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Pemphigoid

L12_PEMPHIGOID

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L12
  • Cause of death: ICD-10 L12

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

915

6. Filter based on genotype QC (FinnGen only)

915

Control definitions (FinnGen only)

Control exclude
L12_BULLOUS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L10-L14
Name in latin
Pemphigoides

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 915 469 446
Unadjusted period prevalence (%) 0.18 0.16 0.20
Median age at first event (years) 72.76 70.98 74.63

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
799
Matched controls
7992
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L12.0
ICD-10 Finland
Bullous pemphigoid
16384.0
323.0
633
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
15.2
208.9
394
479
L12.9
ICD-10 Finland
Pemphigoid, unspecified
+∞
177.9
164
*
D07AD01
ATC
clobetasol; topical
9.9
160.1
387
692
D07AC01
ATC
betamethasone; topical
6.1
121.4
509
1794
H02AB06
ATC
prednisolone; systemic
6.1
115.1
612
2789
L12.8
ICD-10 Finland
Other pemphigoid
+∞
87.1
82
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.5
86.3
313
835
E0000UV
ATC
NA
4.3
80.8
481
2090
L12.1
ICD-10 Finland
Cicatricial pemphigoid
+∞
67.7
64
*
L04AX01
ATC
azathioprine; systemic
11.2
63.3
125
130
J04BA02
ATC
dapsone; oral
69.5
61.4
70
11
TQW80
NOMESCO Finland
Local dermatologic skincare
12.5
54.1
100
90
L13.9
ICD-10 Finland
Bullous disorder, unspecified
69.3
50.9
58
9
135
Kela drug reimbursment
Pemphigus
+∞
50.5
48
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
49.8
422
2113
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
5.2
46.6
158
359
D07AC13
ATC
mometasone; topical
3.2
46.0
335
1483
L12
ICD-10 Finland
Pemphigoid
127.4
45.3
48
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
4.3
44.3
185
519
ECA20
NOMESCO Finland
Biopsy of gingiva
22.6
35.2
51
24
D07AB08
ATC
desonide; topical
4.1
34.5
148
418
L12.2
ICD-10 Finland
Chronic bullous disease of childhood
+∞
33.6
32
*
D07BC01
ATC
betamethasone and antiseptics; topical
3.6
31.4
162
533
E000001
ATC
NA
2.9
30.9
233
1001
D07AB02
ATC
hydrocortisone butyrate; topical
2.5
27.6
281
1420
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.8
25.5
197
845
XQ848
NOMESCO Finland
Dermatological photography
6.4
24.4
66
111
A02BC02
ATC
pantoprazole; systemic
2.2
24.2
558
4073
L29.9
ICD-10 Finland
Pruritus, unspecified
7.1
23.0
57
85
J01DB01
ATC
cefalexin; oral
2.4
22.7
651
5165
R06AE07
ATC
cetirizine; oral
2.1
21.2
350
2163
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
19.9
154
652
D02AX
ATC
Other emollients and protectives
6.5
19.4
51
83
L13.0
ICD-10 Finland
Dermatitis herpetiformis
102.4
18.6
20
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.9
18.6
62
135
C03CA01
ATC
furosemide; systemic
1.9
16.9
349
2291
H02AB07
ATC
prednisone; oral
2.5
16.9
153
703
EKA10
NOMESCO Finland
Biopsy of cheek
7.0
16.2
40
60
S18
ICPC
Laceration/cut
1.9
16.0
376
2570
S99
ICPC
Skin disease other
6.4
16.0
42
69
L13.8
ICD-10 Finland
Other specified bullous disorders
+∞
15.7
15
*
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
6.2
15.6
42
71
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.9
15.6
103
394
A10BH05
ATC
linagliptin; oral
3.4
15.4
78
