Vitiligo: Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
444 |
4. Check minimum number of eventsNone |
444 |
5. Include endpointsNone |
444 |
6. Filter based on genotype QC (FinnGen only) |
421 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L80-L99
- Name in latin
- Vitiligo
Similar endpoints
↥List of similar endpoints to
Vitiligo
based on the number of shared cases.
Similar with more cases:
- Other disorders of skin and subcutaneous tissue
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3372 | 1868 | 1488 |
| Only index persons | 3076 | 1720 | 1356 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | 0.04 |
| Only index persons | 0.06 | 0.06 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 36.14 | 37.31 | 34.62 |
| Only index persons | 36.81 | 38.02 | 35.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 421 | 262 | 159 |
| Unadjusted period prevalence (%) | 0.09 | 0.09 | 0.07 |
| Median age at first event (years) | 44.70 | 43.18 | 47.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 444
- Matched controls
- 4440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L80
ICD-10 Finland
Vitiligo
13599.1
307.7
427
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.4
40.5
74
134
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
13.7
33.5
32
25
D07AD01
ATC
clobetasol; topical
3.6
26.5
108
367
D05AX02
ATC
calcipotriol; topical
7.0
23.4
37
57
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.0
22.1
125
512
E0000UV, ,
ATC
2.6
21.2
225
1266
70905
ICD-8 Finland
Other diseases of skin, Vitiligo
+∞
19.9
19
*
D07AC01
ATC
betamethasone; topical
2.5
19.7
195
1051
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
7.3
16.7
25
36
E03.89
ICD-10 Finland
Other specified hypothyroidism
5.7
15.2
29
54
H03AA01
ATC
levothyroxine sodium; systemic
2.3
12.6
116
587
TQW80
NOMESCO Finland
Local dermatologic skincare
8.8
10.7
22
26
104
Kela drug reimbursment
Thyroid insufficiency
3.3
10.4
40
128
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.7
10.3
58
231
L40.0
ICD-10 Finland
Psoriasis vulgaris
4.1
10.2
28
71
D02AX
ATC
Other emollients and protectives
4.9
9.9
22
47
D07AB08
ATC
desonide; topical
2.6
9.7
61
258
D07AC13
ATC
mometasone; topical
2.0
9.3
137
820
107
Kela drug reimbursment
Pernicious anaemia
8.9
8.9
18
21
B03BA03
ATC
hydroxocobalamin; parenteral
3.9
8.7
26
70
B81
ICPC
Anaemia vit B12/folate deficiency
4.7
8.7
20
44
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.4
8.7
64
291
H02AB07
ATC
prednisone; oral
2.4
8.6
65
299
L04AX03
ATC
methotrexate; systemic
2.6
8.4
52
218
E000001, ,
ATC
2.0
8.2
