Hypoplasia of dental enamel, prenatal

K11_HYPOPLASIA_ENAMEL_PRENATAL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K00.41
  • Cause of death: ICD-10 K00.41

2 out of 7 registries used, show all original rules.

68

4. Check minimum number of events

None

68

5. Include endpoints

None

68

6. Filter based on genotype QC (FinnGen only)

63

Control definitions (FinnGen only)

Control exclude
K11_MIH

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 444 197 247
Only index persons 110 54 56
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 4.63 4.01
Only index persons 8.81 9.75 7.90

-FinnGen-

Key figures

All Female Male
Number of individuals 63 27 36
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 4.36 5.00 3.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
68
Matched controls
680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K00.41
ICD-10 Finland
Prenatal enamel hypoplasia
+∞
97.7
68
*
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
+∞
57.7
47
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
23.7
36.8
33
26
ZX120
NOMESCO Finland
Intravenous
19.6
34.9
37
39
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
20.7
32.1
30
25
H02AB09
ATC
hydrocortisone; systemic
17.4
30.6
33
35
ZXD05
NOMESCO Finland
Urgent procedure
15.9
30.6
46
79
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
15.0
29.6
44
74
L04AX01
ATC
azathioprine; systemic
92.2
29.3
31
6
127
Kela drug reimbursment
Transplant complication
73.2
29.1
32
8
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
18.0
28.9
29
27
EBA15
NOMESCO Finland
Extraction of multiple teeth
16.1
27.0
29
30
Z94.0
ICD-10 Finland
Kidney transplant status
145.7
27.0
27
*
TPH07
NOMESCO Finland
Cathetrisation of artery
12.8
26.2
42
76
L04AD02
ATC
tacrolimus; systemic
77.2
25.8
28
6
H02AB04
ATC
methylprednisolone; systemic
45.9
25.6
31
12
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
15.2
25.4
28
30
A11CC03
ATC
alfacalcidol; systemic
66.1
25.1
28
7
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
34.2
25.1
33
18
ZXE20
NOMESCO Finland
More than three and less than five hours
12.0
24.5
38
65
SAA03
NOMESCO Finland
Extended examination of mouth
55.5
23.3
66
253
Z2221
NOMESCO Finland
Medical doctor
12.5
22.9
51
132
K03.00
ICD-10 Finland
Approximal wear
27.3
22.1
31
20
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
159.1
22.0
22
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
72.3
21.9
24
5
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
10.9
21.8
33
54
WX408
NOMESCO Finland
General anesthesy, balanced
15.5
21.2
58
185
L04AA06
ATC
mycophenolic acid; systemic
48.2
21.1
25
8
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
+∞
20.9
19
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
10.1
20.9
45
110
TPH04
NOMESCO Finland
Cathetrisation of vein
9.8
20.7
39
82
WX404
NOMESCO Finland
Intravenous generell anesthesy
13.5
20.7
56
175
Z2446
NOMESCO Finland
Social worker
10.6
20.6
49
133
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
79.6
20.4
22
*
KAC00
NOMESCO Finland
Nephrectomy
138.7
19.8
20
*
ZXE10
NOMESCO Finland
More than one and less than three hours
10.6
19.6
51
150
137
Kela drug reimbursment
Uraemia requiring dialysis
258.4
19.6
19
*
K03.66
ICD-10 Finland
Tooth plaque
9.0
19.1
40
93
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
9.4
19.1
33
62
R4110
NOMESCO Finland
Physiotherapy
13.1
19.1
57
193
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
10.5
19.0
27
40
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
92.5
18.9