248
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
15.2
403
2853
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.0
14.9
89
319
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
14.4
190
1035
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.0
14.4
58
153
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
5.1
14.4
45
92
L30.3
ICD-10 Finland
Infective dermatitis
4.7
14.3
48
106
A46
ICD-10 Finland
Erysipelas
2.2
14.2
156
785
S29
ICPC
Skin symptom/complaint other
2.2
14.1
165
852
L29.8
ICD-10 Finland
Other pruritus
9.1
14.1
29
33
D02AE01
ATC
carbamide; topical
3.3
13.9
73
239
K12.10
ICD-10 Finland
Stomatitis NOS
20.5
13.8
20
10
L12.3
ICD-10 Finland
Acquired epidermolysis bullosa
+∞
13.6
13
*
S97
ICPC
Chronic ulcer skin
3.0
13.5
82
296
J01FF01
ATC
clindamycin; systemic
1.9
13.3
225
1344
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
13.0
228
1380
A10AE04
ATC
insulin glargine; parenteral
2.5
12.9
103
441
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
12.8
164
875
A28
ICPC
Limited function/disability NOS
2.0
12.7
183
1025
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
12.3
155
823
L30.0
ICD-10 Finland
Nummular dermatitis
3.9
12.2
50
135
SBA00
NOMESCO Finland
Microbiological examinations
5.4
11.9
35
67
D09AB01
ATC
zinc bandage without supplements; topical
5.0
11.7
37
77
H13.3*L12.9
ICD-10 Finland
Ocular pemphigoid
+∞
11.5
11
*
L10.9
ICD-10 Finland
Pemphigus, unspecified
121.6
11.5
12
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.3
11.3
111
527
SPAT1229
SPAT
Assessment of need for aid
2.3
10.7
102
475
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.6
10.7
83
346
R06AE09
ATC
levocetirizine; oral
2.2
10.6
109
527
R06AX27
ATC
desloratadine; oral
1.9
10.6
171
994
J01AA07
ATC
tetracycline; systemic
2.3
10.5
101
474
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
10.4
70
271
L10.0
ICD-10 Finland
Pemphigus vulgaris
111.4
10.4
11
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
10.2
247
1639
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.8
10.2
67
256
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
10.1
256
1722
E000003
ATC
NA
3.5
10.1
47
142
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
10.1
233
1524
C07AB07
ATC
bisoprolol; oral
1.6
9.9
422
3267
T90
ICPC
Diabetes non-insulin dependent
1.8
9.9
209
1331
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.6
9.8
33
74
H02AB09
ATC
hydrocortisone; systemic
5.0
9.7
30
62
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
5.0
9.7
30
62
L04AA06
ATC
mycophenolic acid; systemic
6.5
9.6
24
38
L43.8
ICD-10 Finland
Other lichen planus
5.3
9.6
28
54
L28.1
ICD-10 Finland
Prurigo nodularis
8.5
9.6
20
24
SPAT1262
SPAT
Handing over of treatment supplies
1.8
9.5
171
1030
D07CC01
ATC
betamethasone and antibiotics; topical
2.1
9.5
108
546
XQ802
NOMESCO Finland
Epicutan test
3.9
9.4
38
102
L30.8
ICD-10 Finland
Other specified dermatitis
4.5
9.4
32
73
L51.19
ICD-10 Finland
Other bullous erythema multiforme
+∞
9.4
9
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
9.0
517
4273
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
8.9
184
1158
SPAT1254
SPAT
Administration of medicine
1.9
8.9
149
874
E000007
ATC
NA
2.9
8.8
51
181
SPAT1153
SPAT
Removal of sutures
1.6
8.8
268
1887
D07AA02
ATC
hydrocortisone; topical
2.1
