Anogenital herpesviral [herpes simplex] infection

AB1_ANOGENITAL_HERPES_SIMPLEX

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A60
  • Hospital discharge: ICD-9 0541A
  • Hospital discharge: ICD-8 5402
  • Cause of death: ICD-10 A60
  • Cause of death: ICD-9 0541A
  • Cause of death: ICD-8 5402

2 out of 7 registries used, show all original rules.

2630

4. Check minimum number of events

None

2630

5. Include endpoints

None

2630

6. Filter based on genotype QC (FinnGen only)

2630

Control definitions (FinnGen only)

Control exclude
AB1_SEXUAL_TRANSMISSION

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17791 11901 5755
Only index persons 17294 11677 5617
Unadjusted period prevalence (%)
Whole population 0.28 0.34 0.16
Only index persons 0.36 0.43 0.21
Median age at first event (years)
Whole population 29.31 27.62 32.76
Only index persons 29.21 27.59 32.58

-FinnGen-

Key figures

All Female Male
Number of individuals 2630 1996 634
Unadjusted period prevalence (%) 0.58 0.68 0.28
Median age at first event (years) 32.68 30.00 41.09

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2351
Matched controls
23511
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J05AB11
ATC
valaciclovir; oral
14.4
323.0
1179
1539
J05AB01
ATC
aciclovir; systemic
14.1
323.0
1594
3053
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
541.4
323.0
1751
126
N77.1*A60.0
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in herpesviral [herpes simplex] infection
251.5
323.0
380
18
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
10.5
323.0
792
1086
A63.0
ICD-10 Finland
Anogenital (venereal) warts
24.2
210.1
305
144
N77.0*A60.0
ICD-10 Finland
Ulceration of vulva in herpesviral [herpes simplex] infection
110.1
151.2
164
16
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
23.9
131.2
190
86
D06BB03
ATC
aciclovir; topical
7.4
120.9
308
470
0541A
ICD-9 Finland
Herpes simplex, Genital herpes[HERPES GENITALIS PRIMARIUS]
+∞
89.1
85
*
N51.8*A60.0
ICD-10 Finland
Herpes simplex infection of the genitals in men
111.2
88.6
96
9
A60.9
ICD-10 Finland
Anogenital herpesviral infection, unspecified
70.5
83.0
95
14
J02AC01
ATC
fluconazole; systemic
2.3
78.5
1264
7944
N76.0
ICD-10 Finland
Acute vaginitis
3.2
56.9
338
1180
X90
ICPC
Genital herpes female
20.7
54.7
82
41
O98.3
ICD-10 Finland
Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium
132.9
49.0
52
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.1
47.5
641
3499
N76.8
ICD-10 Finland
Other specified inflammation of vagina and vulva
6.7
44.7
117
181
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
43.1
744
4455
D06BB04
ATC
podophyllotoxin; topical
3.2
42.9
246
831
P01AB01
ATC
metronidazole; oral, rectal
1.8
40.9
989
6658
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
39.0
894
5882
N77.1
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
6.6
37.9
100
157
X23
ICPC
Fear sexually transm dis female
2.6
35.8
286
1190
R4110
NOMESCO Finland
Physiotherapy
2.0
34.6
549
3139
J01DB01
ATC
cefalexin; oral
1.9
31.5
1945
16875
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
2.2
31.2
375
1905
ULA02
NOMESCO Finland
Kolposcopy
2.2
31.1
338
1641
Z71.8
ICD-10 Finland
Other specified counselling
1.8
30.4
654
4133
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
29.9
912
6410
N05BA04
ATC
oxazepam; oral
1.8
29.8
595
3662
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.6
29.2
230
943
B00.9
ICD-10 Finland
Herpesviral infection, unspecified
12.3
28.8
52
43
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
12.3
28.8
52
43
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
104.7
28.7
31
*
J01FA10
ATC
azithromycin; systemic
1.6
28.3
1481
11983
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
28.3
1288
10043
J01CA08
ATC
pivmecillinam; oral
1.6
28.2
1035
7620
A60.1
ICD-10 Finland
Herpesviral infection of perianal skin and rectum
55.7
28.2
33
6
J01MA02
ATC
ciprofloxacin; systemic
1.7
27.9
754
5088
N06AB04
ATC
citalopram; systemic
1.9
27.8
513
3066
N02AX02
ATC
tramadol; systemic, rectal
1.7
27.8
790
5407
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
27.6
498
2949
M79.6
ICD-10 Finland
Pain in limb
1.7
27.2
764
5203
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
26.7
275
1296
N06AX11
ATC
mirtazapine; oral
1.7
26.7
706
4721
QXA50
NOMESCO Finland
Skin cryotherapy, unspecified location
19.4
26.5
40
21
B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
4.4
26.5
98
229
R74
ICPC
Upper respiratory infection acute
1.6
25.9
887
6363
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
25.4
408
2313
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.0
25.3
375
2063
J05AB09
ATC
famciclovir; oral
12.8
24.9
44
35
A02BC02
ATC
pantoprazole; systemic
1.6
24.5
1280
10167
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
24.4
710
4852
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
2.0
23.2
314
1659
J01MA06
ATC
norfloxacin; oral
2.1
23.1
297
1539
N77.1*B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
3.9
22.8
97
259
J01AA02
ATC
doxycycline; systemic
1.6
22.5
1639
13949
M03BX02
ATC
tizanidine; oral
1.5
22.4
1421
11692
J01EA01
ATC
trimethoprim; systemic
1.7
22.1
562
3677
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
21.8
979
7418
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
4.6
21.8
77
173
J01MA12
ATC
levofloxacin; systemic
2.0
21.7
324
1778
N05CF02
ATC
zolpidem; oral
1.8
21.5
404
2405
Y25
ICPC
Fear sexually transm disease male
4.7
21.5
74
162
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
21.4
209
956
G01AA10
ATC
clindamycin; vaginal
1.8
21.1
425
2587
B37.4
ICD-10 Finland
Candidiasis of other urogenital sites
28.3
20.9
28
10
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
20.3
455
2859
N05AH04
ATC
quetiapine; oral
1.7
20.3
443
2764
U02
ICPC
Urinary frequency/urgency
1.9
20.1
300
1641
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.8
20.1
354
2058
SPAT1324
SPAT
Screening procedure
0.5
20.0
213
3745
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
19.8
381
2282
D06BB10
ATC
imiquimod; topical
2.8
19.4
126
461
N76.2
ICD-10 Finland
Acute vulvitis
10.1
19.4
38
38
J01FF01
ATC
clindamycin; systemic
1.6
19.0
555
3748
N05CF01
ATC
zopiclone; oral
1.6
18.8
536
3600
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
18.8
297
1661
J01FA06
ATC
roxithromycin; oral
1.5
18.6
845
6351
A51.0
ICD-10 Finland
Primary genital syphilis
191.4
18.6
19
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
18.5
167
734
N03AX16
ATC
pregabalin; oral
1.7
18.5
425
2684
R21
ICPC
Throat symptom/complaint
1.6
18.5
624
4373
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
18.3
422
2665
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
18.2
520
3487
B00.0
ICD-10 Finland
Eczema herpeticum
11.1
18.2
34
31
WX002
NOMESCO Finland
Sedation and analgesia
1.8
18.1
343
2039
N02BE01
ATC
paracetamol; systemic, rectal
1.6
17.9
1856
16583
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
17.6
1699
14895
N30.0
ICD-10 Finland
Acute cystitis
1.8
17.6
308
1783
B00.1
ICD-10 Finland
Herpesviral vesicular dermatitis
6.3
17.4
46
74
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
17.4
275
1534
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
17.4
471
3111
M01AB05
ATC
diclofenac; systemic, rectal
1.5
17.1
1407
11884
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.0
17.1
220
1137
R51.80
ICD-10 Finland
Headache
1.7
16.8
397
2521
A02BC05
ATC
esomeprazole; systemic
1.5
16.8
752
5604
N48.1
ICD-10 Finland
Balanoposthitis
4.8
16.7
56
120
M01AE02
ATC
naproxen; oral, rectal
1.4
16.6
1288
10721
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
16.6
258
1432
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
90.7
16.6
18
*
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.6
16.4
127
514
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.6
16.4
490
3315
Y72
ICPC
Genital herpes male
40.4
16.3
20
5
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.8
16.1
313
1870
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
2.6
16.1
122
490
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.9
16.1
236
1282
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
10.1
15.9
31
31
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
15.8
794
6040
D11
ICPC
Diarrhoea
1.8
15.8
321
1947
R53
ICD-10 Finland
Malaise and fatigue
1.6
15.7
432
2855
KGD10
NOMESCO Finland
Destruction of lesion of penis
161.0
15.5
16
*
N30
ICD-10 Finland
Cystitis
2.0
15.2
198
1026
R03AC02
ATC
salbutamol; inhalant
1.4
14.9
1164
9616
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
14.8
713
5360
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
14.7
402
2649
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
14.7
204
1084
N06AX16
ATC
venlafaxine; oral
1.7
14.7
360
2304
R30.0
ICD-10 Finland
Dysuria
2.8
14.7
94
341
H02AB07
ATC
prednisone; oral
1.8
14.7
261
1513
N05BA01
ATC
diazepam; systemic, rectal
1.8
14.6
245
1395
R05
ICPC
Cough
1.6
14.6
476
3281
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
14.6
264
1544
N06AB10
ATC
escitalopram; oral
1.5
14.5
538
3821
J02AC02
ATC
itraconazole; systemic
1.7
14.5
364
2344
A54.6
ICD-10 Finland
Gonococcal infection of anus and rectum
150.9
14.5
15
*
Z01.2
ICD-10 Finland
Dental examination
1.4
14.5
962
7699
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
14.4
542
3859
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.6
14.3
431
2907
WW200
NOMESCO Finland
Immunization
3.0
14.3
82
277
R50.9
ICD-10 Finland
Fever, unspecified
1.7
14.3
290
1755
R06AE07
ATC
cetirizine; oral
1.4
14.2
1024
8307
