≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback

Hypoplasia of dental enamel, prenatal , including avohilmo

Endpoint Browser PheWeb

K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — K00.41
  • Hospital discharge: ICD-10 — K00.41
  • Cause of death: ICD-10 — K00.41

3 out of 7 registries used, show all original rules.

167

4. Check minimum number of events

None

167

5. Include endpoints

None

167

6. Filter based on genotype QC (FinnGen only)

156

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3002 1580 1422
Only index persons 2001 1117 884
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.04
Only index persons 0.04 0.04 0.03
Median age at first event (years)
Whole population - 9.07 7.98
Only index persons 11.19 11.79 10.44

-FinnGen-

Key figures

All Female Male
Number of individuals 156 98 58
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 12.80 16.50 6.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
167
Matched controls
1670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K00.41
ICD-10 Finland
Prenatal enamel hypoplasia
+∞
241.5
167
*
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
18.9
74.6
73
66
127
Kela drug reimbursment
Transplant complication
18.3
39.4
34
23
L04AX01
ATC
azathioprine; systemic
14.4
33.6
33
28
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
13.1
32.4
34
32
H02AB04
ATC
methylprednisolone; systemic
10.3
29.5
37
45
K03.00
ICD-10 Finland
Approximal wear
7.8
24.9
40
65
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
8.8
24.3
34
47
Z94.0
ICD-10 Finland
Kidney transplant status
26.7
21.3
29
13
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
8.0
21.2
32
48
EBA15
NOMESCO Finland
Extraction of multiple teeth
8.0
21.2
32
48
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.5
21.1
30
42
ZX120
NOMESCO Finland
Intravenous
6.1
20.8
43
90
A11CC03
ATC
alfacalcidol; systemic
20.0
20.1
30
18
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.5
20.0
48
115
H02AB09
ATC
hydrocortisone; systemic
6.8
19.6
35
63
L04AD02
ATC
tacrolimus; systemic
18.0
19.3
30
20
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
37.8
18.5
23
7
L04AA06
ATC
mycophenolic acid; systemic
18.4
18.3
28
18
C08CA01
ATC
amlodipine; oral
7.0
18.2
31
53
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
106.5
18.0
19
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.9
17.1
83
336
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
8.3
17.0
24
33
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
31.4
17.0
22
8
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
26.4
17.0
23
10
137
Kela drug reimbursment
Uraemia requiring dialysis
45.0
16.7
20
5
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
19.3
16.7
25
15
SAA03
NOMESCO Finland
Extended examination of mouth
4.6
16.3
131
737
KAC00
NOMESCO Finland
Nephrectomy
37.5
16.1
20
6
TK800
NOMESCO Finland
Hemodialysis
35.4
15.2
19
6
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
62.6
15.1
17
*
ZXD05
NOMESCO Finland
Urgent procedure
3.8
15.0
66
246
ZXE20
NOMESCO Finland
More than three and less than five hours
4.5
14.7
43
119
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
14.6
66
250
TPH07
NOMESCO Finland
Cathetrisation of artery
4.4
14.2
43
122
A12AA04
ATC
calcium carbonate; oral
26.6
14.1
19
8
L04AD01
ATC
ciclosporin; systemic
12.6
14.1
25
23
K00.50
ICD-10 Finland
Dentinal dysplasia
58.5
14.1
16
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.5
13.9
75
316
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
5.5
13.9
30
64
Z99.2
ICD-10 Finland
Dependence on renal dialysis
81.6
13.8
15
*
B03XA01
ATC
erythropoietin; parenteral
28.5
13.7
18
7
Z49.1
ICD-10 Finland
Extracorporeal dialysis
75.8
12.8
14
*
B05DA
ATC
Isotonic solutions
75.8
12.8
14
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
4.4
12.8
37
101
K03.66
ICD-10 Finland
Tooth plaque
3.7
12.7
52
182
Z2221
NOMESCO Finland
Medical doctor
3.3
12.6
70
298
Z2446
NOMESCO Finland
Social worker
3.5
12.5
58
220
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.7
12.4
50
173
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
32.7
11.9
15
5
TK820
NOMESCO Finland
Peritoneal dialysis
32.7
11.9
15
5
TPH04
NOMESCO Finland
Cathetrisation of vein
3.7
11.8
46
155
RD210, ,
NOMESCO Finland
4.8
11.6
29
70
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
3.9
11.6
40
124
