Acute nephritic syndrome

N14_ACUTENEPHRITIC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N00#
  • Hospital discharge: ICD-9 580
  • Hospital discharge: ICD-8 580
  • Hospital discharge: excluded ICD-9 5804
  • Cause of death: ICD-10 N00#
  • Cause of death: ICD-9 580
  • Cause of death: ICD-8 580
  • Cause of death: excluded ICD-9 5804

2 out of 7 registries used, show all original rules.

795

4. Check minimum number of events

None

795

5. Include endpoints

None

795

6. Filter based on genotype QC (FinnGen only)

795

Control definitions (FinnGen only)

Control exclude
N14_GLOMERULAR

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N00-N08
Name in latin
Syndroma nephriticum acutum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6888 2571 4253
Only index persons 5423 2070 3353
Unadjusted period prevalence (%)
Whole population 0.10 0.07 0.12
Only index persons 0.11 0.08 0.13
Median age at first event (years)
Whole population 33.02 34.02 32.14
Only index persons 28.39 28.38 28.39

-FinnGen-

Key figures

All Female Male
Number of individuals 795 330 465
Unadjusted period prevalence (%) 0.17 0.11 0.20
Median age at first event (years) 31.34 28.60 33.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
732
Matched controls
7321
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
58099
ICD-8 Finland
Acute nephritis
+∞
323.0
343
*
N00.9
ICD-10 Finland
Acute nephritic syndrome, Unspecified
+∞
161.6
149
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
45.8
92.2
113
29
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
54.9
87.8
104
22
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
58.4
86.2
101
20
A11CC03
ATC
alfacalcidol; systemic
27.5
69.3
96
40
Z94.0
ICD-10 Finland
Kidney transplant status
69.4
65.8
75
12
A12AA04
ATC
calcium carbonate; oral
49.0
62.1
75
17
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
+∞
61.3
58
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
60.2
57
*
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
49.8
59.8
72
16
L04AA06
ATC
mycophenolic acid; systemic
25.9
59.1
83
36
N00.0
ICD-10 Finland
Acute nephritic syndrome, Minor glomerular abnormality
+∞
57.0
54
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
9.6
55.1
118
143
L04AD01
ATC
ciclosporin; systemic
22.5
54.0
79
39
R80
ICD-10 Finland
Isolated proteinuria
151.3
53.6
56
*
127
Kela drug reimbursment
Transplant complication
27.8
53.2
73
29
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
52.9
53.0
63
13
N04.0
ICD-10 Finland
Nephrotic syndrome, minor glomerular abnormality
+∞
52.7
50
*
N18.8
ICD-10 Finland
Other chronic renal failure
17.2
51.6
83
54
TK800
NOMESCO Finland
Hemodialysis
19.4
50.1
77
44
N18.0
ICD-10 Finland
End-stage renal disease
41.4
49.0
61
16
B03XA02
ATC
darbepoetin alfa; parenteral
36.8
47.8
61
18
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
109.5
47.4
51
5
Z49.1
ICD-10 Finland
Extracorporeal dialysis
33.1
46.6
61
20
H02AB04
ATC
methylprednisolone; systemic
4.4
45.8
192
549
137
Kela drug reimbursment
Uraemia requiring dialysis
76.3
44.6
50
7
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
60.7
44.0
51
9
C03CA01
ATC
furosemide; systemic
3.3
43.1
291
1228
L04AA01
ATC
[U] ciclosporin; systemic
21.7
42.1
62
31
N00.2
ICD-10 Finland
Acute nephritic syndrome, Diffuse membranous glomerulonephritis
+∞
40.0
38
*
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
+∞
38.9
37
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
75.8
38.4
43
6
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
194.5
36.1
37
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
35.0
160
483
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
34.7
33
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
68.5
34.3
39
6
N03.0
ICD-10 Finland
Chronic nephritic syndrome, minor glomerular abnormality
+∞
33.6
32
*
V03AE01
ATC
polystyrene sulfonate; oral
24.4
32.6
46
20
B03XA01
ATC
erythropoietin; parenteral
31.7
32.0
42
14
N04.2
ICD-10 Finland
Nephrotic syndrome, diffuse membranous glomerulonephritis
+∞
31.5
30
*
N03.2
ICD-10 Finland
Chronic nephritic syndrome, diffuse membranous glomerulonephritis
+∞
30.4
29
*
5809A
ICD-9 Finland
Acute glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS ACUTA NUD,EI NEFR SDR]
+∞
30.4
29
*
B05DA
ATC
Isotonic solutions
111.4
29.9
32
*
N00.8
ICD-10 Finland
Acute nephritic syndrome, Other
+∞
28.3
27
*
Z49.2
ICD-10 Finland
Other dialysis
78.2
27.0
30
*
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
+∞
26.2
25
*
N00.3
ICD-10 Finland
Acute nephritic syndrome, Diffuse mesangial proliferative glomerulonephritis
+∞
26.2
25
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
9.0
26.0
56
67
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
28.2
26.0
35
13
L04AX01
ATC
azathioprine; systemic
5.7
26.0
78
151
B05DB
ATC
