Meckel's diverticulum

Q17_MECKELS_DIVERTICULUM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q43.0
  • Hospital discharge: ICD-9 7510A|7510B
  • Cause of death: ICD-10 Q43.0
  • Cause of death: ICD-9 7510A|7510B

2 out of 7 registries used, show all original rules.

228

4. Check minimum number of events

None

228

5. Include endpoints

None

228

6. Filter based on genotype QC (FinnGen only)

220

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 220 101 119
Unadjusted period prevalence (%) 0.05 0.04 0.05
Median age at first event (years) 42.54 43.17 42.00

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
228
Matched controls
2280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q43.0
ICD-10 Finland
Meckel diverticulum
+∞
205.6
165
*
7510A
ICD-9 Finland
Other congenital anomalies of digestive system, Meckel's diverticulum[DIVERTICULUM MECKELI]
+∞
65.9
60
*
JFA73
NOMESCO Finland
Excision of lesion of small intestine
+∞
42.0
39
*
JEA00
NOMESCO Finland
Appendectomy
9.3
39.1
54
74
6421
FHL
Appendicectomy
11.4
38.4
44
47
JFB00
NOMESCO Finland
Partial resection of small intestine
60.1
38.2
44
9
6401
FHL
Enterotomy and any possible small procedure related to it, eg removal of a foreign object, diverticulum or polyps
+∞
33.1
31
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.6
20.0
121
550
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.6
20.0
27
35
JAH01
NOMESCO Finland
Laparoscopy
8.4
19.5
27
36
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.8
18.7
48
119
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
15.1
13.6
22
16
JN3AD
NOMESCO Finland
Abdominal CT examination
3.7
11.3
41
129
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
9.6
11.1
22
25
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.8
10.6
20
37
6402
FHL
Small bowel resection
+∞
10.5
10
*
UJF32
NOMESCO Finland
Coloscopy
2.7
10.1
73
342
ZXD05
NOMESCO Finland
Urgent procedure
2.5
9.7
90
473
P01AB01
ATC
metronidazole; oral, rectal
2.4
9.2
107
621
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
3.6
8.9
31
95
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
8.8
75
377
JFA74
NOMESCO Finland
Laparoscopic excision of lesion of small intestine
+∞
8.4
8
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
7.8
59
279
JAH00
NOMESCO Finland
Laparotomy
7.6
7.6
17
24
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.6
