Pleural plaque

J10_PLEURPLAGUE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J92
  • Cause of death: ICD-10 J92

2 out of 7 registries used, show all original rules.

3930

4. Check minimum number of events

None

3930

5. Include endpoints

None

3930

6. Filter based on genotype QC (FinnGen only)

3860

Control definitions (FinnGen only)

Control exclude
J10_PLEURA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J90-J94
Name in latin
Lamellae pleurae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 22511 3209 19103
Only index persons 19742 2946 16796
Unadjusted period prevalence (%)
Whole population 0.47 0.09 0.53
Only index persons 0.56 0.11 0.64
Median age at first event (years)
Whole population 70.41 72.57 70.00
Only index persons 69.71 72.31 69.25

-FinnGen-

Key figures

All Female Male
Number of individuals 3860 419 3441
Unadjusted period prevalence (%) 1.42 0.15 1.58
Median age at first event (years) 70.10 70.07 70.11

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3930
Matched controls
39300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
4.3
307.7
1195
3658
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.3
307.7
882
2026
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
4954.8
307.7
2853
21
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
11.8
307.7
439
414
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.5
307.7
1332
2867
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
11.9
307.7
854
898
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
309.5
307.7
440
16
J94.8
ICD-10 Finland
Other specified pleural conditions
170.4
307.7
225
14
J92.9
ICD-10 Finland
Pleural plaque without asbestos
3887.5
307.7
1375
5
Z57.2
ICD-10 Finland
Occupational exposure to dust
128.0
307.7
263
22
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
100.0
307.7
566
66
R03BB04
ATC
tiotropium bromide; inhalant
4.2
306.3
1036
3106
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
6.2
294.6
557
1027
R03AC02
ATC
salbutamol; inhalant
3.3
289.3
2403
12628
XG410
NOMESCO Finland
Flow-volume spirometry
7.0
272.5
445
706
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.8
265.3
531
1030
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
8.4
240.2
325
416
XX1AW
NOMESCO Finland
Written report from X-ray examination without contrast peformed elsewhere
33.0
217.8
140
44
R06.0
ICD-10 Finland
Dyspnoea
2.9
215.6
1573
7365
GD1AD
NOMESCO Finland
Thorax CT examination
4.9
213.3
512
1158
J96.1
ICD-10 Finland
Chronic respiratory failure
1029.9
201.9
196
*
TGC00
NOMESCO Finland
Bronchial lavation
7.3
196.9
302
445
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
7.3
185.6
283
414
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.2
165.4
488
1289
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
159.6
2444
15682
TGA30
NOMESCO Finland
Thoracocentesis
40.5
149.9
91
23
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.7
145.8
1024
4553
J45.9
ICD-10 Finland
Asthma, unspecified
2.8
139.6
903
3841
H02AB06
ATC
prednisolone; systemic
2.3
137.4
2162
13688
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
5.5
126.5
254
487
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.7
122.6
766
3182
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.6
121.3
440
1332
Z57.3
ICD-10 Finland
Occupational exposure to other air contaminants
41.3
120.8
73
18
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.5
119.8
310
736
J45.1
ICD-10 Finland
Nonallergic asthma
3.6
113.5
407
1221
XX1XW
NOMESCO Finland
Extensive written report from radiologist
6.2
112.9
197
330
R05
ICD-10 Finland
Cough
2.4
109.7
946
4561
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
5.8
101.8
191
343
J92
ICD-10 Finland
Pleural plaque
+∞
99.4
95
*
R03BA08
ATC
ciclesonide; inhalant
3.5
98.8
369
1134
J98.1
ICD-10 Finland
Pulmonary collapse
194.6
91.7
95
5
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.4
84.6
219
518
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.9
83.9
442
1659
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
6.4
81.3
136
218
R02
ICPC
Shortness of breath/dyspnoea
2.4
79.3
659
3083
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.0
78.2
234
617
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
78.1
1505
9637
C45.0
ICD-10 Finland
Mesothelioma of pleura
26.1
77.8
54
21
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
8.5
77.6
101
122
R03AK08
ATC
formoterol and beclometasone; inhalant
4.3
77.4
204
489
R95
ICPC
Chron obstructive pulmonary disease
3.8
75.3
244
680
J94.9
ICD-10 Finland
Pleural condition, unspecified
379.5
75.0
75
*
R03AK07
ATC
formoterol and budesonide; inhalant
2.3
74.5
702
3456
5110B
ICD-9 Finland
Pleurisy, Without mention of effusion or current tuberculosis[PLEURA-ADHEESIOT]
+∞
72.1
69
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
5.0
69.7
154
320
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
4.5
68.4
171
393
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
8.6
67.9
87
103
R03BA05
ATC
fluticasone; inhalant
2.2
67.7
663
3306
GAC00
NOMESCO Finland
Biopsy of pleura
94.3
67.1
74
8
R04.2
ICD-10 Finland
Haemoptysis
3.2
65.8
280
928
J96.0
ICD-10 Finland
Acute respiratory failure
82.7
65.2
73
9
R03BA01
ATC
beclometasone; inhalant
2.2
60.9
576
2823
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
7.2
57.6
86
122
J01AA02
ATC
doxycycline; systemic
1.8
56.7
2869
23566
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
6.0
56.3
100
170
A02BC02
ATC
pantoprazole; systemic
1.7
51.9
2583
20823
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
50.7
744
4260
R03BA02
ATC
budesonide; inhalant
2.0
50.6
616
3308
SPAT1263
SPAT
Sampling
1.7
48.8
1626
11759
J47
ICD-10 Finland
Bronchiectasis
4.1
47.2
131
326
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.4
47.2
175
532
R06.2
ICD-10 Finland
Wheezing
3.1
46.1
195
642
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
5.8
46.1
85
150
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
4.2
45.6
124
304
J01CA04
ATC
amoxicillin; systemic
1.7
44.8
2779
23227
XG474
NOMESCO Finland
Exhalation nntrogen oxide
4.4
44.0
110
253
R05
ICPC
Cough
1.8
43.5
824
5084
R03AC13
ATC
formoterol; inhalant
2.7
42.1
232
884
J43.2
ICD-10 Finland
Centrilobular emphysema
9.4
41.8
50
54
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.3
41.7
338
1543
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
39.1
852
5449
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
39.0
1645
12384
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
38.5
899
5858
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
4.1
38.4
106
263
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
2.8
38.2
203
759
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
+∞
37.6
36
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.6
37.1
89
198
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
70.6
37.0
42
6
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
3.2
36.3
151
492
J43.9
ICD-10 Finland
Emphysema, unspecified
3.6
36.0
122
350
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
35.7
1686
12936
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.0
35.5
164
568
C03CA01
ATC
furosemide; systemic
1.5
35.5
1681
12899
R03AC18
ATC
indacaterol; inhalant
5.4
35.4
70
132
J01MA14
ATC
moxifloxacin; systemic
2.0
34.9
384
1975
N02BE01
ATC
paracetamol; systemic, rectal
1.7
34.6
3266
29117
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
34.2
1118
7881
SPAT1310
SPAT
Counselling related to known health issue
1.6
33.5
1185
8502
5119X
ICD-9 Finland
Pleurisy, Unspecified pleural effusion
+∞
33.4
32
*
SPAT1058
SPAT
PEF monitoring instruction
2.1
33.4
328
1616
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
4.0
33.3
96
246
R03BB01
ATC
ipratropium bromide; inhalant
2.4
32.4
242
1065
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
7.8
31.9
44
57
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.3
31.3
239
1061
SPAT1312
SPAT
General health counselling
1.6
31.2
1121
8043
R94.2
ICD-10 Finland
Abnormal results of pulmonary function studies
6.5
30.7
50
78
R96
ICPC
Asthma
2.1
30.4
325
1651
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
5.3
29.6
59
112
TGD00
NOMESCO Finland
Needle biopsy of lung
6.9
29.3
45
66
XX1VW
NOMESCO Finland
Written report from radiologist
5.8
28.8
52
90
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
28.6
477
2805
R03AC03
ATC
terbutaline; inhalant
1.9
28.2
420
2386
XG466
NOMESCO Finland
Sleep oxymetry
2.9
28.1
136
484
R03AK11
ATC
formoterol and fluticasone; inhalant
3.5
27.7
95
275
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
27.6
940
6636
R01AD09
ATC
mometasone; nasal
1.5
27.1
1174
8717
J98.0
ICD-10 Finland
Diseases of bronchus, not elsewhere classified
62.5
27.0
31
5
M03BX02
ATC
tizanidine; oral
1.4
26.7
1688
13473
SPAT1325
SPAT
Vaccination
1.5
26.3
1500
11734
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
25.4
1469
11497
SPAT1301
SPAT
No procedures
1.5
25.3
1269
9666
GA3AT
NOMESCO Finland
Pleural cytology with ultrasound guidance
9.4
25.3
30
32
G47.3
ICD-10 Finland
Sleep apnoea
1.6
25.1
800
5547
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
25.0
469
2850
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.2
24.8
209
968
M54.5
ICD-10 Finland
Low back pain
1.5
24.7
1006
7351
J93.9
ICD-10 Finland
Pneumothorax, unspecified
130.8
24.6
26
*
J01MA12
ATC
levofloxacin; systemic
1.5
24.6
829
5819
A02BC05
ATC
esomeprazole; systemic
1.4
24.5
1334
10309
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
5.7
24.3
45
80
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
5.7
24.3
45
80
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
24.2
1157
8719
J01FA06
ATC
roxithromycin; oral
1.4
24.1
1254
9602
