neurotic excoriation: a condition in which patients produce skin lesions through repetitive, compulsive excoriation of their skin.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
186 |
4. Check minimum number of eventsNone |
186 |
5. Include endpointsNone |
186 |
6. Filter based on genotype QC (FinnGen only) |
186 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L98
- Name in latin
- Dermatitis artificialis
Similar endpoints
↥List of similar endpoints to
Factitial dermatitis
based on the number of shared cases.
Similar with more cases:
- Other disorders of skin and subcutaneous tissue, not elsewhere classified
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1738 | 1165 | 556 |
| Only index persons | 1405 | 982 | 423 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.02 |
| Only index persons | 0.03 | 0.04 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 54.96 | 55.45 | 53.93 |
| Only index persons | 53.35 | 54.22 | 51.35 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 186 | 130 | 56 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.02 |
| Median age at first event (years) | 48.33 | 47.13 | 51.11 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 172
- Matched controls
- 1718
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L98.1
ICD-10 Finland
Factitial dermatitis
+∞
172.1
135
*
E0000UV
ATC
NA
6.0
26.4
118
459
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
8.1
24.9
63
115
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
263.7
23.2
23
*
D07AC01
ATC
betamethasone; topical
5.3
23.0
102
373
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.9
21.4
72
188
69840
ICD-8 Finland
Pruritus and related conditions, Dermatitis factitia (artifacta)
+∞
21.3
20
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
9.8
21.2
45
60
D07AD01
ATC
clobetasol; topical
6.3
20.0
60
134
L28.1
ICD-10 Finland
Prurigo nodularis
112.5
19.0
20
*
D07AC13
ATC
mometasone; topical
4.7
18.9
86
304
6984A
ICD-9 Finland
Pruritus and related conditions, Dermatitis factitia [artifacta][LICHENIFICATIO ET DERMATITIS ARTEFACTA]
+∞
18.0
17
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
7.0
17.8
47
87
L29.9
ICD-10 Finland
Pruritus, unspecified
23.9
16.5
23
11
D09AB01
ATC
zinc bandage without supplements; topical
21.9
16.1
23
12
E000001
ATC
NA
4.6
15.8
64
195
D07AB02
ATC
hydrocortisone butyrate; topical
4.0
15.3
82
320
D07BA04
ATC
hydrocortisone and antiseptics; topical
6.0
14.9
44
93
J01FF01
ATC
clindamycin; systemic
4.1
14.8
73
262
S97
ICPC
Chronic ulcer skin
12.0
14.3
26
25
F32.9
ICD-10 Finland
Depressive episode, unspecified
5.3
14.3
47
113
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
6.5
13.7
37
69
D07CC01
ATC
betamethasone and antibiotics; topical
5.2
13.4
45
110
D07BC01
ATC
betamethasone and antiseptics; topical
5.7
13.4
41
90
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
5.3
13.0
42
98
A46
ICD-10 Finland
Erysipelas
5.1
12.7
43
106
D07AA02
ATC
hydrocortisone; topical
4.6
12.5
47
129
N06AX16
ATC
venlafaxine; oral
4.6
12.3
47
131
R06AE07
ATC
cetirizine; oral
3.2
12.1
102
538