8.7
108
564
A10BA02
ATC
metformin; oral
1.6
8.7
256
1782
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
8.7
244
1677
L43.1
ICD-10 Finland
Bullous lichen planus
50.5
8.7
10
*
E000002
ATC
NA
2.2
8.7
86
408
M05BA04
ATC
alendronic acid; oral
2.1
8.6
103
530
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
8.6
115
621
L10.2
ICD-10 Finland
Pemphigus foliaceus
+∞
8.3
8
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
5.6
8.3
23
42
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
8.3
182
1162
S17
ICPC
Abrasion/scratch/blister
4.2
8.2
30
74
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
8.1
159
979
XQ800
NOMESCO Finland
Prick test
2.8
8.1
51
191
L20.0
ICD-10 Finland
Besnier prurigo
3.1
8.0
43
146
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
7.9
226
1555
A07AA02
ATC
nystatin; oral
2.4
7.9
66
289
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.8
7.8
47
172
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.1
7.8
40
132
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
4.2
7.7
28
69
C08CA01
ATC
amlodipine; oral
1.5
7.7
321
2421
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.9
7.7
30
79
R53
ICD-10 Finland
Malaise and fatigue
1.7
7.7
181
1179
S02
ICPC
Pruritus
3.2
7.7
39
127
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.2
7.6
79
384
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.5
214
1464
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
7.4
156
981
N18.8
ICD-10 Finland
Other chronic renal failure
3.1
7.4
38
125
K13.78
ICD-10 Finland
Other change in the oral mucosa
4.4
7.4
25
58
L10.8
ICD-10 Finland
Other pemphigus
+∞
7.3
7
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
7.3
153
961
SPAT1263
SPAT
Sampling
1.5
7.3
323
2461
L43.9
ICD-10 Finland
Lichen planus, unspecified
4.3
7.2
25
60
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.1
7.1
76
377
R03AC02
ATC
salbutamol; inhalant
1.5
7.0
359
2815
A10BH02
ATC
vildagliptin; oral
3.6
6.9
29
82
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
6.9
68
326
E86
ICD-10 Finland
Volume depletion
3.1
6.8
35
116
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
6.8
57
253
E000006
ATC
NA
2.2
6.7
64
299
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
6.7
257
1886
A98
ICPC
Health maint/preventive medicine
1.7
6.6
693
6335
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.7
6.6
133
827
L50.9
ICD-10 Finland
Urticaria, unspecified
3.3
6.6
31
97
WX110
NOMESCO Finland
Local anesthesy
1.5
6.6
446
3693
SPAT1216
SPAT
Assessment of functional ability
1.7
6.5
151
975
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.9
6.5
25
66
WX892
NOMESCO Finland
Monitored bed care
2.2
6.5
67
324
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
6.5
245
1788
S21
ICPC
Skin texture symptom/complaint
1.9
6.5
104
597
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.5
6.5
49
205
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
6.3
6.5
16
26
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.2
6.5
31
98
C03AA03
ATC
hydrochlorothiazide; oral
1.9
6.5
97
547
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
6.5
124
758
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.5
6.4
235
1704
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
8.2
6.3
13
16
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.8
6.3
