This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
180 |
4. Check minimum number of eventsNone |
180 |
5. Include endpointsNone |
180 |
6. Filter based on genotype QC (FinnGen only) |
180 |
Control definitions (FinnGen only)
- Control exclude
- R18_GENERAL_SYMPTOMS_SIGNS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R[5-6]
- Name in latin
- Cachexia
Similar endpoints
↥List of similar endpoints to
Cachexia
based on the number of shared cases.
Similar with more cases:
- General symptoms and signs
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 180 | 74 | 106 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | 72.18 | 67.87 | 75.20 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 158
- Matched controls
- 1578
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R64
ICD-10 Finland
Cachexia
+∞
228.4
158
*
R63.4
ICD-10 Finland
Abnormal weight loss
42.2
18.1
22
6
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.4
15.1
69
238
R53
ICD-10 Finland
Malaise and fatigue
5.8
14.4
44
98
D64.9
ICD-10 Finland
Anaemia, unspecified
5.0
11.0
37
90
R50.9
ICD-10 Finland
Fever, unspecified
7.9
10.6
24
35
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.1
10.1
43
132
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.2
10.0
65
281
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.1
9.2
38
113
B03BA03
ATC
hydroxocobalamin; parenteral
6.0
9.1
25
48
R55
ICD-10 Finland
Syncope and collapse
11.7
9.0
16
15
Z51.5
ICD-10 Finland
Palliative care
5.3
8.8
27
59
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
8.6
65
302
E86
ICD-10 Finland
Volume depletion
16.1
7.8
12
8
R18
ICD-10 Finland
Ascites
19.5
7.7
11
6
N02AA05
ATC
oxycodone; systemic
3.6
7.7
36
119
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
6.2
7.7
20
36
R03BB04
ATC
tiotropium bromide; inhalant
3.9
7.6
32
97
R63.0
ICD-10 Finland
Anorexia
+∞
7.3
7
*
R13
ICD-10 Finland
Dysphagia
5.8
7.0
19
36
A28
ICPC
Limited function/disability NOS
3.2
6.9
39
148
A04AA01
ATC
ondansetron; systemic, rectal
6.7
6.7
16
26
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.2
6.5
36
134
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
72.6
6.5
7
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
9.2
6.2
12
14
JN4BD
NOMESCO Finland
Extensive body CT
4.0
6.0
23
64
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
83
303
4.23
20.08
2.6
1.9
2.9
3.1
mg/l
0.37
72
258
54
149
4.75
18.77
6.0
5.9
1.0
1.0
mmol/l
0.01
48
137
105
513
3.51
15.45
8.2
4.3
31.0
35.2
g/l
7.13
98
468
21
28
8.36
15.17
1.6
1.2
281.3
321.3
ug/g
0.28
15
13
104
550
3.11
12.61
10.8
4.7
1.2
1.2
mmol/l
0.90
96
479
41
123
4.02
12.41
2.4
2.4
6.2
10.3
umol/l
0.95
35
105
109
600
3.07
12.16
10.0
5.5
1.2
1.2
mmol/l
1.31
82
500
20
33
6.69
11.94
2.9
2.2
30.9
37.1
mg/l
0.42
13
28
20
33
6.69
11.94
3.0
2.2
48.9
242.0
mg/l
0.54
14
28
22
41
5.97
11.67
2.0
1.6
1.8
0.6
ug/l