R03DC03
ATC
montelukast; oral
1.8
24.0
399
2339
C07AB07
ATC
bisoprolol; oral
1.4
23.9
2200
18631
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
3.9
23.5
70
184
R03BB07
ATC
umeclidinium bromide; inhalant
4.7
23.3
54
117
SPAT1153
SPAT
Removal of sutures
1.4
23.3
1293
10003
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
23.1
790
5551
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
22.9
1076
8067
J42
ICD-10 Finland
Unspecified chronic bronchitis
3.7
22.7
72
198
J45
ICD-10 Finland
Asthma
1.9
22.4
277
1478
R03DA04
ATC
theophylline; systemic, rectal
1.9
22.3
274
1460
J43.8
ICD-10 Finland
Other emphysema
7.1
22.0
33
47
J01DB01
ATC
cefalexin; oral
1.4
21.7
2848
25425
GX1K5
NOMESCO Finland
Diffusion capacity
6.5
21.7
35
54
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
6.5
21.7
35
54
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
21.5
413
2520
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.4
21.2
1411
11225
J96.9
ICD-10 Finland
Respiratory failure, unspecified
34.0
21.1
27
8
R99
ICPC
Respiratory disease other
3.1
20.9
89
295
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
20.8
1166
8996
SPAT1097
SPAT
Recording of ECG
1.5
20.8
636
4354
A02BC03
ATC
lansoprazole; oral
1.4
20.5
1038
7860
XG405
NOMESCO Finland
Education on PEF monitoring
3.6
20.4
66
184
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
20.3
954
7123
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
20.2
1324
10488
J46
ICD-10 Finland
Status asthmaticus
2.9
20.1
93
323
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
20.1
943
7035
N02AX02
ATC
tramadol; systemic, rectal
1.4
19.9
1587
12969
I50.0
ICD-10 Finland
Congestive heart failure
1.6
19.9
448
2849
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.1
19.9
199
986
J45.8
ICD-10 Finland
Mixed asthma
2.6
19.7
111
428
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
19.7
1395
11179
R03AC19
ATC
olodaterol
5.9
19.6
35
60
J98.6
ICD-10 Finland
Disorders of diaphragm
201.0
19.6
20
*
R03AL04
ATC
indacaterol and glycopyrronium bromide; inhalant
5.0
19.5
41
82
R28
ICPC
Limited function/disability (R)
3.5
19.5
66
190
C01DA14
ATC
isosorbide mononitrate; oral
1.4
19.1
987
7486
J20
ICD-10 Finland
Acute bronchitis
1.8
19.1
303
1751
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
19.0
928
6967
R03AL11
ATC
formoterol, glycopyrronium bromide and budesonide; inhalant
4.9
19.0
41
84
Y96.0
ICD-10 Finland
Work-related condition
7.3
18.6
27
37
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
2.8
18.3
89
318
A98
ICPC
Health maint/preventive medicine
1.5
18.2
3282
30388
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
18.2
133
580
SPAT1260
SPAT
Consultation of another employee
1.5
18.2
649
4580
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
18.2
460
3009
R03AC12
ATC
salmeterol; inhalant
2.0
18.1
188
944
R29
ICPC
Respiratory symptom/complaint other
2.0
18.0
209
1093
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
17.8
1252
9984
SPAT1254
SPAT
Administration of medicine
1.5
17.7
608
4254
L08
ICPC
Shoulder symptom/complaint
1.5
17.7
690
4956
L01CA04
ATC
vinorelbine; systemic
4.5
17.3
42
95
SPAT1059
SPAT
Spirometry at the office
1.9
17.2
205
1080
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
17.2
1102
8646
J01FA09
ATC
clarithromycin; systemic
1.4
17.0
783
5798
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
17.0
1318
10654
L03
ICPC
Low back symptom/complaint
1.4
16.9
743
5457
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
16.8
1294
10446
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
16.4
441
2921
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
16.4
1017
7925
SPAT1257
SPAT
Teaching of medicine inhalation technique
2.1
16.3
146
693
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.3
16.3
1605
13421
C10AA01
ATC
simvastatin; oral
1.3
16.0
2056
17829
9050/3-C38.4
ICD-O-3
Mesothelioma, malignant of pleura, NOS
18.6
16.0
24
13
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
16.0
365
2327
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
15.7
566
3993
51101
ICD-8 Finland
Pleurisy, Adhaesiones pleurae
+∞
15.6
15
*
A02BC01
ATC
omeprazole; systemic
1.4
15.5
1000
7827
356
Kela drug reimbursment
Nintedanib and pirfenidone
4.3
15.4
39
91
J01FA15
ATC
telithromycin; oral
1.8
15.2
247
1436
R06AE07
ATC
cetirizine; oral
1.4
15.1
1059
8393
XG480
NOMESCO Finland
Histamine provocation of respiratroy tract
3.8
14.8
44
116
JN4AD
NOMESCO Finland
Body CT examination
1.5
14.8
437
2955
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
14.7
1162
9371
R01AD12
ATC
fluticasone furoate; nasal
1.4
14.7
617
4482
G04CA02
ATC
tamsulosin; oral
1.3
14.7
1774
15189
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
3.6
14.6
47
131
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
5.1
14.6
30
59
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.9
14.5
195
1070
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
5.0
14.5
31
63
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
5.8
14.4
26
45
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
14.4
1024
8125
J98.4
ICD-10 Finland
Other disorders of lung
27.3
14.3
19
7
F1246, ,
NOMESCO Finland
11.4
14.3
26
23
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
14.2
601
4367
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
14.2
636
4673
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
14.2
101
437
N06AX11
ATC
mirtazapine; oral
1.4
14.1
967
7623
N03AX16
ATC
[U] pregabalin
1.4
14.1
721
5421
WX725
NOMESCO Finland
Noninvasive ventilation
1.9
13.9
168
890
284
Kela drug reimbursment
Nintedanib and pirfenidone
4.0
13.9
39
99
N02AA01
ATC
morphine; systemic, rectal
2.4
13.8
98
423
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
13.7
806
6198
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
13.7
878
6849
M79.6
ICD-10 Finland
Pain in limb
1.3
13.6
1201
9823
8070/3-C34.3
ICD-O-3
Squamous cell carcinoma, NOS, of lower lobe, lung
4.4
13.5
33
75
C10AA05
ATC
atorvastatin; oral
1.3
13.4
1783
15391
M01AH05
ATC
etoricoxib; oral
1.3
13.2
1646
14080
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
13.1
892
7016
Z51.5
ICD-10 Finland
Palliative care
1.5
13.0
382
2578
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
13.0
1943
16998
348
Kela drug reimbursment
Roflumilast
10.1
12.9
25
25
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
12.9
1140
9308
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
12.9
732
5595
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
12.8
232
1391
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
12.8
468
3304
H02AB04
ATC
methylprednisolone; systemic
1.5
12.7
433
3015
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
12.6
1198
9875
J94.1
ICD-10 Finland
Fibrothorax
+∞
12.5
12
*
R03AL05
ATC
formoterol and aclidinium bromide; inhalant
5.2
12.5
25
48
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
9.3
12.5
25
27
R03BB05
ATC
aclidinium bromide; inhalant
5.6
12.4
23
41
AA1AD
NOMESCO Finland
CT of head and brain
1.3
12.3
1147
9423
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
3.3
12.3
46
142
M01AC06
ATC
meloxicam; systemic, rectal
1.3
12.3
1026
8304
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
12.3
299
1935
R03BB06
ATC
glycopyrronium bromide; inhalant
4.4
12.1
30
69
5010A
ICD-9 Finland
Asbestosis[ASBESTOSIS]
15.9
12.1
19
12
SPAT1053
SPAT
Memory test
1.3
12.0
813
6376
SPAT1043
SPAT
Audiometry
1.5
12.0
467
3335
P01BA02
ATC
hydroxychloroquine; oral
1.8
12.0
186
1067
GX2D5
NOMESCO Finland
Sleep oximetry
5.7
11.9
22
39
A06AH03
ATC
naloxegol; oral
2.7
11.9
62
231
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
11.9
781
6096
R81
ICPC
Pneumonia
1.9
11.9
144
765
207
Kela drug reimbursment
Chronic arrhythmias
1.3
11.9
820
6450
M01AB05
ATC
diclofenac; systemic, rectal
1.3
11.7
2003
17717
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
11.7
2793
25732
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
2.5
11.7
70
280
XQ800
NOMESCO Finland
Prick test
2.0
11.7
122
616
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.9
11.6
154
844
S18
ICPC
Laceration/cut
1.3
11.6
1684
14607
J62.0
ICD-10 Finland
Pneumoconiosis due to talc dust
22.9
11.6
16
7
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
11.5
1215
10124
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
11.5
2101
18710
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
11.5
535
3947
N07BA03
ATC
varenicline; oral
2.2
11.5
91
413
J93.0
ICD-10 Finland
Spontaneous tension pneumothorax
+∞
11.5
11
*
J93.8
ICD-10 Finland
Other pneumothorax
120.4
11.4
12
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
11.3
590
4436
R07.3
ICD-10 Finland
Other chest pain
1.5
11.3
328
2208
J37.0
ICD-10 Finland
Chronic laryngitis
2.1
11.3
107
522
L01
ICPC
Neck symptom/complaint
1.5
11.2
357
2450
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
11.2
149
817
R06AX27
ATC
desloratadine; oral
1.4
11.2
506
3715
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
11.1
707
5488
M01AE02
ATC
naproxen; oral, rectal
1.3
11.1
1576
13609
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.5
11.1
356
2448
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
4.2
11.1
29
70
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
11.0
394
2771
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
3.4
10.9
38
112
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
2.5
10.8
65
261
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
10.7
266
1731
E0000UV, ,
ATC
1.3
10.6
1218
10241
A07EC01
ATC
sulfasalazine; oral, rectal
1.7
10.5
214
1324
L17
ICPC
Foot/toe symptom/complaint
1.3
10.5
905
7331
AN1
HP
Coronary angiography
1.4
10.5
599
4569
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.5
10.5
