mmol/l
1.16
2856
27451
795
6692
1.24
6.45
2.0
2.1
155.16
246.55
u/l
2.47
746
6383
1823
16638
1.20
6.45
4.0
3.5
1215.41
1089.26
e6/l
0.04
19
175
1468
13140
1.20
6.42
3.1
3.1
0.01
0.01
estimate
0.30
343
2452
373
2871
1.33
6.13
1.3
1.4
—
—
—
0
0
65
334
1.96
6.11
1.6
1.3
0.33
0.41
g/l
1.11
38
234
291
2157
1.38
6.10
4.4
4.4
0.64
0.95
%
1.17
83
666
65
335
1.96
6.06
1.6
1.3
6.13
6.86
g/l
1.24
37
236
65
335
1.96
6.06
1.6
1.3
3.08
3.13
g/l
0.07
38
235
906
7781
1.22
6.02
2.4
2.1
—
—
—
0
0
768
6491
1.23
5.95
1.5
1.4
2.19
2.28
g/l
1.09
496
4322
567
4632
1.27
5.94
1.7
1.6
36044405.50
30820822.30
pmol/l
0.07
455
4059
65
338
1.94
5.92
1.6
1.4
—
—
—
0
0
746
6290
1.24
5.91
1.7
1.8
0.83
0.88
mg/l
0.28
546
4527
696
5831
1.24
5.84
2.3
2.1
—
—
—
0
0
85
484
1.77
5.83
4.4
2.9
—
—
—
0
0
712
5993
1.24
5.71
2.3
2.2
2.67
2.77
mg/l
0.66
604
5205
125
794
1.60
5.70
3.1
3.5
0.42
0.35
g/l
0.20
62
377
141
926
1.54
5.58
1.5
1.9
1.18
1.17
g/l
0.11
133
882
773
6587
1.22
5.49
1.7
1.6
1.49
1.44
mmol/l
0.69
636
5776
73
405
1.82
5.48
1.3
1.4
—
—
—
0
0
136
894
1.54
5.37
1.5
1.9
0.24
0.23
g/l
0.48
129
852
648
5461
1.23
5.10
4.5
4.1
—
—
—
0
0
1401
12669
1.18
5.07
2.6
2.3
—
—
—
0
0
3204
31145
1.30
4.98
9.8
8.6
28.93
28.38
u/l
0.70
3089
30404
104
655
1.61
4.96
1.4
1.4
296.16
297.37
ug/g
0.02
55
334
782
6738
1.21
4.91
3.3
3.4
0.00
0.01
estimate
2.03
354
2482
89
543
1.66
4.83
1.9
1.7
0.74
0.76
g/l
0.04
60
417
694
5922
1.21
4.81
2.5
2.5
—
—
—
0
0
450
3673
1.26
4.73
2.6
2.3
13.78
14.39
umol/l
1.05
423
3442
112
729
1.55
4.67
1.2
1.3
3.24
3.56
u/ml
—
8
75
262
2001
1.33
4.58
2.3
2.4
4.22
5.16
e9/l
1.59
214
1755
113
741
1.54
4.57
1.2
1.3
13.59
9.76
u/ml
0.20
14
126
117
776
1.53
4.50
2.2
2.0
1.42
1.41
g/l
0.05
94
674
17
54
3.16
4.48
1.2
1.2
—
—
—
0
0
17
54
3.16
4.48
1.2
1.2
—
—
—
0
0
17
54
3.16
4.48
1.2
1.2
—
—
—
0
0
689
5917
1.20
4.44
4.4
4.0
10.08
9.53
mg/mmol
0.13
424
3963
749
6492
1.19
4.36
2.4
2.3
1587.85
3610.37
umol/l
1.74
672
5925
146
1021
1.45
4.34
1.2
1.2
—
—
—
0
0
146
1024
1.44
4.27
1.7
1.7
—
—
—
0
0
553
4672
1.22
4.21
1.5
1.5
20.23
20.24
nmol/l
0.00
465
4172
117
788
1.50
4.21
5.3
3.9
1.41
1.28
mg/l
1.11
112
746
234
1781
1.34
4.21
9.6
8.6
7.98
7.87
mmol/l
0.10
225
1712
659
5672
1.20
4.13
3.7
3.4
152.02
427.06
mg/l
1.72
413
3777
858
7558
1.18
4.12
2.8
3.1
2.34
2.34
mmol/l
1.20
742
6912
569
4833
1.21
4.10
2.5
2.4
6.74
6.21
e6/l
0.32
525
4331
61
353
1.74
4.07
1.6
1.6
—
—
—
0
0
514
4326
1.22
4.07
2.7
2.7
116.15
112.87
ug/g
0.10
406
3525
376
3063
1.25
4.03
2.8
2.5
22.93
24.43
%
1.42
318
2671
742
6469
1.19
4.02
3.2
2.8
0.25
0.32
e6/l
0.92
577
4789
405
3331
1.24
3.98
2.7
2.4