37
134
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.3
311
2407
205
Kela drug reimbursment
Chronic hypertension
1.5
6.3
279
2110
RS311
NOMESCO Finland
NA
26.9
6.2
8
*
L28
ICPC
Limited function/disability (L)
1.6
6.2
154
1013
H02AB04
ATC
methylprednisolone; systemic
1.8
6.2
114
687
K12.00
ICD-10 Finland
Recurrent oral aphthae
5.8
6.2
16
28
M04AA01
ATC
allopurinol; systemic
1.7
6.1
124
768
R06.0
ICD-10 Finland
Dyspnoea
1.5
6.0
203
1442

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
333
44
118.41
307.65
1.7
1.1
46.1
55.7
titre
—
23
7
269
316
11.64
222.68
1.4
1.2
—
—
—
0
0
636
3522
3.64
72.75
10.6
5.2
0.0
0.0
e9/l
0.85
592
3007
632
3507
3.59
71.59
10.6
5.2
0.6
0.6
e9/l
2.39
588
2983
644
3638
3.60
70.37
10.9
5.4
0.2
0.2
e9/l
4.34
599
3159
637
3586
3.56
69.74
10.7
5.3
1.7
1.8
e9/l
1.25
590
3120
590
3318
3.19
61.62
11.8
5.6
8.9
8.8
%
0.29
565
3073
588
3301
3.19
61.59
11.3
5.4
3.2
2.8
%
2.56
563
3043
578
3218
3.16
61.35
11.2
5.4
0.6
0.6
%
0.08
554
2973
481
2440
3.05
59.87
10.9
5.2
—
—
—
0
0
592
3378
3.13
59.43
11.6
5.6
24.5
26.1
%
2.86
565
3103
669
4121
3.32
58.15
12.7
8.3
4.6
4.3
e9/l
2.17
618
3590
582
3320
3.07
57.86
11.1
5.4
60.0
58.6
%
1.98
558
3073
201
614
3.91
57.36
2.5
1.9
349.7
384.9
nmol/l
1.47
184
548
133
334
4.49
49.11
1.3
1.2
570.7
185.2
u/ml
3.30
124
301
231
888
3.14
45.06
2.2
1.7
—
—
—
0
0
515
3517
2.06
24.92
5.3
4.6
33.7
34.6
g/l
3.38
466
3243
211
1039
2.34
23.63
3.6
2.5
2.0
1.8
%
1.29
194
919
312
1807
2.10
23.30
10.0
6.3
—
—
—
0
0
556
3986
2.01
22.53
7.2
6.6
1.2
1.2
mmol/l
1.18
463
3317
353
2177
2.01
21.91
2.7
2.2
3.2
3.2
mg/l
0.08
304
1830
719
5699
2.22
21.70
9.2
7.3
83.2
80.9
u/l
0.35
680
5277
381
2428
1.98
21.41
5.0
4.2
—
—
—
0
0
255
1415
2.11
20.97
7.1
4.4
—
—
—
0
0
142
619
2.53
20.61
1.5
2.5
—
—
—
0
0
170
806
2.36
20.53
1.4
1.3
502.4
471.0
titre
0.08
41
182
246
1358
2.11
20.44
1.3
1.2
1.2
1.5
u/ml
0.39
70
333
599
4513
1.95
19.76
5.3
4.7
7.3
6.8
mmol/l
3.52
565
4252
163
771
2.36
19.74
3.8
2.6
75.9
69.1
e9/l
1.43
130
608
544
3991
1.90
19.22
6.0
5.8
12.2
12.2
umol/l
0.01
511
3762
453
3143
1.87
18.99
15.4
9.9
0.0
0.0
e9/l
1.04
381
2567
174
865
2.25
18.68
1.8
1.4
—
—
—
0
0
155
744
2.30
18.05
1.6
2.8
65.8
66.0
g/l
0.09
142
662
210
1153
2.07
17.38
2.7
2.0
—
—
—
0
0
500
3660
1.81
16.88
6.7
5.7
1.2
1.2
mmol/l
0.78
444
3265
668
5362
1.91
16.50
5.2
4.1
16.1
14.6
mm/h
1.49
622
4848
227
1312
1.97
16.14
3.2
2.5
11.8
12.2
umol/l
0.30
214
1205
424
2999
1.77
15.69
2.6
2.2
80.4
78.4
nmol/l
0.64
375
2587
467
3421
1.75
15.08
2.5
2.1
95.1
93.3
pmol/l
0.33
257
1729
144
728
2.16
14.61
5.9
6.5
11.6
11.3
mmol/l
0.16
131
689
314
2081
1.77
14.20
1.8
1.6
18.6
20.6
nmol/l
1.39
265
1736
419
3020
1.71
14.00
3.4
2.8
140.1
144.6
ug/l
0.15
379
2724
284
1838
1.79
13.87
2.0
1.8
1244.9
1212.1
nmol/l
0.21
213
1357
627
5065
1.76
13.62
6.3
5.2
5641.4
2662.3
e6/l
0.46
12
98
206
1214
1.90
13.56
1.6
1.4
3.0
2.6
g/l
1.36
133
695
186
1062
1.94
13.46
5.8
5.1
1.1
1.0
mmol/l
0.54
162
971
71
271
2.76
13.33
1.6
2.5
38.3
36.6
g/l
1.56
64
224
379
2690
1.70
13.17
4.1
3.6
—
—
—
0
0
122
605
2.17
12.94
5.7
3.9
0.9
0.9
%
0.04
41
188
794
6960
2.06
12.55
26.5
17.1
25.6
26.5
mg/l
0.37
701
5721
384
2762
1.67
12.52
3.5
3.2
2284.8
1848.8
ng/l
0.71
333
2404
114
558
2.19
12.48
1.7
1.5
—
—
—
0
0
152
834
1.99
12.27
2.4
2.8
9.1
10.0
umol/l
0.15
133
722
114
565
