Barrett oesophagus

K11_BARRET

Barrett's esophagus: Esophageal lesion lined with columnar metaplastic epithelium which is flat or villiform. Barrett epithelium is characterized by two different types of cells: goblet cells and columnar cells. The symptomatology of Barrett esophagus is that of gastro-esophageal reflux. It is the precursor of most esophageal adenocarcinomas. (WHO)

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K22.7
  • Hospital discharge: ICD-9 5301B
  • Cause of death: ICD-10 K22.7
  • Cause of death: ICD-9 5301B

2 out of 7 registries used, show all original rules.

1901

4. Check minimum number of events

None

1901

5. Include endpoints

None

1901

6. Filter based on genotype QC (FinnGen only)

1854

Control definitions (FinnGen only)

Control exclude
K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K22

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9000 3115 5865
Only index persons 8584 2996 5588
Unadjusted period prevalence (%)
Whole population 0.14 0.09 0.16
Only index persons 0.18 0.11 0.21
Median age at first event (years)
Whole population 66.17 67.73 65.35
Only index persons 66.10 67.56 65.32

-FinnGen-

Key figures

All Female Male
Number of individuals 1854 661 1193
Unadjusted period prevalence (%) 0.44 0.23 0.55
Median age at first event (years) 66.51 67.06 66.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1901
Matched controls
19010
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
124.0
307.7
931
146
K22.1
ICD-10 Finland
Ulcer of oesophagus
1098.3
307.7
491
6
K22.7
ICD-10 Finland
Barrett oesophagus
51294.8
307.7
1858
16
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
33.4
307.7
795
400
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
73.7
307.7
1708
2038
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
28.3
307.7
470
218
UJD02
NOMESCO Finland
Gastroscopy
16.7
292.9
256
175
A02BC05
ATC
esomeprazole; systemic
4.4
222.9
1127
4715
A02BC02
ATC
pantoprazole; systemic
5.1
160.9
1610
9933
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
20.6
155.9
120
62
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
244.3
154.6
157
7
K29.3
ICD-10 Finland
Chronic superficial gastritis
58.5
149.5
84
15
UJF30
NOMESCO Finland
Ileoscopy through colon
5.0
142.6
357
848
K20
ICD-10 Finland
Oesophagitis
32.5
139.0
90
29
A02BC03
ATC
lansoprazole; oral
3.2
126.8
741
3135
UJF32
NOMESCO Finland
Coloscopy
3.2
122.5
722
3059
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.4
119.8
262
551
K30
ICD-10 Finland
Functional dyspepsia
5.3
115.1
253
534
A02BC01
ATC
omeprazole; systemic
3.1
110.5
669
2850
UJC12
NOMESCO Finland
Flexible oesophagoscopy
26.9
108.9
75
29
A02BC04
ATC
rabeprazole; oral
4.9
107.6
261
598
K92.0
ICD-10 Finland
Haematemesis
12.1
99.7
102
89
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
24.3
95.1
68
29
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.8
94.7
756
3679
K29.7
ICD-10 Finland
Gastritis, unspecified
16.7
94.6
80
50
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
11.3
93.7
100
93
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.1
92.8
516
2068
D64.9
ICD-10 Finland
Anaemia, unspecified
3.7
90.2
331
1026
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
15.4
87.4
77
52
A02BA02
ATC
ranitidine; systemic
3.0
84.3
469
1869
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.1
79.0
397
1488
R13
ICD-10 Finland
Dysphagia
4.5
78.8
210
515
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
16.8
77.3
65
40
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
5.5
73.9
150
292
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
23.7
73.5
53
23
K22.2
ICD-10 Finland
Oesophageal obstruction
242.1
68.7
70
*
JCA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in oesophagus
333.1
64.9
65
*
K44
ICD-10 Finland
Diaphragmatic hernia
18.3
62.1
50
28
JCA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in oesophagus
+∞
61.8
59
*
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
18.8
57.9
46
25
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.7
55.2
192
567
WX002
NOMESCO Finland
Sedation and analgesia
2.4
54.9
479
2333
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.8
54.9
103
186
K92.1
ICD-10 Finland
Melaena
4.4
53.7
141
340
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
117.5
53.1
57
5
R12
ICD-10 Finland
Heartburn
3.6
52.3
182
537
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
50.9
1024
6883
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
50.8
515
2665
5301B
ICD-9 Finland
Diseases of oesophagus, Oesophagitis[BARRETT'S OESOPHAGUS]
+∞
50.2
48
*
D03
ICPC
Heartburn
5.4
48.0
98
191
6241
FHL
Fund application (Nissen)
437.3
43.4
43
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.1
40.7
184
637
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.9
39.6
120
321
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
38.9
593
3527
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
37.3
291
1328
R06.0
ICD-10 Finland
Dyspnoea
2.0
37.2
555
3269
N03AX16
ATC
[U] pregabalin
2.0
37.1
486
2732
K22.9
ICD-10 Finland
Disease of oesophagus, unspecified
132.7
36.8
39
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
36.8
465
2579
N02BE01
ATC
paracetamol; systemic, rectal
2.8
36.7
1732
14972
N06AX11
ATC
mirtazapine; oral
1.9
35.9
638
3976
D02
ICPC
Abdominal pain epigastric
3.5
35.6
125
370
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
35.2
537
3177
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
35.0
499
2884
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
34.6
315
1535
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
178.2
33.8
35
*
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
122.3
33.8
36
*
A03FA02
ATC
cisapride; oral, rectal
3.0
33.3
152
528
K22.4
ICD-10 Finland
Dyskinesia of oesophagus
173.0
32.8
34
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
32.3
864
6059
5301A
ICD-9 Finland
Diseases of oesophagus, Oesophagitis[OESOPHAGITIS REFLUENS]
+∞
31.3
30
*
M79.6
ICD-10 Finland
Pain in limb
1.8
30.6
779
5360
K29.8
ICD-10 Finland
Duodenitis
307.1
29.9
30
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
29.6
529
3266
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
29.5
255
1211
F10.25
ICD-10 Finland
Alcohol dependence continuous use
5.4
29.3
58
110
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
29.0
829
5867
K22.0
ICD-10 Finland
Achalasia of cardia
296.3
28.8
29
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.9
28.8
138
492
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
105.0
28.7
31
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
28.1
271
1345
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
285.6
27.8
28
*
AA1AD
NOMESCO Finland
CT of head and brain
1.8
27.6
572
3684
R11
ICD-10 Finland
Nausea and vomiting
2.7
27.4
159
628
UJD10, ,
SPAT
4.5
27.2
67
153
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
27.1
343
1882
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
26.9
266
1331
R03AC02
ATC
salbutamol; inhalant
1.7
26.4
957
7160
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.9
26.3
130
472
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
26.0
201
908
R53
ICD-10 Finland
Malaise and fatigue
1.9
25.8
409
2419
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
25.7
334
1848
T18.1
ICD-10 Finland
Foreign body in oesophagus
9.3
25.6
31
34
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
25.5
209
968
N06AB10
ATC
escitalopram; oral
2.0
25.3
330
1827
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
25.3
243
1202
JD1EE
NOMESCO Finland
Ultrasound examination of gastro-oesophageal reflux
30.5
25.0
33
11
N06AX21
ATC
duloxetine; oral
2.3
25.0
214
1010
WX402
NOMESCO Finland
General anaesthesia
1.8
24.8
428
2594
XG410
NOMESCO Finland
Flow-volume spirometry
3.2
24.4
97
310
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
24.4
382
2246
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
24.4
362
2092
J01MA02
ATC
ciprofloxacin; systemic
1.7
24.3
754
5383
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
7.4
24.2
35
48
A01
ICPC
Pain general/multiple sites
2.4
24.2
181
805
A02BA03
ATC
famotidine; systemic
3.6
24.0
81
233
JBC00
NOMESCO Finland
Gastro-oesophageal antireflux operation
+∞
24.0
23
*
D01
ICPC
Abdominal pain/cramps general
2.3
23.9
193
887
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
23.9
846
6237
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
23.9
377
2220
XJC10
NOMESCO Finland
Oesophageal pH monitoring
68.3
23.9
27
*
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
6.1
23.8
41
68
K29.1
ICD-10 Finland
Other acute gastritis
31.5
23.7
31
10
K31.7
ICD-10 Finland
Polyp of stomach and duodenum
87.9
23.7
26
*
SPAT1263
SPAT
Sampling
1.7
23.6
746
5339
N03AX12
ATC
[U] gabapentin; oral
1.9
23.5
321
1803
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
47.3
23.3
28
6
N05CF01
ATC
zopiclone; oral
1.7
23.2
587
3961
L17
ICPC
Foot/toe symptom/complaint
1.7
23.2
536
3530
WX704
NOMESCO Finland
Intubation
2.4
23.1
175
782
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
4.7
23.0
53
115
R02
ICPC
Shortness of breath/dyspnoea
2.1
22.9
255
1332
C03CA01
ATC
furosemide; systemic
1.7
22.7
571
3844
H02AB06
ATC
prednisolone; systemic
1.6
22.7
877
6582
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
22.6
340
1968
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
22.6
1289
10631
P15
ICPC
Chronic alcohol abuse
3.5
22.4
79
234
N05AH04
ATC
quetiapine; oral
1.9
22.3
297
1652
A04
ICPC
Weakness/tiredness general
2.0
22.1
249
1305
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
+∞
21.9
21
*
R51.80
ICD-10 Finland
Headache
2.1
21.9
243
1266
N07BB01
ATC
disulfiram; oral
2.9
21.8
106
381
R63.4
ICD-10 Finland
Abnormal weight loss
3.2
21.7
90
295
WX892
NOMESCO Finland
Monitored bed care
2.3
21.5
173
793
P03
ICPC
Feeling depressed
2.6
21.4
131
530
P01AB01
ATC
metronidazole; oral, rectal
1.6
21.4
670
4757
N06AX16
ATC
venlafaxine; oral
2.1
21.2
232
1202
Z01.2
ICD-10 Finland
Dental examination
1.6
21.1
765
5621
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
21.1
573
3920
R03BB04
ATC
tiotropium bromide; inhalant
2.1
21.1
210
1050
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
20.8
356
2142
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
5.8
20.7
38
67
JCA98
NOMESCO Finland
Other local endoscopic operation on oesophagus
77.7
20.7
23
*
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.4
20.7
155
689
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
20.6
657
4675
J01DB01
ATC
cefalexin; oral
1.7
20.5
1517
13190
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
20.5
989
7754
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
20.4
476
3125
B80
ICPC
Iron deficiency anaemia
4.5
20.4
50
114
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
20.3
342
2047
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
20.2
743
5463
N05BA04
ATC
oxazepam; oral
1.7
20.2
427
2730
S18
ICPC
Laceration/cut
1.6
20.0
897
6900
D50.8
ICD-10 Finland
Other iron deficiency anaemias
5.5
19.8
38
70
JN4AD
NOMESCO Finland
Body CT examination
2.0
19.7
233
1241
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
19.5
132
560
J01MA12
ATC
levofloxacin; systemic
1.8
19.5
361
2220
B01AB05
ATC
enoxaparin; parenteral
1.6
19.5
609
4301
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.8
19.3
100
372
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.9
19.3
91
322
R07.3
ICD-10 Finland
Other chest pain
2.1
19.1
193
970
J37.0
ICD-10 Finland
Chronic laryngitis
3.3
19.0
71
219
D11
ICPC
Diarrhoea
2.1
18.9
186
924
J01FF01
ATC
clindamycin; systemic
1.6
18.9
501
3391
SPAT1254
SPAT
Administration of medicine
1.9
18.9
261
1465
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
18.8
206
1066