2.43
2.42
g/l
0.16
374
3101
3395
33390
1.40
3.94
18.3
15.7
41.06
41.26
%
0.63
3254
31977
3177
30972
1.25
3.94
11.9
9.7
—
—
—
0
0
33
157
2.11
3.93
2.7
2.1
681.79
640.20
ml
0.15
24
110
263
2058
1.30
3.90
2.9
2.5
0.23
0.23
g/l
0.38
253
1929
32
152
2.12
3.83
1.0
1.1
8.09
12.68
u/ml
—
7
29
3402
33485
1.40
3.78
18.2
15.7
6.73
6.65
e9/l
1.31
3324
32766
118
815
1.46
3.78
1.2
1.3
52.20
21.73
u/ml
—
7
46
36
180
2.01
3.78
1.2
1.1
29.33
32.56
u/ml
—
9
18
388
3196
1.24
3.77
1.2
1.2
—
—
—
0
0
2952
28596
1.19
3.75
3.9
3.6
1.39
1.42
mmol/l
3.43
2768
27327
2693
25891
1.17
3.74
13.9
13.0
14.46
14.38
%
0.16
2644
25492
1899
17816
1.14
3.74
3.1
2.9
—
—
—
0
0
35
174
2.02
3.73
1.0
1.1
—
—
—
0
0
3402
33498
1.39
3.64
18.2
15.8
138.48
138.72
g/l
0.45
3351
33182
3396
33433
1.38
3.60
18.2
15.7
260.29
258.70
e9/l
0.76
3323
32786
3400
33479
1.39
3.60
18.1
15.7
4.62
4.63
e12/l
0.21
3319
32792
3399
33470
1.38
3.58
18.0
15.6
30.10
30.10
pg
0.05
3346
33164
3399
33473
1.38
3.54
18.0
15.6
89.95
89.91
fl
0.21
3347
33168
803
7123
1.16
3.48
3.2
2.8
28.90
107.17
e6/l
2.23
630
5352
2958
28706
1.18
3.44
3.9
3.6
4.76
4.80
mmol/l
1.44
2777
27498
2851
27594
1.17
3.38
3.5
3.3
1.35
1.32
mmol/l
1.46
2672
26274
129
929
1.40
3.34
3.3
3.1
—
—
—
0
0
228
1794
1.29
3.28
1.6
1.6
262.22
293.10
mu/l
1.01
199
1634
53
316
1.69
3.25
2.8
2.8
1.35
1.31
e9/l
0.09
48
278
27
129
2.10
3.23
2.9
2.2
513.55
505.18
min
0.18
20
101
40
220
1.83
3.23
1.1
1.1
1.06
1.04
ratio
0.34
19
84
950
8575
1.15
3.22
3.6
3.3
77.20
65.21
e6/l
0.19
675
5847
162
1222
1.34
3.17
1.9
1.7
—
—
—
0
0
1179
10817
1.13
3.10
2.8
2.9
5.93
5.92
ph
0.02
128
1275
11
30
3.67
3.08
1.2
1.1
—
—
—
0
0
156
1176
1.34
3.07
1.2
1.3
0.18
1.13
u/ml
—
8
108
732
6506
1.16
3.06
3.2
2.7
—
—
—
0
0
10
26
3.85
2.97
1.2
1.2
—
—
—
0
0
250
2017
1.26
2.97
3.5
3.5
4.46
4.62
pmol/l
1.90
230
1822
68
443
1.55
2.95
1.9
2.0
5.17
5.26
mmol/24h
0.08
61
404
598
5248
1.17
2.95
1.3
1.3
25.64
24.02
iu/ml
0.15
184
1626
404
3429
1.20
2.95
1.4
1.4
—
—
—
0
0
25
121
2.07
2.92
1.7
1.4
—
—
—
0
0
829
7459
1.15
2.91
1.3
1.3
2.46
1.58
u/ml
0.68
236
2232
66
429
1.55
2.90
3.2
3.9
—
—
—
0
0
20
89
2.25
2.86
1.3
1.4
—
—
—
0
0
2970
28929
1.16
2.83
4.1
3.8
2.92
2.94
mmol/l
0.56
2767
27583
232
1873
1.26
2.76
1.3
1.2
—
—
—
0
0
38
218
1.75
2.72
4.8
3.8
—
—
—
0
0
13
48
2.71
2.71
1.8
3.0
—
—
—
0
0
24
118
2.04
2.71
1.5
1.4
—
—
—
0
0
1306
12136
1.12
2.71
2.6
2.4
—
—
—
0
0
222
1789
1.26
2.69
7.1
7.5
1.17
1.34
mmol/l
2.83
214
1746
179
1405
1.29
2.68
2.4
2.4
66.53
67.49
g/l
0.93
168
1318
1048
9620
1.13
2.67
3.3
3.3
30.65
31.47
u/l
0.35
1000
9173
107
781
1.38
2.63
2.3
2.3
9.08
10.61
mg/l
