Hypoplasia of dental enamel, prenatal , including avohilmo

K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K00.41
  • Hospital discharge: ICD-10 K00.41
  • Cause of death: ICD-10 K00.41

3 out of 7 registries used, show all original rules.

160

4. Check minimum number of events

None

160

5. Include endpoints

None

160

6. Filter based on genotype QC (FinnGen only)

160

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3002 1580 1422
Only index persons 2001 1117 884
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.04
Only index persons 0.04 0.04 0.03
Median age at first event (years)
Whole population - 9.07 7.98
Only index persons 11.19 11.79 10.44

-FinnGen-

Key figures

All Female Male
Number of individuals 160 98 62
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 11.94 15.35 6.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
128
Matched controls
1278
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K00.41
ICD-10 Finland
Prenatal enamel hypoplasia
+∞
184.8
128
*
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
24.5
37.4
55
38
127
Kela drug reimbursment
Transplant complication
29.6
22.6
30
13
Z94.0
ICD-10 Finland
Kidney transplant status
35.7
20.6
26
9
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
35.7
20.6
26
9
H02AB04
ATC
methylprednisolone; systemic
15.3
18.6
31
26
H02AB09
ATC
hydrocortisone; systemic
12.8
17.2
31
31
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
14.1
16.8
29
26
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
35.4
16.7
21
7
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
29.1
16.7
22
9
L04AX01
ATC
azathioprine; systemic
13.5
16.5
29
27
ZX120
NOMESCO Finland
Intravenous
7.9
16.0
39
67
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
11.0
15.9
31
36
137
Kela drug reimbursment
Uraemia requiring dialysis
44.1
15.9
19
5
A11CC03
ATC
alfacalcidol; systemic
16.9
15.8
25
18
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
27.5
15.7
21
9
L04AA06
ATC
mycophenolic acid; systemic
19.7
15.5
23
14
SAA03
NOMESCO Finland
Extended examination of mouth
5.3
15.1
103
562
L04AD01
ATC
ciclosporin; systemic
18.7
14.6
22
14
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
48.6
14.5
17
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
29.6
13.8
18
7
TK800
NOMESCO Finland
Hemodialysis
29.6
13.8
18
7
EBA15
NOMESCO Finland
Extraction of large number of teeth
9.9
13.7
28
35
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
45.2
13.5
16
*
A12AA04
ATC
calcium carbonate; oral
32.3
13.3
17
6
KAC00
NOMESCO Finland
Nephrectomy
25.8
13.3
18
8