20
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
9.8
18.6
50
150
IGY02
NOMESCO Finland
Psychiatric monitoring contact
9.8
18.6
29
48
L04AD01
ATC
ciclosporin; systemic
32.7
18.5
24
11
Z3226
NOMESCO Finland
Physiotherapist
10.1
18.3
52
165
Z2445
NOMESCO Finland
Psychologist
8.9
17.9
32
62
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
8.4
17.7
37
85
TK800
NOMESCO Finland
Hemodialysis
222.4
17.3
17
*
C08CA01
ATC
amlodipine; oral
18.6
17.1
27
23
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
31.6
16.9
22
10
GD1AA
NOMESCO Finland
Thorax X-ray examination
8.9
16.8
50
162
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
7.9
16.8
37
89
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
111.1
16.4
17
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
+∞
16.3
15
*
B03XA01
ATC
erythropoietin; parenteral
59.8
16.0
18
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
9.1
16.0
25
41
ZXD10
NOMESCO Finland
Scheduled procedure
10.2
15.6
56
214
A12AA04
ATC
calcium carbonate; oral
47.9
15.3
18
5
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
7.3
15.3
35
86
Z01.0
ICD-10 Finland
Examination of eyes and vision
7.3
15.2
43
130
B05DA
ATC
Isotonic solutions
+∞
15.2
14
*
TK820
NOMESCO Finland
Peritoneal dialysis
189.0
15.1
15
*
FM2CE, ,
NOMESCO Finland
7.5
14.7
29
61
602
Kela drug reimbursment
Children's severe malnutrition
9.1
14.7
22
34
RD210, ,
NOMESCO Finland
9.1
14.7
22
34
ZXA00
NOMESCO Finland
Right side
7.8
14.6
27
53
ZXE30
NOMESCO Finland
More than five and less than seven hours
8.8
14.3
22
35
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
94.4
14.2
15
*
XF400
NOMESCO Finland
ECG with 12 standard connections
6.8
14.1
42
131
Z49.1
ICD-10 Finland
Extracorporeal dialysis
+∞
14.0
13
*
Z49.2
ICD-10 Finland
Other dialysis
+∞
14.0
13
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
51.3
13.9
16
*
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
29.9
13.8
18
8
WX882
NOMESCO Finland
High dependency care
6.4
13.4
40
124
ZXE00
NOMESCO Finland
One hour or less
8.7
13.3
56
237
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
86.6
13.1
14
*
205
Kela drug reimbursment
Chronic hypertension
19.7
12.7
19
13
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
17.1
12.7
20
16
Z3231
NOMESCO Finland
Registered nurse
7.7
12.1
55
241
4AA09, ,
NOMESCO Finland
79.0
12.1
13
*
WW500
NOMESCO Finland
Blood transfusion
15.2
12.1
20
18
SCE00
NOMESCO Finland
Fissure sealant
5.9
11.8
32
89
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
143.3
11.8
12
*
1AB02, ,
NOMESCO Finland
25.6
11.8
16
8
K06.18
ICD-10 Finland
Another gingival hyperplasia
31.4
11.7
15
6
SAA04
NOMESCO Finland
Special examination of mouth
13.0
11.2
20
21
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
10.7
11.0
22
29
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
14.8
10.9
18
16
XA800
NOMESCO Finland
Neuropsychological investigation
5.9
10.7
26
65
ZX199
NOMESCO Finland
Other rote
18.5
10.6
16
11
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
6.3
10.4
22
48
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
6.9
10.3
19
36
5AB14, ,
NOMESCO Finland
64.5
10.0
11
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
11.8
9.8
18
20
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
26.3
9.8
13
6
K07.24
ICD-10 Finland
Open bite
17.1
9.7
15
11
L04AA01
ATC
[U] ciclosporin
115.4
9.7
10
*
3A013, ,
NOMESCO Finland
115.4
9.7
10
*
K02.0
ICD-10 Finland
Caries limited to enamel
4.9
9.6
42
168
WX402
NOMESCO Finland
General anaesthesia
4.9
9.3
45
194
