No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
587 |
4. Check minimum number of eventsNone |
587 |
5. Include endpointsNone |
587 |
6. Filter based on genotype QC (FinnGen only) |
566 |
Control definitions (FinnGen only)
- Control exclude
- K11_LIVER
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K70-K77
- Name in latin
- Morbus hepatis toxicus
Similar endpoints
↥List of similar endpoints to
Toxic liver disease
based on the number of shared cases.
Similar with more cases:
- Diseases of liver
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3897 | 2092 | 1772 |
| Only index persons | 3296 | 1812 | 1484 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.05 |
| Only index persons | 0.06 | 0.07 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 56.47 | 57.86 | 54.71 |
| Only index persons | 55.21 | 56.21 | 53.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 566 | 332 | 234 |
| Unadjusted period prevalence (%) | 0.11 | 0.12 | 0.11 |
| Median age at first event (years) | 55.13 | 54.34 | 56.26 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 587
- Matched controls
- 5870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
+∞
295.6
258
*
K71.9
ICD-10 Finland
Toxic liver disease, unspecified
+∞
173.8
158
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
52.0
164.5
96
22
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
35.0
110.3
71
23
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
22.7
98.3
74
37
A05AA02
ATC
ursodeoxycholic acid; oral
31.7
90.7
60
21
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
7.4
90.2
155
270
K71.0
ICD-10 Finland
Toxic liver disease with cholestasis
+∞
87.7
82
*
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
+∞
86.6
81
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.7
72.9
167
380
K76.9
ICD-10 Finland
Liver disease, unspecified
188.6
65.5
67
*
L04AX01
ATC
azathioprine; systemic
7.9
46.7
68
96
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
12.1
45.4
47
42
K71.1
ICD-10 Finland
Toxic liver disease with hepatic necrosis
+∞
45.4
43
*
K71.6
ICD-10 Finland
Toxic liver disease with hepatitis, not elsewhere classified
+∞
36.9
35
*
L04AA06
ATC
mycophenolic acid; systemic
13.7
36.9
35
27
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
11.2
35.2
38
36
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.9
34.3
116
346
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
+∞
33.7
32
*
K70.1
ICD-10 Finland
Alcoholic hepatitis
+∞
32.6
31
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
27.7
218
1056
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
+∞
25.2
24
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.2
24.9
53
109
K72.9
ICD-10 Finland
Hepatic failure, unspecified
+∞
23.1
22
*
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
+∞
23.1
22
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
22.9
310
1887
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
21.7
165
773
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.7
21.5
41
76
A06AD11
ATC
lactulose; oral
3.0
21.2
111
428
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
+∞
21.0
20
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.6
20.4
40
76
H02AB06
ATC
prednisolone; systemic
2.2
20.2
318
2027
N05CF01
ATC
zopiclone; oral
2.3
19.8
234
1324
ZX120
NOMESCO Finland
Intravenous
3.3
19.5
83
283
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.8
19.3
63
181
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
21.7
18.8
27
13
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
196.0
18.6
19
*
L04AD01
ATC
ciclosporin; systemic
7.4
18.4
27
38
C10AC01
ATC
colestyramine; oral
6.0
18.2
33
58
