Vitiligo: Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
412 |
4. Check minimum number of eventsNone |
412 |
5. Include endpointsNone |
412 |
6. Filter based on genotype QC (FinnGen only) |
412 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L80-L99
- Name in latin
- Vitiligo
Similar endpoints
↥List of similar endpoints to
Vitiligo
based on the number of shared cases.
Similar with more cases:
- Other disorders of skin and subcutaneous tissue
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3372 | 1868 | 1488 |
| Only index persons | 3076 | 1720 | 1356 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | 0.04 |
| Only index persons | 0.06 | 0.06 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 36.14 | 37.31 | 34.62 |
| Only index persons | 36.81 | 38.02 | 35.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 412 | 251 | 161 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.07 |
| Median age at first event (years) | 43.92 | 42.52 | 46.10 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 359
- Matched controls
- 3588
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L80
ICD-10 Finland
Vitiligo
4503599627370496.0
323.0
346
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.4
21.4
59
107
E0000UV
ATC
NA
2.9
19.9
178
908
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.6
19.0
101
356
D07AD01
ATC
clobetasol; topical
3.8
17.4
82
261
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
19.1
16.7
25
14
D07AC01
ATC
betamethasone; topical
2.6
15.3
148
759
70905
ICD-8 Finland
Other diseases of skin, Vitiligo
+∞
14.7
14
*
D05AX02
ATC
calcipotriol; topical
6.2
12.0
32
56
H03AA01
ATC
levothyroxine sodium; systemic
2.5
10.8
100
486
D07AC13
ATC
mometasone; topical
2.2
8.9
109
597
107
Kela drug reimbursment
Pernicious anaemia
11.1
8.4
15
14
TQW80
NOMESCO Finland
Local dermatologic skincare
7.2
7.9
18
26
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
6.6
7.8
19
30
104
Kela drug reimbursment
Thyroid insufficiency
3.4
7.7
36
113
L63.8
ICD-10 Finland
Other alopecia areata
81.7
7.4
8
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
8.6
7.4
15
18
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
20.5
7.2
10
5
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.8
7.1
45
175
L40.0
ICD-10 Finland
Psoriasis vulgaris
4.6
6.8
22
50
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
6.6
105
627
H02AB07
ATC
prednisone; oral
2.4
6.6
57
262
D07AB08
ATC
desonide; topical
2.6
6.6
46
189
E000001
ATC
NA
2.1
6.6
83
453
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.8
6.4
40
153
L94.0
ICD-10 Finland
Localized scleroderma [morphea]
+∞
6.3
6
*
D05BA02
ATC