99
549
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.0
8.1
105
596
H02AB06
ATC
prednisolone; systemic
1.8
8.0
203
1427
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
8.0
137
855
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
7.9
55
244
L43.8
ICD-10 Finland
Other lichen planus
11.1
7.8
14
13
D02AE01
ATC
carbamide; topical
3.0
7.4
34
121
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
7.3
7
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
7.5
7.2
16
22
K29.4
ICD-10 Finland
Chronic atrophic gastritis
8.1
7.2
15
19
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
8.1
7.2
15
19
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
10.3
7.1
13
13
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
4.2
6.9
18
44
L04AA13
ATC
[U] leflunomide
5.8
6.8
18
32
L63.8
ICD-10 Finland
Other alopecia areata
17.0
6.8
10
6
D07XC01
ATC
betamethasone; topical
2.3
6.8
54
254
J31.0
ICD-10 Finland
Chronic rhinitis
2.4
6.7
49
221
J02AC01
ATC
fluconazole; systemic
1.7
6.6
180
1273
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.8
6.4
19
51
L28.0
ICD-10 Finland
Lichen simplex chronicus
14.6
6.4
10
7
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
6.3
36
145
P01BA02
ATC
hydroxychloroquine; oral
2.5
6.3
41
176
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.0
6.3
27
93
L94.0
ICD-10 Finland
Localized scleroderma [morphea]
+∞
6.3
6
*
7090F
ICD-9 Finland
Other disorders of skin and subcutaneous tissue, Dyschromia[VITILIGO]
+∞
6.3
6
*
D05BA02
ATC
methoxsalen; oral
+∞
6.3
6
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.1
6.2
26
88
H02AB04
ATC
methylprednisolone; systemic
2.1
6.2
60
305
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
4.2
6.1
16
39
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
70
285
2.73
12.02
1.4
1.2
204.83
162.05
iu/ml
0.32
28
126
38
125
3.23
9.49
3.9
1.8
—
—
—
0
0
145
880
1.96
9.45
1.4
1.3
0.71
1.96
u/ml
1.56
30
237
20
44
4.71
8.67
2.4
4.0
58.29
49.06
u/ml
—
7
14
214
1545
1.74
7.56
7.8
6.5
1.22
1.22
mmol/l
0.66
183
1332
340
2822
1.87
7.23
5.6
3.7
14.89
14.54
pmol/l
1.88
315
2593
179
1265
1.70
6.59
1.9
1.8
96.51
95.68
pmol/l
0.07
91
656
194
1402
1.68
6.55
2.8
2.2
75.87
75.48
nmol/l
0.07
181
1278
25
80
3.25
6.54
1.0
1.3
—
0.96
—
0
5
13
16
8.33
6.37
1.0
1.2
—
—
—
0
0
227
1728
1.64
6.14
8.7
5.7
28.57
28.85
%
0.16
219
1639
386
3397
2.04
6.14
6.3
4.3
1.87
1.83
mu/l
0.29
371
3146
224
1710
1.63
5.91
8.5
5.5
56.21
56.60
%
0.21
216
1619
119
773
1.74
5.84
2.4
2.1
3.02
2.87
mg/l
0.25
103
666
316
2679
1.62
5.00
8.3
7.0
76.22
76.55
u/l
0.05
308
2520
23
85
2.80
4.75
1.0
1.2
—
—