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.7
13.2
42
101
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
11.1
12.7
24
26
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
10.7
12.4
24
27
K03.00
ICD-10 Finland
Approximal wear
12.4
12.3
22
21
Z99.2
ICD-10 Finland
Dependence on renal dialysis
51.9
12.1
14
*
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
6.8
12.1
32
60
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
9.4
12.1
25
32
B03XA01
ATC
erythropoietin; parenteral
25.8
11.9
16
7
C08CA01
ATC
amlodipine; oral
8.9
11.7
25
34
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
38.9
11.5
14
*
TK820
NOMESCO Finland
Peritoneal dialysis
38.9
11.5
14
*
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
7.7
11.4
27
43
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
11.0
55
203
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
12.2
10.7
19
18
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.6
10.6
65
284
B05DA
ATC
Isotonic solutions
35.8
10.5
13
*
1AB02
NOMESCO Finland
NA
21.0
10.5
15
8
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
5.1
10.4
35
88
TPH07
NOMESCO Finland
Cathetrisation of artery
4.8
10.2
37
100
Z49.1
ICD-10 Finland
Extracorporeal dialysis
43.8
10.2
12
*
Z49.2
ICD-10 Finland
Other dialysis
43.8
10.2
12
*
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
43.8
10.2
12
*
R4110
NOMESCO Finland
Physiotherapy
3.6
10.0
60
254
4AA09
NOMESCO Finland
NA
32.8
9.6
12
*
I15.8
ICD-10 Finland
Other secondary hypertension
107.7
9.5
10
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
9.5
70
340
V03AE01
ATC
polystyrene sulfonate; oral
+∞
9.5
9
*
WX110
NOMESCO Finland
Local anesthesy
3.7
9.2
103
678
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
26.2
9.1
12
5
ZX199
NOMESCO Finland
Other rote
12.0
9.1
16
15
205
Kela drug reimbursment
Chronic hypertension
8.7
9.0
19
25
K06.18
ICD-10 Finland
Another gingival hyperplasia
15.5
8.9
14
10
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
4.7
8.7
31
82
5AB14
NOMESCO Finland
NA
21.9
8.6
12
6
L04AA01
ATC
[U] ciclosporin; systemic
29.8
8.6
11
*
RD210
NOMESCO Finland
NA
5.1
8.6
28
67
3A013
NOMESCO Finland
NA
96.1
8.5
9
*
783
NOMESCO Finland
NA
+∞
8.4
8
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
15.9
8.4
13
9
602
Kela drug reimbursment
Children's severe malnutrition
6.3
8.3
22
41
K03.66
ICD-10 Finland
Tooth plaque
3.7
8.3
41
146
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.7
8.3
40
140
SFA10
NOMESCO Finland
Fillning on one surface of tooth
3.0
8.2
81
464
IGY02
NOMESCO Finland
Psychiatric monitoring contact
5.3
8.1
25
56