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
18.2
224
1281
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
17.9
120
524
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
98.1
17.7
19
*
A07EA06
ATC
budesonide; oral, local oral
4.6
17.4
43
100
N02AX02
ATC
tramadol; systemic, rectal
2.1
17.3
287
1831
R50.9
ICD-10 Finland
Fever, unspecified
2.6
17.1
114
495
R94.5
ICD-10 Finland
Abnormal results of liver function studies
13.8
17.1
29
22
K71.3
ICD-10 Finland
Toxic liver disease with chronic persistent hepatitis
+∞
16.7
16
*
WX892
NOMESCO Finland
Monitored bed care
3.4
16.7
65
209
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.8
16.7
53
149
A02BC02
ATC
pantoprazole; systemic
2.2
16.4
421
3140
N07BB01
ATC
disulfiram; oral
4.0
16.1
48
129
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
16.0
97
401
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
13.4
15.8
27
21
Z94.4
ICD-10 Finland
Liver transplant status
87.5
15.6
17
*
UJK02
NOMESCO Finland
ERCP
6.1
14.9
26
44
N05AH04
ATC
quetiapine; oral
2.3
14.8
132
653
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
14.6
14
*
K74.3
ICD-10 Finland
Primary biliary cirrhosis
+∞
14.6
14
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
10.8
14.4
27
26
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
14.2
80
318
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.8
13.9
32
70
K83.0
ICD-10 Finland
Cholangitis
12.5
13.7
24
20
K75.2
ICD-10 Finland
Nonspecific reactive hepatitis
+∞
13.6
13
*
UJF32
NOMESCO Finland
Coloscopy
2.1
13.6
170
960
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
13.5
112
535
JJC00
NOMESCO Finland
Allogenic transplantation of liver
143.2
13.5
14
*
L04AX03
ATC
methotrexate; systemic
2.7
13.4
77
309
K92.0
ICD-10 Finland
Haematemesis
6.5
13.4
22
35
TK800
NOMESCO Finland
Hemodialysis
5.9
13.3
24
42
JN4AD
NOMESCO Finland
Body CT examination
2.8
13.2
72
281
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
12.9
230
1465
127
Kela drug reimbursment
Transplant complication
10.8
12.9
24
23
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
10.0
12.8
25
26
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
4.7
12.7
30
67
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
12.7
157
879
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
+∞
12.5
12
*
J01MA12
ATC
levofloxacin; systemic
2.2
12.4
121
617
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
12.4
107
519
H02AB04
ATC
methylprednisolone; systemic
2.3
12.3
103
493
N06AX11
ATC
mirtazapine; oral
1.9
12.3
217
1374
N05BA04
ATC
oxazepam; oral
2.0
11.9
175
1040
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
11.8
107
529
L04AA13
ATC
[U] leflunomide
4.7
11.8
27
59
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
11.7
83
368
C03CA01
ATC
furosemide; systemic
2.0
11.7
174
1038
P15
ICPC
Chronic alcohol abuse
4.5
11.6
28
64
N05CD07
ATC
temazepam; oral
2.4
11.5
83
372
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
11.4
71
296
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
11.3
85
388
N03AX16
ATC
[U] pregabalin
2.0
11.2
154
891
P01BA02
ATC
hydroxychloroquine; oral
2.7
11.1
63
251
N05BA01
ATC
diazepam; systemic, rectal
2.3
11.0
96
466
Z3231
NOMESCO Finland
Registered nurse
1.9
11.0
175
1063
C03DA01
ATC
spironolactone; oral
2.5
11.0
76
333
R53
ICD-10 Finland
Malaise and fatigue
2.0
10.8
157
924
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
61.1
10.7
12
*
K70.0
ICD-10 Finland
Alcoholic fatty liver
61.1
10.7
12
*
ZXD05
NOMESCO Finland
Urgent procedure
1.9
10.4
190
1205
R4110
NOMESCO Finland
Physiotherapy
1.9
10.3
175
1082
D97
ICPC
Liver disease NOS
23.9
10.3
14
6
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.7
10.1
55