7.3
46
199
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
7.0
71
380
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
7.0
111
709
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
23.3
6.7
9
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
6.5
90
543
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
9.0
6.1
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
113
759
1.97
5.90
5.4
4.6
35.19
36.32
g/l
1.25
106
725
77
457
2.03
5.68
4.2
4.3
—
—
—
0
0
135
973
1.95
5.64
6.3
6.1
10.18
11.27
umol/l
0.98
127
933
77
472
1.95
5.10
3.4
3.8
—
—
—
0
0
100
673
1.87
4.96
2.1
1.9
95.20
95.63
pmol/l
0.03
58
359
68
403
1.98
4.94
2.7
2.2
2.67
2.97
mg/l
0.68
63
356
81
511
1.91
4.89
3.6
2.8
0.33
0.34
e6/l
0.03
63
387
144
1090
1.87
4.87
9.7
9.5
4.78
4.10
e9/l
1.83
124
959
119
850
1.84
4.84
6.8
7.2
1.21
1.21
mmol/l
0.39
98
732
79
496
1.91
4.83
3.6
2.7
—
—
—
0
0
176
1429
2.02
4.73
8.7
7.2
77.53
76.37
u/l
0.18
166
1349
43
218
2.20
4.71
1.3
1.3
—
—
—
0
0
63
374
1.95
4.52
3.5
2.3
5.28
4.40
e6/l
0.30
58
338
58
342
1.93
4.22
4.7
3.5
122.46
166.46
ng/l
0.16
41
253
84
560
1.79
4.14
4.4
2.9
73.47
160.55
e6/l
0.30
66
435
155
1236
1.79
4.05
4.3
3.8
—
—
—
0
0
40
213
2.06
3.85
1.4
1.3
—
—
—
0
0
106
772
1.70
3.73
6.6
6.2
1.21
1.21
mmol/l
0.03
92
715
110
812
1.69
3.67
9.0
9.1
0.00
0.00
e9/l
0.84
89
662
44
247
1.97
3.66
3.4
2.6
248.83
128.74
ug/g
0.32
39
201
91
645
1.68
3.49
4.8
3.6
15.97
90.84
e6/l
1.12
69
462
210
1886
2.44
3.42
19.0
13.0
27.42
22.26
mg/l
1.25
181
1467
135
1066
1.65
3.37
5.6
4.7
6.58
6.65
mmol/l
0.19
129
995
96
699
1.64
3.28
2.4
1.9
—
—
—
0
0
210
1893
2.39
3.26
20.7
14.8
3.97
3.96
mmol/l
0.03
203
1849
10
24
4.31
3.23
1.4
1.5
—
—
—
0
0
209
1888
2.28
3.10
20.5
14.7
139.52
139.70
mmol/l
0.41
202
1846
115
886
1.60
3.07
6.3
6.0
—
—
—
0
0
79
556
1.64
3.04
3.1
2.3
—
—
—
0
0
119
927
1.59
3.01
6.2
5.6
0.04
0.04
e9/l
0.03
105
814
119
928
1.59
2.99
6.2
5.6
0.60
0.57
e9/l
0.66
105
816
56
361
1.73
2.99
2.4
2.9
559.60
571.29
mosm/kgh2o
0.15
48
310
96
713
1.60
2.96
3.1
3.2
6.69
5.78
ph
—
8
67
121
954
1.57
2.86
6.3
5.7
1.90
1.93
e9/l
0.09
106
855
47
292
1.77
2.84
3.3
2.8
1.37
1.65
e6/l
0.20
23
164
160
1348
1.63
2.83
3.8
3.1
37.88
46.01
u/l
1.86
147
1286
58
383
1.69
2.83
1.8
1.8
0.92
1.15
mg/l
0.37
48
301
112
870
1.56
2.81
6.5
5.6
2.59
2.82
%
0.61
103
823
30
162
1.98
2.78
4.0
3.9
1.45
1.67
mmol/l
0.13
24
128
112
872
1.56
2.77
6.7