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
14.2
683
5128
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
14.1
341
2171
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
14.1
374
2440
R05FB02
ATC
cough suppressants and expectorants
1.5
14.1
650
4837
J01DA01
ATC
[U] cefalexin; systemic
1.4
13.9
1362
11660
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
13.8
1155
9607
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
1.9
13.7
206
1127
E0000UV
ATC
NA
1.4
13.7
859
6783
M25.5
ICD-10 Finland
Pain in joint
1.5
13.6
601
4428
S71
ICPC
Herpes simplex
6.3
13.5
35
56
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.7
13.5
294
1817
A54.5
ICD-10 Finland
Gonococcal pharyngitis
140.8
13.5
14
*
A60
ICD-10 Finland
Anogenital herpesviral [herpes simplex] infection
140.8
13.5
14
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.2
13.4
139
655
U01
ICPC
Dysuria/painful urination
2.0
13.4
184
975
N77.0
ICD-10 Finland
Ulceration of vulva in infectious and parasitic diseases classified elsewhere
18.3
13.4
20
11
U71
ICPC
Cystitis/urinary infection other
2.2
13.2
137
644
WX110
NOMESCO Finland
Local anesthesy
1.4
13.2
1600
14155
H02AB04
ATC
methylprednisolone; systemic
1.7
13.2
265
1598
C05AA08
ATC
fluocortolone; rectal, topical
1.8
13.1
253
1507
X92
ICPC
Chlamydia infection genital female
3.2
13.1
67
211
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
2.5
13.1
106
441
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.1
13.0
145
708
TKC20
NOMESCO Finland
Catheterisation of bladder
2.5
12.9
99
401
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
12.9
246
1460
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
22.7
12.9
18
8
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
12.8
215
1222
X15
ICPC
Vaginal symptom/complaint other
2.2
12.7
131
615
N76.6
ICD-10 Finland
Ulceration of vulva
5.3
12.7
38
73
H02AB06
ATC
prednisolone; systemic
1.4
12.7
874
6989
X14
ICPC
Vaginal discharge
2.5
12.7
97
392
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.4
12.6
107
458
N06AX21
ATC
duloxetine; oral
1.8
12.6
240
1421
N51.8
ICD-10 Finland
Other disorders of male genital organs in diseases classified elsewhere
32.2
12.6
16
5
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
12.5
1213
10275
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
12.5
302
1917
N06AB03
ATC
fluoxetine; oral
1.7
12.5
272
1678
N01
ICPC
Headache
1.7
12.5
296
1873
A11
ICPC
Chest pain NOS
2.3
12.4
116
520
R06.0
ICD-10 Finland
Dyspnoea
1.6
12.4
392
2671
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
12.3
389
2652
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
12.2
652
4966
S29
ICPC
Skin symptom/complaint other
1.7
12.1
296
1887
LCH11
NOMESCO Finland
Pharmacologic abortion
1.9
12.0
175
947
XKD00
NOMESCO Finland
Uroflowmetry
2.0
12.0
165
875
R03BA02
ATC
budesonide; inhalant
1.6
12.0
362
2441
R05
ICD-10 Finland
Cough
1.6
11.9
347
2314
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
4.2
11.9
44
106
L12
ICPC
Hand/finger symptom/complaint
1.6
11.9
291
1855
C07AA05
ATC
propranolol; systemic
1.5
11.9
440
3110
R42
ICD-10 Finland
Dizziness and giddiness
1.6
11.8
343
2286
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
11.8
491
3557
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
2.9
11.8
71
251
R2110
NOMESCO Finland
Giving the first information
1.9
11.7
183
1017
LEB00
NOMESCO Finland
Biopsy of vagina
3.7
11.7
50
137
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.5
11.7
540
3990
UJH02
NOMESCO Finland
Anoscopy
2.6
11.6
85
337
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
11.6
152
788
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
11.6
584
4392
LCA06
NOMESCO Finland
Biopsy of endometrium
1.7
11.6
262
1633
U13
ICPC
Bladder symptom/complaint other
2.9
11.6
68
237
L03
ICPC
Low back symptom/complaint
1.5
11.4
499
3647
WX110
SPAT
NA
2.2
11.3
114
530
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
1.8
11.3
194
1114
L82
ICD-10 Finland
Seborrhoeic keratosis
1.8
11.2
205
1197
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.1
11.1
133
667
WX892
NOMESCO Finland
Monitored bed care
2.1
11.1
118
566
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.8
11.0
186
1061
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
11.0
458
3312
L17
ICPC
Foot/toe symptom/complaint
1.5
10.9
438
3144
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.4
10.9
808
6501
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
2.3
10.8
98
435
R51
ICD-10 Finland
Headache
2.0
10.8
144
754
UKC02
NOMESCO Finland
Cystoscopy
1.8
10.8
193
1121
D07CC01
ATC
betamethasone and antibiotics; topical
1.7
10.8
256
1619
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
10.7
845
6863
X58
ICD-10 Finland
Exposure to other specified factors
1.6
10.6
289
1891
L02
ICPC
Back symptom/complaint
1.7
10.6
203
1206
L05
ICPC
Flank/axilla symptom/complaint
2.3
10.5
99
448
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
10.5
2107
19909
X57
ICD-10 Finland
Unspecified privation
3.2
10.5
53
167
R83
ICPC
Respiratory infection other
1.4
10.5
701
5534
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
10.5
334
2274
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
2.6
10.5
74
289
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
10.4
393
2783
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.6
10.4
317
2138
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
2.6
10.4
73
284
R4120
NOMESCO Finland
Occupational therapy
2.1
10.3
119
589
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
10.3
87
375
S18
ICPC
Laceration/cut
1.4
10.3
672
5279
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
9.9
549
4184
XCK10
NOMESCO Finland
Photography of fundus of eye
1.9
9.9
141
761
J20
ICD-10 Finland
Acute bronchitis
1.8
9.8
182
1072
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
9.7
320
2194
A02BC03
ATC
lansoprazole; oral
1.4
9.7
449
3310
M54.5
ICD-10 Finland
Low back pain
1.4
9.7
681
5405
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
5.1
9.7
29
57
XQ800
NOMESCO Finland
Prick test
1.7
9.7
193
1161
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.5
9.7
73
297
N03AE01
ATC
clonazepam; systemic
2.1
9.6
105
511
ZXA00
NOMESCO Finland
Right side
1.5
9.6
368
2610
N06BA04
ATC
methylphenidate; oral
2.4
9.6
81
348
M01AH05
ATC
etoricoxib; oral
1.3
9.6
1169
10091
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
9.5
166
960
S06.0
ICD-10 Finland
Concussion
1.7
9.5
211
1309
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
3.1
9.5
49
158
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.4
9.5
78
332
ZXC10
NOMESCO Finland
Use of laser
3.2
9.4
48
153
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
9.4
179
1061
D07AB08
ATC
desonide; topical
1.7
9.4
217
1362
G02.0*B00.3
ICD-10 Finland
Herpesviral meningitis
100.4
9.4
10
*
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.7
9.4
187
1122
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
9.4
165
956
U07
ICPC
Urine symptom/complaint other
2.2
9.4
89
407
L01
ICPC
Neck symptom/complaint
1.6
9.4
283
1904
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.3
1076
9199
K08.80
ICD-10 Finland
Toothache NOS
1.7
9.3
194
1184
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
9.2
255
1679
F45.8
ICD-10 Finland
Other somatoform disorders
1.7
9.2
207
1291
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
2.5
9.1
72
298
R35
ICD-10 Finland
Polyuria
2.2
9.1
92
432
G01AF05
ATC
econazole; vaginal
1.7
9.1
176
1051
AA1AD
NOMESCO Finland
CT of head and brain
1.5
9.1
297
2034
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.3
9.0
81
360
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.5
9.0
285
1934
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.1
9.0
100
487
R07.3
ICD-10 Finland
Other chest pain
1.8
9.0
147
831
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
9.0
124
661
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
9.0
579
4523
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
9.0
314
2184
D01
ICPC
Abdominal pain/cramps general
1.6
8.9
250
1651
G03HB01
ATC
cyproterone and estrogen; systemic
1.5
8.9
332
2341
L08
ICPC
Shoulder symptom/complaint
1.5
8.9
290
1985
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.9
8.8
134
740
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
8.7
174
1045
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
8.7
623
4945
T78.4
ICD-10 Finland
Allergy, unspecified
1.9
8.7
122
655
R01AD09
ATC
mometasone; nasal
1.3
8.7
1013
8641
TQW02
NOMESCO Finland
Removal of wart
50.2
8.7
10
*
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
7.7
8.6
19
25
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
8.6
398
2928
M79.1
ICD-10 Finland
Myalgia
1.5
8.6
271
1839
D10
ICPC
Vomiting
1.7
8.5
184
1132
J01AA04
ATC
lymecycline; systemic
1.5
8.5
328
2324
G01AF04
ATC
miconazole; vaginal
2.0
8.5
108
559
H01.0
ICD-10 Finland
Blepharitis
1.9
8.5
120
646
K10.3
ICD-10 Finland
Alveolitis of jaws
1.9
8.5
124
676
Z01.7
ICD-10 Finland
Laboratory examination
1.6
8.5
209
1335
M54
ICD-10 Finland
Dorsalgia
1.6
8.4
242
1605
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
3.0
8.4
46
155
A04
ICPC
Weakness/tiredness general
1.5
8.4
258
1737
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
8.4
231
1516
P06
ICPC
Sleep disturbance
1.6
8.4
214
1378
J01MA01
ATC
ofloxacin; systemic
1.9
8.4
123
673
XLA10
NOMESCO Finland
NA
2.0
8.4
104
532
ZXA10
NOMESCO Finland
Bilateral
1.5
8.4
280
1926
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
+∞
8.3
8
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
8.3
91
444
B00.5
ICD-10 Finland
Herpesviral ocular disease