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.7
18.8
102
389
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
+∞
18.8
18
*
5308A
ICD-9 Finland
Diseases of oesophagus, Other specified disorders of oesophagus[HERNIA HIATUS OESOPHAGI (""""SLIDING HERNIA"""")]
+∞
18.8
18
*
R4190
NOMESCO Finland
Nutritional therapy
3.0
18.8
83
283
A02BD07
ATC
lansoprazole, amoxicillin and clarithromycin; systemic
2.8
18.5
95
352
UJF92
NOMESCO Finland
Capsular endoscopy
4.5
18.3
44
99
UJC02
NOMESCO Finland
Rigid oesophagoscopy
7.5
18.3
26
35
XF402
NOMESCO Finland
ECG with work load test
2.0
18.1
219
1174
D50
ICD-10 Finland
Iron deficiency anaemia
4.4
18.1
45
104
M54.5
ICD-10 Finland
Low back pain
1.6
17.9
599
4280
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
17.8
202
1059
K59.09
ICD-10 Finland
Constipation, unspecified
2.3
17.7
134
599
J45
ICD-10 Finland
Asthma
2.1
17.6
171
845
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
17.5
1218
10192
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
4.2
17.5
46
111
N06AB04
ATC
citalopram; systemic
1.7
17.5
346
2162
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
17.5
485
3312
R07.0
ICD-10 Finland
Pain in throat
2.6
17.4
103
410
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.0
17.4
78
268
XG466
NOMESCO Finland
Sleep oxymetry
3.1
17.4
75
252
K44.0
ICD-10 Finland
Diaphragmatic hernia with obstruction, without gangrene
17.1
17.4
27
16
F10.24
ICD-10 Finland
Alcohol depence active use
4.5
17.3
42
95
D06
ICPC
Abdominal pain localized other
2.2
17.3
144
669
F10.20
ICD-10 Finland
Alcohol dependence currently independent
3.8
17.3
53
143
L03
ICPC
Low back symptom/complaint
1.6
17.3
454
3056
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.2
17.2
68
217
H02AB07
ATC
prednisone; oral
1.9
17.1
243
1375
8140/3-C15.9
ICD-O-3
Adenocarcinoma, NOS, of esophagus, NOS
31.8
17.0
22
7
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.4
17.0
61
183
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
3.0
16.9
76
262
N06AX12
ATC
bupropion; oral
2.6
16.8
100
399
L08
ICPC
Shoulder symptom/complaint
1.7
16.8
402
2641
C07AB07
ATC
bisoprolol; oral
1.5
16.6
941
7505
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
16.6
567
4059
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
16.4
167
840
K29.6
ICD-10 Finland
Other gastritis
23.3
16.4
23
10
TPH07
NOMESCO Finland
Cathetrisation of artery
1.9
16.3
232
1312
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
16.2
316
1963
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
5.5
16.2
31
57
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
4.8
16.1
36
76
R60.0
ICD-10 Finland
Localized oedema
1.9
16.1
237
1355
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
16.0
307
1897
A02BA04
ATC
nizatidine; systemic
2.3
16.0
130
598
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
13.7
16.0
27
20
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.6
15.9
95
380
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
15.9
275
1650
G47.3
ICD-10 Finland
Sleep apnoea
1.6
15.8
460
3165
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
+∞
15.6
15
*
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.7
15.6
84
319
M25.5
ICD-10 Finland
Pain in joint
1.6
15.6
523
3717
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
15.6
119
533
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
15.6
183
970
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.4
15.6
108
464
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.4
15.5
108
465
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
15.5
297
1835
R05
ICPC
Cough
1.6
15.4
403
2702
D10
ICPC
Vomiting
2.9
15.4
72
254
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
15.2
482
3378
R4110
NOMESCO Finland
Physiotherapy
1.6
15.2
512
3639
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
15.2
882
7023
XJC00
NOMESCO Finland
Oesophageal manometry
45.4
15.1
18
*
L28
ICPC
Limited function/disability (L)
1.7
14.9
319
2028
C01DA14
ATC
isosorbide mononitrate; oral
1.7
14.9
285
1757
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
14.9
241
1416
R03BA05
ATC
fluticasone; inhalant
1.7
14.8
285
1760
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
57.1
14.8
17
*
K22.8
ICD-10 Finland
Other specified diseases of oesophagus
57.1
14.8
17
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.1
14.8
61
200
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
14.7
177
945
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.7
14.7
318
2027
M70.6
ICD-10 Finland
Trochanteric bursitis
1.9
14.7
214
1218
R05
ICD-10 Finland
Cough
1.6
14.7
357
2347
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
+∞
14.6
14
*
GD1AD
NOMESCO Finland
Thorax CT examination
2.2
14.5
128
609
N05BA12
ATC
alprazolam; oral
2.0
14.5
176
944
R52.9
ICD-10 Finland
Pain, unspecified
2.0
14.4
168
887
WX320
NOMESCO Finland
Spinalanesthesy
1.6
14.4
456
3193
UKC02
NOMESCO Finland
Cystoscopy
1.7
14.3
329
2130
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
14.3
472
3332
G44.2
ICD-10 Finland
Tension-type headache
1.9
14.3
196
1094
WX725
NOMESCO Finland
Noninvasive ventilation
2.3
14.2
115
528
Z2221
NOMESCO Finland
Medical doctor
1.6
14.2
450
3147
L02
ICPC
Back symptom/complaint
2.0
14.1
157
816
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
14.1
334
2179
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
14.1
359
2386
N06AX26
ATC
vortioxetine; oral
2.3
14.0
106
473
M03BX02
ATC
tizanidine; oral
1.5
14.0
1072
8945
A06AD11
ATC
lactulose; oral
1.8
14.0
250
1511
A02BD03
ATC
lansoprazole, amoxicillin and metronidazole; systemic
2.2
14.0
117
545
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.9
13.9
183
1007
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.1
13.9
142
715
N05CF02
ATC
zolpidem; oral
1.7
13.9
293
1854
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
13.9
216
1254
A11
ICPC
Chest pain NOS
2.0
13.9
156
814
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
3.7
13.8
43
118
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.1
13.7
138
691
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.9
13.7
65
231
P01
ICPC
Feeling anxious/nervous/tense
2.2
13.7
116
544
SFA10
NOMESCO Finland
One-surface restoration
1.4
13.6
920
7487
K02.1
ICD-10 Finland
Caries of dentine
1.4
13.6
983
8100
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
13.3
655
5015
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.4
13.1
95
416
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.0
13.1
142
731
A07EA06
ATC
budesonide; oral, local oral
2.8
13.1
63
226
WVA20
NOMESCO Finland
Medicine administration
2.9
13.0
60
210
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
13.0
627
4775
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.0
13.0
57
194
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
4.2
13.0
34
82
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
10.1
13.0
25
25
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.5
13.0
84
350
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
9.4
13.0
26
28
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.9
13.0
160
862
R42
ICD-10 Finland
Dizziness and giddiness
1.6
12.9
383
2632
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.1
12.9
125
617
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
12.9
506
3696
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.5
12.8
84
352
J20
ICD-10 Finland
Acute bronchitis
1.9
12.8
172
953
XQ800
NOMESCO Finland
Prick test
2.2
12.7
105
487
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
12.7
227
1372
R96
ICPC
Asthma
1.9
12.7
166
912
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
4.3
12.7
32
75
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
32.2
12.6
16
5
M01AH05
ATC
etoricoxib; oral
1.4
12.6
1083
9155
N05CD07
ATC
temazepam; oral
1.8
12.5
202
1186
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
4.3
12.5
32
76
Z53.0
ICD-10 Finland
Procedure not carried out because of contraindication
24.5
12.5
17
7
E0000UV, ,
ATC
1.4
12.4
669
5194
N06AA09
ATC
amitriptyline; systemic
1.9
12.4
160
875
C08CA01
ATC
amlodipine; oral
1.4
12.4
745
5902
K29.4
ICD-10 Finland
Chronic atrophic gastritis
11.7
12.3
22
19
N01
ICPC
Headache
2.0
12.3
133
685
J01AA02
ATC
doxycycline; systemic
1.5
12.2
1394
12371
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.9
12.2
165
916
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
4.8
12.1
27
57
R03AK08
ATC
formoterol and beclometasone; inhalant
2.5
12.1
75
306
R06.2
ICD-10 Finland
Wheezing
2.4
12.1
82
349
JBB01
NOMESCO Finland
Laparoscopic repair of paraoesophageal hernia
11.1
12.0
22
20
J01CA04
ATC
amoxicillin; systemic
1.5
12.0
1393
12380
A02BX02
ATC
sucralfate; oral
2.7
11.9
63
238
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
47.0
11.9
14
*
JDA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in stomach or pylorus
47.0
11.9
14
*
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
11.9
458
3326
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.0
11.9
52
177
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
11.8
383
2680
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
5.4
11.8
23
43
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.9
11.8
149
810
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.0
11.7
51
173
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
16.5
11.7
18
11
W19
ICD-10 Finland
Unspecified fall
1.8
11.7
169
959
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
11.6
702
5547
SPAT1262
SPAT
Handing over of treatment supplies
1.6
11.6
341
2334
A03
ICPC
Fever
1.7
11.6
235
1468
JDA55
NOMESCO Finland
Endoscopic dilatation of stomach, pylorus or anastomosis of stomach
19.0
11.6
17
9
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
11.6
494
3658
F34.1
ICD-10 Finland
Dysthymia
2.8
11.6
58
213
A97
ICPC
No disease
1.6
11.5
300
1996
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.1
11.5
109
534
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
11.5
1205
10462
JBC91
NOMESCO Finland
Revision antireflux surgery, endoscopic suture repair
+∞
11.5
11
*
K26.3
ICD-10 Finland
Duodenal ulcer, acute without haemorrhage or perforation
120.7
11.4
12
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
11.4
284
1869
WX290
NOMESCO Finland
Other blockage of nerve
1.4
11.3
724
5770
D84
ICPC
Oesophagus disease
15.1
11.3
18
12
S29
ICPC
Skin symptom/complaint other
1.6
11.3
329
2247
K63.5
ICD-10 Finland
Polyp of colon
3.1
11.2
47
156
C10AA05
ATC
atorvastatin; oral
1.4
11.2
838
6859
JDA05
NOMESCO Finland
Endoscopic polypectomy in stomach or pylorus
17.1
11.2
17
10
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
11.2
217
1341
NF1AA
NOMESCO Finland
Hip X-ray examination
1.8
11.2
162
920
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.7
11.1
34
92
SPAT1257
SPAT
Teaching of medicine inhalation technique
2.5
11.1
69
282
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
11.1
213
1312
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.7
11.1
209
1281
SPAT1255
SPAT
Intravenous administration of medicine
1.9
11.1
131
696
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
3.5
11.0
37
107
N02BF01
ATC
gabapentin; oral
1.9
11.0
144
791
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
10.9
116
593
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
10.9
319
2179
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
10.9
766
6196
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
3.0
10.9
47
159
SPAT1097
SPAT
Recording of ECG
1.6
10.9
270
1776
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.0
10.8
125
658
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
3.3
10.8
41
128
A28
ICPC
Limited function/disability NOS
1.6
10.8
296
1991
R06AE07
ATC
cetirizine; oral
1.4
10.8
655
5163
M34.1