333
2285
GAC30
NOMESCO Finland
Artificial pneumothorax
+∞
10.4
10
*
51120
ICD-8 Finland
Pleurisy, Other specified forms of effusion, except tuberculous
+∞
10.4
10
*
R01AD58
ATC
fluticasone, combinations; nasal
1.4
10.4
403
2874
GAA31
NOMESCO Finland
Thoracoscopy
7.7
10.4
23
30
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.4
10.2
407
2919
R42
ICD-10 Finland
Dizziness and giddiness
1.3
10.2
818
6558
XF402
NOMESCO Finland
ECG with work load test
1.4
10.2
437
3177
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.7
10.1
52
193
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.3
10.1
1319
11244
R78
ICPC
Acute bronchitis/bronchiolitis
2.3
10.0
72
314
XX3DW
NOMESCO Finland
Time consuming IT work
1.4
9.9
392
2809
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
1.9
9.8
112
584
RS150, ,
NOMESCO Finland
26.1
9.8
13
5
R63.4
ICD-10 Finland
Abnormal weight loss
1.7
9.8
158
920
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
9.7
509
3826
R53
ICD-10 Finland
Malaise and fatigue
1.3
9.7
767
6134
SPAT1211
SPAT
Application of soft bandage
1.5
9.6
304
2083
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
7.8
9.6
21
27
TGW99
NOMESCO Finland
Other minor procedure in thoracic surgery
8.4
9.5
20
24
J01FA10
ATC
azithromycin; systemic
1.3
9.4
1291
11048
C09CA06
ATC
candesartan; oral
1.3
9.3
686
5428
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
2.7
9.3
48
179
TGE00
NOMESCO Finland
Needle biopsy of mediastinum
4.7
9.3
21
45
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
7.3
9.2
21
29
L04AA13
ATC
[U] leflunomide
2.5
9.2
54
215
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.0
9.2
93
466
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.3
9.1
579
4482
D07AC13
ATC
mometasone; topical
1.3
9.1
877
7187
M02AA07
ATC
piroxicam; topical
1.3
9.1
1148
9723
L01EX09
ATC
nintedanib; oral
4.6
9.1
21
46
R03DX07
ATC
roflumilast; oral
8.3
9.0
19
23
XKD00
NOMESCO Finland
Uroflowmetry
1.3
9.0
1050
8805
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
9.0
1996
17949
9052/3-C38.4
ICD-O-3
Epithelioid mesothelioma, malignant of pleura, NOS
36.8
9.0
11
*
J94.2
ICD-10 Finland
Haemothorax
36.8
9.0
11
*
N40
ICD-10 Finland
Hyperplasia of prostate
1.2
9.0
1664
14686
H13
ICPC
Plugged feeling ear
1.3
9.0
804
6527
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
8.9
998
8330
J01DA01
ATC
[U] cefalexin
1.2
8.9
1975
17758
J62.8
ICD-10 Finland
Pneumoconiosis due to other dust containing silica
12.5
8.9
15
12
1240
FHL
Bronchoscopy
2.4
8.8
56
232
J84.0
ICD-10 Finland
Alveolar and parietoalveolar conditions
10.7
8.8
16
15
R74
ICPC
Upper respiratory infection acute
1.4
8.8
488
3703
UJF32
NOMESCO Finland
Coloscopy
1.3
8.7
963
8023
R05FB02
ATC
cough suppressants and expectorants; systemic
1.2
8.7
1209
10340
H02AB07
ATC
prednisone; oral
1.4
8.7
436
3254
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
8.6
399
2937
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
8.6
1074
9071
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
8.6
2543
23505
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
8.6
1155
9841
SPAT1216
SPAT
Assessment of functional ability
1.3
8.5
639
5066
B01AF02
ATC
apixaban; oral
1.3
8.5
585
4582
M25.5
ICD-10 Finland
Pain in joint
1.3
8.5
712
5729
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
2.9
8.5
39
137
J98.9
ICD-10 Finland
Respiratory disorder, unspecified
20.1
8.5
12
6
N03AX12
ATC
[U] gabapentin; oral
1.4
8.4
468
3548
SPAT1262
SPAT
Handing over of treatment supplies
1.3
8.4
710
5715
R13
ICD-10 Finland
Dysphagia
1.5
8.4
251
1701
M48.0
ICD-10 Finland
Spinal stenosis
1.4
8.4
497
3806
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.4
8.4
433
3246
I50
ICD-10 Finland
Heart failure
1.7
8.4
154
931
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
4.9
8.4
18
37
51299
ICD-8 Finland
Spontaneous pneumothorax
+∞
8.3
8
*
F2680, ,
NOMESCO Finland
8.5
8.3
17
20
WX721
NOMESCO Finland
Oxygen concentrator therapy
10.8
8.3
15
14
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
2.0
8.3
86
436
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
8.2
435
3272
D07AC01
ATC
betamethasone; topical
1.2
8.2
1149
9818
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
1.7
8.1
140
831
UKC02
NOMESCO Finland
Cystoscopy
1.3
8.1
885
7353
J01FF01
ATC
clindamycin; systemic
1.3
8.1
811
6669
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
8.1
725
5880
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.0
8.1
83
419
R01
ICPC
Pain respiratory system
2.7
8.0
42
158
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
8.9
8.0
16
18
B01AC04
ATC
clopidogrel; oral
1.3
8.0
847
7009
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
1.7
7.9
151
922
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
2.8
7.9
38
137
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.6
7.8
159
987
H25.8
ICD-10 Finland
Other senile cataract
1.3
7.8
508
3946
H25.1
ICD-10 Finland
Senile nuclear cataract
1.2
7.8
1306
11368
R01AD08
ATC
fluticasone; nasal
1.3
7.7
648
5209
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
2.5
7.7
47
191
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
7.7
596
4740
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
7.7
724
5909
SPAT1104
SPAT
Monitoring of emergency patient
1.5
7.6
236
1611
R04
ICPC
Breathing problem other
1.8
7.6
110
621
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.6
409
3085
UDC00
NOMESCO Finland
Ear microscopy
1.5
7.5
251
1741
A02BA02
ATC
ranitidine; systemic
1.3
7.5
691
5621
XX2RW, ,
NOMESCO Finland
2.7
7.5
39
147
D38.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pleura
7.1
7.5
17
24
GAC37
NOMESCO Finland
Endoscopic chemical pleurodesis
80.2
7.4
8
*
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
2.3
7.4
55
245
SPAT1060
SPAT
Administration of oxygen
3.4
7.4
25
73
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
7.3
677
5507
GD2SN
NOMESCO Finland
Lung ventilation SPECT
3.0
7.3
30
99
R09.1
ICD-10 Finland
Pleurisy
2.4
7.3
49
209
A07AA02
ATC
nystatin; oral
1.6
7.3
179
1164
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.4
7.2
291
2090
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.3
7.2
502
3932
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.5
7.2
192
1271
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.1
7.2
66
320
GX1D5
NOMESCO Finland
Flow volume spirometry
7.3
7.2
16
22
K59.09
ICD-10 Finland
Constipation, unspecified
1.4
7.2
259
1825
51998
ICD-8 Finland
Other diseases of respiratory system, Alii definiti
30.1
7.1
9
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
7.1
536
4246
H83.3
ICD-10 Finland
Noise effects on inner ear
2.2
7.1
58
269
WPB10
NOMESCO Finland
Making a convalescent care decision
3.8
7.1
21
56
GD1AA, ,
SPAT
1.6
7.1
158
1005
I95.1
ICD-10 Finland
Orthostatic hypotension
1.5
7.1
193
1285
ZYY98
NOMESCO Finland
Missed treatment contact, no notification given by patient
8.8
7.0
14
16
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
7.0
263
1865
SPAT1283
SPAT
Restricted health certificate
1.7
7.0
136
835
N02AA05
ATC
oxycodone; systemic
1.3
7.0
719
5924
D07XC01
ATC
betamethasone; topical
1.3
6.9
413
3164
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.4
6.9
324
2389
R04.0
ICD-10 Finland
Epistaxis
1.4
6.9
322
2374
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
6.9
1085
9359
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
6.8
1639
14713
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
6.8
377
2858
R09.3
ICD-10 Finland
Abnormal sputum
2.4
6.8
46
197
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
1.8
6.7
93
520
M01AX17
ATC
nimesulide; oral
1.2
6.7
760
6328
M54
ICD-10 Finland
Dorsalgia
1.4
6.6
252
1792
GX2C5
NOMESCO Finland
Short-lasting oximetry
5.5
6.6
18
33
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.5
6.6
196
1330
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
3.2
6.6
25
79
L04AX05
ATC
pirfenidone; oral
3.5
6.6
22
64
XG499
NOMESCO Finland
Other fysiological examination of respiatory function
6.2
6.5
16
26
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
6.4
602
4902
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
1.8
6.4
95
543
S29
ICPC
Skin symptom/complaint other
1.3
6.4
587
4769
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.5
6.4
172
1144
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
1.5
6.3
215
1498
SPAT1081
SPAT
Cardiorespiratory global assessment
1.4
6.3
225
1582
M01AH02
ATC
rofecoxib; oral
1.3
6.3
402
3112
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
3.2
6.3
24
76
GAC46
NOMESCO Finland
Partial decortication of pleura
9.3
6.3
12
13
J60
ICD-10 Finland
Coalworker pneumoconiosis
+∞
6.2
6
*
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.3
6.2
356
2711
E000001, ,
ATC
1.3
6.2
535
4309
A04
ICPC
Weakness/tiredness general
1.3
6.2
449
3536
L15
ICPC
Knee symptom/complaint
1.3
6.2
614
5031
D82
ICPC
Teeth/gum disease
1.2
6.2
794
6696
L04AX03
ATC
methotrexate; systemic
1.5
6.2
209
1455
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.4
6.2
330
2487
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.4
6.2
253
1825
H81
ICPC
Excessive ear wax
1.2
6.2
716
5973
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
6.2
1433
12790
R84
ICPC
Malignant neoplasm bronchus/lung
3.3
6.1
22
67
WX892
NOMESCO Finland
Monitored bed care
1.4
6.1
273
2000
A03
ICPC
Fever
1.4
6.1
317
2380
A01AB09
ATC
miconazole; local oral
1.4
6.1
229
1628
-31
ICPC
Medical examin/health eval partial
1.4
6.0
226
1604
I48.1
ICD-10 Finland
Persistent atrial fibrillation
1.5
6.0
186
1272
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
1.8
6.0
91
523
WX722
NOMESCO Finland
PEEP
1.5
6.0
160
1061
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.5
6.0
152
997