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
37.9
11.5
14
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
4.0
11.2
37
111
Z49.2
ICD-10 Finland
Other dialysis
46.7
11.1
13
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.8
11.0
27
64
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
11.7
10.6
19
18
602
Kela drug reimbursment
Children's severe malnutrition
5.0
10.4
24
54
WW500
NOMESCO Finland
Blood transfusion
5.8
10.4
20
38
WX882
NOMESCO Finland
High dependency care
3.4
10.4
46
168
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.6
10.4
21
42
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
9.1
10.2
21
26
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
10.1
70
331
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
21.7
10.0
14
7
4AA09, ,
NOMESCO Finland
28.0
10.0
13
5
1AB02, ,
NOMESCO Finland
14.6
9.9
16
12
V03AE01
ATC
polystyrene sulfonate; oral
58.5
9.8
11
*
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.8
9.7
34
106
R4110
NOMESCO Finland
Physiotherapy
2.9
9.7
70
337
ZXE10
NOMESCO Finland
More than one and less than three hours
2.9
9.6
67
316
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
5.4
9.6
20
41
205
Kela drug reimbursment
Chronic hypertension
8.1
9.6
21
29
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
11.7
9.5
17
16
Z3226
NOMESCO Finland
Physiotherapist
2.8
9.5
67
318
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
8.6
9.5
20
26
SCE00
NOMESCO Finland
Fissure sealant
3.1
9.4
51
209
ZXA00
NOMESCO Finland
Right side
3.7
9.2
33
104
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.1
9.2
47
186
ZXE00
NOMESCO Finland
One hour or less
2.7
9.1
92
521
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.4
9.1
19
39
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.7
9.1
32
100
3A013, ,
NOMESCO Finland
52.8
8.8
10
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.7
8.8
80
429
K06.18
ICD-10 Finland
Another gingival hyperplasia
12.5
8.8
15
13
L04AA01
ATC
[U] ciclosporin
29.2
8.6
11
*
FM2CE, ,
NOMESCO Finland
3.6
8.5
31
99
Z2445
NOMESCO Finland
Psychologist
3.2
8.4
39
145
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.0
8.4
45
182
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
15.5
8.4
13
9
SAA04
NOMESCO Finland
Special examination of mouth
3.5
8.2
31
101
XF400
NOMESCO Finland
ECG with 12 standard connections
2.8
8.2
51
224
I15.8
ICD-10 Finland
Other secondary hypertension
23.4
8.1
11
5
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.5
7.9
30
98
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
47.2
7.8
9
*
783, ,
NOMESCO Finland
47.2
7.8
9
*
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
26.4
7.7
10
*
ZX199
NOMESCO Finland
Other rote
8.3
7.6
16
21
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
2.5
7.6
105
672
XA800
NOMESCO Finland
Neuropsychological investigation
3.3
7.6
32
112
5AB14, ,
NOMESCO Finland
14.2
7.5
12
9
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
83.7
7.5
8
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.1
7.5
22
60
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.8
7.4
24
70
N18.8
ICD-10 Finland
Other chronic renal failure
12.8
7.2
12
10
IEP02
NOMESCO Finland
Child-centred family therapy
3.5
7.1
26
83
WX892
NOMESCO Finland
Monitored bed care
3.4
7.0
27
89
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
11.6
6.9
12
11
SFA10
NOMESCO Finland
One-surface restoration
2.4
6.8
107
710
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
3.8
6.8
22
64
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
17.6
6.8
10
6
R4190
NOMESCO Finland
Nutritional therapy
2.7
6.8
44
196
U14
ICPC
Kidney symptom/complaint
23.6
6.7
9
*
R50.9
ICD-10 Finland
Fever, unspecified
2.5
6.7
58
297
A41.9
ICD-10 Finland
Sepsis, unspecified
6.7
6.7
16
26
K07.24
ICD-10 Finland
Open bite
6.0
6.5
17
31
K02.0
ICD-10 Finland
Caries limited to enamel
2.3
6.5
81
485
TK823
NOMESCO Finland
Peritoneal permeability analysis
72.5
6.5
7
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
6.4
52
258
JAF10
NOMESCO Finland
Repair of umbilical hernia
27.8
6.3
8
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.6
6.3
22
68
K03.64
ICD-10 Finland
Dental calculus supragingival
2.3
6.2
79
474
Z3231
NOMESCO Finland
Registered nurse
2.3
6.2
79
475
RS121, ,
NOMESCO Finland
7.2
6.2
14
21
IEP03
NOMESCO Finland
Focused parental counselling
3.5
6.1
22
69

