This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
180 |
4. Check minimum number of eventsNone |
180 |
5. Include endpointsNone |
180 |
6. Filter based on genotype QC (FinnGen only) |
180 |
Control definitions (FinnGen only)
- Control exclude
- R18_GENERAL_SYMPTOMS_SIGNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R[5-6]
- Name in latin
- Cachexia
Similar endpoints
↥List of similar endpoints to
Cachexia
based on the number of shared cases.
Similar with more cases:
- General symptoms and signs
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 180 | 74 | 106 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | 72.18 | 67.87 | 75.20 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 158
- Matched controls
- 1578
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R64
ICD-10 Finland
Cachexia
+∞
228.4
158
*
R63.4
ICD-10 Finland
Abnormal weight loss
42.2
18.1
22
6
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.4
15.1
69
238
R53
ICD-10 Finland
Malaise and fatigue
5.8
14.4
44
98
D64.9
ICD-10 Finland
Anaemia, unspecified
5.0
11.0
37
90
R50.9
ICD-10 Finland
Fever, unspecified
7.9
10.6
24
35
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.1
10.1
43
132
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.2
10.0
65
281
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.1
9.2
38
113
B03BA03
ATC
hydroxocobalamin; parenteral
6.0
9.1
25
48
R55
ICD-10 Finland
Syncope and collapse
11.7
9.0
16
15
Z51.5
ICD-10 Finland
Palliative care
5.3
8.8
27
59
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
8.6
65
302
E86
ICD-10 Finland
Volume depletion
16.1
7.8
12
8
R18
ICD-10 Finland
Ascites
19.5
7.7
11
6
N02AA05
ATC
oxycodone; systemic
3.6
7.7
36
119
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
6.2
7.7
20
36
R03BB04
ATC
tiotropium bromide; inhalant
3.9
7.6
32
97
R63.0
ICD-10 Finland
Anorexia
+∞
7.3
7
*
R13
ICD-10 Finland
Dysphagia
5.8
7.0
19
36
A28
ICPC
Limited function/disability NOS
3.2
6.9
39
148
A04AA01
ATC
ondansetron; systemic, rectal
6.7
6.7
16
26
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.2
6.5
36
134
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
72.6
6.5
7
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
9.2
6.2
12
14
JN4BD
NOMESCO Finland
Extensive body CT
4.0
6.0
23
64
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_CACHEXIA – Cachexia
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).