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
140
115
12.59
141.74
1.4
1.1
13.95
14.58
u/l
0.08
131
89
591
2042
3.23
132.51
1.5
1.4
—
—
—
0
0
75
30
25.47
107.28
1.5
1.1
57.98
37.80
ug/l
0.20
43
12
182
320
5.92
99.18
1.4
1.2
35.70
26.32
g/l
15.56
170
254
2048
13834
2.00
96.72
6.7
5.9
—
—
—
0
0
145
209
7.17
95.83
1.6
1.2
—
—
—
0
0
218
466
4.89
95.58
3.0
2.6
—
—
—
0
0
224
492
4.77
95.05
2.2
2.3
—
—
—
0
0
2169
15259
1.94
87.59
5.6
5.4
0.21
0.21
e9/l
0.22
1941
13035
2108
14760
1.92
85.57
5.4
5.2
0.68
0.65
e9/l
6.00
1855
12461
144
233
6.38
85.27
1.4
1.2
—
—
—
0
0
2112
14825
1.92
84.78
5.4
5.2
0.04
0.04
e9/l
1.20
1862
12528
2121
15101
1.88
79.45
5.5
5.3
1.84
1.91
e9/l
0.66
1908
13015
156
303
5.32
76.26
1.4
1.2
3777.30
3136.13
e6/l
0.11
133
196
67
47
14.49
74.19
1.4
1.1
4.06
3.44
mmol/l
0.38
62
40
92
115
8.17
68.72
1.2
1.1
—
—
—
0
0
1954
13951
1.80
68.68
5.9
5.5
2.89
2.92
%
0.23
1826
12793
1986
14250
1.80
68.62
6.1
5.8
24.06
25.15
%
4.29
1854
13114
1962
14029
1.80
68.58
6.4
5.9
9.34
9.09
%
2.35
1832
12887
1907
13550
1.79
67.84
5.8
5.5
0.64
0.62
%
0.40
1779
12425
140
275
5.24
67.55
1.4
1.2
142278.04
21673.15
e6/l
2.09
89
145
533
2445
2.37
66.27
4.6
3.3
7.42
7.42
ph
0.07
67
275
549
2552
2.34
66.21
4.0
4.4
—
—
—
0
0
536
2481
2.34
65.22
4.7
3.3
5.29
5.01
kpa
10.17
506
2307
2730
21875
1.81
61.49
5.5
4.0
16.16
14.23
mm/h
6.67
2502
19745
1929
14020
1.74
61.11
5.7
5.5
60.00
59.18
%
2.19
1797
12901
2259
17207
1.74
60.00
7.7
8.2
4.64
4.47
e9/l
1.75
2014
14794
111
205
5.54
57.31
1.3
1.2
5.97
7.11
mmol/l
2.77
106
188
1730
12348
1.72
57.27
3.8
3.1
1687.41
1938.54
ng/l
2.01
1516
10782
408
1774
2.45
56.77
4.7
3.4
—
—
—
0
0
436
2019
2.30
52.44
1.7
1.5
—
—
—
0
0
1873
13920
1.66
51.29
5.2
4.2
47.88
81.24
ng/l
1.67
1597
11333
288
1125
2.68
49.90
1.3
1.3
314.44
332.19
u/ml
0.08
267
1007
56
56
10.13
49.58
1.4
1.2
3.01
3.22
%
0.04
49
45
2174
16938
1.63
48.12
6.1
6.2
12.91
13.22
umol/l
0.40
2043
16065
542
2847
2.05
47.09
1.3
1.2
445.99
422.85
titre
0.14
147
576
342
1499
2.40
46.46
5.3
3.6
25.19
24.47
mmol/l
4.05
317
1345
62
78
8.06
46.05
1.4
1.2
74.27
58.00
%
2.18
55
56
2307
18383
1.62
45.37
22.6
21.4
1.40
1.44
inr
0.91
699
5073
219
807
2.81
42.38
3.9
3.2
—
—
—
0
0
2007
15644
1.58
41.86
6.2
6.0
1.20
1.20
mmol/l
0.06
1787
14068
2840
24098
1.64
40.72
8.3
7.6
82.13
81.56
u/l
0.20
2674
22517
207
778
2.75
38.56
4.7
3.8
2.57
2.35
mmol/l
0.59
148
490
207
778
2.75
38.56
4.7
3.8
5.01
4.86
kpa
1.80
201
757
207
781
2.74
38.27
4.7
3.8
8.13
8.43
kpa
1.94
201
759
1384
10049
1.58
38.22
2.8
2.5
60.07
69.16
u/l
0.57
1259
9252
189
683
2.86
37.90
1.2
1.1
0.29
0.27
u/ml
0.12
17
68
2134
17171
1.53
36.44
6.8
6.8
1.20
1.21
mmol/l
0.33
1680
14507
719
4496
1.73
35.43
5.8
6.3
1.79
0.77
mmol/l
8.81
576
3420
221
900
2.54
35.04
4.7
3.7
7.42
7.42
ph
0.09
208
801
598
3559
1.80
34.92
1.2
1.2
44.05
41.39
iu/ml
0.13
186
1008
96
239
4.09
34.64
1.3
1.2
—
—
—
0
0
717
4507
1.72
34.59
5.8
6.3
5.16
4.95
kpa
5.90
683
4271
466
2572
1.92
34.54
4.4
4.0
—
—
—
0
0
716
4506
1.72
34.37
5.8
6.3
10.73
11.96
kpa
10.99
688
4266
552
3228
1.83
34.10
2.2
2.6
67.06
66.10
g/l
2.26
490
2865
1417
10618
1.52
32.63
5.3
4.5
—
—
—
0
0
2022
16409
1.48
30.91
3.6
3.1
58.70
59.03
u/l
0.05
1792
14710
553
3332
1.77
30.69
1.2
1.2
14.18
16.03
u/ml
0.17
167
1072
652
4121
1.70
30.46
5.9
6.5
94.58
95.49
%
2.89
634
3951
2377
20031
1.47
29.20
5.4
4.8
6.88
6.99
mmol/l
1.77
2263
18893
3209
28860
1.61
28.42
22.4
18.0
27.13
30.28
mg/l
5.65
2845
23972
2520
21599
1.46
27.47
4.9
4.4
—
—
—
0
0
162
640
2.60
27.34
1.6
1.7
11.18
13.44
mg/l
1.45
146
581
185
780
2.44
27.22
2.9
2.3
15.85
15.99
%
0.17
94
413
432
2512
1.81
26.85
6.5
6.4
24.94
24.03
mmol/l
5.94
420
2383
139
520
2.73
26.14
3.1
3.3
59.55
59.40
%
0.05
139
520
643
4239
1.62
25.07
5.3
5.0
33.38
33.10
%
0.24
420
2786
327
1779
1.91
25.04
1.7
1.8
1.27
2.72
ug/l
2.50
286
1532
409
2405
1.78
24.40
3.7
3.7
0.33
0.36
%
0.04
125
755
1122
8398
1.47
24.32
4.5
4.1
0.00
0.00
estimate
0.50
410
2515
1426
11191
1.43
23.92
4.5
4.3
—
—
—
0
0
2323
19872
1.41
23.71
3.6
3.3
15.41
15.09
pmol/l
7.30
1976
17327
2885
25669
1.47
23.70
4.6
4.2
2.11
2.11
mu/l
0.03
2468
22559
2461
21298
1.42
23.29
5.4
4.8
125.24
1345.05
e6/l
2.61
50
403
427
2576
1.74
23.26
3.6
3.7
0.17
0.11
%
0.73
141
903
408
2436
1.75
23.05
3.5
3.7
0.55
0.67
%
0.72
144
886
3203
29187
1.53
22.63
22.8
17.8
—
—
—
0
0
560
3659
1.62
22.47
4.6
4.5
—
—
—
0
0
444
2734
1.70
22.42
3.7
3.7
1.15
0.90
%
0.80
160
1053
218
1069
2.10
22.35
1.6
1.5
305.45
128.16
titre
0.83
11
49
838
6022
1.50
21.92
1.6
1.6
1.29
1.69
mg/l
3.84
667
4732
211
1034
2.10
21.67
3.5
2.7
25.58
24.20
mmol/l
4.64
205
1007
182
842
2.22
21.63
2.4
2.1
128.43
127.54
g/l
0.14
114
616
454
2842
1.68
21.52
3.6
3.9
1.21
1.22
mmol/l
2.63
392
2450
118
449
2.68
21.52
2.1
1.8
87.84
89.15
%
1.13
118
444
1085
8242
1.44
21.19
2.0
1.8
1171.99
1130.86
nmol/l
0.74
760
6112
1032
7840
1.43
19.93
1.8
1.8
409.52
21555963.58
pmol/l
4.62
776
6300
52
133
3.95
18.21
1.1
1.1
—
—
—
0
0
361
2229
1.68
17.92
2.2
2.2
357.54
376.83
nmol/l
1.01
329
2015
3262
30212
1.47
17.64
13.2
11.3
24.99
25.57
u/l
0.65
3101
28721
3310
30754
1.48
17.51
26.4
22.2
4.07
4.03
mmol/l
11.61
3204
29840
3307
30722
1.48
17.50
26.3
22.0
139.28
139.64