6.0
8.29
8.48
%
0.29
105
829
46
287
1.76
2.74
4.4
3.8
0.81
0.83
mmol/l
0.61
41
272
102
781
1.55
2.69
11.9
11.7
1.32
1.22
inr
0.31
29
228
17
74
2.40
2.65
1.0
1.1
—
—
—
0
0
121
965
1.54
2.64
6.9
6.1
0.19
0.19
e9/l
0.01
107
861
114
898
1.54
2.63
6.5
5.7
27.13
28.05
%
0.39
107
857
108
844
1.53
2.57
6.7
5.7
0.59
0.67
%
0.96
100
794
112
884
1.52
2.53
6.9
5.5
59.37
56.95
%
1.35
105
841
30
168
1.90
2.52
4.1
3.9
—
—
—
0
0
66
465
1.59
2.47
2.9
2.8
—
—
—
0
0
72
523
1.55
2.35
3.8
3.7
7.41
7.40
ph
0.45
11
91
158
1356
1.54
2.32
4.1
3.8
14.59
14.63
pmol/l
0.08
147
1240
109
876
1.47
2.15
4.5
4.7
0.00
0.00
estimate
-0.00
21
162
109
877
1.47
2.14
3.3
3.4
0.00
0.01
estimate
0.50
21
171
27
155
1.84
2.11
10.0
7.5
—
—
—
0
0
10
37
2.78
2.10
1.4
2.2
—
—
—
0
0
32
195
1.75
2.07
7.3
9.6
-0.14
1.15
mmol/l
0.67
23
156
156
1353
1.48
2.03
4.2
3.8
11.42
10.55
mm/h
0.29
141
1260
38
252
1.61
1.81
1.7
2.1
—
—
—
0
0
63
470
1.47
1.77
7.5
6.9
—
—
—
0
0
33
214
1.63
1.72
1.4
1.2
—
—
—
0
0
17
90
1.96
1.70
10.6
13.7
—
—
—
0
0
107
886
1.39
1.67
3.4
3.4
0.00
0.00
estimate
-0.00
20
151
8
32
2.55
1.61
1.5
3.2
—
—
—
0
0
184
1685
1.48
1.52
4.9
4.4
1.66
1.86
mu/l
2.66
172
1551
43
306
1.50
1.51
3.1
3.1
2.43
2.44
mmol/l
0.24
38
275
47
341
1.48
1.51
1.8
1.8
367.44
455.25
pmol/l
2.13
39
293
11
52
2.17
1.47
3.7
1.7
281.40
659.40
u/l
—
5
11
94
781
1.35
1.38
3.6
2.7
132.96
124.37
ug/l
0.09
83
729
6
23
2.65
1.37
18.7
16.1
1114.50
1380.91
nmol/l
—
6
23
13
68
1.97
1.36
1.6
1.3
9.94
7.20
u/l
0.40
13
55
144
1278
1.34
1.34
3.6
3.6
—
—
—
0
0
52
395
1.41
1.31
3.0
3.3
—
—
—
0
0
31
213
1.53
1.29
7.7
6.7
105.35
103.97
mmol/l
0.84
31
213
8
35
2.33
1.28
1.5
1.3
68.13
66.09
%
—
8
35
29
197
1.54
1.27
1.6
1.5
—
—
—
0
0
219
2113
1.92
1.24
27.4
19.1
6.96
6.63
e9/l
1.68
212
2065
219
2113
1.92
1.24
27.2
19.0
30.04
30.32
pg
1.65
214
2090
219
2113
1.92
1.24
27.5
19.2
135.88
138.15
g/l
1.41
214
2087
219
2113
1.92
1.24
27.4
19.1
4.57
4.58
e12/l
0.05
211
2065
219
2112
1.94
1.24
27.3
19.0
90.09
90.70
fl
1.29
214
2089
219
2111
1.95
1.24
27.7
19.1
40.21
40.97
%
0.97
205
1991
219
2110
1.96
1.24
27.6
19.1
258.12
247.56
e9/l
1.78
212
2065
6
26
2.34
1.19
6.5
3.6
2.33
3.66
nmol/l
—
6
26
52
402
1.38
1.19
1.4
1.4
2.28
2.38
g/l
0.16
28
258
10
50
2.05
1.18
1.2
1.4
381.00
286.24
ug/g
—
5
26
7
30
2.37
1.13
2.0
3.2
67.86
59.97
%
—
7
30
7
30
2.37
1.13
2.0
3.1
5.90
4.87
e9/l
—
7
30
208
1983
1.56
1.09
15.1
12.1
—
—
—