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
32.6
11.9
15
5
C03CA01
ATC
furosemide; systemic
3.3
11.1
69
288
N05AH04
ATC
quetiapine; oral
3.9
10.8
50
165
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
64.1
10.8
12
*
J01CF05
ATC
flucloxacillin; systemic
15.6
10.7
17
12
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
5.8
10.7
31
63
N05CF01
ATC
zopiclone; oral
3.2
10.7
73
322
TQW80
NOMESCO Finland
Local dermatologic skincare
12.4
9.8
17
15
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
7.7
9.7
22
32
A10AE04
ATC
insulin glargine; parenteral
5.1
9.7
31
71
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
13.4
9.6
16
13
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
+∞
9.5
9
*
D07AB08
ATC
desonide; topical
4.7
9.4
33
83
A06AD11
ATC
lactulose; oral
3.7
9.4
45
151
N05BA04
ATC
oxazepam; oral
3.0
9.3
65
287
N03AX12
ATC
gabapentin; oral
3.9
9.1
39
119
E000002
ATC
NA
4.1
9.1
37
108
N05AA02
ATC
levomepromazine; systemic
7.7
8.8
20
29
J01DB01
ATC
cefalexin; oral
3.6
8.8
151
1145
N03AX16
ATC
pregabalin; oral
3.1
8.7
57
240
103
Kela drug reimbursment
Diabetes, insulin-treated
2.9
8.7
62
276
N06AX21
ATC
duloxetine; oral
4.3
8.7
33
90
R60.0
ICD-10 Finland
Localized oedema
4.4
8.7
32
85
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.9
8.6
21
34
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
6.9
8.6
21
34
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
29.2
8.6
11
*
J01AA07
ATC
tetracycline; systemic
3.5
8.5
42
144
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.9
8.5
28
66
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
94.5
8.5
9
*
SPAT1240
SPAT
Therapeutic discussion
3.9
8.3
35
105
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
5.2
8.2
25
54
N05BB01
ATC
hydroxyzine; systemic
4.9
8.1
26
60
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
7.6
8.0
18
26
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
7.0
8.0
19
30
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.9
7.9
55
237
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
5.7
7.9
22
43
SPAT1301
SPAT
No procedures
2.6
7.7
73
381
L30.3
ICD-10 Finland
Infective dermatitis
7.4
7.5
17
25
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
3.7
7.5
33
103
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
7.4
64
314
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
10.0
7.4
14
15
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
10.0
7.4
14
15
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
5.5
7.4
21
42
M79.6
ICD-10 Finland
Pain in limb
2.5
7.4
76
410
L89
ICD-10 Finland
Decubitus ulcer and pressure area
+∞
7.3
7
*
SPAT1262
SPAT
Handing over of treatment supplies
3.2
7.3
43
164
J01MA02
ATC
ciprofloxacin; systemic
2.5
7.3
77
423
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
31.5
7.2
9
*
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
21.1
7.2
10
5
H02AB06
ATC
prednisolone; systemic
2.4
7.2
91
545
A10AE05
ATC
insulin detemir; parenteral
6.0
7.2
19
35
SPAT1254
SPAT
Administration of medicine
3.3
7.1
38
137
N02AX02
ATC
tramadol; systemic, rectal
2.4
7.0
80
453
