Fibrosarcoma, including Hilmo

C3_FIBROSARCOMA_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C47.5|C48.5|C49.5
  • Cause of death: ICD-10 C47.5|C48.5|C49.5
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 8810|8811|8814|8815|8821|8830|8832|8840
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

311

4. Check minimum number of events

None

311

5. Include endpoints

None

311

6. Filter based on genotype QC (FinnGen only)

291

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 291 140 151
Unadjusted period prevalence (%) 0.06 0.05 0.07
Median age at first event (years) 54.33 53.73 54.90

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
311
Matched controls
3110
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
83.1
76
*
H02AB02
ATC
dexamethasone; systemic
46.0
78.1
47
12
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
12.6
52.1
55
52
8832/3-C44.5
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin of trunk
+∞
47.1
44
*
C49.29
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip other or unspecified tumor
+∞
43.8
41
*
C49.25
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip fibrosarcoma
+∞
43.8
41
*
A03FA01
ATC
metoclopramide; systemic, rectal
5.6
38.5
91
214
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
37.2
35
*
ZZA00
NOMESCO Finland
Split skin graft
14.5
37.2
35
27
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
376.2
34.6
34
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
14.1
34.6
33
26
C49.20
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the lower extremity including the hip without histology
+∞
32.9
31
*
JN4BD
NOMESCO Finland
Extensive body CT
8.1
32.3
47
67
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
31.8
30
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
10.4
28.5
33
35
A04AA02
ATC
granisetron; systemic, transdermal
307.7
28.2
28
*
XX3DW
NOMESCO Finland
Time consuming IT work
7.6
27.5
42
63
A04AA01
ATC
ondansetron; systemic, rectal
10.9
26.0
29
29
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
7.5
25.7
39
58
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
10.2
24.8
29
31
8811/3-C49.2
ICD-O-3
Myxofibrosarcoma of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
24.3
23
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
23.2
22
*
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
9.3
23.1
29
34
C49.15
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder fibrosarcoma
+∞
22.1
21
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
22.1
21
*
115
Kela drug reimbursment
Breast cancer
+∞
22.1
21
*
ZZR00
NOMESCO Finland
Flap of skin
123.8
21.9
23
*
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
+∞
21.1
20
*
C49.21
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip malignant fibrotic histiocytoma
+∞
21.1
20
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
21.1
20
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
9.4
21.0
26
30
L03AA13
ATC
pegfilgrastim; parenteral
224.4
20.8
21
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
19.0
20.5
31
18
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
20.0
19
*
C49.2
ICD-10 Finland
Malignant neoplasm: Connective and soft tissue of lower limb, including hip
+∞
20.0
19
*
JN4AD
NOMESCO Finland
Body CT examination
6.2
19.5
35
62
WZC00
NOMESCO Finland
Treatment plan or consultation
3.1
19.2
114
490
Z51.5
ICD-10 Finland
Palliative care
7.6
19.0
28
40
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
18.9
18
*
8832/3-C44.7
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin of lower limb and hip
+∞
18.9
18
*
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
+∞
18.9
18
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
106.6
18.8
20
*
PJA12
NOMESCO Finland
Sentinel node biopsy
201.7
18.7
19
*
ZZR10
NOMESCO Finland
Flap of skin and muscle
201.7
18.7
19
*
JN4CD
NOMESCO Finland
Very extensive body CT
21.0
18.5
27
14
WX408
NOMESCO Finland
General anesthesy, balanced
3.1
17.9
101
419
C49.10
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder without histology
+∞
17.9
17
*
C49.39
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax other or unspecified tumor
+∞
16.8
16
*
C49.19
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder other or unspecified tumor
+∞
16.8
16
*
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
179.2
16.7
17
*
WF002
NOMESCO Finland
Radical radiotherapy
63.4
15.9
18
*
8832/3-C44.6
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin of upper limb and shoulder
+∞
15.8
15
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
89.7
15.7
17
*
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
12.2
15.6
28
25
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
30.4
15.4
20
7
ZXE30
NOMESCO Finland
More than five and less than seven hours
6.5
15.4
26
43
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