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
9.7
9.3
19
26
WX892
NOMESCO Finland
Monitored bed care
5.5
9.2
23
58
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.8
9.1
30
96
I15.8
ICD-10 Finland
Other secondary hypertension
32.2
8.8
11
*
V03AE01
ATC
polystyrene sulfonate; oral
102.2
8.6
9
*
783, ,
NOMESCO Finland
102.2
8.6
9
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
102.2
8.6
9
*
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
20.4
8.4
12
7
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
10.6
8.4
16
19
Z3229
NOMESCO Finland
Other healthcare associate professional
4.8
8.4
25
73
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
38.4
8.3
10
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.4
8.3
32
114
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.3
8.3
36
140
WX110
NOMESCO Finland
Infiltration anesthesia
6.1
8.2
57
313
ZXA05
NOMESCO Finland
Left side
5.4
8.2
20
49
N18.8
ICD-10 Finland
Other chronic renal failure
21.5
7.9
11
6
SAB03
NOMESCO Finland
Oral health check
0.2
7.8
29
514
R50.9
ICD-10 Finland
Fever, unspecified
4.2
7.8
39
166
RS220, ,
NOMESCO Finland
10.3
7.8
15
18
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
28.8
7.8
10
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
9.1
7.7
16
22
C07AB02
ATC
metoprolol; systemic
11.4
7.7
14
15
IEP02
NOMESCO Finland
Child-centred family therapy
4.8
7.6
22
62
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
9.8
7.6
15
19
JAF10
NOMESCO Finland
Repair of umbilical hernia
89.4
7.6
8
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
10.7
7.5
14
16
XF600
NOMESCO Finland
Bloodpressure measurement
4.3
7.5
26
85
A41.9
ICD-10 Finland
Sepsis, unspecified
12.0
7.4
13
13
RS121, ,
NOMESCO Finland
12.0
7.4
13
13
K00.50
ICD-10 Finland
Dentinal dysplasia
+∞
7.4
7
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
7.4
7
*
TK823
NOMESCO Finland
Peritoneal permeability analysis
+∞
7.4
7
*
R4190
NOMESCO Finland
Nutritional therapy
4.0
7.3
35
143
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
4.0
7.3
31
117
ZXA10
NOMESCO Finland
Bilateral
4.3
7.2
25
81
SPAT1262
SPAT
Handing over of treatment supplies
8.4
7.0
15
22
V03AG01
ATC
sodium cellulose phosphate; systemic
44.6
6.9
8
*
Z94.4
ICD-10 Finland
Liver transplant status
44.6
6.9
8
*
U14
ICPC
Kidney symptom/complaint
44.6
6.9
8
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
3.9
6.9
31
121
XF602
NOMESCO Finland
Bloodpressure monitoring
25.5
6.9
9
*
UKC02
NOMESCO Finland
Cystoscopy
14.3
6.9
11
9
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
4.8
6.8
18
47
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
8.5
6.6
14
20
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.5
6.6
20
58
WW200
NOMESCO Finland
Immunization
10.9
6.6
12
13
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
10.9
6.6
12
13
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.7
6.6
32
131
Z01.8
ICD-10 Finland
Other specified special examinations
3.9
6.5
26
93
K02.1
ICD-10 Finland
Caries of dentine
3.7
6.5
43
215
KA1AE
NOMESCO Finland
Kidney ultrasound examination
20.4
6.5
9
5
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
6.1
6.3
17
35
XX4AW, ,
NOMESCO Finland
7.1
6.3
15
26
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.7
6.3
17
45
EP1AE
NOMESCO Finland
Neck ultrasound examination
9.4
6.1
12
15
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
3.9
6.1
24
84
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
7.4
6.1
14
23
K03.64
ICD-10 Finland
Dental calculus supragingival
3.6
6.0
28
110

