neurotic excoriation: a condition in which patients produce skin lesions through repetitive, compulsive excoriation of their skin.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
191 |
4. Check minimum number of eventsNone |
191 |
5. Include endpointsNone |
191 |
6. Filter based on genotype QC (FinnGen only) |
185 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L98
- Name in latin
- Dermatitis artificialis
Similar endpoints
↥List of similar endpoints to
Factitial dermatitis
based on the number of shared cases.
Similar with more cases:
- Other disorders of skin and subcutaneous tissue, not elsewhere classified
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1738 | 1165 | 556 |
| Only index persons | 1405 | 982 | 423 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.02 |
| Only index persons | 0.03 | 0.04 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 54.96 | 55.45 | 53.93 |
| Only index persons | 53.35 | 54.22 | 51.35 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 185 | 131 | 54 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.02 |
| Median age at first event (years) | 48.78 | 47.82 | 51.11 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 191
- Matched controls
- 1910
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L98.1
ICD-10 Finland
Factitial dermatitis
+∞
196.3
153
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
7.6
37.1
68
130
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
8.9
34.5
50
73
D07AC01
ATC
betamethasone; topical
5.9
32.5
122
443
E0000UV, ,
ATC
6.1
32.1
135
538
D07AD01
ATC
clobetasol; topical
6.3
32.0
73
171
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.9
31.4
82
217
D07BA04
ATC
hydrocortisone and antiseptics; topical
8.0
30.9
49
79
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
81.4
25.6
28
*
S97
ICPC
Chronic ulcer skin
9.2
25.5
34
44
D07AC13
ATC
mometasone; topical
4.7
25.4
98
348
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
7.6
25.1
40
64
SPAT1148
SPAT
Treatment of chronic ulcer or burn
6.0
23.8
51
110
D07AB02
ATC
hydrocortisone butyrate; topical
4.4
23.1
95
349
F32.9
ICD-10 Finland
Depressive episode, unspecified
5.6
22.8
53
123
E000001, ,
ATC
4.7
22.6
73
223
69840
ICD-8 Finland
Pruritus and related conditions, Dermatitis factitia (artifacta)
+∞
22.3
21
*
J01FF01
ATC
clindamycin; systemic
4.4
22.1
87
308
L28.1
ICD-10 Finland
Prurigo nodularis
86.4
21.2
23
*
D09AB01
ATC
zinc bandage without supplements; topical
47.6
21.0
25
6
A10AB05
ATC
insulin aspart; parenteral
6.9
19.9
34
58
A46
ICD-10 Finland
Erysipelas
5.1
19.9
51
128
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
52.0
19.7
23
5
6984A
ICD-9 Finland
Pruritus and related conditions, Dermatitis factitia [artifacta][LICHENIFICATIO ET DERMATITIS ARTEFACTA]
+∞
18.0
17
*
D07BC01
ATC
betamethasone and antiseptics; topical
4.7
17.1
47
124
D07AA02
ATC
hydrocortisone; topical
4.2
16.7
56
172
D07CC01
ATC
betamethasone and antibiotics; topical
4.3
15.9
50
146
N05AH04
ATC
quetiapine; oral
3.9
15.6
58
191
L29.9
ICD-10 Finland
Pruritus, unspecified
17.0
15.4
24
16
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.1