SFA40
NOMESCO Finland
Replacement of krone of tooth
6.8
8.1
20
34
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
8.3
8.0
17
23
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
7.9
41
150
K00.50
ICD-10 Finland
Dentinal dysplasia
16.4
7.9
12
8
TPH04
NOMESCO Finland
Cathetrisation of vein
3.6
7.8
39
139
SAA04
NOMESCO Finland
Special inverstigation of mouth
4.3
7.8
30
85
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
19.9
7.7
11
6
WW500
NOMESCO Finland
Blood transfusion
7.3
7.7
18
28
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
4.2
7.6
30
87
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.0
7.5
24
56
SCE00
NOMESCO Finland
Fissure closure of tooth
3.4
7.4
42
162
K02.0
ICD-10 Finland
Caries limited to enamel
2.9
7.1
54
258
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.6
7.0
20
41
RS121
NOMESCO Finland
NA
9.1
7.0
14
17
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
2.7
7.0
77
456
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
11.9
7.0
12
11
IEP02
NOMESCO Finland
Child-centred family therapy
5.4
6.9
20
42
A41.9
ICD-10 Finland
Sepsis, unspecified
8.6
6.8
14
18
K02.1
ICD-10 Finland
Caries of dentine
2.7
6.7
84
532
WX882
NOMESCO Finland
High dependency care
3.2
6.6
39
155
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
6.2
6.6
17
31
Z01.2
ICD-10 Finland
Dental examination
2.7
6.4
89
588
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
6.4
52
253
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
28.2
6.3
8
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
27
18
17.84
31.26
60.8
46.6
6.1
6.8
ug/l
0.92
27
18
24
18
15.51
25.96
3.2
2.4
—
—
—
0
0
39
72
6.84
21.48
4.9
2.0
—
—
—
0
0
40
84
6.02
19.23
4.2
2.2
187.3
122.6
u/ml
0.85
23
38
29
44
7.83
19.01
2.7
2.3
—
—
—
0
0
59
197
4.16
15.93
44.9
11.4
0.8
0.8
mmol/l
4.63
59
182
31
61
6.06
15.79
2.2
2.0
—
—
—
0
0
15
12
13.69
15.35
3.1
2.6
—
—
—
0
0
20
29
7.74
13.47
5.0
4.5
—
—
—
0
0
20
31
7.23
12.69
5.0
4.5
—
—
—
0
0
42
132
3.96
12.01
6.5
5.6
58.2
63.2
e9/l
0.45
36
88
52
191
3.55
11.81
10.1
7.5
1.5
1.4
%
0.41
52
181
45
151
3.75
11.69
4.1
1.8
—
—
—
0
0
70
329
3.00
10.33
8.3
3.6
—
—
—
0
0
25
59
4.84
10.27
5.5
3.7
—
—
—
0
0
37
119
3.74
10.13
2.8
1.8
—
—
—
0
0
25
62
4.59
9.66
8.3
4.5
0.0
0.7
%
1.35
15
14
66
314
2.88
9.35
31.4
11.3
—
—
—
0
0
16
27
6.47
9.32
2.8
2.4
—
—
—
0
0
51
212
3.06
9.21
8.9
4.5
—
—
—
0
0
16
28
6.24
8.99
1.4
1.4
—
—
—
0
0
16
29
6.02
8.69
3.6
4.3
22.0
27.7
umol/l
0.81
16
29
25
68
4.17
8.56
9.0
5.7
0.2
0.6
%
0.81
18
23
15
26
6.26
8.50
1.5
1.2
—
—
—
0
0
43
169
3.11
8.48
19.2
8.2
5.0
5.4
umol/l
0.14
35
136
31
100
3.60