Hypertonic solutions
140.0
25.8
27
*
205
Kela drug reimbursment
Chronic hypertension
2.5
25.7
252
1254
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.7
24.9
90
214
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.0
24.9
71
129
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.6
24.4
64
104
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
69.9
24.0
27
*
58399
ICD-8 Finland
Nephritis, unqualified
+∞
23.0
22
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
23.0
22
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
53.8
22.2
26
5
58199
ICD-8 Finland
Nephrotic syndrome
+∞
22.0
21
*
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
22.0
21
*
N19
ICD-10 Finland
Unspecified kidney failure
7.3
20.6
50
73
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.4
20.5
77
190
196
Kela drug reimbursment
Paricalcitol and cinacalcet
49.5
20.3
24
5
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
19.9
19
*
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
+∞
19.9
19
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.4
19.3
73
181
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
19.2
241
1317
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
56.6
19.0
22
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
13.4
18.1
31
24
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
184.3
17.6
18
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
64.9
16.8
19
*
V03AE02
ATC
sevelamer; oral
64.9
16.8
19
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
64.9
16.8
19
*
7151
FHL
Kidney transplantation
+∞
16.7
16
*
58209
ICD-8 Finland
Chronic nephritis, Unspecified
+∞
16.7
16
*
N03.5
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
16.7
16
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.0
16.2
67
181
C09AA02
ATC
enalapril; systemic
2.3
16.1
167
824
L01AA01
ATC
cyclophosphamide; systemic
25.1
16.1
22
9
C08CA01
ATC
amlodipine; oral
2.0
15.8
267
1631
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
15.7
15
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
+∞
15.7
15
*
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
+∞
15.7
15
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.4
15.7
41
67
C02AC05
ATC
moxonidine; oral
4.7
15.6
54
123
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
15.5
97
359
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
7.4
15.2
36
51
78930
ICD-8 Finland
Abnormal urinary constituents of unspecified cause, Haematuria
32.4
14.9
19
6
N00.5
ICD-10 Finland
Acute nephritic syndrome, Diffuse mesangiocapillary glomerulonephritis
+∞
14.6
14
*
5809B
ICD-9 Finland
Acute glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS ACUTA NUD,NEFR SDR]
+∞
14.6
14
*
C08CA02
ATC
felodipine; oral
2.9
13.9
87
320
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
54.4
13.9
16
*
V03AE03
ATC
lanthanum carbonate; oral
76.6
13.6
15
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
+∞
13.6
13
*
N00.7
ICD-10 Finland
Acute nephritic syndrome, Diffuse crescentic glomerulonephritis
+∞
13.6
13
*
N00.1
ICD-10 Finland
Acute nephritic syndrome, Focal and segmental glomerular lesions
+∞
13.6
13
*
H02AB06
ATC
prednisolone; systemic
1.8
13.5
335
2313
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
142.5
13.5
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
13.4
317
2150
H05BX01
ATC
cinacalcet; oral
18.6
13.4
20
11
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
40.9
13.2
16
*
M04AA01
ATC
allopurinol; systemic
2.5
13.2
112
496
C08CA13
ATC
lercanidipine; oral
2.5
13.0
106
459
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
50.9
12.9
15
*
C10AA05
ATC
atorvastatin; oral
1.8
12.4
267
1745
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
38.2
12.2
15
*
TK810
NOMESCO Finland
Hemofiltration
16.7
11.7
18
11
321
Kela drug reimbursment
Paricalcitol and cinacalcet
16.7
11.7
18
11
L01BB01
ATC
NA
66.0
11.6
13
*
5828A
ICD-9 Finland
Chronic glomerulonephritis, With other specified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA ALIA DEF,EI NEFR SDR]
+∞
11.5
11
*
5808A
ICD-9 Finland
Acute glomerulonephritis, With other specified pathological lesion in kidney[GLOMERULONEPHRITIS ACUTA ALIA,EI NEFR SDR]
+∞
11.5
11
*
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
121.8
11.5
12
*
I15.0
ICD-10 Finland
Renovascular hypertension
20.4
11.2
16
8
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
11.0
126
642
N04.3
ICD-10 Finland
Nephrotic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
10.4
10
*
5813A
ICD-9 Finland
Nephrotic syndrome, With lesion of minimal change glomerulonephritis
+∞
10.4
10
*
5819X
ICD-9 Finland
Nephrotic syndrome with unspecified pathological lesion in kidney
+∞
10.4
10
*
R50.9
ICD-10 Finland
Fever, unspecified
2.2
10.4
111
546
R31
ICD-10 Finland
Unspecified haematuria
2.4
10.0
88
397