14.9
49
147
J01CF05
ATC
flucloxacillin; systemic
6.0
14.7
28
53
C03CA01
ATC
furosemide; systemic
3.3
14.4
84
367
R06AE07
ATC
cetirizine; oral
3.2
14.1
113
592
A06AD11
ATC
lactulose; oral
4.1
13.8
45
134
D06AX01
ATC
fusidic acid; topical
4.6
13.4
36
92
A10AE04
ATC
insulin glargine; parenteral
4.8
13.3
33
79
N06AX16
ATC
venlafaxine; oral
3.7
13.2
52
176
E000002, ,
ATC
4.2
13.1
40
113
SPAT1262
SPAT
Handing over of treatment supplies
3.8
12.9
47
151
D07AB08
ATC
desonide; topical
4.1
12.6
40
116
N05AX08
ATC
risperidone; systemic
4.6
12.5
33
83
SPAT1240
SPAT
Therapeutic discussion
4.2
12.5
38
107
A10AC01
ATC
insulin (human); parenteral
4.7
12.3
31
75
R60.0
ICD-10 Finland
Localized oedema
4.0
12.2
40
119
M79.6
ICD-10 Finland
Pain in limb
2.9
12.0
106
572
N05BA04
ATC
oxazepam; oral
3.0
11.9
77
350
J01DC02
ATC
cefuroxime; systemic
5.6
11.8
24
48
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
5.1
11.6
26
57
N05BB01
ATC
hydroxyzine; systemic
4.8
11.5
28
66
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
11.4
74
336
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.8
11.4
22
42
TQW80
NOMESCO Finland
Local dermatologic skincare
15.1
11.2
18
13
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.3
11.1
32
86
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
13.0
11.1
19
16
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
5.4
11.1
23
47
103
Kela drug reimbursment
Diabetes, insulin-treated
3.0
11.0
68
299
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.3
11.0
31
82
Z00.8
ICD-10 Finland
Other general examinations
4.7
11.0
27
64
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
5.8
10.9
21
40
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.4
10.8
29
74
J01AA07
ATC
tetracycline; systemic
3.4
10.6
46
164
SPAT1301
SPAT
No procedures
2.8
10.5
80
393
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
25.0
10.4
14
6
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
5.1
10.3
23
50
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
5.3
10.3
22
46
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.0
10.2
61
262
S29
ICPC
Skin symptom/complaint other
3.1
10.2
55
223
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.8
10.1
24
55
A10AE05
ATC
insulin detemir; parenteral
5.6
10.1
20
39
L30.3
ICD-10 Finland
Infective dermatitis
9.6
10.1
20
23
J01MA02
ATC
ciprofloxacin; systemic
2.7
10.1
91
485
N05AA02
ATC
levomepromazine; systemic
9.2
9.8
20
24
N03AX16
ATC
[U] pregabalin
2.8
9.8
64
288
L20.0
ICD-10 Finland
Besnier prurigo
4.3
9.8
27
70
H3603, E103,
ICD-10 Finland
105.0
9.5
10
*
SPAT1260
SPAT
Consultation of another employee
3.0
9.5
51
206
SPAT1255
SPAT
Intravenous administration of medicine
4.7
9.4
23
54
SPAT1254
SPAT
Administration of medicine
3.2
9.4
43
158
P29
ICPC
Psychological sympt/compl other
4.3
9.3
26
68
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
7.8
9.0
20
28
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.2
8.8
41
152
L89
ICD-10 Finland
Decubitus ulcer and pressure area
52.4
8.8
10
*
L28.0
ICD-10 Finland
Lichen simplex chronicus
52.4
8.8
10
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
12.4
8.7
15
13