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
75
6.70
21.65
5.1
2.0
—
—
—
0
0
42
85
6.27
21.03
4.2
2.2
180.54
123.15
u/ml
0.74
24
39
28
19
17.44
17.91
61.6
47.9
6.08
6.75
ug/l
1.02
28
19
29
47
7.26
17.86
2.7
2.3
—
—
—
0
0
32
65
5.85
15.73
2.2
2.0
—
—
—
0
0
60
213
3.84
14.60
46.3
11.0
0.75
0.81
mmol/l
5.63
60
198
24
19
14.54
14.43
3.2
2.4
—
—
—
0
0
47
152
3.91
12.93
4.1
1.8
—
—
—
0
0
43
144
3.67
11.11
6.9
5.2
58.28
63.36
e9/l
0.49
37
92
53
205
3.32
10.93
10.3
7.2
1.52
1.41
%
0.42
53
195
39
129
3.64
10.21
3.4
1.8
—
—
—
0
0
25
60
4.72
10.04
5.4
3.5
—
—
—
0
0
72
350
2.86
9.79
8.8
3.6
—
—
—
0
0
26
66
4.48
9.74
8.3
4.4
0.14
0.81
%
1.46
21
31
16
13
13.46
9.58
3.1
2.5
—
—
—
0
0
54
227
3.04
9.53
9.0
4.6
—
—
—
0
0
20
29
7.68
8.86
5.0
4.5
—
—
—
0
0
33
107
3.60
8.83
2.1
1.5
—
—
—
0
0
45
178
3.09
8.76
24.0
8.1
5.97
5.48
umol/l
0.13
37
142
68
337
2.72
8.72
33.3
11.2
—
—
—
0
0
20
31
7.18
8.49
5.0
4.3
—
—
—
0
0
24
65
4.14
8.24
8.2
5.7
0.06
0.08
%
0.11
18
26
25
70
4.02
8.21
48.0
15.5
118.60
124.79
g/l
0.63
25
70
70
367
2.56
7.86
43.7
10.2
0.85
0.72
mmol/l
0.17
63
273
69
364
2.53
7.60
22.5
8.8
83.67
85.74
%
0.32
69
357
69
369
2.48
7.33
44.8
10.1
5.51
5.68
kpa
1.40
69
358
21
57
4.07
7.17
33.9
17.8
0.65
0.68
%
0.11
21
57
28
95
3.34
6.93
2.4
1.8
—
—
—
0
0
17
29
6.40
6.82
2.9
2.3
—
—
—
0
0
17
29
6.40
6.82
1.4
1.3
—
—
—
0
0
77
449
2.33
6.58
23.9
9.4
29.54
28.80
umol/l
0.04
72
417
56
284
2.46
6.56
19.0
6.2
1.11
1.11
inr
—
10
76
21
61
3.79
6.53
5.1
4.1
162.86
520.00
e6/l
3.44
14
44
16
27
6.43
6.49
1.5
1.2
—
—
—
0
0
65
354
2.37
6.49
40.8
11.0
—
—
—
0
0
86
529
2.29
6.44
24.7
10.6
—
—
—
0
0
17
32
5.79
6.35
3.9
4.4
21.65
27.34
umol/l
0.91
17
32
65
357
2.34
6.34
43.4
10.0
5.44
5.36
kpa
0.16
65
346
75
450
2.21
5.82
16.8
4.2
0.15
0.24
e6/l
0.40
63
343
17
46
4.00
5.81
4.8
5.0
—
—
—
0
0
75
451
2.20
5.78
16.3
4.2
—
—
—
0
0
95
640
2.12
5.34
7.8
3.4
59.97
59.29
ug/l
0.02
90
605
14
27
5.56
5.21
2.6
3.1
29.36
33.70
mmol/l
0.22
14
27
67
402
2.11
5.05
43.9
11.3
4.90
4.95
kpa
0.35
67
389
66
401
2.07
4.76
44.4
11.3
7.38
7.40
ph
—
5
6
15
43
3.73
4.73
3.7
5.2
—
—
—
0
0
29
125
2.60
4.66
34.4
11.9
105.93
105.72
mmol/l
0.12
29
125
15
36
4.47
4.65
14.7
10.2
—
—
—
0
0
118
889
2.12
4.64
34.6
10.8
0.27
0.23
e9/l
0.39
112
748
16
49
3.51
4.60
1.7
1.2
—
—
—
0
0
8
8
10.42
4.57
3.0
1.6
30.00
33.13
pg
—
8
8
10
15
7.01
4.54
1.0