2.16
12.08
5.0
4.0
0.2
0.1
%
0.13
39
170
624
5114
1.69
12.01
5.7
4.7
—
—
—
0
0
109
541
2.15
11.50
5.2
3.7
0.4
0.6
%
0.74
27
134
338
2410
1.64
11.05
5.2
3.8
7.4
7.4
ph
0.83
64
465
186
1134
1.80
10.76
3.3
2.5
21.4
21.8
%
0.13
153
961
58
224
2.70
10.67
1.2
1.2
0.3
1.7
u/ml
—
5
17
812
7284
2.02
10.38
29.6
20.5
138.9
139.5
mmol/l
6.46
792
7060
323
2309
1.62
10.29
3.4
3.2
283.3
344.1
mg/l
0.11
223
1470
116
619
2.00
10.06
1.6
1.5
—
—
—
0
0
812
7301
2.00
10.05
29.9
20.6
4.0
4.0
mmol/l
0.13
791
7068
192
1204
1.75
10.04
3.2
2.4
2.2
2.3
g/l
0.45
182
1106
133
747
1.91
9.94
1.6
1.7
—
—
—
0
0
443
3438
1.56
9.78
11.0
11.6
1.3
1.3
inr
0.20
116
966
132
745
1.90
9.71
2.3
2.2
0.2
0.2
g/l
0.27
119
696
809
7286
1.95
9.65
17.9
10.9
24.1
24.1
u/l
0.00
786
6961
84
403
2.19
9.63
1.7
1.7
1.2
1.5
g/l
0.81
79
364
741
6504
1.73
9.58
8.0
6.4
42.6
40.8
mmol/mol
4.45
684
5884
86
418
2.17
9.55
2.0
1.9
1.5
1.6
g/l
0.22
74
367
191
1220
1.71
9.29
32.3
30.8
1.4
1.4
inr
0.12
15
147
333
2453
1.56
9.08
4.2
3.9
18.1
9.2
mg/mmol
0.85
229
1555
324
2373
1.57
9.06
3.8
3.1
6.6
7.0
mmol/l
0.88
268
1928
369
2784
1.55
9.03
2.4
2.3
—
—
—
0
0
367
2773
1.54
8.88
3.4
3.3
2.3
2.4
mmol/l
0.21
304
2364
451
3565
1.52
8.83
4.7
4.2
0.0
0.0
estimate
0.00
81
683
453
3599
1.51
8.57
4.8
4.2
0.0
0.0
estimate
0.00
76
661
55
232
2.46
8.49
3.5
3.5
—
—
—
0
0
95
502
2.00
8.45
2.9
2.6
10.6
10.8
g/l
0.18
88
454
411
3208
1.51
8.41
4.9
4.2
170.1
53.7
ng/l
0.47
337
2450
822
7518
1.92
8.25
40.0
25.0
92.4
91.7
fl
3.73
807
7360
822
7519
1.92
8.23
40.1
25.1
247.7
241.3
e9/l
1.75
804
7284
822
7520
1.92
8.21
39.9
25.0
30.5
30.4
pg
0.70
807
7359
822
7520
1.92
8.21
40.1
25.1
4.3
4.4
e12/l
7.46
803
7254
822
7521
1.91
8.19
40.2
25.1
7.4
6.9
e9/l
6.49
805
7255
822
7522
1.91
8.17
40.5
25.3
128.4
131.9
g/l
8.34
807
7360
445
3554
1.49
8.01
6.3
5.7
0.0
0.0
estimate
0.00
82
672
755
6755
1.67
7.97
5.5
5.0
6.2
6.1
mmol/l
1.96
689
5988
317
2366
1.52
7.90
2.9
2.4
58.9
57.8
u/l
0.18
282
2171
614
5252
1.51
7.77
4.2
3.9
15.2
15.1
pmol/l
0.57
554
4624
123
728
1.80
7.73
4.3
6.0
1.6
1.4
mmol/l
1.28
115
697
322
2420
1.51
7.73
2.7
2.1
200.4
237.5
u/l
0.36
302
2257
156
990
1.69
7.67
4.7
6.3
1.2
1.3
mmol/l
0.24
104
770
187
1248
1.63
7.56
2.8
3.0
0.8
0.8
mmol/l
0.41
161
1147
253
1813
1.55
7.55
2.0
1.8
34783050.8
8041681.2
pmol/l
0.35
207
1455
717
6360
1.59
7.54
5.2
4.8
2.0
2.2
mu/l
0.44
656
5640
41
159
2.65
7.53
1.4
1.3
57.5
61.4
mmol/l
0.26
35
129
131
801
1.74
7.36
2.3
2.5
5.3
5.9
ug/l
0.23
103
685
96
534
1.89
7.35
5.7
4.0
0.0
0.7
%
0.60
27
144
47
198
2.45
7.30
1.1
1.7
—
—
—
0
0
782
7103
1.69
7.28
25.1
16.5
—
—
—
0
0
240
1715
1.54
7.21
4.3
4.1
—
—
—
0
0
154
992
1.66
7.14
4.8
6.3
5.0
5.1
kpa
0.42
138
945
154
993
1.66
7.11
4.8
6.3
12.1
11.6
kpa
0.37
138
946
130
804
1.72
7.00
3.6
3.5
1.8
2.1
mmol/l
0.30
111
638
61
296
2.14
6.84
2.5
2.2
412.9
552.3
ug/l
0.29
54
279
20
53
3.84
6.83
1.6
1.2
—
—
—
0
0
83
451
1.92
6.82
1.2
1.1
—
—
—
0
0
130
811
1.70
6.78
3.5
3.5
5.9
5.8
kpa
0.41
124
784
185
1263
1.58
6.75
1.8
1.9
29.8
30.0
s
0.11
180
1220
755
6836
1.60
6.67
5.2
5.3
2.5
2.6
mmol/l
2.16
683
6112
27
89
3.10
6.66
2.0
1.5
0.8
0.8
g/l
0.00
22
72
359
2825
1.45
6.58
4.9
4.0
177.2
131.6
e6/l
0.34
261
2097
635
5561
1.46
6.42
33.6
20.9
14.3
13.9
%
5.16
626
5432
109
658
1.75
6.39
3.8
3.8
124.0
93.1
ng/l
1.52
93
560
24
77
3.17
6.20
1.2
1.3
—
—
—
0
0