mmol/l
11.35
3210
29851
626
4419
1.50
17.46
10.3
8.8
—
—
—
0
0
330
2018
1.69
16.97
2.4
2.6
11.22
10.77
g/l
0.90
294
1824
47
120
3.95
16.52
1.3
1.4
4.09
2.62
u/ml
0.22
27
74
974
7529
1.39
16.49
3.9
3.7
—
—
—
0
0
1767
14964
1.33
16.47
4.8
4.9
33.56
34.36
g/l
6.71
1602
13749
27
19
14.30
16.29
1.3
1.2
13.71
25.50
%
0.80
21
14
115
495
2.36
16.26
1.2
1.3
—
—
—
0
0
337
2097
1.66
16.21
6.3
6.3
25.13
24.38
mmol/l
2.44
331
2076
1744
14777
1.32
16.05
4.3
3.8
0.00
0.00
estimate
1.98
475
3009
1731
14666
1.32
15.87
5.3
5.1
0.00
0.00
estimate
-0.00
457
2755
3320
31038
1.45
15.34
32.7
26.9
39.75
39.52
%
1.18
2960
28281
3320
31043
1.45
15.27
32.6
26.8
233.77
226.17
e9/l
8.65
3216
29974
1448
12008
1.33
15.27
2.9
2.9
184.27
180.45
ug/l
0.16
1246
10716
153
759
2.06
15.27
3.4
2.5
—
—
—
0
0
3320
31045
1.45
15.25
32.4
26.7
30.63
30.65
pg
0.23
3244
30357
3320
31046
1.45
15.24
32.6
26.8
4.38
4.41
e12/l
1.67
3193
29837
3320
31046
1.45
15.24
32.5
26.7
92.35
92.09
fl
2.30
3243
30357
1750
14907
1.31
15.21
4.3
3.8
0.00
0.00
estimate
-0.00
432
2626
3320
31052
1.45
15.16
32.6
26.8
7.37
7.07
e9/l
6.33
3202
29843
3320
31052
1.45
15.16
32.8
27.0
133.23
134.06
g/l
2.20
3241
30362
118
532
2.26
15.01
1.2
1.1
57.19
55.72
u/ml
—
9
16
531
3734
1.49
14.94
6.6
7.0
125.45
120.10
g/l
7.62
518
3628
266
1593
1.72
14.76
1.7
1.9
1.19
1.46
g/l
0.70
236
1415
112
506
2.25
14.20
1.2
1.1
5.80
6.02
u/ml
0.02
17
62
111
501
2.25
14.10
1.3
1.1
22.94
3.20
u/ml
0.50
15
42
3079
28528
1.37
14.00
5.9
5.6
2.37
2.40
mmol/l
0.98
2632
25498
1334
11035
1.32
14.00
2.8
3.3
2.34
2.34
mmol/l
0.01
1132
9434
27
50
5.43
13.99
1.2
1.0
1.55
1.33
mmol/l
0.23
20
16
2978
27474
1.35
13.76
7.3
7.1
41.49
41.57
mmol/mol
0.19
2575
24756
1305
10784
1.31
13.73
2.3
2.2
221.05
236.94
u/l
0.25
1202
10033
2963
27323
1.34
13.67
5.3
4.9
1.33
1.34
mmol/l
0.20
2516
24318
60
205
2.96
13.49
1.4
1.2
—
—
—
0
0
25
23
10.93
13.48
1.3
1.1
3.47
4.30
%
—
15
10
2989
27631
1.34
13.33
5.3
4.9
4.13
4.17
mmol/l
1.14
2572
24812
2881
26492
1.33
13.32
4.6
4.4
1.25
1.24
mmol/l
0.30
2431
23321
3052
28311
1.35
13.23
5.9
5.4
6.12
6.21
mmol/l
3.89
2605
24939
59
204
2.92
13.00
1.4
1.2
7.35
6.85
g/l
0.45
35
146
59
204
2.92
13.00
1.4
1.2
2.94
3.05
g/l
0.16
36
148
59
204
2.92
13.00
1.4
1.2
0.50
0.44
g/l
0.41
38
146
420
2915
1.49
12.52
2.2
2.4
—
—
—
0
0
76
306
2.51
12.50
1.3
1.2
—
—
—
0
0
1213
10029
1.30
12.43
4.0
4.0
7.40
7.40
ph
0.08
328
1825
446
3143
1.47
12.31
3.7
3.4
—
—
—
0
0
632
4770
1.39
11.92
1.9
2.0
—
—
—
0
0
719
5550
1.36
11.78
3.1
2.9
0.81
0.81
mmol/l
0.15
662
5148
2469
22396
1.28
11.72
6.0
5.8
3.49
4.35
ug/l
0.87
2104
19761
80
345
2.35
11.37
1.4
1.5
0.80
1.06
g/l
1.00
55
262
311
2068
1.55
11.32
6.7
7.9
25.25
23.94
mmol/l
8.39
296
1980
1323
11182
1.28
11.14
2.1
2.1
77.92
78.08
nmol/l
0.07
1104
9572
243
1531
1.63
11.13
5.0
4.5
—
—
—
0
0
20
35
5.74
11.00
1.2
1.0
0.38
0.78
mmol/l
0.43
15
13
1114
9227
1.29
10.98
3.4
3.1
2670.70
6909.77
umol/l
3.93
876
7783
551
4127
1.39
10.81
1.5
1.5
3.10
2.87
g/l
0.98
330
2321
465
3403
1.42
10.43
1.5
1.4
—
—
—
0
0
1376
11790
1.26
10.07
4.0
3.5
5.72
5.77
ph
0.11
23
351
198
1216
1.66
10.05
5.6
5.5
1.33
1.40
mmol/l
0.59
184
1082
1153
9693
1.27
9.88
2.4
2.3
3.16
3.03
mg/l
0.93
944
8089
520
3918
1.38
9.80
2.3
2.5
67.45
66.49
e9/l
0.24
419
3040
713
5639
1.32
9.76
2.5
2.5
2.24
2.22
g/l
0.41
622
5160
118
629
1.90
9.71
1.7
1.3
0.23
0.24
g/l
0.04
111
596
751
6019
1.31
9.29
2.5
2.6
12.26
12.20
umol/l
0.06
673
5535
120
658
1.85
9.08
1.8
1.3
1.08
1.16
g/l
1.93
112
624
33
101
3.29
9.02
2.0
1.5
1.20
-0.41
mmol/l
1.62
28
93
1369
11861
1.24
8.75
2.4
2.3
—
—
—
0
0
541
4176
1.34
8.69
1.3
1.3
—
—
—
0
0
218
1422
1.56
8.68
3.9
3.7
1.37
1.50
mmol/l
0.87
213
1399
674
5371
1.31
8.65
2.6
2.6
21.77
22.10
%
0.21
545
4486
279
1928
1.48
8.49
3.2
3.3
4.70
6.03
e9/l
1.18
182
1398
97
508
1.93
8.47
2.1
1.9
34.44
28.01
mg/l
0.41
25
119
45
172
2.64
8.35
2.2
2.1
—
—
—
0
0
485
3706
1.35
8.31
3.7
2.9
202.41
262.28
ng/l
3.48
454
3427
1091
9266
1.25
8.28
1.7
1.6
20.45
19.17
nmol/l
0.64
888
7827
147
882
1.69
8.21
5.8
6.3
104.68
105.37
mmol/l
1.06
139
785
147
882
1.69
8.21
5.7
6.3
11.31
11.51
mmol/l
0.35
139
785
51
212
2.42
7.98
2.2
2.4
7.43
7.42
ph
0.80
31
55
501
3876
1.34
7.90
2.9
4.2
19.97
22.96
ug/l
0.14
436
3284
611
4861
1.30
7.89
4.8
5.7
1.03
1.03
mmol/l
0.09
552
4474
568
4481
1.31
7.80
1.2
1.2
2.00
1.98
u/ml
0.01
135
1071
2042
22247
0.83
7.63
30.2
24.8
331.52
332.30
g/l
3.64
2018
21976
153
947
1.64
7.61
3.3
3.0
0.82
0.81
nmol/l
0.02
117
717
156
971
1.63
7.59
1.5
1.6
—
—
—
0
0
867
7259
1.25
7.35
3.7
3.7
—
—
—
0
0
1461
12958
1.20
6.96
13.1
10.3
0.00
0.00
e9/l
0.62
1231
10559
17
39
4.37
6.95
1.2
1.1
—
—
—
0
0
320
2355
1.39
6.93
1.9
2.1
154.19
178.38
ug/g
0.60
230
1826
355
2665
1.37
6.81
1.4
1.3
—
—
—
0
0
1032
8910
1.21
6.41
3.5
3.1
37.17
38.32
u/l
0.15
955
8364
87
486
1.81
6.32
1.4
1.2
—
—
—
0
0
937
8046
1.22
6.11
3.2
2.8
3.24
3.26
e6/l
0.02
857
7233
203
1410
1.46
6.09
2.7
3.3
5.17
3.57
ratio
0.23
12
95
78
427
1.84
6.06
1.4
1.5
67.18
66.63
%
0.04
45
267
207
1447
1.45
6.01
2.7
3.3
43.70
53.63
mg/l
0.68
158
1193
1676
15203
1.18
5.88
2.3
2.2
92.76
90.43
pmol/l
1.19
937
8481
21
64
3.29
5.85
1.0
1.1
—
—
—
0
0
21
64
3.29
5.85
1.0
1.1
—
—
—
0
0
21
64
3.29