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
3.3
8.7
36
124
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
17.3
8.7
13
8
N05CF01
ATC
zopiclone; oral
2.5
8.6
80
425
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
4.5
8.5
22
54
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
7.7
8.5
19
27
A10AB01
ATC
insulin (human); parenteral
7.7
8.5
19
27
E000006, ,
ATC
4.3
8.4
23
59
Z2446
NOMESCO Finland
Social worker
4.4
8.3
22
55
EBA15
NOMESCO Finland
Extraction of multiple teeth
12.5
8.2
14
12
N05CD07
ATC
temazepam; oral
3.3
8.2
34
117
L28.2
ICD-10 Finland
Other prurigo
35.0
8.2
10
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
35.0
8.2
10
*
N05AH03
ATC
olanzapine; systemic
4.3
8.1
22
56
P76
ICPC
Depressive disorder
4.0
8.0
24
66
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.5
7.8
71
371
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
9.5
7.7
15
17
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.5
7.7
29
94
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
26.2
7.7
10
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.7
7.6
47
203
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
7.5
55
259
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.7
7.5
46
198
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
8.9
7.5
15
18
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.5
7.5
19
46
N03AG01
ATC
valproic acid; systemic, rectal
4.0
7.4
22
60
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.4
7.4
29
96
N06AX21
ATC
duloxetine; oral
3.0
7.3
37
143
J96.1
ICD-10 Finland
Chronic respiratory failure
16.6
7.3
11
7
N03AE01
ATC
clonazepam; systemic
4.1
7.3
21
56
SPAT1307
SPAT
Psychosocial counselling and guidance
4.4
7.3
19
47
P01
ICPC
Feeling anxious/nervous/tense
3.0
7.2
36
138
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
31.3
7.2
9
*
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
21.0
7.2
10
5
H36.00
ICD-10 Finland
Diabetic background retinopathy
21.0
7.2
10
5
T90
ICPC
Diabetes non-insulin dependent
2.6
7.2
53
250
J01DB01
ATC
cefalexin; oral
3.2
7.1
168
1322
NF1AA
NOMESCO Finland
Hip X-ray examination
3.4
7.1
27
88
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
14.5
7.0
11
8
N02AX02
ATC
tramadol; systemic, rectal
2.2
6.9
90
544
N06AB04
ATC
citalopram; systemic
2.5
6.8
54
262
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
41.6
6.8
8
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
41.6
6.8
8
*
R11
ICD-10 Finland
Nausea and vomiting
3.4
6.8
26
85
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.0
6.7
33
125
A28
ICPC
Limited function/disability NOS
2.7
6.7
41
176
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.3
6.6
26
86
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
10.6
6.6
12
12
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
10.6
6.6
12
12
N03AX12
ATC
[U] gabapentin; oral
2.6
6.6
46
210
I50.9
ICD-10 Finland
Heart failure, unspecified
2.8
6.6
36
145
D07XC01
ATC
betamethasone; topical
3.0
6.6
31
115
A10AE06
ATC
insulin degludec; parenteral
7.0
6.5
15
23
X59
ICD-10 Finland
Exposure to unspecified factor
2.5
6.5
46
212
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