8.37
2.0
1.4
—
—
—
0
0
23
61
4.24
8.13
9.3
6.0
0.0
0.0
%
0.00
18
20
23
61
4.24
8.13
8.5
6.0
0.0
0.0
%
0.00
15
17
24
66
4.10
8.09
41.1
15.0
119.7
125.5
g/l
0.56
24
66
67
342
2.65
8.06
41.9
10.3
1.0
0.8
mmol/l
0.35
60
254
66
344
2.56
7.51
43.0
10.2
5.5
5.7
kpa
1.05
66
333
66
344
2.56
7.51
20.8
8.8
84.3
85.9
%
0.22
66
339
20
51
4.34
7.41
3.4
2.4
—
—
—
0
0
20
51
4.34
7.41
3.4
2.4
—
—
—
0
0
20
51
4.34
7.41
3.4
2.4
—
—
—
0
0
20
51
4.34
7.41
3.4
2.4
—
—
—
0
0
27
88
3.49
7.14
2.5
1.8
—
—
—
0
0
52
249
2.61
6.97
13.8
4.6
1.1
1.1
inr
—
8
65
13
25
5.57
6.61
2.8
2.8
30.3
32.0
mmol/l
0.07
13
25
62
332
2.42
6.49
41.0
10.1
—
—
—
0
0
62
333
2.41
6.44
41.7
10.1
5.4
5.3
kpa
0.28
62
322
73
422
2.34
6.40
18.8
9.5
25.3
28.6
umol/l
0.20
68
391
10
15
7.04
6.39
1.0
1.8
—
—
—
0
0
10
15
7.04
6.39
23.6
5.4
—
—
—
0
0
15
34
4.76
6.38
14.7
10.4
—
—
—
0
0
17
43
4.30
6.35
4.8
3.7
—
—
—
0
0
82
510
2.25
5.93
25.7
10.8
—
—
—
0
0
12
24
5.32
5.84
18.5
4.8
—
—
—
0
0
92
613
2.18
5.45
7.9
3.3
60.0
59.6
ug/l
0.01
87
578
19
59
3.52
5.37
5.6
4.2
162.9
516.0
e6/l
3.31
14
43
71
431
2.16
5.30
17.6
4.2
0.1
0.2
e6/l
0.41
61
324
16
45
3.84
5.19
1.7
1.2
—
—
—
0
0
71
434
2.14
5.18
17.0
4.2
—
—
—
0
0
14
36
4.17
5.10
39.5
21.1
75.1
75.9
%
0.08
14
36
95
654
2.11
5.02
29.0
10.3
—
—
—
0
0
8
7
11.94
4.84
3.0
1.7
30.0
34.0
pg
—
8
7
63
376
2.11
4.82
44.4
10.4
7.4
7.4
ph
—
5
6
59
344
2.13
4.80
8.5
3.3
—
—
—
0
0
97
687
2.05
4.59
16.7
5.0
161.2
132.7
u/l
1.66
92
647
113
851
2.12
4.46
34.1
11.0
0.3
0.2
e9/l
0.37
107
717
47
259
2.15
4.36
2.0
1.7
—
—
—
0
0
8
9
9.28
4.33
2.0
2.3
—
—
—
0
0
13
36
3.84
4.30
41.9
22.0
—
—
—
0
0
14
42
3.56
4.15
3.9
5.2
—
—
—
0
0
44
241
2.14
4.12
14.6
3.5
7.4
7.4
ph
—
7
34
113
865
2.04
4.08
29.2
9.7
2.5
2.6
e9/l
0.29
108
737
110
835
2.02
4.06
29.7
9.8
0.0
0.0
e9/l
1.37
103
682
110
835
2.02
4.06
29.6
9.8
0.6
0.6
e9/l
0.01
103
683
116
900
2.05
3.99
34.9
11.7
3.2
3.6
e9/l
1.57
107
740
11
29
4.00
3.87
46.3
25.7
11.6
12.2
%
0.26
11
29
9
15
6.29
3.87
2.4
2.6
1.0
1.0
umol/l
—
9
15
35
180
2.21
3.82
3.7
1.7
—
—
—
0
0
62
395
1.93
3.79
55.6
13.6
24.2
24.5
mmol/l
0.26
62
395
14
45
3.31
3.75
3.7
2.3
—
—
—
0
0
70
471
1.86
3.58
19.6
4.2
72.6
29.5
e6/l
0.48
60
362
49
293
1.97
3.58
14.1
4.0
2.5
1.8
e6/l
0.19
38
183
15
52
3.08
3.57
1.8
1.5
—
—
—
0
0
37
200
2.11
3.55
2.1
1.9
1.1
1.3
mmol/l
0.37
37
184
51
310
1.95
3.55
5.3
2.5
—
—
—
0
0
78
545
1.84
3.53
23.2
5.1
16.6
44.5
e6/l
1.38
61
371
22
97
2.47
3.38
2.3
1.3
—
—
—
0
0
26
126
2.27
3.25
2.8
2.7
—
—
—
0
0
7
12
6.04
3.05
24.6
1.8
1.1
1.1
mmol/l
—
7
12
13
46
2.99
3.00
11.1
20.7
—
—
—
0
0
8
17
4.89
2.96
1.0
1.2
—
—
—
0
0
9
22
4.27
2.93
5.4