0
0
23
154
1.55
1.09
1.5
1.5
—
—
—
0
0
15
90
1.71
1.07
1.3
2.7
0.67
0.68
%
0.04
15
90
67
551
1.31
1.02
3.6
3.0
9.32
7.86
mmol/l
1.24
56
468
9
49
1.87
1.00
1.2
1.1
—
—
—
0
0
7
36
1.97
0.98
1.0
1.3
—
—
—
0
0
21
142
1.53
0.96
2.7
2.6
69.55
72.52
e9/l
0.15
13
110
6
27
2.25
0.94
1.3
1.1
—
—
—
0
0
13
78
1.71
0.93
6.2
3.9
—
—
—
0
0
62
511
1.29
0.92
4.3
3.7
12.10
8.65
mg/mmol
0.16
36
325
50
400
1.32
0.92
3.7
3.6
1.01
1.02
kg/l
—
9
49
7
127
0.54
0.91
1.1
1.4
—
—
—
0
0
21
144
1.50
0.91
4.1
3.1
—
—
—
0
0
6
30
2.03
0.87
1.0
1.6
—
—
—
0
0
60
496
1.28
0.87
1.5
1.4
—
—
—
0
0
58
481
1.28
0.82
4.0
3.2
79.20
187.34
mg/l
0.37
36
319
23
165
1.44
0.81
1.2
1.2
—
—
—
0
0
16
106
1.55
0.81
1.3
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.7
—
—
—
0
0
6
33
1.84
0.79
1.2
1.1
—
—
—
0
0
17
115
1.52
0.79
2.8
8.2
—
—
—
0
0
20
141
1.46
0.77
5.1
4.6
—
—
—
0
0
209
2016
1.44
0.77
12.2
9.6
27.77
27.58
u/l
0.03
203
1957
38
301
1.31
0.76
1.8
1.7
1161.65
1189.51
nmol/l
0.06
26
229
5
26
1.94
0.71
1.6
1.3
15377.80
14524.07
e6/l
—
5
15
11
69
1.62
0.69
2.1
2.9
—
—
—
0
0
11
69
1.62
0.69
1.9
1.6
—
—
—
0
0
10
61
1.67
0.69
1.8
1.6
—
—
—
0
0
5
28
1.80
0.66
6.8
4.8
352.20
339.91
umol/l
—
5
23
7
44
1.61
0.65
1.4
1.4
—
—
—
0
0
76
667
1.21
0.65
3.3
3.5
28.88
38.87
ng/l
0.37
41
445
53
449
1.24
0.63
1.4
1.3
5.94
1.34
u/ml
0.63
13
128
54
460
1.23
0.61
3.8
3.6
0.00
0.01
estimate
0.50
20
159
16
115
1.42
0.58
2.8
3.7
1.40
0.62
%
—
5
41
9
59
1.55
0.55
1.7
2.4
—
—
—
0
0
178
1701
1.21
0.55
6.6
5.3
39.58
39.71
mmol/mol
0.06
169
1608
6
38
1.59
0.54
1.0
1.2
—
—
—
0
0
31
253
1.26
0.52
1.5
1.5
—
—
—
0
0
58
510
1.18
0.48
3.2
3.0
—
—
—
0
0
10
68
1.49
0.47
1.2
1.2
—
—
—
0
0
19
240
0.77
0.45
1.2
1.4
—
—
—
0
0
28
231
1.24
0.44
1.1
1.5
—
—
—
0
0
5
31
1.63
0.43
3.0
2.2
—
—
—
0
0
26
213
1.25
0.43
1.5
1.7
—
—
—
0
0
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
5
33
1.53
0.41
2.4
3.6
22.20
39.18
umol/l
—
5
28
5
34
1.48
0.40
2.2
2.3
—
—
—
0
0
46
403
1.18
0.40
1.9
1.5
21.36
21.48
nmol/l
0.02
40
351
19
151
1.28
0.40
1.7
1.4
—
—
—
0
0
16
124
1.31
0.40
2.9
3.4
1.23
1.23
mmol/l
—
10
111
44
499
0.85
0.39
1.6
1.7
1.22
1.40
mmol/l
1.03
37
427
9
68
1.34
0.38
1.1
1.3
—
—
—
0
0
5
37
1.36
0.37
3.2
1.7
—
—
—
0
0
14
108
1.32
0.36
2.0
2.3
—
—
—
0
0
30
256
1.20
0.35
1.7
1.4
464.00
512.45
titre
—
5
53
183
1775
1.16
0.35
4.6
4.3
6.03
5.92
mmol/l
0.49
167
1646
37
324
1.17
0.33
1.7
1.6
—
—
—
0
0
10
132