ICD-10 Finland
CR(E)ST syndrome
10.6
10.8
20
19
F32
ICD-10 Finland
Depressive episode
2.4
10.8
71
299
R01AD09
ATC
mometasone; nasal
1.4
10.7
686
5455
WX722
NOMESCO Finland
PEEP
2.1
10.7
98
474
D09
ICPC
Nausea
2.6
10.7
61
240
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
60.3
10.6
12
*
K03.66
ICD-10 Finland
Tooth plaque
1.9
10.6
125
663
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
10.6
480
3586
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.1
10.6
106
531
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
10.5
171
1004
L15
ICPC
Knee symptom/complaint
1.5
10.5
398
2870
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
10.5
186
1119
SPAT1310
SPAT
Counselling related to known health issue
1.4
10.5
531
4048
A04.8
ICD-10 Finland
Other specified bacterial intestinal infections
4.5
10.5
25
56
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
4.8
10.5
23
48
N05BA01
ATC
diazepam; systemic, rectal
1.7
10.5
208
1292
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.2
10.4
88
412
N05AA02
ATC
levomepromazine; systemic
2.4
10.4
74
322
53094
ICD-8 Finland
Diseases of oesophagus, Oesophagitis
+∞
10.4
10
*
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.5
10.4
67
279
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
10.4
231
1477
Z72.1
ICD-10 Finland
Alcohol use
3.9
10.4
30
78
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
10.4
108
548
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
10.4
117
611
R35
ICD-10 Finland
Polyuria
1.9
10.4
135
740
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
10.4
351
2473
K55.2
ICD-10 Finland
Angiodysplasia of colon
8.2
10.3
22
27
B82
ICPC
Anaemia other/unspecified
2.7
10.3
55
209
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
10.3
143
801
L01
ICPC
Neck symptom/complaint
1.6
10.2
224
1427
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
10.2
201
1245
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.8
10.2
146
825
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
10.2
172
1021
K59.1
ICD-10 Finland
Functional diarrhoea
2.2
10.2
88
416
C10AC01
ATC
colestyramine; oral
3.1
10.2
41
133
A98
ICPC
Health maint/preventive medicine
2.0
10.2
1810
17245
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.1
10.2
92
443
R74
ICPC
Upper respiratory infection acute
1.5
10.2
395
2862
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.9
10.2
46
160
SPAT1260
SPAT
Consultation of another employee
1.6
10.2
296
2019
F41.1
ICD-10 Finland
Generalized anxiety disorder
2.5
10.2
60
240
R52.0
ICD-10 Finland
Acute pain
2.7
10.1
55
211
E66.8
ICD-10 Finland
Other obesity
2.2
10.1
81
372
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.6
10.1
58
229
N07BA03
ATC
varenicline; oral
2.2
10.0
85
399
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
3.2
10.0
39
124
SPAT1265
SPAT
Breathalyser
4.6
10.0
23
50
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.2
10.0
84
393
R21
ICPC
Throat symptom/complaint
1.6
10.0
241
1573
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
10.0
140
787
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
9.9
350
2485
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
9.9
136
758
E66.01
ICD-10 Finland
Obesity due to excess calories
1.9
9.9
125
678
E87.6
ICD-10 Finland
Hypokalaemia
2.4
9.9
65
273
E61.1
ICD-10 Finland
Iron deficiency
4.2
9.9
26
63
N03AE01
ATC
clonazepam; systemic
2.1
9.9
97
482
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.9
9.9
127
694
Z02.7
ICD-10 Finland
Issue of medical certificate
1.9
9.9
115
608
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
9.9
150
864
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.4
9.9
65
274
PD5AD
NOMESCO Finland
CT of aorta
2.8
9.8
49
180
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
4.0
9.8
27
68
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
9.7
461
3466
SPAT1325
SPAT
Vaccination
1.4
9.7
570
4450
U02
ICPC
Urinary frequency/urgency
1.6
9.7
211
1341
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.5
9.7
404
2965
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.9
9.7
45
159
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.5
9.7
62
258
M01AB05
ATC
diclofenac; systemic, rectal
1.4
9.6
1159
10140
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
9.6
1064
9186
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.0
9.6
98
494
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.3
9.6
73
328
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.5
9.6
61
253
SPAT1153
SPAT
Removal of sutures
1.4
9.5
584
4590
R95
ICPC
Chron obstructive pulmonary disease
2.4
9.5
64
272
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
3.0
9.5
42
144
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
9.5
269
1821
N05AB01
ATC
dixyrazine; systemic
3.8
9.5
28
74
R03DC03
ATC
montelukast; oral
1.6
9.5
230
1503
WX882
NOMESCO Finland
High dependency care
2.6
9.4
55
219
C159, 8148, 2
ICD-O-3
+∞
9.4
9
*
K26.4
ICD-10 Finland
Duodenal ulcer, chronic or unspecified with haemorrhage
+∞
9.4
9
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.1
9.4
91
451
M01AH01
ATC
celecoxib; oral
1.5
9.4
295
2045
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
9.3
626
4991
N06AB06
ATC
sertraline; oral
1.8
9.3
153
901
G04CA02
ATC
tamsulosin; oral
1.4
9.3
521
4029
R01AD08
ATC
fluticasone; nasal
1.4
9.3
417
3100
WX419
NOMESCO Finland
Other general anesthesy
4.7
9.3
21
45
C07AA05
ATC
propranolol; systemic
1.5
9.3
290
2006
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.4
9.3
65
282
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
9.3
237
1568
P76
ICPC
Depressive disorder
2.1
9.2
81
386
C05AA08
ATC
fluocortolone; rectal, topical
1.6
9.2
224
1465
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.6
9.2
223
1457
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.0
9.1
105
553
L04
ICPC
Chest symptom/complaint
2.0
9.1
99
511
M54.6
ICD-10 Finland
Pain in thoracic spine
1.9
9.1
109
582
N17
ICPC
Vertigo/dizziness
1.6
9.1
196
1243
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
9.1
229
1509
A03CA02
ATC
clidinium and psycholeptics; oral
2.0
9.1
92
463
J02AC01
ATC
fluconazole; systemic
1.4
9.1
497
3827
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.5
9.1
54
217
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
2.5
9.1
55
223
C10AA01
ATC
simvastatin; oral
1.3
9.1
808
6727
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
9.1
108
576
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
9.1
390
2877
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
9.0
301
2113
H02AB04
ATC
methylprednisolone; systemic
1.6
9.0
217
1416
C09CA06
ATC
candesartan; oral
1.4
9.0
405
3013
R06AX27
ATC
desloratadine; oral
1.5
9.0
377
2768
N30.0
ICD-10 Finland
Acute cystitis
1.6
9.0
207
1336
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
8.9
122
680
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
8.9
215
1402
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
8.9
141
822
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.1
8.9
84
412
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.4
8.9
446
3382
R30.0
ICD-10 Finland
Dysuria
2.3
8.9
66
294
K90.0
ICD-10 Finland
Coeliac disease
2.7
8.9
45
167
SPAT1216
SPAT
Assessment of functional ability
1.5
8.9
260
1774
R03BA02
ATC
budesonide; inhalant
1.5
8.8
262
1791
ZXD05
NOMESCO Finland
Urgent procedure
1.4
8.8
472
3617
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
3.1
8.8
36
118
M02AA07
ATC
piroxicam; topical
1.4
8.8
602
4804
JAD10
NOMESCO Finland
Repair of incisional hernia
4.7
8.8
20
43
A46
ICD-10 Finland
Erysipelas
1.5
8.8
268
1843
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
8.8
498
3855
SGA01
NOMESCO Finland
Emergency treatment
1.6
8.7
243
1638
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
3.7
8.7
27
74
F39
ICD-10 Finland
Unspecified mood [affective] disorder
4.1
8.7
23
56
XKD00
NOMESCO Finland
Uroflowmetry
1.5
8.7
339
2453
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.4
8.7
417
3136
M50.3
ICD-10 Finland
Other cervical disc degeneration
2.7
8.7
45
169
B01AF02
ATC
apixaban; oral
1.6
8.7
242
1633
M01AE02
ATC
naproxen; oral, rectal
1.3
8.6
907
7719
SFA20
NOMESCO Finland
Two-surface restoration
1.3
8.6
955
8189
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
8.6
316
2258
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
8.6
424
3202
K05.1
ICD-10 Finland
Chronic gingivitis
1.9
8.6
102
543
NG2AA
NOMESCO Finland
Patella X-ray examination
2.5
8.6
53
217
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
8.6
483
3732
R01AD58
ATC
fluticasone, combinations; nasal
1.5
8.6
315
2251
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
8.6
445
3391
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
8.6
213
1399
P16
ICPC
Acute alcohol abuse
3.2
8.5
33
105
SPAT1104
SPAT
Monitoring of emergency patient
1.9
8.5
110
603
ZXA00
NOMESCO Finland
Right side
1.4
8.5
458
3513
H01
ICPC
Ear pain/earache
1.7
8.5
146
873
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
8.4
91
469
SPAT1240
SPAT
Therapeutic discussion
1.8
8.4
127
730
D99
ICPC
Disease digestive system other
3.9
8.4
24
62
K22.5
ICD-10 Finland
Diverticulum of oesophagus, acquired
90.5
8.4
9
*
K29.2
ICD-10 Finland
Alcoholic gastritis
90.5
8.4
9
*
R03BA08
ATC
ciclesonide; inhalant
1.8
8.4
126
723
P17
ICPC
Tobacco abuse
3.6
8.4
27
76
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.1
8.4
74
354
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
4.5
8.4
20
45
A06AC51
ATC
ispaghula, combinations; oral
2.2
8.3
70
328
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
2.9
8.3
38
133
UJG02
NOMESCO Finland
Proctoscopy
2.7
8.3
43
161
E66
ICD-10 Finland
Obesity
2.1
8.3
77
375
WX004
NOMESCO Finland
Patient-controlled sedation
8.6
8.3
17
20
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.3
8.3
62
277
L76
ICPC
Fracture: other
2.4
8.3
53
221
R4110, ,
SPAT
1.7
8.3
145
871
B03BA03
ATC
hydroxocobalamin; parenteral
2.0
8.3
85
431
D64.8
ICD-10 Finland
Other specified anaemias
3.0
8.3
36
123
M01AB55
ATC
diclofenac, combinations; oral
1.9
8.2
105
573
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.2
8.2
64
291
N03AX09
ATC
lamotrigine; oral
2.3
8.2
61
272
R07.2
ICD-10 Finland
Precordial pain
2.7
8.2
42
157
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.5
8.2
48
192
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.8
8.1
114
641
L05
ICPC
Flank/axilla symptom/complaint
1.9
8.1
107
590
T08
ICPC
Weight loss
3.1
8.1
32
103
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.8
8.1
112
627
SPAT1301
SPAT
No procedures
1.4
8.1
502
3936
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
3.0
8.1
35
119
J01FA10
ATC
azithromycin; systemic
1.3
8.1
865
7358
C09CA01
ATC
losartan; oral
1.4
8.1
467
3621
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
8.0
300
2149
EBA00
NOMESCO Finland
Extraction of tooth
1.4
8.0
586
4711
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.7
8.0
154
948
P06
ICPC
Sleep disturbance
1.6
8.0
180
1154
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.7
8.0
136
810
X58
ICD-10 Finland
Exposure to other specified factors
1.5
8.0
229
1553
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
8.0
281
1990
D07AA02
ATC
hydrocortisone; topical
1.6
8.0
193
1260
N02AA05
ATC
oxycodone; systemic
1.5
7.9
303
2180
R04.2
ICD-10 Finland
Haemoptysis
2.2
7.9
63
289
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.6
7.9
181
1166
R5140
NOMESCO Finland
Monitoring the use of the aid
1.6
7.9
207
1377
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.8
7.9
128
753
E000001, ,
ATC
1.5
7.8
286
2040
H25.8
ICD-10 Finland
Other senile cataract
1.6
7.8
186
1209
CS494
NOMESCO Finland
Other visual field testing
2.4
7.8
50
209
JN4BD
NOMESCO Finland
Extensive body CT
1.6
7.8
191
1251