10.8
8.3
15
14
F29
ICPC
Eye symptom/complaint other
1.7
8.3
156
922
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.5
8.2
250
1682
G44.2
ICD-10 Finland
Tension-type headache
1.5
8.2
297
2079
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
8.2
159
948
N05BA12
ATC
alprazolam; oral
1.7
8.2
187
1169
H92.0
ICD-10 Finland
Otalgia
1.9
8.2
117
630
S21
ICPC
Skin texture symptom/complaint
1.6
8.2
204
1306
R06AX27
ATC
desloratadine; oral
1.3
8.2
662
5350
N03AX09
ATC
lamotrigine; oral
1.8
8.1
132
744
KMAK
NOMESCO Finland
NA
1.3
8.1
1257
11093
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
8.1
162
977
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
1.8
8.1
130
732
M54.8
ICD-10 Finland
Other dorsalgia
2.1
8.1
84
399
N87.0
ICD-10 Finland
Mild cervical dysplasia
2.2
8.1
79
365
N48.8
ICD-10 Finland
Other specified disorders of penis
6.8
8.1
19
28
RS221
NOMESCO Finland
NA
3.8
8.0
32
85
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.8
8.0
51
188
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
6.3
8.0
20
32
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
8.0
147
865
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
8.0
305
2160
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.9
8.0
123
681
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.0
8.0
101
521
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.0
7.9
103
537
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
7.9
307
2179
R00.2
ICD-10 Finland
Palpitations
1.7
7.9
146
857
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
7.9
155
931
W22
ICD-10 Finland
Striking against or struck by other object(s)
1.8
7.9
126
706
T74.1
ICD-10 Finland
Physical abuse
2.5
7.9
59
241
Y04
ICPC
Penis symptom/complaint other
7.8
7.9
17
22
A02BC01
ATC
omeprazole; systemic
1.4
7.8
450
3437
E000001
ATC
NA
1.4
7.8
436
3312
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.6
7.8
193
1234
J01CA04
ATC
amoxicillin; systemic
1.3
7.8
1877
17542
N76
ICD-10 Finland
Other inflammation of vagina and vulva
3.0
7.8
42
141
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.1
7.8
80
380
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.6
7.8
214
1405
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.3
7.8
72
325
A29
ICPC
General symptom/complaint other
1.7
7.8
172
1069
J01AA07
ATC
tetracycline; systemic
1.4
7.8
378
2805
F60.9
ICD-10 Finland
Personality disorder, unspecified
2.7
7.8
50
187
R52.2
ICD-10 Finland
Other chronic pain
2.4
7.7
64
275
G01AF01
ATC
metronidazole; vaginal
1.7
7.7
165
1014
M54.2
ICD-10 Finland
Cervicalgia
1.7
7.7
143
844
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.2
7.7
77
361
A98
ICPC
Health maint/preventive medicine
1.9
7.7
2284
22244
N30.9
ICD-10 Finland
Cystitis, unspecified
1.9
7.6
113
622
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
7.6
250
1713
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
7.6
373
2772
D07AD01
ATC
clobetasol; topical
1.5
7.5
255
1756
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
1.8
7.5
120
676
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
7.5
317
2288
EB1AA
SPAT
NA
1.9
7.5
100
527
TAB00
NOMESCO Finland
Lumbar puncture
1.9
7.5
98
513
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
7.5
94
485
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
7.5
232
1568
F41.8
ICD-10 Finland
Other specified anxiety disorders
2.1
7.5
83
408
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.8
7.5
121
682
R01AD08
ATC
fluticasone; nasal
1.3
7.5
608
4902
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.3
7.4
65
289
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.4
833
7027
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
1.8
7.3
121
687
L02.8
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of other sites
3.0
7.3
39
131
G05.1*B00.4
ICD-10 Finland
Herpesviral meningoencephalitis
+∞
7.3
7
*
N01BB02
ATC
lidocaine; parenteral
4.2
7.3
26
63
A10AE04
ATC
insulin glargine; parenteral
1.7
7.3
135
795
N06AA09
ATC
amitriptyline; systemic
1.7
7.3
137
813
A48
ICPC
General and Unspecified, Clarification/discussion RFE/demand
1.7
7.2
140
838
F32.1
ICD-10 Finland
Moderate depressive episode
1.7
7.2
150
917
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
7.2
1292
11539
I84
ICD-10 Finland
Hemorrhoids
2.4
7.2
57
240
D06
ICPC
Abdominal pain localized other
1.6
7.2
169
1066
A01
ICPC
Pain general/multiple sites
1.7
7.2
131
771
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.6
7.2
30
84
F41.1
ICD-10 Finland
Generalized anxiety disorder
1.7
7.2
143
865
P01
ICPC
Feeling anxious/nervous/tense
1.4
7.1
334
2456
H00.00
ICD-10 Finland
Hordeolum
2.0
7.1
91
475
N03AX12
ATC
gabapentin; oral
1.5
7.1
243
1680
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
7.1
97
519
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.5
7.1
31
90
D09
ICPC
Nausea
1.8
7.1
112
629
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
7.1
114
646
A02BC04
ATC
rabeprazole; oral
1.7
7.1
155
962
N06AX05
ATC
trazodone; oral
2.3
7.0
60
264
127
Kela drug reimbursment
Transplant complication
3.4
7.0
32
96
S12
ICPC
Insect bite/sting
1.9
7.0
102
557
R52.9
ICD-10 Finland
Pain, unspecified
1.7
7.0
148
909
G43.9
ICD-10 Finland
Migraine, unspecified
1.6
7.0
178
1148
R03AC03
ATC
terbutaline; inhalant
1.5
7.0
276
1968
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
2.6
7.0
49
194
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.7
7.0
129
763
O99.80
ICD-10 Finland
The fear of childbirth
1.6
6.9
176
1134
M01AG02
ATC
tolfenamic acid; oral, rectal
1.4
6.9
342
2543
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
6.9
354
2649
Z72.2
ICD-10 Finland
Drug use
4.1
6.9
25
62
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
6.9
87
453
W79
ICPC
Unwanted pregnancy
2.2
6.9
66
306
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
1.9
6.9
97
526
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.8
1328
11941
U29
ICPC
Urinary symptom/complaint other
2.6
6.8
45
172
A01AB09
ATC
miconazole; local oral
1.7
6.8
129
767
M01AH02
ATC
rofecoxib; oral
1.6
6.8
151
942
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
6.8
139
847
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
6.7
653
5385
D07AC01
ATC
betamethasone; topical
1.3
6.7
592
4816
A87.9
ICD-10 Finland
Viral meningitis, unspecified
4.3
6.7
23
54
H10
ICD-10 Finland
Conjunctivitis
1.7
6.7
145
895
N06AB05
ATC
paroxetine; oral
1.7
6.7
130
779
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.8
6.7
40
145
G04CA02
ATC
tamsulosin; oral
1.6
6.7
164
1049
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
3.7
6.7
27
74
EB1SA
SPAT
NA
1.9
6.6
89
472
R02
ICPC
Shortness of breath/dyspnoea
1.6
6.6
188
1245
H57.1
ICD-10 Finland
Ocular pain
2.1
6.6
74
366
A10AA02
ATC
NA
2.2
6.6
65
306
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.1
6.6
71
344
B02.9
ICD-10 Finland
Zoster without complication
2.1
6.6
72
355
A99
ICPC
Disease/condition unspecnature/site
1.7
6.6
129
777
R06AX22
ATC
ebastine; oral
1.4
6.6
366
2776
D02AE01
ATC
carbamide; topical
1.7
6.5
125
745
B00.8
ICD-10 Finland
Other forms of herpesviral infection
10.0
6.5
12
12
F90.0
ICD-10 Finland
Disturbance of activity and attention
1.9
6.5
88
468
D07AC13
ATC
mometasone; topical
1.3
6.5
525
4215
TQW99
NOMESCO Finland
Other minor procedure on skin
2.2
6.5
62
288
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.8
6.5
100
559
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
6.5
1170
10402
LDA10
NOMESCO Finland
Curettage of cervix uteri
1.8
6.5
105
594
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
6.5
1524
13972
F32
ICD-10 Finland
Depressive episode
1.6
6.4
141
876
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
6.4
261
1869
N87.1
ICD-10 Finland
Moderate cervical dysplasia
2.1
6.4
65
308
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
2.6
6.4
42
161
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
3.3
6.4
30
93
L04AA01
ATC
[U] ciclosporin; systemic
3.3
6.4
30
93
M79.7
ICD-10 Finland
Fibromyalgia
2.0
6.4
77
395
L04AD01
ATC
ciclosporin; systemic
2.7
6.3
41
154
TQW40
NOMESCO Finland
Remowal of suture of skin
1.7
6.3
113
662
B00
ICD-10 Finland
Herpesviral [herpes simplex] infections
6.6
6.3
15
23
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
1.6
6.3
154
984
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.5
6.3
190
1276
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.3
694
5815
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.0
6.3
78
404
J01
ICD-10 Finland
Acute sinusitis
1.7
6.3
116
688
G50.1
ICD-10 Finland
Atypical facial pain
2.7
6.3
39
146
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.0
6.3
76
391
WX290
NOMESCO Finland
Other blockade of nerve
1.2
6.2
1101
9745
X16
ICPC
Vulval symptom/complaint
2.5
6.2
45
182
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.7
6.2
114
674
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.3
6.2
51
220
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.6
6.2
165
1076
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.6
6.2
154
988
B18.2
ICD-10 Finland
Chronic viral hepatitis C
2.8
6.2
37
135
J35.0
ICD-10 Finland
Chronic tonsillitis
1.6
6.2
165
1081
A03
ICPC
Fever
1.3
6.1
391
3029
R03BA01
ATC
beclometasone; inhalant
1.5
6.1
239
1699
D06BX01
ATC
metronidazole; topical
1.5
6.1
191
1297
E000006
ATC
NA
1.7
6.1
124
754
NDS00
NOMESCO Finland
Incision and debridement of infection of tendon of wrist or hand
12.5
6.1
10
8
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.8
6.1
98
558
6BA02
NOMESCO Finland
NA
8.6
6.1
12
14
R25.2
ICD-10 Finland
Cramp and spasm
2.6
6.0
41
162