214
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.9
10.1
50
185
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.5
10.0
67
289
J01FF01
ATC
clindamycin; systemic
1.9
9.9
167
1030
J01MA02
ATC
ciprofloxacin; systemic
1.8
9.7
224
1516
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
13.7
9.7
16
12
H02AB07
ATC
prednisone; oral
2.2
9.6
94
477
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.5
9.6
33
98
K71.8
ICD-10 Finland
Toxic liver disease with other disorders of liver
+∞
9.4
9
*
K76.89
ICD-10 Finland
Other specified diseases of liver
+∞
9.4
9
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.0
9.3
41
142
NH3EA
NOMESCO Finland
Feet X-ray examination with load
5.1
9.1
19
38
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
9.1
116
649
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.0
9.1
41
144
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
9.1
87
438
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.6
9.1
54
220
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.4
9.0
32
97
ZXE00
NOMESCO Finland
One hour or less
1.7
9.0
231
1606
L04AA01
ATC
[U] ciclosporin
8.1
8.9
19
24
K85
ICD-10 Finland
Acute pancreatitis
7.0
8.9
21
31
A02BC05
ATC
esomeprazole; systemic
1.7
8.8
243
1718
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
4.2
8.8
23
56
N06AB04
ATC
citalopram; systemic
1.9
8.7
133
792
M05BA04
ATC
alendronic acid; oral
2.5
8.6
55
232
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.9
8.6
25
66
N06AX16
ATC
venlafaxine; oral
2.1
8.6
93
491
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.8
8.5
26
71
B01AB05
ATC
enoxaparin; parenteral
1.7
8.5
186
1231
N05AX12
ATC
aripiprazole; systemic
3.3
8.5
32
101
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
13.0
8.4
14
11
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
8.4
84
430
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
8.4
84
430
TKC20
NOMESCO Finland
Catheterisation of bladder
2.7
8.4
47
186
JJ5AT, ,
NOMESCO Finland
+∞
8.4
8
*
K76.7
ICD-10 Finland
Hepatorenal syndrome
+∞
8.4
8
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
8.3
50
205
N05AH03
ATC
olanzapine; systemic
2.6
8.3
48
193
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
8.2
114
655
A10AB05
ATC
insulin aspart; parenteral
2.5
8.2
52
219
L04AD02
ATC
tacrolimus; systemic
11.9
8.1
14
12
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
9.1
8.1
16
18
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
8.1
57
252
ZY010
NOMESCO Finland
Hospital outpatient
2.7
8.0
43
166
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
8.0
46
184
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
7.4
8.0
18
25
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
8.0
67
319
L88
ICPC
Rheumatoid/seropositive arthritis
3.2
7.9
31
100
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.7
7.9
25
70
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.3
7.8
29
91
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
7.7
62
290
JJA20
NOMESCO Finland
Open biopsy of liver
45.6
7.7
9
*
AA1AD
NOMESCO Finland
CT of head and brain
1.8
7.7
151
965
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.8
7.7
23
62
WX002
NOMESCO Finland
Sedation and analgesia
1.9
7.7
116
685
WX882
NOMESCO Finland
High dependency care
4.1
7.7
21
53
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.8
7.7
38
141
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.9
7.6
36
130
L04AB04
ATC
adalimumab; parenteral
4.2
7.6
20
49
C07AA05
ATC
propranolol; systemic
1.8
7.5
126
769
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.3
7.5
28
88
A07EC01
ATC
sulfasalazine; oral, rectal
2.3
7.5
55
248
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