—
0
0
312
2652
1.59
4.74
5.3
3.8
10.11
10.23
mm/h
0.07
295
2461
15
36
4.28
4.55
1.0
1.4
—
—
—
0
0
186
1420
1.53
4.54
6.9
5.7
1.22
1.22
mmol/l
0.38
171
1304
182
1389
1.53
4.42
11.7
9.3
1.23
1.13
inr
0.58
40
425
251
2051
1.51
4.40
10.9
9.2
3.72
3.98
e9/l
1.47
231
1797
67
405
1.77
4.15
2.7
2.0
21.41
23.84
%
0.98
59
361
8
11
7.38
3.87
1.1
1.1
88.50
94.82
%
—
8
11
78
511
1.64
3.60
1.5
1.6
1006.99
1156.84
nmol/l
0.83
57
387
92
634
1.57
3.44
1.3
1.3
22.42
8.92
u/ml
0.52
34
257
213
1740
1.43
3.42
5.1
6.0
11.08
10.97
umol/l
0.04
207
1658
10
23
4.42
3.33
1.5
1.3
—
—
—
0
0
11
28
4.00
3.31
1.0
1.1
—
94.40
—
0
5
151
1169
1.44
3.20
3.6
2.9
—
—
—
0
0
12
35
3.49
3.13
1.2
1.1
—
—
—
0
0
12
35
3.49
3.13
1.2
1.1
—
—
—
0
0
360
3274
1.53
3.05
5.4
4.9
39.19
38.90
mmol/mol
0.23
334
3073
13
45
2.95
3.05
1.3
1.4
—
—
—
0
0
12
36
3.40
3.04
1.2
1.1
—
—
—
0
0
12
36
3.40
3.04
1.2
1.1
—
—
—
0
0
12
36
3.40
3.04
1.2
1.1
—
—
—
0
0
92
654
1.51
2.98
1.3
1.3
23.98
27.60
iu/ml
0.17
29
222
200
1644
1.39
2.97
3.3
2.6
100.60
110.35
ug/l
0.33
185
1537
394
3667
1.66
2.91
14.6
11.7
18.32
21.34
mg/l
1.37
321
2840
136
1052
1.42
2.85
2.3
2.4
57.97
61.69
u/l
0.33
126
984
119
905
1.43
2.72
3.6
2.8
0.20
0.38
e6/l
1.20
90
676
97
715
1.46
2.61
1.5
1.4
20.05
21.07
nmol/l
0.32
83
610
20
94
2.18
2.59
3.4
2.1
13.56
11.52
mg/l
0.52
20
88
12
42
2.91
2.56
2.7
2.2
—
—
—
0
0
226
1927
1.35
2.55
4.9
4.5
6.88
6.51
mmol/l
1.36
207
1775
85
615
1.47
2.52
1.7
1.7
428.49
447.69
pmol/l
0.29
73
537
9
26
3.51
2.49
2.1
2.1
—
—
—
0
0
12
45
2.71
2.47
1.3
1.2
—
—
—
0
0
47
301
1.63
2.39
3.1
4.5
3.20
21.52
ug/l
0.71
39
248
70
493
1.50
2.37
2.2
3.7
0.82
0.81
mmol/l
0.07
64
471
109
847
1.38
2.17
2.3
2.5
336.76
5343.20
umol/l
2.85
101
760
413
3938
1.70
2.17
11.7
9.2
25.28
27.14
u/l
1.75
406
3812
59
409
1.51
2.16
4.4
4.0
31.42
31.45
%
0.01
43
283
29
169
1.77
2.09
1.3
1.7
—
—
—
0
0
84
630
1.41
2.05
2.0
2.2
—
—
—
0
0
17
83
2.09
2.04
1.2
1.1
—
—
—
0
0
76
562
1.43
2.01
1.9
2.1
—
—
—
0
0
300
2724
1.31
1.93
3.7
3.4
—
—
—
0
0
18
92
2.00
1.93
1.3
1.4
241.84
317.71
ug/g
0.79
12
47
202
1743
1.29
1.92
3.5
3.2
0.00
0.00
estimate
0.50
33
356
202
1745
1.29
1.89
4.8
4.4
0.00
0.00
estimate
-0.00
34
336
35
222
1.63
1.88
6.5
3.1
114.12
69.09
ng/l
1.46
29
202
371
3484
1.39
1.84
4.2
4.0
5.92
5.84
mmol/l
0.40
347
3228
6
17
3.56
1.84
1.0
1.1
—
—
—
0
0
6
17
3.56
1.84
1.0
1.1
—
—
—
0
0
9
35
2.60
1.81
1.3
1.1
—
—
—
0
0
34
217
1.61
1.79
1.6
1.4
—
—
—
0
0
203
1764
1.28
1.79
3.6
3.2
0.00
0.00
estimate
-0.00
33
321
54
383
1.47
1.79
2.5
2.5
6.77
7.55
umol/l
0.13
49
322
6
18
3.36
1.75
1.0
1.1
—
—
—
0
0
6
18
3.36
1.75
1.0
1.1
—
—
—
0
0