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
8.9
7.0
14
17
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.0
6.8
27
77
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
6.7
40
154
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
12.9
6.7
11
9
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
4.0
6.7
26
73
SPAT1260
SPAT
Consultation of another employee
3.0
6.7
43
174
Z00.8
ICD-10 Finland
Other general examinations
4.6
6.6
22
53
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.9
6.5
26
75
H3603, E103
ICD-10 Finland
NA
15.1
6.5
10
7
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
72.4
6.5
7
*
L28.2
ICD-10 Finland
Other prurigo
72.4
6.5
7
*
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
72.4
6.5
7
*
A10AA01
ATC
NA
8.7
6.5
13
16
N05AX08
ATC
risperidone; systemic
4.0
6.4
25
70
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
6.4
42
173
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
7.5
6.4
14
20
L28.0
ICD-10 Finland
Lichen simplex chronicus
18.9
6.3
9
5
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
18.9
6.3
9
5
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
4.1
6.3
24
66
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
6.0
6.2
16
29
S10
ICPC
Boil/carbuncle
6.0
6.2
16
29
A10AA02
ATC
NA
6.5
6.2
15
25
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
10.6
6.1
11
11
N06AX11
ATC
mirtazapine; oral
2.4
6.1
64
343
ZXA00
NOMESCO Finland
Right side
2.5
6.1
57
289
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
3.2
6.1
31
109
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
74
342
2.93
11.03
2.7
2.1
3.7
2.9
mg/l
0.56
67
291
107
616
2.74
10.27
8.6
3.6
34.4
35.8
g/l
1.46
99
577
88
479
2.59
9.19
4.3
2.8
56.8
29.2
u/l
0.48
81
457
48
211
2.72
7.52
3.6
2.0
12.5
13.6
umol/l
0.39
43
188
49
220
2.67
7.35
2.8
1.7
—
—
—
0
0
39
159
2.84
7.01
15.5
19.1
1.0
1.4
inr
—
10
23
56
274
2.49
7.01
1.8
1.7
1405.2
1088.4
nmol/l
1.08
45
203
43
187
2.69
6.83
3.9
2.0
2.4
2.4
g/l
0.08
37
171
55
275
2.42
6.52
2.0
1.8
517.8
473.2
pmol/l
0.47
47
230
31
116
3.01
6.48
6.5
3.2
2.2
2.2
mmol/l
0.03
25
82
101
662
2.15
6.13
4.2
2.6
108.0
91.9
ug/l
0.42
91
603
72
419
2.17
5.88
2.7
1.9
183.6
192.6
u/l
0.05
66
397
35
151
2.62
5.60
2.3
1.6
—
—
—
0
0
76
459
2.11
5.59
4.5
2.4
42.9
58.5
u/l
4.77
69
425
38
174
2.49
5.37
3.9
2.1
19.5
22.1
%
0.57
26
147
103
716
1.98
4.97
12.1
5.8
1.2
1.2
mmol/l
1.75
86
601
34
154
2.48
4.90
2.2
1.7
—
—
—
0
0
97
667
1.95
4.77
9.5
5.1
1.2
1.2
mmol/l
1.36
88
596
25
100
2.73
4.61
2.0
1.3
—
—
—
0
0
35
168
2.33
4.44
2.9
2.6
6.3
7.7
umol/l
0.24
29
145
49
272
2.09
4.36
4.5
3.0
247.9
157.9
ng/l
0.15
32
197
59
351
2.00
4.34
1.5
1.2
0.9
1.2
u/ml
0.20
18
98
20
73
2.95
4.34
4.7
3.5
2.0
1.4
mmol/l
0.26
15
52
42
224
2.13
4.13
3.3
3.0
0.8
0.8
mmol/l
0.12
37
213
22
88
2.70
4.05
2.7
3.2
4.4
4.6
pmol/l
0.22
17
77
76
505
1.85
3.96
3.4
3.0
—
—
—
0
0
106
784
1.82
3.87
7.5
5.6
9.8
10.3
umol/l
0.27
100
743
76
509
1.83
3.84
3.6
2.9
2.3
2.4
mmol/l
0.84
58
444
140
1133
1.95
3.79
5.7
4.0
15.8
11.8
mm/h
2.13
129
1045
28
133
2.30
3.62
4.0
3.3
—
—
—
0
0
142
1163
1.93
3.60
5.5
3.8
14.5