1.33
98
741
18
80
2.26
2.60
1.4
1.3
—
—
—
0
0
7
15
4.67
2.59
2.4
3.1
—
—
—
0
0
6
11
5.46
2.54
1.0
1.7
—
—
—
0
0
41
246
1.67
2.53
2.8
2.3
12.93
14.09
%
0.34
41
241
93
671
1.40
2.47
2.2
2.1
1.29
1.74
ug/l
0.33
81
608
216
1756
1.25
2.45
9.3
8.7
—
—
—
0
0
771
6980
1.13
2.44
4.1
3.4
8.01
8.56
mmol/l
2.31
650
6174
304
2566
1.20
2.39
1.4
1.4
24.33
21.83
iu/l
0.62
254
2214
134
1030
1.31
2.38
2.4
2.2
—
—
—
0
0
144
1118
1.30
2.38
2.1
2.0
—
—
—
0
0
41
251
1.64
2.36
2.8
2.3
73.34
73.36
%
0.00
41
243
7
17
4.12
2.36
2.6
3.0
—
—
—
0
0
249
2066
1.22
2.34
2.8
2.8
1.65
1.72
%
0.68
218
1865
49
315
1.56
2.32
3.1
4.0
153.93
1198.56
u/ml
0.72
44
299
76
536
1.43
2.31
2.5
2.4
5.39
6.92
umol/l
0.55
51
396
81
579
1.41
2.29
1.7
1.5
—
—
—
0
0
95
699
1.37
2.27
2.7
2.7
—
—
—
0
0
223
1838
1.23
2.25
1.4
1.4
—
—
—
0
0
213
2578
0.82
2.22
1.7
1.6
—
—
—
0
0
33
195
1.70
2.19
2.8
2.4
1.03
1.55
g/24h
0.52
19
111
224
1854
1.22
2.18
1.2
1.2
—
—
—
0
0
25
136
1.84
2.17
1.0
1.1
—
—
—
0
0
532
4737
1.14
2.17
1.7
1.7
—
—
—
0
0
21
108
1.95
2.15
2.3
2.3
—
—
—
0
0
45
290
1.56
2.13
1.5
1.7
1.50
1.38
promille
0.21
32
226
411
3598
1.16
2.12
1.8
1.9
—
—
—
0
0
224
1869
1.21
2.03
4.4
4.3
1.70
1.82
mmol/l
0.24
191
1568
716
6528
1.12
2.00
4.0
3.7
94.55
94.85
%
0.12
698
6354
21
111
1.90
2.00
1.1
1.1
—
—
—
0
0
469
5261
0.87
1.98
1.3
1.3
—
—
—
0
0
16
77
2.08
1.96
1.4
1.2
16.38
11.47
u/l
0.71
16
70
24
134
1.80
1.95
2.0
1.6
—
—
—
0
0
5
11
4.55
1.94
1.0
1.7
—
—
—
0
0
129
1018
1.28
1.94
9.7
11.2
—
—
—
0
0
9
33
2.73
1.93
1.0
1.1
—
—
—
0
0
344
2995
1.16
1.92
2.9
2.7
7.06
7.15
umol/l
0.03
287
2565
15
71
2.12
1.92
1.1
1.6
—
—
—
0
0
158
1283
1.24
1.87
1.3
1.3
—
—
—
0
0
135
1077
1.26
1.87
2.1
2.2
20.39
20.91
s
1.01
114
902
83
620
1.35
1.86
1.1
1.1
9.02
12.82
au/ml
—
6
48
20
107
1.87
1.86
1.3
1.4
66.47
101.05
nmol/24h
2.01
20
107
66
475
1.40
1.85
2.4
2.5
—
—
—
0
0
6
17
3.53
1.83
2.7
2.1
—
—
—
0
0
728
6679
1.11
1.82
1.7
1.7
—
—
—
0
0
375
3305
1.15
1.79
2.1
2.3
29.71
29.56
s
0.17
367
3195
23
131
1.76
1.77
1.6
1.4
1086.61
2574.95
e6/l
3.01
18
91
76
565
1.35
1.77
3.4
3.2
0.87
0.83
nmol/l
0.17
66
493
33
208
1.59
1.76
1.4
1.3
78.48
77.04
umol/l
0.12
33
208
200
1677
1.20
1.76
1.5
1.4
—
—
—
0
0
173
1431
1.22
1.75
1.4
1.4
8.59
8.33
u/l
0.09
137
1173
31
193
1.61
1.74
3.2
3.0
—
—
—
0
0
634
5789
1.12
1.73
3.5
3.1
2.06
1.62
ug/l
0.63
553
5315
58
414
1.41
1.73
1.2
1.1
1.40
1.45
g/l
0.51
52
378
173
1434
1.22
1.72
2.8
2.9
68.32
72.00
e9/l
0.69
131
1053
64
867
0.73
1.70
9.4
8.1
—
—
—
0
0
47
324
1.46
1.69
1.4
1.3
—
—
—
0
0
176
1465
1.21
1.68
5.0
4.2
105.31
83.15
ng/l
1.10
159
1334
24
141
1.71
1.68
2.6
2.7
38.30
47.09
