Eustachian salpingitis and obstruction

H8_EUSTSALP

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H68
  • Hospital discharge: ICD-9 3816
  • Hospital discharge: ICD-8 3840[0-2]
  • Cause of death: ICD-10 H68
  • Cause of death: ICD-9 3816
  • Cause of death: ICD-8 3840[0-2]

2 out of 7 registries used, show all original rules.

3449

4. Check minimum number of events

None

3449

5. Include endpoints

None

3449

6. Filter based on genotype QC (FinnGen only)

3449

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31754 13543 18131
Only index persons 30023 12880 17143
Unadjusted period prevalence (%)
Whole population 0.45 0.39 0.51
Only index persons 0.58 0.47 0.65
Median age at first event (years)
Whole population 5.11 5.81 4.58
Only index persons 5.10 5.83 4.54

-FinnGen-

Key figures

All Female Male
Number of individuals 3449 1936 1513
Unadjusted period prevalence (%) 0.66 0.66 0.67
Median age at first event (years) 6.49 6.85 6.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3120
Matched controls
31201
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
38400
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) acuta
+∞
323.0
434
*
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
21.0
323.0
1748
1789
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
291.3
323.0
338
13
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
148.6
323.0
830
76
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
323.0
368
*
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
323.0
1177
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
323.0
704
*
4122
FHL
Tympanostomy (tympanic tube)
126.0
287.2
307
27
H65.3
ICD-10 Finland
Chronic mucoid otitis media
192.2
286.9
296
17
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
353.2
227.1
227
7
DGW00
NOMESCO Finland
Dilatation of eustachian tube
2043.5
210.7
202
*
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
202.3
192
*
UDC00
NOMESCO Finland
Ear microscopy
7.7
183.0
455
673
H66.0
ICD-10 Finland
Acute suppurative otitis media
7.4
178.4
457
706
H65.2
ICD-10 Finland
Chronic serous otitis media
238.6
176.3
180
8
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
55.6
170.3
203
39
DFF00
NOMESCO Finland
Pure tone audiometry
5.9
128.1
385
723
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
121.7
116
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.2
120.1
514
1407
H66.9
ICD-10 Finland
Otitis media, unspecified
5.6
110.5
344
670
DC1AD
NOMESCO Finland
Temporalbone CT
32.5
107.6
143
46
DCD00
NOMESCO Finland
Myringoplasty
+∞
103.7
99
*
H71
ICD-10 Finland
Cholesteatoma of middle ear
255.5
97.2
99
*
H68.0
ICD-10 Finland
Eustachian salpingitis
84.5
94.7
106
13
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
86.9
83
*
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
41.3
76.5
96
24
4451
FHL
Guitar cutting
4.7
64.1
229
512
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
62.6
1686
11987
R01AD08
ATC
fluticasone; nasal
2.0
61.1
1051
6312
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
64.1
59.6
69
11
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
15.3
56.2
94
63
H65.0
ICD-10 Finland
Acute serous otitis media
11.6
56.0
106
94
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.4
53.1
282
895
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
6.1
50.1
141
239
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.0
49.8
817
4744
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
49.1
47
*
4141
FHL
Myringoplasty (also for reasons other than inflammation)
238.5
46.1
47
*
R01AD09
ATC
mometasone; nasal
1.7
45.1
1507
10997
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
121.8
44.9
48
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
43.8
42
*
H92.0
ICD-10 Finland
Otalgia
3.3
42.7
228
724
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
35.9
41.3
53
15
TDA90
NOMESCO Finland
Removal wax from ear
13.4
40.4
71
54
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.7
39.0
278
1072
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
25.6
38.0
53
21
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
37.6
36
*
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
8.9
36.0
78
90
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
34.4
33
*
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
19.6
34.4
52
27
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
29.2
34.2
46
16
J01FA10
ATC
azithromycin; systemic
1.6
33.4
1818
14611
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
33.4
32
*
H01
ICPC
Ear pain/earache
2.2
33.0
357
1709
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
32.3
31
*
H66
ICD-10 Finland
Suppurative and unspecified otitis media
4.5
32.1
118
272
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
31.3
30
*
J01CA04
ATC
amoxicillin; systemic
1.7
30.7
2476
21734
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
9.9
30.1
61
63
H02AB06
ATC
prednisolone; systemic
1.6
29.3
1214
9017
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
5.4
28.8
88
166
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
28.2
906
6297
R01AD12
ATC
fluticasone furoate; nasal
1.6
27.5
1024
7381
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.4
27.5
254
1126
4452
FHL
Tonsil surgery
2.8
27.1
178
651
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
27.1
26
*
J01DA01
ATC
[U] cefalexin; systemic
1.5
26.8
1810
14918
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.4
25.6
225
972
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.0
25.0
148
504
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
24.0
23
*
S02CA02
ATC
flumetasone and antiinfectives; otic
2.9
23.7
152
548
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
8.4
23.6
52
63
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
54.4
23.1
27
5
H69.0
ICD-10 Finland
Patulous Eustachian tube
20.2
23.0
34
17
EMB30
NOMESCO Finland
Adenotomy
5.4
23.0
70
133
H29
ICPC
Ear symptom/complaint other
2.2
22.9
237
1108
H60.8
ICD-10 Finland
Other otitis externa
3.7
22.5
100
276
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
22.5
688
4676
DCD10
NOMESCO Finland
Tympanoplasty
115.8
21.6
23
*
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.3
21.0
106
325
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
20.9
901
6621
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
7.1
20.8
51
73
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
9.4
20.5
42
45
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
20.2
20.4
30
15
ZXA10
NOMESCO Finland
Bilateral
1.8
20.0
406
2448
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.2
19.9
105
333
DEB30
NOMESCO Finland
Radical mastoidectomy
+∞
19.8
19
*
50300
ICD-8 Finland
Chronic sinusitis, Maxillaris cum empyemate
11.0
19.6
37
34
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.3
19.4
180
799
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
22.7
19.0
27
12
J01FA09
ATC
clarithromycin; systemic
1.5
18.8
889
6634
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
18.8
18
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.4
18.7
92
277
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
18.7
280
1525
1450
FHL
Otomicroscopy
9.0
18.6
39
44
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
38.6
18.5
23
6
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.0
18.4
73
184
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
36.9
17.6
22
6
J01DB01
ATC
cefalexin; oral
1.5
17.5
2417
21901
J01DA08
ATC
[U] cefaclor; oral
1.8
17.4
292
1650
DFF15
NOMESCO Finland
Speech audiometry
3.5
17.4
83
245
H13
ICPC
Plugged feeling ear
1.8
17.3
325
1910
J01AA02
ATC
doxycycline; systemic
1.4
17.0
2124
18817
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
16.7
16
*
R03AC02
ATC
salbutamol; inhalant
1.4
16.7
1455
12100
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
2.4
16.5
144
622
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
18.0
16.4
25
14
SPAT1043
SPAT
Audiometry
2.3
15.9
156
710
J01DA06
ATC
[U] cefuroxime; systemic
1.7
15.7
374
2358
H71
ICPC
Acute otitis media/myringitis
4.5
15.6
55
124
J32.4
ICD-10 Finland
Chronic pansinusitis
4.0
15.5
61
153
H60.3
ICD-10 Finland
Other infective otitis externa
3.6
15.5
70
198
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.3
15.5
143
634
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.0
15.5
91
313
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.8
15.4
99
359
H02AB04
ATC
methylprednisolone; systemic
1.7
15.4
339
2088
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
15.3
573
4042
H02
ICPC
Hearing complaint
2.1
15.3
171
829
UDM02
NOMESCO Finland
Sinoscopy
3.3
15.2
78
244
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
3.2
14.9
78
248
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
56.9
14.8
17
*
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
14.6
14
*
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
80.5
14.6
16
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
14.3
119
503
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.5
13.7
64
187
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
75.5
13.6
15
*
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
13.5
13
*
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
+∞
13.5
13
*
R06.0
ICD-10 Finland
Dyspnoea
1.5
13.5
485
3379
4364
FHL
Pharyngeal tongue plastic
25.8
13.4
18
7
Q35.1
ICD-10 Finland
Cleft hard palate
21.2
13.3
19
9
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.4
13.3
659
4907
N07CA01
ATC
betahistine; oral
2.2
13.2
135
628
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
2.7
13.1
91
348
48509
ICD-8 Finland
Bronchopneumonia, unspecified
3.6
13.1
59
168
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
13.0
240
1399
H60.4
ICD-10 Finland
Cholesteatoma of external ear
14.1
12.7
21
15
H61.2
ICD-10 Finland
Impacted cerumen
2.3
12.7
119
535
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
12.6
903
7170
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
+∞
12.5
12
*
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
37.7
12.2
15
*
A02BC02
ATC
pantoprazole; systemic
1.3
12.1
1554
13450
R06AE07
ATC
cetirizine; oral
1.3
12.0
1239
10389
R42
ICD-10 Finland