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1309
7991
2.27
90.68
2.7
2.0
—
—
—
0
0
965
5449
2.22
77.94
2.1
1.7
—
—
—
0
0
412
1796
2.53
58.54
2.7
2.4
34.2
62.8
u/l
0.55
362
1542
1030
6574
1.93
54.92
6.8
5.8
—
—
—
0
0
522
2689
2.17
49.79
2.8
2.6
3.4
3.4
e6/l
0.03
258
1397
1036
6844
1.85
47.94
3.9
3.2
61.6
72.1
e6/l
0.26
665
4534
1369
9861
1.81
47.47
7.1
5.7
2.8
2.8
%
0.31
1257
9233
1329
9489
1.81
47.45
7.2
5.8
0.7
0.7
%
1.34
1212
8909
813
5009
1.90
46.58
3.1
2.6
—
—
—
0
0
1372
9926
1.80
46.52
7.4
6.0
8.0
8.0
%
0.02
1267
9380
90
171
5.41
45.20
1.2
1.2
—
—
—
0
0
649
3754
1.97
44.62
2.1
1.6
—
—
—
0
0
1410
10371
1.78
44.36
7.2
5.7
30.3
29.5
%
2.24
1296
9765
1394
10234
1.77
44.01
7.0
5.5
55.7
56.6
%
2.32
1285
9664
800
4979
1.87
43.94
3.2
2.7
0.3
0.3
e6/l
0.13
571
3688
1054
7185
1.78
42.58
5.9
5.1
1.2
1.2
mmol/l
0.38
963
6561
1857
14906
1.84
42.47
5.1
3.8
—
—
—
0
0
527
2890
2.03
41.87
2.7
2.4
0.8
1.2
e6/l
1.15
261
1591
752
4652
1.86
41.72
4.2
3.4
96.2
96.1
%
0.03
733
4516
1786
14209
1.80
41.59
5.0
3.7
50.3
752.6
e6/l
—
7
158
1417
10565
1.74
41.31
7.1
5.7
0.0
0.0
e9/l
0.22
1215
9325
1413
10533
1.74
41.17
7.1
5.7
0.5
0.5
e9/l
0.15
1216
9307
1452
10940
1.73
40.39
7.6
6.0
0.2
0.2
e9/l
0.05
1256
9845
844
5462
1.80
40.13
3.3
2.8
34.1
92.5
e6/l
1.25
612
4120
793
5038
1.82
40.09
1.6
1.4
2.2
2.2
g/l
0.06
448
3300
987
6695
1.76
39.89
1.9
1.7
101.5
97.9
pmol/l
1.47
531
3723
49
55
9.06
39.88
1.4
1.3
—
—
—
0
0
1554
11988
1.72
39.14
9.7
8.4
3.9
4.0
e9/l
2.21
1328
10613
1447
10954
1.71
38.99
7.1
5.7
2.0
2.0
e9/l
0.16
1268
9889
780
5040
1.78
36.64
8.0
6.2
—
—
—
0
0
1020
7191
1.68
34.51
4.9
4.4
37.1
36.8
g/l
0.92
935
6732
1111
8088
1.65
32.68
6.3
5.6
1.2
1.2
mmol/l
0.45
982
6818
1799
14787
1.69
32.55
8.1
6.5
71.1
72.6
u/l
0.77
1705
13992
1246
9431
1.61
30.63
5.9
5.4
10.5
10.3
umol/l
0.24
1174
8881
1142
8525
1.60
29.32
2.2
1.9
—
—
—
0
0
709
4757
1.67
27.68
4.3
3.4
7.4
7.4
ph
1.84
87
944
429
2550
1.82
25.57
1.2
1.2
—
—
—
0
0
807
5687
1.60
25.50
3.3
3.0
2.3
2.3
mmol/l
0.12
700
5165
704
4803
1.64
25.38
2.2
2.0
—
—
—
0
0
558
3584
1.71
25.37
1.5
1.4
20.9
20.6
nmol/l
0.26
494
3187
834
5945
1.59
25.01
1.4
1.3
2.2
1.5
u/ml
0.49
186
1741
890
6477
1.57
24.23
2.3
2.0
—
—
—
0
0
2379
21717
2.00
24.17
15.8
10.9
40.2
40.2
%
0.00
2054
17904
70
181
3.95
24.13
2.5
2.4
49.0
43.9
%
—
7
26
373
2178
1.83
23.44
3.0
2.4
6.7
6.7
umol/l
0.01
303
1856
2408
22126
2.05
23.22
14.7
10.3
20.0
19.9
mg/l
0.07
1901
17062
406
2465
1.77
22.31
1.8
1.5
—
—
—
0
0
2260
20410
1.76
22.22
5.5
4.7
1.7
2.0
mu/l
1.52
2131
19361
1796
15353
1.54
22.14
4.4
3.6
9.0
9.3
mm/h
0.54
1676
14424
436
2711
1.73
22.01
2.8
2.5
2.4
2.4
mmol/l
0.04
368
2395
195
929
2.19
21.82
2.0
1.7
—
—
—
0
0
62
159
3.97
21.63
2.4
2.8
812.1
793.5
e6/l
0.06
16
62
387
2341
1.77
21.49
1.7
1.6
—
—
—
0
0
1087
8428
1.49
21.27
2.4
2.2
75.4
72.9
nmol/l
2.14
998
7867
500
3259
1.66
21.08
1.4
1.4
595.7
530.8
titre
0.27
103
627
52
119
4.44
21.07
2.7
3.1
42.3
45.8
%
0.46
14
38
530
3514
1.64
20.87
2.8
2.4
536.4
550.2
mosm/kgh2o
0.66
444
2997
696
4936
1.56
20.59
1.9
1.7
0.7
0.9
mg/l
1.11
481
3591
2304
21038
1.77
20.27
13.6
10.2
139.5
139.5
mmol/l
1.00
2247
20455
591
4049
1.59
20.27
4.9
3.9
—
—
—
0
0
149
656
2.35
20.12
1.3
1.1
—
—
—
0
0
405
2526
1.71
20.08
3.8
3.3
0.8
0.8
mmol/l
0.02
376
2366
341
2031
1.78
19.88
1.2
1.2
—
—
—
0
0
558
3796
1.60
19.64
2.6
2.3
11.2
7.9
e6/l
0.47
481
3319
670
4757
1.55
19.56
2.2
2.0
135.7
215.4
u/l
1.58
634
4528
401
2516
1.70
19.41
2.0
1.9
—
—
—
0
0
2305
21115
1.74
19.19
13.9
10.3
3.9
3.9
mmol/l
3.71
2245
20477
497
3307
1.62
19.12
2.5
2.5
91.8
106.8
ug/g
0.47
389
2640
751
5493
1.51
19.01
2.6
2.3
—
—
—
0
0
443
2869
1.65
18.98
3.4
3.0
323.8
394.8
ng/l
0.16
250
1621
874
6614
1.48
18.65
1.8
1.7
—
—
—
0
0
125
531
2.42
18.30
1.8
1.7
—
—
—
0
0
661
4743
1.53
18.17
3.2
3.1
—
—
—
0
0
1996
17781
1.51
17.44
4.6
4.1
14.2
14.3
pmol/l
2.49
1845
16658
367
2320
1.68
17.14
1.6
1.4
—
—
—
0
0
1401
11708
1.42
17.01
3.3
2.9
76.1
77.9
ug/l
0.16
1315
11089
144
673
2.21
16.90
3.3
3.7
24.3
24.1
mmol/l
0.33
135
610
396
2578
1.63
16.45
1.6
1.6
1011.8
1189.5
nmol/l
4.01
293
2011
1318
10941
1.41
16.36
5.2
4.1
6.3
6.3
mmol/l
0.28
1207
9857
154
753
2.11
16.12
5.2
3.1
—
—
—
0
0
272
1613
1.77
15.97
2.7
2.3
17.5
23.2
au/ml
0.79
17
136
305
1894
1.69
15.16
7.8
5.4
1.0
1.0
mmol/l
0.43
293
1779
254
1499
1.77
15.15
1.4
1.3
22.7
37.5
au/ml
—
6
65
138
665
2.13
15.01
1.1
1.1
—
—
—
0
0
327
2077
1.66
14.90
1.4
1.3
—
—
—
0
0
2127
19389
1.51
14.86
17.2
12.4
13.4
13.4
%
1.07
2100
19000
2450
23132
1.86
14.62
10.9
8.3
25.8
25.9
u/l
0.11
2384
22475
240
1409
1.77
14.56
1.2
1.2
—
—
—
0
0
775
5952
1.43
14.52
3.1
2.7
19.0
35.0
ng/l
2.55
335
2809
106
471
2.30
14.07
1.4
1.4
285.0