umol/l
0.84
18
129
75
562
1.34
1.67
1.1
1.1
—
—
—
0
0
23
134
1.72
1.66
1.1
1.1
—
—
—
0
0
34
220
1.55
1.64
1.6
2.3
—
—
—
0
0
20
112
1.79
1.64
1.0
1.0
—
—
—
0
0
104
820
1.28
1.62
1.0
1.1
—
—
—
0
0
27
166
1.63
1.61
3.1
3.3
1108.44
1012.11
u/ml
0.08
27
166
8
32
2.50
1.59
1.1
1.0
—
—
—
0
0
10
44
2.28
1.55
1.2
1.0
—
—
—
0
0
287
2511
1.16
1.55
1.2
1.2
155.66
145.76
iu/ml
0.18
113
989
23
137
1.68
1.55
2.2
1.7
1.72
1.19
nmol/l
0.78
17
112
36
240
1.51
1.54
2.9
2.9
0.25
0.23
e9/l
0.22
31
204
5
15
3.34
1.52
3.0
2.2
—
—
—
0
0
90
704
1.29
1.51
1.8
2.4
483.46
346.29
ug/l
0.23
82
654
507
5563
0.90
1.50
3.3
3.3
1.02
1.02
kg/l
1.96
79
739
103
821
1.26
1.49
1.0
1.1
—
—
—
0
0
901
8434
1.09
1.49
2.0
1.9
—
—
—
0
0
13
65
2.00
1.48
1.2
1.2
—
—
—
0
0
307
2710
1.15
1.47
2.5
2.3
13.51
13.45
nmol/l
0.05
285
2509
299
2635
1.15
1.47
1.2
1.2
—
—
—
0
0
244
2119
1.16
1.47
7.7
8.2
5.16
5.09
kpa
0.60
233
2033
244
2119
1.16
1.47
7.7
8.2
12.87
13.15
kpa
0.40
235
2036
49
352
1.40
1.45
2.2
2.7
7.07
7.20
mmol/l
0.12
49
345
20
117
1.71
1.44
1.2
1.2
—
—
—
0
0
119
969
1.24
1.44
1.1
1.1
—
—
—
0
0
38
261
1.46
1.43
1.1
1.1
278.21
276.67
mg/l
0.05
33
239
145
1208
1.21
1.41
1.5
1.7
—
—
—
0
0
53
388
1.37
1.41
1.7
1.4
—
—
—
0
0
7
29
2.42
1.39
1.4
1.1
—
—
—
0
0
59
441
1.34
1.39
1.2
1.2
—
—
—
0
0
243
2121
1.16
1.38
7.9
8.2
0.93
0.96
mmol/l
0.05
209
1683
119
975
1.23
1.37
1.1
1.1
5.79
2.62
u/ml
0.81
60
491
36
248
1.46
1.35
2.9
2.9
625.77
548.39
e6/l
0.35
31
207
9
42
2.15
1.33
1.1
1.2
3.11
3.29
%
—
9
34
46
333
1.39
1.32
2.8
3.4
—
—
—
0
0
81
640
1.27
1.30
1.4
1.5
—
—
—
0
0
22
343
0.64
1.30
1.2
1.4
—
—
—
0
0
212
1843
1.16
1.29
1.1
1.1
—
—
—
0
0
23
353
0.65
1.27
19.1
12.8
890.04
832.04
nmol/l
0.24
23
340
51
380
1.35
1.25
2.2
2.6
1.30
1.45
mmol/l
0.97
51
370
24
362
0.66
1.23
28.0
18.5
1530.08
4041.92
nmol/l
0.47
24
350
169
1450
1.17
1.22
1.4
1.3
195.67
225.49
miu/ml
0.65
82
704
229
2011
1.15
1.22
1.4
1.3
53.99
40.75
au/ml
—
9
115
18
108
1.67
1.22
3.3
2.5
303.64
204.83
e6/l
0.23
11
58
6
26
2.31
1.18
1.0
1.1
—
—
—
0
0
88
712
1.24
1.18
1.6
1.5
—
—
—
0
0
74
587
1.27
1.17
1.4
1.2
—
—
—
0
0
97
796
1.22
1.15
2.1
2.0
4.71
4.43
iu/l
0.09
41
296
33
232
1.43
1.15
4.7
5.9
12.05
7.07
mmol/l
0.59
27
196
19
118
1.61
1.14
1.6
1.4
40415.17
34500.93
e6/l
0.11
12
70
41
300
1.37
1.14
1.2
1.5
306.64
376.05
pmol/l
0.76
36
267
7
31
2.26
1.10
1.1
1.2
—
57.90
—
0
5
43
320
1.35
1.09
1.2
1.7
81.63
59.91
mu/l
0.26
36
289
894
8470
1.07
1.09
1.6
1.5
—
—
—
0
0
13
219
0.59
1.09
1.9
3.0
41.08
45.15
%
—
8
113
11
59
1.87
1.07
2.7
2.4
—
—
—
0
0
94
776
1.22
1.07
1.2
1.4
502.94
470.12
mg/l
0.28
88
745
35
253
1.39
1.06
1.1