14.7
pmol/l
0.36
128
1055
89
642
1.74
3.39
2.8
2.2
74.5
76.9
nmol/l
0.36
83
568
33
174
2.09
3.31
1.8
1.6
1.5
1.4
%
0.23
23
151
113
876
1.74
3.29
14.2
8.7
4.4
4.1
e9/l
0.56
104
768
9
20
4.67
3.15
1.3
1.6
—
—
—
0
0
62
411
1.76
3.13
3.0
2.9
0.2
0.4
e6/l
1.48
45
308
30
156
2.10
3.12
8.7
5.5
2.1
1.0
mmol/l
0.66
23
121
63
420
1.76
3.12
3.2
2.7
3145.9
1191.1
ng/l
0.43
54
352
82
590
1.70
3.08
2.1
1.9
92.9
96.7
pmol/l
0.36
46
298
9
21
4.45
3.03
1.4
1.4
—
—
—
0
0
16
64
2.64
2.96
7.8
2.3
25.2
24.2
mmol/l
0.80
16
64
50
316
1.80
2.95
1.8
1.7
0.8
1.1
mg/l
0.93
33
252
22
103
2.29
2.94
17.0
5.7
13.9
8.2
mmol/l
1.74
22
95
6
9
6.84
2.89
3.5
3.4
162.0
107.0
nmol/l
—
6
9
56
369
1.74
2.86
2.9
2.5
11405.8
8047.1
umol/l
0.11
46
308
170
1528
2.31
2.71
31.7
14.0
4.0
4.0
mmol/l
0.58
164
1479
11
39
2.93
2.52
3.4
4.1
1.9
1.4
mg/l
0.89
11
34
14
58
2.53
2.43
2.5
1.8
—
—
—
0
0
11
40
2.86
2.42
1.1
1.0
—
0.9
—
0
7
138
1178
1.66
2.38
11.5
6.7
89.0
78.1
u/l
1.71
131
1094
59
413
1.63
2.35
2.2
1.6
1.6
1.4
mmol/l
0.43
47
360
90
697
1.56
2.34
6.4
3.7
—
—
—
0
0
52
356
1.64
2.26
2.8
2.1
—
—
—
0
0
42
272
1.70
2.24
2.8
2.6
2.4
2.4
mmol/l
0.08
34
238
5
9
5.67
2.22
8.8
7.7
0.5
0.6
mmol/l
—
5
9
74
555
1.55
2.18
4.4
3.5
77.3
41.8
ng/l
0.56
46
370
158
1410
1.80
2.18
6.9
4.6
1.9
1.9
mu/l
0.26
146
1283
9
30
3.10
2.18
1.3
1.7
—
—
—
0
0
167
1519
1.97
2.12
30.0
12.3
24.3
22.2
mg/l
0.40
145
1185
9
31
3.00
2.10
2.4
1.5
—
—
—
0
0
5
12
4.25
1.83
1.0
1.2
—
—
—
0
0
5
12
4.25
1.83
1.8
1.3
—
—
—
0
0
49
352
1.53
1.71
1.6
1.5
23.8
21.8
nmol/l
0.27
42
293
16
83
2.02
1.70
4.4
5.1
25.9
24.6
mmol/l
0.79
16
83
8
31
2.65
1.68
1.6
1.5
—
—
—
0
0
19
107
1.86
1.62
1.3
1.2
273.1
161.3
iu/ml
—
5
41
6
141
0.41
1.60
3.2
1.6
—
—
—
0
0
12
57
2.18
1.59
5.0
1.8
—
—
—
0
0
39
271
1.56
1.57
1.2
1.3
12.3
28.6
iu/ml
2.17
11
95
5
15
3.39
1.53
1.6
1.1
—
—
—
0
0
10
45
2.29
1.49
1.6
1.4
—
—
—
0
0
118
1029
1.40
1.39
5.5
2.9
62.3
45.1
u/l
0.75
111
965
5
17
2.99
1.36
1.0
1.0
—
—
—
0
0
8
35
2.34
1.28
1.6
1.1
—
—
—
0
0
6
25
2.45
1.25
1.5
1.4
—
—
—
0
0
6
25
2.45
1.25
1.5
1.4
—
—
—
0
0
6
25
2.45
1.25
1.3
1.6
—
—
—
0
0
152
1398
1.48
1.24
25.9
13.3
39.6
39.9
%
0.20
90
1055
51
394
1.41
1.21
5.4
3.9
0.0
0.0
estimate
0.00
19
132
14
80
1.81
1.16
2.3
1.4
—
—
—
0
0
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
88
749
1.33
1.13
4.8
3.7
0.0
0.0
estimate
0.00
16
130
5
21
2.42
1.09
1.0
1.1
—
—
—
0
0
5
21
2.42
1.09
1.0
1.1
—
—
—
0
0
5
21
2.42
1.09
1.0
1.1
—
—
—
0
0
7
35
2.04
1.01
1.6
1.1
—
—
—
0
0
86
740
1.30
0.99
6.9
5.1
0.0
0.0
estimate
0.00
20
134
5
23
2.21
0.98
2.0
1.6
—
—
—
0
0
67
562
1.30
0.92
5.6
3.8
—
—
—
0
0
18
119
1.57
0.92
2.6
2.9
66.2
64.2
ml/min/173m2
—
5
51
10
56
1.83
0.89
5.5
1.7
—
—
—
0
0
6
31
1.97
0.85
1.7
1.4
—
—
—
0
0
34
261
1.37
0.84
1.3
1.3
32.8
12.3
u/ml
0.49
12
102
30
226
1.39
0.83
2.6
2.7
4.5
2.7
e6/l
0.46
17
118
84
736
1.26
0.80
5.3
3.7
0.0
0.0
estimate
0.00
19
137
0
24
0.00
0.80
0.0
1.3
—
—
—
0
0
148
1391
1.31
0.75
9.2
5.2
45.7
39.2
mmol/mol
5.37
140
1299
5
24
2.11
0.75
1.2
1.5
—
—
—
0
0
5
26
1.95
0.71
1.0
1.0
—
—
—
0
0
10
61
1.68
0.70
4.4
2.8
58.3
49.9
%
—
10
61
5
91
0.54
0.69
2.0