1.8
—
—
—
0
0
10
15
7.01
4.54
23.6
5.3
—
—
—
0
0
45
240
2.20
4.51
11.4
4.7
3.80
2.33
mg/l
0.25
40
172
61
368
2.04
4.43
8.4
3.6
—
—
—
0
0
9
12
7.85
4.41
2.4
2.3
—
—
—
0
0
15
39
4.12
4.32
46.5
19.9
74.35
75.76
%
0.15
15
39
40
207
2.23
4.30
2.5
1.8
1.14
1.30
mmol/l
0.37
40
191
12
25
5.09
4.27
18.5
4.8
—
—
—
0
0
115
872
2.02
4.26
30.1
9.8
0.03
0.04
e9/l
1.56
108
712
49
276
2.10
4.26
2.0
1.8
—
—
—
0
0
53
308
2.06
4.23
13.3
4.0
2.46
1.80
e6/l
0.18
39
193
115
874
2.01
4.20
30.1
9.7
0.59
0.59
e9/l
0.01
108
715
100
725
1.95
4.19
17.5
5.1
167.53
134.60
u/l
1.82
95
682
118
906
2.03
4.18
29.7
9.6
2.49
2.56
e9/l
0.22
113
773
121
939
2.05
4.13
35.4
11.6
3.15
3.56
e9/l
1.59
112
772
55
327
2.02
4.11
5.0
2.6
—
—
—
0
0
37
190
2.22
4.04
4.0
1.7
—
—
—
0
0
74
490
1.92
4.04
18.7
4.3
70.78
28.72
e6/l
0.48
62
378
15
49
3.26
3.91
4.1
2.3
—
—
—
0
0
82
569
1.87
3.82
22.4
5.2
16.26
43.18
e6/l
1.39
63
387
108
818
1.91
3.81
33.8
9.9
—
—
—
0
0
14
39
3.82
3.80
53.2
20.7
—
—
—
0
0
9
16
5.88
3.71
2.4
2.6
0.99
1.01
umol/l
—
9
16
65
422
1.88
3.70
58.5
14.3
24.31
24.44
mmol/l
0.13
65
422
44
251
2.02
3.65
14.6
3.4
7.38
7.40
ph
—
7
35
16
57
3.00
3.64
1.8
1.5
—
—
—
0
0
12
31
4.09
3.57
54.4
24.5
11.37
12.21
%
0.46
12
31
23
102
2.46
3.48
2.3
1.3
—
—
—
0
0
9
18
5.22
3.42
1.1
1.3
—
—
—
0
0
8
14
5.94
3.38
1.0
1.1
—
—
—
0
0
16
60
2.84
3.33
6.4
4.2
41.97
37.50
%
0.54
16
60
27
133
2.23
3.24
2.8
2.7
—
—
—
0
0
6
8
7.72
3.08
8.8
6.6
315.33
242.00
ug/l
—
6
8
7
12
6.03
3.05
24.6
1.8
1.09
1.09
mmol/l
—
7
12
13
46
2.98
2.99
1.2
1.4
—
—
—
0
0
14
52
2.85
2.97
18.2
18.9
—
—
—
0
0
8
17
4.88
2.95
1.0
1.1
—
—
—
0
0
8
18
4.61
2.83
1.4
2.9
—
—
—
0
0
6
10
6.17
2.72
1.3
1.7
23.20
18.12
umol/l
—
6
10
6
10
6.17
2.72
1.3
1.2
—
—
—
0
0
9
24
3.90
2.71
5.4
10.8
—
—
—
0
0
8
19
4.37
2.71
1.0
1.0
—
—
—
0
0
8
19
4.37
2.71
1.0
1.1
—
—
—
0
0
6
11
5.61
2.56
2.5
1.5
2335.33
1301.91
u/ml
—
6
11
8
21
3.95
2.49
24.5
4.1
10.96
9.26
kpa
—
8
21
8
21
3.95
2.49
24.5
4.0
4.75
4.59
kpa
—
8
21
71
522
1.63
2.40
8.4
3.5
6.11
6.13
ph
—
9
79
15
65
2.44
2.39
1.4
1.3
0.22
0.22
g/l
0.01
15
60
5
8
6.40
2.39
1.2
1.4
—
—
—
0
0
5
8
6.40
2.39
1.2
1.4
—
—
—
0
0
5
8
6.40
2.39
1.0
1.7
8.80
8.50
umol/l
—
5
8
9
28
3.34
2.34
1.8
1.8
—
—
—
0
0
15
66
2.40
2.32
1.4
1.2
1.09
1.19
g/l
0.63
15
60
105
854
1.62
2.31
39.1
11.5
0.00
0.00
e9/l
0.50
88
643
5
9
5.69
2.23
1.0
1.0
—
—
—
0
0
5
9