0.94
22
33
69
305
3.05
11.25
1.8
1.5
20.0
20.2
nmol/l
0.05
63
247
95
500
2.91
11.25
3.4
2.5
236.8
138.1
ug/l
2.40
87
447
17
25
7.40
11.22
2.0
1.4
—
—
—
0
0
19
35
5.95
10.16
4.3
1.8
—
—
—
0
0
46
183
3.03
8.79
2.4
1.6
—
—
—
0
0
28
81
3.91
8.78
2.2
1.5
—
—
—
0
0
12
16
7.96
8.51
3.1
3.4
57.3
57.9
%
0.04
12
16
57
260
2.74
8.44
2.6
1.8
1292.2
1232.8
nmol/l
0.16
42
193
24
67
3.98
7.88
1.8
1.4
—
—
—
0
0
65
330
2.52
7.65
2.8
1.9
125.2
371.7
u/l
1.95
59
306
11
15
7.75
7.64
3.4
3.5
4.9
4.1
e9/l
0.52
11
15
36
138
3.01
7.26
8.4
5.8
1.3
1.1
mmol/l
0.06
24
114
85
500
2.33
7.09
6.0
3.6
64.9
49.4
ng/l
0.44
72
377
11
17
6.83
6.86
1.6
1.1
—
—
—
0
0
15
32
5.02
6.82
1.3
1.1
—
—
—
0
0
26
86
3.36
6.66
1.9
1.7
1.9
1.6
%
0.66
21
77
14
29
5.15
6.57
1.8
1.5
—
—
—
0
0
85
514
2.24
6.50
2.5
2.0
82.3
92.7
pmol/l
1.20
50
267
102
666
2.23
6.43
13.5
7.0
4.9
4.3
e9/l
1.22
95
573
11
19
6.10
6.18
1.6
1.1
—
—
—
0
0
79
474
2.19
6.06
3.3
2.3
79.0
78.2
nmol/l
0.07
70
407
25
86
3.21
6.01
5.7
3.6
5.4
5.2
kpa
0.65
25
72
28
105
2.97
5.83
5.5
4.0
4.6
1.4
mmol/l
1.82
20
85
74
441
2.15
5.70
3.8
3.1
—
—
—
0
0
115
815
2.14
5.57
6.3
4.1
14.6
3007.0
e6/l
—
5
24
16
43
3.99
5.50
2.2
1.5
4.0
3.8
g/l
—
8
30
16
43
3.99
5.50
2.2
1.5
7.3
7.6
g/l
—
8
32
16
43
3.99
5.50
2.2
1.5
—
—
—
0
0
30
122
2.75
5.38
2.7
1.6
—
—
—
0
0
98
670
2.02
5.05
4.8
2.7
67.1
45.0
u/l
1.19
91
621
15
41
3.90
5.04
2.3
1.5
3.1
3.3
g/l
—
8
31
40
194
2.37
4.99
2.5
1.7
29.7
29.3
s
0.26
40
186
29
124
2.60
4.71
2.7
1.6
—
—
—
0
0
14
39
3.81
4.58
1.4
1.6
9.3
11.1
g/l
—
9
33
58
339
2.05
4.54
3.2
3.1
1.2
0.5
e6/l
0.68
50
253
67
417
1.97
4.37
3.1
3.0
5634.5
1944.2
ng/l
1.30
57
352
8
9
9.23
4.32
1.9
1.0
—
—
—
0
0
9
13
7.22
4.21
1.4
1.1
—
—
—
0
0
31
146
2.36
4.10
3.6
4.3
1034.7
10.6
ug/l
0.50
26
122
34
176
2.15
3.60
17.2
26.8
1.9
1.5
inr
—
5
22
8
13
6.38
3.54
1.3
1.4
—
—
—
0
0
10
27
3.86
3.40
1.6
1.6
—
—
—
0
0
62
407
1.80
3.28
3.9
3.0
2.3
2.4
mmol/l
0.94
52
354
37
206
2.00
3.22
1.5
1.2
1.0
0.9
u/ml
0.12
11
47
6
8
7.71
3.08
1.8
1.0
—
—
—
0
0
6
8
7.71
3.08
1.7
1.1
—
—
—
0
0
14
51
2.89
3.06
1.5
1.6
—
—
—
0
0
39
226
1.93
3.03
4.7
3.1
625.8
266.5
ng/l
0.42
32
193
5
5
10.23
2.99
1.6
1.4
—
—
—
0
0
5
5
10.23
2.99
1.6
1.4
—
—
—
0
0
8
17
4.87
2.95
1.9
1.3
100.4
287.7
u/l
—
8
17
27
139
2.11
2.89
5.3
3.1
—
—
—
0
0
6
9
6.85
2.89
1.2
1.1
—
—
—
0
0
77
555
1.68
2.85
7.1
4.1
—
—
—
0
0
18
78
2.45
2.85
2.2
1.6
—
—
—
0
0
6
10
6.16
2.72
1.7
1.0
—
—
—
0
0
110
883
1.63
2.58
5.5
3.6
21.5
13.0
mm/h
4.61
103
803
5
7
7.30
2.56
1.6
1.1
—
—
—
0
0
5
7
7.30
2.56
1.6
1.1
—
—
—
0
0
5
7
7.30
2.56
1.6
1.1
—
—
—
0
0
16
323
0.45
2.53
1.7
1.5
1.0
1.3
mmol/l
1.49
11
258
7
16
4.51
2.50
1.4
1.4
27.4
11.0
u/l
—
7
16
11
40
2.86
2.42
6.1
2.9
26.4
25.3
mmol/l
0.27
11
29
5
8
6.39
2.38
1.4
1.1
—
—
—
0
0
5
8
6.39
2.38
1.4
1.1
—
—
—
0
0
5
8
6.39
2.38
1.0
1.3
—
—
—
0
0
5
8
6.39
2.38
1.4
1.1
—
—
—
0
0
5
8
6.39
2.38
1.4
1.1
—
—
—
0
0
12