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
7.8
1126
9968
SPAT1234
SPAT
Support of social functional capacity
2.0
7.8
81
413
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
7.8
112
636
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
7.7
222
1507
Z01.7
ICD-10 Finland
Laboratory examination
1.5
7.7
225
1532
U05
ICPC
Urination problems other
1.9
7.7
93
499
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
2.5
7.7
46
186
D20
ICPC
Mouth/tongue/lip symptom/complaint
2.1
7.7
68
326
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
7.7
100
550
M79.1
ICD-10 Finland
Myalgia
1.6
7.7
207
1386
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
4.5
7.7
18
40
45100
ICD-8 Finland
Phlebitis and thrombophlebitis, Of lower extremities
4.5
7.7
18
40
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
7.6
359
2683
TQW40
NOMESCO Finland
Remowal of suture of skin
1.8
7.6
118
684
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.8
7.6
106
595
R50.9
ICD-10 Finland
Fever, unspecified
1.5
7.6
233
1603
NB1AD
NOMESCO Finland
Shoulder CT examination
2.9
7.6
34
118
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
18.4
7.6
11
6
Z53.8
ICD-10 Finland
Procedure not carried out for other reasons
8.1
7.6
16
20
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
7.6
236
1630
R5110, ,
SPAT
1.8
7.5
111
634
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
4.1
7.5
20
49
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
6.2
7.5
19
31
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
2.6
7.5
42
164
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.6
7.5
197
1310
K03.28
ICD-10 Finland
Other erosion of teeth
2.8
7.5
36
130
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.9
7.5
34
119
R03AC12
ATC
salmeterol; inhalant
2.1
7.5
66
316
L12
ICPC
Hand/finger symptom/complaint
1.5
7.5
244
1701
WZC00, ,
SPAT
1.6
7.4
158
999
K86.1
ICD-10 Finland
Other chronic pancreatitis
4.4
7.4
18
41
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
7.4
460
3600
Z04.3
ICD-10 Finland
Examination and observation following other accident
2.7
7.4
39
148
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.6
7.4
151
945
K01
ICPC
Heart pain
3.4
7.4
26
78
FN1AD
NOMESCO Finland
CT of coronary arteries
2.9
7.4
34
120
Z3226
NOMESCO Finland
Physiotherapist
1.5
7.4
288
2080
N06AB03
ATC
fluoxetine; oral
1.6
7.4
179
1169
R52.2
ICD-10 Finland
Other chronic pain
2.2
7.4
57
259
D73
ICPC
Gastroenteritis presumed infection
2.9
7.3
33
115
JAH01
NOMESCO Finland
Laparoscopy
2.2
7.3
58
266
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
3.1
7.3
30
99
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
7.3
203
1367
C03DA01
ATC
spironolactone; oral
1.5
7.3
203
1367
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
3.6
7.3
23
64
SPAT1312
SPAT
General health counselling
1.4
7.3
485
3835
T90
ICPC
Diabetes non-insulin dependent
1.4
7.3
451
3526
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
7.3
103
581
5301X
ICD-9 Finland
Diseases of oesophagus, Oesophagitis[OESOPHAGITIS NUD]
+∞
7.3
7
*
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
2.9
7.3
32
110
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
7.3
709
5926
D12
ICPC
Constipation
2.2
7.3
60
280
WX720
NOMESCO Finland
Own respiration
1.9
7.3
87
466
A05
ICPC
Feeling ill
2.1
7.2
67
327
SPAT1227
SPAT
Substance abuse rehabilitation
6.3
7.2
18
29
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
6.3
7.2
18
29
R51
ICD-10 Finland
Headache
2.1
7.2
64
307
D90
ICPC
Hiatus hernia
15.8
7.2
11
7
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
7.2
169
1094
N05BE01
ATC
buspirone; oral
2.4
7.2
46
192
J01FA09
ATC
clarithromycin; systemic
1.4
7.2
458
3597
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
7.3
7.2
16
22
K59.0
ICD-10 Finland
Constipation
2.0
7.2
80
418
SPAT1058
SPAT
PEF monitoring instruction
1.7
7.2
132
804
L14
ICPC
Leg/thigh symptom/complaint
1.7
7.2
126
758
S22.3
ICD-10 Finland
Fracture of rib
1.7
7.2
133
812
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.9
7.1
94
519
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
2.9
7.1
33
117
Z98.8
ICD-10 Finland
Other specified postsurgical states
3.4
7.1
25
75
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
7.1
365
2769
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
2.0
7.1
73
371
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.1
7.1
64
310
J01DA01
ATC
[U] cefalexin
1.3
7.1
1001
8784
A10BA02
ATC
metformin; oral
1.3
7.1
520
4174
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.4
7.1
46
194
SFA30
NOMESCO Finland
Three-surface restoration
1.3
7.1
714
5993
WZC30
NOMESCO Finland
Teaching
1.4
7.0
284
2063
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
7.0
230
1604
WVA40
NOMESCO Finland
Initiation and monitoring of intravenous hydration
2.9
7.0
31
107
G04CB01
ATC
finasteride; oral
1.5
7.0
226
1571
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
2.2
7.0
54
245
K85
ICPC
Elevated blood pressure
1.4
7.0
278
2014
L04AX01
ATC
azathioprine; systemic
2.2
7.0
59
278
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
6.9
376
2876
M54
ICD-10 Finland
Dorsalgia
1.6
6.9
166
1081
N05AH03
ATC
olanzapine; systemic
1.9
6.9
89
488
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.7
6.9
138
859
ZXA05
NOMESCO Finland
Left side
1.4
6.9
417
3246
R00.2
ICD-10 Finland
Palpitations
1.8
6.9
101
577
PEN23
NOMESCO Finland
Plastic repair of femoral artery
3.6
6.9
22
62
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
6.9
478
3802
U71
ICPC
Cystitis/urinary infection other
1.9
6.9
87
475
B01AC04
ATC
clopidogrel; oral
1.4
6.9
306
2264
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
3.2
6.8
26
82
L16
ICPC
Ankle symptom/complaint
1.6
6.8
164
1068
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.1
6.8
64
314
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.4
6.8
451
3558
R06.4
ICD-10 Finland
Hyperventilation
3.3
6.8
25
77
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.8
6.8
95
534
G04BD12
ATC
mirabegron; oral
1.5
6.8
204
1396
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.8
6.8
106
616
S20.2
ICD-10 Finland
Contusion of thorax
1.8
6.8
91
505
R10.0
ICD-10 Finland
Acute abdomen
2.3
6.8
49
216
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.5
6.8
209
1438
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
11.0
6.8
12
11
L29
ICPC
Musculoskeletal sympt/complt other
1.7
6.8
132
816
M43.1
ICD-10 Finland
Spondylolisthesis
2.1
6.8
64
315
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.6
6.8
151
966
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.6
6.8
153
982
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
2.5
6.8
40
161
N05BA02
ATC
chlordiazepoxide; systemic
2.3
6.8
47
204
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.6
6.8
165
1079
JCA42
NOMESCO Finland
Other endoscopic procedure for hemostasis
40.2
6.8
8
*
JBB97
NOMESCO Finland
Laparoscopic repair of other diaphragmatic hernia
40.2
6.8
8
*
D14
ICPC
Haematemesis/vomiting blood
40.2
6.8
8
*
J01.4
ICD-10 Finland
Acute pansinusitis
4.3
6.8
17
40
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.3
6.7
51
230
NBG10
NOMESCO Finland
Acromioplastia
2.3
6.7
51
230
M48.0
ICD-10 Finland
Spinal stenosis
1.5
6.7
213
1477
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.0
6.7
65
324
N30.9
ICD-10 Finland
Cystitis, unspecified
1.9
6.6
75
394
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
6.6
212
1474
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
6.6
156
1014
D93
ICPC
Irritable bowel syndrome
4.2
6.5
17
41
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.7
6.5
113
677
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.9
6.5
85
468
R32
ICD-10 Finland
Unspecified urinary incontinence
2.4
6.5
41
170
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
2.9
6.5
30
106
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
6.5
437
3453
A02BDXX, ,
ATC
2.3
6.5
48
214
Z46.3
ICD-10 Finland
Fitting and adjustment of dental prosthetic device
2.7
6.5
33
123
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.5
6.5
247
1774
V03AA01, ,
ATC
2.7
6.5
34
129
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.6
6.5
35
135
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.8
6.5
92
521
M19.2
ICD-10 Finland
Other secondary arthrosis
3.1
6.5
26
85
SGA04
NOMESCO Finland
Opening and preparing the root canals, extremely complicated
1.6
6.4
160
1051
Y02
ICPC
Pain in testis/scrotum
3.9
6.4
18
46
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
3.9
6.4
18
46
S90.0
ICD-10 Finland
Contusion of ankle
2.8
6.4
30
107
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
6.4
233
1658
K26.7
ICD-10 Finland
Duodenal ulcer, chronic without haemorrhage or perforation
70.1
6.4
7
*
SPAT1360
SPAT
Extensive global examination
1.7
6.4
112
673
S42.1
ICD-10 Finland
Fracture of scapula
3.3
6.4
23
70
A02BX05
ATC
bismuth subcitrate; oral
3.0
6.4
27
91
N02BF02
ATC
pregabalin; oral
1.8
6.4
88
494
M01AH02
ATC
rofecoxib; oral
1.5
6.4
197
1358
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
1.5
6.4
204
1417
SPAT1059
SPAT
Spirometry at the office
1.8
6.3
89
502
L13
ICPC
Hip symptom/complaint
1.4
6.3
291
2163
ZXE00
NOMESCO Finland
One hour or less
1.3
6.3
603
5007
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
6.3
301
2253
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
6.3
116
708
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
3.3
6.3
23
71
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
1.9
6.3
79
431
55130
ICD-8 Finland
Other hernia of abdominal cavity without mention of obstruction, Diaphragmatic
18.1
6.3
9
5
K25.1
ICD-10 Finland
Gastric ulcer, Acute with perforation
+∞
6.3
6
*
JDA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in stomach or pylorus
26.8
6.2
8
*
TJX90
NOMESCO Finland
Other minor procedure in gastroenterological surgery
26.8
6.2
8
*
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
6.2
162
1077
SPAT1229
SPAT
Assessment of need for aid
1.6
6.2
128
805
N06AA12
ATC
doxepin; systemic
1.9
6.2
78
426
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.2
6.2
49
226
L86
ICPC
Back syndrome with radiating pain
1.8
6.1
91
522
Z71.8
ICD-10 Finland
Other specified counselling
1.3
6.1
446
3562
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.7
6.1
110
666
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
3.4
6.1
21
62
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.6
6.1
34
133
J46
ICD-10 Finland
Status asthmaticus
2.4
6.1
38
157
I95.9
ICD-10 Finland
Hypotension, unspecified
2.8
6.1
30
110
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
2.5
6.1
37
151
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
2.5
6.1
37
151
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
6.1
111
675
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.5
6.1
162
1081
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
1.7
6.1
96
561
G43.9
ICD-10 Finland
Migraine, unspecified
2.1
6.1
55
267
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
6.1
44
195
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
3.0
6.1
25
83
A99
ICPC
Disease/condition unspecnature/site
1.6
6.1
145
944
F29
ICPC
Eye symptom/complaint other
1.6
6.1
138
888
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
6.1
115
707
K57.1
ICD-10 Finland
Diverticular disease of small intestine without perforation or abscess
3.1
6.0
24
78
XQ802
NOMESCO Finland
Epicutan test
2.1
6.0
51
241
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
2.5
6.0
36
146
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.9
6.0
77
422
UJF02
NOMESCO Finland
Peroral enteroscopy
6.7
6.0
14
21
TKC20
NOMESCO Finland
Catheterisation of bladder
1.7
6.0
112
685
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
2.1
6.0
56
275