5.69
2.23
29.0
1.9
5.18
5.46
mmol/l
—
5
9
8
24
3.45
2.21
9.1
2.1
1.57
1.80
mmol/l
—
8
24
5
145
0.32
2.14
2.4
1.7
—
—
—
0
0
5
144
0.33
2.14
2.4
1.7
—
—
—
0
0
5
146
0.32
2.14
2.4
1.7
—
—
—
0
0
5
146
0.32
2.14
2.4
1.7
—
—
—
0
0
11
43
2.67
2.12
14.1
3.7
—
—
—
0
0
13
56
2.43
2.10
19.5
18.6
0.97
0.91
%
0.22
13
56
13
56
2.43
2.10
19.5
18.7
95.15
95.08
%
0.01
13
56
13
56
2.43
2.10
19.5
18.6
0.74
0.74
%
0.01
13
56
35
220
1.75
2.10
1.8
1.5
—
—
—
0
0
5
10
5.12
2.08
1.4
1.0
—
—
—
0
0
57
409
1.60
2.08
1.9
2.2
—
—
—
0
0
6
15
4.11
2.06
1.7
1.2
—
—
—
0
0
9
33
2.82
1.96
2.8
1.9
—
—
—
0
0
7
24
3.00
1.74
1.3
1.5
—
—
—
0
0
5
13
3.93
1.72
1.2
1.0
—
—
—
0
0
5
13
3.93
1.72
1.2
1.0
—
—
—
0
0
5
13
3.93
1.72
1.2
1.0
—
—
—
0
0
5
131
0.36
1.71
2.4
1.7
—
—
—
0
0
7
25
2.88
1.67
3.9
5.7
26.73
24.75
ug/l
—
7
25
13
63
2.15
1.64
19.5
16.3
23.08
23.98
mmol/l
0.92
13
63
77
615
1.47
1.64
11.8
3.6
0.00
0.00
estimate
-0.00
17
112
77
616
1.46
1.62
17.8
5.3
0.00
0.00
estimate
-0.00
18
111
20
116
1.82
1.57
2.4
2.5
5.14
5.53
u/l
—
10
68
8
33
2.49
1.56
1.1
1.4
—
—
—
0
0
77
620
1.45
1.55
11.8
3.7
0.00
0.00
estimate
-0.00
18
110
6
21
2.92
1.52
9.0
2.7
3.02
3.01
e9/l
—
6
21
18
103
1.84
1.48
2.6
2.6
15.82
8.83
iu/l
—
10
64
102
872
1.44
1.45
16.3
4.3
—
—
—
0
0
5
16
3.19
1.45
1.0
1.0
—
—
—
0
0
6
22
2.79
1.45
9.8
2.8
43.83
49.50
%
—
6
22
10
46
2.25
1.43
5.7
3.2
846.40
1035.41
e6/l
—
10
46
44
323
1.49
1.40
1.8
1.7
—
—
—
0
0
148
1369
1.71
1.40
43.0
11.3
21.35
22.33
mg/l
0.17
113
997
5
17
3.00
1.37
9.2
7.9
—
—
—
0
0
59
461
1.43
1.37
2.1
1.7
—
—
—
0
0
10
47
2.20
1.36
4.9
6.3
3.18
2.38
ug/l
—
10
47
10
48
2.15
1.30
25.9
3.0
1.25
1.23
mmol/l
—
10
40
25
165
1.61
1.27
2.1
1.5
240.00
756.92
titre
—
5
26
89
756
1.38
1.24
3.4
2.3
5.16
5.31
mmol/l
1.30
83
689
8
39
2.10
1.17
4.8
1.3
—
—
—
0
0
8
40
2.05
1.13
4.5
5.2
121.50
37.35
u/ml
—
8
40
12
66
1.88
1.12
5.2
5.7
—
—
—
0
0
9
47
1.97
1.04
1.8
1.1
—
—
—
0
0
131
1206
1.40
0.99
65.6
14.1
4.07
3.98
mmol/l
1.67
123
1172
73
618
1.32
0.98
2.7
1.7
1.51
1.44
g/l
0.21
50
290
11
62
1.83
0.96
5.7
6.0
—
—
—
0
0
9
155
0.56
0.94
1.1
1.3
2.30
5.73
u/ml
—
9
123
9
155
0.56
0.94
1.1
1.3
0.55
0.94
u/ml
—
9
119
12
72
1.72
0.88
5.3
5.3
1.71
3.35
e6/l
—
7
57
12
72
1.72
0.88
5.3
5.3
134.57
536.16
e6/l
—
7
57
32
243
1.39
0.86
2.1
1.5
91.24
94.55
pmol/l
0.19
14
124
55
457
1.30
0.82
2.1
2.0
—
—
—
0
0
0
24
0.00
0.80
0.0