9.4
—
—
—
0
0
6
9
6.87
2.89
1.3
1.7
23.2
18.9
umol/l
—
6
9
8
18
4.62
2.83
1.1
1.3
—
—
—
0
0
5
6
8.55
2.77
1.4
1.3
—
—
—
0
0
7
14
5.17
2.76
1.0
1.1
—
—
—
0
0
8
20
4.15
2.60
24.5
4.0
11.0
9.2
kpa
—
8
20
8
20
4.15
2.60
24.5
4.0
4.8
4.6
kpa
—
8
20
40
247
1.83
2.58
14.9
4.2
—
—
—
0
0
6
11
5.62
2.56
2.5
1.5
2335.3
1301.9
u/ml
—
6
11
5
8
6.41
2.39
1.2
1.4
—
—
—
0
0
5
8
6.41
2.39
1.2
1.4
—
—
—
0
0
5
8
6.41
2.39
1.0
1.8
8.8
8.5
umol/l
—
5
8
7
17
4.25
2.39
1.0
1.1
—
—
—
0
0
11
41
2.81
2.33
14.1
3.8
—
—
—
0
0
12
47
2.68
2.33
1.2
1.4
—
—
—
0
0
8
23
3.60
2.30
9.1
2.1
1.6
1.8
mmol/l
—
8
23
7
18
4.02
2.28
1.0
1.1
—
—
—
0
0
7
18
4.02
2.28
1.0
1.0
—
—
—
0
0
62
448
1.63
2.25
9.2
3.4
—
—
—
0
0
5
9
5.69
2.23
1.0
1.0
—
—
—
0
0
5
9
5.69
2.23
29.0
1.9
5.2
5.5
mmol/l
—
5
9
7
19
3.80
2.17
1.4
2.8
—
—
—
0
0
56
398
1.63
2.15
1.9
2.2
—
—
—
0
0
5
145
0.32
2.15
2.4
1.7
—
—
—
0
0
5
144
0.33
2.15
2.4
1.7
—
—
—
0
0
5
144
0.33
2.15
2.4
1.7
—
—
—
0
0
14
62
2.38
2.14
1.4
1.3
0.2
0.2
g/l
0.05
14
57
5
10
5.12
2.08
1.2
1.2
—
—
—
0
0
14
63
2.34
2.07
1.4
1.3
1.1
1.2
g/l
0.62
14
57
6
15
4.11
2.06
1.7
1.2
—
—
—
0
0
34
214
1.75
2.04
1.8
1.5
—
—
—
0
0
12
51
2.46
2.00
11.8
19.8
95.0
94.9
%
0.02
12
51
12
51
2.46
2.00
11.8
19.7
1.0
0.9
%
0.17
12
51
12
51
2.46
2.00
11.8
19.7
0.7
0.7
%
0.03
12
51
5
142
0.33
2.00
2.4
1.7
—
—
—
0
0
8
28
2.95
1.89
1.9
1.7
—
—
—
0
0
99
821
1.54
1.87
39.5
11.7
0.0
0.0
e9/l
0.50
83
618
5
12
4.26
1.83
1.2
1.0
—
—
—
0
0
5
12
4.26
1.83
1.2
1.0
—
—
—
0
0
5
12
4.26
1.83
1.2
1.0
—
—
—
0
0
74
581
1.51
1.78
12.1
3.4
0.0
0.0
estimate
0.00
15
100
74
582
1.51
1.76
18.2
5.1
0.0
0.0
estimate
0.00
17
104
7
24
3.00
1.74
1.3
1.5
—
—
—
0
0
7
24
3.00
1.74
3.9
5.9
26.7
24.8
ug/l
—
7
24
5
13
3.93
1.73
2.2
2.2
—
—
—
0
0
5
130
0.36
1.72
2.4
1.7
—
—
—
0
0
74
586
1.49
1.68
12.1
3.5
0.0
0.0
estimate
0.00
17
103
99
832
1.50
1.67
16.7
4.2
—
—
—
0
0
8
32
2.58
1.62
2.8
1.9
—
—
—
0
0
20
116
1.83
1.57
2.5
2.5
5.1
5.5
u/l
—
10
68
12
58
2.16
1.53
11.8
17.1
23.2
24.2
mmol/l
1.01
12
58
18
102
1.86
1.52
2.6
2.6
15.8
8.9
iu/l
—
10
63
6
21
2.93
1.52
9.0
2.7
3.0
3.0
e9/l
—
6
21
6
22
2.79
1.45
9.8
2.8
43.8
49.5
%
—
6
22
10
46
2.25
1.43
4.9
6.3
3.2
2.4
ug/l
—
10
46
43
316
1.49
1.37
1.8
1.7
—
—
—
0
0
10
47
2.20
1.37
25.9
3.0
1.2
1.2
mmol/l
—
10
39
24
156
1.63
1.29
2.0
1.5
240.0
761.6
titre
—
5
25
9
44
2.11
1.29
1.8
1.1
—
—
—
0
0
8
35
2.35
1.29
4.8
1.3
—
—
—
0
0
56
439
1.42
1.28
2.1
1.7
—
—
—
0
0
141
1308
1.66
1.25
41.6
11.0
21.1
22.6
mg/l
0.29
107
951
32
226
1.52
1.23
2.1
1.5
91.2
93.5
pmol/l
0.13
14
115
85
727
1.36
1.12
3.4
2.3
5.2
5.3
mmol/l
1.13
79
661
8
41
2.00
1.10
1.0
1.0
173.1
162.7
g/l