+∞
14.7
14
*
C49.11
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder malignant fibrotic histiocytoma
+∞
14.7
14
*
8830/3-C49.2
ICD-O-3
Malignant fibrous histiocytoma of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
14.7
14
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
14.7
14
*
C49.99
ICD-10 Finland
Malignant tumor in unspecified localization in connective tissue and soft tissue other or unspecified tumor
+∞
14.7
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
14.3
171
1016
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
78.7
13.7
15
*
C49.35
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thoracic fibrosarcoma
+∞
13.6
13
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
146.1
13.6
14
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
146.1
13.6
14
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
12.3
13.5
24
21
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.5
13.1
34
83
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
6.1
12.9
23
40
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
18.3
12.7
19
11
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
12.6
12
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
12.6
12
*
8832/3-C44.9
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin, NOS
+∞
12.6
12
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
12.6
12
*
159
Kela drug reimbursment
Pazopanib
+∞
12.6
12
*
WF001
NOMESCO Finland
Preoperative radiotherapy
+∞
12.6
12
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
4.8
11.7
27
60
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
11.5
11
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
11.5
11
*
A04AD12
ATC
aprepitant; systemic
+∞
11.5
11
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
11.5
11
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
11.5
11
*
NER30
NOMESCO Finland
Extended excision of soft tissue tumour of pelvis
+∞
11.5
11
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
11.5
11
*
N02AA05
ATC
oxycodone; systemic
2.9
11.5
62
246
ZXE20
NOMESCO Finland
More than three and less than five hours
3.0
11.5
56
210
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
11.2
69
293
R4120
NOMESCO Finland
Occupational therapy
3.9
11.1
34
94
WX402
NOMESCO Finland
General anaesthesia
2.7
11.1
68
288
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
62.2
10.7
12
*
HA1AA
NOMESCO Finland
X-ray mammography
8.7
10.5
22
27
C49.30
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax without histology
+∞
10.5
10
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
10.5
10
*
YX9VG
NOMESCO Finland
Other MRI eamination with high intensity magnet for dose design of radiotherapy
+∞
10.5
10
*
116
Kela drug reimbursment
Prostate cancer
+∞
10.5
10
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
10.5
10
*
C49.59
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the pelvis other or unspecified tumor
+∞
10.5
10
*
8830/3-C49.6
ICD-O-3
Malignant fibrous histiocytoma of connective, Subcutaneous and other soft tissues of trunk, NOS
+∞
10.5
10
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
10.5
10
*
C49.00
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the head, face and neck without histology
+∞
10.5
10
*
8810/3-C49.1
ICD-O-3
Fibrosarcoma, NOS, of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
10.5
10
*
343
Kela drug reimbursment
Pazopanib
+∞
10.5
10
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
10.5
10
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
10.5
10
*
8830/3-C49.1
ICD-O-3
Malignant fibrous histiocytoma of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
10.5
10
*
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
+∞
10.5
10
*
L03AA02
ATC
filgrastim; parenteral
+∞
10.5
10
*
C49.49
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the abdomen other or unspecified tumor
+∞
10.5
10
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
10.1
10.4
20
21
S18
ICPC
Laceration/cut
2.2
10.2
154
966
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
11.9
10.2
18
16
GD1AD
NOMESCO Finland
Thorax CT examination
4.1
9.9
28
73
B01AB05
ATC
enoxaparin; parenteral
2.2
9.5
105
579
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
103.0
9.5
10
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
9.4
9
*
Z42.4
ICD-10 Finland
Follow-up care involving plastic surgery of lower extremity
+∞
9.4
9
*
YN1BD
NOMESCO Finland
Extensive CT examination of extremities for dose design of radiotherapy
+∞
9.4
9
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
9.4
9
*
C49.95
ICD-10 Finland
Malignant tumor in unspecified localization in connective tissue and soft tissue fibrosarcoma
+∞
9.4
9
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
37.9
9.1
11
*
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
19.3
9.0
