Hypoplasia of dental enamel, prenatal

K11_HYPOPLASIA_ENAMEL_PRENATAL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K00.41
  • Cause of death: ICD-10 K00.41

2 out of 7 registries used, show all original rules.

65

4. Check minimum number of events

None

65

5. Include endpoints

None

65

6. Filter based on genotype QC (FinnGen only)

65

Control definitions (FinnGen only)

Control exclude
K11_MIH

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 444 197 247
Only index persons 110 54 56
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 4.63 4.01
Only index persons 8.81 9.75 7.90

-FinnGen-

Key figures

All Female Male
Number of individuals 65 29 36
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 4.38 5.00 3.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
57
Matched controls
572
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K00.41
ICD-10 Finland
Prenatal enamel hypoplasia
+∞
81.7
57
*
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
+∞
44.8
37
*
127
Kela drug reimbursment
Transplant complication
59.0
24.5
28
9
L04AX01
ATC
azathioprine; systemic
48.2
23.4
28
11
SAA03
NOMESCO Finland
Extended examination of mouth
109.6
22.8
56
192
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
80.4
22.3
24
5
H02AB04
ATC
methylprednisolone; systemic
44.9
22.3
27
11
Z94.0
ICD-10 Finland
Kidney transplant status
66.9
21.6
24
6
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
27.3
21.0
30
22
ZX120
NOMESCO Finland
Intravenous
19.4
20.1
34
40
R4110
NOMESCO Finland
Physiotherapy
18.5
19.3
49
141
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
24.9
19.2
28
21
A11CC03
ATC
alfacalcidol; systemic
41.4
18.8
23
9
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
+∞
18.8
17
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
20.6
18.7
51
166
H02AB09
ATC
hydrocortisone; systemic
19.1
17.8
29
29
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
59.9
17.7
20
5
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.7
17.6
38
72
WX408
NOMESCO Finland
General anesthesy, balanced
18.5
17.3
51
179
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
40.3
17.1
21
8
137
Kela drug reimbursment
Uraemia requiring dialysis
85.5
16.9
18
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
31.5
16.8
22
11
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
42.8
16.6
20
7
EBA15
NOMESCO Finland
Extraction of large number of teeth
19.7
16.6
26
23
KAC00
NOMESCO Finland
Nephrectomy
64.0
16.2
18
*
L04AA06
ATC
mycophenolic acid; systemic
32.2
16.2
21
10
K03.00
ICD-10 Finland
Approximal wear
39.6
15.5
19
7
C08CA01
ATC
amlodipine; oral
21.7
15.5
23
17
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
108.6
15.5
16
*
TPH07
NOMESCO Finland
Cathetrisation of artery
10.9
15.0
36
77
L04AD01
ATC
ciclosporin; systemic
24.7
14.9
21
13
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
19.4
14.8
23
19
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
11.7
14.8
32
56
TK800
NOMESCO Finland
Hemodialysis
72.4
14.7
16
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
10.4
14.6
43
129
K03.66
ICD-10 Finland
Tooth plaque
10.8
14.4
33
64
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
14.0
14.2
26
32
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
15.7
14.1
24
25
A12AA04
ATC
calcium carbonate; oral
54.2
14.0
16
*
B03XA01
ATC
erythropoietin; parenteral
54.2
14.0
16
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
11.2
13.6
29
48
K02.0
ICD-10 Finland
Caries limited to enamel
9.5
13.6
35
81
TPH04
NOMESCO Finland
Cathetrisation of vein
9.7
13.6
34
75
GD1AA
NOMESCO Finland
Thorax X-ray examination
9.2
13.3
42
133
Z99.2
ICD-10 Finland
Dependence on renal dialysis
90.7
13.3
14
*
TK820
NOMESCO Finland
Peritoneal dialysis
90.7
13.3
14
*
B05DA
ATC
Isotonic solutions
164.8
13.0
13
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
36.1
12.9
16
6
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
10.0
12.7
29
53
IGY02
NOMESCO Finland
Psychiatric monitoring contact
12.5
12.6
24