Dizziness and giddiness
1.5
12.0
400
2738
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.7
11.9
80
302
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
4.7
11.8
39
84
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
11.7
390
2667
48609
ICD-8 Finland
Pneumonia, unspecified
3.0
11.7
67
227
4129
FHL
Other measure in this category
30.1
11.6
15
5
R01AD11
ATC
triamcinolone; nasal
1.7
11.6
227
1348
H61.8
ICD-10 Finland
Other specified disorders of external ear
5.1
11.5
35
69
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.6
11.5
272
1707
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
11.5
11
*
H73.1
ICD-10 Finland
Chronic myringitis
+∞
11.5
11
*
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
11.5
212
1239
1451
FHL
Otomicroscopy and paper place
120.4
11.4
12
*
4224
FHL
Endonasal anthrostomy
4.5
11.4
39
87
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
11.4
644
4902
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.5
11.3
52
152
A02BC05
ATC
esomeprazole; systemic
1.3
11.3
938
7597
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
11.2
946
7682
4740A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Chronic tonsillitis
2.1
11.1
129
638
H60
ICD-10 Finland
Otitis externa
2.0
10.9
139
713
J01FF01
ATC
clindamycin; systemic
1.4
10.9
656
5042
G47.3
ICD-10 Finland
Sleep apnoea
1.4
10.9
486
3534
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
10.8
343
2322
J35.2
ICD-10 Finland
Hypertrophy of adenoids
3.6
10.8
47
132
J01DC02
ATC
cefuroxime; systemic
1.9
10.6
161
883
D82
ICPC
Teeth/gum disease
1.3
10.5
995
8196
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
10.4
10
*
38200
ICD-8 Finland
Acute / Acute otitis media with mastoiditis
+∞
10.4
10
*
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
+∞
10.4
10
*
J34.2
ICD-10 Finland
Deviated nasal septum
1.9
10.4
155
844
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
16.1
10.3
16
10
H72
ICD-10 Finland
Perforation of tympanic membrane
32.6
10.3
13
*
H69.9
ICD-10 Finland
Eustachian tube disorder, unspecified
8.2
10.3
22
27
74920
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis unilateralis
18.8
10.3
15
8
4741A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PALATINAE]
4.2
10.1
37
89
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
10.1
238
1494
4221
FHL
Polyp removal from the nasal cavity, sinus puncture or irrigation, or biopsy under general anesthesia or operating room
4.0
10.1
39
99
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
10.0
850
6882
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
10.0
1472
12839
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
10.0
185
1085
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
3.4
10.0
47
141
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
9.9
137
725
50709
ICD-8 Finland
Hay fever, Unspecified
6.7
9.9
24
36
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.8
1013
8426
ZFX00
NOMESCO Finland
Use of balloon dilatation
20.1
9.8
14
7
N02BE01
ATC
paracetamol; systemic, rectal
1.3
9.8
2303
21313
R01AD05
ATC
budesonide; nasal
1.7
9.7
203
1229
H04
ICPC
Ear discharge
2.7
9.7
66
252
M01AE02
ATC
naproxen; oral, rectal
1.3
9.7
1528
13423
J01MA12
ATC
levofloxacin; systemic
1.5
9.7
345
2395
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.6
494
3684
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
9.6
1541
13561
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
2.0
9.6
116
586
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.4
9.4
75
313
R01AD01
ATC
beclometasone; nasal
1.4
9.4
410
2961
4151
FHL
Reoperation for chronic otitis media
100.3
9.4
10
*
R06AX27
ATC
desloratadine; oral
1.3
9.4
801
6477
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
9.4
9
*
H74.0
ICD-10 Finland
Tympanosclerosis
+∞
9.4
9
*
7490B
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS INCOMPLETA]
+∞
9.4
9
*
R5120
NOMESCO Finland
Preparation of an aid
3.4
9.2
43
129
WX723
NOMESCO Finland
CPAP therapy
2.1
9.0
96
460
SPAT1263
SPAT
Sampling
1.3
8.9
1047
8838
H02AB07
ATC
prednisone; oral
1.5
8.8
298
2043
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
8.8
204
1277
R03AK08
ATC
formoterol and beclometasone; inhalant
2.2
8.8
84
382
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
50.1
8.7
10
*
R03DC03
ATC
montelukast; oral
1.4
8.6
413
3035
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
8.6
660
5245
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
8.6
475
3580
S02AA03
ATC
boric acid; otic
5.2
8.6
25
48
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
8.6
424
3135
ZXA00
NOMESCO Finland
Right side
1.4
8.6
484
3667
J02AC01
ATC
fluconazole; systemic
1.3
8.5
1078
9170
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.5
1179
10140
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
20.1
8.5
12
6
74929
ICD-8 Finland
Cleft palate and cleft lip, Unspecified
90.3
8.4
9
*
J01FA01
ATC
erythromycin; systemic
1.4
8.4
398
2921
J01FA15
ATC
telithromycin; oral
1.5
8.4
252
1684
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
12.8
8.4
14
11
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
+∞
8.3
8
*
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
8.3
8
*
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
8.3
569
4442
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
8.3
947
7943
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
8.3
119
643
L15
ICPC
Knee symptom/complaint
1.4
8.2
376
2744
SPAT1153
SPAT
Removal of sutures
1.3
8.1
599
4734
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.1
8.0
84
399
A02BC01
ATC
omeprazole; systemic
1.3
8.0
546
4256
M03BX02
ATC
tizanidine; oral
1.2
8.0
1782
16147
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
7.9
686
5544
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.3
7.9
70
308
J01FA06
ATC
roxithromycin; oral
1.3
7.9
988
8378
EMB10
NOMESCO Finland
Tonsillectomy
1.6
7.8
214
1396
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.8
7.8
119
658
DPA30
NOMESCO Finland
Sphenotomy
4.8
7.7
24
50
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
4.4
7.7
26
59
R51.80
ICD-10 Finland
Headache
1.4
7.7
392
2912
DHB50
NOMESCO Finland
Turbinoplasty
2.0
7.7
89
444
UJF32
NOMESCO Finland
Coloscopy
1.4
7.7
451
3432
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
7.7
380
2810
S02AA30
ATC
antiinfectives, combinations; otic
2.0
7.6
91
460
H65
ICD-10 Finland
Nonsuppurative otitis media
3.7
7.6
31
84
WX402
NOMESCO Finland
General anaesthesia
1.4
7.6
396
2956
M01AH05
ATC
etoricoxib; oral
1.2
7.6
1544
13810
H73.0
ICD-10 Finland
Acute myringitis
8.0
7.6
16
20
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
7.6
2066
19081
H72
ICPC
Serous otitis media
25.1
7.6
10
*
SPAT1211
SPAT
Application of soft bandage
1.6
7.5
172
1074
J01MA02
ATC
ciprofloxacin; systemic
1.3
7.5
807
6699
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
3.8
7.5
30
80
J20
ICD-10 Finland
Acute bronchitis
1.6
7.5
210
1380
R03BA05
ATC
fluticasone; inhalant
1.4
7.4
420
3182
ZZG00
NOMESCO Finland
Graft of cartilage
13.4
7.4
12
9
WX780
NOMESCO Finland
Remote monitoring CPAP
1.9
7.4
99
523
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
7.3
449
3442
RK520
NOMESCO Finland
NA
8.4
7.3
15
18
3816A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Obstruction of Eustachian tube
+∞
7.3
7
*
3851A
ICD-9 Finland
Other disorders of middle ear and mastoid, Adhesive middle ear disease
+∞
7.3
7
*
AA1AD
NOMESCO Finland
CT of head and brain
1.4
7.2
388
2910
N02AX02
ATC
tramadol; systemic, rectal
1.3
7.2
891
7528
DC1AI
NOMESCO Finland
Cone beam CT of ear
30.1
7.1
9
*
H03AA01
ATC
levothyroxine sodium; systemic
1.3
7.1
470
3643
WX002
NOMESCO Finland
Sedation and analgesia
1.4
7.1
355
2627
SPAT1262
SPAT
Handing over of treatment supplies
1.4
7.1
323
2351
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
6.6
7.1
17
26
SPAT1312
SPAT
General health counselling
1.3
7.1
731
6037
05209
ICD-8 Finland
Chickenpox, Unspecified
5.6
7.1
19
34
J33.8
ICD-10 Finland
Other polyp of sinus
2.5
7.0
51
206
WX110
NOMESCO Finland
Local anesthesy
1.2
7.0
1963
18092
R01BA01
ATC
phenylpropanolamine; oral
1.8
7.0
112
632
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
7.0
191
1251
R06AX13
ATC
loratadine; oral
1.3
6.9
426
3273
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
2.3
6.9
56
241
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.7
367
2760
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.6
208
1405
H93.1
ICD-10 Finland
Tinnitus
1.7
6.6
123
728
E0000UV
ATC
NA
1.2
6.6
949
8140
1290
FHL
Epipharyngoscopy
12.3
6.6
11
9
R96
ICPC
Asthma
1.6
6.6
159
1012
N03AX12
ATC
gabapentin; oral
1.4
6.5
302
2208
H92.1
ICD-10 Finland
Otorrhoea
10.0
6.5
12
12
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
3.6
6.5
27
76
R05FB02
ATC
cough suppressants and expectorants
1.3
6.4
761
6379
4362
FHL
Nozzle reconstruction
70.0
6.4
7
*
TDB00
NOMESCO Finland
Removal of foreign body from external auditory canal
70.0
6.4
7
*
E66.01
ICD-10 Finland
Obesity due to excess calories
1.5
6.4
203
1377
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
14.3
6.4
10
7
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.3
1810
16631
49099
ICD-8 Finland
Bronchitis, unspecified
2.8
6.3
38
139
WX320
NOMESCO Finland
Spinalanesthesy
1.3
6.3
439
3434
A02BA02
ATC
ranitidine; systemic
1.4
6.3
322
2395
R74
ICPC
Upper respiratory infection acute
1.2
6.3
848
7215
Q90.9
ICD-10 Finland
Down syndrome, unspecified
18.0
6.3
9
5
N03AX16
ATC
pregabalin; oral
1.3
6.3
463
3652
4161
FHL
Exploratory tympanotomy
+∞
6.3
6
*
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
+∞
6.3
6
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
6.2
505
4030
Q35.9
ICD-10 Finland
Cleft palate, unspecified
26.7
6.2
8
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
6.2
542
4372
R03CC02
ATC
salbutamol; systemic
1.7
6.2
117
697
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
6.1
269
1948
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.8
6.1
98
552
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.2
6.1
767
6470
DCA30
NOMESCO Finland
Exploration of middle ear
12.5
6.1
10
8
P01AB01
ATC
metronidazole; oral, rectal
1.2
6.0
943
8145