methoxsalen; oral
+∞
6.3
6
*
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
12.8
6.1
10
8
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
64
258
2.75
11.24
1.3
1.2
220.4
156.4
iu/ml
0.50
26
114
36
119
3.22
8.94
4.1
1.9
—
—
—
0
0
19
40
4.93
8.67
2.5
3.7
58.3
52.2
u/ml
—
7
12
132
801
1.95
8.61
1.4
1.3
0.7
2.0
u/ml
1.39
26
210
12
16
7.70
8.45
1.0
1.2
—
—
—
0
0
316
2584
1.96
7.63
5.5
3.7
14.9
14.5
pmol/l
1.71
292
2373
196
1440
1.69
6.31
8.0
6.5
1.2
1.2
mmol/l
0.38
165
1232
24
77
3.25
6.27
1.0
1.2
—
1.0
—
0
5
356
3118
2.04
5.90
6.3
4.3
1.9
1.8
mu/l
0.40
342
2885
165
1175
1.67
5.87
1.9
1.8
94.6
96.0
pmol/l
0.11
84
603
11
20
5.62
5.83
2.1
2.0
15.0
11.3
%
—
6
13
176
1299
1.62
5.30
2.7
2.2
75.1
75.7
nmol/l
0.09
164
1186
108
705
1.72
5.22
2.4
2.1
3.1
2.9
mg/l
0.31
94
613
23
82
2.91
5.07
1.0
1.2
—
—
—
0
0
174
1320
1.55
4.46
7.0
5.6
1.2
1.2
mmol/l
0.30
159
1211
291
2489
1.58
4.21
8.4
7.0
76.9
76.3
u/l
0.09
284
2342
11
28
4.01
4.00
1.0
1.1
—
94.4
—
0
5
12
33
3.72
3.95
1.0
1.2
—
—
—
0
0
12
33
3.72
3.95
1.2
1.1
—
—
—
0
0
12
33
3.72
3.95
1.2
1.1
—
—
—
0
0
285
2445
1.54
3.90
5.1
3.8
10.3
10.2
mm/h
0.06
269
2265
12
34
3.61
3.79
1.2
1.1
—
—
—
0
0
12
34
3.61
3.79
1.2
1.1
—
—
—
0
0
12
34
3.61
3.79
1.2
1.1
—
—
—
0
0
231
1913
1.47
3.64
10.9
9.3
3.8
4.0
e9/l
0.88
212
1668
74
480
1.66
3.58
1.5
1.6
1013.2
1167.5
nmol/l
0.84
54
366
7
9
7.89
3.57
1.1
1.1
87.1
92.8
%
—
7
9
7
9
7.89
3.57
1.1
1.1
—
—
—
0
0
60
379
1.68
3.21
2.8
2.0
21.9
24.3
%
0.87
53
338
9
20
4.58
3.13
2.1
1.9
—
—
—
0
0
9
22
4.16
2.89
1.6
1.3
—
—
—
0
0
126
965
1.44
2.83
2.3
2.4
57.8
55.7
u/l
0.35
116
901
12
42
2.91
2.77
1.3
1.4
—
—
—
0
0
334
3046
1.51
2.73
5.6
4.9
39.4
38.8
mmol/mol
0.45
309
2864
195
1624
1.38
2.67
5.2
6.0
11.2
11.0
umol/l
0.07
190
1545
137
1080
1.40
2.59
3.6
2.9
—
—
—
0
0
79
567
1.49
2.46
1.7
1.7
428.0
449.3
pmol/l
0.30
67
498
364
3403
1.60
2.43
14.9
11.8
18.1
21.7
mg/l
1.73
300
2624
181
1510
1.35
2.37
3.3
2.6
104.8
114.3
ug/l
0.28
168
1411
109
842
1.40
2.29
3.6
2.7
0.2
0.4
e6/l
1.06
81
620
88
656
1.43
2.25
1.5
1.4
20.5
21.2
nmol/l
0.19
76
563
209
1795
1.33
2.21
5.0
4.5
6.9
6.5
mmol/l
1.43
191
1655
60
419
1.51
2.13
2.2
1.9
30.2
29.7
s
0.25
60
408
52
353
1.54
2.11
2.5
2.3
6.9
7.8
umol/l
0.16
47
295
16
76
2.15
2.05
1.2
1.1
—
—
—
0
0
9
32
2.85
2.01
1.3
1.1
—
—
—
0
0
17
84
2.07
1.98
1.4
1.4
241.8
332.2
ug/g
0.99
12
43
11
45
2.48
1.94
2.6
1.8
12.8
13.2
%
0.66
11
45
78
587
1.41
1.89
1.8
2.2
—
—
—
0
0
27
160
1.74
1.87
1.3
1.7
—
—
—
0
0
43
288
1.55
1.86
2.9
4.4
3.3
22.3
ug/l
0.69
35
236
187
1608
1.30
1.86
4.8
4.4
0.0
0.0
estimate
0.00
32
315
23
130
1.81
1.85
1.6
1.5
—
—
—
0
0
19
101
1.92
1.84
2.5
2.2
99.8
91.9
%
0.79
19
93
382
3653
1.63