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1237
1394
23.54
307.65
2.1
1.2
—
—
—
0
0
808
3653
3.11
122.44
2.9
2.1
3.12
2.94
mg/l
1.06
713
3051
1058
5687
2.94
114.98
3.7
2.6
120.22
167.65
ug/l
7.50
978
5193
898
4596
2.81
104.21
3.3
2.4
56.33
60.56
u/l
1.59
835
4225
1305
8098
2.95
104.11
6.9
6.5
11.43
11.95
umol/l
0.60
1259
7723
1080
6442
2.57
86.81
2.4
1.9
97.25
94.32
pmol/l
1.07
602
3348
1120
6881
2.53
83.18
6.2
4.8
34.62
35.30
g/l
3.41
1059
6403
523
2227
2.86
83.08
2.6
2.4
2.38
2.26
g/l
4.15
494
2074
1635
12237
3.40
79.84
9.3
7.5
80.36
78.96
u/l
0.61
1562
11535
542
2400
2.76
79.43
2.7
2.4
11.15
13.22
umol/l
8.25
516
2250
877
4890
2.47
79.43
3.2
2.4
—
—
—
0
0
1136
7161
2.46
77.67
6.7
5.9
58.78
57.70
%
2.37
1066
6730
1129
7144
2.43
75.82
7.4
6.3
8.80
8.92
%
0.65
1064
6698
492
2118
2.78
75.71
2.7
2.5
19.00
23.43
%
8.61
411
1814
1143
7282
2.43
75.44
7.0
6.1
25.57
27.08
%
4.87
1078
6842
1124
7112
2.42
75.29
6.8
6.0
2.96
2.86
%
0.80
1061
6661
709
3666
2.49
74.71
1.7
1.5
19.95
20.51
nmol/l
0.42
592
3084
1098
6913
2.39
73.84
6.8
6.1
0.69
0.67
%
0.56
1035
6463
444
1836
2.85
73.54
2.3
2.5
1.72
1.74
%
0.15
372
1640
1202
7886
2.43
73.39
17.2
16.1
1.32
1.32
inr
0.00
307
2293
406
1614
2.93
72.23
1.4
1.3
—
—
—
0
0
1543
11446
2.85
71.20
5.1
3.8
13.47
12.49
mm/h
1.72
1417
10561
1356
9568
2.46
67.49
6.9
4.8
6.85
6.83
mmol/l
0.10
1302
9026
842
4888
2.30
66.25
3.7
3.2
32.62
39.50
u/l
1.17
800
4659
1185
7932
2.31
65.98
8.6
7.0
1.21
1.21
mmol/l
0.71
1036
6717
1109
7237
2.28
65.43
6.9
6.2
—
—
—
0
0
1150
7626
2.29
65.14
6.4
5.7
0.04
0.04
e9/l
1.11
1023
6511
1177
7898
2.29
64.53
7.0
5.9
0.20
0.20
e9/l
0.74
1052
6833
1143
7609
2.26
63.45
6.5
5.7
0.64
0.61
e9/l
3.18
1019
6496
1162
7788
2.27
63.43
6.5
5.8
1.86
1.93
e9/l
0.33
1046
6788
1443
10605
2.50
63.36
5.4
4.0
—
—
—
0
0
1114
7375
2.23
62.18
3.4
2.5
—
—
—
0
0
1362
9852
2.35
60.43
4.7
3.0
62.41
54.68
u/l
1.48
1263
9098
971
6133
2.19
60.37
2.6
2.1
—
—
—
0
0
1091
7238
2.19
59.56
7.6
6.3
1.20
1.21
mmol/l
0.68
986
6582
564
2864
2.38
59.47
2.0
1.7
1029.82
1181.00
nmol/l
3.70
431
2134
347
1413
2.78
58.01
2.1
2.6
67.25
67.97
e9/l
0.15
269
1059
679
3772
2.24
57.55
3.0
2.3
—
—
—
0
0
524
2624
2.38
56.64
1.3
1.2
2.06
1.79
u/ml
0.16
88
701
948
6139
2.09
52.85
4.6
3.5
38.17
58.26
ng/l
0.79
712
4559
369
1623
2.58
52.49
2.6
2.8
8.04
8.90
umol/l
0.27
336
1437
220
734
3.26
52.16
2.7
2.3
—
—
—
0
0
1247
8979
2.13
51.77
9.4
9.1
4.26
4.21
e9/l
0.34
1123
7754
1346
10032
2.17
50.31
5.6
4.2
137.41
911.14
e6/l
0.98
17
166
914
5966
2.02
48.49
2.6
2.1
75.95
77.82
nmol/l
1.10
796
5249
472
2426
2.26
46.82
1.4
1.5
2.84
2.62
g/l
0.96
253
1484
315
1362
2.57
45.99
2.4
2.2
152.62
168.56
ug/g
0.31
261
1089
334
1497
2.49
45.14
2.6
2.0
0.21
0.21
g/l
0.27
312
1403
421
2107
2.28
44.24
5.5
6.0
1.02
1.03
mmol/l
0.12
392
1963
761
4785
1.98
43.61
5.3
3.9
—
—
—
0
0
1806
15702
4.01
43.42
23.7
14.1
24.18
26.27
mg/l
1.89
1591
12378
779
4948
1.97
43.26
3.3
2.9
1523.01
1382.53
ng/l
0.38
662
4259
334
1535
2.43
42.56
4.4
4.3
—
—
—
0
0
672
4096
1.99
41.68
5.4
3.9
87.62
87.78
%
0.05
657
4013
201
757
2.85
38.19
1.6
1.8
1.61
1.54
g/l
0.45
178
643
1666
14084
2.48
38.13
5.2
4.3
1.98
2.07
mu/l
0.40
1494
12701
195
730
2.86
37.44
1.2
1.3
—
—
—
0
0
127
371
3.60
36.87
1.7
1.6
—
—
—
0
0
381
1958
2.18
36.85
5.2
4.6
32.08
32.22
%
0.08
262
1275
712
4584
1.88
36.37
5.1
4.3
—
—
—
0
0
234
986
2.57
35.57
3.9
3.7
5.16
5.13
kpa
0.27
217
940
231
973
2.56
35.13
3.9
3.7
7.42
7.41
ph
0.29
22
129
162
584
2.94
33.24
4.1
4.2
24.55
24.78
mmol/l
0.41
148
540
222
950
2.51
32.57
1.2
1.2
—
—
—
0
0
1845
16728
4.49
31.99
27.8
16.7
139.31
139.74
mmol/l
9.17
1808
16330
180
702
2.73
31.86
4.0
3.9
—
—
—
0
0
220
956
2.47
31.18
11.1
11.0
—
—
—
0
0
524
3192
1.89
30.82
5.3
3.6
450.67
755.08
ng/l
0.48
437
2646
1844
16780
4.30
30.35
28.0
16.9
4.00
3.99
mmol/l
0.03
1801
16363
541
3359
1.85
29.80
1.8
1.7
129148397.55
20760655.41
pmol/l
1.51
446
2736
281
1396
2.19
29.08
4.1
2.3
32.90
41.68
u/l
1.00
234
1212
729
4979
1.75
28.97
2.4
2.1
344.53
252.14
u/l
0.36
688
4680
1376
11227
1.82
28.86
4.0
3.6
14.94
14.93
pmol/l
0.05
1235
10076
328
1742
2.07
28.50
3.5
4.4
8.97
24.32
ug/l
1.49
267
1434
357
1957
2.01
28.42
9.4
8.0
0.68
1.10
mmol/l
1.12
303
1576
334
1794
2.05
28.11
1.4
1.3
740.95
493.71
titre
1.10
84
350
333
1791
2.04
27.91
9.7
8.2
95.64
95.70
%
0.07
322
1727
450
2697
1.88
27.39
3.4
3.3
0.80
0.82
mmol/l
3.54
421
2531
517
3239
1.82
27.27
1.8
1.7
1.23
1.29
mg/l
0.17
406
2528
657
4423
1.74
27.03
3.4
3.1
—
—
—
0
0
1806
16392
3.04
26.56
23.3
13.3
—
—
—
0
0
351
1963
1.97
26.21
9.6
7.9
5.04
5.13
kpa
0.96
339
1887
350
1963
1.96
25.89
9.6
7.9
11.94
12.13
kpa
0.27
339
1883
207
950
2.32
25.81
3.5
3.2
4.20
6.33
e9/l
1.77
143
752
116
403
3.00
25.36
1.3
1.3
—
16.66
—
0
9
1846
17037
3.89
24.95
14.7
10.4
26.65
27.40
u/l
0.85
1782
16377
505
3227
1.77
24.51
3.4
2.8
539.51
558.87
mosm/kgh2o
1.21
424
2781
387
2316
1.84
23.23
2.3
2.0
—
—
—
0
0
303
1676
1.96
23.14
10.2
8.6
119.15
123.15
g/l
2.99
296
1632
775
5641
1.63
22.71
4.1
3.8
12.68
8.04
mg/mmol
0.90
515
3658
1700
15216
2.11
22.35
7.6
5.9
40.63
40.36
mmol/mol
0.57
1551
13995
810
5989
1.61
22.07
3.7
3.1
5.71
5.76
ph
0.16
38
375
106
379
2.90
22.01
1.8
1.4
298.75
275.80
ug/g
0.54
65
226
1871
17580
5.07
21.31
35.4
20.8
6.89
6.74
e9/l
1.81
1835
17012
755
5528
1.61
21.18
3.4
3.2
7.32
7.93
mmol/l
3.42
612
4664
567
3867
1.66
21.17
6.9
6.9
—
—
—
0
0
978
7613
1.59
21.13
4.1
3.4
0.00
0.00
estimate
0.80
131
1374
1870
17575
4.93
21.05
35.4
20.9
250.45
241.52
e9/l
6.46
1836
17071
1870
17577
4.92
21.00
35.3
20.7
30.15
30.51
pg
12.55
1848
17302
1870
17578
4.91
20.98
35.4
20.8
90.87
91.46
fl
5.90
1848
17305
1869
17563