—
8
41
71
592
1.36
1.10
2.7
1.7
1.5
1.4
g/l
0.35
48
276
5
21
2.42
1.10
3.8
1.3
—
—
—
0
0
7
32
2.24
1.09
1.1
1.4
—
—
—
0
0
125
1145
1.42
1.03
63.9
13.8
4.1
4.0
mmol/l
1.71
117
1110
7
37
1.93
0.95
3.3
1.5
—
—
—
0
0
9
154
0.56
0.94
1.1
1.3
0.6
0.9
u/ml
—
9
118
9
154
0.56
0.94
1.1
1.3
2.3
5.8
u/ml
—
9
122
53
434
1.33
0.90
1.9
2.1
—
—
—
0
0
11
65
1.74
0.84
5.5
5.8
—
—
—
0
0
0
24
0.00
0.80
0.0
1.9
—
—
—
0
0
144
1371
1.50
0.78
56.4
16.0
36.7
38.5
%
3.49
129
1253
14
92
1.57
0.75
2.4
1.5
—
—
—
0
0
10
60
1.71
0.74
6.2
6.1
—
—
—
0
0
10
60
1.71
0.74
1.2
1.2
—
—
—
0
0
10
61
1.68
0.70
1.2
1.1
—
—
—
0
0
137
1301
1.37
0.67
28.9
8.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.8
—
—
—
0
0
12
81
1.52
0.59
1.5
1.4
—
—
—
0
0
35
290
1.26
0.54
12.0
3.4
0.0
0.0
estimate
0.00
15
103
6
40
1.52
0.52
5.8
5.3
—
—
—
0
0
11
76
1.48
0.49
1.1
1.1
—
—
—
0
0
33
276
1.25
0.47
11.2
3.0
—
—
—
0
0
7
48
1.48
0.47
1.0
1.1
—
—
—
0
0
23
283
0.78
0.46
1.3
1.2
—
—
—
0
0
18
139
1.33
0.46
1.8
2.6
41.8
20.8
ng/l
—
6
51
5
33
1.53
0.41
1.8
1.2
—
—
—
0
0
8
59
1.37
0.41
1.1
1.1
—
—
—
0
0
5
35
1.44
0.39
1.4
1.3
—
—
—
0
0
12
89
1.38
0.39
1.0
1.0
20.1
19.4
mmol/l
0.36
12
89
12
89
1.38
0.39
14.6
3.1
—
—
—
0
0
12
90
1.36
0.37
1.0
1.0
—
—
—
0
0
6
46
1.32
0.33
1.5
1.4
—
—
—
0
0
6
46
1.32
0.33
1.5
1.4
—
—
—
0
0
12
92
1.33
0.33
1.5
1.1
—
—
—
0
0
8
62
1.31
0.28
2.8
1.8
—
—
—
0
0
12
95
1.28
0.27
1.2
1.1
—
—
—
0
0
9
75
1.21
0.25
2.0
1.6
—
—
—
0
0
5
40
1.26
0.22
1.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
48
1.26
0.20
1.5
1.5
—
—
—
0
0
7
86
0.81
0.15
1.4
1.2
—
—
—
0
0
7
85
0.82
0.15
2.9
1.7
—
—
—
0
0
5
45
1.11
0.10
2.0
3.0
4.9
0.4
nmol/l
—
5
40
62
599
1.06
0.09
1.8
1.8
3.0
5.0
u/ml
—
9
80
12
130
0.92
0.05
1.2
1.2
1.3
6.8
u/ml
—
5
45
97
957
1.03
0.04
3.7
3.4
14.2
14.5
pmol/l
0.52
87
878
12
111
1.09
0.04
1.3
1.4
—
—
—
0
0
47
461
1.03
0.02
3.3
2.2
—
—
—
0
0
108
1071
1.03
0.02
5.5
3.7
2.3
2.0
mu/l
1.55
102
1009
27
263
1.03
0.01
1.4
1.9
—
—
—
0
0
21
204
1.03
0.00
2.1
1.8
—
—
—
0
0
14
137
1.02
0.00
1.4
1.2
10.4
11.4
iu/ml
—
6
34
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
0.5
—
0
5
0
5
0.00
0.00
0.0
3.0
—
22.8
—
0
5
6
64
0.94
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
62
0.97
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
86.3
—
0
5

Mortality – FinRegistry

Association

Association between endpoint K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_HYPOPLASIA_ENAMEL_PRENATAL_INCLAVO – Hypoplasia of dental enamel, prenatal , including avohilmo

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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