5.85
1.0
1.1
—
—
—
0
0
73
397
1.85
5.81
4.2
3.2
55.36
58.52
%
0.57
59
321
206
1449
1.44
5.80
2.7
3.3
58.10
66.71
mg/l
0.48
157
1190
47
219
2.16
5.74
1.4
1.1
108.26
51.04
u/ml
—
7
7
623
5159
1.25
5.72
2.3
2.3
1.75
1.72
%
0.35
525
4467
478
3844
1.28
5.62
3.0
2.4
5.89
6.94
ug/l
0.98
402
3328
79
446
1.79
5.59
2.2
2.7
—
—
—
0
0
28
104
2.70
5.58
1.0
1.0
—
—
—
0
0
327
2507
1.33
5.49
1.3
1.5
—
—
—
0
0
62
327
1.91
5.44
1.3
1.1
28.76
40.80
u/ml
—
5
20
1642
14944
1.17
5.37
2.7
2.8
—
—
—
0
0
11
15
7.35
5.14
1.5
1.4
—
—
—
0
0
465
3769
1.27
5.13
5.8
6.4
11.27
11.67
mmol/l
0.52
430
3539
36
158
2.29
5.11
1.4
1.4
3.70
3.74
%
—
10
34
103
643
1.62
5.08
4.2
3.3
1.36
1.71
%
0.39
92
550
260
1954
1.35
5.00
2.6
2.5
—
—
—
0
0
48
239
2.02
4.99
2.0
2.0
1.08
1.08
e9/l
0.01
42
216
389
3096
1.28
4.98
2.2
2.1
0.19
0.20
g/l
1.18
346
2838
132
883
1.51
4.83
1.4
1.5
271.25
253.95
ug/g
0.47
83
557
180
1284
1.42
4.75
2.7
2.9
0.35
0.32
g/l
0.28
72
553
228
1693
1.37
4.75
4.8
4.8
0.91
0.86
%
1.34
216
1585
416
3358
1.27
4.75
6.1
6.1
1.39
1.43
mmol/l
0.28
408
3250
2519
23820
1.16
4.68
23.8
21.5
16.36
15.59
%
5.76
2470
23307
231
1730
1.36
4.57
4.7
4.7
1.74
1.59
%
2.01
220
1619
319
2509
1.30
4.49
3.8
4.0
96.97
105.76
ng/l
0.90
261
2144
71
418
1.71
4.42
5.9
3.7
—
—
—
0
0
190
1388
1.39
4.40
2.1
2.2
390.30
611.68
ug/l
0.97
168
1321
278
2154
1.31
4.38
9.0
8.4
—
—
—
0
0
49
260
1.90
4.30
1.1
1.2
—
—
—
0
0
30
134
2.25
4.14
2.0
1.4
—
—
—
0
0
91
1390
0.65
4.14
2.8
3.4
83.51
3048.10
u/ml
0.91
74
1193
31
141
2.21
4.11
1.2
1.1
1.06
1.17
u/ml
0.06
15
73
152
1086
1.42
4.03
2.8
3.6
—
—
—
0
0
104
694
1.51
3.92
1.7
2.2
—
—
—
0
0
39
198
1.98
3.91
1.2
1.2
—
—
—
0
0
59
344
1.73
3.85
1.4
1.4
26.25
23.04
%
0.29
38
219
27
120
2.26
3.80
1.0
1.0
1.06
2.63
u/ml
—
5
58
22
89
2.48
3.79
2.3
2.0
—
—
—
0
0
1111
10026
1.15
3.75
3.3
3.3
—
—
—
0
0
2288
21655
1.14
3.72
5.6
4.6
—
—
—
0
0
25
109
2.30
3.68
1.0
1.1
—
—
—
0
0
852
7551
1.16
3.67
1.7
1.6
1.31
1.27
mmol/l
0.28
633
6158
27
122
2.22
3.66
1.0
1.0
0.96
0.76
u/ml
—
5
59
72
450
1.61
3.64
1.3
1.4
11.51
8.43
u/l
1.49
54
360
32
156
2.06
3.60
1.9
2.0
0.24
0.25
e9/l
0.11
26
141
25
111
2.26
3.54
1.0
1.1
—
—
—
0
0
1263
11557
1.14
3.42
3.4
3.3
678.72
323.98
mg/l
1.32
814
7899
204
1581
1.31
3.28
1.1
1.2
—
—
—
0
0
17
66
2.58
3.21
1.1
1.1
0.50
2.29
u/ml
—
6
30
22
97
2.28
3.19
2.4
2.0
7.91
5.49
%
0.31
22
89
43
243
1.78
3.18
3.0
3.0
—
—
—
0
0
89
607
1.48
3.10
1.2
1.2
—
—
—
0
0
681
6008
1.16
3.09
1.8
1.9
30.75
30.37
s
0.71
654
5824
1158
10600
1.13
3.06
2.5
2.7
—
—
—
0
0
86
586
1.48
3.02
1.4
1.3
59.64
64.13
mmol/l
0.49
69
473
184
1425
1.31
3.00
1.2
1.2
—
—
—
0
0
1256
11569
1.13
2.99
3.3
3.2
7.62
7.71
mmol/l
0.37
988
9415
859
7743
1.14
2.87
3.4
3.2
548.58
573.67
mosm/kgh2o
3.02
756
6643
170
1314
1.31
2.83
1.2
1.3
—
—
—
0
0
396
3368
1.20
2.81
1.4
1.3
—
—
—
0
0
174
1352
1.30
2.79
1.3
1.3
—
—
—
0
0
127
945
1.36
2.75
1.1
1.1
61.22
111.65
iu/ml
1.63
40
283
31
167
1.86
2.71
1.9
2.0
553.33
517.43
e6/l
0.15
24
143
1058
9710
1.12
2.63
3.8
3.5
—
—
—
0
0
45
274
1.65
2.61
1.7
1.4
—
—
—
0
0
258
2121
1.23
2.60
1.4
1.5
—
—
—
0
0
7
15
4.67
2.59
3.1
1.1
—
—
—
0
0
71
482
1.48
2.58
1.3
1.4
—
—
—
0
0
70
474
1.49
2.58
2.8
3.5
—
—
—
0
0
301
2519
1.21
2.55
1.5
1.5
—
—
—
0
0
113
838
1.36
2.53
2.5
2.6
1.81
1.80
mg/l
0.06
101
716
20
95
2.11
2.48
1.5
1.4
77.89
66.46
umol/l
—
9
59
49
311
1.58
2.43
1.2
1.3
238.46
256.63
pmol/l
0.20
41
251
1114
10295
1.11
2.42
3.8
3.5
0.58
0.46
e6/l
0.59
902
8148
16
70
2.29
2.41
1.1
1.1
5.00
1.15
u/ml
—
7
36
87
624
1.40
2.39
1.1
1.2
448.00
110.23
titre
—
5
43
88
633
1.40
2.38
1.4
1.4
—
—
—
0
0
751
6789
1.13
2.38
5.0
4.2
1.02
1.02
kg/l
0.01
109
1069
1314
12260
1.11
2.38
4.0
3.9
11.53
9.39
mg/mmol
0.80
832
8143
44
275
1.61
2.34
1.4
1.3
—
—
nmol/l
—
0
0
104
776
1.35
2.27
2.4
2.4
32.00
34.17
umol/l
0.24
91
667
11
41
2.69
2.20
1.6
1.6
45.09
46.41
umol/l
0.07
11
41
251
2099
1.21
2.19
3.5
3.4
25.81
24.74
mmol/l
4.36
240
2033
453
3984
1.15
2.17
1.8
1.8
—
—
—
0
0
261
2194
1.20
2.16
1.3
1.5
—
—
—
0
0
545
6074
0.88
2.05
3.6
3.4
1.13
1.07
e6/l
0.09
319
3657
32
192
1.67
2.02
1.0
1.2
1.10
1.20
promille
0.14
23
153
101
768
1.32
1.98
1.3
1.2
—
—
—
0
0
373
3259
1.16
1.97
7.4
7.3
—
—
—
0
0
165
1339
1.24
1.95
2.0
1.9
—
—
—
0
0
28
164
1.71
1.94
4.1
3.4
—
—
—
0
0
255
2171
1.19
1.87
1.6
1.7
1.50
1.53
g/l
0.23
214
1843
18
93
1.94
1.84
1.0
1.1
—
—
—
0
0
5
12
4.17
1.82
1.0
1.4
—
—
—
0
0
37
238
1.56
1.81
1.3
1.6
—
1964.44
—
0
9
11
47
2.34
1.77
1.0
1.3
35.85
1739.96
ng/l
—
6
34
34
216
1.58
1.76
1.8
1.8
6.96
7.22
mmol/l
0.25
29
148
19
102
1.87
1.76
1.2
1.2
8.17
8.96
ug/l
0.15
19
89
265
2280
1.17
1.73
3.4
3.0
—
—
—
0
0
18
96
1.88
1.70
1.3
2.2
—
—
—
0
0
1318
12475
1.09
1.65
4.4
4.1
123.14
106.78
e6/l
0.21
1031
9536
102
800
1.28
1.65
3.0
3.2
1469.28
890.56
u/ml
0.25
94
738
42
286
1.47
1.61
1.5
1.3
—
—
—
0
0
5
14
3.57
1.61
1.0
1.4
—
—
—
0
0
5
14
3.57
1.61
1.2
1.1
—
—
—
0
0
872
8116
1.10
1.60
2.5
2.6
—
—
—
0
0
195
1647
1.19
1.60
1.2
1.3
—
—
—
0
0
34
224
1.52
1.54
1.4
1.3
—
—
—
0
0
5
15
3.34
1.52
1.0
1.1
—
—
—
0
0
133
1090
1.23
1.50
2.2
2.2
107.48
104.97
ug/min
0.04
64
628
18
101
1.79
1.48
1.5
2.2
—
—
—
0
0
53
385
1.38
1.47
1.0
1.1
—
—
—
0
0
65
488
1.34
1.47
23.5
23.3
7.81
7.67
mmol/l
0.10
52
381
425