81.1
7.4
8
*
K83.1
ICD-10 Finland
Obstruction of bile duct
7.0
7.3
17
25
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.0
7.3
33
116
K71.4
ICD-10 Finland
Toxic liver disease with chronic lobular hepatitis
+∞
7.3
7
*
K71.7
ICD-10 Finland
Toxic liver disease with fibrosis and cirrhosis of liver
+∞
7.3
7
*
K71.5
ICD-10 Finland
Toxic liver disease with chronic active hepatitis
+∞
7.3
7
*
A07EC02
ATC
mesalazine; oral, rectal
2.6
7.3
41
163
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
7.4
7.2
16
22
M01CB01
ATC
sodium aurothiomalate; parenteral
7.4
7.2
16
22
N06AX12
ATC
bupropion; oral
2.5
7.2
46
194
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
7.2
236
1722
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.7
7.2
39
152
N05CF02
ATC
zolpidem; oral
1.8
7.1
109
646
N06AA09
ATC
amitriptyline; systemic
2.2
7.1
61
294
N17.8
ICD-10 Finland
Other acute renal failure
10.2
7.1
13
13
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.2
7.1
59
281
A41.9
ICD-10 Finland
Sepsis, unspecified
3.5
7.0
24
71
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
7.1
7.0
16
23
B18.2
ICD-10 Finland
Chronic viral hepatitis C
7.1
7.0
16
23
WW200
NOMESCO Finland
Immunization
3.8
7.0
21
57
SPAT1262
SPAT
Handing over of treatment supplies
1.9
6.9
99
575
L01BA01
ATC
methotrexate; systemic
3.1
6.9
28
93
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
6.2
6.8
17
28
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
6.7
54
253
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
22.8
6.7
9
*
P03
ICPC
Feeling depressed
2.2
6.7
56
267
N06AB05
ATC
paroxetine; oral
2.5
6.6
41
171
N06AB10
ATC
escitalopram; oral
1.7
6.6
123
773
WX730
NOMESCO Finland
Conventional respirator
10.2
6.6
12
12
A02BC01
ATC
omeprazole; systemic
1.7
6.5
157
1055
R06.0
ICD-10 Finland
Dyspnoea
1.7
6.5
152
1013
A11CC03
ATC
alfacalcidol; systemic
4.1
6.4
17
42
A28
ICPC
Limited function/disability NOS
1.9
6.4
90
519
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
6.4
61
307
C07AB07
ATC
bisoprolol; oral
1.6
6.3
266
2040
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.3
6.3
23
71
N02AA05
ATC
oxycodone; systemic
1.8
6.3
97
575
ZXE90
NOMESCO Finland
More than 22 hours
18.2
6.3
9
5
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
6.3
6
*
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
27.0
6.2
8
*
K92.1
ICD-10 Finland
Melaena
2.7
6.2
34
133
L40.5
ICD-10 Finland
Arthropathic psoriasis
5.1
6.2
18
36
N05AA02
ATC
levomepromazine; systemic
2.8
6.2
30
110
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.7
6.2
32
122
P76
ICPC
Depressive disorder
2.4
6.1
43
190
F05.9
ICD-10 Finland
Delirium, unspecified
4.2
6.1
16
39
J01DB01
ATC
cefalexin; oral
1.7
6.1
470
4126
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
12.7
6.1
10
8
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
6.1
88
511
SPAT1254
SPAT
Administration of medicine
1.9
6.1
81
458
ZXA10
NOMESCO Finland
Bilateral
1.8
6.1
106
652
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.7
6.1
33
129
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
6.1
55
271
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
6.0
56
278
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.8
6.0
29
106
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
5.6
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
112
16
86.27
210.44
1.2
1.1
—
—
—
0
0
231
366
9.76
152.13
3.6
2.0
0.19
0.22
g/l
4.32
213
347
195
258
10.82
148.14
1.5
1.8
1.23
1.60
g/l
0.67
186
239
213
319
9.91
146.52
2.4
2.9
10.50
10.14
g/l
0.57
206
294
102
69
17.68
118.07
4.6
2.4
37.86
30.35
umol/l
1.00
97
59
72
24
34.05
110.93
1.2
1.1
—
—
titre
—
0
0
90
58
18.15
106.52