31
SAA04
NOMESCO Finland
Special inverstigation of mouth
17.4
12.6
20
17
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
60.5
12.5
14
*
ZX199
NOMESCO Finland
Other rote
30.9
12.4
16
7
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
8.1
12.1
37
106
205
Kela drug reimbursment
Chronic hypertension
19.5
12.0
18
13
Z49.1
ICD-10 Finland
Extracorporeal dialysis
+∞
11.9
11
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
7.7
11.7
36
103
K06.18
ICD-10 Finland
Another gingival hyperplasia
36.2
11.4
14
5
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
11.6
11.3
22
29
Z49.2
ICD-10 Finland
Other dialysis
74.4
11.1
12
*
WX110
NOMESCO Finland
Local anesthesy
9.2
11.0
49
228
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
8.0
10.9
29
65
ZXA00
NOMESCO Finland
Right side
8.7
10.8
26
50
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
14.9
10.8
18
17
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
+∞
10.7
10
*
1AB02
NOMESCO Finland
NA
22.0
10.6
15
9
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
14.0
10.5
18
18
5AB14
NOMESCO Finland
NA
66.8
10.0
11
*
SCE00
NOMESCO Finland
Fissure closure of tooth
7.0
9.9
29
73
RS220
NOMESCO Finland
NA
17.9
9.9
15
11
4AA09
NOMESCO Finland
NA
37.1
9.9
12
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
15.3
9.8
16
14
WW500
NOMESCO Finland
Blood transfusion
12.0
9.7
18
21
SFA40
NOMESCO Finland
Replacement of krone of tooth
20.1
9.6
14
9
WX882
NOMESCO Finland
High dependency care
6.1
9.4
34
111
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
29.7
9.4
12
5
602
Kela drug reimbursment
Children's severe malnutrition
8.9
9.3
21
35
RD210
NOMESCO Finland
NA
8.3
9.3
22
40
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
8.1
9.1
22
41
XF400
NOMESCO Finland
ECG with 12 standard connections
5.7
8.9
36
131
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
24.7
8.9
12
6
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
33.3
8.9
11
*
R50.9
ICD-10 Finland
Fever, unspecified
5.6
8.8
36
133
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
13.1
8.7
15
15
K02.1
ICD-10 Finland
Caries of dentine
5.5
8.5
38
152
RS121
NOMESCO Finland
NA
14.9
8.1
13
11
FM2CE
NOMESCO Finland
NA
5.7
8.0
27
77
L04AA01
ATC
[U] ciclosporin; systemic
29.7
7.9
10
*
I15.8
ICD-10 Finland
Other secondary hypertension
29.7
7.9
10
*
ZXA05
NOMESCO Finland
Left side
7.6
7.8
19
35
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
11.9
7.8
14
15
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
5.1
7.8
33
121
A41.9
ICD-10 Finland
Sepsis, unspecified
16.5
7.8
12
9
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
16.5
7.8
12
9
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
5.6
7.7
26
74
V03AE01
ATC
polystyrene sulfonate; oral
91.5
7.6
8
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
12.5
7.5
13
13
3A013
NOMESCO Finland
NA
34.9
7.4
9
*
XA800
NOMESCO Finland
Neuropsychological investigation
5.4
7.3
25
72
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
13.4
7.2
12
11
ZXA10
NOMESCO Finland
Bilateral
5.3
7.0
24
68
N18.8
ICD-10 Finland
Other chronic renal failure
19.8
7.0
10
6
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.6
7.0
22
57
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
45.6
6.9
8
*
XF602
NOMESCO Finland
Bloodpressure monitoring
26.2
6.9
9
*
SAB03
NOMESCO Finland
Oral health check
0.2
6.8
22
420
XX4AW
NOMESCO Finland
NA
8.1
6.7
15
24
JAF10
NOMESCO Finland
Repair of umbilical hernia
78.3
6.6
7
*
TK823
NOMESCO Finland
Peritoneal permeability analysis
78.3
6.6
7
*
783
NOMESCO Finland
NA
30.4
6.4
8
*
C07AB02
ATC
metoprolol; systemic
14.8
6.4
10
8
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.4
6.3
27
96
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
9.8
6.2
12
15
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
17.4
6.1
9
6
IEP02
NOMESCO Finland
Child-centred family therapy
6.3
6.0
16
33
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
5.9
6.0
17
38
UDC00
NOMESCO Finland
Ear microscopy
7.4
6.0
14
24