3835
1.12
1.44
4.1
3.7
2.60
1.65
mmol/l
6.69
358
3140
425
3843
1.12
1.39
4.1
3.7
6.04
5.75
kpa
5.18
412
3713
6
139
0.43
1.39
1.3
1.2
5.77
6.39
mmol/l
—
6
132
17
96
1.77
1.38
1.1
1.1
0.69
0.49
u/ml
—
8
58
26
167
1.56
1.34
1.3
1.3
1.36
1.10
nmol/l
0.59
19
122
43
307
1.41
1.34
1.5
1.5
—
—
—
0
0
10
47
2.13
1.33
1.6
1.5
—
—
—
0
0
1198
11383
1.08
1.32
4.0
3.6
150.32
128.95
e6/l
0.10
972
9098
251
2847
0.87
1.30
3.0
2.4
32.72
37.87
u/l
1.14
204
2403
47
343
1.37
1.30
1.3
1.3
62.65
66.47
mu/l
0.05
38
295
43
311
1.39
1.26
1.6
1.3
271.65
279.28
mosm/kgh2o
1.22
34
227
34
236
1.44
1.24
1.1
1.1
37.82
35.60
mmol/l
0.24
26
204
84
676
1.25
1.18
1.2
1.3
25.02
41.52
u/l
2.02
69
591
0
33
0.00
1.16
0.0
1.2
—
—
—
0
0
35
249
1.41
1.14
6.6
13.0
—
—
—
0
0
14
80
1.75
1.12
1.3
1.2
—
—
—
0
0
14
80
1.75
1.12
1.1
1.2
21.00
32.20
%
—
8
50
282
2527
1.12
1.12
3.5
3.3
129.56
127.19
g/l
1.06
275
2455
481
4438
1.10
1.10
1.4
1.4
—
—
—
0
0
176
1531
1.16
1.09
2.2
2.3
2.84
2.93
g/l
0.72
151
1342
12
66
1.82
1.09
1.9
1.5
—
—
—
0
0
65
514
1.27
1.07
3.2
2.4
1.70
1.25
g/24h
0.44
30
251
11
193
0.57
1.07
1.3
1.4
16.80
15.75
umol/l
0.11
11
177
178
1559
1.15
1.02
2.3
2.3
10.53
10.27
g/l
0.33
156
1356
103
865
1.20
1.00
1.5
1.6
11931.88
17634.41
e6/l
1.10
76
604
5
23
2.18
0.98
1.0
1.2
—
—
—
0
0
5
23
2.18
0.98
1.0
1.2
—
—
—
0
0
5
23
2.18
0.98
1.0
1.2
—
—
—
0
0
19
283
0.67
0.96
1.0
1.0
240.57
317.24
ng/l
0.88
14
172
0
32
0.00
0.95
0.0
8.2
—
7.30
—
0
24
19
282
0.67
0.94
1.0
1.0
506.36
641.08
ng/l
0.86
14
168
16
246
0.65
0.94
2.0
1.5
—
—
—
0
0
164
1440
1.14
0.93
1.2
1.3
23.29
72.11
au/ml
—
7
82
25
175
1.43
0.92
1.2
1.3
—
—
—
0
0
340
3122
1.10
0.90
2.1
2.0
11.79
11.48
nmol/l
0.25
271
2645
20
135
1.48
0.89
1.0
1.1
—
—
—
0
0
89
748
1.19
0.88
1.3
1.5
—
—
—
0
0
88
1043
0.84
0.87
1.6
1.9
20.75
21.95
s
1.87
76
956
50
395
1.27
0.87
1.1
1.2
—
—
—
0
0
701
6637
1.07
0.86
2.8
3.2
2.46
2.45
mmol/l
1.61
619
5750
188
1677
1.13
0.86
2.2
2.2
7.56
7.34
g/l
0.83
165
1483
99
844
1.18
0.84
1.1
1.1
83.00
256.63
titre
—
5
16
6
31
1.94
0.84
1.7
2.2
50.00
64.76
%
—
6
21
187
1672
1.12
0.83
2.2
2.2
3.79
3.73
g/l
0.15
165
1483
48
382
1.26
0.81
1.7
1.7
4.43
4.31
mmol/24h
0.09
40
332
18
122
1.48
0.80
1.7
1.5
1.04
0.84
g/l
1.22
18
122
23
164
1.40
0.79
1.0
1.1
—
—
—
0
0
54
437
1.24
0.79
1.3
1.2
—
—
—
0
0
41
321
1.28
0.79
2.1
1.8
215.12
291.92
mu/l
3.05
33
302
755
7192
1.06
0.78
5.3
4.2
175.84
620.08
ng/l
3.23
668
6448
51
411
1.24
0.78
1.2
1.1
—
—
—
0
0
1846
18008
1.05
0.76
5.2
5.0
20.94
22.25
%
3.75
1026
9951
23
166
1.39
0.75
1.1
1.1
—
—
—
0
0
31
236
1.32
0.74
1.9
2.0
493.10
491.37
min
0.03
20
163
201
2215
0.90
0.73
3.0
3.1
—
—
—
0
0
784
7494
1.06
0.73
5.9
6.2
—
—
—
0
0
9
56
1.61
0.72
5.3
4.9
—
—
—
0
0
61
507
1.21
0.71
1.8
1.8
175.26
194.54
pmol/l
1.00
54
457
25
185
1.35
0.71
3.0
1.7
96.32
108.89
umol/l
0.93
25
185
23
168
1.37
0.71
2.9
2.6
38.46
32.93
%
0.79
13
101
5
26
1.92
0.70
1.2
1.3
—
—
—
0
0
5
26
1.92
0.70
1.0
1.0
—
—
—
0
0
141
1257
1.13
0.69
2.0
2.1
37.27
37.09
g/l
0.17
117
1064
27
353
0.76
0.68
2.6
3.4
24.79
29.28
mg/l
0.15
20
284
31
397
0.78
0.68
1.4
1.4
—
—
—
0
0
23
170
1.36
0.67
2.3
2.2
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
18
128
1.41
0.65
1.1
1.1
—
—
—
0
0
5
29
1.73
0.64
1.2
1.2
—
—
—
0
0
82
710
1.16
0.63
1.6
1.7
47.49
48.59
nmol/l
0.19
77
662
12
79
1.52
0.62
1.3
1.4
—
—
—
0
0
613
6421
0.95
0.62
3.3
3.1
1.30
1.06
e6/l
0.64
385
3961
19
138
1.38
0.62
1.2
1.1
—
—
—
0
0
57
675
0.84
0.62
1.2
1.3
527.35
611.88
mg/l
0.62
52
619
95
833
1.14
0.62
1.1
1.1
—
1.63
—
0
12
18
130
1.39
0.61
1.2
1.1
42.66
41.25
g/l
—
10
63
784
8154
0.95
0.61
4.4
4.1
77.94
79.45
%
0.89
761
7962
0
20
0.00
0.60
0.0
1.6
—
348.65
—
0
20
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
46
381
1.21
0.59
1.1
1.0
—
—
—
0
0
14
97
1.44
0.59
1.4
2.5
6.72
7.44
mmol/l
—
9
61
14
197
0.71
0.58
1.1
1.1
—
127.14
—
0
7
337
3165
1.07
0.57
3.5
3.1
4.64
4.40
kpa
0.65
327
3044
12
81
1.48
0.57
1.0
1.1
—
—
—
0
0
20
150
1.34
0.55
1.0
1.1
136.85
135.92
nmol/l
0.04
20
150
6
37
1.62
0.55
1.0
1.3
—
—
—
0
0
21
159
1.32
0.55
1.3
1.2
—
—
—
0
0
9
61
1.48
0.53
1.1
1.5
325.67
234.82
nmol/24h
—
9
61
9
64
1.41
0.51
1.1
1.1
—
—
—
0
0
86
762
1.13
0.51
1.2
1.1
—
—
—
0
0
9
65
1.39
0.50
1.3
1.7
122.40
182.11
ng/l
—
9
65
44
520
0.84
0.50
1.2
1.2
—
—
—
0
0
43
362
1.19
0.49
1.3
1.3
100533.11
200401.34
e6/l
0.47
27
258
27
334
0.81
0.48
1.9
2.1
1.63
1.47
u/field
—
8
113
44
372
1.18
0.48
2.1
2.2
648.33
660.21
ml
0.07
27
223
173
1605
1.08
0.44
2.5
2.5
21.00
21.79
au/ml
—
8
68
29
238
1.22
0.44
1.1
1.1
—
9.28
—
0
6
17
130
1.31
0.43
1.0
1.0
—
—
—
0
0
5
31
1.61
0.43
2.4
2.7
7.70
5.33
mg/l
—
5
25
6
92
0.65
0.42
1.7
1.6
—
—
—
0
0
8
57
1.40
0.42
1.1
1.1
—
—
—
0
0
18
140
1.29
0.42
1.2
1.9
—
—
—
0
0
54
472
1.15
0.41
2.1
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
2.9
—
113.91
—
0
11
8
60
1.33
0.40
1.0
1.0
—
—
—
0
0
9
67
1.34
0.38
1.2
1.0
—
—
—
0
0
12
89
1.35
0.37
1.6
1.7
—
—
—
0
0
13
98
1.33
0.37
43.1
23.8
155.08
109.62
ug/l
1.39
13
83
13
98
1.33
0.37
1.1
1.4
152.15
179.94
mmol/24h
0.77
13
98
188
1997
0.94
0.36
3.9
3.8
—
—
—
0
0
9
71
1.27
0.36
1.2
1.4
32.73
25.30
g/l
—
9
54
18
223
0.81
0.35
2.4
1.6
—
—
—
0
0
95
871
1.09
0.35
3.3
2.6
—
—
—
0
0
33
383
0.86
0.34
3.6
3.2
—