4.81
20.96
35.7
21.0
39.44
40.90
%
4.94
1716
16366
1870
17579
4.91
20.95
35.4
20.8
4.44
4.53
e12/l
10.67
1832
17015
1870
17584
4.89
20.84
35.7
21.0
132.33
137.39
g/l
33.78
1849
17312
1737
15754
2.19
20.77
5.9
4.7
6.14
6.06
mmol/l
1.75
1582
14245
966
7526
1.58
20.59
5.7
4.6
0.00
0.00
estimate
-0.00
139
1454
90
308
3.02
20.21
1.2
1.1
16.16
6.06
u/ml
—
5
32
962
7536
1.56
19.67
4.1
3.4
0.01
0.00
estimate
0.37
146
1528
304
1781
1.84
19.24
2.0
1.8
—
—
—
0
0
253
1397
1.94
19.23
2.5
2.8
65.28
66.33
g/l
1.19
229
1279
714
5247
1.58
19.22
3.2
3.6
2.34
2.35
mmol/l
2.10
598
4615
725
5362
1.57
18.89
3.6
3.2
1002.33
263.12
mg/l
1.97
474
3533
92
332
2.86
18.80
3.3
2.5
32.70
36.94
umol/l
0.62
82
300
231
1255
1.96
18.38
2.1
2.4
382.10
374.33
nmol/l
0.21
210
1156
151
703
2.25
18.08
7.6
5.3
0.91
0.88
%
0.34
143
659
483
3279
1.63
17.86
4.1
3.8
1.02
1.02
kg/l
1.03
112
456
404
2621
1.69
17.82
3.6
3.0
2.34
1.73
e6/l
0.57
250
1426
265
1522
1.86
17.79
6.8
7.3
10.64
10.11
mmol/l
0.51
253
1444
213
1146
1.97
17.40
2.2
2.6
—
—
—
0
0
404
2643
1.67
17.19
2.0
2.1
30.04
30.00
s
0.05
386
2567
128
569
2.34
17.08
2.8
3.9
39.74
54.54
mg/l
0.68
111
465
209
1125
1.96
17.04
1.5
1.4
—
—
—
0
0
128
570
2.34
17.01
2.8
3.9
55.60
54.15
mg/l
0.06
112
465
669
4955
1.54
16.83
4.3
3.2
41.26
98.22
e6/l
1.93
543
3837
149
712
2.19
16.73
7.8
5.2
1.74
1.64
%
0.72
140
668
246
1408
1.86
16.65
1.5
1.5
—
—
—
0
0
98
392
2.58
16.43
10.1
7.0
11.40
11.27
mmol/l
0.13
92
349
98
392
2.58
16.43
10.1
7.0
104.39
105.38
mmol/l
0.91
92
349
302
1846
1.76
16.41
1.5
1.4
—
—
—
0
0
607
4421
1.55
16.39
3.0
2.8
5080.70
5024.47
umol/l
0.01
522
3866
237
1347
1.87
16.38
1.5
1.6
—
—
—
0
0
244
1401
1.85
16.33
10.5
9.2
—
—
—
0
0
644
4756
1.54
16.30
4.4
4.2
7.41
7.40
ph
0.66
90
932
1765
16351
2.11
16.03
5.9
5.2
2.59
2.70
mmol/l
4.83
1597
14971
285
1732
1.76
15.77
1.6
1.5
—
—
—
0
0
120
540
2.30
15.57
9.6
6.3
1.23
1.33
mmol/l
0.70
109
481
1736
16024
1.96
15.38
5.2
4.6
4.43
4.57
mmol/l
6.43
1583
14744
199
1095
1.91
15.16
2.5
2.8
10.37
10.38
g/l
0.01
184
1000
247
1456
1.80
15.13
1.6
1.5
—
—
—
0
0
149
747
2.08
14.78
2.6
2.7
—
—
—
0
0
199
1113
1.88
14.41
3.9
4.1
100.62
95.84
ng/l
0.21
175
964
131
639
2.13
13.96
2.2
2.7
7.48
7.36
g/l
0.31
117
583
131
639
2.13
13.96
2.2
2.7
3.71
3.71
g/l
0.02
117
583
727
5645
1.47
13.85
5.1
3.6
122.90
98.59
e6/l
0.21
564
4091
356
2373
1.62
13.76
1.3
1.2
74.04
39.75
iu/ml
0.36
115
750
252
1537
1.74
13.67
4.6
3.6
1.52
1.99
mmol/l
1.07
213
1288
94
405
2.39
13.48
1.7
1.4
0.24
0.24
g/l
0.44
85
384
160
853
1.96
13.37
1.5
1.9
1.24
1.45
g/l
0.66
146
778
112
526
2.20
13.14
2.9
3.2
0.48
0.26
g/l
1.38
46
233
1715
15902
1.80
13.06
5.4
4.5
1.37
1.42
mmol/l
4.21
1554
14531
69
261
2.71
12.97
1.5
1.3
—
—
—
0
0
146
769
1.97
12.63
1.4
1.3
342.44
228.80
u/ml
0.47
131
708
122
602
2.10
12.63
2.3
2.8
2.89
2.96
g/l
0.26
108
546
50
162
3.14
12.41
1.4
1.3
—
—
—
0
0
67
256
2.68
12.36
1.7
1.4
—
—
—
0
0
247
1541
1.69
12.29
4.7
3.6
5.70
5.87
kpa
1.98
240
1489
400
2807
1.54
12.24
3.5
2.8
0.96
1.10
e6/l
0.31
243
1603
1665
15365
1.67
12.21
4.7
4.1
1.35
1.32
mmol/l
0.71
1512
13934
195
1140
1.79
12.21
6.9
4.8
—
—
—
0
0
93
418
2.29
12.14
2.8
4.2
—
—
—
0
0
468
3406
1.50
12.03
3.1
2.5
3.72
4.70
e6/l
1.26
417
3074
93
420
2.28
12.00
1.8
1.4
1.18
1.20
g/l
0.13
84
398
575
4369
1.45
11.84
4.1
3.1
—
—
—
0
0
64
245
2.67
11.78
1.4
1.3
59.16
59.33
mmol/l
0.01
51
199
56
203
2.81
11.44
1.7
1.5
0.79
0.87
g/l
0.21
42
155
119
605
2.03
11.38
2.3
2.7
10.52
10.25
g/l
0.25
101
546
232
1457
1.67
11.23
1.3
1.4
—
—
—
0
0
51
178
2.92
11.16
3.0
2.5
—
—
—
0
0
116
592
2.02
10.98
3.0
3.5
137.86
2396.73
u/ml
0.76
100
517
78
346
2.31
10.53
1.2
1.2
85.00
97.50
titre
0.21
12
28
29
74
3.96
10.31
13.6
15.9
—
—
—
0
0
583
4533
1.41
10.30
4.3
3.1
0.40
0.45
e6/l
0.17
464
3465
181
1095
1.72
10.04
8.8
6.9
24.54
24.58
mmol/l
0.05
172
1045
182
1103
1.72
10.03
10.9
10.0
94.39
94.02
%
0.59
182
1097
227
1469
1.62
9.73
3.5
2.7
175.93
196.36
ng/l
0.46
214
1350
82
385
2.18
9.68
2.5
3.4
310.79
1205.32
u/ml
0.70
76
356
28
75
3.77
9.34
1.4
1.2
134.04
140.07
nmol/l
0.19
28
75
958
8176
1.35
9.15
5.6
4.9
2.51
3.40
ug/l
0.67
848
7362
128
724
1.82
8.95
1.3
1.3
—
—
—
0
0
84
412
2.09
8.90
3.0
3.1
25.46
24.83
mmol/l
0.76
79
404
466
3569
1.40
8.75
3.5
3.3
—
—
—
0
0
75
355
2.16
8.71
1.4
1.2
17.57
6.91
u/ml
0.32
13
49
44
163
2.74
8.70
1.3
1.1
—
—
—
0
0
315
2249
1.48
8.63
1.3
1.2
10.89
12.23
u/ml
0.09
89
874
40
142
2.86
8.56
1.1
1.0
3.19
2.10
u/ml
0.44
14
58
29
85
3.45
8.51
3.6
2.6
—
—
—
0
0
539
4248
1.38
8.48
1.3
1.3
—
—
—
0
0
298
2117
1.48
8.35
1.5
1.3
—
—
—
0
0
117
660
1.82
8.26
2.1
1.7
—
—
—
0
0
508
4006
1.37
7.87
4.1
3.2
—
—
—
0
0
191
1249
1.59
7.82
3.7
2.9
4.61
4.54
kpa
0.15
185
1203
20
48
4.20
7.74
1.3
1.4
60.57
91.39
umol/l
—
7
28
72
352
2.09
7.73
1.4
1.2
3.30
2.59
u/ml
0.21
11
28
92
492
1.91
7.69
1.4
1.2
3.40
1.21
u/ml
—
5
45
121
706
1.76
7.65
2.6
2.0
2.00
2.61
ug/l
0.29
108
633
74
370
2.04
7.49
3.6
3.0
—
—
—
0
0
71
351
2.06
7.41
1.1
1.2
—
—
—
0
0
39
148
2.67
7.40
1.1
1.3
—
—
nmol/l
—
0
0
70
347
2.06
7.26
2.3
2.1
130.63
130.02
g/l
0.06
46
254
31
106
2.96
7.13
1.2
1.1
336.62
364.40
nmol/l
0.27
24
85
27
85
3.21
7.12
1.3
1.4
1.61
1.21
nmol/l
0.46
20
62
115
676
1.75
7.10
1.2
1.2
—
—
—
0
0
94
524
1.84
6.94
2.0
2.6
36.36
37.93
g/l
1.64
79
468
126
770
1.68
6.77
2.8
2.5
1.27
1.23
%
0.13
126
765
52
237
2.23
6.70
1.2
1.2
—
—
—
0
0
54
251
2.19
6.63
2.3
2.4
—
—
—
0
0
77
411
1.91
6.52
4.3
4.0
—
—
—
0
0
41
171
2.43
6.46
1.4
1.2
108.02
39.77
u/ml
—
6
7
18
46
3.94
6.44
1.2
1.8
—
—
—
0
0
45
197
2.32
6.38
1.1
1.1
1.53
1.53
g/l
0.02
40
180
32
119
2.72
6.35
1.5
1.3
0.52
0.38
g/l
0.40
24
81
32
119
2.72
6.35
1.5
1.3
7.48
7.26
g/l
0.11
23
80