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
514
2950
1.87
34.11
2.0
1.6
—
—
—
0
0
834
5511
1.68
33.95
3.3
3.0
—
—
—
0
0
1150
8722
1.48
23.97
6.2
6.5
—
—
—
0
0
1047
7865
1.48
22.62
7.8
6.4
1.1
1.1
inr
0.01
397
2544
358
2235
1.67
17.17
3.5
3.2
—
—
—
0
0
283
1666
1.76
16.80
3.7
3.4
1.2
1.2
mmol/l
2.15
253
1466
1178
9428
1.38
16.68
5.8
5.7
1.2
1.2
mmol/l
0.92
1071
8703
1282
10552
1.34
14.65
6.3
6.3
1.2
1.2
mmol/l
0.50
1027
8988
1436
12036
1.33
14.44
9.3
8.4
0.0
0.0
e9/l
0.11
1180
9864
2192
19519
1.34
14.42
4.2
3.7
9.3
9.0
mm/h
0.68
2044
18434
108
479
2.30
14.32
3.5
3.3
2.3
2.1
mmol/l
0.31
79
287
121
563
2.19
14.30
3.3
3.5
7.4
7.4
ph
0.18
107
468
2001
17654
1.32
13.65
4.0
3.7
—
—
—
0
0
1476
12486
1.32
13.65
6.5
6.4
0.7
0.7
%
0.48
1383
11808
1519
12905
1.32
13.61
6.4
6.3
2.9
2.8
%
0.45
1423
12181
121
580
2.13
13.29
4.1
3.9
57.9
56.9
%
0.35
121
580
1599
13739
1.31
12.96
4.6
4.4
6.5
6.5
mmol/l
0.34
1471
12667
118
566
2.12
12.95
3.9
3.6
3.9
4.0
e9/l
0.14
118
566
2154
19280
1.31
12.81
7.3
6.9
73.4
73.6
u/l
0.08
2032
18354
1519
12982
1.30
12.73
6.6
6.5
8.2
8.3
%
0.47
1434
12342
1547
13254
1.30
12.73
6.1
6.1
56.6
56.5
%
0.24
1466
12586
1562
13444
1.30
12.24
6.5
6.2
29.1
29.3
%
0.39
1474
12733
987
8083
1.31
10.92
2.9
2.8
33.6
34.7
ng/l
0.04
505
4016
54
205
2.66
10.09
2.6
2.5
—
—
—
0
0
2986
28358
1.39
9.84
12.3
10.7
20.4
20.5
mg/l
0.05
2353
21676
380
2717
1.45
9.78
6.5
6.6
1.0
1.0
mmol/l
0.15
361
2574
570
4384
1.36
9.57
2.5
2.5
556.5
554.6
mosm/kgh2o
0.06
511
3747
410
2990
1.42
9.46
1.5
1.5
—
—
—
0
0
87
423
2.08
9.32
2.5
2.1
17.2
17.2
%
0.05
32
216
275
1864
1.52
9.24
3.4
3.7
—
—
—
0
0
1564
13763
1.25
9.23
6.2
6.2
0.6
0.6
e9/l
0.04
1379
12198
1567
13802
1.25
9.14
6.2
6.2
0.0
0.0
e9/l
0.26
1381
12204
1227
10518
1.26
9.06
1.9
1.9
—
—
—
0
0
1609
14233
1.24
8.96
6.2
6.2
2.0
2.0
e9/l
0.07
1451
12832
1131
9619
1.26
8.90
4.8
4.9
36.8
37.0
g/l
0.65
1057
9046
2485
26440
0.78
8.82
14.0
13.4
333.9
333.9
g/l
0.01
2465
26267
1405
12288
1.24
8.54
5.7
5.6
10.4
10.8
umol/l
0.81
1310
11676
1610
14300
1.24
8.45
6.5
6.5
0.2
0.2
e9/l
0.77
1447
12877
2336
21632
1.25
8.17
4.3
3.9
14.5
14.4
pmol/l
0.24
2155
20342
305
2166
1.45
8.13
3.2
2.5
10.2
10.5
g/l
0.94
278
2007
763
6252
1.28
8.02
4.4
4.0
7.4
7.4
ph
0.16
219
1225
274
1918
1.47
7.87
4.4
4.3
0.5
0.6
%
0.12
57
394
450
3443
1.35
7.73
3.6
3.6
0.8
0.8
mmol/l
0.30
429
3240
52
222
2.36
7.69
3.9
2.7
—
—
—
0
0
297
2123
1.44
7.65
1.3
1.3
304.3
225.2
u/ml
0.30
279
1987
241
1655
1.49
7.63
1.8
1.8
1.2
1.3
g/l
0.31
223
1560
2696
25464
1.27
7.50
4.9
4.5
1.7
2.0
mu/l
1.39
2504
24104
1721
15515
1.22
7.44
8.6
9.3
4.0
4.0
e9/l
0.02
1500
13747
896
7557
1.25
7.30
2.8
2.6
—
—
—
0
0
132
796
1.68
7.30
3.3
3.1
24.4
24.8
mmol/l
1.28
127
748
428
3287
1.34
7.16
1.9
1.7
1196.9
1158.1
nmol/l
0.35
316
2594
2563
24116
1.24
7.08
4.9
4.4
38.2
38.1
mmol/mol
0.22
2385
22965
51
225
2.29
7.03
1.5
1.2
2.9
0.6
u/ml
0.88
15
79
267
1903
1.44
6.99
4.5
4.5
0.0
0.5
%
0.98
62
414
2313
21543
1.22
6.97
3.2
3.0
43.5
41.8
u/l
0.48
2185
20722
189
1261
1.53
6.89
3.3
2.8
7.4
7.4
ph
0.04
25
164
898
7631
1.24
6.76
2.9
2.6
57.4
56.0
u/l
0.29
823
7171
276
1992
1.42
6.75
4.5
4.5
0.1
0.1
%
0.65
68
487
1208
10587
1.22
6.74
2.4
2.3
73.5
72.8
nmol/l
0.35
1115
9912
65
322
2.04
6.73
1.6
1.3
0.3
0.4
g/l
1.11
38
222
1420
12645
1.21
6.72
3.1
3.0
0.0
0.0
estimate
0.88
343
2394
65
323
2.03
6.67
1.6
1.3
3.1
3.1
g/l
0.05
38
223
65
323
2.03
6.67
1.6
1.3
6.1
6.8
g/l
1.19
37
224
189
1273
1.51
6.60
3.3
2.8
5.2
5.1
kpa
0.10
179
1195
65
325
2.02
6.57
1.6
1.4
—
—
—
0
0
975
8389
1.23
6.48
1.9
1.8
98.8
97.8
pmol/l
0.25
525
4631
1419
12668
1.20
6.46
4.3
4.2
0.0
0.0
estimate
0.24
350
2483
140
888
1.60
6.39
3.2
2.9
—
—
—
0
0
419
3274
1.32
6.21
1.2
1.2
—
—
—
0
0
2857
27335
1.26
6.13
12.6
10.9
139.6
139.6
mmol/l
0.02
2780
26643
354
2706
1.34
6.11
2.0
2.1
361.0
362.4
nmol/l
0.05
325
2510
1423
12754
1.20
6.10
3.1
3.1
0.0
0.0
estimate
0.30
333
2376
1482
13342
1.19
6.02
3.0
2.9
111.9
96.0
ug/l
0.66
1399
12708
2713
25824
1.24
6.00
3.9
3.5
5.8
5.7
mmol/l
0.53
2500
24317
283
2095
1.38
5.99
4.5
4.4
0.6
0.9
%
0.63
69
529
83
466
1.80
5.96