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.0
10.0
31
64
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
40.6
10.0
12
*
TK820
NOMESCO Finland
Peritoneal dialysis
40.6
10.0
12
*
ZX120
NOMESCO Finland
Intravenous
2.4
9.8
83
364
WW200
NOMESCO Finland
Immunization
4.3
9.7
35
85
3AC01
NOMESCO Finland
NA
8.0
9.7
21
27
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.3
9.6
88
405
C08CA05
ATC
nifedipine; systemic
2.8
9.5
60
225
Z99.2
ICD-10 Finland
Dependence on renal dialysis
101.3
9.4
10
*
M31.3
ICD-10 Finland
Wegener granulomatosis
30.4
9.4
12
*
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
+∞
9.4
9
*
D638, N188
ICD-10 Finland
NA
+∞
9.4
9
*
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
9.4
9
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
15.8
9.1
14
9
C07AB02
ATC
metoprolol; systemic
1.9
8.8
144
843
H02AB09
ATC
hydrocortisone; systemic
4.7
8.7
28
61
M05BA04
ATC
alendronic acid; oral
2.7
8.6
58
225
C09CA07
ATC
telmisartan; oral
2.6
8.6
61
243
C09CA01
ATC
losartan; oral
1.8
8.6
168
1042
XPX08
NOMESCO Finland
Intraoperative flow measurement
9.1
8.6
17
19
A46
ICD-10 Finland
Erysipelas
2.1
8.6
105
551
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
91.1
8.4
9
*
L04AA05
ATC
[U] tacrolimus; systemic
+∞
8.3
8
*
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
8.3
74
337
A02BC01
ATC
omeprazole; systemic
1.7
8.2
193
1267
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
8.2
92
464
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
6.1
8.2
21
35
M10.9
ICD-10 Finland
Gout, unspecified
2.7
8.1
55
214
N25.0
ICD-10 Finland
Renal osteodystrophy
33.7
8.1
10
*
UJF32
NOMESCO Finland
Coloscopy
1.7
8.1
174
1110
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
7.4
8.0
18
25
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
8.0
494
5655
C09CA06
ATC
candesartan; oral
1.8
8.0
146
886
C10AA04
ATC
fluvastatin; oral
2.4
7.9
66
290
U14
ICPC
Kidney symptom/complaint
7.1
7.8
18
26
RD210
NOMESCO Finland
NA
5.4
7.7
22
42
C02CA01
ATC
prazosin; oral
5.7
7.7
21
38
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
7.7
70
320
M10.3
ICD-10 Finland
Gout due to impairment of renal function
18.6
7.6
11
6
RS220
NOMESCO Finland
NA
7.2
7.5
17
24
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
80.9
7.4
8
*
J01MA14
ATC
moxifloxacin; systemic
2.3
7.3
70
328
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
7.3
114
653
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
7.3
7
*
N04.4
ICD-10 Finland
Nephrotic syndrome, diffuse endocapillary proliferative glomerulonephritis
+∞
7.3
7
*
U88
ICPC
Glomerulonephritis/nephrosis
+∞
7.3
7
*
B01AB10
ATC
tinzaparin; parenteral
2.6
7.3
53
216
B01AC04
ATC
clopidogrel; oral
1.9
7.3
108
608
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
30.3
7.2
9
*
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
7.1
34
107
5997A
ICD-9 Finland
Other disorders of urethra and urinary tract, Haematuria
12.2
7.1
12
10
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
7.1
161
1039
J01MA12
ATC
levofloxacin; systemic
1.8
7.0
133
813
A02BC02
ATC
pantoprazole; systemic
1.5
6.9
430
3551
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
11.1
6.8
12
11
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.6
6.8
29
84
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
40.4
6.8
8
*
N28.9
ICD-10 Finland
Disorder of kidney and ureter, unspecified
22.7
6.7
9
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.9
6.6
25
65
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
12.4
6.6
11
9
C07AG02
ATC
carvedilol; oral
2.6
6.6
46
184
ZX108
NOMESCO Finland
Inhalation
8.8
6.6
13
15
R60.1
ICD-10 Finland
Generalized oedema
10.1
6.5
12
12
ZXA00
NOMESCO Finland
Right side
1.6
6.5
171
1148
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.7
6.5
42
162
A12BA01
ATC
potassium chloride; oral
3.0
6.3
33
112
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
2.1
6.3
70
353
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
+∞
6.3
6
*
N08.2*D89.82
ICD-10 Finland
Nepropathy caused by deposition of the light chain of the immunoglobulins
+∞
6.3
6
*
N04.5
ICD-10 Finland
Nephrotic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
6.3
6
*
N00
ICD-10 Finland
Acute nephritic syndrome
+∞
6.3
6
*
N04.89
ICD-10 Finland
Nephrotic syndrome, other
+∞
6.3
6
*
N03.7
ICD-10 Finland
Chronic nephritic syndrome, diffuse crescentic glomerulonephritis
+∞
6.3
6
*
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
26.9
6.2
8
*
K65.0
ICD-10 Finland
Acute peritonitis
5.8
6.2
16
28
S97
ICPC
Chronic ulcer skin
2.7
6.2
40
154
C09AA05
ATC
ramipril; oral
1.6
6.1
165
1114
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
6.1
65
323
J01DB01
ATC
cefalexin; oral
1.5
6.0
555
4911
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.2
6.0
29
93
C10AA01
ATC
simvastatin; oral
1.5
6.0
276
2112