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
32
38
15.02
27.31
6.1
2.1
—
—
—
0
0
28
29
15.71
25.99
2.7
2.1
—
—
—
0
0
28
34
13.30
23.19
2.4
1.9
—
—
—
0
0
47
111
11.47
22.88
59.1
16.4
1.36
0.99
mg/l
4.26
47
111
47
112
11.35
22.65
56.6
11.4
0.74
0.81
mmol/l
6.02
47
107
30
44
11.41
21.52
5.4
2.1
141.21
94.62
u/ml
0.54
19
13
53
151
12.38
21.51
11.2
3.8
—
—
—
0
0
41
92
9.71
20.47
25.9
8.4
6.39
6.58
umol/l
0.04
33
69
50
140
10.71
20.33
10.0
3.6
—
—
—
0
0
23
7
48.38
19.51
3.2
2.3
—
—
—
0
0
45
117
9.41
19.42
9.5
3.8
—
—
—
0
0
48
137
9.51
18.82
19.3
5.8
32.25
31.48
s
0.21
48
137
33
65
8.92
18.22
5.2
1.9
—
—
—
0
0
53
175
10.20
17.78
10.7
3.9
—
—
—
0
0
32
63
8.71
17.61
3.8
1.9
—
—
—
0
0
58
229
11.42
15.67
55.4
8.1
1.40
1.46
mmol/l
0.89
58
218
26
49
7.97
14.59
2.3
1.5
—
—
—
0
0
26
56
6.90
12.69
10.3
12.1
2907.00
1263.09
ng/l
0.81
26
51
22
40
7.65
12.60
1.8
1.4
—
—
—
0
0
23
44
7.39
12.57
1.7
1.8
—
—
—
0
0
35
103
5.94
12.22
15.3
3.3
7.39
7.41
ph
—
6
12
37
116
5.80
11.98
6.5
2.3
—
—
—
0
0
45
167
6.01
11.97
9.8
3.4
1.23
1.19
mmol/l
0.11
45
159
15
6
31.40
11.73
3.1
2.3
—
—
—
0
0
15
6
31.40
11.73
1.4
1.2
—
—
—
0
0
54
239
7.12
11.59
40.5
10.2
—
—
—
0
0
27
66
6.13
11.46
2.5
1.7
—
—
—
0
0
28
71
6.00
11.42
2.3
1.8
—
—
—
0
0
59
310
7.81
10.62
32.8
8.6
—
—
—
0
0
54
252
6.55
10.51
53.6
9.0
5.48
5.66
kpa
1.47
54
245
44
177
5.21
10.17
10.4
3.2
1.37
1.35
mmol/l
0.13
44
166
44
178
5.17
10.07
10.5
3.2
2.46
2.54
mmol/l
0.22
44
168
20
41
6.49
10.05
52.6
18.4
116.35
123.15
g/l
0.60
20
41
19
37
6.74
10.04
5.5
4.2
132.31
618.57
e6/l
3.87
13
28
17
16
13.72
9.98
5.4
4.1
—
—
—
0
0
17
16
13.72
9.98
5.4
4.1
—
—
—
0
0
14
8
21.55
9.89
1.6
1.3
—
—
—
0
0
14
8
21.55
9.89
3.1
2.5
—
—
—
0
0
49
220
5.39
9.73
11.4
3.8
73.71
48.78
ug/l
0.75
49
212
52
246
5.73
9.64
50.5
8.9
5.50
5.50
kpa
0.00
52
239
22
53
5.66
9.30
1.6
1.9
—
—
—
0
0
54
270
5.86
9.17
48.5
10.3
—
—
—
0
0
33
114
4.68
9.04
4.2
1.6
—
—
—
0
0
55
283
5.94
8.91
26.1
4.2
218.93
206.28
u/l
0.30
55
270
52
261
5.22
8.55
22.2
4.4
—
—
—
0
0
14
12
14.31
8.54
1.1
1.4
721.21
615.25
pmol/l
0.37
14
12
19
31
8.07
8.31
6.5
3.0
—
—
—
0
0
55
301
5.33
7.76
52.7
10.8
4.94
4.91
kpa
0.11
55
292
11
7
18.38
7.52
6.2
1.9
—
—
—
0
0
18
33
7.02
7.26
31.7
21.2
0.66
0.70
%
0.16
18
33
34
138
3.93
7.17
6.9
2.7
2.42
2.45
mmol/l
0.42
34
125
18
35
6.60
6.96
31.7
20.1
1.17
1.14
%
0.11
18
35
18
36
6.41
6.81
5.8
4.2
6.56
8.50
%
0.68
18
36
18
36
6.41
6.81
5.9
4.2
72.39
65.08
%
0.59
18
36
41
195
3.78
6.73
16.4
3.9
2.63
0.51
e6/l
0.67
35
128
13
16
9.75
6.70
16.1
7.0
8.86
9.98
mg/l
0.18
13
16
15
24
7.69
6.62
3.6
4.8
21.27
28.33
umol/l
0.86
15
24
9
5
20.39
6.45
24.8
12.2
—
—
—
0
0
60
399
5.27