1.1
—
—
—
0
0
58
736
0.78
1.06
4.2
4.9
—
—
—
0
0
30
211
1.43
1.06
2.7
3.1
39565.70
42350.83
ug/l
0.61
30
211
21
137
1.54
1.05
1.1
1.0
8.39
15.05
u/ml
1.09
14
89
56
436
1.29
1.05
2.9
3.2
38.85
56.68
mg/l
0.56
38
344
71
570
1.25
1.04
1.1
1.2
—
—
—
0
0
243
2170
1.13
1.04
2.5
2.3
14.11
22.44
au/ml
2.19
25
252
196
1726
1.14
1.04
1.1
1.1
274.00
214.22
titre
—
5
45
56
437
1.29
1.04
2.9
3.2
26.25
38.51
mg/l
0.97
38
345
9
47
1.92
1.02
1.1
1.0
—
—
—
0
0
73
591
1.24
1.01
1.1
1.1
—
—
—
0
0
7
35
2.00
1.00
1.4
2.1
—
—
—
0
0
29
206
1.41
0.98
1.1
1.2
—
—
—
0
0
25
173
1.45
0.97
1.6
1.6
28.35
24.37
umol/l
0.23
25
165
66
531
1.25
0.97
1.2
1.1
16274.91
1490.57
iu/ml
0.42
16
144
29
207
1.40
0.96
1.4
1.2
—
—
—
0
0
22
150
1.47
0.92
1.5
2.2
—
—
—
0
0
9
52
1.73
0.92
1.0
1.2
—
—
—
0
0
44
339
1.30
0.92
1.5
1.5
—
—
—
0
0
19
126
1.51
0.91
1.4
1.5
1.00
5.23
u/field
1.68
19
93
17
110
1.55
0.90
1.0
1.1
—
—
—
0
0
80
664
1.21
0.90
1.6
1.5
109.74
105.30
u/ml
0.26
19
132
56
447
1.26
0.90
4.0
3.1
—
—
—
0
0
29
211
1.38
0.88
1.2
1.2
—
—
—
0
0
212
2357
0.89
0.87
2.5
2.2
—
—
—
0
0
31
229
1.36
0.86
1.0
1.0
—
—
—
0
0
366
3383
1.09
0.85
2.4
2.2
0.64
0.63
ug/l
0.06
174
1601
12
191
0.63
0.84
1.2
1.3
1487.40
94057.55
e6/l
—
5
140
8
45
1.78
0.84
1.1
10.6
—
—
—
0
0
8
45
1.78
0.84
1.0
1.0
—
—
—
0
0
104
892
1.17
0.83
1.4
1.3
171.82
81.51
titre
0.84
11
93
89
1044
0.85
0.80
1.3
1.3
—
—
—
0
0
33
250
1.32
0.80
1.0
1.1
—
—
—
0
0
46
365
1.26
0.79
3.4
2.1
—
—
—
0
0
38
294
1.30
0.79
1.1
1.5
63.17
68.51
mmol/l
0.20
24
244
8
48
1.67
0.78
2.0
1.7
—
—
—
0
0
118
1028
1.15
0.78
1.0
1.1
1.52
3.11
u/ml
1.53
18
163
65
538
1.21
0.78
1.3
1.2
4.38
4.06
u/ml
0.09
26
246
21
148
1.42
0.77
3.4
2.4
11.05
9.15
%
0.40
21
142
713
6786
1.06
0.77
6.4
7.0
—
—
—
0
0
549
5182
1.07
0.77
1.4
1.4
—
—
—
0
0
24
174
1.38
0.76
2.5
2.7
—
—
—
0
0
31
235
1.32
0.75
1.7
2.1
32.61
32.50
pg
0.05
31
235
39
493
0.79
0.75
1.3
1.7
4268.00
12897.37
e6/l
3.49
29
364
11
67
1.64
0.75
1.0
1.1
—
—
—
0
0
18
124
1.45
0.75
3.7
5.0
—
—
—
0
0
13
83
1.57
0.74
1.0
1.1
—
—
—
0
0
13
83
1.57
0.74
1.0
1.1
—
—
—
0
0
13
83
1.57
0.74
1.0
1.1
—
—
—
0
0
22
158
1.39
0.74
1.7
1.7
6.53
3.13
mg/l
0.96
22
149
101
875
1.16
0.73
1.1
1.1
2.85
2.26
u/ml
0.11
44
442
54
442
1.23
0.73
2.9
2.1
135.79
133.86
g/l
0.21
43
327
437
4101
1.07
0.73
3.5
3.2
483.45
468.84
ng/l
0.02
267
2519
7
39
1.80
0.72
1.7
3.5
—
—
—
0
0
11
68
1.62
0.71
1.3
1.7
—
—
—
0
0
86
738
1.17
0.71
1.1
1.1
3.68
3.92
u/ml
0.06
37
361
26
194
1.34
0.71
1.0
1.1
1485.35
1534.95
miu/ml
0.08
26
194
9
57
1.58
0.71
1.9
1.3
—
—
—
0
0
16
109
1.47
0.70
1.7
1.4
—
—
—
0
0
202
2219
0.90
0.70
3.4
2.4
—
—
—
0
0