13
7
L02BG04
ATC
letrozole; oral
24.9
9.0
12
5
HAB40
NOMESCO Finland
Wedge excision of mammary gland
51.5
8.7
10
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
8.2
8.5
18
23
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
92.5
8.5
9
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
3.2
8.4
36
124
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.0
8.4
24
63
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
7.4
8.4
19
27
C49.90
ICD-10 Finland
Malignant tumor in unspecified localization in connective tissue and soft tissue without histology
+∞
8.4
8
*
C49.65
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the torso, unspecified localization fibrosarcoma
+∞
8.4
8
*
8810/3-C49.2
ICD-O-3
Fibrosarcoma, NOS, of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
8.4
8
*
L01AX03
ATC
temozolomide; systemic
+∞
8.4
8
*
C49.28
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip Ewing's sarcoma
+∞
8.4
8
*
C49.3
ICD-10 Finland
Malignant neoplasm: Connective and soft tissue of thorax
+∞
8.4
8
*
C49.55
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of pelvic fibrosarcoma
+∞
8.4
8
*
8811/3-C49.1
ICD-O-3
Myxofibrosarcoma of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
8.4
8
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
8.4
8
*
C49.45
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of abdominal fibrosarcoma
+∞
8.4
8
*
L02BA01
ATC
tamoxifen; oral
+∞
8.4
8
*
L02AE02
ATC
leuprorelin; implant, parenteral
34.3
8.1
10
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
12.3
7.6
13
11
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.2
7.6
15
17
B01AB10
ATC
tinzaparin; parenteral
3.1
7.5
32
110
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.7
7.5
41
163
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
82.0
7.4
8
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
82.0
7.4
8
*
R4110
NOMESCO Finland
Physiotherapy
2.1
7.4
91
517
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.3
7.3
28
90
17131
ICD-8 Finland
Malignant neoplasm of connective and other soft tissue, Lower limb (including hip)
+∞
7.3
7
*
L01BC06
ATC
capecitabine; oral
+∞
7.3
7
*
C49.1
ICD-10 Finland
Malignant neoplasm: Connective and soft tissue of upper limb, including shoulder
+∞
7.3
7
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
7.3
7
*
C49.05
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the head, face and neck fibrosarcoma
+∞
7.3
7
*
Z42.2
ICD-10 Finland
Follow-up care involving plastic surgery of other parts of trunk
+∞
7.3
7
*
YN1AD
NOMESCO Finland
CT examination of extremities for dose design of radiotherapy
+∞
7.3
7
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
+∞
7.3
7
*
8811/3-C49.5
ICD-O-3
Myxofibrosarcoma of connective, Subcutaneous and other soft tissues of pelvis
+∞
7.3
7
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
7.3
7
*
NAR40
NOMESCO Finland
Block excision of soft tissue tumour of spine, unspecified
+∞
7.3
7
*
NB1DG
NOMESCO Finland
Shoulder and humerus very extensive MRI examination with high intensity magnet
20.6
7.2
10
5
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.6
7.0
17
27
Z31.5
ICD-10 Finland
Genetic counselling
5.7
7.0
19
35
GA1CG
NOMESCO Finland
Extensive MRI of chest
41.0
6.8
8
*
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
41.0
6.8
8
*
GA1BG
NOMESCO Finland
MRI of chest
41.0
6.8
8
*
N03AX16
ATC
[U] pregabalin
2.1
6.7
79
440
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
12.6
6.6
11
9
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
7.1
6.6
15
22
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.2
6.5
26
86
NE1CM
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with 3 Tesla magnet
71.3
6.4
7
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
71.3
6.4
7
*
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
9.5
6.3
12
13
N02AA01
ATC
morphine; systemic, rectal
18.5
6.3
9
5
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
18.5
6.3
9
5
C49.31
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax malignant fibrotic histiocytoma
+∞
6.3
6
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
C49.09
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the head, face and neck other or unspecified tumor
+∞
6.3
6
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
6.3
6
*
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
+∞
6.3
6
*
NCR30
NOMESCO Finland
Extended excision of soft tissue tumour of elbow or forearm
+∞
6.3
6
*
C49.50
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the pelvis without histology
+∞
6.3
6
*
GDC00
NOMESCO Finland
Lobectomy of lung
+∞
6.3
6
*
NJ3DG
NOMESCO Finland
Very extensive MRI examination of extremities with high intensity magnet
+∞
6.3
6
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
6.3
6
*
WZC30
NOMESCO Finland
Teaching
2.4
6.0
43
194