319
2480
1.44
6.14
4.3
3.5
358.4
105.3
e6/l
0.40
248
1968
110
679
1.70
5.96
2.9
2.9
4.4
4.4
kpa
0.01
103
654
733
6641
1.52
5.95
4.6
4.6
4.4
4.5
mmol/l
1.13
661
5979
38
162
2.40
5.80
1.4
1.2
11.8
2.9
u/ml
—
6
18
90
530
1.77
5.75
4.9
4.0
5.4
5.2
kpa
1.01
84
492
667
5950
1.45
5.68
29.6
18.8
37.9
38.4
%
0.53
406
3721
71
392
1.88
5.59
4.6
3.7
23.4
24.1
mmol/l
0.74
64
356
88
524
1.75
5.42
5.0
4.0
7.4
7.4
ph
1.68
13
61
67
372
1.86
5.20
2.3
1.7
0.8
3.5
ug/l
1.29
56
318
253
1935
1.43
5.18
3.5
2.8
6577.2
8824.4
umol/l
0.29
218
1617
277
2158
1.41
5.09
4.1
3.3
—
—
—
0
0
413
3440
1.37
5.04
4.6
4.2
—
—
—
0
0
288
2263
1.40
5.03
4.2
3.4
0.4
0.6
e6/l
0.68
223
1765
720
6571
1.45
4.96
4.5
4.6
1.4
1.5
mmol/l
0.21
646
5860
105
677
1.62
4.82
5.6
7.4
—
—
—
0
0
615
5478
1.37
4.76
36.3
23.0
329.5
331.1
g/l
4.08
607
5430
74
436
1.76
4.75
2.7
2.5
—
—
—
0
0
54
291
1.91
4.61
5.2
2.6
0.2
0.3
g/l
0.14
31
108
31
136
2.32
4.49
3.9
3.1
62.5
60.7
%
0.32
31
136
73
437
1.73
4.44
4.9
8.3
24.1
24.6
mmol/l
0.86
61
400
30
131
2.33
4.40
3.8
2.8
5.3
4.6
e9/l
0.74
30
131
62
355
1.80
4.39
1.4
1.4
—
—
—
0
0
13
35
3.75
4.37
1.3
1.8
11.2
15.6
%
—
6
16
204
1544
1.41
4.35
1.6
1.7
1.5
1.4
mg/l
0.50
161
1213
30
132
2.32
4.33
3.9
2.5
—
—
—
0
0
10
22
4.58
4.31
1.2
1.2
—
—
—
0
0
177
1308
1.44
4.30
3.4
3.2
2.7
2.3
e6/l
0.24
97
749
242
1889
1.38
4.30
4.5
4.0
84.8
85.1
%
0.07
235
1844
18
61
2.99
4.30
1.2
1.6
—
—
—
0
0
128
892
1.51
4.19
5.0
6.5
96.1
95.3
%
1.18
122
860
21
79
2.70
4.18
8.7
2.6
55.7
55.5
%
—
9
55
26
110
2.40
4.10
1.2
1.3
—
—
—
0
0
29
129
2.29
4.09
5.7
3.6
0.3
1.6
%
2.19
17
102
21
80
2.66
4.08
1.1
1.2
—
—
—
0
0
69
417
1.71
4.08
2.9
2.4
0.9
0.7
%
1.58
69
403
208
1600
1.39
4.01
5.8
4.2
207.2
261.5
ng/l
0.26
184
1372
23
93
2.51
3.99
1.3
1.3
124.7
102.8
u/ml
—
6
16
104
701
1.55
3.97
5.2
3.6
—
—
—
0
0
691
6341
1.37
3.97
4.2
4.1
1.3
1.3
mmol/l
0.65
616
5594
73
454
1.66
3.89
4.5
3.0
4.4
4.1
e9/l
0.36
52
324
55
316
1.79
3.88
5.4
4.8
25.0
25.0
mmol/l
0.07
50
296
297
2429
1.33
3.84
2.9
2.5
—
—
—
0
0
64
388
1.70
3.76
4.5
4.2
—
—
—
0
0
52
300
1.78
3.63
2.8
3.5
45.8
80.4
mg/l
0.80
38
235
13
40
3.28
3.63
1.7
1.6
—
41.4
—
0
8
208
1624
1.36
3.63
5.8
4.7
1.0
1.0
kg/l
0.69
32
239
52
301
1.77
3.60
2.8
3.5
31.2
50.0
mg/l
0.89
38
239
570
5126
1.30
3.52
4.5
4.3
—
—
—
0
0
13
41
3.20
3.50
1.1
1.1
—
—
—
0
0
224
1783
1.34
3.43
3.5
2.6
6.3
5.2
e6/l
0.62
205
1578
32
161
2.02
3.38
1.4
1.2
46.0
91.5
titre
—
5
13
247
1999
1.32
3.37
5.5
4.5
0.0
0.0
estimate
0.50
73
641
214
1707
1.33
3.22
3.7
2.9
515.0
550.3
mosm/kgh2o
2.34
190
1454
211
1680
1.33
3.21
3.4
3.1
2.5
2.5
mmol/l
0.78
183
1464
14
50
2.83
3.09
1.1
1.1
—
—
—
0
0
34
181
1.91
3.09
3.4
2.0
124.4
126.6
g/l
0.27
28
133
30
154
1.98
3.02
3.9
2.4
—
—
—
0
0
82
566
1.49
2.85
6.1
6.1
24.8
24.5
mmol/l
0.24
77
531
79
544
1.49
2.78
3.1
3.0
122.0
125.2
g/l
0.73
79
531
87
612
1.47
2.76
4.2
4.1
—
—
—
0
0
224
1835
1.29
2.75
2.6
2.4
—
—
—
0
0
97
700
1.43
2.70
2.7
2.1
240.1
151.4
ug/g
0.67
76
540
28
147
1.93
2.68
1.2
1.3
—
—
—
0
0
27
141
1.94
2.62
1.3
2.0
60.1
60.8
%
0.05
27
141
73
503
1.49
2.58
1.4
1.5
—
—
—
0
0
34
195
1.77
2.50
3.6
2.5
7.8
7.8
kpa
0.08
34
175
8
21
3.83
2.46
1.1
1.1
—
—
—
0
0
32
181
1.80
2.46
6.7
3.9
—
—
—
0
0
5
8
6.28
2.37
1.8
1.4
—
—
—
0
0
64
439
1.49
2.33
3.5
3.2
25.8
25.2
mmol/l
0.56
64
423
18
85
2.14
2.30
1.2
1.3
270.4
272.9
mosm/kgh2o
0.17