2.0
3.6
1213.60
3153.00
u/ml
—
5
9
98
78
14.88
103.37
3.6
6.5
1177.25
205.50
iu/ml
—
8
10
220
522
6.14
93.90
7.0
2.4
27.08
7.38
umol/l
5.70
204
456
88
79
12.93
85.86
1.2
1.2
239.86
226.31
u/ml
0.12
58
47
89
82
12.61
85.40
1.2
1.2
—
—
—
0
0
369
1549
4.72
74.81
9.2
3.1
113.38
30.87
u/l
5.34
357
1474
77
72
12.16
72.90
1.4
1.3
90.48
111.60
u/ml
0.85
13
15
410
1898
4.85
72.00
9.4
4.3
34.39
36.09
g/l
7.53
395
1768
77
77
11.36
69.62
1.6
1.3
—
—
—
0
0
54
36
16.42
62.13
1.2
1.0
—
—
—
0
0
453
2421
4.82
61.57
15.3
5.7
23.35
10.95
umol/l
7.60
441
2297
246
932
3.82
53.55
1.6
1.4
2.46
2.25
g/l
0.99
194
563
84
139
6.89
50.06
1.2
1.2
—
—
—
0
0
271
1141
3.55
49.39
10.6
3.4
86.45
92.71
%
3.13
265
1112
180
579
4.04
49.17
3.0
2.3
26.79
22.77
%
2.05
160
506
313
1459
3.45
48.12
4.8
2.3
58.68
59.72
u/l
0.09
301
1358
385
2079
3.48
45.68
15.2
12.3
1.18
1.24
inr
0.83
123
609
177
622
3.64
41.72
3.2
2.2
2.34
2.37
g/l
0.32
165
579
379
2181
3.08
37.35
10.8
5.8
2.86
2.89
%
0.09
363
2049
136
431
3.81
37.02
4.8
2.2
49.65
32.33
u/l
0.69
122
366
179
681
3.34
36.68
3.3
2.2
14.59
13.45
umol/l
0.91
172
633
382
2246
3.01
35.48
10.8
5.9
27.26
28.39
%
1.12
366
2120
119
358
3.91
34.77
12.5
6.5
8.67
9.14
mmol/l
0.34
111
339
375
2219
2.91
33.75
10.3
5.7
57.39
56.83
%
0.37
361
2097
428
2725
3.11
33.50
16.2
9.0
4.18
4.00
e9/l
0.84
383
2384
511
3629
4.15
33.01
20.0
7.0
116.14
76.41
u/l
11.95
499
3404
33
28
12.43
32.78
1.1
1.2
—
—
—
0
0
134
462
3.46
31.73
5.5
4.4
263.81
253.01
u/l
0.24
127
437
149
576
3.13
29.00
3.0
1.8
1.69
1.46
%
3.38
132
513
342
2046
2.61
28.17
10.1
5.7
1.20
1.22
mmol/l
1.96
322
1865
29
27
11.25
27.08
1.6
1.7
—
—
—
0
0
361
2251
2.57
26.71
12.2
6.4
1.21
1.21
mmol/l
0.74
302
1920
459
3237
2.92
26.08
8.6
2.9
130.25
42.79
u/l
9.41
442
3040
161
709
2.75
24.25
6.1
3.3
0.80
0.83
mmol/l
1.41
155
676
124
478
3.02
23.88
3.9
2.6
2.11
1.78
%
1.65
109
430
236
1267
2.44
23.38
4.1
2.9
0.60
0.37
e6/l
0.57
181
943
281
1641
2.37
22.88
4.3
3.0
—
—
—
0
0
211
1100
2.43
22.07
3.1
2.1
2.63
3.11
mg/l
2.61
181
942
157
725
2.59
21.18
2.2
1.8
—
—
—
0
0
244
1377
2.32
21.09
4.3
3.0
50.68
108.05
e6/l
0.57
190
1051
132
562
2.74
20.93
10.0
5.2
1.05
1.04
mmol/l
0.11
126
526
323
2056
2.27
20.82
4.2
2.7
321.99
118.94
ug/l
2.34
297
1906
394
2730
2.35
20.62
9.4
4.5
6.64
6.62
mmol/l
0.07
374
2539
121
502
2.78
20.11
2.0
1.8
—
—
—
0
0
120
506
2.72
19.27
2.0
1.9
—
—
—
0
0
199
1069
2.30
18.92
1.3
1.2
0.98
1.72
u/ml
0.67
35
299
35
63
5.84
18.89
1.3
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
45
102
4.70
18.79
3.4
2.4
0.28
0.36
u/ml
0.83
25
57
31
23
14.16
18.44
6.0
1.7
100.84
100.74
%
0.00
31
23
85
317
2.97
17.07
1.7
1.6
—
—
—
0
0
28
20
14.64
16.96
2.1
2.4
225.07
70.42
umol/l
0.94
14
12
293
1897
2.09
16.88
3.3
2.2
76.50
76.18
nmol/l
0.07
274
1699
98
400
2.74
16.63
7.2
3.9
1.54
2.08
mmol/l
0.77
86
331
151
770
2.29
15.86
3.3
2.5
1.37
1.03
e6/l
0.46
84
425
175
951
2.20
15.73
3.3
2.4
6.28
5.77
e6/l
0.17
162
858
454
3529
2.26
15.40
7.0
4.0
16.44
11.30
mm/h
7.96
426
3256
142
715
2.30
15.31
3.5
2.7
2.74
2.17
e6/l
0.31
76
370
228
1399
2.03
14.68
2.8
2.0
137.00
226.36
u/l
1.12
216
1315
186
1059
2.11
14.68
1.7
1.5
19.34
21.42
nmol/l
1.03
167
899
56
183
3.28
14.02
1.9
2.0
1.31
1.52
g/l
0.83
48
164
330
2328
1.95
13.96
4.5
3.5
0.00
0.00
estimate
-0.00
69
462
156
860
2.11
13.21
5.5
3.7
277.15
425.75
ng/l
0.39
125
643
51
165
3.29
12.96
3.5
3.0
19.64
1291.93
u/ml
0.88
44
143
238
1545
1.91
12.55
4.6
3.2
2.34
2.36
mmol/l
0.57
208
1371
223
1425
1.91
12.27
4.9
3.1
7.79
7.69
mmol/l
0.09
185
1201
266
1810
1.86
11.95
2.3
1.9
98.05
96.59
pmol/l
0.15
134
912
325
2367
1.84
11.60
4.5
3.5
0.00
0.01
estimate
0.50
64
414
101
492
2.27
11.54
10.1
7.7
11.48
12.21
kpa
0.96