310.3
ug/g
0.52
55
237
144
724
2.05
14.01
2.4
2.0
1.1
1.2
g/l
0.46
137
682
140
698
2.06
13.94
2.4
2.0
0.2
0.2
g/l
1.34
132
657
322
2078
1.63
13.73
2.0
2.1
372.6
376.8
nmol/l
0.17
295
1924
222
1306
1.76
13.37
1.5
1.3
—
—
—
0
0
646
4862
1.44
13.33
2.2
2.1
2.6
2.7
mg/l
0.52
521
4219
1148
9520
1.37
13.30
9.7
7.9
0.0
0.0
e9/l
0.77
904
7872
208
1204
1.79
13.23
6.5
3.2
—
—
—
0
0
532
3892
1.46
12.70
1.3
1.3
9.0
9.3
u/ml
0.04
194
1674
145
759
1.96
12.62
1.2
1.2
—
—
—
0
0
211
1244
1.76
12.61
6.4
7.1
1.2
1.3
mmol/l
0.80
198
1201
198
1146
1.79
12.60
7.9
8.7
—
—
—
0
0
252
1565
1.67
12.46
3.2
2.6
10.3
10.6
g/l
0.58
239
1449
401
2786
1.52
12.33
2.4
2.2
14.8
14.6
umol/l
0.24
374
2584
118
582
2.08
12.12
4.2
3.1
0.2
0.3
g/l
0.54
79
241
106
503
2.15
12.04
3.0
2.8
—
—
—
0
0
353
2401
1.54
11.96
2.1
2.1
29.4
29.4
s
0.01
346
2316
634
4841
1.41
11.87
1.6
1.6
1.3
1.4
mmol/l
1.20
570
4228
256
1628
1.63
11.53
3.8
2.4
—
—
—
0
0
567
4268
1.42
11.47
3.2
2.8
—
—
—
0
0
644
4961
1.39
11.38
4.5
3.3
8.2
8.1
mmol/l
0.20
559
4296
1260
10780
1.32
11.11
5.1
4.2
0.0
0.0
estimate
0.50
198
2238
1779
15994
1.35
11.10
3.5
2.8
35.1
37.1
u/l
0.74
1698
15299
220
1364
1.67
10.94
4.1
2.4
—
—
—
0
0
358
2496
1.50
10.75
2.4
2.2
2.4
2.5
g/l
0.49
330
2313
236
1499
1.63
10.68
3.6
3.4
—
—
—
0
0
196
1187
1.70
10.65
2.0
1.8
1.3
1.3
g/l
0.03
179
1114
329
2258
1.52
10.65
2.5
2.3
25.5
24.2
%
0.90
290
1956
1264
10875
1.31
10.47
3.5
3.1
0.0
0.0
estimate
1.06
195
2171
110
563
2.00
10.26
1.2
1.1
—
—
—
0
0
110
563
2.00
10.26
1.2
1.1
—
—
—
0
0
268
1772
1.57
10.25
3.8
2.3
—
—
—
0
0
267
1767
1.57
10.17
3.8
2.0
—
—
—
0
0
170
1005
1.74
10.08
2.9
2.6
4.5
4.7
kpa
0.91
163
973
265
1756
1.57
10.04
3.8
2.3
—
—
—
0
0
541
4134
1.39
9.86
1.4
1.3
28.5
23.2
iu/ml
0.46
151
1233
198
1228
1.66
9.84
3.6
3.5
5.8
5.8
kpa
0.03
192
1194
45
160
2.84
9.54
2.3
2.6
525.1
497.6
e6/l
0.20
36
130
261
1744
1.55
9.52
3.3
2.3
—
—
—
0
0
44
156
2.85
9.38
2.4
2.6
0.2
0.2
e9/l
0.37
36
130
1243
10769
1.29
9.38
3.5
3.1
0.0
0.0
estimate
0.50
193
2175
223
1446
1.59
9.27
2.7
2.3
0.2
0.2
g/l
0.68
210
1360
1952
17977
1.33
9.18
4.7
4.2
37.6
37.7
mmol/mol
0.09
1834
17034
73
334
2.22
9.15
1.7
1.7
38.7
38.8
g/l
0.02
63
297
729
5900
1.33
9.04
2.9
2.4
55.9
55.6
u/l
0.08
675
5499
192
1216
1.62
8.80
3.6
3.5
1.5
1.8
mmol/l
0.56
171
964
81
393
2.09
8.78
1.2
1.1
—
—
—
0
0
161
975
1.69
8.77
2.6
2.3
65.8
67.8
g/l
2.66
148
909
66
295
2.27
8.76
2.4
2.6
—
—
—
0
0
1456
12941
1.28
8.70
3.1
2.9
—
—
—
0
0
125
711
1.80
8.49
1.3
1.2
—
—
—
0
0
154
931
1.69
8.45
1.7
1.7
—
—
—
0
0
203
1324
1.58
8.24
2.3
2.1
13.2
11.2
nmol/l
2.56
172
1197
581
4618
1.33
8.04
2.6
2.2
2255.9
3525.2
umol/l
0.60
508
4134
221
1479
1.54
8.01
2.7
2.6
1.8
1.7
%
0.42
195
1318
2115
19839
1.34
7.86
3.8
3.4
5.7
5.7
mmol/l
0.06
1963
18610
228
1546
1.52
7.78
2.0
2.4
4.2
4.1
e9/l
0.08
166
1316
50
209
2.42
7.76
2.4
2.6
1.2
1.2
e9/l
0.00
25
122
80
409
1.99
7.57
1.1
1.1
—
—
—
0
0
184
1200
1.57
7.49
8.2
7.3
7.5
7.6
mmol/l
0.11
175
1151
724
5989
1.29
7.38
6.5
5.9
1.1
1.1
inr
0.14
206
2033
101
569
1.81
7.14
2.0
2.1
1.3
1.4
g/l
0.20
90
498
1178
10360
1.25
7.11
4.1
3.9
—
—
—
0
0
165
1063
1.59
7.09
1.3
1.2
—
—
—
0
0
89
484
1.87
7.04
1.9
2.3
236.1
340.1
ug/l
0.39
78
438
25
76
3.31
6.96
1.6
2.1
200.8
131.7
e6/l
0.78
13
41
127
772
1.68
6.88
2.1
2.0
—
—
—
0
0
52
234
2.25
6.87
1.2
1.4
—
—
—
0
0
254
1807
1.45
6.84
2.9
2.5
0.7
0.7
ug/l
0.06
159
1007
50
224
2.26
6.68
1.5
1.4
—
—
—
0
0
79
424
1.89
6.53
1.7
1.9
200.1
186.4
pmol/l
0.42
73
397
243
1731
1.44
6.50
1.5
1.3
202.7
199.3
u/ml
0.02
222
1616
40
166
2.43
6.36
2.3
2.2
12.0
13.7
%
0.59
26
90
2443
23616
1.48
6.30
12.1
9.6
—
—
—
0
0
158
1037
1.56
6.29
4.3
3.5
72.5
74.3
ng/l
0.15
140
936
49
224
2.21
6.26
1.5
1.4
2.9
2.9
g/l
0.07
38
153
49
224
2.21
6.26
1.5
1.4
0.4
0.4
g/l
0.01
38
152
109
654
1.70
6.23
1.9
1.7
43.5
41.8
nmol/l
0.26
103
638
49
225
2.20
6.20
1.5
1.4
6.4
6.5
g/l
0.04
37
154
68
354
1.95
6.17
1.5
1.7
0.7
0.7
g/l
0.10
54
265
85
486
1.77
5.78
1.3
1.2
3.5
3.6
mmol/l
0.49
80
453
152
1017
1.52
5.58
1.3
1.3
1.7
1.2
u/ml
0.12
11
94
27
99
2.75
5.53
3.7
3.2
—
—
—
0
0
246
1819
1.39
5.35
1.4
1.4
—
—
—
0
0
2131
20275
1.27
5.33
17.6
12.8
333.4
333.1
g/l
0.95
2121
20125
162
1110
1.49
5.32
1.1
1.1
—
—
—
0
0
2566
25171
1.80
5.21
21.1
15.2
90.6
90.0
fl
12.84
2551
24938
2564
25146
1.78
5.21
21.1
15.3
260.8
262.4
e9/l
0.62
2526
24687
2566
25172
1.80
5.20
21.1
15.2
30.3
30.0
pg
11.48
2551
24937
235
1735
1.39
5.16
1.5
1.6
294.0
297.3
mu/l
0.08
216
1540
40
183
2.20
5.16
1.2
1.1
—
—
—
0
0
2567
25187
1.80
5.16
21.3
15.3
134.9
135.7
g/l
2.50
2552
24948
2566
25175
1.79
5.15
21.1
15.3
4.5
4.5
e12/l
8.29
2526
24692
177
1243
1.45
5.14
1.3
1.3
—
—
—
0
0
328
2555
1.32
5.10
1.2
1.2
—
—
—
0
0
2566