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
28
28
16.81
26.70
2.7
2.1
—
—
—
0
0
31
37
15.11
26.39
5.8
2.2
—
—
—
0
0
46
109
12.02
22.45
55.1
12.1
0.7
0.8
mmol/l
5.70
46
104
44
101
11.39
21.99
61.1
18.4
1.4
1.0
mg/l
4.24
44
101
27
34
12.87
21.77
2.3
1.9
—
—
—
0
0
51
144
12.80
20.98
10.6
3.8
—
—
—
0
0
29
44
11.09
20.24
5.3
2.2
147.7
103.2
u/ml
0.50
18
14
48
133
10.98
19.80
9.4
3.7
—
—
—
0
0
39
89
9.46
19.11
20.6
8.2
5.4
6.6
umol/l
0.37
31
68
23
8
43.30
19.04
3.2
2.6
—
—
—
0
0
43
110
9.60
18.92
9.1
3.7
—
—
—
0
0
47
134
10.05
18.60
16.3
5.9
32.1
31.1
s
0.26
47
134
51
167
10.54
17.36
10.6
4.4
—
—
—
0
0
32
65
8.73
17.16
5.2
2.0
—
—
—
0
0
56
213
12.72
16.49
55.4
8.8
1.4
1.5
mmol/l
1.00
56
204
30
60
8.43
16.20
3.1
1.9
—
—
—
0
0
17
17
13.19
15.61
5.4
3.9
—
—
—
0
0
17
17
13.19
15.61
5.4
4.3
—
—
—
0
0
19
25
10.33
14.38
8.4
6.8
0.0
1.4
%
—
12
7
14
12
14.59
14.00
1.1
1.3
721.2
585.2
pmol/l
0.56
14
12
19
28
9.18
13.09
9.3
6.7
0.1
0.8
%
0.76
14
11
24
47
7.51
12.91
2.2
1.4
—
—
—
0
0
53
222
8.52
12.71
37.7
10.7
—
—
—
0
0
35
101
6.34
12.66
15.3
3.3
7.4
7.4
ph
—
6
11
18
26
9.19
12.57
8.9
7.0
0.0
0.0
%
—
12
9
19
32
7.98
11.61
6.6
3.2
—
—
—
0
0
21
40
7.28
11.48
1.8
1.4
—
—
—
0
0
26
62
6.32
11.37
2.5
1.7
—
—
—
0
0
22
45
6.88
11.22
1.7
1.7
—
—
—
0
0
43
163
5.84
11.07
9.9
3.5
1.2
1.2
mmol/l
0.09
43
156
35
112
5.60
10.99
6.9
2.3
—
—
—
0
0
19
34
7.48
10.96
3.5
2.1
—
—
—
0
0
19
34
7.48
10.96
3.5
2.1
—
—
—
0
0
19
34
7.48
10.96
3.5
2.1
—
—
—
0
0
19
34
7.48
10.96
3.5
2.1
—
—
—
0
0
52
234
7.11
10.89
50.9
9.6
5.5
5.7
kpa
1.10
52
227
14
7
24.93
10.33
3.0
2.3
—
—
—
0
0
14
7
24.93
10.33
1.4
1.1
—
—
—
0
0
26
68
5.71
10.17
2.3
1.8
—
—
—
0
0
50
229
6.13
9.91
47.9
9.5
5.5
5.5
kpa
0.04
50
222
17
30
7.32
9.86
25.1
23.0
0.7
0.7
%
0.00
17
30
19
38
6.65
9.80
44.1
19.7
117.6
123.2
g/l
0.44
19
38
48
214
5.75
9.79
11.3
3.7
74.0
50.0
ug/l
0.69
48
206
56
301
7.20
9.69
34.4
9.0
—
—
—
0
0
52
252
6.32
9.47
48.4
9.6
—
—
—
0
0
42
172
5.07
9.42
10.2
3.3
2.4
2.5
mmol/l
0.26
42
163
42
172
5.07
9.42
10.1
3.3
1.4
1.3
mmol/l
0.09
42
161
17
32
6.84
9.25
25.1
21.7
1.1
1.2
%
0.03
17
32
12
15
9.58
9.17
14.2
7.0
9.2
10.3
mg/l
0.15
12
15
53
271
6.18
8.76
24.6
4.4
207.8
201.6
u/l
0.15
53
260
13
9
17.63
8.63
3.1
2.4
—
—
—
0
0
13
9
17.63
8.63
1.5
1.2
—
—
—
0
0
14
23
7.48
8.58
3.3
4.5
21.6
29.1
umol/l
0.88
14
23
31
108
4.58
8.37
3.8
1.6
—
—
—
0
0
21
54
5.27
8.20
1.7
1.9
—
—
—
0
0
50
252
5.26
8.19
22.9
4.5
—
—
—
0
0
13
21
7.49
8.05
16.7
4.5
—
—
—
0
0
34
131
4.35