94
476
101
492
2.27
11.54
10.2
7.7
4.88
5.12
kpa
1.16
94
473
319
2333
1.80
11.01
5.8
4.8
0.00
0.00
estimate
0.50
67
431
32
85
3.92
10.89
4.6
3.3
3.73
4.06
e9/l
0.34
32
85
91
435
2.29
10.84
3.7
4.2
25.79
17.97
ug/l
0.12
78
354
98
488
2.21
10.58
10.3
7.8
1.21
1.12
mmol/l
0.08
67
398
138
783
2.00
10.55
2.0
1.7
1226.02
1211.13
nmol/l
0.05
110
590
32
88
3.79
10.39
5.0
3.7
54.66
56.13
%
0.22
32
88
43
150
3.01
9.65
7.4
3.2
1.67
1.49
mg/l
0.66
43
137
34
106
3.34
9.18
1.4
1.8
—
—
—
0
0
25
63
4.10
9.14
1.0
1.1
—
—
—
0
0
43
160
2.82
8.61
1.8
1.5
0.01
0.03
iu/ml
—
7
29
89
464
2.08
8.48
4.2
3.0
—
—
—
0
0
293
2198
1.66
8.37
3.9
2.5
—
—
—
0
0
42
162
2.72
7.87
3.4
2.0
—
—
—
0
0
57
258
2.34
7.67
1.9
1.7
—
—
—
0
0
533
4791
2.22
7.47
29.6
12.9
19.72
22.57
mg/l
1.72
477
3737
48
207
2.44
7.19
1.8
2.3
47.57
38.99
u/l
0.78
43
191
541
4910
2.30
7.09
31.0
14.7
139.08
139.71
mmol/l
6.37
530
4777
132
839
1.74
6.78
4.0
2.8
2.48
2.44
mmol/l
1.40
109
730
541
4928
2.25
6.72
31.4
14.8
3.95
3.97
mmol/l
1.12
530
4788
17
29
6.00
6.65
2.5
1.5
0.90
1.01
g/l
0.57
17
29
40
165
2.53
6.59
1.7
1.9
1.53
3.58
ug/l
0.56
35
150
194
1378
1.61
6.48
4.3
3.8
13.46
6.92
mg/mmol
0.61
118
858
163
1109
1.65
6.47
4.2
2.1
—
—
—
0
0
477
4186
1.74
6.43
35.2
15.5
14.82
14.81
%
0.01
471
4122
24
77
3.21
6.23
1.7
1.8
—
—
—
0
0
47
216
2.28
6.12
5.0
3.3
0.70
0.65
%
0.58
47
216
14
21
6.80
6.06
3.8
1.3
25.57
30.71
umol/l
1.03
14
21
35
141
2.58
6.06
3.7
2.1
84.23
92.49
%
0.84
35
135
56
280
2.11
5.94
1.6
1.4
—
—
—
0
0
154
1055
1.62
5.88
6.4
3.8
1.02
1.02
kg/l
0.38
21
141
13
19
6.97
5.76
2.9
2.9
46046.15
37431.84
ug/l
0.50
13
19
47
222
2.21
5.75
5.1
3.3
1.17
1.20
%
0.09
47
222
171
1217
1.57
5.52
3.1
2.6
4133.81
6696.43
umol/l
0.37
155
1059
29
112
2.67
5.47
1.6
1.7
—
—
—
0
0
28
107
2.70
5.39
1.7
1.8
—
—
—
0
0
16
34
4.81
5.33
1.2
1.1
—
—
—
0
0
16
34
4.81
5.33
1.2
1.1
—
—
—
0
0
36
157
2.38
5.30
3.8
3.6
1.61
1.26
mmol/l
1.32
36
152
25
91
2.82
5.27
1.6
1.2
—
—
—
0
0
25
91
2.82
5.27
1.6
1.2
—
—
—
0
0
16
35
4.67
5.21
1.2
1.1
—
—
—
0
0
16
35
4.67
5.21
1.2
1.1
—
—
—
0
0
16
35
4.67
5.21
1.2
1.1
—
—
—
0
0
230
1770
1.49
5.09
4.7
3.5
96.34
38.71
ng/l
0.58
156
1194
17
50
3.47
5.06
2.0
1.8
33.59
32.96
pg
0.21
17
50
57
305
1.96
5.04
3.6
3.6
4.34
4.55
pmol/l
0.72
49
271
23
82
2.88
5.03
1.7
1.4
—
—
—
0
0
490
4413
1.67
5.03
6.2
4.7
1.91
2.17
mu/l
0.45
462
4051
15
41
3.73
4.95
1.7
1.1
1.26
1.59
nmol/l
0.39
15
34
150
1063
1.55
4.86
2.3
1.7
1.58
1.08
mg/l
0.68
117
806
31
132
2.42
4.82
1.4
1.2
—
—
—
0
0
22
80
2.82
4.66
1.2
1.7
—
—
—
0
0
34
154
2.28
4.62
2.9
2.1
1328.73
2428.91
u/l
0.29
11
62
14
32
4.46
4.46
1.9
2.1
—
—
—
0
0
16
50
3.26
4.36
3.7
3.9
—
—
—
0
0
62
360
1.81
4.29
5.3
3.5
1.21
1.23
mmol/l
1.00
56
312
8
9
8.99
4.29
1.0
1.0
—
—
—
0
0
28
121
2.38
4.24
1.8
1.5
—
—
—
0
0
30
135
2.29
4.16
1.7
1.4
324.26
321.98
ug/g
0.02
22
79
131
931
1.52
4.13
1.8
1.7
143363367.81
11628337.75
pmol/l
0.44
113
774
21
81
2.65
4.01
1.7
1.7
—
—
—
0
0
21
81
2.65
4.01
1.7
1.7
—
—
—
0
0
169
1273
1.46
4.00
5.6
3.7
0.00
0.01
estimate
0.69
66
424
17
59
2.94
3.93
1.2
1.7
—
—
—
0
0
22
88
2.56
3.92
2.8
2.4
18.25
15.94
%
—
10
47
30
139
2.22
3.90
3.9
2.5
—
—
—
0
0
28
126
2.28
3.89
2.2
1.9
4.45
6.07
iu/l
—
9
43
16
55
2.96
3.76
1.4
1.1
—
—
—
0
0
165
1251
1.44
3.74
1.9
1.7
1.48
1.40
mmol/l
0.60
142
1067
30
142
2.17
3.71
1.3
1.3
446.14
230.04
miu/ml
—
7
73
413
3668
1.42
3.71
5.4
4.0
14.88
14.71
pmol/l
0.67
388
3346
22
91
2.47
3.68
3.0
2.2
134.12
128.51
g/l
0.40
17
68
29
136
2.19
3.67
1.7
3.5
36.53
89.83
mg/l
0.60
23
110
29
136
2.19
3.67
1.7
3.5
25.81
30.35
mg/l
0.60
23
110
6
6
10.09
3.50
1.0
3.8
—
—
—
0
0
227
1838
1.38
3.50
4.9
3.6
—
—
—
0
0
62
387
1.67
3.36
3.0
2.5
7.39
6.97
ug/l
0.08
54
344
543
5135