1.5
—
—
—
0
0
5
27
1.87
0.69
1.0
1.2
—
—
—
0
0
5
27
1.87
0.69
1.6
1.4
—
—
—
0
0
24
181
1.37
0.67
11.0
7.0
—
—
—
0
0
30
239
1.30
0.60
2.7
2.5
0.9
0.9
e6/l
0.03
16
130
6
40
1.52
0.52
3.3
4.5
—
4.2
—
0
5
8
56
1.45
0.43
1.5
2.5
—
—
—
0
0
27
223
1.25
0.43
3.3
3.9
23.3
21.2
%
0.23
13
100
0
16
0.00
0.41
0.0
1.4
—
343.0
—
0
16
17
133
1.31
0.40
5.1
4.7
1.3
1.4
mmol/l
0.12
17
128
166
1615
1.26
0.39
16.6
9.6
31.4
25.2
u/l
0.54
158
1558
6
41
1.48
0.36
3.3
4.4
26.0
28.9
mg/l
—
6
33
6
41
1.48
0.36
3.5
4.4
25.3
45.3
mg/l
—
6
33
32
275
1.20
0.36
1.5
1.4
—
—
—
0
0
6
43
1.41
0.35
2.0
1.5
—
—
—
0
0
10
73
1.39
0.35
3.4
2.1
1.4
1.2
%
—
10
73
6
88
0.67
0.34
1.7
1.4
—
—
—
0
0
6
46
1.31
0.33
1.3
2.0
—
—
—
0
0
151
1468
1.15
0.28
5.4
4.3
6.6
5.9
mmol/l
3.39
135
1339
103
980
1.11
0.27
3.5
3.2
—
—
—
0
0
5
38
1.32
0.23
2.2
2.6
—
—
—
0
0
5
41
1.23
0.22
1.4
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
16.8
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
145
1416
1.11
0.19
23.7
11.7
80.7
82.0
ml/min/173m2
0.23
121
1146
131
1274
1.10
0.19
32.6
15.6
14.1
13.7
%
1.33
125
1256
6
52
1.16
0.19
1.0
1.5
—
313.9
—
0
31
6
53
1.14
0.19
1.7
1.2
—
—
—
0
0
6
53
1.14
0.19
1.7
1.2
—
—
—
0
0
7
61
1.15
0.18
1.9
2.2
26.0
40.5
u/l
—
7
55
9
79
1.15
0.15
3.0
1.8
—
—
—
0
0
9
82
1.10
0.15
2.0
1.8
—
—
—
0
0
27
291
0.92
0.12
1.4
1.6
—
—
—
0
0
149
1512
0.93
0.11
5.6
4.7
2.7
2.8
mmol/l
0.48
133
1398
16
175
0.91
0.09
1.2
2.2
—
—
—
0
0
147
1486
0.95
0.07
5.5
4.2
4.6
4.7
mmol/l
0.57
131
1377
9
86
1.05
0.07
1.1
1.0
—
—
—
0
0
11
102
1.08
0.03
2.3
1.9
—
—
—
0
0
16
159
1.01
0.00
1.2
2.0
—
—
—
0
0
142
1424
0.99
0.00
4.8
3.7
1.4
1.3
mmol/l
1.42
121
1304
147
1475
0.98
0.00
5.0
4.2
1.5
1.5
mmol/l
0.85
130
1361
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
6
60
1.00
0.00
3.8
3.0
6863.2
2285.3
u/ml
—
6
53
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
5.5
—
98.8
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
11.0
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
5.0
—
209.9
—
0
7
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
13.6
—
0
5
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_FACTITIALDERMAT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FACTITIALDERMAT | 1.852 [1.48, 2.32] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.356 |
During the follow-up period (1.1.1998 — 31.12.2019), 235 out of 821 females with L12_FACTITIALDERMAT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FACTITIALDERMAT | 2.697 [1.9, 3.82] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.02 |
During the follow-up period (1.1.1998 — 31.12.2019), 141 out of 347 males with L12_FACTITIALDERMAT died.
Mortality risk
Mortality risk for people of age
years, who have L12_FACTITIALDERMAT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.189% | 0.509% |
| 5 | 1.244% | 2.861% |
| 10 | 2.935% | 7.543% |
| 15 | 5.525% | 13.919% |
| 20 | 9.486% | 24.042% |
Relationships between endpoints
↥Index endpoint: L12_FACTITIALDERMAT – Factitial dermatitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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