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
243
543
6.00
108.90
20.8
7.1
12.3
9.2
mmol/l
7.48
236
517
60
10
64.82
108.28
2.0
1.7
—
—
—
0
0
73
28
28.61
106.96
25.9
35.8
81.0
142.3
ug/l
4.31
65
23
197
429
5.78
89.50
11.8
3.8
129.9
76.7
ng/l
7.42
185
379
273
809
4.62
85.43
21.6
5.5
1.1
1.0
mmol/l
5.93
268
753
51
25
21.73
67.61
31.7
24.5
6.9
7.6
ug/l
0.61
43
20
111
263
4.74
44.20
2.9
1.4
12.9
7.1
u/ml
—
10
8
34
18
19.69
43.33
6.1
4.1
—
—
—
0
0
205
815
3.04
37.64
7.3
2.4
24.0
23.5
%
0.20
182
703
272
1281
2.71
36.14
6.0
2.4
3.1
5.3
e6/l
2.28
251
1130
58
97
6.37
33.71
7.6
2.6
—
—
—
0
0
97
260
4.11
32.66
2.5
1.9
1.5
1.5
g/l
0.38
89
228
335
1824
2.45
32.05
8.8
3.1
215.1
172.3
mg/l
0.25
295
1203
347
1926
2.42
31.73
10.1
3.8
39.3
6.1
mg/mmol
7.61
302
1246
352
1968
2.42
31.64
9.8
3.0
7.0
8.1
mmol/l
5.65
330
1652
104
303
3.80
31.11
13.0
4.4
23.4
24.2
mmol/l
1.57
94
272
323
1760
2.41
30.52
15.3
3.9
7.4
7.4
ph
0.63
60
336
154
591
2.99
29.52
13.1
3.9
1.1
2.0
mmol/l
2.07
126
475
40
52
8.05
29.14
2.5
2.6
—
—
—
0
0
458
2990
2.25
27.25
22.1
6.8
1.2
1.2
mmol/l
0.07
406
2535
26
20
13.41
27.24
3.1
3.6
—
—
—
0
0
82
226
3.93
26.44
9.7
3.6
0.9
0.2
g/l
2.21
58
97
325
1879
2.23
25.69
8.5
3.1
22.6
99.5
e6/l
1.50
287
1451
129
485
2.98
25.44
3.1
2.8
63.2
66.8
g/l
4.42
121
441
111
388
3.16
24.81
2.4
2.7
—
—
—
0
0
408
2611
2.16
24.65
15.0
4.9
34.4
35.7
g/l
4.96
399
2442
384
2406
2.15
24.44
3.8
2.2
75.9
76.2
nmol/l
0.08
368
2149
74
202
3.94
24.15
2.3
1.4
1.1
1.2
g/l
1.47
69
192
72
194
3.98
23.92
2.3
1.4
0.3
0.2
g/l
0.60
65
184
417
2712
2.13
23.91
18.3
6.3
1.2
1.2
mmol/l
0.55
401
2468
232
1197
2.32
23.79
6.5
2.7
481.1
573.1
mosm/kgh2o
11.66
209
1026
60
142
4.49
23.64
2.6
1.4
—
—
—
0
0
57
131
4.61
23.29
3.0
1.4
132.3
107.3
u/ml
—
9
25
293
1681
2.18
23.07
5.3
2.7
386.3
7063.3
umol/l
6.24
276
1469
296
1714
2.16
22.69
8.0
3.0
0.2
0.4
e6/l
1.98
259
1292
288
1659
2.15
22.29
7.6
3.0
—
—
—
0
0
129
520
2.77
22.22
15.7
9.4
—
—
—
0
0
159
718
2.52
21.75
3.3
1.6
—
—
—
0
0
58
143
4.30
21.68
1.9
1.3
281.5
264.6
u/ml
0.14
41
84
203
1056
2.24
19.97
5.9
2.7
0.5
1.0
e6/l
3.72
150
621
246
1384
2.13
19.84
6.6
3.4
—
—
—
0
0
37
68
5.66
19.47
1.1
1.3
—
—
—
0
0
343
2190
2.00
19.46
10.1
3.6
44.5
92.9
e6/l
1.17
293
1561
148
689
2.41
18.76
4.4
2.8
1.8
1.8
%
0.17
143
623
325
2072
1.96
18.21
8.5
6.1
—
—
—
0
0
191
1004
2.19
18.12
5.8
3.7
0.8
0.8
mmol/l
2.09
185
951
37
73
5.27
18.04
2.2
2.5
—
—
—
0
0
44
103
4.46
17.55
2.3
1.3
—
—
—
0
0
431
3052
1.90
17.29
9.4
4.5
0.0
0.0
estimate
0.50
83
584
183
969
2.15
16.92
3.2
2.5
29.5
29.8
s
0.36
176
942
432
3090
1.87
16.51
7.0
3.4
0.0
0.0
estimate
0.50
82
559
48
127
3.96
16.32
3.1
4.6
—
—
—
0
0
427
3051
1.86
16.29
7.0
3.3
0.0
0.0
estimate
0.00
78
575
21
7
30.76
16.17
10.8
13.9
4.8
6.9
mmol/l
—
21
7
115
509
2.47
16.16
4.8
2.8
71.2
69.9
e9/l
0.14
78
402
58
178
3.44
15.89
3.4
4.2
42.5
32.3
mg/l
0.70
43
146
58
178
3.44
15.89
3.4
4.2
64.6
87.5
mg/l
0.27
43
143
67
226
3.15
15.76
1.7
1.3
—
—
—
0
0
17
16
10.84
15.58
1.0
1.0
—
—
—
0
0
170
911
2.10
15.08
2.9
2.0
—
—
—
0
0
20
25
8.18
14.94
1.1
1.1
—
—
—
0
0
20
25
8.18
14.94
1.1
1.0
—
—
—
0
0
440
3229
1.81
14.86
9.4
6.3
0.2
0.2
e9/l
0.03
402
2878
180
996
2.04
14.61
6.8
2.9
1.3
1.8
e6/l
0.58
127
564
166
894
2.08
14.48
3.3
1.6
—
—
—
0
0
428
3136
1.79
14.33
9.4
5.9
0.0
0.0
e9/l
0.03
391
2739
268
1715
1.85
14.03
7.5
4.3
—
—
—
0
0
425
3120
1.78
14.02
9.4
5.9
0.6
0.6
e9/l
1.32
390
2715
434
3215
1.77
13.79
9.6