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
72
55
16.73
78.61
1.4
1.3
—
—
—
0
0
154
676
3.53
26.60
2.6
1.6
—
—
—
0
0
59
150
4.62
21.99
1.5
1.1
—
—
—
0
0
161
1002
2.26
11.21
2.6
2.3
—
—
—
0
0
37
118
3.42
9.83
4.2
1.4
4.37
2.60
ug/l
0.43
28
88
114
672
2.10
8.56
2.4
2.0
—
—
—
0
0
13
12
11.24
7.36
1.4
1.0
—
—
—
0
0
11
8
14.19
6.94
2.0
1.5
18.69
12.76
ug/l
—
11
8
175
1269
1.87
6.71
11.9
6.3
3.87
4.33
e9/l
1.96
155
1098
25
84
3.15
6.11
1.2
1.2
—
—
—
0
0
224
1809
1.85
5.55
9.4
5.1
80.70
77.31
u/l
0.64
214
1648
160
1175
1.74
5.48
9.4
3.7
12.86
13.73
umol/l
0.18
154
1100
62
354
1.94
4.79
2.1
1.8
—
—
—
0
0
142
1036
1.68
4.78
6.5
5.7
1.21
1.21
mmol/l
0.25
136
934
94
623
1.73
4.46
4.4
3.9
—
—
—
0
0
142
1076
1.59
3.88
6.5
5.2
57.09
57.36
%
0.09
135
1005
48
273
1.90
3.73
5.4
6.9
0.80
1.64
mmol/l
0.78
38
221
9
16
5.76
3.68
1.7
4.9
—
—
—
0
0
142
1086
1.57
3.67
6.8
5.4
27.27
27.73
%
0.18
135
1014
139
1060
1.56
3.63
7.2
5.5
—
—
—
0
0
148
1145
1.56
3.62
10.1
16.1
1.01
1.32
inr
15.10
32
327
148
1147
1.55
3.58
7.1
6.3
1.20
1.21
mmol/l
1.03
131
1003
150
1168
1.55
3.54
6.7
5.3
1.67
1.89
e9/l
3.10
135
1023
147
1144
1.54
3.46
6.7
5.2
0.57
0.60
e9/l
0.80
131
982
138
1065
1.53
3.34
7.1
5.5
8.87
8.67
%
0.30
131
990
137
1060
1.52
3.25
6.8
5.3
3.02
2.88
%
0.27
130
984
10
24
4.27
3.22
1.4
1.4
23.97
159.12
u/ml
—
10
24
146
1148
1.51
3.20
6.8
5.2
0.04
0.04
e9/l
0.32
129
987
173
1424
1.48
2.95
4.5
4.4
6.48
6.76
mmol/l
1.39
167
1330
78
544
1.58
2.91
11.8
4.9
—
—
—
0
0
45
273
1.76
2.85
1.8
1.8
—
—
—
0
0
32
174
1.94
2.85
2.8
2.0
0.21
0.20
g/l
0.17
32
156
148
1187
1.47
2.84
7.0
5.4
0.19
0.20
e9/l
0.24
132
1038
26
132
2.06
2.80
7.5
10.6
25.02
25.10
mmol/l
0.05
26
132
131
1031
1.47
2.75
7.1
5.2
0.72
0.66
%
0.81
124
953
7
14
5.09
2.74
1.0
1.0
—
—
—
0
0
27
142
1.99
2.65
5.9
4.0
0.09
0.03
%
0.24
11
29
47
296
1.69
2.62
5.4
6.1
105.23
104.11
mmol/l
1.33
47
296
28
152
1.93
2.52
5.8
3.9
1.08
0.81
%
0.26
12
40
8
21
3.88
2.48
1.8
3.8
—
—
—
0
0
26
139
1.95
2.45
6.1
4.0
0.00
0.08
%
—
10
25
25
137
1.90
2.21
6.3
4.0
0.56
0.49
%
—
9
34
5
10
5.06
2.08
4.8
1.9
2.84
5.16
nmol/l
—
5
10
95
743
1.40
1.95
6.5
2.1
2.35
2.36
mmol/l
0.04
85
625
9
33
2.78
1.94
1.3
1.4
—
—
—
0
0
16
78
2.11
1.94
4.7
3.1
0.17
0.63
g/l
0.92
11
22
24
136
1.83
1.93
6.3
8.9
0.68
0.71
%
0.17
24
136
88
683
1.40
1.88
5.0
3.1
7.40
7.40
ph
0.25
23
108
32
200
1.67
1.86
6.9
7.0
1.23
1.45
mmol/l
0.78
32
194
227
2054
1.39
1.80
21.5
15.1
15.69
15.04
%
0.71
227
2017
90
707
1.38
1.78
3.8
4.0
—
—
—
0
0
201
1789
1.35
1.74
3.6
4.0
11.83
