This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
197 |
4. Check minimum number of eventsNone |
197 |
5. Include endpointsNone |
197 |
6. Filter based on genotype QC (FinnGen only) |
190 |
Control definitions (FinnGen only)
- Control exclude
- R18_GENERAL_SYMPTOMS_SIGNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R[5-6]
- Name in latin
- Cachexia
Similar endpoints
↥List of similar endpoints to
Cachexia
based on the number of shared cases.
Similar with more cases:
- General symptoms and signs
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 190 | 80 | 110 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | 74.10 | 71.54 | 75.96 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 197
- Matched controls
- 1970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R64
ICD-10 Finland
Cachexia
+∞
285.2
197
*
R53
ICD-10 Finland
Malaise and fatigue
5.9
27.7
63
145
R50.9
ICD-10 Finland
Fever, unspecified
10.9
26.0
30
32
R63.4
ICD-10 Finland
Abnormal weight loss
21.9
20.7
30
16
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.0
20.3
88
329
D64.9
ICD-10 Finland
Anaemia, unspecified
4.9
19.2
51
131
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.0
17.7
68
230
B03BA03
ATC
hydroxocobalamin; parenteral
5.8
14.6
29
57
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.1
13.5
88
406
Z51.5
ICD-10 Finland
Palliative care
4.4
13.0
37
99
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.4
13.0
37
99
R55
ICD-10 Finland
Syncope and collapse
11.6
11.6
21
20
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.3
10.9
51
191
JN4AD
NOMESCO Finland
Body CT examination
4.4
10.9
30
78
M05BX04
ATC
denosumab; parenteral
5.5
10.3
21
42
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
10.1
86
444
R13
ICD-10 Finland
Dysphagia
4.6
10.0
25
60
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.6
9.8
36
115
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
5.3
9.5
20
41
T08
ICPC
Weight loss
16.6
9.2
14
9
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
8.9
102
597
JN4BD
NOMESCO Finland
Extensive body CT
3.5
8.6
32
103
R18
ICD-10 Finland
Ascites
13.6
8.5
14
11
R4190
NOMESCO Finland
Nutritional therapy
10.1
8.5
16
17
M81.9
ICD-10 Finland
Osteoporosis, unspecified
7.1
8.4
20
31
A04AA01
ATC
ondansetron; systemic, rectal
4.3
8.4
23
59
AA1AD
NOMESCO Finland
CT of head and brain
2.6
8.2
61
289
N02AA05
ATC
oxycodone; systemic
2.8
8.2
50
215
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
7.7
32
110
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
19.3
7.7
11
6
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
83.1
7.5
8
*
E86
ICD-10 Finland
Volume depletion
8.9
7.5
15
18
A28
ICPC
Limited function/disability NOS
2.6
7.4
53
246
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.7
7.2
44
188
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.8
7.1