6.0
1.8
1.9
e9/l
1.46
396
2862
45
134
3.50
12.92
6.2
4.1
—
—
—
0
0
107
506
2.29
12.86
7.7
3.1
—
—
—
0
0
187
1096
1.92
12.69
3.3
1.8
—
—
—
0
0
470
3628
1.72
12.31
12.8
9.4
4.4
4.1
e9/l
1.93
431
3192
101
489
2.22
11.44
4.1
2.7
9.3
10.8
g/l
2.21
94
447
392
2933
1.66
11.09
10.0
6.1
2.8
2.9
%
0.54
383
2751
40
122
3.40
11.08
1.5
1.8
—
—
—
0
0
394
2955
1.66
11.02
10.2
6.4
8.6
8.7
%
0.11
385
2789
41
128
3.32
10.96
7.0
3.0
—
—
—
0
0
29
71
4.20
10.95
1.4
1.2
—
—
—
0
0
89
421
2.25
10.65
9.2
3.5
7.4
7.4
ph
0.04
19
52
380
2845
1.64
10.55
10.0
6.2
0.7
0.7
%
0.00
373
2676
395
2991
1.64
10.44
9.9
6.0
59.1
57.2
%
2.44
388
2831
399
3042
1.63
10.16
9.8
6.2
26.3
27.9
%
2.14
389
2859
48
174
2.87
9.98
4.5
3.5
—
—
—
0
0
130
734
1.92
9.67
2.4
1.6
—
—
—
0
0
140
817
1.87
9.40
1.4
1.3
487.1
462.6
titre
0.05
28
163
495
4027
1.61
9.27
6.9
4.1
93.1
1781.9
e6/l
—
8
59
12
5
24.32
8.93
5.7
3.6
—
—
—
0
0
113
625
1.94
8.91
6.6
9.3
95.2
95.5
%
0.21
106
602
353
2673
1.58
8.85
6.0
2.7
197.4
141.5
ug/l
3.52
336
2475
23
56
4.20
8.76
5.2
4.7
10.7
10.4
%
0.13
23
56
43
162
2.75
8.35
8.2
3.1
9.2
8.4
kpa
1.71
43
144
86
447
2.04
8.08
2.3
1.5
—
—
—
0
0
36
126
2.95
8.00
4.5
2.6
16.5
16.1
%
0.24
25
67
240
1699
1.59
7.82
3.9
2.9
—
—
—
0
0
76
383
2.09
7.75
6.7
7.9
23.9
24.6
mmol/l
0.53
70
354
511
4279
1.54
7.69
10.1
4.0
—
—
—
0
0
35
125
2.88
7.52
3.6
2.3
128.8
131.6
g/l
0.27
30
95
221
1549
1.59
7.46
9.7
7.0
—
—
—
0
0
101
572
1.88
7.39
6.6
9.9
116.6
122.2
g/l
1.68
95
549
117
694
1.80
7.38
6.7
8.8
0.9
1.2
mmol/l
0.19
84
542
23
64
3.67
7.34
1.4
1.2
170.0
212.0
titre
—
5
10
42
168
2.58
7.29
5.5
2.6
23.4
24.6
mmol/l
0.95
42
144
559
4805
1.55
7.21
13.4
7.7
77.8
78.4
u/l
0.09
540
4509
328
2527
1.51
7.15
11.6
8.9
1.2
1.2
inr
0.30
89
751
100
581
1.82
6.74
2.5
2.2
337.6
374.5
nmol/l
0.96
92
540
35
133
2.71
6.72
7.3
3.4
2.5
2.4
mmol/l
0.11
22
83
75
398
1.98
6.65
2.2
1.6
1.1
1.5
g/l
1.10
68
366
32
117
2.81
6.61
5.2
2.4
—
—
—
0
0
55
262
2.18
6.49
2.5
1.8
—
—
—
0
0
253
1889
1.50
6.24
2.3
2.1
215.4
298.4
u/l
0.47
241
1782
62
315
2.05
6.21
11.1
3.6
—
—
—
0
0
225
1643
1.52
6.16
7.9
3.6
0.0
0.0
estimate
0.80
75
571
21
63
3.40
6.03
1.1
1.1
—
—
—
0
0
211
1526
1.52
6.03
2.8
2.2
3.1
3.1
mg/l
0.02
187
1300
14
31
4.58
6.00
1.8
1.7
—
—
—
0
0
27
95
2.91
5.99
2.0
1.5
0.8
0.7
g/l
0.16
20
71
217
1583
1.51
5.94
6.2
4.2
96.6
89.4
%
3.58
210
1550
350
2807
1.44
5.89
17.4
9.6
0.0
0.0
e9/l
0.35
301
2323
14
32
4.44
5.78
1.6
1.2
—
—
—
0
0
72
396
1.90
5.77
4.9
5.7
—
—
—
0
0
23
76
3.09
5.68
1.1
1.1
—
—
—
0
0
257
1956
1.46
5.65
3.2
2.6
60.9
56.6
u/l
0.51
236
1814
200
1449
1.51
5.62
1.7
1.5
19.3
20.2
nmol/l
0.39
188
1237
16
42
3.87
5.56
6.3
4.8
—
—
—
0
0
30
117
2.63
5.52
2.3
1.2
—
—
—
0
0
82
477
1.80
5.51
12.9
3.3
1.2
1.2
mmol/l
0.55
74
419
50
246
2.10
5.47
2.7
1.8
5.9
2.5
ug/l
0.63
45
220
96
587
1.72
5.44
2.3
2.7
0.2
0.2
g/l
1.24
91
548
261
2013
1.44
5.29
5.9
3.3
2.3
2.3
mmol/l
1.29
248
1756
11
22
5.06
5.27
1.5
1.0
1125.7
1515.6
miu/ml
0.58
11
22
88
530
1.74
5.26
5.3
4.6
1.1
1.0
%
0.20
34
160
17
49
3.52
5.19
1.6
1.4
—
—
—
0
0
14
35
4.05
5.18
4.6
1.9
524.5
479.0
min
1.03
14
24
81
481
1.76
5.09
4.8
4.4
0.6
0.5
%
0.22
27
120
18
55
3.33
5.05
1.1
1.1
—
—
—
0
0
27
105
2.63
5.01
1.5
1.3
—
—
—
0
0
389
3244
1.39
4.96
6.6
6.7
10.1
11.7
umol/l
2.42
370
3080
14
37
3.83
4.83
1.2
1.6
—
—
—
0
0
82
497
1.72
4.80
5.2
4.8
0.1
0.2
%
0.09
35
144
18
58
3.15
4.66
5.7
4.4
—
—
—
0
0
78
471
1.73
4.63
5.4
4.7
0.0
0.2
%
0.87
29
125
7
5
14.11