24
141
1.74
1.72
1.7
1.5
—
—
—
0
0
70
527
1.39
1.68
2.8
2.5
1.01
0.94
e6/l
0.06
39
289
5
14
3.60
1.62
4.4
1.6
—
—
—
0
0
15
77
1.98
1.61
1.1
1.4
—
—
—
0
0
98
784
1.32
1.60
2.3
2.9
635.08
856.46
ng/l
0.77
80
653
100
803
1.32
1.59
2.1
2.2
—
—
—
0
0
33
216
1.57
1.59
2.1
2.4
4.85
7.82
ug/l
0.80
28
194
385
3661
1.39
1.56
15.5
12.7
139.65
139.68
mmol/l
0.10
380
3563
66
502
1.37
1.50
2.9
2.7
1.70
3.02
e6/l
1.22
35
268
12
59
2.06
1.45
1.6
1.2
1.40
2.67
u/ml
—
5
21
12
59
2.06
1.45
1.7
1.2
4.17
3.86
u/ml
—
6
28
5
16
3.15
1.44
1.2
2.3
—
—
—
0
0
5
16
3.15
1.44
1.2
1.1
66.40
95.87
u/l
—
5
16
5
16
3.15
1.44
1.2
1.1
10.40
33.76
u/l
—
5
16
5
16
3.15
1.44
1.2
2.3
—
—
—
0
0
33
222
1.53
1.43
1.1
1.0
—
—
—
0
0
21
126
1.70
1.42
1.8
1.6
—
—
—
0
0
17
96
1.80
1.41
1.9
1.9
1.91
6.34
iu/l
—
6
35
10
46
2.20
1.41
1.1
1.1
—
—
—
0
0
11
53
2.10
1.39
2.6
1.9
12.81
13.18
%
0.57
11
53
6
23
2.63
1.37
8.7
2.5
—
—
—
0
0
62
476
1.35
1.34
1.7
1.9
—
—
—
0
0
429
4184
1.75
1.33
22.5
17.2
40.45
40.61
%
0.26
411
3965
22
137
1.64
1.32
1.3
1.4
—
—
—
0
0
5
18
2.80
1.29
4.8
2.8
37800.00
38138.89
ug/l
—
5
18
37
262
1.45
1.28
6.8
9.7
123.70
123.08
g/l
0.07
37
255
183
1619
1.22
1.27
2.4
2.5
—
—
—
0
0
12
63
1.93
1.24
1.1
2.0
—
—
—
0
0
136
1170
1.23
1.23
3.3
3.3
25.46
37.93
ng/l
0.78
85
718
5
19
2.65
1.22
2.0
2.2
769.80
553.32
u/ml
—
5
19
281
2604
1.22
1.19
3.3
3.0
39.74
42.77
u/l
0.31
268
2471
94
779
1.26
1.18
1.7
1.7
1.03
1.09
mg/l
0.10
74
601
11
57
1.95
1.18
2.8
3.6
3.20
3.96
e9/l
1.12
11
57
42
311
1.39
1.15
6.7
8.8
-0.12
1.21
mmol/l
0.74
32
247
5
20
2.52
1.15
1.6
1.5
14.00
15.80
u/l
—
5
20
11
58
1.92
1.13
2.9
3.6
55.18
55.21
%
0.00
11
58
7
30
2.35
1.13
1.1
1.0
—
—
—
0
0
5
21
2.40
1.09
1.0
1.0
—
—
—
0
0
17
105
1.64
1.07
1.4
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
12
67
1.81
1.05
3.6
2.9
0.45
0.36
u/ml
—
7
37
49
379
1.33
1.04
5.9
5.7
—
—
—
0
0
47
363
1.33
1.01
7.9
6.7
104.34
104.52
mmol/l
0.10
47
363
5
23
2.19
0.98
1.0
1.3
—
—
—
0
0
5
23
2.19
0.98
10.0
7.8
—
57.00
—
0
8
13
77
1.71
0.96
1.0
1.3
—
—
—
0
0
31
417
0.72
0.95
1.4
1.6
—
—
—
0
0
18
117
1.56
0.95
1.8
2.0
—
—
—
0
0
91
771
1.23
0.95
3.7
3.5
1.01
1.02
kg/l
1.01
13
99
15
94
1.62
0.91
1.9
2.9
—
—
—
0
0
6
29
2.08
0.89
1.0
1.1
—
—
—
0
0
40
311
1.31
0.84
6.9
8.7
5.09
5.09
kpa
0.01
40
297
40
311
1.31
0.84
6.8
8.7
12.24
12.68
kpa
0.20
40
298
113
990
1.19
0.84
5.4
3.1
7.80
8.03
mmol/l
0.23
104
850
39
303
1.31
0.83
2.2
3.0
—
—
—
0
0
24
172
1.42
0.83
6.4
9.7
24.72
24.48
mmol/l
0.10
24
162
6
32
1.89
0.82
1.5
1.2
—
—
—
0
0
99
859
1.20
0.82
1.7
1.6
—
—
—
0
0
17
114
1.51
0.80
1.7
1.7
—
—
—
0
0
6
33
1.83
0.79
1.5
1.2
—
—
—