1.9
—
—
—
0
0
6
34
1.79
0.77
1.7
1.2
—
—
—
0
0
143
1355
1.39
0.73
29.3
8.5
—
—
—
0
0
7
40
1.78
0.72
5.1
5.3
—
—
—
0
0
7
41
1.74
0.71
3.3
1.5
—
—
—
0
0
5
28
1.81
0.66
3.8
1.4
—
—
—
0
0
5
30
1.69
0.62
1.4
1.1
—
—
—
0
0
20
149
1.39
0.61
1.7
2.7
41.83
21.36
ng/l
—
6
55
14
97
1.48
0.61
2.4
1.5
—
—
—
0
0
14
97
1.48
0.61
1.4
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
10
64
1.60
0.60
1.2
1.1
—
—
—
0
0
35
287
1.28
0.58
10.6
3.0
—
—
—
0
0
37
306
1.27
0.57
11.4
3.7
0.00
0.00
estimate
-0.00
16
109
10
65
1.57
0.57
1.2
1.1
—
—
—
0
0
13
93
1.43
0.50
13.5
3.2
—
—
—
0
0
23
283
0.78
0.46
9.0
3.3
1.02
1.02
kg/l
—
5
68
7
50
1.42
0.45
1.0
1.1
—
—
—
0
0
24
293
0.79
0.45
1.3
1.2
—
—
—
0
0
12
87
1.41
0.43
1.5
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
8
60
1.35
0.41
1.1
1.1
—
—
—
0
0
14
106
1.35
0.40
1.0
1.0
—
—
—
0
0
5
35
1.44
0.39
1.4
1.3
—
—
—
0
0
11
80
1.40
0.39
1.1
1.1
—
—
—
0
0
13
98
1.35
0.39
1.2
1.1
—
—
—
0
0
6
47
1.29
0.32
1.5
1.4
—
—
—
0
0
6
47
1.29
0.32
1.5
1.4
—
—
—
0
0
8
67
1.20
0.26
2.8
1.8
—
—
—
0
0
9
77
1.18
0.25
2.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
3.9
—
3.77
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
49
1.23
0.20
1.5
1.5
—
—
—
0
0
7
88
0.79
0.15
2.9
1.7
—
—
—
0
0
12
139
0.85
0.14
1.3
1.2
1.26
6.33
u/ml
—
5
49
5
48
1.04
0.09
2.0
2.9
4.86
0.44
nmol/l
—
5
43
23
215
1.08
0.08
2.2
1.8
—
—
—
0
0
50
488
1.04
0.04
3.2
2.3
—
—
—
0
0
12
129
0.92
0.03
1.2
1.3
15.00
142.52
iu/ml
—
5
37
12
112
1.08
0.03
1.3
1.4
—
—
—
0
0
113
1122
1.02
0.01
5.3
3.7
2.28
2.02
mu/l
1.46
107
1057
101
1003
1.02
0.01
3.7
3.3
14.33
14.45
pmol/l
0.14
91
921
15
146
1.03
0.00
1.3
1.2
10.24
11.27
iu/ml
—
7
36
156
1559
1.01
0.00
68.1
18.0
37.52
38.81
%
3.10
150
1518
27
269
1.00
0.00
1.4
1.9
—
—
—
0
0
63
626
1.01
0.00
1.8
1.8
2.98
4.75
u/ml
—
9
85
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
0.50
—
0
5
0
5
0.00
0.00
0.0
3.0
—
22.80
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
86.32
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
65
0.92
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
-0.00
1.0
1.1
—
—
—
0
0
5
56
0.89
-0.00
1.6
1.7
0.52
3.84
u/ml
—
5
56
8
86
0.93
-0.00
1.4
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO – Hypoplasia of dental enamel, prenatal , including avohilmo

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data