4.58
1.4
1.2
—
—
—
0
0
437
3744
1.37
4.57
8.1
5.0
6.8
6.7
mmol/l
0.67
421
3501
182
1350
1.45
4.44
7.3
3.6
1.0
1.0
kg/l
0.11
24
176
36
171
2.16
4.35
3.9
2.2
250.0
65.2
ug/min
1.21
25
101
152
1104
1.47
4.12
1.9
1.7
1422.7
1179.5
nmol/l
1.89
130
839
46
252
1.88
3.79
8.0
4.7
—
—
—
0
0
9
16
5.68
3.66
1.0
1.3
—
—
—
0
0
11
30
3.70
3.65
1.0
1.5
134.5
139.3
nmol/l
0.14
11
30
80
522
1.59
3.56
1.5
1.4
—
—
—
0
0
345
2932
1.31
3.46
5.7
4.1
—
—
—
0
0
16
58
2.79
3.43
1.8
1.3
2669.5
33203.0
e6/l
—
10
31
108
761
1.49
3.40
1.7
1.4
—
—
—
0
0
511
4617
1.30
3.09
6.3
4.0
19.1
11.2
mm/h
13.12
491
4268
15
56
2.71
3.07
1.5
1.3
443534.0
188819.6
e6/l
—
10
43
15
56
2.71
3.07
2.6
2.2
—
39.4
—
0
7
194
2395
0.75
3.06
3.2
2.7
—
—
—
0
0
16
62
2.61
3.06
1.4
1.2
—
—
—
0
0
14
51
2.78
3.00
1.2
1.2
—
—
—
0
0
18
76
2.40
2.91
1.4
1.5
—
—
—
0
0
18
76
2.40
2.91
1.4
1.5
—
—
—
0
0
18
76
2.40
2.91
1.4
1.5
—
—
—
0
0
18
76
2.40
2.91
1.4
1.5
—
—
—
0
0
55
345
1.64
2.91
1.3
1.2
—
—
—
0
0
221
1808
1.31
2.83
3.5
3.1
6203.4
1236.9
ng/l
3.04
198
1547
13
47
2.80
2.82
1.7
1.4
33.7
25.0
%
0.44
13
34
290
2462
1.28
2.79
2.0
2.0
96.4
94.5
pmol/l
0.27
156
1332
5
6
8.38
2.75
1.2
1.2
—
—
—
0
0
51
321
1.63
2.68
9.1
13.0
—
—
—
0
0
16
68
2.38
2.57
2.9
2.2
34.2
33.5
pg
0.36
16
68
179
1441
1.31
2.55
6.4
4.6
—
—
—
0
0
5
7
7.18
2.55
3.4
1.0
—
—
—
0
0
5
7
7.18
2.55
3.4
1.0
—
—
—
0
0
5
7
7.18
2.55
3.4
1.0
—
—
—
0
0
6
11
5.49
2.54
1.7
1.1
—
—
—
0
0
13
50
2.63
2.54
1.2
1.2
5.8
7.2
g/l
—
8
34
13
50
2.63
2.54
1.2
1.2
2.4
2.9
g/l
—
8
34
13
50
2.63
2.54
1.2
1.2
0.3
0.4
g/l
—
8
32
34
195
1.78
2.50
4.6
8.2
1.2
1.2
mmol/l
0.36
27
171
20
95
2.13
2.50
1.5
1.3
52.3
60.0
mmol/l
0.46
15
85
7
16
4.40
2.48
1.3
1.9
—
—
—
0
0
25
131
1.94
2.43
3.6
2.1
—
—
—
0
0
6
177
0.33
2.42
1.0
1.6
—
—
—
0
0
43
267
1.65
2.40
3.1
2.8
—
—
—
0
0
9
27
3.36
2.39
1.6
1.3
—
—
—
0
0
14
58
2.44
2.38
2.6
1.4
—
—
—
0
0
21
105
2.03
2.32
1.4
1.9
—
—
—
0
0
282
2429
1.25
2.32
4.6
3.6
74.9
39.4
ng/l
0.55
207
1687
18
85
2.14
2.30
1.4
1.4
—
—
—
0
0
158
1272
1.30
2.25
1.6
1.7
464.5
21428995.5
pmol/l
0.97
139
1064
670
6372
1.33
2.23
30.2
13.9
23.0
24.4
mg/l
0.58
573
5026
100
754
1.37
2.21
2.7
3.2
11.0
8.3
umol/l
0.47
85
659
23
122
1.91
2.18
4.8
3.5
3.7
4.3
e9/l
0.65
23
122
23
124
1.88
2.09
5.5
4.0
53.2
58.0
%
1.00
23
124
5
10
5.02
2.07
1.2
1.2
—
—
—
0
0
75
545
1.42
2.07
2.7
2.4
3.9
7.7
ug/l
4.33
67
490
182
1510
1.27
2.04
3.5
2.4
—
—
—
0
0
232
1991
1.23
1.92
3.7
2.4
—
—
—
0
0
13
58
2.26
1.91
7.5
3.0
64.0
35.0
mg/l
0.47
13
44
126
1007
1.30
1.90
1.2
1.3
28.3
34.1
iu/ml
0.39
41
306
38
245
1.58
1.87
4.2
2.8
21.4
21.5
s
0.05
33
223
17
315
0.53
1.87
1.2
1.6
—
—
—
0
0
11
46
2.41
1.86
1.1
1.4
—
—
—
0
0
14
66
2.14
1.82
5.6
6.2
7.9
6.9
mmol/l
0.48
14
54
14
67
2.11
1.76
2.1
2.3
—
—
—
0
0
7
24
2.93
1.72
1.3
1.1
—
—
—
0
0
480
4455
1.20
1.69
4.5
3.8
—
—
—
0
0
28
173
1.64
1.66
1.4
1.5
263.4
282.9
ug/g
0.16
20
107
614
5841
1.22
1.62
7.3
5.7
39.8
39.8
mmol/mol
0.01
590
5448
12
56
2.16
1.61
1.5
2.2
1.3
1.2
e9/l
—
7
28
42
288
1.48
1.61
2.5
2.4
—
—
—
0
0
46
322
1.45
1.59
9.0
11.2
23.2
24.5
mmol/l
1.48
41
302
27
170
1.61
1.50
1.4
1.1
—
—
—
0
0
164
1392
1.22
1.49
2.3
1.8
1.7
1.2
mg/l
0.94
134
1060
192
1658
1.21
1.47
2.0
1.7
1.5
1.4
mmol/l
0.65
169
1404
15
80
1.89
1.45
2.1
4.7
—
—
—
0
0
29
188
1.56
1.44
1.1
1.4
149.3
250.4
miu/ml
—
10
88
562
5325
1.19
1.43
33.9
16.9
13.9
13.6
%
5.23
555
5228
18
103
1.76
1.41
1.1
1.2
7.0
6.0
u/ml
—
7
46
9
41
2.21
1.37
1.0
1.0
—
—
—
0
0