8.6
6.4
13
16
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.6
6.4
42
186
WX892
NOMESCO Finland
Monitored bed care
3.7
6.3
21
62
N05AX12
ATC
aripiprazole; systemic
6.1
6.3
16
28
A10AA02, ,
ATC
6.1
6.3
16
28
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
27.7
6.3
8
*
U04
ICPC
Incontinence urine
4.0
6.2
18
48
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
6.2
28
101
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
6.2
55
280
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.6
6.2
21
63
A10AA01, ,
ATC
7.1
6.2
14
21
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
10.5
6.1
11
11
J01DA01
ATC
[U] cefalexin
2.2
6.1
131
947
SPAT1229
SPAT
Assessment of need for aid
3.5
6.1
22
69
H02AB04
ATC
methylprednisolone; systemic
2.7
6.1
36
151
S06.0
ICD-10 Finland
Concussion
2.9
6.1
30
114
N06AB06
ATC
sertraline; oral
2.9
6.1
31
120
P03
ICPC
Feeling depressed
3.1
6.1
26
91
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.7
6.0
20
59
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
112
622
2.94
11.99
8.8
3.6
34.49
35.80
g/l
1.47
104
585
77
355
2.96
11.56
2.7
2.0
3.66
2.93
mg/l
0.58
70
302
89
487
2.55
9.10
4.4
2.9
56.30
29.26
u/l
0.47
82
465
51
216
2.86
8.64
3.6
1.9
12.13
13.44
umol/l
0.50
46
195
52
227
2.77
8.30
2.9
1.7
—
—
—
0
0
46
191
2.86
8.04
3.9
1.9
2.41
2.40
g/l
0.02
40
175
57
275
2.53
7.36
1.8
1.7
1381.73
1072.34
nmol/l
1.06
46
204
33
120
3.12
7.25
6.3
2.7
1.90
2.15
mmol/l
0.15
28
88
42
179
2.73
6.93
4.1
2.0
19.26
22.24
%
0.71
30
153
81
469
2.26
6.85
4.5
2.4
43.77
58.47
u/l
4.65
74
434
105
677
2.22
6.81
14.0
10.6
1.10
1.25
inr
1.84
39
189
56
282
2.39
6.51
2.0
1.8
519.04
470.56
pmol/l
0.54
48
235
104
683
2.15
6.26
4.2
2.6
108.29
91.86
ug/l
0.45
94
622
74
431
2.17
6.02
2.6
1.9
182.57
183.09
u/l
0.00
68
409
74
435
2.14
5.85
5.5
3.5
32.10
8.92
mg/mmol
0.66
47
265
107
728
2.07
5.68
13.4
5.6
1.20
1.22
mmol/l
1.85
90
614
36
158
2.58
5.55
2.4
1.7
—
—
—
0
0
22
75
3.19
5.35
5.1
3.4
1.78
1.44
mmol/l
0.17
17
52
16
44
3.88
5.33
1.7
1.3
310.94
301.26
ug/g
0.05
11
24
23
81
3.09
5.30
7.5
3.2
5.35
4.97
kpa
1.35
23
75
26
100
2.85
5.15
2.0
1.4
—
—
—
0
0
35
161
2.44
4.87
2.3
1.7
—
—
—
0
0
99
680
1.95
4.86
10.7
5.0
1.20
1.22
mmol/l
1.70
90
611
44
225
2.24
4.82
4.1
3.0
0.81
0.81
mmol/l
0.00
39
215
36
170
2.38
4.73
2.9
2.7
6.22
7.65
umol/l
0.26
30
147
11
18
6.41
4.67
1.4
1.5
—
—
—
0
0
111
800
1.93
4.65
7.8
5.5
9.72
10.32
umol/l
0.32
105
757
62
367
2.02
4.64
1.6
1.2
0.86
1.19
u/ml
0.26
19
102
51
282
2.10
4.58
4.4
3.1
302.74
201.15
ng/l
0.18
34
206
79
515
1.91
4.44
3.8
3.0
2.34
2.36
mmol/l
0.66
62
451
30
136
2.43
4.30
3.8
3.3
—
—
—
0
0
94
654
1.86
4.27
2.8
2.2
74.79
76.70
nmol/l
0.29
88
579
145
1162
2.03
4.23
5.8
3.9
16.02
11.85
mm/h
2.41
134
1070
79
523
1.87
4.18
3.8
3.0
—
—
—
0
0
147
1195
2.00
3.96
5.4
3.9
14.52
14.72
pmol/l
0.36
133
1082
32
155
2.28
3.95
10.2
5.6
2.27
0.95
mmol/l
0.95
25
121
118
896
1.83
3.92
14.2
8.5
4.35
4.06
e9/l
0.68
109
784
22
92
2.57
3.72
2.7
3.1
4.36
4.56
pmol/l
0.18
17
81
24
106
2.45
3.63
19.3
5.0
13.80
8.15
mmol/l
1.97
24
98
34
175
2.15
3.63
1.8
1.6
1.49
1.39
%
0.25
24
152
59
371
1.85
3.58
3.0
2.5
10729.84
7900.18
umol/l