6.39
101.0
16.7
1.23
1.24
mmol/l
0.43
60
388
60
404
5.12
6.13
108.2
14.2
1.24
1.24
mmol/l
0.17
60
389
53
311
4.19
6.10
67.1
14.7
24.53
24.36
mmol/l
0.20
53
311
63
447
6.56
6.05
55.5
10.7
0.00
0.00
e9/l
0.50
55
312
22
73
3.98
6.05
37.5
13.9
106.41
106.12
mmol/l
0.15
22
73
61
418
5.45
6.01
49.9
9.8
—
—
—
0
0
33
146
3.45
5.88
5.2
4.3
3.13
2.60
mg/l
0.92
33
137
39
197
3.30
5.51
11.1
3.2
—
—
—
0
0
13
23
6.72
5.39
16.7
4.8
—
—
—
0
0
14
28
6.01
5.30
34.8
6.3
23.79
23.36
mmol/l
0.15
14
28
13
24
6.43
5.23
2.3
3.3
26.00
33.54
mmol/l
0.45
13
24
34
165
3.12
5.04
2.4
1.5
—
—
—
0
0
10
14
8.16
4.85
2.0
1.2
—
—
—
0
0
10
14
8.16
4.85
18.7
6.6
—
—
—
0
0
13
27
5.69
4.80
43.2
23.4
77.02
76.02
%
0.12
13
27
14
34
4.91
4.53
7.0
4.3
42.24
38.15
%
0.38
14
34
11
20
6.34
4.51
4.9
2.6
—
—
—
0
0
12
25
5.59
4.44
1.5
1.2
—
—
—
0
0
13
30
5.10
4.41
4.0
4.0
—
—
—
0
0
8
9
9.88
4.41
1.0
1.1
—
—
—
0
0
14
36
4.62
4.31
6.1
4.3
28.79
23.64
%
0.90
14
36
11
22
5.75
4.22
47.0
28.3
11.50
12.02
%
0.22
11
22
37
204
2.78
4.15
10.3
3.7
32.92
36.74
mmol/mol
3.26
37
190
7
7
10.96
4.11
2.9
2.7
—
—
—
0
0
42
249
2.80
4.06
27.8
5.3
0.00
0.00
estimate
-0.00
13
26
42
249
2.80
4.06
18.4
3.2
0.00
0.00
estimate
-0.00
12
26
12
28
4.97
4.05
50.7
23.8
—
—
—
0
0
42
250
2.78
4.01
18.4
3.2
0.00
0.00
estimate
-0.00
13
26
53
357
3.20
4.00
27.5
4.2
—
—
—
0
0
8
11
8.06
3.98
5.8
10.9
—
—
—
0
0
7
8
9.58
3.87
2.9
1.9
—
—
—
0
0
6
5
12.96
3.83
1.3
1.2
—
—
—
0
0
6
5
12.96
3.83
24.2
2.0
—
—
—
0
0
9
16
6.30
3.80
2.3
2.6
13.54
11.29
umol/l
—
9
16
8
12
7.38
3.79
2.5
2.4
0.98
0.99
umol/l
—
8
12
9
17
5.92
3.65
1.2
1.5
—
—
—
0
0
17
65
3.15
3.64
2.6
1.3
—
—
—
0
0
18
72
3.04
3.57
17.5
2.4
—
—
—
0
0
6
6
10.80
3.57
1.0
1.0
—
—
—
0
0
6
6
10.80
3.57
1.0
1.0
—
—
—
0
0
6
6
10.80
3.57
9.0
2.3
3.02
2.28
e9/l
—
6
6
7
10
7.65
3.45
1.0
1.2
—
—
—
0
0
7
10
7.65
3.45
1.0
1.0
—
—
—
0
0
7
10
7.65
3.45
10.1
2.2
70.00
76.40
mg/l
—
7
10
8
14
6.31
3.45
2.1
1.5
—
—
—
0
0
6
7
9.25
3.33
1.5
3.7
—
—
—
0
0
6
7
9.25
3.33
9.8
2.4
43.83
40.86
%
—
6
7
50
346
2.68
3.24
22.5
3.9
9.88
9.06
mm/h
0.26
50
329
11
31
4.03
3.16
3.6
4.1
—
—
—
0
0
13
46
3.26
3.12
2.8
2.5
3.17
2.92
u/l
—
6
21
6
8
8.08
3.12
1.2
1.1
—
—
—
0
0
5
5
10.64
3.02
1.2
1.0
—
—
—
0
0
5
5
10.64
3.02
1.0
1.0
—
—
—
0
0
5
5
10.64
3.02
1.2
1.0
—
—
—
0
0
5
5
10.64
3.02
1.2
1.0
—
—
—
0
0
11
33
3.77
2.97
20.4
25.2
—
—
—
0
0
7
13
5.86
2.95
10.1
2.1
1.67
1.55
mmol/l
—
7
13
6
9
7.18
2.93
26.5
6.3
10.98
8.91
kpa
—
6
9
6
9
7.18
2.93
26.5
6.2
4.73
4.44
kpa
—
6
9
6
9
7.18
2.93
1.7
1.2
—
—
—
0
0
21
103
2.50
2.80
17.1
2.5
0.00
0.00
estimate
-0.00
11
26
5
6
8.86
2.79
1.4
1.3
24.86
19.13
umol/l
—
5
6
11
36
3.44
2.72
20.5
25.1
1.05
0.93
%
0.60
