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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Toxic liver disease with cholestasis, drug-induced

Endpoint Browser

TOXIC_LIVER_DISEA_W_CHOLESTA

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ATC codes for adverse effects of Drugs — ANY
  • Hospital discharge: ICD-10 — K71.0#

1 out of 7 registries used, show all original rules.

5

4. Check minimum number of events

None

5

5. Include endpoints

None

5

6. Filter based on genotype QC (FinnGen only)

5

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

All Female Male
Number of individuals 5 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 37.35 - -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5
34
+∞
0.51
14.4
14.0
13.4
13.6
%
—
5
34
0
15
0.00
0.51
0.0
1.3
—
—
—
0
0
0
15
0.00
0.51
0.0
4.7
—
—
—
0
0
5
40
+∞
0.24
8.8
13.0
140.8
139.6
mmol/l
—
5
40
5
41
+∞
0.24
9.0
12.6
3.9
4.0
mmol/l
—
5
41
5
44
+∞
0.00
9.6
10.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
5
42
+∞
0.00
4.4
3.6
6.8
6.0
mmol/l
—
5
42
0
5
0.00
0.00
0.0
4.0
—
96.1
—
0
5
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
5
44
+∞
0.00
14.6
14.4
89.8
81.7
umol/l
—
5
44
0
5
0.00
0.00
0.0
1.6
—
2.2
—
0
5
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
7.8
—
103.5
—
0
6
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
0.4
—
0
5
5
42
+∞
0.00
10.0
12.3
24.3
16.4
mg/l
—
5
34
5
45
+∞
-0.00
18.6
19.8
6.3
6.3
e9/l
—
5
45
5
45
+∞
-0.00
18.6
19.9
200.4
233.2
e9/l
—
5
45
5
45
+∞
-0.00
18.6
19.8
4.8
4.6
e12/l
—
5
45
5
45
+∞
-0.00
18.0
19.8
91.6
91.8
fl
—
5
45
5
45
+∞
-0.00
18.0
19.8
31.4
30.5
pg
—
5
45
5
45
+∞
-0.00
18.2
19.9
151.0
140.4
g/l
—
5
45

Mortality – FinRegistry

↥

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

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Index endpoint: TOXIC_LIVER_DISEA_W_CHOLESTA – Toxic liver disease with cholestasis, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).