0.10
49
314
65
425
1.80
3.47
3.0
2.9
0.17
0.43
e6/l
1.35
52
317
12
32
3.93
3.45
2.7
1.4
—
—
—
0
0
10
23
4.53
3.36
3.6
2.3
59.60
57.57
%
—
10
23
65
429
1.78
3.34
3.2
2.7
3039.13
1187.18
ng/l
0.42
56
360
6
7
8.80
3.28
1.2
1.1
19.67
25.71
u/l
—
6
7
6
7
8.80
3.28
1.2
1.1
97.50
74.86
u/l
—
6
7
84
600
1.71
3.26
2.1
1.9
93.58
96.52
pmol/l
0.27
47
303
11
31
3.70
3.04
1.4
1.6
—
—
—
0
0
175
1564
2.42
3.01
32.6
14.0
3.98
3.96
mmol/l
0.72
169
1515
51
323
1.79
2.97
2.0
1.7
0.78
1.07
mg/l
0.87
34
259
15
58
2.72
2.95
2.5
1.8
—
—
—
0
0
143
1199
1.77
2.92
12.0
6.7
89.96
77.93
u/l
2.06
136
1114
9
22
4.24
2.92
1.4
1.4
—
—
—
0
0
6
9
6.84
2.89
3.5
3.4
162.00
107.00
nmol/l
—
6
9
55
363
1.72
2.77
2.8
2.1
—
—
—
0
0
78
567
1.63
2.72
4.3
3.6
72.67
41.42
ng/l
0.52
50
380
62
426
1.67
2.68
2.1
1.6
1.57
1.39
mmol/l
0.45
50
371
12
41
3.05
2.67
3.2
4.0
1.81
1.42
mg/l
0.62
12
36
93
709
1.61
2.66
3.7
2.4
—
—
—
0
0
14
57
2.57
2.51
4.9
1.8
—
—
—
0
0
172
1552
2.09
2.46
30.7
12.3
24.20
22.10
mg/l
0.41
149
1209
43
275
1.73
2.40
2.7
2.5
2.45
2.45
mmol/l
0.06
35
241
10
33
3.14
2.39
1.6
1.5
—
—
—
0
0
163
1450
1.85
2.36
6.9
4.6
1.94
1.87
mu/l
0.27
151
1316
11
40
2.85
2.31
1.1
1.0
—
0.91
—
0
7
7
21
3.42
1.98
1.9
1.6
—
—
—
0
0
7
21
3.42
1.98
1.9
1.6
—
—
—
0
0
6
16
3.83
1.95
1.0
1.0
—
—
—
0
0
51
359
1.57
1.95
1.6
1.5
22.96
21.50
nmol/l
0.20
44
301
17
87
2.05
1.86
7.8
4.9
26.23
24.56
mmol/l
1.12
17
87
5
12
4.25
1.83
1.8
1.3
—
—
—
0
0
11
47
2.42
1.81
1.5
1.4
—
—
—
0
0
7
24
2.99
1.74
1.7
1.6
—
—
—
0
0
6
146
0.39
1.73
3.2
1.6
—
—
—
0
0
5
13
3.92
1.72
1.0
1.2
—
—
—
0
0
20
112
1.88
1.72
1.4
1.2
273.14
151.62
iu/ml
—
5
44
40
274
1.58
1.71
1.2
1.3
12.27
28.32
iu/ml
2.11
11
95
23
136
1.79
1.68
2.9
2.4
24.67
30.67
u/l
0.41
18
117
12
56
2.22
1.65
5.2
1.7
—
—
—
0
0
122
1053
1.44
1.61
5.6
2.9
62.08
44.66
u/l
0.80
115
988
7
26
2.75
1.59
1.3
1.6
—
—
—
0
0
8
33
2.48
1.55
1.6
1.4
—
—
—
0
0
5
15
3.39
1.53
1.6
1.1
—
—
—
0
0
7
28
2.56
1.46
1.4
1.4
—
—
—
0
0
5
16
3.18
1.44
1.8
1.2
—
—
—
0
0
5
17
2.99
1.36
1.6
1.5
—
—
—
0
0
53
405
1.43
1.34
5.2
3.9
0.00
0.00
estimate
-0.00
19
136
5
18
2.82
1.29
2.2
1.8
—
—
—
0
0
8
36
2.27
1.26
2.1
2.0
131.00
128.59
g/l
—
8
22
6
25
2.44
1.25
1.7
1.4
—
—
—
0
0
8
37
2.21
1.23
1.6
1.1
—
—
—
0
0
5
19
2.67
1.22
1.0
1.2
—
—
—
0
0
5
19
2.67
1.22
1.0
1.2
—
—
—
0
0
8
38
2.15
1.20
1.6
1.2
—
—
—
0
0
6
26
2.35
1.19
1.0
1.0
—
—
—
0
0
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
5
20
2.54
1.16
1.6
1.4
—
—
—
0
0
90
768
1.33
1.12
4.8
3.7
0.00
0.00
estimate
-0.00
16
133
19
121
1.63
1.10
2.5
2.9
74.33
65.30
ml/min/173m2
—
6
50
5
21
2.42
1.09
1.6
1.5
—
—
—
0
0
14
82
1.76
1.08
2.3
1.4
—
—
—
0
0
32
232
1.46
1.07
2.6
2.7
4.22
2.80
e6/l
0.38
18
118
5
22
2.31
1.04
1.6
1.5
—
—
—
0
0
153
1419
1.39
1.03
9.2
5.2
45.85
39.24
mmol/mol
5.61
145
1324
88
759
1.30
0.98
6.8
5.1
0.00
0.00
estimate
-0.00
20
138
69
578
1.30
0.95
5.4
3.8
—
—
—
0
0
6
27
2.26
0.94
1.5
1.4
—
—
—
0
0
6
27
2.26
0.94
1.5
1.4
—
—
—
0
0
6
28
2.18
0.92
1.8
1.3
—
90.67
—
0
6
32
245
1.37
0.81
2.6
2.6
1.42
0.94
e6/l
0.33
17
130
34
263
1.36
0.80
1.3
1.3
32.76
11.87
u/ml
0.51
12
103
0
26
0.00
0.79
0.0
1.3
—
—
—
0
0
86
760
1.24
0.74
5.3
3.7
0.00
0.01
estimate
0.50