23
67
R03BB04
ATC
tiotropium bromide; inhalant
2.9
7.0
37
146
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
6.9
36
141
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
6.7
30
108
R56.8
ICD-10 Finland
Other and unspecified convulsions
72.1
6.5
7
*
R63.0
ICD-10 Finland
Anorexia
72.1
6.5
7
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.7
6.4
37
153
R52.9
ICD-10 Finland
Pain, unspecified
3.7
6.3
21
62
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
18.8
6.3
9
5
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.2
6.3
17
43
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
27.6
6.3
8
*
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
27.6
6.3
8
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.7
6.2
20
58
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.6
6.2
39
169
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.3
6.0
16
40
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
62
155
5.38
24.60
6.0
5.5
1.02
1.01
mmol/l
0.08
56
142
95
339
4.48
24.05
2.6
1.9
2.85
3.07
mg/l
0.47
81
291
118
577
3.61
17.46
8.1
4.1
31.17
35.22
g/l
7.25
110
527
24
34
7.90
16.49
1.7
1.2
278.87
320.42
ug/g
0.31
17
13
118
614
3.30
15.08
10.6
4.8
1.20
1.21
mmol/l
1.13
109
537
124
668
3.31
14.87
9.8
5.6
1.20
1.21
mmol/l
1.17
95
558
23
35
7.31
14.82
2.9
3.0
30.18
36.96
mg/l
0.52
16
29
23
35
7.31
14.82
3.0
3.0
47.04
235.67
mg/l
0.55
17
29
123
667
3.25
14.45
12.7
15.7
1.26
1.40
inr
0.86
34
172
108
546
3.16
14.28
3.4
2.5
225.39
142.00
ug/l
2.15
99
486
80
341
3.27
14.16
1.9
1.5
19.69
20.28
nmol/l
0.12
71
276
44
135
3.91
12.84
2.5
2.4
6.28
10.08
umol/l
0.96
38
115
22
39
6.22
12.25
2.0
1.6
1.78
0.52
ug/l
1.03
22
32
67
287
3.02
11.40
2.5
1.7
1304.16
1234.33
nmol/l
0.21
49
210
52
197
3.23
10.87
2.4
1.6
—
—
—
0
0
21
40
5.76
10.85
4.0
2.2
—
—
—
0
0
76
360
2.81
10.64
2.6
1.8
120.94
408.06
u/l
2.15
70
331
28
71
4.43
10.45
5.4
5.5
24.73
24.23
mmol/l
0.17
28
71
28
72
4.37
10.26
1.7
1.4
—
—
—
0
0
99
548
2.62
10.04
5.9
3.5
60.91
46.80
ng/l
0.46
85
411
32
96
3.79
9.52
2.1
1.4
—
—
—
0
0
41
150
3.19
8.97
7.9
6.2
0.88
1.07
mmol/l
0.06
27
122
87
472
2.51
8.96
3.9
3.1
—
—
—
0
0
28
81
3.86
8.74
5.2
4.7
3.86
1.78
mmol/l
1.98
23
60
117
733
2.47
8.71
13.2
7.2
5.08
4.21
e9/l
1.55
108
636
72
363
2.55
8.60
3.2
3.2
1.02
0.42
e6/l
0.75
62
273
98
582
2.36
8.04
2.5
2.0
82.24
93.81
pmol/l
1.62
57
299
22
57
4.22
7.94
5.2
3.9
23.76
23.62
mmol/l
0.05
22
57
29
96
3.37
7.40
1.8
1.6
1.88
1.59
%
0.66
23
86
35
131
3.03
7.31
2.6
1.7
—
—
—
0
0
17
26
7.05
7.29
2.0
1.5
—
—
—
0
0
32
114
3.16
7.26
4.9
3.7
4.15
1.31
mmol/l
1.91
24
96
28
92
3.38
7.23
5.3
4.3
5.38
5.16
kpa
0.62
28
87
90
536
2.25
7.11
3.5
2.2
79.34
79.12
nmol/l
0.02
78
457
18
31
6.28
7.11
1.3
1.1
—
—
—
0
0
130
904
2.29
6.96
6.4
4.1
14.60
990.48
e6/l
—
5
25
34
131
2.93
6.73
2.6
1.6
—
—
—
0
0
18
47
4.11
6.42
2.1
1.4
—
—
—
0
0
77
453
2.15
6.07
3.8