12.00
mm/h
0.06
179
1638
0
46
0.00
1.72
0.0
1.2
—
16.09
—
0
39
71
540
1.41
1.69
1.4
1.3
—
—
—
0
0
21
120
1.80
1.67
6.5
9.4
—
—
—
0
0
6
19
3.20
1.67
1.8
4.3
0.67
0.64
%
—
6
14
7
25
2.84
1.66
1.0
1.6
—
—
—
0
0
123
1027
1.33
1.62
11.9
7.9
0.00
0.01
e9/l
0.42
108
829
269
2526
1.48
1.57
14.9
12.2
—
—
—
0
0
23
138
1.72
1.57
6.7
8.8
1.39
1.50
%
0.29
23
138
89
713
1.35
1.54
2.7
3.0
70.10
131.73
e6/l
0.26
69
544
33
221
1.55
1.48
1.5
1.3
—
—
—
0
0
9
40
2.29
1.41
1.3
1.4
—
—
—
0
0
29
192
1.56
1.38
6.4
7.1
—
—
—
0
0
37
259
1.49
1.37
3.1
2.1
13.71
9.00
umol/l
0.40
31
224
80
649
1.31
1.26
2.8
2.8
0.61
0.49
e6/l
0.18
63
483
9
45
2.03
1.24
2.6
4.0
—
—
—
0
0
257
2420
1.36
1.23
17.3
12.8
25.01
23.96
mg/l
0.18
210
1873
30
208
1.49
1.18
1.6
2.2
67.76
66.40
e9/l
0.06
25
160
10
182
0.53
1.14
2.2
2.5
—
23.03
—
0
7
179
1620
1.25
1.13
3.4
4.2
—
—
—
0
0
23
154
1.53
1.07
2.7
2.8
3.73
5.03
e9/l
0.89
18
122
189
1730
1.24
1.03
3.4
3.9
—
—
—
0
0
5
106
0.46
1.03
1.2
1.8
—
—
—
0
0
97
827
1.25
1.03
3.0
3.6
479.64
75.82
e6/l
0.54
71
581
49
382
1.34
1.02
2.9
2.9
1.16
2.74
e6/l
0.93
25
201
30
408
0.71
1.01
1.3
1.3
21.30
36.32
iu/ml
—
5
137
75
622
1.27
1.00
2.9
2.8
—
—
—
0
0
218
2311
0.81
0.91
5.9
6.0
39.54
40.32
mmol/mol
0.88
202
2141
45
563
0.77
0.89
1.4
1.7
467.33
438.93
pmol/l
0.18
36
455
8
42
1.93
0.89
1.8
4.1
—
—
—
0
0
14
87
1.64
0.89
2.0
2.0
—
—
—
0
0
24
170
1.45
0.88
3.7
4.7
—
—
—
0
0
25
335
0.72
0.79
1.4
1.3
905.00
492.84
titre
—
8
81
5
24
2.10
0.75
1.4
1.5
—
—
—
0
0
7
40
1.77
0.71
2.7
3.6
56.57
59.93
%
—
7
40
7
40
1.77
0.71
2.6
3.2
3.32
4.75
e9/l
—
7
40
24
179
1.37
0.69
4.6
3.4
—
—
—
0
0
110
985
1.18
0.69
2.3
2.6
235.14
119.64
ug/l
1.06
100
895
14
202
0.68
0.68
1.3
1.4
—
—
—
0
0
20
145
1.41
0.67
1.7
1.5
—
—
—
0
0
41
498
0.80
0.66
1.8
1.7
1162.87
1228.32
nmol/l
0.17
31
385
19
256
0.73
0.64
1.7
1.6
—
—
—
0
0
10
63
1.61
0.62
2.9
4.9
—
—
—
0
0
10
63
1.61
0.62
1.2
1.1
—
—
—
0
0
55
468
1.21
0.60
2.1
2.7
566.50
530.20
mosm/kgh2o
0.62
50
389
12
81
1.50
0.58
1.1
1.2
—
—
—
0
0
9
62
1.46
0.53
8.6
5.3
1.19
1.61
mg/l
—
9
56
6
99
0.60
0.52
4.2
7.4
—
—
—
0
0
27
216
1.27
0.51
4.1
3.6
—
—
—
0
0
83
744
1.16
0.51
2.4
2.2
60.18
62.42
u/l
0.10
76
686
165
1551
1.14
0.51
3.3
3.0
43.62
46.46
u/l
0.29
157
1433
267
2597
1.20
0.49
12.8
8.7
27.42
25.54
u/l
0.91
256
2490
17
128
1.35
0.49
1.1
1.3
75.04
112.81
iu/ml
—
5
52
7
46
1.53
0.48
2.1
3.1
5.27
5.08
kpa
—
7
46
7
46
1.53
0.48
2.1
3.1
8.27
8.19
kpa
—
7
46
241
2487
0.86
0.47
4.5
5.1
2.73
2.70
mmol/l
0.23
218
2285
16
120
1.35
0.47
3.8
6.7
—
—
—
0
0
16
121