4.3
3.0
—
—
—
0
0
755
6382
1.23
5.86
1.7
1.6
1.5
1.4
mmol/l
0.49
622
5598
519
4213
1.27
5.74
1.3
1.4
432.2
554.8
titre
0.76
87
782
418
3307
1.30
5.66
2.0
2.0
—
—
—
0
0
2863
27457
1.25
5.65
12.9
11.0
3.9
3.9
mmol/l
0.86
2771
26699
1762
16171
1.18
5.57
3.9
3.6
1356.7
1089.1
e6/l
0.07
17
175
579
4790
1.25
5.44
1.3
1.3
7.8
9.1
u/ml
0.22
224
2113
762
6500
1.22
5.37
2.0
2.1
157.6
248.9
u/l
2.34
715
6202
547
4503
1.26
5.36
1.7
1.6
37104523.2
30182425.1
pmol/l
0.10
442
3956
358
2796
1.31
5.33
1.3
1.4
—
—
—
0
0
120
772
1.57
5.22
2.9
3.5
0.4
0.4
g/l
0.21
60
368
738
6302
1.22
5.12
1.5
1.4
2.2
2.3
g/l
1.44
477
4197
685
5814
1.22
5.05
2.2
2.2
2.7
2.8
mg/l
0.48
581
5052
718
6127
1.22
5.01
1.7
1.7
0.8
0.9
mg/l
0.33
523
4406
70
395
1.79
5.00
1.2
1.4
—
—
—
0
0
868
7553
1.20
4.93
2.3
2.2
—
—
—
0
0
59
318
1.87
4.89
1.3
1.3
—
—
—
0
0
664
5649
1.22
4.76
2.3
2.1
—
—
—
0
0
86
523
1.66
4.73
1.9
1.7
0.8
0.8
g/l
0.00
58
397
757
6542
1.20
4.60
3.3
3.4
0.0
0.0
estimate
2.03
343
2407
1361
12365
1.17
4.55
2.6
2.3
—
—
—
0
0
132
899
1.49
4.48
1.5
1.9
1.2
1.2
g/l
0.04
125
854
669
5734
1.21
4.42
4.7
4.2
10.3
9.7
mg/mmol
0.14
414
3846
145
1009
1.46
4.42
2.0
1.6
6.8
10.0
u/ml
—
6
42
3113
30306
1.28
4.39
9.7
8.6
29.0
28.4
u/l
0.68
3001
29588
622
5300
1.21
4.37
4.5
4.1
—
—
—
0
0
127
867
1.48
4.27
1.5
2.0
0.2
0.2
g/l
0.23
121
824
99
642
1.56
4.23
1.3
1.4
293.7
300.1
ug/g
0.09
51
326
640
5498
1.20
4.11
3.7
3.4
155.9
423.7
mg/l
1.59
402
3619
36
174
2.08
4.11
1.2
1.1
29.3
34.4
u/ml
—
9
17
721
6266
1.19
4.07
3.2
2.8
0.2
0.3
e6/l
0.80
559
4620
33
155
2.14
4.05
2.7
2.1
681.8
650.1
ml
0.11
24
109
141
995
1.43
4.02
1.2
1.2
—
—
—
0
0
11
28
3.94
3.97
1.2
1.1
—
—
—
0
0
16
53
3.03
3.96
1.2
1.2
—
—
—
0
0
16
53
3.03
3.96
1.2
1.2
—
—
—
0
0
16
53
3.03
3.96
1.2
1.2
—
—
—
0
0
1851
17322
1.15
3.91
3.1
2.9
—
—
—
0
0
10
24
4.18
3.88
1.2
1.2
—
—
—
0
0
110
747
1.49
3.83
2.2
2.0
1.4
1.4
g/l
0.14
89
650
3093
30158
1.25
3.81
11.7
9.7
—
—
—
0
0
139
989
1.42
3.81
1.5
1.7
—
—
—
0
0
533
4533
1.21
3.80
1.5
1.5
20.4
20.3
nmol/l
0.09
452
4050
551
4703
1.20
3.78
2.5
2.4
6.9
6.2
e6/l
0.46
499
4134
225
1732
1.32
3.77
9.5
8.6
7.9
7.9
mmol/l
0.05
217
1663
651
5643
1.19
3.77
2.4
2.5
—
—
—
0
0
428
3571
1.23
3.70
2.7
2.4
13.9
14.4
umol/l
0.65
398
3327
723
6335
1.18
3.69
2.4
2.3
1637.6
3600.4
umol/l
1.58
646
5720
829
7345
1.17
3.68
2.8
3.1
2.3
2.3
mmol/l
1.13
713
6676
31
148
2.10
3.68
1.0
1.1
8.1
12.7
u/ml
—
7
29
34
170
2.01
3.58
1.0
1.1
—
—
—
0
0
137
987
1.40
3.52
8.5
10.1
24.5
24.3
mmol/l
0.26
132
932
252
1992
1.29
3.49
2.9
2.4
0.2
0.2
g/l
0.61
242
1866
110
763
1.46
3.48
5.5
3.7
1.4
1.3
mg/l
1.19
105
724
1082
9816
1.15
3.47
2.9
2.9
—
5.9
—
0
8
125
890
1.42
3.44
3.2
3.0
—
—
—
0
0
27
126
2.15
3.41
2.9
2.2
513.6
506.7
min
0.14
20
99
2870
27845
1.18
3.35
3.9
3.6
1.4
1.4
mmol/l
3.03
2693
26580
39
210
1.87
3.35
1.1
1.1
1.1
1.0
ratio
0.48
18
79
388
3241
1.22
3.33
2.7
2.4
2.4
2.4
g/l
0.17
358
3019
359
2977
1.23
3.30
2.8
2.5
23.2
24.4
%
0.96
302
2597
66
416
1.60
3.26
3.2
3.7
—
—
—
0
0
774
6880
1.16
3.26
5.1
4.3
—
—
—
0
0
3308
32596
1.36
3.25
18.0
15.8
6.7
6.6
e9/l
1.13
3234
31903
776
6902
1.16
3.24
3.2
2.8
29.5
109.4
e6/l
2.20
609
5200
373
3113
1.22
3.23
1.2
1.2
—
—
—
0
0
245
1953
1.27
3.20
2.2
2.4
4.3
4.2
e9/l
0.31
198
1653
3308
32602
1.36
3.19
18.0
15.8
138.6
138.8
g/l
0.39
3260
32299
3306
32583
1.35
3.15
17.9
15.7
4.6
4.6
e12/l
0.16
3229
31920
3302
32538
1.35
3.15
18.0
15.7
260.0
258.8
e9/l
0.56
3233
31911
3305
32574
1.35
3.13
17.8
15.6
30.1
30.1
pg
0.10
3255
32280
712
6310
1.16
3.11
3.1
2.7
—
—
—
0
0
3305
32577
1.35
3.10
17.8
15.6
89.9
89.9
fl
0.12
3256
32284
2876
27955
1.17
3.06
3.9
3.6
4.8
4.8
mmol/l
1.75
2701
26750
56
345
1.63
3.05
1.6
1.6
—
—
—
0
0
490
4220
1.19
3.05
2.7
2.7
107.5
112.6
ug/g
0.19
387
3438
101
709
1.44
3.04
1.2
1.3
3.4
3.7
u/ml
—
7
72
2900
28220
1.17
2.98
12.1
11.4
40.8
41.1
%
0.77
2295
23641
102
721
1.43
2.97
1.2
1.3
14.6
10.0
u/ml
0.23
13
121
20
88
2.28
2.93
1.3
1.4
—
—
—
0
0
50
303
1.66
2.92
2.6
2.7
1.2
1.3
e9/l
0.37
32
172
919
8338
1.14
2.86
3.6
3.3
78.1
65.6
e6/l
0.20
655
5701
18
77
2.34
2.81
1.4
1.3
—
—
—
0
0
219
1752
1.27