19
148
9
56
1.64
0.73
1.4
1.4
0.20
0.23
g/l
—
9
56
7
40
1.78
0.72
3.1
4.5
—
4.19
—
0
5
7
41
1.73
0.70
3.3
4.4
28.00
47.55
mg/l
—
7
33
7
41
1.73
0.70
3.1
4.4
28.07
29.83
mg/l
—
7
33
5
27
1.87
0.69
1.0
1.2
—
—
—
0
0
5
95
0.51
0.68
2.0
1.5
—
—
—
0
0
5
28
1.81
0.66
2.0
1.4
—
—
—
0
0
24
184
1.35
0.61
11.0
7.1
—
—
—
0
0
9
59
1.55
0.56
1.4
1.4
1.18
1.14
g/l
—
9
59
6
38
1.60
0.55
2.0
2.6
—
—
—
0
0
178
1730
1.42
0.54
41.7
18.3
39.37
39.91
%
0.65
161
1616
178
1731
1.42
0.53
41.3
18.4
4.39
4.45
e12/l
0.96
173
1681
171
1656
1.31
0.49
17.1
9.5
31.13
25.09
u/l
0.53
163
1597
28
229
1.26
0.47
3.4
4.0
22.15
21.35
%
0.08
14
105
7
50
1.41
0.45
1.4
1.9
—
—
—
0
0
6
91
0.65
0.43
1.7
1.4
—
—
—
0
0
8
58
1.40
0.42
1.5
2.4
—
—
—
0
0
11
81
1.38
0.37
3.0
1.8
—
—
—
0
0
33
284
1.20
0.36
1.5
1.4
—
—
—
0
0
6
45
1.34
0.34
2.0
1.5
—
—
—
0
0
151
1460
1.16
0.33
24.0
11.7
80.49
82.08
ml/min/173m2
0.30
127
1181
10
74
1.37
0.33
3.4
2.0
0.78
0.66
%
—
10
74
107
1014
1.13
0.31
3.6
3.2
—
—
—
0
0
7
56
1.26
0.30
1.0
1.5
—
323.16
—
0
33
10
76
1.33
0.28
3.4
2.0
1.42
1.19
%
—
10
76
155
1509
1.14
0.26
5.7
4.3
6.62
5.90
mmol/l
3.29
139
1376
27
303
0.87
0.22
1.4
1.6
—
—
—
0
0
5
41
1.23
0.22
1.4
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
16.82
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
140
1366
1.09
0.18
31.8
15.0
15.12
15.02
%
0.08
135
1351
7
63
1.12
0.17
1.9
2.2
26.00
40.45
u/l
—
7
57
6
55
1.09
0.09
1.7
1.1
—
—
—
0
0
6
55
1.09
0.09
1.7
1.1
—
—
—
0
0
9
86
1.05
0.07
2.0
1.8
—
—
—
0
0
17
183
0.92
0.07
1.2
2.2
—
—
—
0
0
154
1552
0.96
0.04
5.6
4.7
2.67
2.78
mmol/l
0.68
138
1434
152
1527
0.98
0.01
5.5
4.2
4.59
4.73
mmol/l
0.78
136
1415
147
1464
1.02
0.00
4.8
3.7
1.44
1.28
mmol/l
1.40
126
1339
11
106
1.04
0.00
2.6
2.4
—
16.05
—
0
8
17
166
1.03
0.00
1.2
2.1
—
—
—
0
0
11
107
1.03
0.00
2.1
1.9
—
—
—
0
0
152
1515
1.02
0.00
5.1
4.2
1.45
1.52
mmol/l
0.90
135
1398
6
60
1.00
0.00
3.8
3.0
6863.17
2285.62
u/ml
—
6
53
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
13.62
—
0
5
0
6
0.00
-0.00
0.0
5.5
—
98.83
—
0
6
9
90
1.00
-0.00
1.1
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.0
—
209.86
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
11.01
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_FACTITIALDERMAT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FACTITIALDERMAT | 1.852 [1.48, 2.32] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.356 |
During the follow-up period (1.1.1998 — 31.12.2019), 235 out of 821 females with L12_FACTITIALDERMAT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FACTITIALDERMAT | 2.697 [1.9, 3.82] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.02 |
During the follow-up period (1.1.1998 — 31.12.2019), 141 out of 347 males with L12_FACTITIALDERMAT died.
Mortality risk
Mortality risk for people of age
years, who have L12_FACTITIALDERMAT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.189% | 0.509% |
| 5 | 1.244% | 2.861% |
| 10 | 2.935% | 7.543% |
| 15 | 5.525% | 13.919% |
| 20 | 9.486% | 24.042% |
Relationships between endpoints
↥Index endpoint: L12_FACTITIALDERMAT – Factitial dermatitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data