12
55
20
99
2.04
2.27
1.2
1.3
314.4
299.4
u/ml
0.05
14
56
7
18
3.91
2.25
1.6
1.4
—
—
—
0
0
41
256
1.63
2.25
5.1
5.6
1.2
1.4
mmol/l
0.52
36
224
45
288
1.59
2.24
2.4
2.1
—
—
—
0
0
63
435
1.48
2.23
6.5
8.4
—
—
—
0
0
19
93
2.07
2.22
4.7
4.0
—
—
—
0
0
31
184
1.71
2.06
2.3
2.5
—
—
—
0
0
7
21
3.35
1.96
1.3
1.1
76.2
143.1
iu/ml
—
7
21
92
699
1.35
1.94
5.3
3.7
1.2
1.2
mmol/l
0.57
86
597
59
416
1.45
1.91
2.1
2.5
—
13.5
—
0
10
35
220
1.61
1.90
2.0
3.7
—
—
—
0
0
103
802
1.32
1.85
5.0
4.6
—
—
—
0
0
69
506
1.39
1.81
4.2
3.5
—
—
—
0
0
124
993
1.29
1.81
1.2
1.3
—
—
—
0
0
99
774
1.31
1.74
1.4
1.3
—
—
—
0
0
25
148
1.71
1.72
2.2
1.5
—
—
—
0
0
19
105
1.83
1.64
1.6
1.1
—
—
—
0
0
39
262
1.51
1.63
4.0
3.4
0.8
0.9
nmol/l
1.06
32
208
7
26
2.70
1.58
1.0
1.0
—
—
—
0
0
17
92
1.86
1.56
1.1
1.2
—
—
—
0
0
7
27
2.60
1.51
2.4
1.9
532.6
1344.5
u/ml
—
7
27
6
21
2.87
1.50
1.0
1.6
3.8
11.0
nmol/l
—
6
16
6
21
2.87
1.50
1.8
1.1
—
—
—
0
0
34
227
1.52
1.48
1.6
1.5
—
—
—
0
0
7
28
2.51
1.45
1.0
1.1
—
—
—
0
0
42
297
1.43
1.40
1.3
1.4
—
—
—
0
0
11
53
2.09
1.39
1.1
1.2
—
—
—
0
0
298
2681
1.17
1.37
4.8
5.6
6.2
3.6
ug/l
0.31
268
2351
17
97
1.77
1.35
1.4
1.6
—
—
—
0
0
16
90
1.79
1.33
1.1
1.0
—
—
—
0
0
12
61
1.98
1.33
2.5
2.8
—
—
—
0
0
11
54
2.05
1.33
1.5
1.1
250.0
99.1
titre
—
6
11
48
352
1.38
1.32
5.0
4.1
—
—
—
0
0
15
83
1.82
1.32
1.3
1.1
—
—
—
0
0
58
439
1.34
1.31
4.0
4.3
—
—
—
0
0
126
1057
1.22
1.27
1.3
1.3
29.3
38.7
iu/ml
0.47
44
338
33
229
1.46
1.23
1.5
1.4
255.9
277.6
ug/g
0.16
14
127
27
180
1.52
1.22
1.2
1.2
—
—
—
0
0
26
172
1.53
1.21
3.0
2.4
—
—
—
0
0
15
86
1.76
1.19
1.7
1.2
—
—
—
0
0
99
817
1.24
1.18
4.1
3.1
224.1
246.7
ng/l
0.29
88
753
55
422
1.32
1.16
1.7
2.2
11.2
12.4
nmol/l
0.46
46
359
15
87
1.74
1.15
1.1
1.1
—
—
—
0
0
7
30
2.34
1.12
2.7
3.2
—
—
—
0
0
33
234
1.43
1.12
10.9
12.7
—
—
—
0
0
5
21
2.39
1.09
3.0
1.9
—
—
—
0
0
5
21
2.39
1.09
1.0
2.1
—
—
—
0
0
21
136
1.56
1.09
1.6
1.3
—
—
—
0
0
14
83
1.70
1.02
3.4
3.6
—
—
—
0
0
21
139
1.52
1.01
1.1
1.3
0.9
0.9
nmol/l
0.12
14
114
15
92
1.64
0.97
2.8
2.6
—
—
—
0
0
211
1897
1.15
0.97
4.9
4.0
—
—
—
0
0
14
85
1.66
0.94
1.9
2.1
—
—
—
0
0
6
27
2.23
0.93
3.2
2.3
—
—
—
0
0
6
27
2.23
0.93
1.0
1.0
—
—
—
0
0
32
235
1.37
0.92
7.5
4.5
7.4
7.4
ph
0.10
23
191
6
28
2.15
0.91
1.2
1.1
—
—
—
0
0
18
118
1.54
0.91
1.6
1.6
—
—
—
0
0
11
64
1.73
0.86
1.5
1.3
—
—
—
0
0
10
167
0.59
0.85
1.1
1.2
—
—
—
0
0
16
104
1.55
0.85
1.6
1.4
—
—
—
0
0
13
80
1.63
0.85
1.1
1.4
—
—
—
0
0
13
80
1.63
0.85
1.1
1.4
—
—
—
0
0
13
80
1.63
0.85
1.1
1.4
—
—
—
0
0
13
80
1.63
0.85
1.1
1.4
—
—
—
0
0
15
96
1.57
0.84
3.9
4.5
294.6
365.4
umol/l
—
10
85
8
45
1.78
0.84
2.1
3.1
—
—
—
0
0
10
57
1.76
0.84
1.0
1.7
—
—
—
0
0
10
59
1.70
0.76
1.0
1.1
—
—
—
0
0
256
2368
1.11
0.74
4.7
4.4
—
—
—
0
0
45
361
1.26
0.74
1.5
1.2
—
—
—
0
0
107
936
1.16
0.74
1.3
1.4
—
—
—
0
0
7
38
1.85
0.73
1.0
1.0
—
—
—
0
0
9
56
1.61
0.72
2.0
3.0
—
—
—
0
0
5
27
1.86
0.68
1.2
2.5
—
—
—
0
0
20
144
1.40
0.68
1.2
1.5
—
—
—
0
0
14
203
0.68
0.67
1.3
1.4
—
—
—
0
0
7
43
1.63
0.67
3.4
3.4
—
—
—
0
0
17
120
1.42
0.65
1.3
1.2
—
—
—
0
0
46
378
1.23
0.64
2.6
2.9
—
—
—
0
0
8
50
1.61
0.61
3.5
2.4
—
—
—
0
0
8
50
1.61
0.61
1.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
97.2
—
0
15
18
131
1.38
0.59
1.8
1.4
1203.2
1336.5
e6/l
0.07
12
92
25
193
1.30
0.58
8.8
4.9
3.3
2.7
mmol/l
0.37
18
136
72
627
1.16
0.56
1.5
1.4
—
—
—