1.77
3.33
26.7
9.8
60.06
26.43
u/l
4.65
534
4957
14
48
2.96
3.32
1.6
1.8
—
—
—
0
0
15
54
2.82
3.27
2.1
1.7
—
—
—
0
0
31
158
2.02
3.20
1.2
1.1
—
—
—
0
0
31
158
2.02
3.20
1.6
1.9
—
—
—
0
0
31
158
2.02
3.20
1.2
1.1
—
—
—
0
0
17
67
2.58
3.15
1.5
1.7
—
—
—
0
0
354
3111
1.35
3.08
3.2
3.1
—
—
—
0
0
15
56
2.72
3.08
1.5
1.7
—
—
—
0
0
15
56
2.72
3.08
1.5
1.7
—
—
—
0
0
17
69
2.51
2.98
1.2
1.7
—
—
—
0
0
16
63
2.58
2.98
1.1
1.7
—
—
—
0
0
162
1270
1.38
2.96
2.8
3.1
1827.26
1072.66
ng/l
0.89
142
1066
6
9
6.72
2.87
1.2
2.0
—
—
—
0
0
13
49
2.69
2.64
2.1
1.7
—
—
—
0
0
487
4547
1.42
2.59
25.6
11.8
81.85
82.41
ml/min/173m2
0.20
428
3745
12
42
2.90
2.56
1.6
1.1
—
—
—
0
0
13
50
2.64
2.54
2.5
1.3
—
—
—
0
0
25
130
1.96
2.49
1.5
1.2
14.05
9.55
u/l
0.66
18
104
9
26
3.50
2.49
1.1
2.4
—
—
—
0
0
20
97
2.10
2.40
1.5
1.3
3.61
3.74
mmol/l
0.31
20
90
12
46
2.64
2.37
1.7
1.7
—
—
—
0
0
12
46
2.64
2.37
1.7
1.7
—
—
—
0
0
12
46
2.64
2.37
1.7
1.7
—
—
—
0
0
11
39
2.85
2.35
1.3
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
28
3.25
2.31
1.1
1.2
—
—
—
0
0
9
28
3.25
2.31
1.6
1.8
—
—
—
0
0
9
28
3.25
2.31
1.6
1.8
—
—
—
0
0
7
18
3.92
2.26
1.6
2.1
57.07
80.96
ug/l
—
7
18
21
107
2.00
2.23
1.3
1.4
—
—
—
0
0
10
35
2.89
2.21
24.6
17.2
1705.90
1697.17
nmol/l
—
10
35
6
14
4.32
2.15
1.2
1.5
167.50
73.86
nmol/24h
—
6
14
11
42
2.65
2.15
1.4
1.3
—
—
—
0
0
28
160
1.79
2.13
2.0
1.6
—
—
—
0
0
51
344
1.53
2.08
1.2
1.2
218.05
131.94
iu/ml
0.58
20
146
44
287
1.58
2.07
6.2
3.4
0.95
1.58
mmol/l
0.45
37
216
11
44
2.53
2.02
1.5
1.2
—
—
—
0
0
11
44
2.53
2.02
1.5
1.2
—
—
—
0
0
56
391
1.48
1.95
6.8
2.5
60.14
67.12
ml/min/173m2
0.53
21
162
23
128
1.83
1.92
1.8
1.3
—
—
—
0
0
6
17
3.55
1.84
1.0
1.1
—
—
—
0
0
7
23
3.07
1.80
1.1
1.3
—
—
—
0
0
20
110
1.85
1.75
1.6
1.3
529.05
443.43
mg/l
0.72
20
104
7
24
2.94
1.72
1.4
1.2
—
—
—
0
0
39
261
1.53
1.68
1.2
1.3
—
—
—
0
0
6
19
3.18
1.66
1.2
1.0
—
—
—
0
0
8
31
2.60
1.66
1.4
1.8
—
—
—
0
0
8
31
2.60
1.66
1.3
1.7
—
—
—
0
0
27
167
1.65
1.61
2.3
1.6
—
—
—
0
0
13
64
2.05
1.55
1.7
1.4
—
—
—
0
0
13
64
2.05
1.55
1.7
1.4
—
—
—
0
0
13
64
2.05
1.55
1.7
1.4
—
—
—
0
0
13
64
2.05
1.55
1.7
1.4
—
—
—
0
0
465
4408
1.26
1.52
7.1
5.5
40.40
39.62
mmol/mol
0.74
438
4127
6
21
2.88
1.51
1.0
1.9
—
—
—
0
0
13
65
2.02
1.49
1.7
1.4
—
—
—
0
0
6
22
2.74
1.43
1.0
1.9
—
—
—
0
0
19
111
1.74
1.40
1.7
1.4
—
—
—
0
0
7
29
2.43
1.39
1.4
1.4
—
—
—
0
0
19
112
1.72
1.37
2.2
1.8
—
—
—
0
0
5
17
2.96
1.36
2.6
1.9
—
—
—
0
0
5
17
2.96
1.36
2.6
1.9
—
—
—
0
0
10
47
2.15
1.34
1.1
1.3
—
—
—
0
0
485
4639
1.26
1.34
5.0
4.4
6.20
5.92
mmol/l
2.51
455
4258
27
176
1.56
1.34
2.7
1.8
—
—
—
0
0
17
98
1.76
1.32
1.8
1.3
218.58
151.10
e6/l
0.12
12
81
17
98
1.76
1.32
1.8
1.3
18.33
6.18
e6/l
0.45
12
79
32
218
1.49
1.31
1.5
1.3
22.38
26.00
iu/l
0.31
23
187
6
24
2.51
1.30
2.7
3.1
1817.83
851.00
u/ml
—
6
24
6
24
2.51
1.30
1.7
1.2
—
—
—
0
0
5
18
2.79
1.28
2.6
1.9
—
—
—
0
0
6
25
2.41
1.24
1.0
1.0
184.67
85.32
u/l
—
6
25
6
25
2.41
1.24
2.3
1.7
—
—
—
0
0
6
25
2.41
1.24
1.0
1.0
69.50
27.91
u/l
—
6
25
6
25
2.41
1.24
2.3
1.7
—
—
—
0
0
103
853
1.25
1.24
1.3
1.3
36.60
32.78
iu/ml
0.16
31
281
12
63
1.92
1.23
1.8
1.4
—
—
—
0
0
5
19
2.65
1.22
1.6
1.9
2.02
12.45
nmol/l
—
5
14
6
26
2.32
1.19
1.7
1.3
—
—
—
0
0
6
26
2.32
1.19
1.7
1.3
—
—
—
0
0
495
4764
1.25
1.17
5.2
4.4
4.70
4.72
mmol/l
0.13
468
4449
5
20
2.51
1.15
1.8
1.1
—
—
—
0
0
28
194
1.47
1.09
7.5
3.6
24.69
24.81
mmol/l
0.06
28
188
99
830
1.23
1.08
1.4
1.3
6.84
9.82
u/ml
0.31
34
328
12
202
0.59
1.03
1.7
1.5
—
—
—
0
0
7
35
2.01
1.00
1.1
1.1
—
—
—
0
0
491
4742
1.22
0.99
5.1
4.3
1.47
1.48
mmol/l
0.15
462
4413
9
50
1.81
0.97
2.6
2.2
—
—
—
0
0
6
27
2.23
0.93
1.0
1.8
—
—
—
0
0
6
30
2.01
0.87
1.5
3.3
—
—
—
0
0
17
113
1.52
0.83
1.7
1.5