25180
1.78
5.07
21.2
15.3
6.7
6.8
e9/l
0.82
2527
24683
321
2496
1.33
5.05
2.5
2.3
5174.9
5981.4
u/l
0.21
116
1035
98
607
1.64
5.03
1.5
1.3
8.6
3.3
u/ml
0.89
12
64
205
1486
1.41
5.02
1.2
1.2
—
—
—
0
0
109
695
1.59
4.98
9.9
10.7
24.0
24.1
mmol/l
0.17
98
665
228
1688
1.38
4.94
3.5
3.4
4.4
4.6
pmol/l
2.06
202
1523
12
28
4.30
4.82
1.1
1.1
—
—
—
0
0
78
462
1.71
4.75
1.4
1.4
—
—
—
0
0
89
553
1.63
4.54
1.2
1.3
63.6
87.4
titre
0.70
11
57
32
141
2.29
4.54
4.1
2.9
—
—
—
0
0
481
3991
1.25
4.54
1.6
1.4
—
—
—
0
0
31
135
2.31
4.52
1.7
1.4
36.6
58.4
pmol/l
0.98
14
44
145
1007
1.47
4.50
2.7
2.6
69.3
72.5
e9/l
0.46
97
730
41
203
2.04
4.38
1.1
1.1
—
—
—
0
0
74
449
1.67
4.17
1.2
1.1
6.7
13.6
au/ml
—
6
30
122
833
1.49
4.14
3.0
2.7
7.4
7.4
ph
0.60
20
113
74
454
1.65
4.01
1.1
1.0
2.3
3.0
u/ml
0.25
34
255
203
1528
1.36
4.00
1.4
1.5
—
—
—
0
0
75
463
1.64
3.97
3.8
2.9
1.4
1.3
mg/l
0.45
68
437
32
150
2.15
3.96
2.2
1.9
—
—
—
0
0
18
64
2.82
3.95
3.6
2.6
—
—
—
0
0
468
3930
1.23
3.94
4.1
3.4
981.7
307.0
mg/l
1.25
318
2576
66
396
1.68
3.90
1.9
2.3
—
—
—
0
0
79
497
1.61
3.89
1.4
1.4
26.4
21.7
e6/l
0.15
61
380
79
497
1.61
3.89
1.5
1.4
3009.0
8677.1
e6/l
0.32
66
400
2188
21059
1.23
3.87
4.1
3.7
2.8
2.9
mmol/l
1.62
2043
19924
110
747
1.49
3.86
2.5
2.2
—
—
—
0
0
122
846
1.46
3.86
3.0
2.7
5.1
5.1
kpa
0.04
114
793
45
244
1.86
3.75
1.5
1.5
—
—
—
0
0
288
2300
1.28
3.74
1.4
1.3
—
—
—
0
0
263
2084
1.29
3.63
1.4
1.3
22.2
22.2
iu/l
0.00
214
1781
25
110
2.28
3.61
2.6
2.7
—
—
—
0
0
184
1388
1.35
3.60
1.4
1.4
—
—
—
0
0
281
2250
1.28
3.58
1.3
1.2
171.9
156.1
iu/ml
0.22
95
887
86
564
1.54
3.57
2.2
2.2
11.9
10.1
mg/l
2.49
78
532
194
1482
1.33
3.50
1.4
1.4
—
—
—
0
0
17
63
2.71
3.49
1.4
1.3
—
—
—
0
0
186
1416
1.34
3.44
1.3
1.3
210.5
240.6
miu/ml
0.49
78
729
45
252
1.80
3.42
1.6
1.3
—
—
—
0
0
45
252
1.80
3.42
1.0
1.1
1.6
1.5
g/l
0.69
39
233
193
1486
1.32
3.31
1.4
1.4
—
—
—
0
0
478
4104
1.20
3.19
5.1
4.1
12.5
10.3
mg/mmol
0.39
328
2711
31
157
1.99
3.19
1.1
1.0
—
—
—
0
0
32
164
1.96
3.19
1.1
1.1
—
—
—
0
0
86
580
1.50
3.18
1.6
1.6
—
—
—
0
0
56
342
1.65
3.16
2.1
2.1
128.1
132.7
g/l
0.85
33
257
81
541
1.51
3.14
1.4
1.2
265.4
233.3
u/ml
0.50
64
350
124
900
1.40
3.12
2.4
2.8
104.0
121.5
ng/l
0.45
109
784
33
173
1.92
3.09
2.8
4.6
—
—
—
0
0
2162
20891
1.20
3.08
3.8
3.4
4.7
4.8
mmol/l
1.02
2034
19900
10
29
3.46
3.04
1.0
1.0
—
—
—
0
0
41
233
1.77
3.00
1.4
1.6
—
—
—
0
0
113
814
1.41
2.98
1.1
1.1
3.2
4.1
u/ml
0.19
16
138
30
156
1.93
2.89
1.6
1.2
—
61.3
—
0
12
35
192
1.83
2.88
2.2
1.7
—
—
—
0
0
6
9
6.68
2.87
1.0
1.4
—
—
—
0
0
23
109
2.12
2.84
1.1
1.1
—
—
—
0
0
192
1513
1.29
2.82
16.9
14.7
1.1
1.2
inr
0.46
25
245
27
137
1.98
2.80
1.1
1.3
5.6
5.9
u/l
0.13
21
114
23
110
2.10
2.78
1.7
3.4
134.6
148.7
umol/l
—
10
59
63
411
1.55
2.75
1.3
1.3
3.7
4.4
u/ml
0.24
30
176
42
248
1.70
2.72
2.4
2.8
3.7
5.0
u/ml
0.64
35
209
38
220
1.74
2.65
1.3
1.4
414.3
336.7
pmol/l
0.55
29
172
86
606
1.43
2.60
2.5
2.4
0.6
0.7
%
2.96
86
586
7
15
4.68
2.59
1.1
1.0
—
—
—
0
0
72
491
1.48
2.58
1.6
1.3
108.8
102.7
u/ml
0.16
11
98
38
223
1.71
2.54
1.2
1.3
—
—
—
0
0
62
412
1.52
2.52
1.4
1.2
—
—
—
0
0
76
527
1.46
2.51
1.5
1.3
—
—
—
0
0
77
538
1.44
2.46
1.6
1.2
—
—
—
0
0
2145
20813
1.17
2.43
3.8
3.4
1.5
1.5
mmol/l
0.81
2006
19763
823
8966
0.88
2.39
2.2
2.2
—
—
—
0
0
82
585
1.41
2.35
3.1
2.9
—
—
—
0
0
356
3061
1.19
2.35
4.1
3.8
1.8
1.8
ug/l
0.09
320
2803
29
161
1.81
2.35
1.1
1.1
3.5
5.8
iu/ml
—
9
42
42
260
1.63
2.33
1.3
1.2
26.7
35.9
mg/l
2.65
36
210
107
802
1.35
2.29
1.8
2.1
20.3
21.0
s
1.22
97
676
20
99
2.03
2.26
1.1
1.1
—
—
—
0
0
121
926
1.32
2.25
1.7
1.7
—
—
—
0
0
11
42
2.63
2.18
1.2
1.7
—
—
—
0
0
11
42
2.63
2.18
1.6
1.5
—
—
—
0
0
101
757
1.35
2.18
2.8
2.2
4.5
5.1
umol/l
0.24
67
565
129
1002
1.30
2.17
1.8
2.1
4.7
6.6
ug/l
1.09
95
895
7
19
3.69
2.15
1.3
1.5
66.7
127.7
ng/l
—
7
19
16
74
2.17
2.14
2.6
2.2
—
—
—
0
0
32
189
1.70
2.13
2.0
1.6
—
—
—
0
0
309
3582
0.84
2.10
1.3
1.3
—
—
—
0
0
12
50
2.41
2.02
4.8
2.4
—
—
—
0
0
12
50
2.41
2.02
1.2
1.0
—
—
—
0
0
8
26
3.08
2.01
1.4
1.1
—
—
—
0
0
166
1347
1.25
1.99
1.2
1.1
79.0
97.9
titre
—
5
33
46
304
1.52
1.98
2.3
1.9
16.5
17.0
%
0.49
25
142
32
194
1.66
1.96
1.1
1.0
—
—
—
0
0
64
454
1.42
1.94
1.8
1.8
—
—
—
0
0
58
404
1.45
1.94
1.2
1.1
—
—
—
0
0
5
11
4.55
1.94
1.2
1.1
—
—
—
0
0
5
11
4.55
1.94
1.2
1.1
—
—
—
0
0
6
16
3.76
1.93
1.2
1.1
—
—
—
0
0
42
274
1.54
1.92
2.6
2.3
—
—
—
0
0
15
71
2.12
1.92
1.3
1.6
—
—
—
0
0
26
150
1.74
1.90
1.2
1.2
—
—
—
0
0
388
3422
1.16
1.89
2.1
2.0
—
—
—
0
0
82
611
1.35
1.87
1.5
1.4
18.4
20.6
u/l
0.28
68
528
8
28
2.86
1.86
5.6
2.3
—
—
—
0
0
16
79
2.03
1.85
1.3
1.5
9822.5
36607.3
e6/l
—
8
46
148
1200
1.25
1.81
1.1
1.1
—
—
—
0
0
51
352
1.46
1.81
3.5
2.9
1.9
2.1
mmol/l
0.32
29
208
8
29
2.76