2.81
1.5
1.6
255.8
292.1
mu/l
1.36
190
1596
2769
26880
1.15
2.80
3.5
3.3
1.4
1.3
mmol/l
1.35
2600
25610
242
1961
1.25
2.78
3.6
3.5
4.5
4.6
pmol/l
1.17
222
1769
802
7239
1.14
2.69
1.3
1.3
2.5
1.6
u/ml
0.70
230
2169
155
1200
1.31
2.59
1.9
1.7
—
—
—
0
0
751
6771
1.14
2.55
4.1
3.4
8.1
8.6
mmol/l
2.28
630
5933
2888
28170
1.15
2.52
4.1
3.8
2.9
2.9
mmol/l
0.74
2688
26797
216
1751
1.25
2.50
6.6
7.5
1.2
1.3
mmol/l
2.88
206
1685
298
2501
1.21
2.48
1.4
1.4
24.6
21.8
iu/l
0.71
249
2162
2547
24653
1.13
2.46
14.0
13.1
13.4
13.4
%
0.18
2493
24214
12
46
2.61
2.35
1.8
3.0
—
—
—
0
0
23
118
1.96
2.35
1.7
1.5
—
—
—
0
0
378
3260
1.18
2.34
1.4
1.4
—
—
—
0
0
36
214
1.69
2.32
4.8
3.8
—
—
—
0
0
1263
11807
1.11
2.28
3.9
3.7
—
—
—
0
0
130
1004
1.31
2.25
2.4
2.2
—
—
—
0
0
45
286
1.58
2.25
1.5
1.8
1.5
1.4
promille
0.19
32
224
453
5136
0.86
2.23
1.3
1.3
—
—
—
0
0
223
1843
1.22
2.20
1.3
1.2
—
—
—
0
0
208
1707
1.23
2.19
8.9
8.7
—
—
—
0
0
128
992
1.30
2.17
9.8
11.3
—
—
—
0
0
15
67
2.24
2.17
1.1
1.6
—
—
—
0
0
38
234
1.63
2.16
2.7
2.3
12.1
14.6
%
0.59
19
126
6
14
4.29
2.15
2.7
2.1
—
—
—
0
0
21
108
1.95
2.15
1.1
1.1
—
—
—
0
0
402
3514
1.16
2.12
1.9
1.9
—
—
—
0
0
22
116
1.90
2.10
1.5
1.4
—
—
—
0
0
58
398
1.47
2.07
1.2
1.1
1.4
1.4
g/l
0.51
52
366
210
2521
0.82
2.04
1.7
1.6
—
—
—
0
0
218
1814
1.22
2.03
4.4
4.2
1.7
1.8
mmol/l
0.29
181
1478
101
766
1.33
2.02
2.3
2.3
9.4
10.7
mg/l
1.00
93
725
696
6335
1.12
2.02
4.0
3.7
94.6
95.0
%
0.17
679
6163
38
239
1.60
2.01
2.7
2.3
73.9
73.7
%
0.03
38
231
25
140
1.79
2.00
1.5
1.3
—
—
—
0
0
91
681
1.35
1.99
2.3
2.7
—
—
—
0
0
568
5111
1.13
1.99
1.3
1.3
26.8
24.3
iu/ml
0.22
168
1541
515
4605
1.14
1.98
1.7
1.7
—
—
—
0
0
78
572
1.37
1.95
1.7
1.5
—
—
—
0
0
5
11
4.55
1.94
1.0
1.7
—
—
—
0
0
6
16
3.75
1.93
2.8
2.1
—
—
—
0
0
144
1153
1.26
1.92
1.2
1.3
0.2
1.1
u/ml
—
8
107
23
128
1.80
1.89
1.0
1.1
—
—
—
0
0
237
2005
1.20
1.88
2.8
2.8
1.6
1.7
%
0.71
208
1809
46
308
1.50
1.87
2.9
3.3
0.8
1.5
%
2.17
38
251
6
17
3.53
1.83
2.7
2.1
—
—
—
0
0
23
130
1.77
1.81
1.1
1.1
—
—
—
0
0
74
546
1.36
1.80
3.5
3.2
0.8
0.8
nmol/l
0.04
64
475
216
1820
1.20
1.80
1.2
1.2
—
—
—
0
0
87
659
1.33
1.79
2.1
2.1
1.4
1.8
ug/l
0.26
75
598
62
851
0.72
1.77
9.6
8.1
—
—
—
0
0
23
131
1.76
1.77
2.2
1.7
1.7
1.2
nmol/l
0.79
17
106
20
109
1.84
1.77
1.0
1.0
—
—
—
0
0
333
2915
1.16
1.76
2.9
2.6
7.1
7.2
umol/l
0.01
278
2493
49
338
1.46
1.75
2.2
2.6
7.1
7.2
mmol/l
0.12
49
331
19
104
1.83
1.67
2.5
2.2
—
—
—
0
0
23
134
1.72
1.66
2.0
1.6
—
—
—
0
0
221
1883
1.19
1.65
4.5
4.2
—
7.4
—
0
10
165
1368
1.22
1.65
2.4
2.3
66.7
67.6
g/l
0.84
157
1282
80
608
1.32
1.63
1.1
1.1
9.0
12.8
au/ml
—
6
48
194
1636
1.20
1.63
1.5
1.4
—
—
—
0
0
168
1398
1.21
1.62
1.4
1.4
8.2
8.4
u/l
0.07
133
1146
10
43
2.33
1.60
1.2
1.0
—
—
—
0
0
22
128
1.72
1.60
1.6
1.4
1136.8
2600.6
e6/l
2.85
17
90
8
32
2.50
1.59
1.1
1.0
—
—
—
0
0
239
2057
1.17
1.59
7.3
8.3
5.2
5.1
kpa
0.57
228
1972
239
2057
1.17
1.59
7.3
8.3
12.9
13.1
kpa
0.31
230
1975
359
3185
1.14
1.59
2.1
2.2
29.8
29.6
s
0.20
351
3077
614
5627
1.11
1.58
3.4
3.1
2.0
1.6
ug/l
0.63
536
5167
70
525
1.34
1.57
2.5
2.3
5.3
6.8
umol/l
0.50
47
386
129
1049
1.24
1.56
2.1
2.2
20.4
20.9
s
0.94
109
879
8
33
2.43
1.53
1.0
1.1
—
—
—
0
0
72
545
1.33
1.53
1.1
1.1
—
—
—
0
0
20
334
0.60
1.52
1.2
1.4
—
—
—
0
0
5
15
3.34
1.52
3.0
2.2
—
—
—
0
0
169
1418
1.20
1.51
5.0
4.2
106.2
83.8
ng/l
1.06
153
1294
51
366
1.40
1.51
2.2
2.5
1.3
1.5
mmol/l
1.00
51
356
26
162
1.61
1.49
3.2
3.1
1136.0
950.9
u/ml
0.17
26
162
150
1247
1.21
1.48
1.3
1.3
—
—
—
0
0
238
2061
1.17
1.48
7.4
8.3
0.9
1.0
mmol/l
0.12
201
1612
702
6503
1.10
1.47
1.7
1.7
—
—
—
0
0
37
252
1.47
1.45
1.1
1.1
279.7
277.5
mg/l
0.07
32
233
290
2555
1.15
1.44
1.2
1.2
—
—
—
0
0
276
2427
1.15
1.41
6.4
7.3
105.0
104.5
mmol/l
1.13
270
2373
210
1809
1.17
1.41
1.1
1.1
—
—
—
0
0
132
1091
1.22
1.40
2.0
2.0
—
—
—
0
0
33
223
1.48
1.36
4.7
6.1
12.0
7.1
mmol/l
0.59
27
191
164
1389
1.19
1.35
2.8
2.9
68.7
72.0
e9/l
0.57
122
1017
44
315
1.40
1.35
1.3
1.3
—
—
—
0
0
206
1784
1.16
1.31
1.4
1.4
—
—
—
0
0
126
1045
1.21
1.31
5.4
4.6
24.0
24.2
mmol/l
0.40
114
972
498
5422
0.90
1.29
3.4
3.3
1.0
1.0
kg/l
1.59
76
717