1.34
0.45
1.2
1.2
—
—
—
0
0
12
162
0.73
0.43
2.4
2.9
—
—
—
0
0
5
31
1.62
0.43
1.6
1.4
162.40
61.66
pmol/l
—
5
31
66
734
0.87
0.42
2.8
3.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
65.00
—
0
9
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
34
288
1.20
0.41
2.0
2.1
1.87
1.63
%
0.45
27
258
0
16
0.00
0.41
0.0
1.8
—
82.94
—
0
16
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
93
1008
0.89
0.40
2.9
3.7
21.39
43.18
ng/l
3.69
68
723
26
215
1.23
0.39
1.2
1.4
—
—
—
0
0
29
244
1.21
0.38
1.1
1.4
—
—
—
0
0
85
780
1.12
0.37
2.8
3.1
30.24
137.74
mg/l
0.71
54
501
5
37
1.36
0.37
1.0
1.1
—
—
—
0
0
46
517
0.87
0.34
3.5
4.1
28.51
385.05
ng/l
2.22
36
419
6
45
1.34
0.34
8.3
2.7
54.83
65.51
%
—
6
45
44
495
0.87
0.33
1.3
1.3
0.56
1.60
u/ml
—
8
141
38
432
0.86
0.33
1.5
1.3
2.44
2.61
g/l
0.20
23
265
17
208
0.81
0.32
4.4
3.0
—
—
—
0
0
20
165
1.23
0.32
1.3
1.6
—
—
—
0
0
12
153
0.78
0.31
4.3
1.4
—
—
—
0
0
11
142
0.77
0.31
3.2
1.6
—
—
—
0
0
7
52
1.35
0.31
1.0
1.8
0.70
0.88
nmol/l
—
7
42
17
207
0.81
0.31
2.5
1.8
356.88
381.20
nmol/l
0.17
17
188
16
129
1.25
0.31
3.1
3.7
—
—
—
0
0
16
129
1.25
0.31
1.0
1.3
—
—
—
0
0
16
196
0.81
0.31
3.9
3.9
89.42
79.15
ng/l
0.24
16
176
58
635
0.89
0.30
2.6
2.4
345.92
9298.06
umol/l
3.56
51
552
34
299
1.15
0.29
1.8
1.7
—
—
—
0
0
88
824
1.09
0.27
3.3
3.7
4.80
29.63
mg/mmol
0.60
58
514
5
71
0.70
0.26
1.0
1.8
7.10
11.90
mg/l
—
5
66
238
2431
0.91
0.26
4.2
4.6
4.62
4.59
mmol/l
0.15
218
2243
275
2708
1.13
0.26
25.5
18.7
40.32
40.23
%
0.10
256
2517
275
2710
1.13
0.24
25.8
18.6
4.49
4.50
e12/l
0.14
269
2613
65
604
1.10
0.24
4.5
3.9
0.00
0.00
estimate
-0.00
25
177
87
820
1.08
0.23
2.8
3.1
7.68
7.70
mmol/l
0.01
76
692
275
2711
1.12
0.23
25.8
18.6
7.13
6.74
e9/l
0.41
269
2617
236
2407
0.92
0.23
4.1
4.5
1.41
1.47
mmol/l
1.49
215
2204
7
91
0.76
0.23
1.1
1.2
—
0.24
—
0
7
188
1827
1.07
0.22
3.6
3.7
15.06
14.94
pmol/l
0.32
171
1644
237
2415
0.92
0.22
4.4
4.6
5.94
6.02
mmol/l
0.47
216
2186
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
10.6
—
0.73
—
0
11
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
25.0
—
1675.92
—
0
12
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
15.6
—
909.75
—
0
12
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.7
—
24.75
—
0
12
17
145
1.18
0.21
1.1
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
3.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
52
1.16
0.19
1.2
1.4
—
—
—
0
0
10
81
1.24
0.19
1.7
1.8
—
—
—
0
0
93
888
1.07
0.18
4.8
3.8
2.50
2.00
ug/l
0.59
80
781
7
59
1.19
0.18
4.4