1.79
6.4
8.6
—
—
—
0
0
51
354
1.45
1.76
1.8
1.7
9307.3
10971.4
e6/l
0.15
35
258
86
653
1.33
1.76
1.1
1.1
3.3
6.5
u/ml
2.98
45
357
43
289
1.50
1.74
3.6
3.3
39.3
41.0
mg/l
0.04
37
231
82
619
1.34
1.74
1.1
1.1
1.1
0.9
u/ml
0.17
37
269
21
117
1.80
1.74
1.2
1.5
1.4
3.5
nmol/l
0.61
16
91
65
474
1.38
1.72
1.2
1.1
—
—
—
0
0
50
348
1.45
1.71
2.9
2.5
—
—
—
0
0
24
141
1.71
1.68
1.4
1.4
—
—
—
0
0
180
1508
1.21
1.64
9.7
8.2
0.3
0.8
mmol/l
1.33
144
1158
19
105
1.82
1.63
1.2
1.2
—
—
—
0
0
842
7865
1.10
1.59
1.7
1.7
—
—
—
0
0
42
289
1.46
1.55
3.6
3.3
27.9
60.3
mg/l
0.84
35
230
21
124
1.70
1.47
1.2
1.1
—
—
—
0
0
9
38
2.37
1.45
1.1
1.1
—
—
—
0
0
20
117
1.71
1.45
1.7
2.2
11.1
11.1
%
0.00
20
117
5
16
3.13
1.44
1.0
1.3
—
—
—
0
0
178
1513
1.19
1.42
9.7
8.1
13.0
13.3
kpa
0.20
166
1447
178
1513
1.19
1.42
9.8
8.1
5.0
5.1
kpa
0.37
165
1445
135
1118
1.22
1.41
1.4
1.3
8.0
9.3
u/l
0.78
107
942
34
229
1.49
1.41
2.2
3.1
1.3
1.5
%
0.13
26
188
56
415
1.36
1.39
4.3
2.9
7.4
7.4
ph
0.09
49
348
2046
19992
1.11
1.36
3.4
3.1
1.2
1.2
mmol/l
0.22
1899
18985
26
167
1.56
1.34
1.0
1.1
—
—
—
0
0
16
90
1.78
1.33
1.4
1.4
1174.4
2655.4
e6/l
—
9
61
66
506
1.31
1.32
1.1
1.1
2.1
3.9
u/ml
1.10
20
200
155
1313
1.19
1.30
2.5
2.3
—
—
—
0
0
13
69
1.89
1.28
1.8
2.2
17.7
14.7
umol/l
0.50
13
69
58
439
1.33
1.28
4.1
4.0
56.9
56.8
%
0.02
58
439
12
62
1.94
1.27
1.3
1.0
—
—
—
0
0
24
154
1.56
1.25
3.1
3.4
—
—
—
0
0
57
432
1.33
1.25
3.8
3.7
3.6
4.0
e9/l
0.85
57
432
15
85
1.77
1.23
1.3
1.2
—
—
—
0
0
31
212
1.47
1.23
1.4
1.3
—
—
—
0
0
39
279
1.40
1.22
1.7
1.6
—
—
—
0
0
59
454
1.31
1.18
1.1
1.0
0.0
0.3
u/ml
—
10
98
28
190
1.48
1.16
1.6
1.2
0.7
0.4
u/ml
0.29
14
63
258
2298
1.14
1.15
1.4
1.4
—
—
—
0
0
540
5798
0.91
1.11
4.1
3.4
0.0
0.0
estimate
0.27
201
2190
27
184
1.47
1.10
1.1
1.1
—
—
—
0
0
391
3580
1.11
1.10
1.6
1.6
17417859.3
42172945.4
pmol/l
0.63
333
3130
502
4661
1.10
1.07
3.6
3.3
1.0
1.0
kg/l
0.16
73
685
7
33
2.12
1.05
3.0
1.7
—
—
—
0
0
26
178
1.47
1.05
1.3
1.6
2.0
1.3
promille
1.41
21
141
59
463
1.28
1.05
1.2
1.2
—
—
—
0
0
53
410
1.30
1.05
1.1
1.2
—
—
—
0
0
87
715
1.22
1.04
1.2
1.1
1.7
1.5
u/ml
0.06
30
294
45
341
1.33
1.03
1.5
1.4
—
—
—
0
0
50
642
0.77
1.01
7.2
7.9
—
—
—
0
0
5
108
0.46
1.00
1.2
1.1
—
—
—
0
0
87
719
1.22
1.00
14.3
11.2
—
—
—
0
0
35
471
0.74
0.99
2.8
4.1
1.3
1.4
mmol/l
0.25
35
462
17
107
1.59
0.99
2.6
3.0
8.5
7.0
mg/l
0.29
12
90
5
23
2.18
0.98
3.2
4.4
—
—
—
0
0
10
54
1.86
0.96
1.1
1.7
—
—
—
0
0
10
54
1.86
0.96
1.4
1.0
—
—
—
0
0
10
54
1.86
0.96
1.4
1.0
—
—
—
0
0
10
54
1.86
0.96
1.4
1.0
—
—
—
0
0
141
1222
1.16
0.96
3.8
4.2
5.6
47.2
ug/l
0.81
109
913
28
387
0.72
0.95
3.1
3.1
16.5
23.3
mg/l
1.04
14
237
14
85
1.65
0.94
1.5
1.7
—
—
—
0
0
77
634
1.22
0.93
1.1
1.1
0.3
1.7
u/ml
4.74
14
154
226
2031
1.12
0.92
1.3
1.3
—
—
—
0
0
225
2023
1.12
0.91
1.6
1.6
—
—
—
0
0
14
86
1.63
0.91
1.4
1.4
—
—
—
0
0
47
367
1.29
0.90
1.3
1.3
—
—
—
0
0
21
143
1.47
0.89
2.1
2.8
46.0
54.7
%
0.95
14
100
8
42
1.91
0.88
1.0
1.5
—
—
—
0
0
98
832
1.18
0.88
10.9
10.2
94.0
94.3
%
0.19
98
827
16
103
1.56
0.87
1.1
1.3
188.0
350.4
u/l
0.81
16
91
15
95
1.58
0.87
1.1
1.6
—
—
—
0
0
14
88
1.59
0.84
1.0
1.1
—
—
—
0
0
8
45
1.78
0.84
1.1
1.0
113.7
72.8
ug/l
—
8
40
25
179
1.40
0.84
2.0
1.4
0.9
1.0
g/l
0.22
25
179
18
121
1.49
0.82
1.3
1.6
—
2130.8
—
0
20
21
146
1.44
0.82
1.4
1.4
—
—
—
0
0
12
73
1.65
0.81
1.6
2.1
—
—
—
0
0
14
89
1.58
0.81
1.4
1.5
—
—
—
0
0
56
454
1.24
0.81
4.0
3.7
66.5
2790.3
u/ml
0.67
48
390
22
155
1.42
0.81
1.7
1.3
1.6
1.5
nmol/l
0.18
17
142
32
241
1.33
0.80
1.5
1.4
—
—
—
0
0
6
33
1.82
0.79
2.0
2.0
—
—
—
0
0
180
1619
1.12
0.75
4.9
4.4
1.2
0.9
%
0.44
48
393
67
560
1.20
0.74
1.1
1.0
2.1
3.9
u/ml
0.98
21
213
27
202
1.34
0.72
1.1
1.0
—
—
—
0
0
77
654
1.18
0.72
1.5
1.4
68.6
101.0
pmol/l
0.58
77
638
172
1548
1.12
0.72
5.0
4.4
0.1
0.2
%
1.27
43
367
7
40
1.75
0.71
1.4
1.3
—
—
—
0
0
9
143
0.63
0.69
3.0
2.3
107.2
105.9
mmol/l
—
9
143
9
143
0.63
0.69
3.0
2.3
3.9
4.0
mmol/l
—
9
143
50
409
1.23
0.69
2.6
2.7
—
—
—
0
0
165
1488
1.12
0.68
5.0
4.5
0.0
0.3
%
0.74
41
312
85
736
1.16
0.65
1.4
1.5
0.5
0.5
nmol/l
0.16
75
607
11
70
1.57
0.65
1.1
1.1
—
—
—
0
0
672
6436
1.06
0.64
3.2
2.7
—
—
—
0
0
16
112
1.43
0.63
1.6
2.0
0.2
2.0
u/field
—
5
61
18
129
1.40
0.63
1.4
1.2
—
—
—
0
0
20
147
1.36
0.61
1.1
1.2
—
—
—
0
0
5
30
1.67
0.61
1.4
1.7
9.3
12.2
g/l
—
5
22
9
139
0.65
0.60
3.0
2.3
—
—
—
0
0
17
122
1.40
0.60
1.2
1.4
—
—
—
0
0
92
809
1.14
0.59
3.2
2.7
—
—
—
0
0
10
64
1.56
0.58
1.2
1.1
—
—
—
0
0
10
64
1.56
0.58
1.0
1.0
—
—
—
0
0
13
185
0.70
0.58
1.2
1.2
—
—
—
0
0
24
184
1.31
0.57
1.9
1.7
50.8
55.8
%
0.26
16
115
23
176
1.31
0.56
4.1
2.8
—
—
—
0
0
8
55
1.46
0.56
1.1
1.1
—
—
—
0
0
14
99
1.42
0.54
1.1
1.6
145.8
138.6
nmol/l
0.14
14
99
119
1319
0.90
0.54