61
464
1.32
1.29
2.4
2.5
—
—
—
0
0
28
185
1.52
1.29
2.5
3.1
—
—
—
0
0
874
8227
1.08
1.27
2.0
1.9
—
—
—
0
0
51
379
1.35
1.27
1.7
1.4
—
—
—
0
0
33
227
1.46
1.26
2.6
2.9
0.3
0.2
e9/l
0.31
28
192
19
115
1.66
1.24
1.2
1.2
—
—
—
0
0
6
25
2.40
1.24
1.0
1.1
—
—
—
0
0
23
351
0.65
1.24
19.1
12.9
890.0
833.6
nmol/l
0.23
23
338
297
2653
1.13
1.23
2.5
2.3
13.4
13.5
nmol/l
0.03
269
2426
9
45
2.00
1.23
1.1
1.0
—
—
—
0
0
22
139
1.59
1.23
2.5
2.7
45.7
48.4
umol/l
0.22
14
123
12
63
1.91
1.22
1.2
1.2
—
—
—
0
0
24
360
0.66
1.20
28.0
18.5
1520.3
4061.2
nmol/l
0.47
24
348
98
803
1.23
1.17
1.0
1.1
—
—
—
0
0
164
1410
1.17
1.17
1.4
1.3
194.1
225.8
miu/ml
0.69
81
682
21
133
1.58
1.17
1.1
1.0
5.2
10.3
u/ml
—
5
17
56
429
1.31
1.16
1.2
1.2
—
—
—
0
0
114
951
1.21
1.15
1.1
1.1
5.8
1.7
u/ml
0.80
44
402
274
2451
1.13
1.13
1.2
1.2
162.3
146.1
iu/ml
0.31
105
968
69
546
1.27
1.13
1.2
1.2
—
—
—
0
0
17
103
1.65
1.12
2.8
2.5
137.0
205.6
e6/l
—
10
55
8
40
2.00
1.12
1.1
1.3
0.8
1.7
%
—
8
32
7
31
2.26
1.10
1.1
1.2
—
57.9
—
0
5
33
236
1.40
1.06
2.6
2.9
616.5
551.8
e6/l
0.28
28
196
97
804
1.21
1.06
1.0
1.1
—
—
—
0
0
65
516
1.26
1.05
1.2
1.1
16274.9
1511.1
iu/ml
0.42
16
142
77
624
1.24
1.04
1.4
1.5
—
—
—
0
0
94
779
1.21
1.04
2.1
2.0
4.8
4.4
iu/l
0.12
40
288
138
1185
1.17
1.03
1.5
1.7
—
—
—
0
0
31
221
1.41
1.02
1.0
1.0
—
—
—
0
0
91
753
1.21
1.02
1.2
1.4
511.5
467.1
mg/l
0.39
85
722
68
545
1.25
1.02
1.1
1.2
—
—
—
0
0
28
196
1.43
1.02
3.3
3.0
54.5
55.1
%
0.04
19
134
84
690
1.22
1.01
1.8
2.4
512.2
348.9
ug/l
0.27
77
642
56
440
1.28
0.99
4.0
3.1
—
—
—
0
0
11
188
0.58
0.99
1.3
1.3
1487.4
97010.2
e6/l
—
5
138
65
521
1.25
0.98
1.3
1.2
4.4
4.1
u/ml
0.07
26
237
84
693
1.22
0.98
1.6
1.5
—
—
—
0
0
13
212
0.61
0.98
1.9
3.0
35.6
44.7
%
—
6
65
36
481
0.75
0.98
1.4
1.7
4168.9
12827.5
e6/l
3.37
26
356
71
576
1.24
0.97
1.1
1.1
—
—
—
0
0
18
116
1.55
0.96
1.7
1.4
38725.6
34885.0
e6/l
0.07
11
69
698
6590
1.07
0.95
6.3
7.0
—
—
—
0
0
19
125
1.52
0.93
1.4
1.5
1.0
5.3
u/field
1.68
19
92
57
711
0.80
0.93
4.2
4.8
—
—
—
0
0
86
1027
0.83
0.92
1.3
1.3
—
—
—
0
0
9
52
1.73
0.92
1.0
1.2
—
—
—
0
0
21
142
1.48
0.92
1.5
2.1
—
—
—
0
0
38
287
1.33
0.91
1.2
1.5
283.8
327.8
pmol/l
0.42
29
224
78
645
1.21
0.91
1.6
1.5
107.0
105.1
u/ml
0.10
18
131
43
331
1.30
0.91
1.6
1.5
—
—
—
0
0
33
244
1.36
0.90
1.0
1.1
—
—
—
0
0
40
305
1.32
0.90
1.2
1.7
49.0
62.2
mu/l
0.48
34
274
42
323
1.30
0.89
2.6
3.3
—
—
—
0
0
70
575
1.22
0.87
1.3
1.2
—
—
—
0
0
110
943
1.17
0.87
1.1
1.1
—
—
—
0
0
357
3293
1.09
0.87
2.3
2.2
0.6
0.6
ug/l
0.11
167
1553
8
43
1.86
0.87
1.1
11.0
—
—
—
0
0
8
44
1.82
0.85
1.0
1.1
—
—
—
0
0
26
187
1.39
0.85
1.0
1.1
1485.3
1532.1
miu/ml
0.07
26
187
53
424
1.25
0.84
2.7
2.1
136.8
133.7
g/l
0.40
42
313
33
248
1.33
0.83
1.1
1.1
—
—
—
0
0
8
46
1.74
0.82
2.0
1.7
—
—
—
0
0
862
8238
1.06
0.82
1.6
1.5
—
—
—
0
0
209
2312
0.90
0.80
2.5
2.2
—
—
—
0
0
28
207
1.36
0.79
1.2
1.2
—
—
—
0
0
6
33
1.82
0.79
1.3
2.2
—
—
—
0
0
100
861
1.17
0.78
1.4
1.3
171.8
82.0
titre
0.83
11
92
21
148
1.42
0.77
1.7
1.8
6.7
3.0
mg/l
1.01
21
139
20
140
1.43
0.76
3.0
2.4
10.1
8.8
%
0.27
20
134
374
3484
1.08
0.75
3.1
2.6
3.1
3.1
e6/l
0.02
205
1763
5
24
2.08
0.74
1.4
1.0
—
—
—
0
0
30
227
1.32
0.74
1.7
2.1
32.6
32.5
pg
0.05
30
227
44
351
1.26
0.74
3.2
2.1
—
—
—
0
0
27
201
1.35
0.74
1.1
1.2
—
—
—
0
0
16
108
1.48
0.73
1.8
1.5
—
—
—
0
0
23
167
1.38
0.73
2.6
2.7
—
—
—
0
0
5
25
2.00
0.72
1.0
1.0
0.1
1.4
u/ml
—
5
11
6
108
0.55
0.72
1.2
2.1
—
—
—
0
0
114
999
1.15
0.72
1.0
1.1
1.5
3.2
u/ml
1.50
18
154
63
526
1.20
0.71
1.8
2.2
—
—
—
0
0
30
229
1.31
0.71
1.9
1.6
52.6
54.0
%
0.07
23
149
9
58
1.55
0.69
1.1
1.2
—
—
—
0
0
9
58
1.55
0.69
2.7
2.5
—
—
—
0
0
217
1982
1.10
0.69
1.4
1.3
65.3
36.3
au/ml
—
7
96
13
85
1.53
0.69
1.2
1.1
—
—
—
0
0
18
127
1.42
0.67
1.2
1.1
—
—
—
0
0
26
196
1.33
0.67
1.8
1.6
5.9
6.5
mmol/l
0.76
19
141
53
438
1.21
0.67
1.9
1.9
—
—
—
0
0
60
503
1.20
0.66
3.9
2.4
8.9
8.8
kpa
0.07
55
474
17
120
1.42
0.64
3.8
5.1
—
—
—
0
0
35
279
1.26
0.62
1.1
1.1
—
—
—
0
0
26
199
1.31
0.62
1.1
1.2
—
—
—
0
0
185
1688
1.10
0.62
1.1
1.1
274.0
218.0
titre
—
5
44
0
20
0.00
0.60
0.0
1.0
—
0.0
—
0
10
422
3988
1.07
0.60