3.0
—
—
—
0
0
35
320
1.11
0.18
1.3
1.2
—
—
—
0
0
274
2708
1.10
0.17
25.9
18.6
245.00
246.97
e9/l
0.22
268
2623
33
301
1.11
0.17
2.0
2.3
19.18
23.64
%
1.29
28
263
24
215
1.13
0.17
1.7
1.4
—
—
—
0
0
12
101
1.20
0.17
2.8
4.4
—
—
—
0
0
120
1159
1.06
0.16
3.6
3.7
0.00
0.01
estimate
0.50
28
195
14
161
0.86
0.15
1.1
1.2
—
—
—
0
0
9
79
1.14
0.15
1.0
1.2
—
—
—
0
0
15
131
1.15
0.14
3.8
3.1
4.56
4.73
pmol/l
0.36
15
115
8
99
0.80
0.14
1.0
1.1
—
—
—
0
0
16
142
1.13
0.13
1.1
1.2
286.19
154.95
u/ml
0.47
16
126
81
841
0.95
0.12
2.7
3.0
—
—
—
0
0
54
514
1.06
0.12
1.8
1.6
1.14
1.12
mg/l
0.02
43
390
61
636
0.95
0.11
1.6
1.6
1.35
1.38
mmol/l
0.13
53
522
118
1152
1.04
0.10
4.6
5.2
0.00
0.00
estimate
-0.00
24
176
120
1172
1.04
0.10
3.6
3.7
0.00
0.02
estimate
0.50
24
174
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
36
379
0.94
0.08
1.3
1.3
1.15
8.13
u/ml
2.00
12
149
5
61
0.82
0.08
1.4
1.3
—
—
—
0
0
5
61
0.82
0.08
1.4
1.3
—
—
—
0
0
5
60
0.83
0.08
1.4
1.3
—
—
—
0
0
23
246
0.93
0.08
2.0
2.3
91.43
151.06
ug/g
0.88
23
194
7
64
1.10
0.08
2.9
2.5
—
—
—
0
0
231
2332
0.96
0.08
3.6
4.1
1.40
1.29
mmol/l
1.15
211
2116
6
73
0.82
0.07
1.0
1.2
—
2.45
—
0
11
8
77
1.04
0.07
2.6
4.6
3.81
3.98
mmol/l
—
8
77
55
569
0.96
0.07
3.8
3.6
—
—
—
0
0
63
611
1.04
0.07
1.4
1.5
23.77
21.44
nmol/l
0.41
56
521
29
275
1.06
0.07
1.3
1.4
—
—
—
0
0
106
1040
1.03
0.06
1.9
2.0
103.15
94.40
pmol/l
0.88
62
517
15
161
0.93
0.05
1.3
1.4
—
—
—
0
0
62
613
1.01
0.01
2.0
2.1
2.99
3.01
mg/l
0.03
54
515
13
128
1.02
0.00
1.2
2.9
0.25
0.23
e6/l
0.05
13
122
13
129
1.01
0.00
2.4
2.5
—
—
—
0
0
50
499
1.00
0.00
2.6
2.6
0.60
0.73
ug/l
1.04
34
320
222
2223
1.00
0.00
4.4
4.6
1.83
1.97
mu/l
1.06
204
2010
62
616
1.01
0.00
3.4
3.4
—
—
—
0
0
5
59
0.84
0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
2.67
—
0
9
0
9
0.00
-0.00
0.0
3.8
—
1.82
—
0
9
6
67
0.89
-0.00
6.8
1.3
39.52
43.58
mg/l
—
6
57
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
-0.00
6.8
1.2
26.83
30.59
mg/l
—
6
56
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
60
1.00
-0.00
8.3
4.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
15.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
17.05
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
-0.00
1.8
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
56.38
—
0
8
0
7
0.00
-0.00
0.0
15.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
22.97
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_FIBROSARCOMA_WIDE – Fibrosarcoma, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).