7.95
6.9
2.7
2.4
2.4
mmol/l
0.39
34
119
11
6
21.63
7.91
6.2
2.0
—
—
—
0
0
10
13
8.91
7.33
2.0
1.2
—
—
—
0
0
10
13
8.91
7.33
18.7
6.8
—
—
—
0
0
58
374
6.10
6.97
95.5
16.4
1.2
1.2
mmol/l
0.55
58
363
12
22
6.46
6.56
2.4
3.0
26.8
31.5
mmol/l
0.24
12
22
16
39
5.12
6.53
6.5
4.2
72.9
65.4
%
0.56
16
39
9
5
20.52
6.46
24.8
12.4
—
—
—
0
0
58
380
5.88
6.45
104.8
14.0
1.2
1.2
mmol/l
0.31
58
365
51
291
4.49
6.37
63.0
14.1
24.5
24.4
mmol/l
0.02
51
291
39
187
3.71
6.29
17.0
4.1
2.7
0.5
e6/l
0.69
34
123
13
27
5.77
6.28
36.1
6.5
23.9
23.3
mmol/l
0.20
13
27
57
377
5.15
6.05
40.6
10.0
—
—
—
0
0
12
24
5.91
6.01
34.7
25.9
78.1
75.8
%
0.30
12
24
32
140
3.53
5.86
5.2
4.1
3.2
2.6
mg/l
0.95
32
131
20
64
4.07
5.78
22.0
4.9
—
—
—
0
0
60
430
6.13
5.39
55.2
11.1
0.0
0.0
e9/l
0.50
52
302
37
185
3.32
5.35
11.4
3.2
—
—
—
0
0
11
23
5.55
5.23
1.5
1.2
—
—
—
0
0
10
20
5.73
4.95
37.3
30.6
11.8
11.7
%
—
10
20
10
20
5.73
4.95
4.4
2.5
—
—
—
0
0
35
176
3.14
4.90
13.7
3.3
—
—
—
0
0
12
29
4.85
4.86
4.3
3.9
—
—
—
0
0
11
25
5.09
4.77
37.1
26.2
—
—
—
0
0
32
157
3.04
4.62
2.3
1.5
—
—
—
0
0
9
13
7.83
4.32
2.3
2.8
13.5
11.4
umol/l
—
9
13
13
37
4.14
4.30
7.5
4.3
—
—
—
0
0
8
10
8.93
4.19
2.5
2.5
1.0
1.1
umol/l
—
8
10
8
10
8.93
4.19
5.8
11.6
—
—
—
0
0
36
198
2.83
4.10
10.3
3.7
32.9
36.7
mmol/mol
3.06
36
185
11
29
4.36
3.99
3.5
3.8
—
—
—
0
0
8
11
8.10
3.99
1.0
1.5
—
—
—
0
0
40
237
2.79
3.88
28.5
5.3
0.0
0.0
estimate
0.00
13
24
40
237
2.79
3.88
18.9
3.2
0.0
0.0
estimate
0.00
11
22
51
344
3.24
3.87
28.3
4.3
—
—
—
0
0
6
5
13.01
3.84
24.2
2.0
—
—
—
0
0
40
238
2.77
3.83
19.0
3.2
0.0
0.0
estimate
0.00
13
24
17
65
3.19
3.65
2.6
1.3
—
—
—
0
0
6
6
10.84
3.57
9.0
2.3
3.0
2.3
e9/l
—
6
6
6
6
10.84
3.57
2.3
2.5
—
—
—
0
0
6
7
9.28
3.33
1.5
3.7
—
—
—
0
0
6
7
9.28
3.33
9.8
2.4
43.8
40.9
%
—
6
7
12
39
3.55
3.28
7.0
4.2
29.8
23.6
%
1.02
12
39
10
29
3.89
3.19
11.3
26.7
—
—
—
0
0
13
46
3.28
3.13
2.8
2.5
3.2
2.9
u/l
—
6
21
6
8
8.11
3.12
26.5
6.3
4.7
4.5
kpa
—
6
8
6
8
8.11
3.12
2.8
1.9
—
—
—
0
0
6
8
8.11
3.12
26.5
6.4
11.0
8.7
kpa
—
6
8
17
71
2.89
3.12
18.5
2.3
—
—
—
0
0
7
12
6.38
3.11
10.1
2.2
1.7
1.5
mmol/l
—
7
12
5
5
10.67
3.03
1.2
1.2
—
—
—
0
0
48
336
2.64
2.99
22.5
4.0
9.4
9.1
mm/h
0.10
48
320
7
13
5.89
2.95
2.3
1.3
—
—
—
0
0
6
9
7.20
2.93
1.7
1.2
—
—
—
0
0
8
18
4.91
2.90
1.3
1.5
—
—
—
0
0
5
6
8.89
2.79
1.0
1.0
—
—
—
0
0
5
6
8.89
2.79
1.0
1.0
—
—
—
0
0
10
32
3.51
2.78
11.4
26.5
1.0
0.9
%
—
10
32
10
32
3.51
2.78
11.4
26.5
0.8
0.7
%
—
10
32
10
32
3.51
2.78
11.4
26.6
94.9