3.6
3.2
468.8
452.6
ng/l
0.02
257
2440
200
2176
0.91
0.60
3.4
2.4
—
—
—
0
0
15
105
1.43
0.60
1.0
1.1
—
—
—
0
0
23
174
1.32
0.60
1.7
1.6
29.8
24.3
umol/l
0.32
23
166
231
2137
1.09
0.58
2.5
2.3
16.2
21.9
au/ml
0.90
17
202
83
726
1.15
0.57
1.6
1.4
0.6
0.5
nmol/l
0.19
65
613
12
81
1.48
0.57
1.0
1.1
—
—
—
0
0
12
81
1.48
0.57
1.0
1.1
—
—
—
0
0
12
81
1.48
0.57
1.0
1.1
—
—
—
0
0
42
347
1.21
0.56
1.3
1.3
—
47.1
—
0
21
6
37
1.62
0.55
1.8
3.6
—
—
—
0
0
10
65
1.54
0.55
1.3
1.6
—
—
—
0
0
10
65
1.54
0.55
1.0
1.1
—
—
—
0
0
57
486
1.18
0.55
3.1
2.6
87.3
156.0
ug/min
0.84
32
317
25
195
1.28
0.54
3.2
4.1
12.9
11.3
%
1.02
25
195
16
216
0.74
0.53
4.4
3.3
—
—
—
0
0
16
216
0.74
0.53
8.8
6.7
—
—
—
0
0
40
331
1.21
0.53
1.1
1.7
—
36.5
—
0
18
82
722
1.14
0.53
1.1
1.1
4.1
4.4
u/ml
0.07
32
293
34
277
1.23
0.52
1.1
1.5
66.1
68.7
mmol/l
0.08
22
232
96
855
1.13
0.52
1.1
1.1
1.3
2.6
u/ml
0.75
18
216
50
424
1.18
0.52
2.9
3.1
40.4
57.7
mg/l
0.51
33
334
330
3113
1.07
0.52
1.4
1.5
—
—
—
0
0
50
425
1.18
0.51
2.8
3.1
27.2
38.4
mg/l
0.81
33
335
19
144
1.32
0.50
1.1
1.1
—
—
—
0
0
17
127
1.34
0.49
1.0
1.1
—
—
—
0
0
25
198
1.26
0.49
2.1
2.3
—
—
—
0
0
27
216
1.25
0.49
1.1
1.2
—
—
—
0
0
175
1616
1.09
0.49
3.9
4.2
8.2
43.0
ug/l
0.91
118
1228
374
3550
1.06
0.49
2.8
2.6
2.4
2.4
mmol/l
0.09
323
3093
219
2347
0.93
0.48
3.5
2.3
—
—
—
0
0
13
93
1.40
0.48
3.1
2.9
—
—
—
0
0
29
236
1.23
0.46
1.1
1.1
—
—
—
0
0
16
120
1.33
0.46
1.1
1.1
—
—
—
0
0
5
83
0.60
0.45
1.6
1.2
—
—
—
0
0
23
183
1.26
0.44
1.2
1.2
—
—
—
0
0
7
51
1.37
0.44
1.3
1.5
—
—
—
0
0
167
1799
0.92
0.44
3.5
2.4
—
—
—
0
0
19
148
1.29
0.43
1.2
1.3
—
—
—
0
0
9
128
0.70
0.43
2.0
3.1
—
—
—
0
0
220
2343
0.93
0.43
3.2
2.2
—
—
—
0
0
5
31
1.61
0.43
2.6
3.5
—
—
—
0
0
5
31
1.61
0.43
1.0
1.0
—
—
—
0
0
524
5043
1.05
0.42
1.4
1.4
—
—
—
0
0
6
91
0.66
0.42
1.8
1.8
—
—
—
0
0
8
57
1.40
0.42
2.1
1.3
—
—
—
0
0
18
140
1.29
0.42
2.8
3.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
0.1
—
0
8
0
16
0.00
0.41
0.0
1.9
—
—
—
0
0
28
231
1.21
0.41
1.6
1.2
140.0
225.1
titre
—
5
49
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
42
361
1.17
0.40
2.6
2.3
—
—
—
0
0
146
1574
0.92
0.40
1.4
1.4
—
—
—
0
0
5
34
1.47
0.40
1.6
1.4
—
—
—
0
0
99
1086
0.91
0.40
1.3
1.4
—
—
—
0
0
33
390
0.84
0.40
1.5
1.3
83.8
149.2
pmol/l
—
7
121
18
141
1.28
0.40
1.4
1.5
136.5
136.8
nmol/l
0.01
18
141
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
7
102
0.69
0.39
1.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.6
3.6
31.6
48.6
umol/l
—
5
27
99
1084
0.91
0.39
1.3
1.4
—
—
—
0
0
54
475
1.14
0.39
3.8
3.2
40.7
35.0
umol/l
0.73
41
414
23
187
1.23
0.39
1.2
1.1
—
—
—
0
0
82
741
1.11
0.38
1.4
1.2
271.2
259.2
u/ml
0.12
57
482
219
2320
0.94
0.38
3.2
2.3
—
—
—
0
0
74
666
1.11
0.38
1.1
1.1
3.5
6.0
u/ml
0.64
30
273
30
252
1.19
0.37
2.1
3.1
889.3
768.6
e6/l
0.32
14
97
215
2029
1.06
0.37
2.3
2.4
3430.4
4742.7
u/l
0.37
77
756
20
161
1.24
0.37
3.3
2.9
0.8
0.9
nmol/l
0.49
14
123
21
171
1.23
0.35
1.2
1.2
—
—
—
0
0
92
842
1.10
0.35
1.0
1.1
0.6
1.2
u/ml
1.40
41
387
68
613
1.11
0.34
1.1
1.1
—
—
—
0
0
101
1096
0.92
0.34
6.7
8.1
25.4
24.4
mmol/l
1.45
94
1023
6
44
1.36
0.34
1.2
1.1
—
—
—
0
0
23
276
0.83
0.34
1.4
3.0
—
—
—
0
0
97
892
1.09
0.34
1.1
1.1
8.1
6.7
u/ml
0.25
55
513
104
1125
0.92
0.33
1.3
1.5
—
—
—
0
0
38
332
1.15
0.32
1.1
1.2
37.4
37.8
mg/l
0.03
32
271
15
119
1.26
0.31
1.3
1.5
—
—
—
0
0
132
1410
0.93
0.31
1.8
2.1
6.7
6.4
ug/l
0.08
115
1264
386
3723
1.04
0.31
3.1
2.4
0.8
1.1
e6/l
0.61
217
1993
28
324
0.86
0.29
4.5
4.6
35.0
88.1
u/ml
—
9
98
77
709
1.09
0.28
1.3
1.4
16.7
21.1
u/l
1.04
62
599
72
661
1.09
0.28
1.5
1.5
298.0
2320.4
e6/l
1.19
57
538
93
864
1.08
0.27
1.1
1.1
—
—
—
0
0
25
214
1.17
0.27
1.0
1.1
—
—
—
0
0
72
662
1.09
0.27
1.5
1.5
13.6
25.2
e6/l
0.67
56
512
8
65
1.23
0.27
1.4
1.4
—
—
—
0
0
5
74
0.68
0.26
2.6
1.9
—
—
—
0
0
36
321
1.12
0.24
1.1
1.1
277.8
231.4
mg/l
0.82
30
281
29
329
0.88
0.24
1.2
1.2
23.0
35.9
u/l
0.44
24
281
25
217
1.15
0.24
1.0
1.1
17.5
7.9
iu/ml
—
6
55
52
569
0.91
0.24
1.4
1.3
—
—
—
0
0
6
81
0.74
0.24
1.0
1.3
—
—
—
0
0
5
38
1.32
0.23
1.0
1.2
39.2
34.2
%
—
5
33
154
1468
1.05
0.23
1.1
1.1
—
—