47
2.66
2.32
1.2
1.6
—
—
—
0
0
6
13
4.73
2.29
1.7
1.1
—
—
—
0
0
44
288
1.70
2.27
3.3
2.4
—
—
—
0
0
5
9
5.68
2.23
1.4
1.1
—
—
—
0
0
5
9
5.68
2.23
1.4
1.1
—
—
—
0
0
6
14
4.39
2.17
1.8
1.7
9.7
12.2
u/l
—
6
14
32
195
1.78
2.11
2.8
2.9
1.9
1.3
e6/l
0.38
22
106
7
21
3.42
1.98
2.0
1.2
5129.6
35847.2
e6/l
—
7
16
104
1214
0.66
1.95
4.0
5.2
2.2
2.6
mmol/l
5.03
94
1098
41
275
1.64
1.92
2.3
1.9
482.8
25676108.4
pmol/l
0.50
35
222
106
879
1.50
1.90
3.9
3.5
14.9
15.0
pmol/l
0.15
94
762
32
203
1.70
1.85
2.1
2.8
0.7
0.9
e6/l
0.33
22
114
6
18
3.41
1.76
1.3
1.2
—
—
—
0
0
6
18
3.41
1.76
1.2
1.4
—
—
—
0
0
102
1185
0.68
1.76
3.8
4.6
4.2
4.5
mmol/l
2.63
93
1081
49
352
1.54
1.72
5.6
3.8
0.0
0.0
estimate
0.00
21
105
101
1172
0.69
1.69
3.8
4.5
1.5
1.5
mmol/l
0.51
92
1051
6
20
3.07
1.59
1.2
1.2
—
—
—
0
0
5
17
2.99
1.37
1.0
1.6
—
—
—
0
0
5
17
2.99
1.37
1.0
1.6
—
—
—
0
0
74
601
1.39
1.34
5.0
3.4
0.0
0.0
estimate
0.00
22
110
135
1214
1.45
1.33
35.6
12.6
31.2
26.8
mg/l
0.95
124
948
29
411
0.65
1.32
3.9
4.5
21.5
21.8
%
0.04
17
210
5
18
2.83
1.29
1.2
1.1
—
—
—
0
0
100
1136
0.73
1.26
3.6
4.1
1.1
1.2
mmol/l
2.39
89
1014
100
1136
0.73
1.26
4.9
6.3
38.4
40.7
mmol/mol
1.15
89
1047
16
97
1.71
1.11
3.5
2.7
664.7
164.4
ng/l
1.33
16
88
11
60
1.89
1.05
1.0
1.2
195.6
109.9
iu/ml
—
5
19
73
614
1.32
1.00
5.1
3.4
0.0
0.0
estimate
0.00
22
101
72
606
1.31
0.98
6.1
4.5
0.0
0.0
estimate
0.00
22
107
6
27
2.26
0.94
2.3
2.0
—
—
—
0
0
6
28
2.18
0.92
1.0
1.3
—
—
—
0
0
8
43
1.90
0.88
1.5
1.9
39.1
40.6
u/l
—
8
37
136
1260
1.32
0.85
38.8
16.1
138.0
139.8
mmol/l
8.65
130
1214
136
1263
1.31
0.81
38.9
16.3
4.0
4.0
mmol/l
0.05
130
1217
118
1086
1.25
0.70
4.9
4.3
2.0
2.0
mu/l
0.05
107
947
5
27
1.88
0.69
1.8
1.1
—
—
—
0
0
56
477
1.25
0.67
5.6
3.6
—
—
—
0
0
5
28
1.81
0.66
1.0
1.2
—
—
—
0
0
18
130
1.43
0.64
1.2
1.5
—
—
—
0
0
5
30
1.69
0.62
3.2
2.0
—
—
—
0
0
68
599
1.22
0.59
3.0
2.6
—
—
—
0
0
11
159
0.67
0.57
12.8
7.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
6.6
—
0
15
139
1333
1.19
0.40
47.2
19.9
3.9
4.5
e12/l
21.24
134
1284
139
1334
1.18
0.39
47.7
20.0
118.5
134.2
g/l
21.49
134
1301
9
68
1.34
0.38
1.6
1.7
—
—
—
0
0
110
1041
1.15
0.36
29.2
15.2
36.2
38.9
%
2.04
68
699
10
73
1.39
0.35
1.6
1.8
—
—
—
0
0
47
523
0.86
0.34
3.8
5.5
1.8
3.2
ug/l
1.29
42
450
119
1145
1.12
0.25
31.9
13.1
74.7
73.3
ml/min/173m2
0.26
109
920
5
39
1.29
0.23
2.2
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
1.2
—
0
5
115
1182
0.93
0.16
4.0
4.9
6.0
6.1
mmol/l
0.14
102
1055
19
169
1.14
0.15
1.2
1.2
49.1
12.4
u/ml
—
6
68
11
93
1.19
0.15
1.7
3.5
55.0
57.8
ml/min/173m2
—
5
41
20
180
1.13
0.14
1.4
1.2
40.6
44.3
iu/ml
—
7
67
14
144
0.97
0.00
1.5
1.4
—
—
—
0
0
16
162
0.99
0.00
3.5
4.8
40.6
31.8
%
1.83
11
107
0
6
0.00
0.00
0.0
3.0
—
71.8
—
0
6
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_CACHEXIA – Cachexia
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).