1.82
11.7
9.2
25.4
27.4
u/l
1.86
377
3541
70
521
1.41
1.81
1.7
2.1
—
—
—
0
0
78
592
1.39
1.80
1.3
1.3
25.9
9.3
u/ml
0.54
28
229
344
3225
1.40
1.79
4.2
4.0
5.9
5.8
mmol/l
0.59
322
2990
278
2526
1.31
1.79
3.6
3.4
—
—
—
0
0
100
792
1.35
1.78
2.3
2.4
351.0
5750.1
umol/l
2.84
91
703
188
1625
1.29
1.78
3.7
3.2
0.0
0.0
estimate
0.00
31
301
12
54
2.26
1.75
1.7
1.3
4.2
4.1
u/ml
—
6
25
185
1598
1.29
1.75
3.6
3.2
0.0
0.0
estimate
0.00
30
312
32
204
1.62
1.71
7.0
3.1
118.4
71.8
ng/l
1.39
27
184
52
370
1.46
1.71
4.5
4.0
31.6
31.6
%
0.00
38
254
64
474
1.41
1.70
2.2
3.2
0.8
0.8
mmol/l
0.10
58
451
12
55
2.22
1.69
1.6
1.3
1.4
2.8
u/ml
—
5
18
10
42
2.42
1.69
1.4
1.2
—
—
—
0
0
92
727
1.34
1.66
2.3
2.8
663.6
858.8
ng/l
0.61
76
600
129
1070
1.30
1.65
3.3
3.3
26.2
36.8
ng/l
0.62
81
653
91
722
1.33
1.59
1.8
1.7
1.1
1.1
mg/l
0.11
72
556
6
20
3.03
1.58
8.7
2.5
—
—
—
0
0
5
15
3.36
1.52
1.2
2.0
—
—
—
0
0
5
15
3.36
1.52
1.2
1.1
66.4
116.0
u/l
—
5
10
5
15
3.36
1.52
1.2
1.1
10.4
48.7
u/l
—
5
10
5
15
3.36
1.52
1.2
2.0
—
—
—
0
0
7
27
2.62
1.52
1.1
1.0
—
—
—
0
0
37
253
1.51
1.49
6.8
9.7
123.7
122.5
g/l
0.13
37
243
19
110
1.76
1.45
1.7
1.5
—
—
—
0
0
5
16
3.15
1.44
1.0
1.1
—
—
—
0
0
5
16
3.15
1.44
1.0
1.1
—
—
—
0
0
16
88
1.85
1.43
2.0
1.9
1.9
5.3
iu/l
—
6
31
47
342
1.42
1.40
6.1
5.8
—
—
—
0
0
31
207
1.54
1.40
1.6
1.4
—
—
—
0
0
77
609
1.33
1.38
1.3
1.3
25.6
28.2
iu/ml
0.10
26
199
5
17
2.96
1.36
1.0
1.1
—
—
—
0
0
5
17
2.96
1.36
1.0
1.1
—
—
—
0
0
5
17
2.96
1.36
1.0
1.0
—
—
—
0
0
21
128
1.68
1.36
1.3
1.4
—
—
—
0
0
63
485
1.35
1.35
2.9
2.5
0.7
0.9
e6/l
0.33
34
259
13
68
1.94
1.35
1.1
1.3
—
—
—
0
0
5
18
2.80
1.29
2.0
2.3
769.8
534.9
u/ml
—
5
18
60
464
1.34
1.26
3.0
2.6
1.9
2.9
e6/l
0.82
31
239
41
298
1.42
1.24
6.8
8.8
-0.1
1.3
mmol/l
0.77
30
237
11
56
1.99
1.23
2.8
3.3
3.2
3.9
e9/l
1.06
11
56
58
449
1.34
1.21
1.7
1.9
—
—
—
0
0
11
57
1.96
1.18
2.9
3.4
55.2
55.4
%
0.02
11
57
90
745
1.27
1.15
2.1
2.2
—
—
—
0
0
29
201
1.48
1.13
1.1
1.0
—
—
—
0
0
169
1502
1.21
1.12
3.7
3.9
—
—
—
0
0
5
21
2.40
1.09
10.0
8.4
—
57.0
—
0
8
9
46
1.98
1.04
1.1
1.1
—
—
—
0
0
343
3281
1.27
1.04
15.7
12.5
40.1
40.6
%
0.61
260
2613
38
284
1.37
1.01
2.2
3.0
—
—
—
0
0
9
49
1.86
0.99
2.6
3.3
—
4887.0
—
0
5
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
11
62
1.80
0.95
3.8
2.8
0.4
0.4
u/ml
—
6
34
44
341
1.33
0.94
8.4
6.7
104.5
104.3
mmol/l
0.12
44
331
14
86
1.65
0.92
1.6
1.5
404.1
416.1
mg/l
0.06
14
81
39
298
1.34
0.92
7.1
8.8
5.1
5.1
kpa
0.09
39
285
39
298
1.34
0.92
7.0
8.7
12.3
12.6
kpa
0.15
39
286
11
63
1.77
0.91
1.1
1.9
—
—
—
0
0
6
29
2.08
0.89
1.0
1.1
—
—
—
0
0
22
153
1.46
0.87
1.6
1.4
—
—
—
0
0
91
781
1.21
0.85
1.6
1.6
—
—
—
0
0
259
2432
1.17
0.84
3.3