0.75
0.33
1.3
1.3
—
—
—
0
0
16
128
1.27
0.33
2.9
3.2
—
—
—
0
0
11
141
0.77
0.30
2.5
2.3
—
20.80
—
0
5
182
1771
1.14
0.29
3.9
3.8
1.30
1.30
mmol/l
0.02
169
1645
11
85
1.31
0.28
2.3
2.0
—
—
—
0
0
23
197
1.19
0.27
2.0
1.7
—
—
—
0
0
31
276
1.14
0.23
2.2
2.3
12.15
14.39
umol/l
0.71
31
259
29
325
0.88
0.23
1.3
1.3
36.76
30.65
iu/ml
—
7
110
72
677
1.09
0.22
4.3
4.6
2.15
1.94
ug/l
0.21
65
606
8
104
0.76
0.21
10.3
3.1
0.08
0.14
e6/l
—
8
99
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
7.91
—
0
11
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
6.92
—
0
13
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
201.11
—
0
14
6
50
1.21
0.20
3.5
2.6
—
—
—
0
0
6
53
1.14
0.19
7.7
2.9
—
—
—
0
0
44
408
1.10
0.18
1.9
1.8
—
—
—
0
0
5
70
0.71
0.17
2.6
4.6
—
—
—
0
0
10
83
1.21
0.15
2.2
3.6
—
—
—
0
0
7
90
0.77
0.14
2.1
2.2
—
—
—
0
0
9
108
0.83
0.13
3.2
2.2
—
—
—
0
0
70
729
0.94
0.12
3.2
2.6
—
—
—
0
0
12
104
1.16
0.12
2.3
1.9
—
—
—
0
0
12
105
1.15
0.11
2.3
1.9
—
—
—
0
0
12
105
1.15
0.11
2.3
1.9
—
—
—
0
0
32
300
1.08
0.10
1.3
1.3
6.86
6.06
u/ml
—
8
113
6
55
1.09
0.09
1.0
1.2
—
—
—
0
0
11
99
1.12
0.06
2.4
2.0
—
—
—
0
0
11
121
0.90
0.06
1.3
1.3
—
31.96
—
0
5
190
1887
1.04
0.05
4.8
4.7
2.76
2.78
mmol/l
0.09
175
1760
24
229
1.05
0.04
1.3
1.5
—
—
—
0
0
10
91
1.10
0.04
1.1
1.1
—
—
—
0
0
39
402
0.96
0.04
2.5
2.8
0.79
0.74
ug/l
0.13
28
249
10
108
0.92
0.03
1.2
1.2
—
—
—
0
0
48
470
1.03
0.03
3.7
2.4
320.24
6360.85
umol/l
1.79
41
406
19
198
0.96
0.02
1.6
1.7
—
—
—
0
0
10
106
0.94
0.01
1.7
1.8
—
—
—
0
0
185
1851
1.00
0.00
4.4
4.2
4.62
4.66
mmol/l
0.18
172
1740
184
1841
1.00
0.00
4.2
4.2
1.38
1.43
mmol/l
1.05
172
1719
11
105
1.05
0.00
2.4
1.6
—
—
—
0
0
6
64
0.94
-0.00
8.0
10.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.5
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.2
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.5
0.29
0.23
g/l
—
5
53
5
55
0.91
-0.00
1.0
1.3
—
3.33
—
0
8
5
55
0.91
-0.00
1.0
1.5
1.53
1.16
g/l
—
5
55
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
1633.86
—
0
7
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.2
—
—
—
0
0
6
59
1.02
-0.00
2.0
1.3
—
64.29
—
0
7
6
60
1.00
-0.00
2.2
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.20
—
0
5

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_MECKELS_DIVERTICULUM – Meckel's diverticulum

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).