11
36
11
36
3.44
2.72
20.5
25.1
0.79
0.74
%
0.19
11
36
11
36
3.44
2.72
20.5
25.2
95.09
94.29
%
0.12
11
36
8
20
4.39
2.66
1.9
1.5
—
—
—
0
0
11
39
3.16
2.48
20.5
22.7
23.09
23.87
mmol/l
0.59
11
39
9
28
3.54
2.41
6.1
3.0
824.78
1302.57
e6/l
—
9
28
0
59
0.00
2.38
0.0
1.2
—
7.79
—
0
42
0
62
0.00
2.37
0.0
1.2
—
10.56
—
0
50
8
23
3.80
2.35
18.4
3.6
—
—
—
0
0
0
57
0.00
2.18
0.0
1.2
—
0.31
—
0
37
6
15
4.28
2.09
1.3
1.5
—
—
—
0
0
11
45
2.72
2.05
3.2
2.5
5.13
8.68
iu/l
—
6
24
6
16
4.00
1.98
5.8
1.1
—
—
—
0
0
5
11
4.81
1.97
9.2
5.6
—
—
—
0
0
11
47
2.60
1.89
5.7
4.9
—
—
—
0
0
11
47
2.60
1.89
5.5
4.8
—
—
—
0
0
6
19
3.36
1.70
3.0
3.6
—
—
—
0
0
11
50
2.43
1.67
5.7
4.6
2.83
840.39
e6/l
—
6
36
11
50
2.43
1.67
5.7
4.6
1.67
3.97
e6/l
—
6
36
5
15
3.51
1.55
5.0
4.9
28.85
24.25
ug/l
—
5
15
31
223
1.72
1.33
2.4
2.1
—
—
—
0
0
8
35
2.45
1.32
4.5
6.3
3.85
2.49
ug/l
—
8
35
16
95
1.89
1.28
4.0
2.5
111.56
594.41
u/l
1.04
16
95
5
19
2.76
1.24
4.0
1.7
—
—
—
0
0
10
50
2.17
1.24
6.2
4.7
1098.80
370.10
mg/l
—
10
50
6
26
2.43
1.21
2.2
1.2
—
—
—
0
0
7
33
2.25
1.09
5.1
4.2
—
—
—
0
0
68
651
+∞
1.00
126.0
19.4
117.46
125.80
g/l
4.87
68
646
68
651
+∞
1.00
123.1
18.6
290.60
289.86
e9/l
0.02
68
608
68
651
+∞
1.00
132.5
20.5
35.13
37.30
%
3.89
68
642
68
651
+∞
1.00
123.1
18.4
4.20
4.53
e12/l
5.79
68
605
68
651
+∞
1.00
123.1
18.4
28.45
27.90
pg
1.70
68
646
68
652
+∞
1.00
123.1
18.4
7.56
7.74
e9/l
0.18
68
607
68
650
+∞
1.00
123.2
18.4
84.56
82.76
fl
2.33
68
645
0
31
0.00
0.99
0.0
1.6
—
—
—
0
0
6
27
2.34
0.96
5.5
4.7
160.83
52.63
u/ml
—
6
27
10
157
0.57
0.82
1.3
1.2
—
—
—
0
0
6
33
1.90
0.81
4.2
3.1
2045.37
12.11
mg/mmol
—
6
19
38
319
1.43
0.70
3.2
1.8
1.53
1.12
g/l
1.28
30
125
5
27
1.92
0.70
3.6
1.6
—
—
—
0
0
5
33
1.55
0.42
1.2
1.2
—
—
—
0
0
5
34
1.51
0.41
1.2
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
6
41
1.51
0.37
2.8
1.5
—
—
—
0
0
5
38
1.34
0.24
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
12
100
1.24
0.19
1.0
1.0
—
—
—
0
0
18
159
1.18
0.17
4.9
1.8
—
—
—
0
0
40
378
1.14
0.15
3.8
3.1
14.66
14.52
pmol/l
0.09
40
360
5
43
1.18
0.10
1.6
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
6.00
—
0
8
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
138.29
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
0.59
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_HYPOPLASIA_ENAMEL_PRENATAL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_HYPOPLASIA_ENAMEL_PRENATAL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_HYPOPLASIA_ENAMEL_PRENATAL – Hypoplasia of dental enamel, prenatal

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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