0
0
6
37
1.63
0.55
1.3
1.2
4.4
6.3
ug/l
—
6
31
13
90
1.45
0.55
2.5
1.9
—
—
—
0
0
23
177
1.31
0.55
5.3
2.3
15.1
15.5
%
0.28
17
82
9
62
1.46
0.53
1.1
1.6
10.1
11.0
%
—
9
62
48
406
1.19
0.53
1.1
1.3
—
—
—
0
0
14
101
1.39
0.49
2.3
1.2
—
—
—
0
0
24
190
1.27
0.48
1.4
1.7
12821.9
19104.6
e6/l
0.56
18
138
7
46
1.53
0.48
2.0
1.8
—
—
—
0
0
11
76
1.45
0.48
1.3
1.3
—
—
—
0
0
7
48
1.46
0.47
39.4
15.1
—
—
—
0
0
5
81
0.62
0.46
1.2
1.1
—
—
—
0
0
20
156
1.29
0.45
1.4
1.7
—
—
—
0
0
7
50
1.40
0.45
1.0
1.8
—
—
—
0
0
99
898
1.11
0.44
3.5
3.8
3.9
26.3
ug/l
1.76
73
759
185
1973
0.92
0.44
3.1
3.2
—
—
—
0
0
8
57
1.41
0.42
1.3
1.1
—
—
—
0
0
8
57
1.41
0.42
1.1
1.2
—
—
—
0
0
27
222
1.22
0.41
1.1
1.2
—
—
—
0
0
14
105
1.34
0.41
1.6
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
5.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
22
177
1.25
0.40
1.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.2
1.1
—
—
—
0
0
15
115
1.31
0.39
1.6
1.4
28896.3
86744.3
e6/l
—
6
67
28
334
0.83
0.39
1.1
1.2
33.2
134.9
iu/ml
5.07
11
124
24
197
1.22
0.38
1.8
2.4
75.4
100.3
ug/min
0.19
11
122
27
321
0.84
0.36
3.0
3.4
156.7
65.7
u/ml
0.29
27
309
61
548
1.12
0.34
1.5
1.5
—
—
—
0
0
6
45
1.34
0.33
2.8
1.7
9.7
9.3
mmol/l
—
6
38
40
350
1.15
0.33
2.8
3.1
4.1
4.4
pmol/l
0.89
32
300
24
283
0.84
0.31
1.5
1.4
—
—
—
0
0
7
53
1.32
0.31
12.0
2.0
—
—
—
0
0
161
1524
1.07
0.30
2.8
3.3
1.0
0.8
ug/l
0.39
111
1056
177
1688
1.06
0.27
1.4
1.3
—
—
—
0
0
55
604
0.90
0.27
1.5
1.6
—
—
—
0
0
10
77
1.30
0.26
2.4
2.3
1.2
2.1
u/field
—
5
23
18
151
1.20
0.25
1.0
1.1
—
—
—
0
0
15
124
1.21
0.24
3.5
2.8
—
—
—
0
0
13
107
1.22
0.21
1.4
1.4
467.6
296.1
mu/l
1.04
13
97
5
42
1.19
0.21
3.2
2.0
—
781.2
—
0
18
0
11
0.00
0.21
0.0
2.3
—
16.7
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
13
156
0.83
0.21
1.3
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
10
123
0.81
0.20
1.5
1.5
—
—
—
0
0
6
51
1.18
0.19
1.3
1.3
—
—
—
0
0
11
90
1.22
0.19
1.3
1.2
—
0.7
—
0
7
107
1020
1.06
0.18
1.3
1.2
6.4
13.8
u/ml
1.12
44
348
7
59
1.19
0.18
1.1
1.2
—
—
—
0
0
8
68
1.18
0.16
1.1
1.2
—
—
—
0
0
9
82
1.10
0.15
1.2
1.2
—
—
—
0
0
9
83
1.09
0.14
1.3
1.2
—
—
nmol/l
—
0
0
9
110
0.82
0.13
4.0
2.5
—
—
—
0
0
31
287
1.08
0.12
1.5
1.5
—
—
—
0
0
28
260
1.08
0.11
5.4
5.5
—
—
—
0
0
5
44
1.14
0.10
1.8
1.2
—
—
—
0
0
6
54
1.11
0.09
2.7
2.5
—
—
—
0
0
6
57
1.05
0.08
3.0
2.0
4.8
2.0
ug/l
—
6
45
5
60
0.83
0.08
3.2
2.1
—
—
—
0
0
7
65
1.08
0.08
13.0
2.1
—
—
—
0
0
8
75
1.07
0.07
10.6
1.7
—
—
—
0
0
178
1809
0.98
0.07
1.8
1.6
1.3
1.3
mmol/l
0.06
161
1482
15
138
1.09
0.06
2.5
2.7
—
—
—
0
0
10
90
1.11
0.05
8.8
1.7
—
—
—
0
0
10
90
1.11
0.05
1.6
2.0
206.8
221.0
pmol/l
—
10
82
63
644
0.98
0.04
5.6
4.1
—
—
—
0
0
10
96
1.04
0.00
8.7
1.6
—
—
—
0
0
10
97
1.03
0.00
8.9
1.6
—
—
—
0
0
10
97
1.03
0.00
9.1
1.6
—
—
—
0
0
10
97
1.03
0.00
8.8
1.6
—
—
—
0
0
17
167
1.02
0.00
1.1
1.1
—
—
—
0
0
18
181
0.99
0.00
6.0
3.9
28.7
27.1
mg/l
0.05
11
118
10
101
0.99
0.00
1.6
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
6
69
0.87
0.00
1.5
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
69
0.87
0.00
1.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
3.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.1
—
0
6
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: L12_PEMPHIGOID – Pemphigoid

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).