5.2
3.0
1.2
1.2
mmol/l
0.50
105
1138
9
63
1.43
0.52
5.2
4.8
—
—
—
0
0
71
810
0.87
0.51
10.1
7.6
24.7
24.2
mmol/l
0.73
64
749
18
135
1.34
0.51
1.2
1.5
—
—
—
0
0
13
92
1.42
0.50
1.2
1.2
—
—
—
0
0
39
325
1.20
0.49
4.4
3.1
31.1
33.5
umol/l
0.34
31
283
14
101
1.39
0.49
2.4
2.2
—
—
—
0
0
23
181
1.27
0.48
2.6
1.6
6.3
5.9
mmol/l
0.35
23
141
19
146
1.30
0.47
1.1
1.1
1533.1
1519.8
miu/ml
0.02
19
146
72
813
0.88
0.46
9.0
5.5
—
—
—
0
0
22
174
1.27
0.45
8.5
6.0
10.5
10.4
mg/l
0.02
22
161
93
838
1.11
0.44
11.2
10.0
1.3
1.4
%
0.23
93
832
163
1511
1.08
0.44
5.0
4.1
0.6
0.6
%
0.12
41
299
24
193
1.25
0.43
1.4
1.5
51.8
69.8
mmol/l
1.95
19
162
191
2041
0.93
0.42
4.4
3.2
—
—
—
0
0
93
842
1.11
0.41
11.3
10.0
0.7
0.7
%
0.32
93
837
27
222
1.22
0.41
2.3
2.0
—
—
—
0
0
40
342
1.17
0.41
2.6
2.6
93.3
115.0
ug/min
0.11
22
226
0
17
0.00
0.40
0.0
1.0
—
0.1
—
0
9
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
21
168
1.25
0.40
1.3
1.2
—
—
—
0
0
90
816
1.11
0.40
3.0
2.5
0.2
0.2
e6/l
0.18
84
781
5
35
1.43
0.39
2.4
2.2
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
150
1397
1.08
0.38
3.6
3.2
—
—
—
0
0
142
1320
1.08
0.37
11.5
8.8
95.9
96.3
%
0.29
136
1269
22
179
1.23
0.37
1.2
1.6
301.4
283.1
mosm/kgh2o
1.57
17
143
60
535
1.12
0.36
1.4
1.3
—
—
—
0
0
75
679
1.11
0.35
1.6
2.1
2.1
4.6
iu/l
4.17
22
286
33
283
1.17
0.34
1.5
1.6
—
—
—
0
0
6
46
1.31
0.33
3.2
1.7
—
—
—
0
0
6
46
1.31
0.33
5.0
2.2
—
—
—
0
0
30
258
1.16
0.31
1.0
1.1
—
—
—
0
0
31
268
1.16
0.30
3.6
4.2
208.9
80.5
u/ml
—
8
80
10
76
1.32
0.28
1.9
1.4
—
—
—
0
0
8
62
1.29
0.28
1.5
1.2
—
—
—
0
0
27
311
0.87
0.27
1.3
1.5
15.2
12.2
mmol/l
—
8
47
18
215
0.84
0.27
1.6
1.5
—
—
—
0
0
26
224
1.16
0.27
1.2
1.0
0.9
0.4
u/ml
—
6
56
132
1247
1.06
0.26
12.1
9.2
120.9
123.4
g/l
0.76
127
1195
21
179
1.17
0.25
1.1
1.3
—
—
—
0
0
21
179
1.17
0.25
2.5
3.2
—
—
—
0
0
17
142
1.20
0.24
2.8
2.9
—
—
—
0
0
26
227
1.15
0.23
3.9
3.5
—
—
—
0
0
30
337
0.89
0.22
4.1
3.3
—
—
—
0
0
17
144
1.18
0.22
1.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
4.6
—
0
11
0
10
0.00
0.21
0.0
1.1
—
41.1
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.3
—
3.9
—
0
5
0
14
0.00
0.20
0.0
7.1
—
—
—
0
0
9
114
0.79
0.20
1.4
1.2
—
—
—
0
0
36
327
1.10
0.19
2.7
2.3
—
—
—
0
0
11
90
1.22
0.19
2.6
2.3
—
—
—
0
0
7
58
1.21
0.18
1.1
1.2
—
—
—
0
0
7
60
1.17
0.17
1.1
3.4
—
—
—
0
0
23
205
1.12
0.17
1.1
1.3
—
—
—
0
0
7
90
0.78
0.14
4.3
2.6
2135.7
2031.0
ml
—
7
83
54
509
1.06
0.14
4.3
4.6
—
—
—
0
0
12
104
1.15
0.12
2.5
2.3
—
—
—
0
0
14
158
0.89
0.12
1.1
1.1
—
—
—
0
0
45
476
0.94
0.11
2.0
2.0
2.0
2.0
ug/l
0.01
39
427
44
465
0.95
0.11
13.3
6.5
1.2
1.2
mmol/l
0.01
38
393
562
5556
1.01
0.10
4.4
4.1
—
—
—
0
0
5
47
1.06
0.09
1.0
1.2
—
—
—
0
0
23
215
1.07
0.07
1.2
1.0
2.9
1.6
u/ml
—
5
69
22
207
1.06
0.06
1.8
1.5
—
—
—
0
0
22
207
1.06
0.06
1.8
1.5
—
—
—
0
0
22
207
1.06
0.06
1.8
1.5
—
—
—
0
0
22
207
1.06
0.06
1.8
1.5
—
—
—
0
0
10
90
1.11
0.05
2.0
2.6
473.8
508.3
min
—
5
69
30
289
1.04
0.04
1.2
1.4
—
—
—
0
0
13
121
1.07
0.03
1.0
1.1
—
—
—
0
0
14
139
1.01
0.00
2.1
1.3
26112.5
81792.6
e6/l
—
8
91
21
209
1.00
0.00
20.1
13.0
679.8
829.1
nmol/l
1.17
21
201
88
875
1.01
0.00
1.3
1.3
2.7
3.9
ug/l
1.61
82
822
11
108
1.02
0.00
1.8
2.5
657.0
581.0
ml
—
5
78
14
138
1.01
0.00
6.1
7.0
—
—
—
0
0
15
152
0.99
0.00
4.1
2.1
34.6
32.2
pg
0.96
15
152
0
6
0.00
0.00
0.0
1.5
—
2.6
—
0
6
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
66
0.91
0.00
2.3
3.2
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
5
49
1.02
0.00
1.0
1.1
—
—
—
0
0
6
66
0.91
0.00
4.7
6.4
—
—
—
0
0
0
8
0.00
0.00
0.0
4.5
—
—
—
0
0
7
72
0.97
0.00
1.3
3.0
—
—
—
0
0
7
69
1.01
0.00
1.3
1.7
—
—
—
0
0
7
74
0.95
0.00
1.3
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_ANOGENITAL_HERPES_SIMPLEX and mortality.

Females

Parameter HR [95% CI] p-value
AB1_ANOGENITAL_HERPES_SIMPLEX 1.478 [1.24, 1.77] < 0.001
Birth year 0.999 [0.99, 1.01] 0.774

During the follow-up period (1.1.1998 — 31.12.2019), 245 out of 9937 females with AB1_ANOGENITAL_HERPES_SIMPLEX died.

Males

Parameter HR [95% CI] p-value
AB1_ANOGENITAL_HERPES_SIMPLEX 1.04 [0.89, 1.22] 0.631
Birth year 0.987 [0.98, 1.0] 0.023

During the follow-up period (1.1.1998 — 31.12.2019), 264 out of 5301 males with AB1_ANOGENITAL_HERPES_SIMPLEX died.

Mortality risk

Mortality risk for people of age

years, who have AB1_ANOGENITAL_HERPES_SIMPLEX.

N-year risk Females Males
1 0.155% 0.245%
5 1.036% 1.155%
10 2.609% 2.958%
15 4.978% 5.608%
20 8.779% 9.633%

Relationships between endpoints

Index endpoint: AB1_ANOGENITAL_HERPES_SIMPLEX – Anogenital herpesviral [herpes simplex] infection

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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