70
543
1.32
1.35
2.4
1.7
—
—
—
0
0
138
1618
0.82
1.30
2.5
2.9
0.8
0.8
ug/l
0.06
94
1038
8
34
2.37
1.29
1.1
1.2
7.9
6.1
ug/l
—
8
28
674
6517
1.22
1.26
35.4
16.0
139.5
139.7
mmol/l
1.23
665
6341
16
92
1.75
1.25
1.3
1.2
—
—
—
0
0
6
25
2.41
1.24
3.3
3.0
—
—
—
0
0
8
36
2.23
1.24
1.0
1.0
—
—
—
0
0
53
400
1.35
1.24
3.8
2.6
—
—
—
0
0
12
63
1.92
1.23
2.5
1.7
—
—
—
0
0
675
6533
1.22
1.22
36.6
16.1
4.1
4.0
mmol/l
8.12
665
6352
491
4638
1.15
1.17
3.9
3.7
15.0
14.7
pmol/l
1.52
467
4205
5
20
2.51
1.15
1.2
1.2
—
—
—
0
0
140
1203
1.20
1.14
5.6
3.8
489.8
431.5
ng/l
0.07
119
935
193
1706
1.17
1.14
6.6
3.0
—
—
—
0
0
7
30
2.34
1.12
1.9
1.7
—
—
—
0
0
66
524
1.28
1.11
9.5
3.5
—
—
—
0
0
56
436
1.31
1.09
1.4
1.4
—
—
—
0
0
7
33
2.13
1.05
1.3
1.1
333.2
154.5
iu/ml
—
7
33
141
1222
1.19
1.05
1.7
1.4
2.4
2.5
g/l
0.27
99
763
10
53
1.90
1.01
1.3
1.1
—
—
—
0
0
10
54
1.86
0.97
1.4
1.9
15.0
21.6
nmol/l
—
10
49
7
37
1.90
0.94
4.7
4.1
24.7
18.2
mu/l
—
7
37
8
44
1.83
0.86
1.0
1.2
—
—
—
0
0
17
112
1.53
0.85
1.2
1.1
—
—
—
0
0
111
963
1.18
0.84
1.3
1.3
14.2
10.2
u/ml
0.19
34
378
6
32
1.88
0.82
1.5
1.2
—
—
—
0
0
32
419
0.75
0.82
1.6
1.4
—
—
—
0
0
95
816
1.19
0.81
1.2
1.2
—
—
—
0
0
39
303
1.30
0.81
7.6
3.3
—
—
—
0
0
87
742
1.19
0.80
2.7
2.5
167.1
119.2
ug/g
0.51
72
592
26
190
1.38
0.80
1.2
1.1
—
—
—
0
0
34
438
0.77
0.78
4.1
2.7
3.8
4.1
e9/l
0.33
29
356
0
27
0.00
0.77
0.0
13.8
—
—
—
0
0
598
6156
0.88
0.77
5.3
4.4
6.0
6.0
mmol/l
0.03
563
5646
79
674
1.19
0.74
1.4
1.3
—
—
—
0
0
9
55
1.64
0.73
1.0
1.3
—
—
—
0
0
22
298
0.73
0.72
1.1
1.1
—
—
—
0
0
19
134
1.43
0.72
1.5
1.3
3.9
12.0
e6/l
0.80
14
107
19
134
1.43
0.72
1.6
1.4
355.1
1445.5
e6/l
0.57
14
110
16
109
1.48
0.71
1.9
1.1
—
—
—
0
0
16
109
1.48
0.71
1.9
1.1
—
—
—
0
0
645
6301
1.13
0.64
5.7
4.4
4.5
4.6
mmol/l
3.33
615
5850
5
29
1.73
0.64
2.2
1.2
5.4
6.6
mmol/l
—
5
29
13
87
1.50
0.63
2.7
2.9
—
—
—
0
0
17
121
1.41
0.62
1.4
1.1
—
—
—
0
0
10
63
1.59
0.62
2.4
1.8
—
—
—
0
0
70
606
1.17
0.58
2.0
2.3
11.9
13.5
nmol/l
0.92
60
545
32
396
0.80
0.57
1.3
1.2
52.9
141.5
iu/ml
1.70
12
153
620
6056
1.11
0.57
5.1
3.9
1.4
1.3
mmol/l
2.35
590
5576
6
38
1.58
0.54
3.2
2.2
1.4
3.4
ug/l
—
6
33
14
99
1.42
0.54
2.6
1.4
—
—
—
0
0
9
63
1.43
0.52
1.4
1.2
—
—
—
0
0
9
63
1.43
0.52
1.1
1.5
—
—
—
0
0
31
377
0.82
0.49
1.1
1.2
—
—
—
0
0
12
166
0.72
0.48
1.2
1.2
—
—
—
0
0
16
120
1.34
0.46
1.1
1.4
—
—
—
0
0
57
651
0.87
0.46
1.4
1.4
—
—
—
0
0
11
153
0.72
0.46
1.5
1.7
621.6
6.2
iu/l
—
5
48
5
83
0.60
0.46
1.2
1.1
—
—
—
0
0
13
175
0.74
0.45
1.6
1.9
169.5
215.5
pmol/l
1.45
13
166
677
6668
1.10
0.43
27.3
12.9
—
—
—
0
0
5
31
1.62
0.43
1.6
1.1
—
—
—
0
0
651
6401
1.09
0.43
6.0
4.8
2.6
2.8
mmol/l
4.39
619
5907
67
596
1.14
0.42
15.9
3.9
—
—
—
0
0
0
16
0.00
0.41
0.0
2.1
—
15.9
—
0
16
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
7
103
0.68
0.39
2.0
1.4
—
—
—
0
0
7
103
0.68
0.39
2.0
1.4
—
—
—
0
0
13
97
1.35
0.39
1.0
1.2
—
—
—
0
0
7
105
0.66
0.39
2.1
1.5
—
—
—
0
0
9
67
1.35
0.38
3.2
2.6
—
—
—
0
0
9
68
1.33
0.37
2.3
1.3
—
—
—
0
0
19
152
1.26
0.37
1.4
1.4
453.3
468.8
mg/l
0.09
19
144
17
134
1.27
0.37
1.5
1.3
4.0
3.7
mmol/l
0.83
17
126
264
2750
0.94
0.34
4.3
4.8
4.2
2.4
ug/l
0.61
235
2470
253
2425
1.06
0.33
2.2
2.0
—
—
—
0
0
15
188
0.79
0.33
6.3
2.2
—
—
—
0
0
68
620
1.11
0.31
3.9
4.6
24.4
25.7
ug/l
0.02
53
524
707
7136
0.92
0.30
41.6
20.4
131.5
137.3
g/l
16.95
702
7026
7
55
1.28
0.30
1.0
1.1
—
—
—
0
0
707
7135
0.92
0.29
41.5
20.3
7.0
6.7
e9/l
3.21
694
6944
707
7133