63
527
1.20
0.70
2.4
2.1
—
—
—
0
0
385
3605
1.08
0.69
3.1
2.6
3.53
3.10
e6/l
0.27
212
1821
42
337
1.25
0.69
1.1
1.7
—
36.50
—
0
18
36
284
1.27
0.68
1.1
1.1
—
—
—
0
0
23
170
1.36
0.67
3.3
3.0
0.77
0.86
nmol/l
0.45
15
131
31
240
1.29
0.67
1.1
1.0
—
—
—
0
0
31
241
1.29
0.65
1.5
1.2
140.00
217.88
titre
—
5
52
26
197
1.32
0.65
1.8
1.6
5.92
6.54
mmol/l
0.84
19
142
30
233
1.29
0.64
1.9
1.6
52.61
54.62
%
0.11
23
152
79
681
1.16
0.64
1.1
1.1
3.28
5.54
u/ml
0.62
32
276
5
29
1.73
0.64
1.0
1.0
0.13
1.10
u/ml
—
5
14
44
359
1.23
0.63
1.3
1.3
—
45.89
—
0
22
18
129
1.40
0.63
1.0
1.1
—
—
—
0
0
13
87
1.50
0.63
1.2
1.1
—
—
—
0
0
21
155
1.36
0.63
1.2
1.3
—
—
—
0
0
18
130
1.39
0.61
1.2
1.1
—
—
—
0
0
83
722
1.15
0.60
1.3
1.4
17.54
21.43
u/l
0.75
68
610
0
21
0.00
0.60
0.0
1.0
—
0.03
—
0
10
63
537
1.18
0.59
1.8
2.3
—
—
—
0
0
20
148
1.35
0.59
1.1
1.1
—
—
—
0
0
8
52
1.54
0.59
1.3
1.5
—
—
—
0
0
168
1836
0.91
0.56
3.5
2.4
—
—
—
0
0
222
2393
0.92
0.55
3.4
2.3
—
—
—
0
0
389
3680
1.06
0.55
2.7
2.6
2.41
2.42
mmol/l
0.14
336
3220
99
880
1.13
0.55
1.1
1.1
—
—
—
0
0
97
862
1.13
0.54
1.0
1.1
0.56
1.32
u/ml
1.69
43
392
9
61
1.48
0.53
1.1
1.1
—
—
—
0
0
25
196
1.28
0.52
1.2
1.1
—
—
—
0
0
57
489
1.17
0.52
3.7
3.2
37.59
34.87
umol/l
0.33
49
461
6
40
1.50
0.51
1.0
1.1
37.67
32.80
%
—
6
35
102
913
1.12
0.51
1.1
1.1
8.56
6.72
u/ml
0.36
58
523
339
3203
1.06
0.51
1.4
1.5
—
—
—
0
0
19
144
1.32
0.50
2.8
3.3
—
—
—
0
0
223
2389
0.93
0.49
3.2
2.2
—
—
—
0
0
84
746
1.13
0.49
1.6
1.4
0.59
0.46
nmol/l
0.20
66
631
31
253
1.23
0.48
1.7
1.6
286.08
284.52
mosm/kgh2o
0.26
25
191
86
766
1.13
0.48
1.4
1.3
273.14
255.27
u/ml
0.20
61
499
28
226
1.24
0.48
1.0
1.1
13.66
7.84
iu/ml
—
8
56
222
2074
1.08
0.47
2.3
2.3
3305.70
4738.62
u/l
0.44
80
766
17
221
0.77
0.46
8.9
6.7
—
—
—
0
0
17
221
0.77
0.46
4.5
3.4
—
—
—
0
0
13
94
1.38
0.46
3.1
2.8
—
—
—
0
0
5
84
0.59
0.45
1.6
1.2
—
—
—
0
0
157
1450
1.09
0.45
2.5
2.4
—
—
—
0
0
25
201
1.25
0.45
3.2
4.0
12.88
11.31
%
1.02
25
201
57
497
1.15
0.44
2.9
2.4
87.30
153.68
ug/min
0.81
32
322
180
1675
1.08
0.43
3.8
4.1
8.04
41.71
ug/l
0.91
122
1269
71
630
1.13
0.43
1.1
1.1
—
—
—
0
0
222
2365
0.93
0.43
3.2
2.3
—
—
—
0
0
40
340
1.18
0.43
1.1
1.2
36.25
37.89
mg/l
0.14
34
278
5
31
1.61
0.43
1.0
1.0
—
—
—
0
0
33
393
0.84
0.43
1.5
1.3
180.35
202.41
pmol/l
0.34
33
393
6
93
0.64
0.42
1.8
1.8
—
—
—
0
0
16
122
1.31
0.42
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
0.15
—
0
7
0
16
0.00
0.41
0.0
1.9
—
—
—
0
0
25
204
1.23
0.40
2.1
2.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
27
223
1.21
0.39
1.1
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
69
617