0
0
106
930
1.18
0.77
2.3
2.0
220.16
268.56
u/l
0.17
106
877
9
54
1.68
0.75
2.6
4.8
—
4097.50
—
0
6
106
935
1.18
0.73
1.6
1.6
1.39
1.42
mmol/l
0.09
96
814
36
284
1.29
0.70
2.3
1.8
—
—
—
0
0
120
1073
1.16
0.70
2.7
3.2
2.37
2.35
mmol/l
0.48
108
959
41
333
1.25
0.65
1.6
1.7
—
—
—
0
0
23
172
1.36
0.65
1.6
1.4
—
—
—
0
0
8
49
1.64
0.62
1.4
1.1
—
—
—
0
0
14
96
1.47
0.62
1.6
1.5
404.07
418.74
mg/l
0.07
14
91
101
900
1.16
0.62
4.7
3.8
5.07
9.41
mg/mmol
0.62
67
561
5
30
1.67
0.61
1.4
1.9
—
—
—
0
0
8
51
1.58
0.60
1.0
1.3
—
—
—
0
0
8
51
1.58
0.60
1.0
1.3
—
—
—
0
0
8
52
1.55
0.59
1.0
1.3
—
—
—
0
0
8
52
1.55
0.59
1.0
1.3
—
—
—
0
0
8
52
1.55
0.59
1.0
1.3
—
—
—
0
0
8
52
1.55
0.59
1.0
1.3
—
—
—
0
0
357
3461
1.16
0.59
12.4
10.5
84.68
87.60
ml/min/173m2
1.71
307
2808
41
338
1.23
0.58
1.6
1.8
—
—
—
0
0
136
1243
1.14
0.58
3.4
3.1
28.91
32.54
u/l
0.95
130
1194
24
185
1.31
0.57
2.6
2.2
19626.17
5569.38
u/l
0.49
11
77
6
36
1.68
0.57
4.0
3.9
—
—
—
0
0
6
36
1.68
0.57
1.7
1.5
—
—
—
0
0
38
312
1.24
0.56
2.3
2.3
27.67
30.61
u/l
0.59
33
266
6
37
1.63
0.55
1.0
1.3
—
—
—
0
0
373
3633
1.17
0.55
4.5
4.0
4.77
4.75
mmol/l
0.16
353
3414
9
60
1.51
0.54
1.2
1.3
—
—
—
0
0
6
38
1.59
0.54
2.8
3.3
2.33
3.00
nmol/l
—
6
38
148
1369
1.12
0.52
3.7
3.2
—
—
—
0
0
6
40
1.51
0.52
1.0
3.5
18.50
56.93
u/ml
—
6
40
65
570
1.16
0.50
3.7
3.3
262.00
370.04
ng/l
0.24
51
399
32
263
1.23
0.48
7.6
3.7
1.10
1.99
mmol/l
0.69
25
202
17
130
1.32
0.44
1.5
1.3
—
—
—
0
0
30
250
1.21
0.41
2.4
2.5
64.36
74.11
ml/min/173m2
0.94
11
104
370
3621
1.13
0.41
4.5
3.9
1.51
1.47
mmol/l
0.80
348
3391
0
17
0.00
0.40
0.0
1.1
—
103.40
—
0
17
5
35
1.43
0.39
1.0
1.0
—
—
—
0
0
21
169
1.25
0.39
1.6
2.6
0.13
0.11
e6/l
0.13
21
163
45
513
0.86
0.38
2.7
2.6
0.67
0.70
ug/l
0.18
31
306
20
161
1.25
0.37
1.1
1.4
250.87
252.28
miu/ml
—
8
74
14
107
1.32
0.37
1.2
1.1
—
—
—
0
0
29
244
1.20
0.37
1.2
1.3
—
47.41
—
0
16
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
6
45
1.34
0.34
1.8
1.4
—
—
—
0
0
80
869
0.90
0.33
4.0
4.1
1.84
2.29
ug/l
0.46
75
788
374
3677
1.11
0.31
4.9
4.4
2.83
2.84
mmol/l
0.16
352
3441
7
54
1.30
0.30
1.7
1.4
—
—
—
0
0
76
701
1.10
0.29
1.8
1.4
—
—
—
0
0
40
356
1.14
0.28
2.4
1.9
—
—
—
0
0
11
85
1.30
0.28
1.4
1.5
330.18
183.18
e6/l
0.26
11
68
11
85
1.30
0.28
1.5
1.5
—
—
—
0
0
11
85
1.30
0.28
1.4
1.4
5.73
5.91
e6/l
0.01
11
66
8
65
1.23
0.27
1.3
1.3
3.10
2.78
ug/l
—
8
58
8
66
1.22
0.27
1.3
1.4
—
—
—
0
0
26
225
1.17
0.26
1.3
1.3
—
—
—
0
0
11
86
1.29
0.26
1.1
1.2
—
—
—
0
0
64
693
0.91
0.26
4.0
3.7
22.29
20.88
%
0.25
28
291
13
159
0.81
0.25
1.6
1.5
—
—
—
0
0
99
935
1.08
0.23
4.3
3.5
0.00
0.01
estimate
0.50