2.9
40.0
43.4
u/l
0.32
248
2306
29
384
0.74
0.83
1.4
1.6
—
—
—
0
0
100
869
1.20
0.82
1.7
1.6
1.4
1.4
mmol/l
0.07
90
756
14
90
1.58
0.79
1.9
2.9
—
—
—
0
0
83
712
1.21
0.78
3.7
3.5
1.0
1.0
kg/l
1.04
13
92
6
34
1.78
0.76
1.7
1.6
—
—
—
0
0
97
848
1.19
0.75
2.4
2.0
232.1
278.1
u/l
0.15
97
796
130
1167
1.17
0.73
3.4
3.1
28.9
32.9
u/l
1.05
124
1119
5
25
2.01
0.73
1.4
1.2
—
—
—
0
0
16
109
1.49
0.72
1.9
2.0
—
—
—
0
0
5
26
1.93
0.71
1.4
1.2
—
—
—
0
0
15
105
1.44
0.61
1.7
1.8
—
—
—
0
0
62
532
1.19
0.60
3.8
3.2
253.8
244.6
ng/l
0.02
48
372
111
1000
1.15
0.60
2.6
3.2
2.4
2.4
mmol/l
0.28
98
889
39
319
1.25
0.60
1.6
1.8
—
—
—
0
0
14
97
1.46
0.59
1.4
1.7
4.3
3.6
g/l
—
9
73
14
97
1.46
0.59
1.4
1.7
—
—
—
0
0
6
35
1.72
0.58
2.8
3.3
2.3
3.2
nmol/l
—
6
35
11
73
1.52
0.56
1.0
1.3
—
—
—
0
0
17
124
1.39
0.56
1.5
1.3
—
—
—
0
0
6
38
1.59
0.54
1.5
1.8
7.8
7.7
mmol/l
—
6
23
38
314
1.23
0.54
1.6
1.7
—
—
—
0
0
11
74
1.50
0.54
1.5
1.5
—
—
—
0
0
36
296
1.24
0.54
2.3
2.3
27.0
30.8
u/l
0.81
31
251
6
39
1.55
0.53
1.8
1.5
—
—
—
0
0
6
39
1.55
0.53
1.7
2.6
2.7
7.2
u/ml
—
6
34
28
224
1.27
0.52
2.5
2.6
64.4
71.9
ml/min/173m2
0.67
11
96
14
100
1.41
0.52
1.2
1.1
—
—
—
0
0
32
261
1.25
0.51
2.2
1.9
—
—
—
0
0
330
3207
1.15
0.49
12.6
10.7
84.3
87.5
ml/min/173m2
1.74
281
2595
11
76
1.46
0.48
1.4
1.5
5.7
6.5
e6/l
0.06
11
60
11
76
1.46
0.48
1.4
1.6
330.2
207.4
e6/l
0.21
11
61
7
48
1.47
0.47
1.7
1.4
—
—
—
0
0
346
3377
1.15
0.47
4.6
4.0
4.8
4.7
mmol/l
0.22
325
3175
11
77
1.44
0.46
1.1
1.1
—
—
—
0
0
11
77
1.44
0.46
3.2
4.3
3.7
3.9
mmol/l
0.73
11
71
28
229
1.24
0.45
1.2
1.3
—
36.1
—
0
12
21
166
1.28
0.44
2.8
2.1
23987.2
6112.5
u/l
—
9
68
9
128
0.70
0.44
2.6
1.8
—
—
—
0
0
8
57
1.41
0.42
3.4
3.8
15.4
31.4
u/ml
—
8
57
135
1260
1.11
0.41
3.8
3.2
—
—
—
0
0
5
35
1.43
0.39
1.0
3.9
20.8
63.5
u/ml
—
5
35
5
36
1.39
0.38
4.4
3.8
—
—
—
0
0
5
36
1.39
0.38
1.0
1.3
—
—
—
0
0
5
36
1.39
0.38
1.0
1.0
—
—
—
0
0
5
37
1.36
0.37
1.2
2.0
—
—
—
0
0
6
41
1.47
0.36
1.0
1.1
—
—
—
0
0
6
42
1.43
0.35
1.5
1.1
—
—
—
0
0
28
237
1.19
0.34
8.3
3.7
1.0
2.1
mmol/l
0.85
22
177
92
851
1.10
0.33
4.4
3.4
0.0
0.0
estimate
0.50
31
309
10
74
1.36
0.32
1.5
3.6
—
2.6
—
0
12
343
3366
1.11
0.32
4.5
3.9
1.5
1.5
mmol/l
0.53
320
3150
6
47
1.28
0.32
1.2
1.1
—
—
—
0
0
20
166
1.22
0.30
1.5
1.4
—
—
—
0
0
13
102
1.28
0.30
1.2
1.1
—
—
—
0
0
7
55
1.28
0.30
1.7
1.4
—
—
—
0
0
7
55
1.28
0.30
1.3
1.2
3.1
2.8
ug/l
—
7
50
70
643
1.11
0.30
1.7
1.4
—
—
—
0
0
7
56
1.25
0.29
1.3
1.1
—
—
—
0
0
7
57
1.23
0.29
1.1
1.3
—
—
—
0
0
44
490
0.89
0.29
2.7
2.6
0.7
0.7
ug/l
0.18
30
291
77
829
0.91
0.28
4.1
4.2
1.9
2.3
ug/l
0.40
72
753
8
64
1.25
0.27
1.3
1.4
—
—
—
0
0
347
3419
1.09
0.25
5.0
4.3
2.8
2.8
mmol/l
0.10
324