1.12
0.39
1.0
1.1
0.23
0.57
u/ml
0.47
16
168
102
1113
0.91
0.38
1.3
1.4
—
—
—
0
0
9
68
1.32
0.37
1.3
1.4
—
—
—
0
0
5
37
1.35
0.37
1.6
3.4
31.60
48.83
umol/l
—
5
29
18
143
1.26
0.37
1.9
1.7
—
—
—
0
0
26
216
1.21
0.36
1.3
1.4
—
—
—
0
0
102
1110
0.92
0.36
1.3
1.4
—
—
—
0
0
24
198
1.21
0.36
1.2
1.2
—
—
—
0
0
38
329
1.16
0.35
1.1
1.1
270.53
231.34
mg/l
0.69
32
289
18
145
1.24
0.33
1.4
1.5
136.48
136.89
nmol/l
0.02
18
145
6
46
1.30
0.33
1.2
1.1
—
—
—
0
0
6
47
1.28
0.32
2.5
1.9
—
—
—
0
0
26
220
1.18
0.31
1.0
1.2
—
—
—
0
0
21
174
1.21
0.31
1.2
1.2
—
—
—
0
0
107
1151
0.93
0.31
1.3
1.5
—
—
—
0
0
159
1499
1.06
0.30
1.1
1.1
—
—
—
0
0
29
335
0.86
0.29
4.4
4.7
34.97
86.46
u/ml
—
10
100
10
130
0.77
0.29
2.9
3.1
—
—
—
0
0
152
1610
0.94
0.29
1.4
1.4
—
—
—
0
0
63
573
1.10
0.29
1.4
1.5
—
—
—
0
0
8
110
0.73
0.28
1.0
1.6
—
—
—
0
0
96
1031
0.93
0.27
4.9
3.3
—
—
—
0
0
55
500
1.10
0.26
3.2
3.0
25.07
24.22
mg/l
0.06
36
311
492
4786
1.03
0.26
1.7
1.7
—
—
—
0
0
26
299
0.87
0.26
1.3
3.0
—
—
—
0
0
397
3850
1.04
0.25
3.1
2.4
0.88
1.10
e6/l
0.44
224
2058
17
142
1.20
0.24
1.2
1.3
181.18
168.30
mmol/24h
0.32
17
142
26
228
1.14
0.22
1.1
1.1
—
—
—
0
0
7
92
0.76
0.22
2.4
2.3
—
—
—
0
0
54
496
1.09
0.22
5.6
6.5
384.54
380.02
umol/l
0.07
41
441
15
125
1.20
0.22
1.3
1.5
—
—
—
0
0
17
199
0.85
0.21
2.1
1.5
—
—
—
0
0
73
681
1.07
0.21
1.5
1.5
292.86
2250.11
e6/l
1.19
58
557
0
11
0.00
0.21
0.0
1.4
—
2110.18
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
55
595
0.92
0.21
1.4
1.3
—
—
—
0
0
73
682
1.07
0.21
1.5
1.5
13.37
25.66
e6/l
0.74
57
527
33
297
1.11
0.20
2.2
1.7
—
—
—
0
0
6
51
1.18
0.19
1.0
1.1
3.63
6.01
nmol/l
—
6
46
139
1449
0.96
0.18
1.8
2.1
6.54
6.44
ug/l
0.02
120
1296
19
216
0.88
0.17
1.0
1.0
—
—
—
0
0
256
2490
1.03
0.16
2.8
2.7
37.46
39.98
u/l
0.20
224
2178
8
72
1.11
0.16
1.0
1.2
1.51
0.62
u/ml
—
8
72
120
1153
1.04
0.15
4.8
5.8
—
—
—
0
0
9
81
1.11
0.15
1.1
1.1
—
—
—
0
0
11
129
0.85
0.14
1.0
1.5
—
—
—
0
0
7
87
0.80
0.14
2.6
2.3
—
—
—
0
0
51
479
1.07
0.14
3.4
3.8
—
—
—
0
0
8
96
0.83
0.13
1.8
2.6
22.21
16.75
umol/l
—
8
96
41
384
1.07
0.12
1.6
1.5
—
—
—
0
0
65
682
0.95
0.12
1.2
1.3
2.86
2.94
ug/l
0.06
60
625
44
467
0.94
0.12
1.5
1.4
6.79
6.92
mmol/l
0.09
37
429
14
158
0.89
0.12
1.8
2.5
9.70
9.84
mg/l
—
9
128
5
61
0.82
0.08
1.4
1.5
—
—
—
0
0
5
62
0.81
0.08
2.0
1.8
1.72
1.39
mg/l
—
5
53
16
146
1.10
0.08
1.3
1.2
—
—
—
0
0
6
70
0.86
0.07
5.0
2.9
—
—
—
0
0
6
72
0.83
0.07
1.0
2.0
—
—
—
0
0
6
75
0.80
0.07
2.3
1.9
—
—
—
0
0
18
194
0.93
0.07
1.2
1.3
—
—
—
0
0
7
84
0.83
0.07
1.0
1.3
—
—
—
0
0
559
5637
0.99
0.07
3.1
3.2
—
—
—
0
0
142
1446
0.98
0.06
1.9
2.6
62.77
36.49