94.0
%
—
10
32
6
10
6.48
2.76
10.7
2.2
66.2
76.4
mg/l
—
6
10
20
97
2.53
2.74
18.0
2.5
0.0
0.0
estimate
0.00
11
25
6
11
5.88
2.60
1.0
1.2
—
—
—
0
0
6
11
5.88
2.60
1.0
1.0
—
—
—
0
0
6
12
5.38
2.46
5.8
1.0
—
—
—
0
0
8
22
3.99
2.45
18.4
3.1
—
—
—
0
0
10
35
3.19
2.42
11.4
23.7
23.2
24.1
mmol/l
—
10
35
5
8
6.65
2.41
1.2
1.1
—
—
—
0
0
0
61
0.00
2.39
0.0
1.2
—
10.9
—
0
46
5
9
5.91
2.25
1.0
1.3
—
—
—
0
0
0
58
0.00
2.17
0.0
1.2
—
8.0
—
0
41
9
31
3.20
2.17
6.1
2.9
—
—
—
0
0
7
20
3.79
2.12
2.0
1.5
—
—
—
0
0
6
15
4.29
2.09
1.3
1.5
—
—
—
0
0
11
45
2.74
2.05
3.2
2.5
5.1
8.7
iu/l
—
6
24
6
19
3.37
1.70
3.0
3.6
—
—
—
0
0
10
45
2.44
1.55
6.0
5.0
—
—
—
0
0
10
45
2.44
1.55
6.2
5.0
—
—
—
0
0
5
15
3.52
1.55
5.0
4.9
28.9
24.2
ug/l
—
5
15
5
16
3.29
1.46
4.0
1.7
—
—
—
0
0
30
214
1.75
1.35
2.4
2.2
—
—
—
0
0
8
34
2.54
1.35
4.5
6.4
3.9
2.6
ug/l
—
8
34
15
87
1.94
1.29
4.1
2.5
114.1
581.9
u/l
0.89
15
87
6
25
2.54
1.27
2.2
1.2
—
—
—
0
0
9
48
2.01
1.06
6.8
4.9
1202.2
373.3
mg/l
—
9
48
9
151
0.53
1.06
1.3
1.2
—
—
—
0
0
65
622
+∞
1.00
117.6
18.3
84.5
82.7
fl
2.09
65
617
0
30
0.00
1.00
0.0
1.5
—
—
—
0
0
6
30
2.10
0.89
4.2
3.4
2045.4
12.7
mg/mmol
—
6
18
6
32
1.96
0.84
5.8
4.3
—
—
—
0
0
65
624
+∞
0.80
117.7
18.3
7.6
7.7
e9/l
0.10
65
585
65
623
+∞
0.79
117.6
18.3
4.2
4.5
e12/l
5.64
65
583
65
623
+∞
0.79
117.6
18.3
28.4
27.9
pg
1.60
65
618
65
623
+∞
0.79
117.6
18.5
286.9
289.7
e9/l
0.09
65
586
65
623
+∞
0.79
119.4
19.3
117.6
125.9
g/l
4.61
65
618
5
24
2.17
0.76
3.6
1.4
—
—
—
0
0
37
307
1.48
0.76
3.2
1.8
1.6
1.1
g/l
1.30
29
124
7
41
1.79
0.72
1.0
1.0
172.6
162.7
g/l
—
7
41
0
19
0.00
0.61
0.0
1.0
—
—
—
0
0
6
39
1.59
0.54
2.8
1.5
—
—
—
0
0
5
31
1.66
0.44
1.2
1.3
—
—
—
0
0
5
32
1.61
0.43
1.2
1.3
—
—
—
0
0
11
87
1.32
0.26
1.0
1.0
20.1
19.3
mmol/l
0.36
11
87
18
153
1.24
0.26
4.9
1.8
—
—
—
0
0
11
88
1.30
0.24
1.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
38
364
1.11
0.10
3.9
3.1
14.3
14.5
pmol/l
0.22
38
348
0
6
0.00
0.00
0.0
1.0
—
157.8
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
1221.8
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
6.0
—
0
8
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_HYPOPLASIA_ENAMEL_PRENATAL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_HYPOPLASIA_ENAMEL_PRENATAL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_HYPOPLASIA_ENAMEL_PRENATAL – Hypoplasia of dental enamel, prenatal

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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