33
330
5
39
1.29
0.23
1.2
2.0
—
—
—
0
0
23
200
1.16
0.23
5.8
3.4
2.24
1.55
mmol/l
0.32
17
143
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
28.10
—
0
10
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
13
109
1.20
0.18
1.2
1.1
—
—
—
0
0
7
60
1.17
0.18
1.3
1.1
—
—
—
0
0
7
62
1.13
0.17
1.7
1.4
—
—
—
0
0
354
3500
1.06
0.15
4.1
3.6
1.25
1.29
mmol/l
0.47
330
3264
20
182
1.10
0.11
1.5
1.5
—
—
—
0
0
13
146
0.89
0.10
1.5
1.4
—
—
—
0
0
13
146
0.89
0.10
1.5
1.4
—
—
—
0
0
13
146
0.89
0.10
1.5
1.4
—
—
—
0
0
13
146
0.89
0.10
1.5
1.4
—
—
—
0
0
5
44
1.14
0.10
1.2
1.9
—
—
—
0
0
10
87
1.15
0.09
1.2
1.7
—
—
—
0
0
24
223
1.08
0.09
1.3
1.4
29.29
26.88
iu/l
0.13
18
191
10
113
0.88
0.08
1.2
1.1
—
—
—
0
0
7
64
1.10
0.08
1.6
1.3
—
—
—
0
0
7
64
1.10
0.08
1.6
1.3
—
—
—
0
0
7
81
0.86
0.07
1.6
1.5
—
—
—
0
0
9
88
1.02
0.07
1.1
1.1
—
—
—
0
0
24
253
0.95
0.05
1.5
1.5
—
—
—
0
0
11
120
0.91
0.05
1.5
1.6
—
—
—
0
0
11
102
1.08
0.03
1.6
1.7
—
—
—
0
0
17
162
1.05
0.02
1.4
1.9
—
—
—
0
0
12
113
1.06
0.02
7.2
9.0
1.69
1.58
%
0.23
12
105
18
174
1.04
0.00
1.5
1.5
221.00
268.50
mu/l
0.62
18
157
15
147
1.02
0.00
2.1
1.7
—
—
—
0
0
17
167
1.02
0.00
1.8
1.7
3.01
3.35
mg/l
0.13
17
121
55
555
0.99
0.00
2.3
2.8
2.45
2.44
mmol/l
0.20
47
487
6
61
0.98
0.00
2.0
1.6
—
—
—
0
0
6
62
0.97
0.00
1.2
1.7
—
—
—
0
0
6
62
0.97
0.00
1.2
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
83
0.96
-0.00
1.8
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
1.27
—
0
9
6
63
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
49
1.02
-0.00
2.0
1.4
—
—
—
0
0
6
69
0.87
-0.00
1.5
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
11
110
1.00
-0.00
1.4
1.3
—
—
—
0
0
8
86
0.93
-0.00
1.8
1.6
—
—
—
0
0
6
64
0.94
-0.00
1.5
1.4
6.83
7.06
mmol/l
—
6
52
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_VITILIGO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_VITILIGO | 1.203 [0.93, 1.55] | 0.156 |
| Birth year | 0.994 [0.99, 1.0] | 0.165 |
During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 1518 females with L12_VITILIGO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_VITILIGO | 1.183 [0.94, 1.49] | 0.157 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 1189 males with L12_VITILIGO died.
Mortality risk
Mortality risk for people of age
years, who have L12_VITILIGO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.11% | 0.247% |
| 5 | 0.704% | 1.539% |
| 10 | 1.552% | 3.646% |
| 15 | 3.01% | 6.626% |
| 20 | 5.436% | 10.822% |
Relationships between endpoints
↥Index endpoint: L12_VITILIGO – Vitiligo
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data