u/ml
0.58
137
1399
65
632
1.03
0.06
3.8
3.8
56.79
331.83
u/ml
1.32
56
540
32
307
1.04
0.05
1.0
1.1
0.24
1.63
u/ml
1.15
11
98
53
545
0.97
0.05
1.6
1.7
—
—
—
0
0
10
92
1.09
0.03
1.8
1.5
2.40
4.12
%
—
5
25
22
229
0.96
0.02
1.1
1.1
—
—
—
0
0
24
249
0.96
0.02
1.2
1.2
1.63
1.52
g/l
1.19
24
249
28
271
1.03
0.02
1.4
1.6
—
—
—
0
0
32
329
0.97
0.02
1.7
1.6
—
—
—
0
0
86
870
0.99
0.02
1.3
1.3
—
—
—
0
0
33
338
0.98
0.01
1.2
1.2
21.54
35.26
u/l
0.53
27
290
169
1699
0.99
0.01
3.6
3.4
—
—
—
0
0
12
114
1.05
0.00
1.4
1.6
12.52
14.64
pmol/l
0.97
12
96
18
186
0.97
0.00
7.0
7.3
—
—
—
0
0
30
306
0.98
0.00
1.0
1.0
0.32
1.53
u/ml
—
6
65
134
1334
1.00
0.00
2.4
2.7
156.45
132.32
ng/l
0.29
119
1159
289
2896
1.00
0.00
1.4
1.3
—
—
—
0
0
13
128
1.02
0.00
1.5
1.4
—
—
—
0
0
14
135
1.04
0.00
2.3
2.7
304.50
169.08
umol/l
—
8
65
18
185
0.97
0.00
2.2
1.5
24.17
33.87
%
0.55
12
118
63
628
1.00
0.00
1.0
1.1
3.24
3.03
u/ml
0.06
31
354
132
1315
1.00
0.00
1.3
1.4
—
—
—
0
0
156
1565
1.00
0.00
5.4
3.5
—
—
—
0
0
77
771
1.00
0.00
1.7
1.4
—
—
—
0
0
32
316
1.01
0.00
1.0
1.1
0.41
0.89
u/ml
—
10
72
30
296
1.01
0.00
1.3
1.8
—
—
—
0
0
13
126
1.03
0.00
1.5
1.2
—
—
—
0
0
21
206
1.02
0.00
3.2
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
53
0.94
0.00
1.2
1.5
17.86
12.41
g/l
—
5
39
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
37.04
—
0
8
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
171.60
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
155.32
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
1291.86
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.2
—
—
—
0
0
65
650
1.00
-0.00
1.1
1.1
—
—
—
0
0
5
57
0.88
-0.00
4.4
1.8
1.12
1.18
mmol/l
—
5
52
6
69
0.87
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
-0.00
2.9
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_EUSTSALP and mortality.

Females

Parameter HR [95% CI] p-value
H8_EUSTSALP 0.882 [0.71, 1.09] 0.255
Birth year 0.993 [0.98, 1.0] 0.125

During the follow-up period (1.1.1998 — 31.12.2019), 109 out of 3289 females with H8_EUSTSALP died.

Males

Parameter HR [95% CI] p-value
H8_EUSTSALP 0.873 [0.69, 1.1] 0.243
Birth year 0.99 [0.98, 1.0] 0.032

During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 2993 males with H8_EUSTSALP died.

Mortality risk

Mortality risk for people of age

years, who have H8_EUSTSALP.

N-year risk Females Males
1 0.092% 0.177%
5 0.469% 1.006%
10 1.221% 2.684%
15 2.401% 5.315%
20 4.328% 9.138%

Relationships between endpoints

Index endpoint: H8_EUSTSALP – Eustachian salpingitis and obstruction

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data