3.0
2.32
2.35
mmol/l
0.94
66
393
13
18
7.65
6.03
3.1
3.2
57.38
57.00
%
0.03
13
18
77
455
2.14
5.99
3.2
3.0
5392.62
1907.53
ng/l
1.48
66
388
38
166
2.60
5.91
8.9
5.8
104.45
104.72
mmol/l
0.11
38
166
16
31
5.52
5.85
1.8
1.5
—
—
—
0
0
12
17
7.44
5.53
3.4
3.3
4.75
3.92
e9/l
0.59
12
17
108
739
2.02
5.52
4.7
2.6
66.68
46.06
u/l
1.20
101
677
44
215
2.35
5.37
2.4
1.7
29.37
29.18
s
0.10
44
207
14
28
5.30
5.05
7.6
3.4
5.01
5.15
kpa
0.18
14
28
10
13
8.03
4.91
1.2
1.5
—
—
—
0
0
11
19
6.06
4.51
1.6
1.2
—
—
—
0
0
41
213
2.17
4.28
2.3
2.8
1.26
0.93
e6/l
0.31
28
119
21
80
2.82
4.22
2.3
1.6
—
—
—
0
0
11
21
5.48
4.21
1.6
1.1
—
—
—
0
0
14
42
3.51
4.13
1.2
1.6
0.00
1.11
g/l
—
9
36
127
977
1.84
4.03
5.3
3.6
20.58
12.82
mm/h
4.72
120
888
9
14
6.68
4.03
1.3
1.2
—
—
—
0
0
9
14
6.68
4.03
1.3
1.2
—
—
—
0
0
9
14
6.68
4.03
1.4
1.1
—
—
—
0
0
42
228
2.07
3.90
1.5
1.2
0.91
0.89
u/ml
0.04
14
51
30
142
2.31
3.90
5.5
3.0
—
—
—
0
0
8
11
7.52
3.90
1.9
1.1
—
—
—
0
0
16
55
3.08
3.83
5.8
5.3
26.39
25.45
mmol/l
0.55
16
50
33
165
2.20
3.77
3.8
4.6
960.89
10.53
ug/l
0.50
28
139
11
25
4.60
3.68
5.0
2.1
14.02
16.28
%
—
5
14
28
133
2.29
3.61
2.1
2.2
4.32
8.05
ug/l
1.89
23
113
8
13
6.36
3.53
1.4
1.1
—
—
—
0
0
43
244
1.98
3.53
4.6
3.0
574.23
334.05
ng/l
0.28
35
210
59
372
1.84
3.52
5.8
3.8
0.00
0.00
estimate
-0.00
23
112
86
614
1.71
3.32
3.7
2.7
—
—
—
0
0
13
39
3.49
3.29
5.5
2.8
26.02
25.15
mmol/l
0.28
13
39
6
8
7.69
3.07
1.2
1.1
—
—
—
0
0
6
8
7.69
3.07
1.2
1.1
—
—
—
0
0
6
8
7.69
3.07
1.8
1.0
—
—
—
0
0
6
9
6.83
2.89
1.7
1.1
—
—
—
0
0
36
206
1.91
2.87
3.1
2.9
1.89
1.72
e6/l
0.08
23
112
122
979
1.65
2.86
4.3
3.4
15.07
15.03
pmol/l
0.05
108
847
10
29
3.58
2.73
1.6
1.4
—
—
—
0
0
87
648
1.61
2.72
5.4
3.5
0.00
0.00
estimate
-0.00
24
126
7
15
4.80
2.62
1.3
1.3
3.69
3.72
mmol/l
—
7
15
6
11
5.59
2.56
1.7
1.0
—
—
—
0
0
50
329
1.70
2.51
3.1
2.4
—
—
—
0
0
8
21
3.92
2.49
1.9
1.2
100.38
331.15
u/l
—
8
21
44
282
1.72
2.43
5.3
2.8
2.47
2.46
mmol/l
0.29
38
240
47
307
1.70
2.42
2.3
1.9
478.73
22530079.95
pmol/l
0.50
40
253
5
8
6.38
2.38
1.6
1.4
—
—
—
0
0
5
8
6.38
2.38
1.6
1.4
—
—
—
0
0
7
17
4.23
2.38
1.3
1.3
415.14
628.94
mg/l
—
7
17
14
59
2.48
2.35
1.5
1.6
—
—
—
0
0
86
659
1.54
2.29
5.4
3.5
0.00
0.00
estimate
-0.00
24
108
85
652
1.53
2.24
6.7
4.5
0.00
0.00
estimate
-0.00
24
112
5
9
5.67
2.22
1.4
1.1
—
—
—
0
0
5
9
5.67
2.22
1.4
1.1
—
—
—
0
0
5
9
5.67
2.22
1.4
1.1
—
—
—
0
0
5
9
5.67
2.22
1.4
1.1
—
—
—
0
0
5
9
5.67
2.22
1.0
1.2
—
—
—
0
0
7
19
3.78
2.17
1.4
1.3
27.43
12.89
u/l
—
7
19
6
14
4.38
2.16
1.7
1.1
—
—
—
0
0
40
259
1.68
2.12
1.5
1.5
1.68
1.30
mg/l
0.53
35
204
152
1334
1.61
2.08
34.6
12.5
30.06
27.34
mg/l
0.53
140
1040
5
10
5.10
2.08
1.6
1.2
—
—
—
0
0
5
10
5.10
2.08
1.4
1.1
—
—
—
0
0
5
10
5.10
2.08
1.6
1.2
—
—
—
0
0
5
10
5.10
2.08
1.4
1.1
—
—
—
0
0
5
10
5.10
2.08
1.6
1.2
—
—
—
0
0
6
15
4.09
2.05
4.3
1.5
—
—
—
0
0
6
17
3.61
1.85
1.0
1.2
—