0.92
0.28
41.4
20.3
4.4
4.5
e12/l
12.37
696
6944
577
5680
1.06
0.28
4.5
4.4
2.0
2.3
mu/l
0.58
551
5193
634
6258
1.06
0.28
5.7
4.3
1.4
1.4
mmol/l
1.89
605
5775
707
7132
0.92
0.28
41.2
20.2
30.3
30.4
pg
0.48
702
7023
8
64
1.25
0.27
1.1
2.0
—
—
—
0
0
707
7131
0.92
0.27
41.3
20.3
91.3
90.9
fl
1.13
702
7024
117
1103
1.07
0.26
3.7
3.1
2.5
2.4
mmol/l
0.23
107
967
10
77
1.30
0.26
1.3
1.4
—
0.4
—
0
8
707
7129
0.93
0.26
41.6
20.3
249.9
246.2
e9/l
0.80
698
6952
9
74
1.22
0.25
1.7
1.4
—
—
—
0
0
17
202
0.84
0.25
1.3
1.6
—
—
—
0
0
41
454
0.90
0.24
1.1
1.2
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
—
5.1
—
0
10
21
242
0.86
0.22
6.8
1.9
—
—
—
0
0
64
595
1.08
0.21
1.4
1.4
—
—
—
0
0
21
241
0.87
0.21
5.0
2.0
—
—
—
0
0
685
6792
1.06
0.21
16.8
10.3
24.9
27.6
u/l
5.50
672
6571
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
5.4
—
—
—
0
0
33
297
1.12
0.20
1.1
1.1
—
78.7
—
0
7
21
240
0.87
0.20
4.5
1.9
—
—
—
0
0
21
240
0.87
0.20
4.9
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
6
50
1.20
0.19
1.2
1.2
—
—
—
0
0
14
164
0.85
0.18
7.0
4.2
—
—
—
0
0
10
121
0.82
0.18
4.3
2.8
0.9
0.9
nmol/l
—
10
100
21
237
0.88
0.18
1.7
1.8
33.1
40.4
nmol/l
1.20
21
229
18
157
1.15
0.17
5.3
3.1
—
—
—
0
0
27
243
1.12
0.17
1.0
1.1
—
—
—
0
0
7
63
1.11
0.17
1.3
1.7
—
—
—
0
0
130
1351
0.95
0.17
1.2
1.3
1.2
1.6
u/ml
0.38
39
393
5
69
0.72
0.17
1.6
1.4
—
—
—
0
0
174
1794
0.96
0.16
1.6
1.4
—
—
—
0
0
18
203
0.88
0.15
21.9
11.1
—
—
—
0
0
20
179
1.12
0.14
1.1
1.1
—
—
—
0
0
5
44
1.14
0.10
1.2
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.7
1.0
1.0
g/l
—
5
46
68
706
0.96
0.09
1.4
1.7
—
—
—
0
0
21
226
0.93
0.08
5.0
2.1
—
—
—
0
0
10
88
1.14
0.08
4.9
2.5
—
—
—
0
0
7
67
1.05
0.08
1.0
1.3
—
—
—
0
0
8
74
1.08
0.07
1.4
1.4
—
—
—
0
0
7
82
0.85
0.07
3.3
3.0
—
—
—
0
0
7
85
0.82
0.07
3.0
3.4
55.1
26.9
u/ml
—
7
85
63
644
0.98
0.04
1.5
1.4
—
—
—
0
0
11
101
1.09
0.04
1.5
3.0
8.3
43.3
u/ml
0.42
11
94
79
804
0.98
0.03
1.3
1.3
—
—
—
0
0
15
141
1.07
0.03
3.0
3.8
24.6
27.6
mg/l
—
5
94
10
107
0.93
0.02
1.3
1.2
—
—
—
0
0
10
106
0.94
0.01
9.1
3.0
—
—
—
0
0
15
144
1.04
0.00
1.5
1.4
—
—
—
0
0
41
404
1.02
0.00
1.3
1.3
—
48.5
—
0
27
589
5884
1.00
0.00
28.6
14.8
39.1
40.3
%
2.60
417
4333
25
255
0.98
0.00
1.3
1.2
—
—
—
0
0
11
113
0.97
0.00
1.1
1.1
0.1
2.6
u/ml
—
5
48
12
118
1.02
0.00
1.3
1.3
—
—
—
0
0
182
1816
1.00
0.00
4.8
3.8
—
—
—
0
0
5
50
1.00
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
191.3
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
40.3
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_ACUTENEPHRITIC and mortality.

Females

Parameter HR [95% CI] p-value
N14_ACUTENEPHRITIC 2.352 [1.85, 2.99] < 0.001
Birth year 0.997 [0.99, 1.01] 0.542

During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 1006 females with N14_ACUTENEPHRITIC died.

Males

Parameter HR [95% CI] p-value
N14_ACUTENEPHRITIC 2.225 [1.81, 2.73] < 0.001
Birth year 0.991 [0.98, 1.0] 0.05

During the follow-up period (1.1.1998 — 31.12.2019), 333 out of 1234 males with N14_ACUTENEPHRITIC died.

Mortality risk

Mortality risk for people of age

years, who have N14_ACUTENEPHRITIC.

N-year risk Females Males
1 0.177% 0.529%
5 1.543% 3.105%
10 3.692% 7.535%
15 6.689% 13.671%
20 11.881% 22.28%

Relationships between endpoints

Index endpoint: N14_ACUTENEPHRITIC – Acute nephritic syndrome

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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