—
—
0
0
6
87
0.69
0.33
1.2
1.1
—
—
—
0
0
49
549
0.89
0.31
1.1
1.1
—
—
—
0
0
32
276
1.16
0.31
1.0
1.2
5.75
5.25
u/ml
0.06
20
119
52
580
0.90
0.31
2.3
1.7
—
—
—
0
0
7
52
1.35
0.31
1.1
1.1
—
—
—
0
0
7
56
1.25
0.29
1.0
1.3
—
—
—
0
0
55
608
0.90
0.29
2.6
2.4
—
—
—
0
0
66
602
1.10
0.29
1.1
1.1
—
—
—
0
0
45
402
1.12
0.28
1.2
1.4
120.57
141.99
u/ml
0.45
12
83
10
76
1.32
0.28
1.2
1.3
—
—
—
0
0
12
94
1.28
0.28
1.2
1.1
—
—
—
0
0
86
797
1.08
0.27
1.6
1.6
—
—
—
0
0
8
65
1.23
0.27
1.8
1.3
0.89
0.93
ug/l
—
8
59
42
469
0.89
0.27
1.6
1.6
—
—
—
0
0
8
66
1.21
0.26
1.1
1.8
—
—
—
0
0
21
178
1.18
0.26
1.3
1.2
—
—
—
0
0
41
367
1.12
0.26
1.1
1.2
357.64
293.57
u/ml
0.78
22
217
17
203
0.84
0.25
1.1
1.2
8.70
9.90
mmol/l
1.18
17
186
9
73
1.23
0.25
1.1
1.4
—
—
—
0
0
19
224
0.85
0.25
1.3
1.4
—
—
—
0
0
54
492
1.10
0.25
1.2
1.2
—
—
—
0
0
25
217
1.15
0.24
1.3
2.1
—
—
—
0
0
23
199
1.16
0.23
1.2
1.3
—
—
—
0
0
46
418
1.10
0.23
1.4
1.5
4.03
4.02
iu/l
0.00
15
109
117
1106
1.06
0.23
4.0
3.2
4.21
4.29
pmol/l
0.39
99
947
11
88
1.25
0.22
1.1
1.4
—
—
—
0
0
5
40
1.25
0.22
1.6
1.5
—
—
—
0
0
7
94
0.74
0.22
1.0
1.8
—
—
—
0
0
5
41
1.22
0.22
1.2
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.2
—
8.17
—
0
16
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
53
574
0.92
0.20
1.2
1.3
9.67
29.24
e6/l
0.86
40
453
28
249
1.13
0.20
2.5
1.7
11.75
10.74
%
0.47
28
249
53
573
0.92
0.20
1.3
1.4
255.53
893.76
e6/l
1.42
43
472
6
49
1.22
0.20
1.2
1.6
—
—
—
0
0
66
616
1.07
0.19
2.5
1.3
0.86
0.83
nmol/l
0.18
49
500
10
81
1.24
0.18
1.3
1.4
1.50
1.47
g/l
—
10
81
17
147
1.16
0.18
1.1
1.1
—
—
—
0
0
51
474
1.08
0.17
1.2
1.3
—
—
—
0
0
11
91
1.21
0.17
1.1
1.4
—
—
—
0
0
39
358
1.09
0.17
1.1
1.1
—
—
—
0
0
7
62
1.13
0.17
1.0
1.1
—
—
—
0
0
16
184
0.87
0.17
1.4
1.3
—
—
—
0
0
5
69
0.72
0.17
5.4
7.8
—
—
—
0
0
116
1211
0.96
0.16
4.0
4.4
—
—
—
0
0
18
204
0.88
0.16
5.1
3.5
—
—
—
0
0
11
92
1.20
0.16
1.1
1.4
—
—
—
0
0
30
327
0.92
0.14
1.1
1.1
—
—
—
0
0
7
89
0.79
0.14
5.9
8.5
—
—
—
0
0
738
7477
0.98
0.14
1.3
1.3
—
—
—
0
0
25
227
1.10
0.14
2.4
2.5
—
—
—
0
0
35
324
1.08
0.14
1.4
1.3
277.07
316.37
nmol/l
0.80
29
235
8
97
0.82
0.13
1.3
1.6
—
—
—
0
0
78
817
0.95
0.13
3.2
3.0
—
—
—
0
0
39
417
0.93
0.13
2.8
3.5
10.07
9.30
nmol/l
0.07
39
410
96
998
0.96
0.12
21.2
13.1
—
—
—
0
0
13
148
0.88
0.12
4.5
3.4
61.50
53.06
%
0.94
13
142
17
152
1.12
0.12
1.6
2.5
2205.83
1926.70
ml
0.55
12
119
56
533
1.05
0.11
1.4
1.3
—
—
—
0
0
11
96
1.15
0.10
2.5
1.6
37.62
55.15
ug/l
1.27
11
90
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
10
87
1.15
0.09
1.1
1.4
—
—
—
0
0
10
87
1.15
0.09
1.1
1.4
—
—
—
0
0
5
48
1.04
0.09
3.2
1.6
44.42
35.71
pmol/l
—
5
36
109
1060
1.03
0.09
3.6
3.6
—
—
—
0
0
6
56
1.07
0.08
11.5
11.7
4.08
5.37
mmol/l
—
6
56
41
390
1.05
0.08
1.2
1.3
—
—
—
0
0
5
61
0.82
0.08
1.0
1.6
2.24
1.89
umol/l
—
5
56
5
60
0.83
0.08
12.6
6.9
14.74
13.69
%
—
5
60
40
382
1.05
0.07
1.1
1.1
38.00
526.58
iu/ml
—
5
64
8
78
1.03
0.07
2.6
1.3
—
—
—
0
0
18
194
0.93
0.07
1.7
1.8
0.56
2.77
u/field
—
9
129
154
1567
0.98
0.06
1.2
1.2
—
—
—
0
0
11
99
1.11
0.06
2.2
2.7
—
—
—
0
0
68
661
1.03
0.06
1.3
1.3
—
—
—
0
0
355
3577
0.99
0.04
3.0
2.7
11.11
10.43
umol/l
0.20
313
3179
719
7160
1.01
0.03
4.6
3.7
—
—
—
0
0
1260
12635
1.00
0.03
3.6
3.4
0.77
0.84
ug/l
1.39
924
9387
19
181
1.05
0.03
1.4
1.4
135.25
149.26
pmol/l
0.25
19
181
33
320
1.03
0.03
2.1
2.0
1.47
2.15
ug/l
1.58
26
261
29
299
0.97
0.02
1.5
1.2
1.36
1.46
nmol/l
0.26
29
264
25
242
1.03
0.02
1.1
1.2
—
—
—
0
0
27
278
0.97
0.02
1.3
1.4
—
—
—
0
0
14
133
1.05
0.01
2.7
2.2
—
—
—
0
0
39
382
1.02
0.01
1.0
1.1
—
—
—
0
0
83
821
1.01
0.01
3.8
3.7
25.54
33.73
mg/l
1.24
59
548
28
273
1.03
0.01
1.3
1.2
—
—
—
0
0
27
277
0.97
0.01
1.6
1.7
—
2.00
—
0
5
18
186
0.97
0.00
1.1
1.1
—
3.30
—
0
10
13
132
0.98
0.00
3.2
2.5
—
—
—
0
0
19
185
1.03
0.00
1.1
1.0
4.86
3.00
u/ml
—
5
41
10
104
0.96
0.00
3.6
6.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
2.13
—
0
9
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
7
73
0.96
0.00
3.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
92
0.98
-0.00
1.9
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
62
0.97
-0.00
1.2
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.9
—
338.43
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
9
92
0.98
-0.00
1.0
1.2
—
0.16
—
0
5

Mortality – FinRegistry

Association

Association between endpoint J10_PLEURPLAGUE and mortality.

Females

Parameter HR [95% CI] p-value
J10_PLEURPLAGUE 1.23 [1.1, 1.37] < 0.001
Birth year 0.998 [0.99, 1.01] 0.658

During the follow-up period (1.1.1998 — 31.12.2019), 1033 out of 2963 females with J10_PLEURPLAGUE died.

Males

Parameter HR [95% CI] p-value
J10_PLEURPLAGUE 1.37 [1.26, 1.49] < 0.001
Birth year 0.985 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 7086 out of 17328 males with J10_PLEURPLAGUE died.

Mortality risk

Mortality risk for people of age

years, who have J10_PLEURPLAGUE.

N-year risk Females Males
1 0.142% 0.227%
5 0.715% 1.345%
10 1.869% 3.572%
15 3.924% 6.586%
20 7.039% 11.352%

Relationships between endpoints

Index endpoint: J10_PLEURPLAGUE – Pleural plaque

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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