—
0
0
7
92
0.76
0.22
2.4
2.3
—
—
—
0
0
148
1412
1.05
0.22
2.4
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
2110.2
—
0
11
0
11
0.00
0.21
0.0
1.3
—
0.2
—
0
5
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
131.7
—
0
10
65
604
1.08
0.21
1.0
1.1
0.3
0.7
u/ml
0.33
11
140
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
8
103
0.78
0.21
2.3
2.3
—
—
—
0
0
5
43
1.16
0.21
2.8
2.0
—
—
—
0
0
53
489
1.09
0.20
5.7
6.5
384.5
381.6
umol/l
0.04
41
436
6
48
1.25
0.20
1.2
1.1
—
—
—
0
0
117
1113
1.05
0.20
4.9
5.9
—
—
—
0
0
51
471
1.08
0.19
3.4
3.9
—
—
—
0
0
6
51
1.18
0.19
1.0
1.1
3.6
6.0
nmol/l
—
6
46
18
207
0.87
0.19
1.0
1.0
—
—
—
0
0
204
2110
0.96
0.18
15.6
14.6
1.2
1.1
inr
0.17
32
346
60
562
1.07
0.17
1.4
1.5
—
—
—
0
0
96
1006
0.95
0.16
4.9
3.3
—
—
—
0
0
17
192
0.88
0.14
2.1
1.5
—
—
—
0
0
9
83
1.08
0.14
1.3
1.6
—
—
—
0
0
40
372
1.08
0.14
1.6
1.5
—
—
—
0
0
23
208
1.11
0.14
1.3
1.5
—
—
—
0
0
8
97
0.82
0.13
1.8
2.6
22.2
16.8
umol/l
—
8
97
64
608
1.05
0.13
3.9
3.8
57.7
334.2
u/ml
1.27
55
521
16
142
1.13
0.12
1.9
1.7
—
—
—
0
0
63
662
0.95
0.12
1.3
1.3
2.8
2.9
ug/l
0.08
58
606
14
123
1.14
0.12
1.5
1.6
—
—
—
0
0
52
493
1.06
0.11
3.3
3.0
25.8
24.0
mg/l
0.14
34
308
16
143
1.12
0.11
1.3
1.2
—
—
—
0
0
473
4669
1.02
0.10
1.7
1.7
—
—
—
0
0
248
2433
1.02
0.10
2.8
2.7
38.0
40.0
u/l
0.15
217
2128
12
107
1.12
0.08
1.2
1.1
—
—
—
0
0
541
5464
0.99
0.08
3.1
3.1
—
—
—
0
0
5
60
0.83
0.08
1.4
1.5
—
—
—
0
0
5
62
0.81
0.08
1.2
1.2
—
—
—
0
0
11
123
0.89
0.08
1.0
1.4
—
—
—
0
0
6
71
0.84
0.07
1.0
1.9
—
—
—
0
0
17
184
0.92
0.07
2.3
1.5
24.2
34.2
%
0.58
12
116
65
629
1.03
0.07
1.1
1.1
—
—
—
0
0
162
1650
0.98
0.07
3.4
3.4
—
—
—
0
0
7
84
0.83
0.07
2.6
2.3
—
—
—
0
0
31
325
0.95
0.06
1.7
1.6
—
—
—
0
0
12
109
1.10
0.06
1.4
1.6
12.5
14.8
pmol/l
1.02
12
93
280
2829
0.99
0.05
1.4
1.3
—
—
—
0
0
155
1529
1.01
0.04
5.4
3.6
—
—
—
0
0
18
191
0.94
0.04
1.2
1.2
—
—
—
0
0
30
288
1.04
0.04
1.3
1.8
—
—
—
0
0
31
298
1.04
0.04
1.0
1.1
0.2
1.0
u/ml
—
10
87
10
91
1.10
0.04
1.8
1.5
2.4
4.1
%
—
5
25
127
1286
0.99
0.03
1.3
1.4
—
—
—
0
0
52
531
0.98
0.03
1.7
1.7
—
—
—
0
0
23
221
1.04
0.03
1.1
1.1
—
—
—
0
0
14
132
1.06
0.02
2.3
2.7
304.5
162.9
umol/l
—
8
62
62
610
1.02
0.02
1.0
1.1
3.2
2.9
u/ml
0.08
31
341
22
227
0.97
0.01
1.1
1.1
—
—
—
0
0
128
1289
0.99
0.01
2.4
2.7
152.6
130.3
ng/l
0.25
113
1119
141
1418
0.99
0.01
1.8
2.5
63.1
36.1
u/ml
0.59
136
1373
24
246
0.98
0.00
1.6
1.6
286.8
284.5
mosm/kgh2o
0.35
19
188
29
284
1.02
0.00
2.2
1.7
—
—
—
0
0
26
262
0.99
0.00
1.5
1.6
—
—
—
0
0
26
262
0.99
0.00
1.5
1.6
—
—
—
0
0
26
262
0.99
0.00
1.5
1.6
—
—
—
0
0
26
262
0.99
0.00
1.5
1.6
—
—
—
0
0
13
125
1.04
0.00
1.5
1.2
—
—
—
0
0
31
308
1.01
0.00
1.0
1.1
0.4
0.9
u/ml
—
10
69
21
205
1.02
0.00
3.2
2.2
—
—
—
0
0
26
265
0.98
0.00
1.2
1.2
—
—
—
0
0
84
844
1.00
0.00
1.3
1.3
—
—
—
0
0
75
754
0.99
0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
7
78
0.90
0.00
3.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
36.2
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.90
0.00
5.0
3.0
—
—
—
0
0
18
180
1.00
0.00
7.0
7.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
155.3
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
37.8
—
0
6

Mortality – FinRegistry

Association

Association between endpoint H8_EUSTSALP and mortality.

Females

Parameter HR [95% CI] p-value
H8_EUSTSALP 0.882 [0.71, 1.09] 0.255
Birth year 0.993 [0.98, 1.0] 0.125

During the follow-up period (1.1.1998 — 31.12.2019), 109 out of 3289 females with H8_EUSTSALP died.

Males

Parameter HR [95% CI] p-value
H8_EUSTSALP 0.873 [0.69, 1.1] 0.243
Birth year 0.99 [0.98, 1.0] 0.032

During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 2993 males with H8_EUSTSALP died.

Mortality risk

Mortality risk for people of age

years, who have H8_EUSTSALP.

N-year risk Females Males
1 0.092% 0.177%
5 0.469% 1.006%
10 1.221% 2.684%
15 2.401% 5.315%
20 4.328% 9.138%

Relationships between endpoints

Index endpoint: H8_EUSTSALP – Eustachian salpingitis and obstruction

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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