38737.40
15069.76
e6/l
—
10
86
6
32
1.88
0.82
1.0
1.3
—
—
—
0
0
8
47
1.71
0.81
1.0
1.1
—
—
—
0
0
499
4850
1.19
0.79
5.8
4.8
2.71
2.80
mmol/l
1.44
475
4507
6
33
1.83
0.79
1.2
1.0
—
—
—
0
0
38
479
0.78
0.76
1.7
1.7
—
—
—
0
0
12
75
1.61
0.75
1.7
1.8
—
—
—
0
0
9
54
1.68
0.75
1.1
1.1
—
—
—
0
0
5
24
2.09
0.74
1.6
1.3
—
—
—
0
0
5
24
2.09
0.74
1.6
1.3
—
—
—
0
0
10
60
1.68
0.72
1.2
1.3
0.60
0.59
nmol/l
—
10
54
10
60
1.68
0.72
1.0
1.0
—
—
—
0
0
9
57
1.59
0.71
1.2
1.1
—
—
—
0
0
99
1124
0.86
0.71
3.7
4.1
23.58
21.37
%
0.60
40
510
58
484
1.22
0.70
2.2
2.0
—
—
—
0
0
18
127
1.43
0.68
1.2
1.4
—
—
—
0
0
64
545
1.20
0.64
2.3
2.1
—
—
—
0
0
546
5370
1.24
0.64
43.0
19.2
249.36
252.10
e9/l
0.40
530
5241
5
29
1.73
0.64
2.2
1.3
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
546
5374
1.23
0.60
42.9
19.2
4.39
4.51
e12/l
5.30
531
5232
546
5375
1.23
0.59
43.7
19.2
39.49
40.32
%
2.46
508
5062
17
123
1.39
0.58
1.5
1.3
—
—
—
0
0
546
5376
1.22
0.58
43.1
19.2
131.91
135.77
g/l
6.54
537
5302
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
98
876
1.14
0.55
1.3
1.5
—
—
—
0
0
8
124
0.64
0.55
1.6
1.4
—
—
—
0
0
8
124
0.64
0.55
1.6
1.4
—
—
—
0
0
89
792
1.15
0.54
1.5
1.4
—
—
—
0
0
7
47
1.50
0.47
1.1
1.6
14.32
17.45
ug/l
—
7
47
20
156
1.29
0.45
1.5
1.5
—
—
—
0
0
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
5
35
1.43
0.39
2.4
2.6
603.20
630.86
ml
—
5
21
5
37
1.35
0.37
1.2
1.2
284.40
173.31
pmol/l
—
5
37
9
124
0.72
0.35
1.6
1.4
—
—
—
0
0
9
124
0.72
0.35
1.6
1.4
—
—
—
0
0
6
46
1.31
0.33
6.5
3.6
120.90
52.75
u/ml
—
6
46
6
46
1.31
0.33
5.5
2.2
—
—
—
0
0
467
4589
1.09
0.33
4.8
3.9
1.37
1.29
mmol/l
1.38
438
4251
13
165
0.78
0.32
1.5
1.4
—
—
—
0
0
75
816
0.91
0.31
2.7
2.9
0.68
0.73
ug/l
0.23
46
506
10
130
0.77
0.29
1.7
1.5
—
—
—
0
0
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
16
131
1.23
0.27
1.2
1.1
—
—
—
0
0
5
71
0.70
0.26
1.0
1.4
—
—
—
0
0
25
216
1.16
0.26
2.6
1.9
—
—
—
0
0
132
1389
0.94
0.25
4.4
4.6
1.92
2.32
ug/l
0.59
121
1252
9
74
1.22
0.25
1.0
1.1
—
—
—
0
0
6
85
0.70
0.24
1.5
1.5
—
—
—
0
0
31
275
1.13
0.23
2.6
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.1
—
2.48
—
0
6
54
581
0.92
0.19
5.7
4.3
31.91
31.46
%
0.10
44
396
10
81
1.24
0.19
1.2
1.1
—
—
—
0
0
9
81
1.11
0.15
1.0
1.2
14.91
18.84
u/l
—
9
67
60
571
1.06
0.12
11.5
7.0
—
—
—
0
0
19
206
0.92
0.09
1.5
1.9
1.81
2.92
mg/l
1.36
14
155
5
60
0.83
0.08
1.0
1.2
—
—
—
0
0
13
140
0.93
0.04
1.4
1.4
—
—
—
0
0
11
101
1.09
0.04
1.6
1.7
170.27
223.23
pmol/l
1.19
11
94
16
168
0.95
0.02
2.4
1.8
—
—
—
0
0
25
249
1.00
0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
79
0.88
-0.00
1.4
1.7
—
—
—
0
0
6
68
0.88
-0.00
1.7
1.4
6.63
7.40
mmol/l
—
6
59
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
7.60
—
0
8
0
5
0.00
-0.00
0.0
4.8
—
60.30
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_TOXLIV and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_TOXLIV | 2.305 [1.95, 2.72] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.287 |
During the follow-up period (1.1.1998 — 31.12.2019), 482 out of 1710 females with K11_TOXLIV died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_TOXLIV | 3.07 [2.52, 3.74] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.036 |
During the follow-up period (1.1.1998 — 31.12.2019), 519 out of 1402 males with K11_TOXLIV died.
Mortality risk
Mortality risk for people of age
years, who have K11_TOXLIV.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.296% | 0.643% |
| 5 | 1.451% | 3.723% |
| 10 | 3.399% | 8.851% |
| 15 | 6.4% | 17.475% |
| 20 | 11.149% | 28.193% |
Relationships between endpoints
↥Index endpoint: K11_TOXLIV – Toxic liver disease
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data