32
119
2.72
6.35
1.5
1.3
3.15
2.98
g/l
0.26
23
81
25
81
3.11
6.32
1.1
1.1
—
—
—
0
0
32
120
2.70
6.26
1.5
1.3
—
—
—
0
0
1461
13589
1.32
6.12
29.7
17.1
16.26
14.98
%
9.61
1449
13317
35
141
2.51
5.96
1.3
1.2
274.97
276.94
mosm/kgh2o
0.17
29
102
46
211
2.21
5.87
2.1
2.2
467.35
261.10
u/ml
0.18
46
204
43
193
2.26
5.78
1.3
1.6
56.27
63.11
%
0.50
30
114
81
459
1.80
5.72
3.7
3.3
—
—
—
0
0
74
411
1.83
5.58
1.6
1.6
6527.57
14861.34
e6/l
2.12
54
286
222
1609
1.43
5.55
2.6
2.2
12.54
13.03
nmol/l
0.41
188
1431
23
77
3.01
5.53
1.1
1.0
—
—
—
0
0
53
264
2.04
5.50
1.4
1.2
33.56
53.26
u/ml
—
5
19
55
280
1.99
5.39
1.3
1.4
—
—
—
0
0
31
124
2.52
5.38
1.3
1.3
11.12
13.31
u/l
0.43
26
115
37
161
2.32
5.36
2.5
3.2
30.11
21.37
mg/l
0.25
25
127
135
894
1.55
5.28
1.4
1.4
—
—
—
0
0
534
4450
1.28
5.25
1.7
1.6
1.43
1.38
mmol/l
0.61
454
3685
20
64
3.15
5.19
3.6
2.8
42870.00
38637.58
ug/l
0.86
20
64
41
190
2.18
5.14
2.4
2.3
—
—
—
0
0
15
40
3.77
5.09
1.3
1.2
4.41
196.62
ug/l
—
7
19
37
168
2.23
4.89
3.2
2.7
—
—
—
0
0
36
162
2.25
4.86
1.4
1.2
—
—
—
0
0
77
454
1.73
4.80
1.1
1.1
—
—
—
0
0
142
972
1.50
4.78
3.6
2.9
—
—
—
0
0
38
177
2.17
4.73
1.1
1.3
0.20
0.31
nmol/l
—
5
16
215
1595
1.39
4.72
1.5
1.5
—
—
—
0
0
27
108
2.52
4.72
2.3
2.1
—
—
—
0
0
17
53
3.23
4.61
2.6
2.2
—
—
—
0
0
35
160
2.21
4.57
1.2
1.1
—
—
—
0
0
24
92
2.63
4.57
1.8
3.0
7.39
7.43
ph
—
5
36
188
1372
1.41
4.54
3.5
4.0
0.84
0.87
%
0.08
71
476
64
365
1.78
4.49
1.5
1.7
—
—
—
0
0
48
250
1.94
4.46
1.2
1.4
103.44
127.64
u/ml
0.47
12
37
38
183
2.10
4.37
2.1
2.5
1.17
1.57
g/24h
0.38
17
90
55
302
1.85
4.37
3.5
2.8
—
—
—
0
0
35
164
2.16
4.32
1.0
1.3
—
—
—
0
0
476
5607
0.80
4.29
3.3
3.0
—
—
—
0
0
796
7073
1.22
4.16
11.7
9.7
0.00
0.00
e9/l
0.97
667
5803
23
92
2.52
4.05
2.1
1.7
6.89
7.16
mmol/l
0.14
15
59
69
416
1.68
4.02
1.5
2.1
11.03
11.92
mg/l
0.35
60
387
33
156
2.14
4.01
3.6
3.2
—
—
—
0
0
60
349
1.74
3.98
1.9
1.4
0.84
0.84
nmol/l
0.01
50
289
1268
11822
1.22
3.93
4.7
3.9
—
—
—
0
0
31
145
2.16
3.87
2.8
1.9
—
—
—
0
0
53
300
1.79
3.86
1.4
1.6
—
—
—
0
0
43
230
1.89
3.75
1.5
1.5
29.44
33.30
g/l
1.21
37
209
13
34
3.84
3.69
1.4
1.1
247.00
265.10
pmol/l
—
8
21
59
350
1.71
3.67
3.7
3.6
—
—
—
0
0
24
103
2.35
3.67
2.0
1.7
—
—
—
0
0
109
750
1.48
3.64
3.3
3.5
4.62
4.44
pmol/l
1.22
96
658
115
801
1.46
3.62
4.3
3.1
—
—
—
0
0
46
255
1.82
3.60
1.1
1.2
358.65
282.80
u/ml
0.67
26
151
44
241
1.85
3.58
2.0
1.8
—
—
—
0
0
32
157
2.06
3.56
1.8
1.3
238838.81
94175.67
e6/l
0.27
16
105
33
164
2.03
3.55
1.6
2.0
—
1360.00
—
0
6
8
13
6.17
3.50
1.8
1.2
—
—
mmol/l
—
0
0
57
340
1.70
3.49
1.6
1.4
7.83
8.61
u/l
0.24
45
276
135
978
1.41
3.45
2.7
2.4
21.74
21.36
au/ml
—
7
70
42
230
1.84
3.43
2.4
2.4
—
—
—
0
0
15
53
2.84
3.36
1.7
2.8
—
—
—
0
0
28
134
2.11
3.34
1.1
1.1
—
—
—
0
0
35
183
1.93
3.30
1.1
1.5
—
—
—
0
0
12
33
3.65
3.29
1.5
2.6
—
—
—
0
0
47
271
1.75
3.26
1.2
1.2
—
—
—
0
0
34
177
1.94
3.25
1.6
1.5
—
—
—
0
0
172
1312
1.34
3.22
3.6
4.1
0.10
0.12
%
0.19
55
417
44
250
1.78
3.21
1.3
2.3
—
—
—
0
0
13
44
2.97
3.13
1.5
1.5
—
—
—
0
0
17
67
2.55
3.13
1.1
5.2
96.08
57.61
mg/l
1.00
12
56
10
25
4.02
3.08
1.1
1.5
—
—
—
0
0
15
56
2.69
3.06
38.9
33.1
7.67
7.31
ug/l
0.29
15
51
21
93
2.27
3.03
1.0
1.1
—
—
—
0
0
46
270
1.72
3.03
2.1
2.0
4.81
4.94
mmol/24h
0.08
40
236
50
302
1.67
2.97
2.0
1.8
6.36
4.87
iu/l
0.23
20
92
45
264
1.72
2.97
2.0
1.7
—
—
—
0
0
15
57
2.64
2.96
1.8
1.7
—
—
—
0
0
37
205
1.82
2.95
1.5
1.4
3200.59
2000.09
e6/l
0.34
27
145
30
155
1.95
2.95
2.4
1.9
11.63
11.24
%
0.17
30
155
62
397
1.58
2.93
1.0
1.1
—
—
—
0
0
8
17
4.72
2.92
1.1
1.3
—
—
—
0
0
33
177
1.88
2.91
1.5
1.4
—
—
—
0
0
49
297
1.67
2.88
1.4
1.4
29.12
29.08
iu/l
0.00
40
252
17
70
2.44
2.88
1.2
1.2
—
70.22
%
—
0
9
163
1258
1.32
2.84
3.3
3.8
0.61
0.67
%
0.19
62
405
24
116
2.08
2.83
1.6
1.2
—
—
—
0
0
41
238
1.74
2.82
1.2
1.2
133.34
190.28
miu/ml
—
10
95
13
47
2.78
2.81
1.9
2.2
—
—
—
0
0
44
261
1.70
2.81
2.0
1.7
—
—
—
0
0
189
1493
1.30
2.78
1.9
2.3
7.02
8.15
ug/l
0.41
156
1334
21
97
2.18
2.77
1.2
1.3
0.05
0.85
u/ml
1.31
13
56
43
255
1.70
2.75
2.7
3.2
—
—
—
0
0
160
1240
1.32
2.72
3.6
4.1
0.91
0.11
%
0.47
47
338
60
389
1.56
2.71
1.2
1.1
—
—
—
0
0
476
4169
1.19
2.68
4.4
3.7
0.02
0.00
estimate
0.37
132
1362
33
183
1.82
2.66
1.5
1.4
62403.86
131584.95
e6/l
0.55
22
115
43
260
1.67
2.58
2.1
1.6
—
—
—
0
0
349
2986
1.21
2.54
2.9
3.2
2.45
2.46
mmol/l
0.04
298
2659
62
412
1.52
2.53
2.9
3.1
1.78
1.58
mg/l
0.94
52
372
22
108
2.05
2.52
1.9
1.5
—
—
—
0
0
43
264
1.64
2.45
2.1
1.7
—
—
—
0
0
9
27
3.34
2.39
2.1
1.9
—
—
—
0
0
14
58
2.42
2.37
1.0
1.4
179.07
169.10
mmol/24h
0.18
14
58
45
283
1.60
2.35
1.7
1.4
—
—
—
0
0
20
98
2.05
2.31
3.8
3.8
—
—
—
0
0
31
177
1.76
2.30
1.3
1.4
5.77
6.50
mmol/l
1.34
26
165
32
186
1.73
2.25
2.9
3.8
—
—
—
0
0
52
344
1.53
2.21
3.0
3.1
0.72
0.83
nmol/l
1.04
41
265
9
30
3.01
2.14
1.8
1.2
—
—
—
0
0
10
36
2.79
2.13
1.3
1.4
—
—
—
0
0
10
36
2.79
2.13
1.1
1.0
—
—
—
0
0
22
116
1.91
2.11
1.3
1.2
102.50
68.75
titre
—
8
24
1370
13136
1.15
2.09
31.6
18.6
331.04
333.15
g/l
13.26
1364
13040
47
308
1.54
2.09
1.2
1.4
—
—
—
0
0
33
198
1.68
2.09
2.2
1.7
—
—
—
0
0
53
357
1.50
2.08
1.2
1.1
—
—
—
0
0
32
191
1.69
2.07
2.1
2.4
—
—
—
0
0
7
20
3.51
2.05
2.0
1.6
—
—
—
0
0
9
32
2.82
2.00
5.0
7.7
—
—
—
0
0
9
33
2.74
1.93
1.1
1.2
—
—
—
0
0
9
34
2.65
1.86
1.6
1.5
—
—
—
0
0
31
491
0.63
1.86
1.2
1.7
—
—
—
0
0
5
12
4.17
1.82
2.4
3.0
0.40
0.33
u/field
—
5
12
19
102
1.87
1.76
1.1
1.1
—
—
—
0
0
8
30
2.67
1.72
1.9
1.3
—
—
—
0
0
12
55
2.19
1.67
1.9
2.7
369.83
772.39
e6/l
—
6
44
10
40
2.51
1.66
4.7
7.9
—
—
—
0
0
10
40
2.51
1.66
1.1
1.1
—
—
—
0
0
10
41
2.45
1.64
1.7
2.3
—
—
—
0
0
92
1168
0.78
1.59
1.3
1.4
—
—
—
0
0
10
43
2.33
1.58
1.1
1.2
—
9.60
%
—
0
5
57
774
0.73
1.58