—
—
0
0
6
17
3.61
1.85
1.8
1.6
9.67
11.65
u/l
—
6
17
12
53
2.35
1.84
1.2
1.6
—
—
—
0
0
13
60
2.25
1.82
1.3
1.1
690.42
90.01
u/ml
0.74
13
55
67
509
1.48
1.77
6.1
3.6
—
—
—
0
0
21
347
0.56
1.76
1.5
1.6
0.99
1.30
mmol/l
2.26
14
282
6
18
3.40
1.76
1.2
1.5
—
—
—
0
0
8
30
2.74
1.74
1.0
1.3
—
—
—
0
0
6
20
3.06
1.59
1.3
1.2
—
—
—
0
0
6
20
3.06
1.59
1.2
1.2
—
—
—
0
0
6
21
2.91
1.51
1.2
1.1
—
—
—
0
0
120
1349
0.72
1.43
4.2
5.2
2.18
2.60
mmol/l
6.05
110
1222
6
23
2.66
1.38
1.0
1.6
—
—
—
0
0
6
23
2.66
1.38
1.0
1.6
—
—
—
0
0
13
68
1.98
1.37
1.0
1.2
195.60
126.73
iu/ml
—
5
21
117
1312
0.73
1.30
4.0
4.5
4.19
4.49
mmol/l
2.37
108
1195
77
631
1.36
1.27
3.0
2.5
—
—
—
0
0
18
109
1.72
1.24
3.2
2.5
607.58
173.93
ng/l
1.27
18
100
116
1298
0.74
1.23
4.0
4.5
1.54
1.46
mmol/l
0.81
107
1164
5
19
2.67
1.22
2.2
3.7
—
—
—
0
0
21
313
0.63
1.18
3.0
3.2
0.65
0.81
ug/l
0.83
16
211
153
1404
1.40
1.16
38.6
16.0
138.05
139.82
mmol/l
9.17
147
1356
135
1216
1.35
1.15
5.4
4.3
2.16
2.02
mu/l
0.25
121
1065
153
1407
1.39
1.12
38.8
16.1
4.01
4.00
mmol/l
0.13
147
1358
7
32
2.23
1.09
1.9
1.9
—
—
—
0
0
6
29
2.10
0.90
1.7
1.2
—
—
—
0
0
43
341
1.33
0.86
3.1
2.5
6880.29
8376.68
umol/l
0.08
38
287
115
1257
0.80
0.82
3.8
4.0
1.07
1.24
mmol/l
2.85
104
1121
6
34
1.79
0.77
2.8
2.0
—
—
—
0
0
36
444
0.77
0.70
4.4
4.6
20.37
21.52
%
0.17
19
226
5
27
1.87
0.69
1.6
1.7
97.00
80.81
%
—
5
27
117
1264
0.82
0.68
5.2
6.1
38.58
40.58
mmol/mol
1.12
104
1164
136
1268
1.23
0.66
31.8
12.8
73.94
73.53
ml/min/173m2
0.07
125
1015
156
1479
1.26
0.63
47.2
19.8
257.68
241.41
e9/l
1.79
151
1435
8
50
1.62
0.62
1.5
1.9
39.13
41.69
u/l
—
8
43
156
1481
1.26
0.61
47.4
19.9
36.22
39.68
%
10.42
144
1368
156
1481
1.26
0.61
47.2
19.8
3.93
4.46
e12/l
21.88
151
1427
156
1482
1.25
0.60
47.7
19.9
119.19
134.19
g/l
22.12
151
1447
6
37
1.64
0.56
1.0
1.1
—
—
—
0
0
6
38
1.60
0.55
1.0
1.1
—
—
—
0
0
5
32
1.58
0.42
1.0
1.2
—
—
—
0
0
18
142
1.29
0.40
1.2
1.5
—
—
—
0
0
8
61
1.32
0.40
3.9
3.7
34.75
4379.96
u/ml
—
8
56
5
36
1.40
0.38
2.2
1.5
—
—
—
0
0
9
70
1.30
0.37
1.6
1.8
—
—
—
0
0
10
75
1.35
0.31
1.6
1.8
—
—
—
0
0
13
104
1.27
0.27
1.8
3.2
66.86
59.86
ml/min/173m2
—
7
42
5
73
0.68
0.26
1.2
1.8
—
—
—
0
0
42
463
0.88
0.26
3.7
3.8
36.26
10.01
mg/mmol
0.94
27
293
0
10
0.00
0.21
0.0
2.3
—
7.24
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
1.50
—
0
6
54
563
0.94
0.10
4.6
5.5
1.68
3.13
ug/l
1.63
49
489
6
57
1.05
0.08
1.0
1.3
—
—
—
0
0
20
188
1.07
0.06
1.2
1.2
49.10
11.64
u/ml
—
6
73
16
152
1.06
0.02
1.4
1.4
—
—
—
0
0
17
176
0.96
0.00
11.9
7.2
—
—
—
0
0
21
204
1.03
0.00
1.3
1.2
40.57
40.04
iu/ml
—
7
68
132
1322
1.00
0.00
4.4
4.9
6.03
6.04
mmol/l
0.02
118
1184
0
6
0.00
0.00
0.0
3.0
—
71.83
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
67
0.89
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_CACHEXIA – Cachexia
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).