3196
5
41
1.22
0.22
1.2
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
2.0
1.5
—
—
—
0
0
10
80
1.26
0.20
1.2
1.7
—
—
—
0
0
6
48
1.25
0.20
1.2
1.1
—
—
—
0
0
6
51
1.18
0.19
1.0
1.3
—
—
—
0
0
6
51
1.18
0.19
1.0
1.3
—
—
—
0
0
11
90
1.23
0.19
1.6
1.7
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
—
—
—
0
0
62
659
0.93
0.18
4.0
3.8
22.2
21.0
%
0.20
27
274
36
330
1.10
0.17
2.3
2.0
—
—
—
0
0
7
63
1.11
0.17
1.6
1.3
—
—
—
0
0
7
63
1.11
0.17
1.6
1.3
—
—
—
0
0
23
206
1.12
0.16
1.3
1.2
—
—
—
0
0
17
149
1.15
0.16
1.1
1.4
146.1
261.0
miu/ml
—
7
69
18
159
1.14
0.15
1.6
2.4
0.1
0.1
e6/l
0.17
18
154
17
151
1.13
0.13
1.4
1.8
—
—
—
0
0
15
135
1.12
0.10
12.8
4.3
23.2
24.2
mmol/l
0.96
15
126
6
56
1.07
0.08
1.0
1.1
—
—
—
0
0
13
144
0.90
0.08
1.6
1.5
—
—
—
0
0
6
58
1.03
0.08
2.0
1.7
—
—
—
0
0
22
205
1.08
0.08
1.3
1.4
30.6
26.0
iu/l
0.25
17
175
8
77
1.04
0.07
1.7
1.6
—
—
—
0
0
24
226
1.07
0.06
1.5
1.5
—
—
—
0
0
9
102
0.88
0.06
1.2
1.1
—
—
—
0
0
327
3254
1.02
0.04
4.1
3.6
1.3
1.3
mmol/l
0.20
303
3038
50
514
0.97
0.04
2.0
2.8
2.4
2.4
mmol/l
0.13
42
448
10
99
1.01
0.00
1.4
1.3
—
—
—
0
0
13
131
0.99
0.00
1.5
1.4
—
—
—
0
0
13
131
0.99
0.00
1.5
1.4
—
—
—
0
0
13
131
0.99
0.00
1.5
1.4
—
—
—
0
0
13
131
0.99
0.00
1.5
1.4
—
—
—
0
0
11
105
1.05
0.00
1.5
1.5
—
—
—
0
0
15
155
0.97
0.00
1.3
1.4
195.1
276.6
mu/l
1.86
15
139
6
59
1.02
0.00
1.5
1.4
6.8
6.9
mmol/l
—
6
38
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
7
74
0.95
0.00
1.6
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
8
80
1.00
0.00
1.7
1.6
—
—
—
0
0
6
66
0.91
0.00
1.5
1.8
—
—
—
0
0
11
110
1.00
0.00
7.7
9.3
1.8
1.6
%
0.43
11
102
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
1.3
—
0
8
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
25.9
—
0
8
8
80
1.00
0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_VITILIGO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_VITILIGO | 1.203 [0.93, 1.55] | 0.156 |
| Birth year | 0.994 [0.99, 1.0] | 0.165 |
During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 1518 females with L12_VITILIGO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_VITILIGO | 1.183 [0.94, 1.49] | 0.157 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 1189 males with L12_VITILIGO died.
Mortality risk
Mortality risk for people of age
years, who have L12_VITILIGO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.11% | 0.247% |
| 5 | 0.704% | 1.539% |
| 10 | 1.552% | 3.646% |
| 15 | 3.01% | 6.626% |
| 20 | 5.436% | 10.822% |
Relationships between endpoints
↥Index endpoint: L12_VITILIGO – Vitiligo
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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