1.4
1.5
—
—
—
0
0
28
176
1.60
1.55
1.4
1.4
—
—
—
0
0
13
64
2.04
1.54
3.2
3.1
—
—
—
0
0
43
298
1.45
1.54
1.9
1.2
48.29
43.04
u/l
0.10
32
254
53
382
1.40
1.54
2.9
2.2
—
—
—
0
0
25
153
1.64
1.53
1.1
1.5
—
—
—
0
0
0
42
0.00
1.52
0.0
1.4
—
—
—
0
0
25
154
1.63
1.50
1.1
1.0
0.37
5.14
u/ml
—
10
68
50
360
1.40
1.47
1.2
1.2
3.72
3.86
mmol/l
0.71
45
334
32
211
1.53
1.46
1.1
1.1
—
—
—
0
0
54
396
1.37
1.43
1.2
1.3
579.14
553.47
mg/l
0.13
49
369
50
363
1.39
1.41
3.2
2.4
16.47
16.15
%
0.20
33
174
19
111
1.72
1.39
1.2
1.4
27.46
34.50
u/l
0.42
12
84
27
175
1.55
1.34
1.1
1.1
0.30
2.03
u/ml
2.11
14
92
10
47
2.13
1.33
1.1
1.3
—
—
—
0
0
36
249
1.45
1.33
1.1
1.1
301.00
94.85
iu/ml
—
6
51
0
41
0.00
1.31
0.0
1.3
—
—
—
0
0
0
41
0.00
1.31
0.0
1.3
—
—
—
0
0
23
145
1.59
1.29
2.6
2.1
650.41
603.21
ml
0.21
17
89
5
18
2.78
1.28
3.2
1.4
—
—
—
0
0
74
581
1.28
1.27
1.3
1.5
—
—
—
0
0
25
162
1.55
1.26
1.5
1.2
—
—
—
0
0
31
211
1.48
1.25
1.0
1.1
—
—
—
0
0
16
92
1.75
1.25
3.0
2.5
—
—
—
0
0
92
746
1.25
1.22
1.2
1.2
191.42
141.32
iu/ml
0.24
26
265
19
118
1.62
1.15
1.3
2.0
2.00
1.70
u/field
—
10
47
12
66
1.82
1.09
1.2
1.2
—
—
—
0
0
16
98
1.64
1.03
1.4
1.1
—
—
—
0
0
29
204
1.43
1.03
1.1
1.3
—
—
—
0
0
26
179
1.46
1.03
1.1
1.1
—
—
—
0
0
20
130
1.54
1.02
1.1
1.2
—
—
—
0
0
512
4791
1.09
0.98
3.4
3.0
0.73
0.76
ug/l
0.13
353
3186
73
594
1.24
0.98
1.6
2.1
23.06
21.84
s
0.29
64
535
20
132
1.52
0.97
2.2
2.3
—
—
—
0
0
7
36
1.95
0.97
1.0
1.6
94.57
268.44
nmol/24h
—
7
36
22
149
1.48
0.95
1.0
1.1
0.20
1.18
u/ml
—
8
55
9
51
1.77
0.94
1.1
1.2
—
—
—
0
0
6
28
2.15
0.91
1.0
1.0
—
—
—
0
0
6
29
2.07
0.89
1.0
2.0
—
—
—
0
0
57
457
1.25
0.89
2.7
2.2
198.61
82.64
ug/min
0.70
33
278
12
71
1.69
0.89
1.2
1.0
—
—
—
0
0
8
45
1.78
0.84
2.5
5.3
—
—
—
0
0
53
426
1.25
0.82
4.8
4.2
7.44
7.42
ph
1.63
46
390
11
65
1.70
0.82
1.1
1.1
—
—
—
0
0
9
53
1.70
0.75
1.0
1.1
—
14.20
—
0
5
24
175
1.38
0.74
1.0
1.1
—
—
—
0
0
24
175
1.38
0.74
1.0
1.1
—
—
—
0
0
16
109
1.47
0.71
1.1
1.4
—
—
—
0
0
7
41
1.71
0.70
1.6
1.4
—
—
—
0
0
9
59
1.53
0.68
1.3
1.1
—
—
—
0
0
19
136
1.40
0.66
1.2
1.1
—
—
—
0
0
17
120
1.42
0.64
2.3
1.8
117.00
489.60
u/l
—
6
36
22
164
1.35
0.62
1.9
1.4
37.83
26.50
%
0.76
12
101
38
308
1.24
0.59
1.1
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
6
36
1.67
0.56
2.7
3.1
3.81
6.35
mg/l
—
6
31
5
89
0.56
0.56
2.8
2.7
7.60
10.04
mmol/l
—
5
89
25
194
1.29
0.56
1.2
1.4
39.21
53.15
mu/l
0.26
25
171
5
90
0.55
0.55
6.2
6.8
—
—
—
0
0
44
367
1.20
0.54
4.7
4.5
2.23
2.56
mmol/l
0.44
29
248
9
61
1.48
0.53
1.3
2.4
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
—
—
—
0
0
13
91
1.43
0.53
1.2
1.3
—
—
—
0
0
28
223
1.26
0.52
1.3
1.1
6.18
4.38
u/ml
0.30
17
90
18
135
1.34
0.51
1.1
1.1
1.10
1.69
u/ml
—
9
63
146
1336
1.10
0.51
2.8
3.2
—
—
—
0
0
16
118
1.36
0.50
1.1
1.1
0.87
2.69
u/ml
—
9
51
7
45
1.56
0.49
1.3
1.3
—
—
—
0
0
14
102
1.38
0.47
1.1
1.0
—
—
—
0
0
7
48
1.46
0.46
1.0
1.0
1593.57
1343.85
miu/ml
—
7
48
24
193
1.25
0.43
1.2
1.2
7.10
7.46
mmol/l
0.23
19
165
14
104
1.35
0.43
1.3
1.3
—
—
—
0
0
21
167
1.26
0.41
1.5
1.2
—
—
—
0
0
42
361
1.17
0.40
2.9
3.4
18.36
28.50
mg/l
1.94
25
226
5
34
1.47
0.40
1.2
3.4
—
—
—
0
0
0
19
0.00
0.39
0.0
8.2
—
0.34
—
0
19
33
281
1.18
0.36
3.0
3.2
4.08
4.33
e9/l
0.33
33
281
23
189
1.22
0.36
1.3
1.1
—
12.17
—
0
12
11
146
0.75
0.36
2.5
2.5
13.35
13.20
%
0.19
11
146
34
292
1.17
0.34
3.0
3.4
59.35
58.12
%
0.25
34
292
10
73
1.37
0.34
1.9
1.5
—
—
—
0
0
14
109
1.29
0.33
1.1
1.1
1.69
2.66
u/ml
—
5
39
68
616
1.11
0.33
1.1
1.1
—
—
—
0
0
122
1308
0.93
0.32
5.0
3.7
—
—
—
0
0
7
56
1.25
0.29
1.3
1.1
—
—
—
0
0
39
346
1.13
0.27
1.2
1.5
226.38
969.51
e6/l
1.08
32
275
39
346
1.13
0.27
1.2
1.4
2.59
32.83
e6/l
1.04
29
263
9
75
1.20
0.25
1.1
2.7
1039.67
1323.33
u/ml
—
9
75
48
528
0.91
0.24
1.3
1.2
—
—
—
0
0
6
84
0.71
0.24
1.2
1.3
1.66
1.52
g/l
—
6
84
56
514
1.09
0.23
1.6
1.7
—
—
—
0
0
91
853
1.07
0.23
1.3
1.3
—
—
—
0
0
59
544
1.09
0.22
12.4
10.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
6
49
1.23
0.20
2.0
1.2
—
—
—
0
0
19
218
0.87
0.19
3.0
3.9
14.47
30.42
u/ml
2.22
19
213
19
165
1.15
0.19
1.3
1.2
—
—
—
0
0
7
62
1.13
0.17
1.3
1.2
—
—
—
0
0
13
110
1.18
0.17
1.8
1.4
75.77
89.61
umol/l
2.08
13
110
31
282
1.10
0.16
1.1
1.3
—
—
—
0
0
9
79
1.14
0.15
1.3
1.8
—
—
—
0
0
9
106
0.85
0.13
2.7
1.3
—
—
—
0
0
133
1361
0.98
0.08
4.2
3.9
1.22
1.22
mmol/l
1.03
125
1186
67
689
0.97
0.06
4.6
4.3
—
—
—
0
0
10
90
1.11
0.05
2.4
2.7
—
—
—
0
0
15
157
0.96
0.01
1.7
1.5
131.47
224.67
pmol/l
0.84
15
157
12
116
1.03
0.00
1.4
3.9
15.22
53.77
u/ml
2.03
12
116
15
154
0.97
0.00
1.3
1.6
—
—
—
0
0
10
98
1.02
0.00
1.3
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
8
84
0.95
-0.00
1.9
2.8
1875.00
2008.79
ml
—
8
71
9
95
0.95
-0.00
2.3
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
90.88
—
0
8

Mortality – FinRegistry

Association

Association between endpoint K11_BARRET and mortality.

Females

Parameter HR [95% CI] p-value
K11_BARRET 1.414 [1.09, 1.83] 0.008
Birth year 0.992 [0.98, 1.0] 0.077

During the follow-up period (1.1.1998 — 31.12.2019), 217 out of 2231 females with K11_BARRET died.

Males

Parameter HR [95% CI] p-value
K11_BARRET 1.55 [1.25, 1.92] < 0.001
Birth year 0.99 [0.98, 1.0] 0.039

During the follow-up period (1.1.1998 — 31.12.2019), 580 out of 4061 males with K11_BARRET died.

Mortality risk

Mortality risk for people of age

years, who have K11_BARRET.

N-year risk Females Males
1 0.123% 0.313%
5 0.75% 1.877%
10 1.949% 5.046%
15 3.682% 9.446%
20 6.433% 16.279%

Relationships between endpoints

Index endpoint: K11_BARRET – Barrett oesophagus

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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